CN115317077B - Thrombus taking device - Google Patents

Abstract

The embodiment of the invention provides a thrombus removal device, and relates to the field of medical instruments. The thrombus taking device comprises a first catheter, a second catheter, a thrombus catcher and a thrombus interceptor, wherein the second catheter is slidably arranged in the first catheter in a penetrating manner, the thrombus catcher comprises a hollow catching net and a catching conveying wire, the hollow catching net is connected with the catching conveying wire, the catching conveying wire is slidably arranged between the first catheter and the second catheter, the thrombus interceptor comprises a catching net and a catching conveying wire, the catching net is connected with the catching conveying wire, the catching conveying wire is slidably arranged in the second catheter, and the catching net is released at the far end of thrombus to prevent thrombus from escaping to the far end of the blood vessel, so that the thrombus which is not cleared from blocking other normal branch blood vessels, the thrombus taking frequency is reduced, and the thrombus taking effect is improved.

Description

Thrombus taking device

Technical Field

The invention relates to the field of medical instruments, in particular to a thrombus taking device.

Background

Stroke is a common type of disease in medicine, and has become the first cause of death in humans. Stroke is classified into hemorrhagic stroke and ischemic stroke. The proportion of cerebral ischemic stroke is about 80%. The number of the diseases is large every year, and the diseases show a trend of youthfulness. At present, the recanalization rate of the vein thrombolysis treatment is low, and the mechanical thrombus removal treatment in blood vessels is beneficial to improving the recanalization rate of cerebral apoplexy blood vessels. The current clinical common thrombus removal modes comprise: the thrombus taking bracket is used for taking thrombus and the catheter is used for sucking the thrombus.

In the prior art, thrombus cannot be completely removed well at one time by adopting a bracket thrombus taking and catheter suction embolus, so that the thrombus needs to be taken out for multiple times, the operation difficulty is increased, the operation time is longer, a patient cannot be treated in time, the treatment effect is poorer, and finally serious complications can be caused.

Disclosure of Invention

The invention provides a thrombus removal device which can improve thrombus removal effect and reduce thrombus removal times.

Embodiments of the invention may be implemented as follows:

an embodiment of the present invention provides a thrombus removal device, including:

a first conduit;

a second catheter slidably disposed through the first catheter;

the thrombus capture device comprises a hollow capture net and a capture and transmission wire, wherein the hollow capture net is connected with the capture and transmission wire, the capture and transmission wire is slidably arranged between the first conduit and the second conduit, the capture and transmission wire is used for pushing the hollow capture net out of the far end of the first conduit so as to enable the hollow capture net to be in a release state, or the capture and transmission wire is used for pulling the hollow capture net back between the first conduit and the second conduit so as to enable the hollow capture net to be stored between the first conduit and the second conduit, and the hollow capture net is in a storage state; and

the thrombus interceptor, the thrombus interceptor includes that the interception net and interception are defeated to be sent a silk, the interception net with the interception is carried the silk and is connected, the interception is defeated to be sent a silk slidable set up in the second pipe, the interception is defeated to be sent a silk and is used for with the interception net is released the distal end of second pipe, so that the interception net is in the release state, or the interception is defeated to be sent a silk and is used for with the interception net is pulled back in the second pipe, so that the interception net accomodate in the second pipe, so that the interception net is in and accomodates the state.

Optionally, the hollow capture net is sleeved outside the second conduit with the hollow capture net in the stowed state.

Optionally, the embolectomy device further comprises a third catheter, the first catheter being slidably disposed through the third catheter.

Optionally, the thrombus removal device further comprises a first hemostatic valve, wherein the first hemostatic valve comprises a first male luer connector, a first valve body and a first hemostatic connector which are connected in sequence, the first male luer connector is communicated with the proximal end connector of the third catheter, and the first hemostatic connector is hermetically connected with the outer wall of the first catheter.

Optionally, the thrombus extraction device further comprises a T-shaped hemostatic valve, the T-shaped hemostatic valve comprises a second male luer, a second valve body, a second hemostatic connector and an air exhaust tube communicated with the second valve body, the second male luer and the proximal end of the first catheter are sequentially connected, and the second hemostatic connector is simultaneously and hermetically connected with the outer wall of the second catheter and the outer wall of the capturing and delivering wire.

Optionally, the thrombus removal device further comprises a second hemostatic valve, the second hemostatic valve is the same as the first hemostatic valve, a distal end of the second hemostatic valve is communicated with a proximal end of the second catheter, and the proximal end of the second hemostatic valve is hermetically connected with the intercepting delivery wire.

Optionally, the inner surface and the outer surface of the hollow catching net are covered with silica gel layers, and the silica gel layers are used for sealing the grid gaps of the hollow catching net.

