CN114948060B - Device for inhibiting expansion or rupture of aneurysm - Google Patents

Abstract

The invention discloses an arterial hemangioma expansion or rupture inhibiting device, which comprises an implant, a delivery guide wire and an introducing sheath, wherein the implant and the delivery guide wire are pre-arranged in the introducing sheath, the implant is connected with the delivery guide wire, and one end of the delivery guide wire extends to the outside of the introducing sheath; wherein, the one end of implant is closed end, and its other end is open end, and the implant gets into in the aneurysm and closed end and the laminating of aneurysm wall of aneurysm of artery under the promotion of conveying the wire. The purpose of the aneurysm expansion or rupture inhibiting device is to solve the problem of how to prevent the risk of continued growth or rupture of the aneurysm.

Description

Device for inhibiting expansion or rupture of aneurysm

Technical Field

The invention belongs to the technical field of medical instruments, and particularly relates to an aneurysm expansion or rupture inhibiting device.

Background

Medically, aneurysms of arteries, which are due to lesions or lesions of the walls of the arteries, form a manifestation of localized or diffuse dilatation or bulging of the walls of the arteries, and rupture of the aneurysm can lead to hemorrhagic stroke and even sudden death. The current treatment means of the arterial hemangioma mainly comprise: (1) craniotomy: clamping with an aneurysm clip; (2) intraaneurysmal embolization of aneurysms: spring rings, stent + spring rings, braided bodies (e.g., CN 104918565B); (3) reconstruction of blood vessels of parent arteries: a blood flow directing device.

The starting points of the above aneurysm treatment means are to eliminate aneurysm, prevent blood from continuously flowing into and out of the aneurysm, and prevent the aneurysm from rupturing, thereby achieving the purpose of imagewise healing. However, the formation of an aneurysm is not usually the result in a short time, and when the aneurysm is detected, the hemodynamics of the whole parent blood vessel and its branches have been changed to eliminate the aneurysm, which is the existing treatment means, usually the hemodynamics of the parent blood vessel is changed instantly, and after the aneurysm is clamped, embolized or reconstructed, the blood will not flow into the aneurysm any more, and will flow directly to the distal blood vessel, which will instantly bear larger blood impulse, thus leading to the bleeding of the distal blood vessel.

Meanwhile, intratumoral embolization treatment, represented by a coil, usually results in recurrence of the aneurysm due to insufficient embolization or displacement of thrombus change in the aneurysm; vascular reconstruction, typically a blood flow guide, results in delayed rupture of an arterial aneurysm due to non-adherence of the device, weakening of the ability of blood to flow out of the aneurysm, and the like.

In view of the above, the present inventors provide an aneurysm expansion or rupture suppression device.

Disclosure of Invention

Technical problem to be solved

The invention aims to solve the technical problem of reducing the expansion or rupture risk of the aneurysm of the artery.

(II) technical scheme

The invention provides an aneurysm expansion or rupture inhibiting device, which comprises an implant, a delivery guide wire and an introducing sheath, wherein the implant is connected with the delivery guide wire; wherein,

one end of the implant is a closed end, the other end of the implant is an open end, the implant enters the arterial hemangioma under the pushing of the transmission guide wire in the implantation process, and the closed end is attached to the wall of the arterial hemangioma in the state that the implant is implanted into the arterial hemangioma.

Further, the implant is a single-layer woven body of metal wires.

Further, the average metal coverage of the closed end is greater than or equal to 30%.

Further, the open end is provided with a plurality of logo developing layers.

Further, the implant is a metal wire double-layer braid comprising an outer braid layer and an inner braid layer, and a port of a closed end of the outer braid layer and/or the inner braid layer is concave.

Further, an inner wall portion of the outer braid layer is attached to an outer wall of the inner braid layer.

Further, the implant comprises a metal wire weaving body and a cutting piece, the open end of the metal wire weaving body is connected with the cutting piece, the metal wire weaving body is used for being attached to the tumor wall of the aneurysm, and the cutting piece is used for being attached to the blood vessel wall.

Further, the edge part of the cutting piece is provided with a plurality of mark development layers.

Furthermore, a plurality of mark developing layers are arranged at the joint of the metal wire woven body and the cutting piece.

Further, an end of the delivery wire proximate the implant is a flexible end.

(III) advantageous effects

The device for inhibiting the expansion or rupture of the arterial hemangioma is coexisted with the arterial hemangioma and aims to strengthen the wall of the aneurysm, and because the implant is added, namely the reinforcing steel bars are added into the concrete, the risk of the continuous expansion or rupture of the arterial blood vessel is reduced or completely eliminated; or after the implant is implanted, the part of the implant which is not contacted with the tumor wall of the aneurysm forms thrombus, simultaneously, endothelium climbs along the implant, and finally, the shape of the aneurysm is consistent with that of the implant, and the aneurysm cannot grow or break.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments of the present invention will be briefly described below, and it is obvious that the drawings described below are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

FIG. 1 is a schematic structural view of an implant in an aneurysm dilation or rupture suppression device according to an embodiment of the present invention;

FIG. 2 is a schematic structural view of an implant in another device for inhibiting the dilation or rupture of an aneurysm, according to an embodiment of the invention;

FIG. 3 is a schematic structural view of an aneurysm dilation or rupture prevention device according to an embodiment of the present invention;

fig. 4 is a schematic structural view of another device for inhibiting dilation or rupture of an aneurysm, according to an embodiment of the present invention.

