CN115192304A - Blood cooling catheter and blood cooling equipment - Google Patents
Blood cooling catheter and blood cooling equipmentDownload PDFInfo
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- CN115192304A CN115192304ACN202210834940.5ACN202210834940ACN115192304ACN 115192304 ACN115192304 ACN 115192304ACN 202210834940 ACN202210834940 ACN 202210834940ACN 115192304 ACN115192304 ACN 115192304A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0001—Body part
- A61F2007/0002—Head or parts thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
- A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
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Abstract
Description
Translated fromChinese技术领域technical field
本发明涉及医疗器械领域，具体而言，涉及一种血液降温导管及血液降温设备。The invention relates to the field of medical devices, in particular to a blood cooling catheter and blood cooling equipment.
背景技术Background technique
脑血管疾病高致残率和高死亡率对患者生命质量及安全有严重影响，快速再灌注是缺血性脑血管疾病重要治疗策略，但多数患者将产生脑缺血再灌注损伤，部分患者发展为重症脑损伤，其中，治疗性低温治疗缺血性卒中始于1950s进行的开创性研究，迄今已有上百篇文献证实治疗性低温对缺血性脑卒中动物模型有确切的保护作用。因此，治疗性低温可以针对瀑布式级联病理生理过程的多个环节，全面抑制脑缺血再灌注损伤网络，被认为是最为有效的神经保护措施，实验研究也证实低温对脑缺血模型有确切的神经保护作用。The high disability rate and high mortality rate of cerebrovascular disease have a serious impact on the quality of life and safety of patients. Rapid reperfusion is an important treatment strategy for ischemic cerebrovascular disease. However, most patients will develop cerebral ischemia-reperfusion injury, and some patients will develop For severe brain injury, among them, therapeutic hypothermia in the treatment of ischemic stroke began with pioneering research in the 1950s. So far, hundreds of literatures have confirmed that therapeutic hypothermia has a definite protective effect on ischemic stroke animal models. Therefore, therapeutic hypothermia can comprehensively inhibit the cerebral ischemia-reperfusion injury network by targeting multiple links in the cascade pathophysiological process, and is considered to be the most effective neuroprotective measure. Exact neuroprotective effect.
现有技术中，针对脑内血液温度的降温效果并不理想。In the prior art, the cooling effect on the blood temperature in the brain is not ideal.
发明内容SUMMARY OF THE INVENTION
本发明提供了一种血液降温导管及血液降温设备，其能够提高对脑内血液温度的降温效果。The invention provides a blood cooling catheter and a blood cooling device, which can improve the cooling effect on the blood temperature in the brain.
本发明的实施例可以这样实现：Embodiments of the present invention can be implemented as follows:
本发明的实施例提供了一种血液降温导管，其包括：Embodiments of the present invention provide a blood cooling catheter comprising:
内管，所述内管的内壁限定出第一内流道；an inner tube, the inner wall of which defines a first inner flow channel;
外螺纹管，所述外螺纹管的内壁限定出第二内流道；以及an externally threaded tube, the inner wall of the externally threaded tube defining a second internal flow channel; and
外管，所述外管依次套设于所述内管及所述外螺纹管，所述外管的部分内壁和所述内管的外壁之间限定出外流道，所述外管的另一部分内壁和所述外螺纹管之间限定出螺纹外流道；an outer tube, the outer tube is sleeved on the inner tube and the outer threaded tube in sequence, an outer flow channel is defined between a part of the inner wall of the outer tube and the outer wall of the inner tube, and another part of the outer tube A threaded outer flow channel is defined between the inner wall and the outer threaded pipe;
所述第一内流道、所述第二内流道、所述螺纹外流道以及所述外流道依次连通。The first inner flow channel, the second inner flow channel, the threaded outer flow channel and the outer flow channel are communicated in sequence.