Optionally, the hollow capture net comprises a cylindrical net and a funnel net woven with each other, and when the hollow capture net is in a release state, the distal end port of the first conduit and the funnel net can form a radial peripheral wall sealing connection during the release process, and the cylindrical net, the funnel net and the first conduit are communicated in sequence.

Optionally, the thrombus capture device further comprises a fixing ring and a first flexible spiral tube, the fixing ring is arranged in the first guide tube, the funnel net, the fixing ring, the first flexible spiral tube and the capture conveying wire are sequentially connected, and the fixing ring is communicated with the funnel net.

Optionally, the intercepting net is a spherical intercepting net.

Optionally, the number of the intercepting nets is multiple, the intercepting nets are connected in sequence, the intercepting nets are formed by weaving multiple strands of intercepting wires, and at least one strand of intercepting wires is made of a developing material.

Optionally, the thrombus interceptor further comprises a flexible head, a near-end developing part and a second flexible spiral tube, wherein the flexible head, the intercepting net, the near-end developing part and the second flexible spiral tube are sequentially connected.

Optionally, the first pipe comprises a connector, a pipe body and a sheath, the connector is communicated with the pipe body, and the sheath is sleeved on the outer wall of the joint of the connector and the pipe body.

Optionally, the catheter tube body is a multilayer composite catheter, and the catheter tube body includes a PTFE tube layer, a braid layer, and a plastic layer, which are sequentially disposed along a radial direction.

Optionally, the hardness of the plastic layer is progressively greater from the distal end to the proximal end.

Optionally, the catheter tube is a single layer catheter.

The thrombus removal device of the embodiment of the invention has the beneficial effects that:

an embodiment of the invention provides a thrombus taking device, which comprises a first catheter, a second catheter, a thrombus capture device and a thrombus blocker, wherein the second catheter is slidably arranged in the first catheter in a penetrating manner, the thrombus capture device comprises a hollow capture net and a capture conveying wire, the hollow capture net is connected with the capture conveying wire, the capture conveying wire is slidably arranged between the first catheter and the second catheter, the capture conveying wire is used for pushing the hollow capture net out of the distal end of the first catheter so as to enable the hollow capture net to be in a release state, or the capture conveying wire is used for pulling the hollow capture net back between the first catheter and the second catheter so as to enable the hollow capture net to be contained between the first catheter and the second catheter, the hollow capture net is in a containing state, the thrombus blocker comprises a capture net and a capture conveying wire, the capture net is connected with the capture conveying wire, the capture conveying wire is slidably arranged in the second catheter, the capture conveying wire is used for pushing the capture net out of the distal end of the second catheter so as to enable the capture net to be in a release state, or the capture conveying wire is used for pulling the capture net back into the second catheter so as to enable the capture wire to be contained in the second catheter, and the capture conveying wire to be in a containing state.

The second catheter comprising the intercepting net in the storage state and the first catheter comprising the hollow catching net in the storage state penetrate into a blood vessel, the far end of the second catheter penetrates out of the far end of the first catheter until the far end of the second catheter is positioned at the far end of thrombus in the blood vessel, the far end of the first catheter is positioned at the near end of the thrombus, and then the intercepting and conveying wire is pushed to push the intercepting net out of the far end of the second catheter until the intercepting net is in the release state so as to prevent the thrombus from escaping to the far end of the blood vessel. Meanwhile, the catching transmission wire is pushed to push the hollow catching net out of the far end of the first guide pipe, so that the hollow catching net is in a release state, thrombus is collected, after the thrombus is collected, the blocking net is accommodated into the second guide pipe, the hollow catching net is accommodated between the first guide pipe and the second guide pipe, and finally the first guide pipe and the second guide pipe are withdrawn simultaneously, so that the thrombus taking process is completed.

Drawings

To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required in the embodiments will be briefly described below, and it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope.

FIG. 1 is a schematic view of a thrombectomy device provided in an embodiment of the present invention;

FIG. 2 is a schematic view of a thrombus interceptor provided in an embodiment of the present invention;

FIG. 3 is a schematic view of a thrombus trap provided in an embodiment of the present invention;

FIG. 4 is a schematic view of a first catheter provided in an embodiment of the present invention;

FIG. 5 is a schematic view of a T-shaped hemostasis valve provided in an embodiment of the invention;

fig. 6 is a schematic view of a first hemostasis valve provided in an embodiment of the invention.

