CN115054320A - Conveying system of intracranial thrombus removal support - Google Patents

Abstract

The invention discloses a conveying system of an intracranial thrombus removal support, which comprises a thrombus removal support, wherein a conveying guide wire is connected to the outside of the thrombus removal support, the conveying guide wire comprises a flat section and a grinding section, 1-4 indentation sections are arranged on the grinding section and/or the flat section, one or more guide wire springs are arranged at the far end of the conveying guide wire, the guide wire springs are attached to a connecting end, and a heat-shrinkable tube is sleeved on the outer surfaces of the guide wire springs and the indentation sections. The system has good conveying performance, even if the conveying distance is increased, particularly when the thrombus is conveyed through a far-end tortuous blood vessel, the conveying is still easy and smooth, the safety of the connecting mechanism of the conveying system and the thrombus removal support is higher, the thrombus removal device with a complex structure can be quickly and effectively conveyed to a thrombus removal position, the blood flow recanalization time of a patient thrombus removal blood vessel can be shortened, and the use hand feeling of a doctor on the device can be improved.

Description

Conveying system of intracranial thrombus removal support

Technical Field

The invention relates to the field of medical instruments, in particular to a conveying system of an intracranial thrombus removal support.

Background

Stroke, also commonly known as stroke, is a common and frequently encountered disease worldwide, with the Chinese incidence being the first in the world. Meanwhile, the incidence of stroke is increased year by year, which becomes the first cause of death in China. It has the characteristics of high morbidity, high mortality and high disability rate, and has seriously influenced the life and health of people. At present, the treatment schemes for ischemic stroke mainly comprise drug thrombolysis and interventional instrument thrombus removal. Because the recanalization rate of the drug thrombolysis to the large vessel thrombolysis is low, the risk of drug complications and the like occurs, and meanwhile, the time window of the venous thrombolysis is too short, only 4.5 hours, and only about 5 percent of cerebral apoplexy patients can adopt the thrombolysis treatment. Therefore, compared with thrombolytic therapy, the therapeutic mode of taking thrombus by an interventional instrument has wider applicability, and the rapid development in recent years gradually becomes the main therapeutic mode of acute ischemic stroke, and the therapeutic mode can rapidly recanalize occluded blood vessels, improve the recanalization rate, reduce the incidence rate of drug complications and remarkably improve the prognosis of patients.

The interventional instrument thrombus removal is roughly divided into the following steps according to the functional characteristics: spiral, hairbrush, catching net type, negative pressure suction type and stent type, and the negative pressure suction type and the stent type are mostly used at present. For a bracket type intracranial thrombus removal bracket, how to design a connecting structure of a conveying system and the thrombus removal bracket and ensure the safety and the effectiveness of the bracket, how to improve the safety and the smoothness of the conveying system and convey the thrombus removal bracket to the position of intracranial vascular lesion are also very important, because the use hand feeling of a doctor on an apparatus is improved, and the recanalization time of a patient embolism blood vessel is shortened.

The patent numbers disclosed in china are: CN106725723A invention, "a bracket system for removing embolus", is designed and used a conveying steel cable with a circular outer cross section, which is woven by a plurality of steel wires and shaped, wherein the front end of the conveying steel cable is tightened by a clasp, the clasp is fixed on the tail end of the bracket for removing embolus, and the rear end of the conveying steel cable is tightened by a tightening tail sleeve and has developing property. However, the delivery cable is of constant diameter and does not take into account that as the delivery distance increases, it has greater friction during overbending in tortuous vessels and is difficult to deliver to more distal sites of tortuous vessel embolization.

The patent numbers disclosed in china are: in the invention "segmented thrombus removal device and method for removing thrombus by using the same" of CN106580397A, a segmented structure is adopted, so that flexibility and transportability of the thrombus removal stent are enhanced, the stent can be delivered to a blood vessel with a thin distal end, and the blood vessel thrombus removal stent is connected with a delivery wire in a welding, riveting or pressing manner; the transmission wire is made of flexible metal wire coated with hydrophilic coating on the surface. The technical scheme provides a sectional embolectomy support with good flexibility and conveying performance, but a proper conveying system is not provided, the structure of a conveying wire and the connecting structure of the conveying wire and the embolectomy support are not specifically disclosed, and only a connecting method is provided, so that the safety, effectiveness and integral conveying performance of the apparatus cannot be guaranteed.