可选地，所述外管包括第一外管以及第二外管，所述第一外管和所述第二外管可拆卸连接；Optionally, the outer tube includes a first outer tube and a second outer tube, and the first outer tube and the second outer tube are detachably connected;
所述第一外管套设于所述内管，所述第二外管套设于所述外螺纹管，所述第一外管的内壁和所述内管的外壁之间限定出外流道，所述第二外管的内壁和所述外螺纹管之间限定出螺纹外流道。The first outer tube is sleeved on the inner tube, the second outer tube is sleeved on the outer threaded tube, and an outer flow channel is defined between the inner wall of the first outer tube and the outer wall of the inner tube , a threaded outer flow channel is defined between the inner wall of the second outer pipe and the outer threaded pipe.
可选地，所述外螺纹管包括管体以及外螺纹凸筋，所述管体的内壁限定出第二内流道，所述外螺纹凸筋设置于所述管体的外壁；Optionally, the externally threaded pipe includes a pipe body and an externally threaded rib, the inner wall of the pipe body defines a second inner flow channel, and the externally threaded rib is disposed on the outer wall of the pipe body;
所述第二外管的内壁抵接于所述外螺纹凸筋远离所述管体外壁的一侧。The inner wall of the second outer tube abuts on the side of the external thread bead away from the outer wall of the tube.
可选地，所述外螺纹管的数目为多个，多个所述管体依次连通，多个所述外螺纹凸筋间隔设置。Optionally, the number of the externally threaded pipes is multiple, the multiple pipe bodies are connected in sequence, and the multiple externally threaded ribs are arranged at intervals.
可选地，所述血液降温导管还包括分隔套管，所述分隔套管套设于相邻所述管体的端部。Optionally, the blood cooling catheter further includes a separation sleeve, and the separation sleeve is sleeved on the end of the adjacent tube body.
可选地，所述血液降温导管还包括回流件，所述回流件设有内流孔道以及与所述内流孔道连通的外流孔，所述管体和所述内流孔道连通，所述外流孔和所述螺纹外流道连通；Optionally, the blood cooling catheter further includes a backflow member, the backflow member is provided with an inner flow hole and an outer flow hole communicated with the inner flow hole, the pipe body is communicated with the inner flow hole, and the outer flow hole is in communication with the inner flow hole. the hole communicates with the outer threaded channel;
所述回流件卡设于所述第二外管远离所述第一外管的端口，以封堵所述第二外管远离所述第一外管的端口。The return element is clamped at the port of the second outer tube away from the first outer tube, so as to block the port of the second outer tube away from the first outer tube.
可选地，所述血液降温导管还包括进出液接头，所述进出液接头同时连接所述外管以及所述内管，所述进出液接头的进液管和所述第一内流道连通，所述进出液接头的出液管和所述外流道连通。Optionally, the blood cooling catheter further comprises a liquid inlet and outlet joint, the liquid inlet and outlet joints are connected to the outer pipe and the inner pipe at the same time, and the liquid inlet pipe of the liquid inlet and outlet joints communicates with the first inner flow channel. , the liquid outlet pipe of the liquid inlet and outlet joint is communicated with the outer flow channel.
可选地，所述血液降温导管还包括抗凝血涂层，所述抗凝血涂层设置于所述外管的外壁。Optionally, the blood cooling catheter further includes an anti-coagulation coating, and the anti-coagulation coating is disposed on the outer wall of the outer tube.
可选地，所述血液降温导管还包括抗菌涂层，所述抗菌涂层设置于所述外管的外壁。Optionally, the blood cooling catheter further includes an antibacterial coating, and the antibacterial coating is disposed on the outer wall of the outer tube.
本发明的实施例还提供了一种血液降温设备，包括循环液泵以及上述的血液降温导管，所述循环液泵的进液端和出液端分别连通所述第一内流道的进液口以及所述外流道的出液口。An embodiment of the present invention also provides a blood cooling device, comprising a circulating liquid pump and the above-mentioned blood cooling conduit, wherein the liquid inlet end and the liquid outlet end of the circulating liquid pump are respectively connected to the liquid inlet of the first inner flow channel port and the liquid outlet of the outer flow channel.