An icon: 1000-thrombus removal device; 100-a first conduit; 110-a catheter tube; 120-a connector; 130-a sheath; 200-a second conduit; 300-thrombus catcher; 310-hollow catching net; 311-cylinder net; 312-a funnel net; 320-capturing and conveying the wire; 330-a fixed ring; 340-a first flexible helical tube; 400-a thrombus interceptor; 410-an interception net; 420-intercepting the transmission wire; 430-a flexible head; 440-a proximal development; 450-a second flexible coil; 500-a third conduit; 600-a first hemostatic valve; 610-a first male luer; 620-a first valve body; 630-a first hemostatic joint; 631-rotary valve cover; 632-a valve cover mandrel; 633-hemostatic valve sheet; 640-a female connector; a 700-T hemostatic valve; 710-a second male luer; 720-a second valve body; 730-a second hemostatic joint; 740-an exhaust tube; 800-a second hemostatic valve; 900-extension tube.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

In the description of the present invention, it should be noted that if the terms "upper", "lower", "inside", "outside", etc. indicate an orientation or a positional relationship based on that shown in the drawings or that the product of the present invention is used as it is, this is only for convenience of description and simplification of the description, and it does not indicate or imply that the device or the element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention.

Furthermore, the appearances of the terms "first," "second," and the like, if any, are only used to distinguish one description from another and are not to be construed as indicating or implying relative importance.

It should be noted that the features of the embodiments of the present invention may be combined with each other without conflict.

Stroke is a common type of disease in medicine, and has become the first cause of death in humans. Cerebral apoplexy is classified into hemorrhagic stroke and ischemic stroke. Among them, ischemic stroke accounts for about 80%. The number of the diseases is large every year, and the diseases show a trend of youthfulness. The recanalization rate of the existing venous thrombolysis treatment is low, and the mechanical thrombus removal treatment in blood vessels is beneficial to improving the recanalization rate of cerebral apoplexy blood vessels. The current clinical common thrombus removal modes comprise: the thrombus taking bracket is used for taking thrombus and the catheter is used for sucking the thrombus.

Specifically, a doctor needs to puncture a small opening of about 2 mm in the femoral artery of a patient, and uses a catheter to deliver an embolectomy device (such as a catheter or an embolectomy stent) into the blocked blood vessel, so as to perform embolectomy treatment and restore recanalization of the blood vessel.

However, in the existing thrombus taking mode, the stent thrombus taking is difficult to finish at one time, the microcatheter is required to be used for multiple times to convey the thrombus taking stent to release after the thrombus passes through, the thrombus is grabbed, the thrombus can be damaged when the thrombus taking stent passes through, and then the damaged thrombus escapes to the far end.

The mode of adopting the catheter to suck the thrombus needs to be sucked after being close to the thrombus, but the thrombus suction effect is better only near a suction port, other areas are often difficult to clear, the thrombus is easy to break in the thrombus taking process by the two operation modes, the broken thrombus escapes to the tiny blood vessel at the farther end and is difficult to clear, the better thrombus taking effect cannot be realized, meanwhile, the thrombus which is not cleared can be blocked to other normal branch blood vessels by taking the thrombus for many times, the thrombus is taken for many times, the possibility that the inner wall of the blood vessel is damaged by instruments is improved, the operation difficulty is increased, the operation time is longer, a patient cannot be treated in time, the treatment effect is poorer, and serious complications are caused.

In conclusion, the thrombus cannot be completely removed at one time well by adopting the stent thrombus taking and the catheter suction thrombus, so that the thrombus needs to be taken for multiple times, the operation difficulty is increased, the operation time is longer, the patient cannot be treated in time, the treatment effect is poorer, and serious complications are caused.

In view of the above, referring to fig. 1-6, the present embodiment provides athrombus removal device 1000, which can solve the above problem, and will be described in detail below.

Referring first to fig. 1, an embodiment of the invention provides anembolectomy device 1000, wherein theembolectomy device 1000 comprises afirst catheter 100, asecond catheter 200, athrombus catcher 300 and athrombus blocker 400, and thesecond catheter 200 is slidably disposed in thefirst catheter 100. Thethrombus capture device 300 includes a hollow capture net 310 and acapture transport wire 320, wherein the hollow capture net 310 and thecapture transport wire 320 are connected, thecapture transport wire 320 is slidably inserted between thefirst catheter 100 and thesecond catheter 200, thecapture transport wire 320 is used to push the hollow capture net 310 out of the distal end of thefirst catheter 100 so that the hollow capture net 310 is in a released state, or thecapture transport wire 320 is used to pull the hollow capture net 310 back between thefirst catheter 100 and thesecond catheter 200 so that the hollow capture net 310 is received in thefirst catheter 100 and thesecond catheter 200, and the hollow capture net 310 is in a received state.

It should be noted that, in order to describe the structure of theembolectomy device 1000 more clearly, in the present application, "distal" refers to the end that is distal from the operator during the surgical procedure, and "proximal" refers to the end that is proximal to the operator during the surgical procedure.