The patent numbers disclosed in china are: in the invention of CN108433781A, an intracranial vascular clamping embolectomy device, a delivery guide wire, a protective sheath, a micro-catheter, a guiding catheter, a front Y-valve and a rear Y-valve form a delivery system, wherein the protective sheath is connected with the tail of the micro-catheter through the rear Y-valve, and the front of the micro-catheter is directly connected with the guiding catheter through the front Y-valve.

Therefore, although the flexibility and the transportability of the embolectomy stent are considered in the above patent, the connection safety of the delivery system and the embolectomy device and the transportation performance of the whole instrument cannot be ensured, and the above patent does not disclose a detailed technical scheme for the connection structure of the delivery system and the embolectomy device. Therefore, poor performance of the delivery system for delivering the embolectomy device can reduce the use hand feeling of a doctor for the device and prolong the blood flow recanalization time of the patient for embolizing the blood vessel.

Disclosure of Invention

The invention aims to solve the defects in the prior art and provides a delivery system of an intracranial thrombectomy support.

In order to achieve the purpose, the invention adopts the following technical scheme: a conveying system of an intracranial thrombus removal support comprises a thrombus removal support, wherein a conveying guide wire is connected to the outside of the thrombus removal support;

the conveying guide wire comprises a straight section and a grinding section, and 1-4 sections of indentation sections are arranged on the grinding section and/or the straight section;

the far end of the delivery guide wire is provided with one or more sections of guide wire springs, the guide wire springs are attached to a connecting end to provide far end support for the delivery guide wire, the connecting end comprises a developing ring, and the developing ring is coated on the near end of the thrombus taking support and the outer part of the far end of the delivery guide wire;

and the heat shrink tube is sleeved on the outer surfaces of the wire guide spring and the indentation section.

As a further description of the above technical solution: the diameter of one end of the grinding section, which is closer to the wire guide spring, is smaller, and the diameter of the smallest part of the grinding section is 1/5-1/3 of the diameter of the straight section.

As a further description of the above technical solution: the length of the grinding section is 1/4-1/2 of the length of the delivery guide wire, and the delivery guide wire is made of nickel-titanium alloy materials.

As a further description of the above technical solution: the length of the wire guide spring is 1/20-1/10 of the length of the grinding section, and the wire guide spring is made of platinum iridium, iridium or gold materials.

As a further description of the above technical solution: the delivery guide wire is connected with the embolectomy support in a butt joint mode, a lap joint mode, a winding mode or a perforation mode and the like.

As a further description of the above technical solution: the delivery guide wire and the bolt taking bracket are fixed through welding, dispensing or pressing and holding processes.

As a further description of the above technical solution: the thrombus removal support is of a net pipe structure and formed by connecting a plurality of cells, and the thrombus removal support is made of memory alloy.

As a further description of the above technical solution: the indentation section is made by cutting and pressing processes.

As a further description of the above technical solution: the length of the heat shrinkable tube is matched with the length and the number of the indentation sections.

As a further description of the above technical solution: the connecting structure of the conveying guide wire and the embolectomy support is I-shaped or T-shaped, and a circular hole, a conical hole or a square hole can be formed in the connecting structure.

The invention has the following beneficial effects:

1. the invention is made by cutting and pressing the indentation section of the conveying guide wire, the cross section structure of the indentation section of the conveying guide wire is corrugated, the length of the indentation section can be determined according to the actual requirement, the contact area with the catheter can be reduced when the indentation section enters a tortuous blood vessel, thereby improving the conveying performance, even if the conveying distance is increased, particularly when the indentation section passes through the more remote tortuous blood vessel, the conveying is still easy and smooth, and the conveying performance is good.