本发明实施例的血液降温导管及血液降温设备的有益效果包括，例如：The beneficial effects of the blood cooling catheter and the blood cooling device according to the embodiments of the present invention include, for example:
本发明的实施例提供了一种血液降温导管，用于对脑内血液进行降温，该血液降温导管包括内管、外螺纹管以及外管，内管的内壁限定出第一内流道，外螺纹管的内壁限定出第二内流道，外管依次套设于内管及外螺纹管，外管的部分内壁和内管的外壁之间限定出外流道，外管的另一部分内壁和外螺纹管之间限定出螺纹外流道，第一内流道、第二内流道、螺纹外流道以及外流道依次连通，将血液降温导管介入于脑内血管中，将冷却液(例如生理盐水)灌注进入第一内流道的进液口后，依次经过第一内流道、第二内流道、螺纹外流道以及外流道，最后从外流道的出液口流出，冷却液经过螺纹外流道时，能够较大程度降低了冷却液的流动速度，进而可以使冷却液和血管内的血液进行更多的热量交换，显著降低了脑内血液的温度，提高了对脑内血液温度的降温效果。An embodiment of the present invention provides a blood cooling catheter for cooling blood in the brain. The blood cooling catheter includes an inner tube, an outer threaded tube and an outer tube. The inner wall of the inner tube defines a first inner flow channel, and the outer tube The inner wall of the threaded tube defines a second inner flow channel, the outer tube is sleeved on the inner tube and the outer threaded tube in turn, an outer flow channel is defined between a part of the inner wall of the outer tube and the outer wall of the inner tube, and another part of the inner wall of the outer tube and the outer A threaded outer flow channel is defined between the threaded pipes, and the first inner flow channel, the second inner flow channel, the threaded outer flow channel and the outer flow channel are connected in sequence, the blood cooling catheter is inserted into the blood vessels in the brain, and the cooling liquid (such as normal saline) After pouring into the liquid inlet of the first inner flow channel, it passes through the first inner flow channel, the second inner flow channel, the outer flow channel of the thread and the outer flow channel in sequence, and finally flows out from the liquid outlet of the outer flow channel, and the coolant passes through the outer flow channel of the screw thread. It can greatly reduce the flow speed of the cooling liquid, and then make more heat exchange between the cooling liquid and the blood in the blood vessels, significantly reduce the temperature of the blood in the brain, and improve the cooling effect of the blood temperature in the brain. .
本发明的实施例还提供了一种血液降温设备，包括循环液泵以及上述的血液降温导管，所述循环液泵的进液端和出液端分别连通所述第一内流道的进液口以及所述外流道的出液口，提高了对脑内血液温度的降温效果。An embodiment of the present invention also provides a blood cooling device, comprising a circulating liquid pump and the above-mentioned blood cooling conduit, wherein the liquid inlet end and the liquid outlet end of the circulating liquid pump are respectively connected to the liquid inlet of the first inner flow channel The mouth and the liquid outlet of the outer flow channel improve the cooling effect on the blood temperature in the brain.
附图说明Description of drawings
为了更清楚地说明本发明实施例的技术方案，下面将对实施例中所需要使用的附图作简单地介绍，应当理解，以下附图仅示出了本发明的某些实施例，因此不应被看作是对范围的限定，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其它相关的附图。In order to illustrate the technical solutions of the embodiments of the present invention more clearly, the following briefly introduces the accompanying drawings used in the embodiments. It should be understood that the following drawings only show some embodiments of the present invention, and therefore do not It should be regarded as a limitation of the scope. For those skilled in the art, other related drawings can also be obtained according to these drawings without any creative effort.
图1为本发明的实施例中提供的血液降温导管的示意图；1 is a schematic diagram of a blood cooling catheter provided in an embodiment of the present invention;
图2为本发明的实施例中提供的血液降温导管的局部剖视图；2 is a partial cross-sectional view of a blood cooling catheter provided in an embodiment of the present invention;
图3为本发明的实施例中提供的血液降温导管的第一局部放大图；3 is a first partial enlarged view of the blood cooling catheter provided in the embodiment of the present invention;
图4为本发明的实施例中提供的血液降温导管的第二局部放大图；4 is a second partial enlarged view of the blood cooling catheter provided in the embodiment of the present invention;
图5为本发明的实施例中提供的外螺纹管的示意图。FIG. 5 is a schematic diagram of an externally threaded pipe provided in an embodiment of the present invention.