Thethrombus interceptor 400 includes an intercepting net 410 and an intercepting and deliveringwire 420, wherein the intercepting net 410 and the intercepting and deliveringwire 420 are connected, the intercepting and deliveringwire 420 is slidably disposed on thesecond catheter 200, the intercepting and deliveringwire 420 is used for pushing the intercepting net 410 out of the distal end of thesecond catheter 200 to make the intercepting net 410 in a release state, or the intercepting and deliveringwire 420 is used for pulling the intercepting net 410 back into thesecond catheter 200 to make the intercepting net 410 received in thesecond catheter 200 to make the intercepting net 410 in a receiving state.

Thesecond catheter 200 containing the blocking net 410 in the storage state and thefirst catheter 100 containing the hollow capture net 310 in the storage state are simultaneously threaded into the blood vessel with thrombus, and the distal end of thesecond catheter 200 passes through the distal end of thefirst catheter 100 until the distal end of thesecond catheter 200 is positioned at the distal end of the thrombus in the blood vessel and the distal end of thefirst catheter 100 is positioned at the proximal end of the thrombus, and then the blockingtransfusion wire 420 is pushed to push the blocking net 410 out of the distal end of thesecond catheter 200 until the blocking net 410 is in the release state to block the thrombus from escaping to the distal end of the blood vessel.

Meanwhile, the catching and conveyingwire 320 is pushed to push the hollow catching net 310 out of the far end of thefirst conduit 100, so that the hollow catching net 310 is in a releasing state, thrombus is collected, after the thrombus is collected, theinterception net 410 is accommodated in thesecond conduit 200, the hollow catching net 310 is accommodated between thefirst conduit 100 and thesecond conduit 200, and finally, the thrombus captured by thefirst conduit 100, thesecond conduit 200 and the hollow catching net 310 is withdrawn from the blood vessel, so that the thrombus removal process is completed.

Of course, it is also possible that the blocking net 410 is not received in thesecond catheter 200, the blocking net 410 is received in thefirst catheter 100 together with the hollow catching net 310 and thesecond catheter 200 in the released state, and thefirst catheter 100 is integrally drawn out of the blood vessel, and the thrombus is removed in this way, so that the thrombus at the distal end can be prevented from entering thesecond catheter 200 and being broken after being caught by the blockingnet 410.

Because theinterception net 410 is released at the far end of the thrombus, the thrombus can be prevented from escaping to the far end of the blood vessel, the thrombus which is not cleared is prevented from blocking other normal branch blood vessels, the thrombus taking frequency is reduced, and the thrombus taking effect is improved.

In order to facilitate the delivery of thefirst catheter 100 and thesecond catheter 200 to the thrombus position in the blood vessel and avoid the blood overflow in the blood vessel, in this embodiment, thethrombus removal device 1000 further includes athird catheter 500 and a firsthemostatic valve 600, thefirst catheter 100 is slidably disposed through thethird catheter 500, the firsthemostatic valve 600 includes a firstmale luer 610, afirst valve body 620 and a firsthemostatic connector 630, which are connected in sequence, the firstmale luer 610 is communicated with the proximal connector of thethird catheter 500, the firsthemostatic connector 630 is hermetically connected with the outer wall of thefirst catheter 100, and thethird catheter 500 establishes a delivery channel for the delivery of thefirst catheter 100 and thesecond catheter 200.

Specifically, in this embodiment, the firsthemostatic valve 600 is a Y-shaped hemostatic valve, which has afemale connector 640 communicating with thefirst valve body 620, so as to facilitate the delivery of relevant drugs during the operation.

As shown in fig. 5, the proximal end connector of thethird catheter 500 is a female luer connector, the firsthemostatic connector 630 includes arotary valve cover 631, avalve cover mandrel 632, and ahemostatic valve sheet 633, thehemostatic valve sheet 633 is a flexible silicone gasket, a valve core flow channel is defined in thevalve cover mandrel 632, therotary valve cover 631 and thevalve cover mandrel 632 are in threaded fit, the valve core flow channel, thehemostatic valve sheet 633, and thefirst valve body 620 are sequentially communicated, and in a process that therotary valve cover 631 rotates relative to thevalve cover mandrel 632, thehemostatic valve sheet 633 can be squeezed, a central hole of thehemostatic valve sheet 633 can be reduced until the central hole is sealed with an outer wall of thefirst catheter 100, so as to prevent blood in a blood vessel from overflowing through a gap between thefirst catheter 100 and thethird catheter 500.

As shown in fig. 6, theembolectomy device 1000 further comprises a T-shapedhemostatic valve 700 and a secondhemostatic valve 800, the T-shapedhemostatic valve 700 comprises a secondmale luer 710, asecond valve body 720, a secondhemostatic connector 730, and asuction tube 740 communicated with thesecond valve body 720, which are connected in sequence, thesuction tube 740 is further connected with anextension tube 900, theextension tube 900 is used for being connected with an extracorporeal negative pressure device, theextension tube 900 comprises an extension tube body and a female luer communicated with the extension tube body, the extension tube body can be a single-layer tube body with a plastic layer, for example, the plastic layer is made of TPU (thermoplastic polyurethane elastomer) or PVC (polyvinyl chloride), and can also be a multi-layer composite catheter, and the female luer of theextension tube 900 is connected with the extracorporeal negative pressure device.