2. According to the invention, the delivery guide wire and the thrombus taking support are connected in a butt joint mode, a lap joint mode, a winding mode, a perforation mode and the like, and the connection modes are fixed twice, so that the safety of the connection structure of the delivery guide wire and the intracranial thrombus taking support is improved.

3. According to the invention, the grinding section is arranged at the far end of the delivery guide wire, and the grinding section is softer and has certain toughness, so that the grinding section can enter small blood vessels in the human cranium more conveniently, and the heat shrink tube outside the indentation section is made of a high polymer material with smooth performance, so that the resistance of delivering the embolectomy stent to an embolism area can be reduced, and the grinding section and the heat shrink tube are combined, so that the embolectomy device with a complex structure can be rapidly and effectively delivered to an embolism position.

4. The guide wire spring is arranged at the far end of the delivery guide wire, so that the support can be provided for the delivery guide wire, the guide wire spring has a developing function, and a doctor can more intuitively observe the position of the guide wire during operation, so that the blood flow recanalization time of a patient embolizing blood vessels can be shortened, and the use hand feeling of the doctor on the instrument can be improved.

Drawings

FIG. 1 is a schematic diagram of the overall structure of a delivery system for an intracranial thrombectomy stent according to the present invention;

FIG. 2 is a schematic structural view of a delivery guide wire structure of a delivery system of an intracranial thrombectomy stent provided in the invention;

FIG. 3 is a schematic diagram of an indentation segment of a delivery system for an intracranial thrombectomy stent according to the present invention;

FIG. 4 is a schematic view of the butt joint connection mode of a delivery guide wire and a thrombus removal support of the delivery system for an intracranial thrombus removal support;

FIG. 5 is a schematic view of a delivery guide wire and a embolectomy stent lap joint mode of the delivery system of an intracranial embolectomy stent provided by the invention;

FIG. 6 is a schematic view of a winding connection mode of a delivery guide wire and a thrombus removal support of a delivery system of an intracranial thrombus removal support according to the invention;

FIG. 7 is a schematic view of a delivery guide wire and a puncture hole of a thrombus removal support of the delivery system for an intracranial thrombus removal support;

FIG. 8 is a schematic view of a delivery guide wire and a perforation connection mode of an encephalic embolectomy support delivery system provided by the invention.

Illustration of the drawings:

1. a thrombus taking support; 2. delivering a guide wire; 201. a straight section; 202. grinding the section; 203. an indentation section; 3. a wire guide spring; 4. a connecting end; 401. a developing ring; 5. and (7) heat-shrinkable tubes.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention; the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance, and furthermore, unless otherwise explicitly stated or limited, the terms "mounted," "connected," and "connected" are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Referring to fig. 1-3, one embodiment of the present invention is provided: a conveying system of an intracranial thrombus removal support comprises athrombus removal support 1, wherein thethrombus removal support 1 has the characteristic of multi-section developing, and a conveyingguide wire 2 is connected to the outside of thethrombus removal support 1;

thethrombus extraction support 1 can be a multi-section thrombus extraction support, a double-layer thrombus extraction support, a thrombus extraction support with a longer specification or other thrombus extraction devices with complex structures;

the conveyingguide wire 2 comprises aflat section 201 and a grindingsection 202, 1-4 sections ofindentation sections 203 are arranged on the grindingsection 202 and/or theflat section 201, the grindingsection 202 at the far end can be replaced by theflat section 201 at the far end, and the number of theflat sections 201 can be determined according to the specific design;

the grindingsection 202 is softer and has certain toughness, so that the grinding section can enter tiny blood vessels in the human cranium more conveniently.

Theindentation section 203 can also be replaced by a ground winding wire, so that the friction force during overbending can be reduced;

the far end of thedelivery guide wire 2 is provided with one or more sections of guide wire springs 3, the guide wire springs 3 are attached to the connecting end 4 to provide far end support for thedelivery guide wire 2, the connecting end 4 comprises a developing ring 401, and the developing ring 401 is coated outside the near end of thethrombus removal support 1 and the far end of thedelivery guide wire 2;

the heatshrinkable tube 5 is sleeved on the outer surfaces of thewire spring 3 and theindentation section 203, and the heatshrinkable tube 5 is made of a high polymer material with smooth performance, so that pushing resistance can be reduced when thethrombus removing support 1 is conveyed.