In the figure:

1-an implant; 101-an outer braid layer; 102-an inner braid layer; 2-a delivery wire; 201-a flexible end; 202-push block; 203-recycling blocks; 3-introducing a sheath; 4-marking the development layer; 100-vessel wall; 200-aneurysm.

Detailed Description

The embodiments of the present invention will be described in further detail with reference to the drawings and examples. The following detailed description of the embodiments and the accompanying drawings are provided to illustrate the principles of the invention and are not intended to limit the scope of the invention, i.e., the invention is not limited to the embodiments described, but covers any modifications, alterations, and improvements in the parts, components, and connections without departing from the spirit of the invention.

In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "back", and the like refer to orientations or positional relationships based on orientations or positional relationships shown in the drawings, or orientations or positional relationships conventionally used in the product of the present invention, or orientations or positional relationships conventionally understood by those skilled in the art, which are used for convenience of description and simplification of the description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.

In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed" and "mounted" are to be construed broadly, e.g., as being fixedly attached, detachably attached, or integrally attached; may be directly connected or indirectly connected through an intermediate. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to the embodiments with reference to the attached drawings.

In the description, it should be understood that the terms "distal" and "proximal" in the context should be understood as meaning the sides that are distant from the operator and the sides that are close to the operator, viewed from the direction of the operator.

Fig. 3 is a schematic structural view of an aneurysm expansion or rupture suppressing device according to an embodiment of the present invention, including animplant 1, adelivery guide wire 2, and anintroducer sheath 3, wherein theimplant 1 and thedelivery guide wire 2 are connected, theimplant 1 and thedelivery guide wire 2 are preloaded in theintroducer sheath 3, and one end of thedelivery guide wire 2 extends to the outside of theintroducer sheath 3; one end of theimplant 1 is a closed end, the other end of the implant is an open end, theimplant 1 enters the arterial hemangioma under the push of thetransmission guide wire 2 in the implantation process, and the closed end is attached to the wall of thearterial hemangioma 200 in the state that the implant is implanted into the arterial hemangioma.

In the above embodiment, the closed end is completely closed in an arc shape by a metal ring (e.g., development marker); or can be completely closed into an arc shape by connecting the knitting yarns together; the braided wires at the open ends are connected in pairs.

Theimplant 1 and thedelivery wire 2 are crimped together into theintroducer sheath 3. In use, theintroducer sheath 3 is mated to the microcatheter and thedelivery wire 2 is advanced, and theimplant 1 and thedelivery wire 2 are advanced together into the microcatheter to release theimplant 1. Thetransmission guide wire 2 comprises a guide wire body, a pushingblock 202 and a recoveringblock 203, wherein the pushingblock 202 and the recoveringblock 203 are arranged on the guide wire body in a penetrating mode, the pushingblock 202 is located at the near end of the guide wire body, the recoveringblock 203 is located at the far end of the guide wire body, the far end of the introducingsheath 3 is in butt joint with the micro catheter, thetransmission guide wire 2 is pushed forwards to drive theimplant 1 to enter the micro catheter, meanwhile, the recoveringblock 203 generates forward driving force for theimplant 1, the wall of the introducingsheath 3 generates backward resistance for theimplant 1, but the driving force is larger than the resistance, so that theimplant 1 is pushed into the micro catheter by the recoveringblock 203, and in order to prevent the driving force from being smaller than the resistance, the pushingblock 202 is arranged outside the near end of the introducingsheath 3; while thedelivery wire 2 may be withdrawn directly when it is desired to withdraw theintroducer sheath 3.

As an alternative embodiment, as shown in FIG. 1, theimplant 1 is a single layer woven body of wire. Wherein, the metal wire single-layer braiding body fully laminates with 200 tumor walls of the arterial hemangioma, and when blood flow impacts the 200 tumor walls of the arterial hemangioma, the resistance of the tumor walls is strengthened.

As an alternative embodiment, the average metal coverage of the closed end is greater than or equal to 30%. The metal coverage rate of the part, in the blood vessel wall, of theimplant 1 is smaller than or equal to that of the part, in the arterial hemangioma, of theimplant 1, the higher the metal coverage rate in the arterial hemangioma is, the better the supporting effect on the tumor wall of thearterial hemangioma 200 is, the sensitivity of the blood vessel can be influenced by the contact area with theblood vessel wall 100, and therefore, the smaller the coverage rate is, the better the effect is.

As an alternative embodiment, the open end is provided with a plurality of logo developing layers 4. The mark developing layer 4 is provided to position and mark the position thereof.