The secondmale luer 710 is communicated with the proximal catheter connector of thefirst catheter 100, the proximal catheter connector of thefirst catheter 100 is a female luer, the secondhemostatic connector 730 is hermetically connected with the outer wall of thesecond catheter 200 and the outer wall of the capturing and deliveringwire 320, so as to avoid blood overflow, and the secondhemostatic connector 730 and the firsthemostatic connector 630 have the same structure.

The secondhemostatic valve 800 and the firsthemostatic valve 600 have the same structure, and are not described herein again, the distal end of the secondhemostatic valve 800 is communicated with the proximal end of thesecond catheter 200, and the proximal end of the secondhemostatic valve 800 is hermetically connected to the intercepting and deliveringwire 420, that is, the secondhemostatic valve 800 at the proximal end of the secondhemostatic valve 800 is hermetically connected to the surface of the intercepting and deliveringwire 420, so as to prevent blood from overflowing.

In the present embodiment, thefirst guide pipe 100, thesecond guide pipe 200 and thethird guide pipe 500 have the same structure, except that the length of thefirst guide pipe 100 is smaller than that of thesecond guide pipe 200, the length of thefirst guide pipe 100 is greater than that of thethird guide pipe 500, the inner diameter of thethird guide pipe 500 is greater than that of thefirst guide pipe 100, and the inner diameter of thefirst guide pipe 100 is greater than that of thesecond guide pipe 200.

In addition, referring to fig. 2, taking thefirst catheter 100 as an example, for detailed description, thefirst catheter 100 includes aconnector 120, acatheter tube 110 and asheath 130, theconnector 120 is communicated with thecatheter tube 110, thesheath 130 is sleeved on an outer wall of a junction of theconnector 120 and thecatheter tube 110, and theconnector 120 is a female luer so as to be matched with a secondmale luer 710 of the T-shapedhemostatic valve 700.

Meanwhile, in this embodiment, thecatheter tube body 110 is a multi-layer composite catheter, thecatheter tube body 110 includes a PTFE (polytetrafluoroethylene) tube layer, a braid and a plastic layer, which are sequentially disposed along a radial direction, the material of the plastic layer may be TPU (thermoplastic polyurethane elastomer), pebax (polyether block polyamide), PA (polyamide), etc., and the braid may be a metal braid or a nylon braid.

Particularly, the inlayer ofcatheter body 110 is the PTFE pipe layer, the outermost layer ofcatheter body 110 is the plastic layer, wherein, the density degree of weaving layer is sparse from the distal end to the near-end gradually, the hardness of plastic layer is progressively bigger from the distal end to the near-end, so that the part thatcatheter body 110 is close to the distal end more is softer, the position thatcatheter body 110 is close to the near-end more is harder, can adapt to the comparatively crooked blood vessel of distal end like this, improvecatheter body 110's trafficability characteristic, reduce the damage to blood vessel,catheter body 110's near-end is harder, conveniently carry out the propelling movement ofcatheter body 110.

Of course, thecatheter tube 110 may be a single layer catheter, which may be understood as a single layer tube having only a plastic layer, and the type ofcatheter tube 110 is not limited herein.

In addition, a hydrophilic coating, such as a polyvinylpyrrolidone coating, may also be provided on the outer wall of thecatheter tube 110, or in other embodiments, a silicone oil coating may also be provided on the outer wall of thecatheter tube 110.

It should be noted that, when the hollow capturing net 310 is in the storage state, the hollow capturing net 310 is sleeved outside thesecond catheter 200, wherein the capturing and transportingwire 320 passes through the secondhemostatic joint 730 of the T-shapedhemostatic valve 700, and the intercepting and transportingwire 420 passes through the hemostatic joint of the secondhemostatic valve 800, so as to facilitate pushing or withdrawing of the capturing and transportingwire 320 and the intercepting and transportingwire 420.

In order to enhance the cleaning ability for thrombus, in this embodiment, the inner surface and the outer surface of the hollow capturing net 310 are covered with a silica gel layer, the silica gel layer is used to seal the mesh gaps of the hollow capturing net 310, and in a released state, the outer surface of the hollow capturing net 310 abuts against the inner wall of the blood vessel to temporarily block the blood flow from approaching the proximal end of the thrombus.

Specifically, the hollow catching net 310 includes acylindrical net 311 and a funnel net 312 which are woven to cross each other, thecylindrical net 311 and thefunnel net 312 are connected, and the outer diameter of thecylindrical net 311 in the released state may be just equal to the inner diameter of the blood vessel or slightly larger than the inner diameter of the blood vessel, but the outer diameter of thecylindrical net 311 may be slightly smaller than the inner diameter of the blood vessel.