Further, the diameter of the grindingsection 203 at the end closer to thewire spring 3 is smaller, and the diameter of the grindingsection 203 at the smallest position is 1/5-1/3 of the diameter of thestraight section 201.

Further, the length of the grindingsection 202 is 1/4-1/2 of the length of thedelivery guide wire 2, and thedelivery guide wire 2 is made of nickel titanium alloy or other shape memory materials.

Further, the length of theguide wire spring 3 is 1/20-1/10 of the length of the grindingsection 202, and theguide wire spring 3 is made of materials such as platinum iridium, gold or medical stainless steel, and the materials can be visible under X-rays.

Further, the conveyingguide wire 2 is connected with theembolectomy support 1 in a butt joint mode, a lap joint mode, a winding mode or a perforation mode and the like, and anindentation section 203 can be arranged at the bending position of the far end of the conveyingguide wire 2, so that the developing ring 401 can be pressed, held and tightened conveniently.

Referring to fig. 4, an embodiment of the present invention is provided: the butt joint connection mode means that the far end of thedelivery guide wire 2 is aligned with the near end of thethrombus removal support 1, the delivery guide wire and the thrombus removal support are positioned on the same horizontal line, a developing ring 401 can be assembled after welding, and the developing ring 401 is fixed again through pressing and holding or dispensing;

referring to fig. 5, an embodiment of the present invention is provided: the lap joint connection mode means that the far end of thedelivery guide wire 2 is lapped on the near end of the intracranialthrombus removal support 1, and the delivery guide wire is fixed by welding, is fixed by pressing after being assembled with the developing ring 401 or is fixed by dispensing after being pressed;

referring to fig. 6, an embodiment of the present invention provides: the winding connection mode means that the structure of the near end of the intracranialthrombus removal support 1 is designed into an I shape, the far end of the conveyingguide wire 2 is wound on the near end of the intracranialthrombus removal support 1 and is fixed by welding, a developing ring 401 is assembled and then is pressed and held or glued for fixing again, the number of winding turns is 1-10, and the winding connection mode can be determined according to the structure of the near end of thethrombus removal support 1;

referring to fig. 7-8, one embodiment of the present invention provides: the perforation connection mode means that the structure of the near end of theintracranial thrombectomy support 1 is designed to be T-shaped, a round hole, a tapered hole or a square hole is arranged on the T-shaped, the hole and the T-shaped are concentric and centrally arranged, the far end of the conveyingguide wire 2 penetrates through the perforation and then is arranged in the developing ring 401, then the developing ring 401 is fixed by pressing and holding or dispensing after pressing and holding, or is fixed by welding after perforation and then is assembled with the developing ring 401 and then is fixed by pressing and holding or dispensing again, and the diameter of the farthest end of the conveyingguide wire 2 is smaller than the diameter or the width of the hole.

According to the technical scheme, the connection part of the connecting end 4 is fixed twice, so that the overall conveying safety of the instrument is improved.

Further, thedelivery guide wire 2 and thethrombus removal support 1 are fixed through welding, dispensing or pressing and holding processes.

Further, thethrombus taking support 1 is of a net pipe structure and is formed by connecting a plurality of cells, and the material of thethrombus taking support 1 is memory alloy.

Further, theindentation section 203 is made by a cutting and crimping process.

Further, the length of the heatshrinkable tube 5 is adapted to the length and number of theindentation sections 203.

Further, the connecting structure of thedelivery guide wire 2 and theembolectomy support 1 is I-shaped or T-shaped, and a circular hole, a conical hole or a square hole can be formed in the connecting structure.