图标：1000-血液降温导管；100-内管；101-第一内流道；200-外螺纹管；210-管体；220-外螺纹凸筋；211-第二内流道；300-外管；310-第一外管；311-外流道；320-第二外管；321-螺纹外流道；400-分隔套管；500-回流件；501-内流孔道；502-外流孔；600-进出液接头；610-进液管；620-出液管。Icon: 1000-blood cooling catheter; 100-inner tube; 101-first inner flow channel; 200-external threaded tube; 210-tube body; 220-external threaded rib; 211-second inner flow channel; Tube; 310-first outer tube; 311-outer flow channel; 320-second outer tube; 321-threaded outer flow channel; 400-separating sleeve; 500-return piece; -Inlet and outlet joint; 610-inlet pipe; 620-outlet pipe.
具体实施方式Detailed ways
为使本发明实施例的目的、技术方案和优点更加清楚，下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例是本发明一部分实施例，而不是全部的实施例。通常在此处附图中描述和示出的本发明实施例的组件可以以各种不同的配置来布置和设计。In order to make the purposes, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments These are some embodiments of the present invention, but not all embodiments. The components of the embodiments of the invention generally described and illustrated in the drawings herein may be arranged and designed in a variety of different configurations.
因此，以下对在附图中提供的本发明的实施例的详细描述并非旨在限制要求保护的本发明的范围，而是仅仅表示本发明的选定实施例。基于本发明中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其它实施例，都属于本发明保护的范围。Thus, the following detailed description of the embodiments of the invention provided in the accompanying drawings is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
应注意到：相似的标号和字母在下面的附图中表示类似项，因此，一旦某一项在一个附图中被定义，则在随后的附图中不需要对其进行进一步定义和解释。It should be noted that like numerals and letters refer to like items in the following figures, so once an item is defined in one figure, it does not require further definition and explanation in subsequent figures.
在本发明的描述中，需要说明的是，若出现术语“上”、“下”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，或者是该发明产品使用时惯常摆放的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。In the description of the present invention, it should be noted that, if the terms "upper", "lower", "inner", "outer", etc. appear, the orientation or positional relationship indicated is based on the orientation or positional relationship shown in the drawings, or It is the orientation or positional relationship that the product of the invention is usually placed in use, only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation , so it should not be construed as a limitation of the present invention.
此外，若出现术语“第一”、“第二”等仅用于区分描述，而不能理解为指示或暗示相对重要性。In addition, where the terms "first", "second" and the like appear, they are only used to differentiate the description, and should not be construed as indicating or implying relative importance.
需要说明的是，在不冲突的情况下，本发明的实施例中的特征可以相互结合。It should be noted that the features in the embodiments of the present invention may be combined with each other without conflict.
脑血管疾病高致残率和高死亡率对患者生命质量及安全有严重影响，快速再灌注是缺血性脑血管疾病重要治疗策略，但多数患者将产生脑缺血再灌注损伤，部分患者发展为重症脑损伤，该损伤发生机制为脑部供血中断后，重新开通闭塞血管及恢复大脑血供后的缺血再灌注损伤级联反应如自由基形成，重度炎性反应，神经兴奋性因子产生，神经元细胞线粒体凋亡等进一步造成脑组织损伤。The high disability rate and high mortality rate of cerebrovascular disease have a serious impact on the quality of life and safety of patients. Rapid reperfusion is an important treatment strategy for ischemic cerebrovascular disease. However, most patients will develop cerebral ischemia-reperfusion injury, and some patients will develop It is a severe brain injury. The mechanism of the injury is that after the blood supply to the brain is interrupted, the occluded blood vessels are reopened and the blood supply to the brain is restored. Cascade reactions of ischemia-reperfusion injury such as free radical formation, severe inflammatory response, and production of nerve excitatory factors , neuronal cell mitochondrial apoptosis and other further cause brain tissue damage.