Thecylinder net 311, thefunnel net 312 and thefirst catheter 100 are sequentially communicated, meanwhile, thefirst catheter 100, theexhaust tube 740 of the T-shapedhemostatic valve 700 and theextension tube 900 are sequentially communicated, the hollow capture net 310 is pushed out and is in a release state, a distal end port of thefirst catheter 100 and the funnel net 312 can form radial peripheral wall sealing connection in the release process, and the hollow capture net 310 can perform negative pressure adsorption on thrombus by connecting an external negative pressure device (not shown) at theextension tube 900, so that the thrombus is rapidly captured. In addition, in the present embodiment, the hollow capturing net 310 is made of memory alloy, and the hollow capturing net 310 is a net structure, which is relatively flexible and can conform to the tortuous artery.

In the process of sucking the thrombus, the hollow capture net 310, thefirst catheter 100, thesuction tube 740 of the T-shapedhemostatic valve 700 and theextension tube 900 are communicated in sequence, and since theextension tube 900 is communicated with the in vitro negative pressure device, the thrombus can be sucked by the distal end of thecylindrical net 311 deployed by the hollow capture net 310, and can be sucked into the lumen of the first catheter, and then enter the in vitro negative pressure device after reaching theextension tube 900 of the T-shapedhemostatic valve 700, so as to collect the thrombus.

Specifically, since the extracorporeal negative pressure device generates a fixed negative pressure value P, and since the inner diameter of the cylinder net 311 in the released state is much larger than that of thefirst catheter 100, when thrombus is sucked, the suction force on thrombus is represented by the following formula: f = P × S, it is known that when the suction pressure P is a constant value, the contact area S of suction, that is, the area of the distal end port of thecylindrical mesh 311 is increased, the suction force F is greatly increased, the capturing force and the area for the thrombus are both increased, and the capability of surgical thrombus extraction is further increased, so that the whole capturing and removal of the thrombus can be realized, and multiple times of thrombus extraction can be avoided.

With continued reference to fig. 3, in the present embodiment, thethrombus capture device 300 further includes a fixingring 330 and a firstflexible coil 340, the fixingring 330 is disposed in thefirst catheter 100, the proximal end of thefunnel net 312 is fixedly connected to the fixingring 330, and the fixingring 330 is communicated with thefunnel net 312.

Specifically, thefunnel net 312, the fixingring 330, the firstflexible spiral tube 340 and the capturing and transportingwire 320 are sequentially connected, the firstflexible spiral tube 340 is of a spring structure to improve the flexibility of thethrombus capturing device 300 and facilitate the thrombus capturing device to be inserted into a curved blood vessel along with thefirst catheter 100, and in addition, the outer wall of the firstflexible spiral tube 340 is provided with a PTFE lubricating layer to reduce the friction coefficient so as to facilitate the sliding between thefirst catheter 100 and thesecond catheter 200.

In addition, with continued reference to fig. 2, in order to improve the blocking capability against thrombus that may escape, the blockingnets 410 are spherical, and the number of the blocking nets 410 is plural, and the outer diameter of the spherical blocking nets is equal to the inner diameter of the blood vessel or slightly larger than the inner diameter of the blood vessel, thereby enhancing the blocking capability against thrombus.

Specifically, in the present embodiment, the three interceptingnets 410 are sequentially connected to improve the probability of intercepting thrombus, the three interceptingnets 410 are woven by sixteen strands of intercepting wires, specifically, the sixteen strands of intercepting wires include eight strands of forward intercepting wires and eight strands of reverse intercepting wires, where the forward intercepting wires and the reverse intercepting wires can be understood as metal wires that are woven to cross each other, and it should be noted that the interceptingnets 410 may be made of memory alloy, so as to be conveniently deployed after being released.

In other embodiments, the shape of the intercepting net 410 may also be a disk or a rectangle for intercepting thrombus, and the shape of the intercepting net 410 is not limited herein.

In order to conveniently know the release states of the three interceptingscreens 410, at least one of the intercepting wires is made of a developing material, and specifically, one of the forward intercepting wires and one of the reverse intercepting wires are made of a developing material, so that the release states of the three interceptingscreens 410 can be displayed under X-ray.

In addition, in this embodiment, thethrombus interceptor 400 further comprises aflexible head 430, a proximal developingmember 440 and a secondflexible spiral tube 450, theflexible head 430, the intercepting net 410, the proximal developingmember 440 and the secondflexible spiral tube 450 are sequentially connected, theflexible head 430 is specifically a metal spring soft head with a core wire, and theflexible head 430 can be made of a developing material so as to be capable of developing the position of theflexible head 430 under X-ray. Meanwhile, the secondflexible spiral tube 450 and the firstflexible spiral tube 340 have the same structure, and the outer wall of the secondflexible spiral tube 450 is also provided with a PTFE lubricating layer, so that the friction coefficient is reduced.