As an alternative embodiment, as shown in fig. 2, theimplant 1 is a metal wire double braid comprising anouter braid layer 101 and aninner braid layer 102, the port of the closed end of theouter braid layer 101 and/or theinner braid layer 102 being concave. The arrangement of the concave port can avoid the sharp point of theimplant 1 from damaging the wall of thearterial hemangioma 200.

Specifically, the metal coverage of the closed end of theouter braid layer 101 is equal to or greater than 20%, and the metal coverage of the closed end of theinner braid layer 102 is equal to or greater than 15%.

As an alternative embodiment, the inner wall portion of theouter braid layer 101 is attached to the outer wall of theinner braid layer 102. In particular, theouter braid layer 101 in conformity with theinner braid layer 102 ensures a more stable support of theimplant 1 against the wall of theaneurysm 200.

As an alternative embodiment, theimplant 1 comprises a woven body of metal wires, the open ends of which are connected to a cutting member for engaging the tumor wall of theaneurysm 200 and a cutting member for engaging thevessel wall 100.

Compared with a metal wire knitted body, the combined form of the metal wire knitted body and the cutting piece can ensure that the metal wire knitted body is fully attached to the aneurysm wall of theaneurysm 200 and simultaneously increase the displacement resistance; the metal wire is used for weaving, so that the smooth transition of the tumor neck can be realized, and the risks of thrombosis and intimal hyperplasia are reduced.

As an alternative embodiment, the edge portion of the cutter is provided with a plurality of logo developing layers 4. The mark developing layer 4 is provided to position and mark the edge of the cutting member.

As an alternative embodiment, the junction of the woven body of metal wires and the cutting member is provided with a plurality of logo-developing layers 4. The mark developing layer 4 is provided to position and mark the joint.

As an alternative embodiment, as shown in fig. 3, the end of thedelivery wire 2 near theimplant 1 is a flexible end. Wherein, the implantation in-process, the gentle section of distal end can massageimplant 1 because longer, makes its laminating to the tumor wall ofaneurysm 200 better, and the laminating is better, and the more difficult aversion is, and the protection to the tumor wall is better simultaneously, can not appear delaying the fracture. The flexible end may be J-shaped, coiled spring-shaped.

On the other hand, as shown in fig. 4, for a more distally locatedaneurysm 200, the distal-free soft segment is more flexible and easier to locate.

It should be clear that the embodiments in this specification are described in a progressive manner, and the same or similar parts in the embodiments are referred to each other, and each embodiment focuses on the differences from the other embodiments. The present invention is not limited to the specific steps and structures described above and shown in the drawings. Also, a detailed description of known process techniques is omitted herein for the sake of brevity.

The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several modifications and variations can be made without departing from the technical principle of the present invention, and these modifications and variations should also be regarded as the protection scope of the present invention.

Claims (10)

1. An aneurysm expansion or rupture suppression device comprising an implant (1), a delivery wire (2), and an introducer sheath (3), the implant (1) and the delivery wire (2) being connected, the implant (1) and the delivery wire (2) being pre-assembled to the introducer sheath (3), one end of the delivery wire (2) extending outside the introducer sheath (3); wherein,

one end of the implant (1) is a closed end, the other end of the implant is an open end, the implant (1) enters the aneurysm under the pushing of the transmission guide wire (2) in the implantation process, and the closed end is attached to the aneurysm wall of the aneurysm (200) in the state that the implant is implanted into the aneurysm.

2. The aneurysm expansion or rupture suppression device according to claim 1, wherein the implant (1) is a single layer woven body of wire.

3. The aneurysm dilation or rupture suppression device of claim 2, wherein the average metal coverage of the closed end is 30% or greater.

4. The aneurysm expansion or rupture suppression device according to claim 1, wherein the open end is provided with a plurality of marker visualization layers (4).

5. The aneurysm expansion or rupture suppression device according to claim 1, wherein the implant (1) is a wire double braid comprising an outer braid layer (101) and an inner braid layer (102), and a port of a closed end of the outer braid layer (101) and/or the inner braid layer (102) is concave.

6. The aneurysm expansion or rupture suppression device according to claim 5, wherein an inner wall portion of the outer braid layer (101) conforms to an outer wall of the inner braid layer (102).

7. The aneurysm expansion or rupture suppression device according to claim 1, wherein the implant (1) comprises a woven body of metal wires and a cutting member, the open end of the woven body of metal wires being connected to the cutting member, the woven body of metal wires being configured to conform to the aneurysm wall of the aneurysm (200), the cutting member being configured to conform to the vessel wall (100).

8. The aneurysm expansion or rupture suppression device according to claim 7, wherein the edge portion of the cutting member is provided with a plurality of marker development layers (4).

9. The device for inhibiting the dilatation or rupture of an arterial aneurysm according to claim 7 or 8, wherein a plurality of marker visualization layers (4) are provided at the junction of said woven body of metal wires and said cutting member.

10. The aneurysm expansion or rupture suppression device according to claim 1, wherein an end of the delivery wire (2) near the implant (1) is a flexible end (201).

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