因此，采取有效治疗措施抑制损伤机制，降低损伤程度对患者病情恢复具有重要意义。其中，治疗性低温治疗缺血性卒中始于1950s进行的开创性研究，迄今已有上百篇文献证实治疗性低温对缺血性脑卒中动物模型有确切的保护作用。因此，治疗性低温可以针对瀑布式级联病理生理过程的多个环节，全面抑制脑缺血再灌注损伤网络，被认为是最为有效的神经保护措施，实验研究也证实低温对脑缺血模型有确切的神经保护作用。Therefore, taking effective therapeutic measures to inhibit the injury mechanism and reduce the degree of injury is of great significance for the recovery of the patient's condition. Among them, therapeutic hypothermia in the treatment of ischemic stroke began with pioneering research in the 1950s. So far, hundreds of literatures have confirmed that therapeutic hypothermia has a definite protective effect on animal models of ischemic stroke. Therefore, therapeutic hypothermia can comprehensively inhibit the cerebral ischemia-reperfusion injury network by targeting multiple links in the cascade pathophysiological process, and is considered to be the most effective neuroprotective measure. Exact neuroprotective effect.
近年来，血管内取栓技术的开展使得打通闭塞动脉更早更快，神经组织的缺血再灌注损伤也更早发生，因此对脑组织的低温保护则是迫在眉睫的要求，但在现有技术中，针对脑内血液温度的降温效果并不理想。In recent years, the development of endovascular thrombectomy technology has made the opening of occluded arteries earlier and faster, and the ischemia-reperfusion injury of neural tissue occurs earlier. Therefore, the cryoprotection of brain tissue is an imminent requirement, but in the existing technology , the cooling effect on the blood temperature in the brain is not ideal.
有鉴于此，请参考图1-图5，本实施例提供了一种血液降温导管及血液降温设备可以解决这一问题，接下来将对其进行详细的描述。In view of this, please refer to FIG. 1 to FIG. 5 , this embodiment provides a blood cooling catheter and a blood cooling device to solve this problem, which will be described in detail below.
本发明的实施例提供了一种血液降温设备，可用于对脑内血液进行降温，血液降温设备包括循环液泵以及血液降温导管1000，循环液泵的进液端和出液端分别连通第一内流道101的进液口以及外流道311的出液口，以便于进行冷却液循环流动，在本实施例中，冷却液为生理盐水，其中，血液降温导管1000能够提高对脑内血液温度的降温效果。The embodiment of the present invention provides a blood cooling device, which can be used to cool blood in the brain. The blood cooling device includes a circulating liquid pump and a
具体来说,该血液降温导管1000包括内管100、外螺纹管200以及外管300，内管100的内壁限定出第一内流道101，外螺纹管200的内壁限定出第二内流道211，外管300依次套设于内管100及外螺纹管200，外管300的部分内壁和内管100的外壁之间限定出外流道311，外管300的另一部分内壁和外螺纹管200之间限定出螺纹外流道321，第一内流道101、第二内流道211、螺纹外流道321以及外流道311依次连通，将血液降温导管1000介入于脑内血管中。Specifically, the
启动循环液泵，冷却液灌注进入第一内流道101的进液口后，依次经过第一内流道101、第二内流道211、螺纹外流道321以及外流道311，最后从外流道311的出液口流出，冷却液经过螺纹外流道321时，能够较大程度降低了冷却液的流动速度，进而可以使冷却液和血管内的血液进行更多的热量交换，显著降低了脑内血液的温度，提高了对脑内血液温度的降温效果。The circulating liquid pump is started, and after the cooling liquid is poured into the liquid inlet of the first