Next, the operation method of thethrombectomy device 1000 according to the present embodiment will be described in detail:

after preparing for vascular puncture during the operation, thethird catheter 500 is placed at the proximal end of the thrombus of the diseased blood vessel to establish a delivery passage, and then thesecond catheter 200 containing the blocking net 410 in the storage state and thefirst catheter 100 containing the hollow catching net 310 in the storage state are pushed to penetrate into the blood vessel, and the distal end of thefirst catheter 100 and the distal end of thesecond catheter 200 are close to the thrombus.

Thesecond catheter 200 is then advanced relative to thefirst catheter 100 so that thesecond catheter 200 is passed through the thrombus, where passing thesecond catheter 200 through the thrombus is understood to mean that the distal end of thesecond catheter 200 passes through the gap between the inner wall of the blood vessel and the thrombus, thereby bringing the distal end of thesecond catheter 200 close to the distal end of the thrombus.

It should be noted that, in order to facilitate the operator to accurately release the hollow capturing net 310 and the intercepting net 410, the capturing and transportingwire 320 and the intercepting and transportingwire 420 are provided with start scale marks and end scale marks.

Then, theinterception mesh 410 delivery wire outside the proximal end of the secondhemostatic valve 800 is pushed gently to the start scale mark, theinterception mesh 410 starts to be released at the distal end of the thrombus, and it should be noted that thesecond catheter 200 is retracted while theinterception mesh 410 delivery wire is pushed until theinterception mesh 410 delivery wire is pushed to the end scale mark on theinterception mesh 410 delivery wire, and at this time, theinterception mesh 410 is released.

Meanwhile, thesecond catheter 200 is retracted into thefirst catheter 100, the intercepting net 410 starts to block the thrombus from escaping towards the distal end, then thefirst catheter 100 is pushed slightly, the distal end of thefirst catheter 100 is close to the proximal end of the thrombus, the capturing and transmittingwire 320 outside the proximal end of the T-shapedhemostatic valve 700 is pushed to the initial scale line, the hollow capturing net 310 starts to be released at the proximal end of the thrombus, the capturing and transmittingwire 320 is pushed, thefirst catheter 100 is retracted, a part of the hollow capturing net 310 is slowly released, but the hollow capturing net 310 cannot be completely separated from the distal end port of thefirst catheter 100.

When the end scale mark of the capturing and conveyingwire 320 is reached, the pushing of the capturing and conveyingwire 320 is stopped, at this time, the distal end port of thefirst guide pipe 100 is in sealing connection with the radial peripheral wall of thefunnel net 312, the outer diameter of thecylindrical net 311 in the release state can be just equal to the inner diameter of the blood vessel, the temporary blood flow blocking is carried out, and meanwhile, the thrombus suction operation is prepared.

At this time, the secondhemostatic joint 730 of the T-shapedhemostatic valve 700 is contracted and closed, an external negative pressure device is used to suck at theextension tube 900 of the T-shapedhemostatic valve 700, and the suction area of the distal end port of thecylinder net 311 is large, so that the thrombus is integrally sucked and captured, that is, the thrombus is accommodated in the hollow capture net 310, and then the thrombus is integrally recovered by pulling back thefirst catheter 100, thesecond catheter 200, thecapture transport wire 320 and theinterception transport wire 420, and the negative pressure suction is continuously performed while the thrombus is recovered, so that the thrombus does not escape to the distal end. Lastfirst pipe 100,second pipe 200, net 310 is caught to cavity, net 410 is caught to interception and thrombus are all accomodate into the lumen ofthird pipe 500 completely, extractthird pipe 500 from the blood vessel, accomplish the endovascular embolectomy process, for prior art, theembolectomy device 1000 of this application is bigger to the thrombus suction power, and simultaneously, net 410 can prevent that the thrombus from escaping, and then can once only catch and aspirate the thrombus, avoid the thrombus of not clearing up to other normal branch vessels, the effect of getting the embolus has been improved, reduce the number of times of getting the embolus.

It should be noted that, most of the thrombus will be removed in the general suction process, and part of the escaped distal thrombus may be sucked away or pulled back into thethird catheter 500 during the recovery process, and in addition, an extracorporeal negative pressure device may be connected to thefemale connector 640 of the firsthemostatic valve 600 during the recovery process, and the negative pressure suction may be performed at the same time, so as to improve the suction effect.