The working principle is as follows: in the conveying system of the intracranial thrombus removal support, the far-end grinding section 202, the indentation section 203 of the conveying guide wire 1, the guide wire spring 3 and the heat-shrinkable tube 5 are arranged on the conveying guide wire 2, so that the contact surface of the conveying guide wire 2 and a catheter can be reduced when the intracranial thrombus removal support 1 is conveyed to a tortuous blood vessel or a blood vessel with a larger distance and a smaller diameter, the resilience of the conveying guide wire during bending is properly weakened, and the conveying friction force is reduced, so that the conveying performance of the intracranial thrombus removal support 1 is improved, the blood flow recanalization time of a patient embolism blood vessel can be shortened, and the use hand feeling of a doctor on an instrument is improved; different connecting structures of the delivery guide wire 2 and the intracranial thrombus removal support 1 are arranged, such as butt joint, lap joint, winding and perforation, and the connecting structures improve the safety of the overall delivery of the instrument through two times of fixation; in addition, the distal end of the delivery guide wire 2 is provided with the grinding section 202, and the grinding section 202 is softer and has certain toughness, so the delivery guide wire can more conveniently enter small blood vessels in the intracranial of a human body, and the heat shrinkable tube 5 outside the indentation section 203 is made of a high polymer material with smooth performance, so the resistance of delivering the embolectomy stent 1 to an embolization area can be reduced, and the embolectomy device with a complex structure can be more quickly and effectively delivered to an embolization position by combining the grinding section 202 and the heat shrinkable tube 5 with excellent delivery performance provided by the invention.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.

Claims (10)

1. A conveying system of an intracranial thrombectomy support comprises a thrombectomy support (1), and is characterized in that: the outside of the thrombus taking support (1) is connected with a conveying guide wire (2);

the conveying guide wire (2) comprises a straight section (201) and a grinding section (202), and 1-4 sections of indentation sections (203) are arranged on the grinding section (202) and/or the straight section (201);

one or more guide wire springs (3) are arranged at the far end of the delivery guide wire (2), the guide wire springs (3) are attached to a connecting end (4) to provide far-end support for the delivery guide wire (2), the connecting end (4) comprises a developing ring (401), and the developing ring (401) is coated outside the near end of the thrombus removing support (1) and the far end of the delivery guide wire (2);

and the heat shrink tube (5) is sleeved on the outer surfaces of the wire guide spring (3) and the indentation section (203).

2. The delivery system for an intracranial thrombectomy stent according to claim 1, wherein: the diameter of one end of the grinding section (203) which is closer to the wire guide spring (3) is smaller, and the diameter of the smallest part of the grinding section (203) is 1/5-1/3 of the diameter of the straight section (201).

3. The delivery system for an intracranial thrombectomy stent according to claim 1, wherein: the length of the grinding section (202) is 1/4-1/2 of the length of the delivery guide wire (2), and the delivery guide wire (2) is made of nickel-titanium alloy material.

4. The delivery system for an intracranial thrombectomy stent according to claim 1, wherein: the length of the wire guide spring (3) is 1/20-1/10 of the length of the grinding section (202), and the wire guide spring (3) is made of platinum and iridium or an iridium material.

5. The delivery system for an intracranial thrombectomy stent according to claim 1, wherein: the delivery guide wire (2) is connected with the embolectomy support (1) in a butt joint mode, a lap joint mode, a winding mode or a perforation mode and the like.

6. The delivery system for an intracranial thrombectomy stent according to claim 1, wherein: the delivery guide wire (2) and the bolt taking bracket (1) are fixed through welding, dispensing or pressing and holding processes.

7. The delivery system for an intracranial thrombectomy stent according to claim 1, wherein: the thrombus removal support (1) is of a net pipe structure and formed by connecting a plurality of cells, and the thrombus removal support (1) is made of memory alloy.

8. The delivery system for an intracranial thrombectomy stent according to claim 1, wherein: the indentation section (203) is made by cutting and pressing processes.

9. The delivery system for an intracranial thrombectomy stent according to claim 1, wherein: the length of the heat shrinkable tube (5) is matched with the length and the number of the indentation sections (203).

10. The delivery system for an intracranial thrombectomy stent according to claim 1, wherein: the connecting structure of the conveying guide wire (2) and the embolectomy support (1) is I-shaped or T-shaped, and a circular hole, a conical hole or a square hole can be formed in the connecting structure.

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