其中，外管300包括第一外管310以及第二外管320，第一外管310和第二外管320可拆卸连接，第二外管320远离第一外管310的一端可以为封堵状态，以使冷却液依次流经第二内流道211以及螺纹外流道321，同时，也防止冷却液泄露。The
第一外管310套设于内管100，第二外管320套设于外螺纹管200，第一外管310的内壁和内管100的外壁之间限定出外流道311，第二外管320的内壁和外螺纹管200之间限定出螺纹外流道321。The first
具体来说，在本实施例中，外螺纹管200包括管体210以及外螺纹凸筋220，管体210的内壁限定出第二内流道211，外螺纹凸筋220设置于管体210的外壁，且第二外管320的内壁抵接于外螺纹凸筋220远离管体210外壁的一侧，以使冷却液完全经过螺纹外流道321。Specifically, in this embodiment, the externally threaded
为了提高对脑内血液的冷却效果，外螺纹管200的数目可以为多个，具体来说，外螺纹管200的数目为四个，四个管体210依次连通。In order to improve the cooling effect on the blood in the brain, the number of externally threaded
其中，多个外螺纹凸筋220间隔设置，且血液降温导管1000还包括分隔套管400，分隔套管400套设于相邻管体210的端部，分隔套管400可以对流经螺纹外流道321的冷却液再次阻碍，使冷却液停留时间更长，以增强脑内血液温度的降温效果，同时，外螺纹管200和内管100的连接处也套设有分隔套管400。Wherein, a plurality of external
为了便于拆卸以及组装血液降温导管1000，在本实施例中，血液降温导管1000还包括回流件500，回流件500设有内流孔道501以及与内流孔道501连通的外流孔502，管体210和内流孔道501连通，外流孔502和螺纹外流道321连通，同时，回流件500卡设于第二外管320远离第一外管310的端口，以封堵第二外管320远离第一外管310的端口，冷却液可以依次经过第二内流道211、内流孔道501、外流孔502以及螺纹外流道321。In order to facilitate disassembly and assembly of the
此外，为了方便连接循环液泵的管路，血液降温导管1000还包括进出液接头600，容易理解的是，在本实施例中，进出液接头600采用现有技术中的Y型连接阀，进出液接头600同时连接外管300以及内管100，进出液接头600的进液管610和第一内流道101连通，进出液接头600的出液管620和外流道311连通，冷却液从进液管610进入，最后从出液管620流出。In addition, in order to facilitate the connection of the pipeline of the circulating liquid pump, the
当然了，为了提高血液降温导管1000的抗凝及抗菌性能，血液降温导管1000还包括抗凝血涂层和抗菌涂层，抗凝血涂层设置于外管300的外壁，抗菌涂层设置于外管300的外壁。Of course, in order to improve the anticoagulation and antibacterial properties of the
综上所述，该血液降温导管1000包括内管100、外螺纹管200以及外管300，内管100的内壁限定出第一内流道101，外螺纹管200的内壁限定出第二内流道211，外管300依次套设于内管100及外螺纹管200，外管300的部分内壁和内管100的外壁之间限定出外流道311，外管300的另一部分内壁和外螺纹管200之间限定出螺纹外流道321，第一内流道101、第二内流道211、螺纹外流道321以及外流道311依次连通，将血液降温导管1000介入于脑内血管中，将冷却液(例如生理盐水)灌注进入第一内流道101的进液口后，依次经过第一内流道101、第二内流道211、螺纹外流道321以及外流道311，最后从外流道311的出液口流出，冷却液经过螺纹外流道321时，能够较大程度降低了冷却液的流动速度，进而可以使冷却液和血管内的血液进行更多的热量交换，显著降低了脑内血液的温度，提高了对脑内血液温度的降温效果，同时降低颅内压，改善了脑损伤。To sum up, the
该血液降温设备包括循环液泵以及上述的血液降温导管1000，所述循环液泵的进液端和出液端分别连通所述第一内流道101的进液口以及所述外流道311的出液口，提高了对脑内血液温度的降温效果。The blood cooling device includes a circulating liquid pump and the above-mentioned
以上所述，仅为本发明的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，可轻易想到的变化或替换，都应涵盖在本发明的保护范围之内。因此，本发明的保护范围应以所述权利要求的保护范围为准。The above are only specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art who is familiar with the technical scope disclosed by the present invention can easily think of changes or substitutions. All should be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.
Claims (10)
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