The above description is only for the specific embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (8)

1. A thrombectomy device, comprising:

a first conduit (100);

a second catheter (200), said second catheter (200) being slidably disposed through said first catheter (100);

a thrombus capture device (300), the thrombus capture device (300) comprising a hollow capture net (310) and a capture transport wire (320), the hollow capture net (310) and the capture transport wire (320) being connected, the capture transport wire (320) being slidably disposed between the first catheter (100) and the second catheter (200), the capture transport wire (320) being configured to push the hollow capture net (310) out of the distal end of the first catheter (100) such that the hollow capture net (310) is in a released state, or the capture transport wire (320) being configured to pull the hollow capture net (310) back between the first catheter (100) and the second catheter (200) such that the hollow capture net (310) is housed between the first catheter (100) and the second catheter (200), the hollow capture net (310) being in a housed state, an inner surface and an outer surface of the hollow capture net (310) being covered with a silicone layer, the silicone layer sealing the capture net (310) gap; the hollow capturing net (310) comprises a cylindrical net (311) and a funnel net (312) which are mutually crossed and woven, when the hollow capturing net (310) is in a release state, the distal end port of the first conduit (100) and the funnel net (312) can form radial peripheral wall sealing connection in the release process, the cylindrical net (311), the funnel net (312) and the first conduit (100) are sequentially communicated, the thrombus capturing device (300) further comprises a fixing ring (330) and a first flexible spiral pipe (340), the fixing ring (330) is arranged in the first conduit (100), the funnel net (312), the fixing ring (330), the first flexible spiral pipe (340) and the capturing and conveying wire (320) are sequentially connected, and the fixing ring (330) is communicated with the funnel net (312);

a thrombus interceptor (400), said thrombus interceptor (400) comprising an intercepting screen (410) and an intercepting and delivering wire (420), said intercepting screen (410) and said intercepting and delivering wire (420) being connected, said intercepting and delivering wire (420) being slidably disposed within said second catheter (200), said intercepting and delivering wire (420) being adapted to push said intercepting screen (410) out of the distal end of said second catheter (200) such that said intercepting screen (410) is in a released state, or said intercepting and delivering wire (420) being adapted to pull said intercepting screen (410) back into said second catheter (200) such that said intercepting screen (410) is received within said second catheter (200), said intercepting screen (410) being in a received state, wherein said intercepting screen (410) is a spherical intercepting screen and the number of said intercepting screens (410) is plural, the plurality of said intercepting screens (410) being connected in sequence, the plurality of said intercepting screens (410) being formed by a woven intercepting wire, wherein at least one strand of said intercepting wire is made of a visualization material;

a third catheter (500), the first catheter (100) being slidably disposed through the third catheter (500);

the first hemostatic valve (600), the first hemostatic valve (600) comprises a first male luer connector (610), a first valve body (620) and a first hemostatic connector (630), which are connected in sequence, the first male luer connector (610) is communicated with the proximal connector of the third catheter (500), and the first hemostatic connector (630) is hermetically connected with the outer wall of the first catheter (100); and

the T-shaped hemostatic valve (700) comprises a second male luer connector (710), a second valve body (720), a second hemostatic connector (730) and an air suction pipe (740) communicated with the second valve body (720), wherein the second male luer connector (710) is communicated with a proximal catheter connector of the first catheter (100), and the second hemostatic connector (730) is simultaneously in sealing connection with the outer wall of the second catheter (200) and the outer wall of the capturing and conveying wire (320).

2. The embolectomy device of claim 1, wherein the hollow capture net (310) is sleeved outside the second conduit (200) with the hollow capture net (310) in a stowed state.

3. The embolectomy device of claim 1, further comprising a second hemostatic valve (800), wherein the second hemostatic valve (800) is the same as the first hemostatic valve (600), wherein a distal end of the second hemostatic valve (800) is in communication with a proximal end of the second catheter (200), and wherein a proximal end of the second hemostatic valve (800) is sealingly connected to the intercepting delivery wire (420).

4. The embolectomy device of claim 1, wherein the thrombus interceptor (400) further comprises a flexible head (430), a proximal visualization member (440), and a second flexible coil (450), the flexible head (430), the intercepting screen (410), the proximal visualization member (440), and the second flexible coil (450) being connected in sequence.

5. The embolectomy device of claim 1, wherein the first catheter (100) comprises a connector (120), a catheter tube (110) and a sheath (130), the connector (120) is communicated with the catheter tube (110), and the sheath (130) is sleeved on the outer wall of the joint of the connector (120) and the catheter tube (110).

6. The thrombectomy device of claim 5, wherein the catheter tube (110) is a multi-layer composite catheter, and the catheter tube (110) comprises a PTFE tube layer, a woven layer and a plastic layer sequentially arranged in a radial direction.

7. The embolectomy device of claim 6, wherein the hardness of the plastic layer increases gradually from the distal end to the proximal end.

8. The embolectomy device of claim 5, wherein the catheter tube (110) is a single-layer catheter.

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