CN114594208A - Real-time detection device for virus spread to epidemic disease in air environment - Google Patents

Abstract

The invention provides a real-time detection device for viruses propagated by epidemic diseases in an air environment, which comprises an ambient air sampler, a disposable air sample cracker, a disposable virus antigen reactor, a virus antigen reactor physical state change detector, an MCU (microprogrammed control Unit) and a peripheral circuit for device control, a communication circuit for communication, a video device for real-time portrait acquisition and the like. And when the virus detection value reaches a detection alarm threshold value, an alarm is started. The device can be respectively arranged in places where people flow or people are closed, so that the searching and controlling timeliness of epidemic virus carrying people is greatly improved.

Description

Real-time detection device for virus spread to epidemic disease in air environment

Technical Field

The invention relates to the field of epidemiological epidemic prevention detection and control caused by viruses, in particular to a real-time detection device for viruses spread to epidemic diseases in an air environment.

Background

The epidemic disease caused by virus is a common epidemic disease, particularly the epidemic pneumonia or other inflammations caused by the novel coronavirus which is troubling people in daily life at present cause considerable serious cases or death cases, and further cause panic or inconvenience in life of people. At present, the generally effective method adopted in China and the world is to carry out the examination and detection of all people aiming at the characteristic nucleic acid of the virus in a large scale, or carry out the nucleic acid detection and examine the possible contact personnel after the infected personnel have diseases, thereby effectively controlling the infection route at least in China. However, this method has a significant disadvantage of a delay in case detection. When nucleic acids are detected positive, the virus carrier may have been present in a multiple environment and cause other infections. In particular, if a person who does not perform nucleic acid screening as required is present, the nucleic acid screening method is not effective. As a supplement to the deficiency of the nucleic acid detection method, once the method is implemented, the method can be deployed and controlled in places with dense people flow or frequent exits, such as markets, airports, stations, offices, even cell entrances and the like, and can also be used as a large-scale nucleic acid detection pre-detection method.

The invention aims to fill the blank, thereby providing another effective method for human fighting against epidemic diseases caused by viruses.

Disclosure of Invention

The invention aims to provide a real-time detection device for viruses spread by epidemic diseases in an air environment.

The technical scheme adopted by the invention for solving the technical problem is as follows:

1. the invention relates to a real-time detection device for virus spread by convection in air environment, which is characterized by comprising an ambient air sampler, a disposable air sample cracker, a disposable virus antigen reactor, a virus antigen reactor physical state change detector, a micromotor for air sampling, an MCU (micro control unit) and a peripheral circuit for device control, a communication circuit for communication, a video device for real-time portrait acquisition and the like.

2. The air sampler as claimed in claim 1 comprises an air inlet in contact with air, an internal air channel for adjusting the intensity of air flow, a micro-motor and a fan for extracting an air sample, a one-way valve for controlling the internal pressure of the sampler, and a sample air storage container, wherein the sample air storage container is connected with the air sample cracker through the one-way valve. When the air storage container reaches the set pressure, the inlet one-way valve of the air storage container is closed, the outlet one-way valve is opened at the same time, and the air sample in the air storage container is injected into the air sample cracker.

3. The disposable air sample cracker of claim 1, in which one end of the air sampler is connected via a one-way valve inside the device and the other end of the air sampler is connected via a one-way valve inside the device to the disposable viral antigen reactor. The disposable air sample cracker contains air sample virus antigen detection cracking liquid which is loaded in advance, and carries out cracking reaction on the air sample under set conditions. When the cracking reaction is completed, the one-way valve in the device is opened, and the cracked air sample is fed into the disposable viral antigen reactor under the action of gas pressure.

4. The disposable viral antigen reactor of claim 1 wherein one end is connected to the disposable air sample cracker through a one-way valve in the device and is connected to the antigen reactor physical status sensing probe by non-direct contact. The virus antigen reactor contains virus antigen preset on medium carrier capable of changing physical state, after the cracked air sample lysate is fed into the disposable virus antigen reactor, the air sample and virus antigen are made to produce immune reaction, and because the immune reaction is specific reaction to virus, no false alarm will occur when the air sample contains no detected virus. When the air sample contains the detected virus, the generated antigen immune reaction can cause the physical state change of the antigen carrier medium (the physical state change comprises but is not limited to the color and the resistance of the antigen medium carrier in the virus antigen reactor, and the like), the change can be received by the physical state change detector sensing probe of the virus antigen reactor which is not directly contacted with the virus antigen reactor and is transmitted to the central control MCU (microprocessor) by the probe, and when the change reaches a set threshold value, the MCU (microprocessor) is triggered to send out detection warning and other processing actions.

5. An MCU (microprocessor) and peripheral circuitry controlled by the apparatus of claim 1, wherein the following functions are included but not limited to:

opening and closing each one-way valve according to the program setting;

pushing the disposable air sample cracker and the disposable viral antigen reactor to automatically replace a new cracker and a new reactor according to the program setting;

receiving sensing probe data and judging according to a program;

self-cleaning the internal pipeline according to program control;

sending a sample detection virus detection warning and virus concentration data set according to a program to a control system center;

sending the using state data of the disposable cracker and the disposable reactor to a control system center and providing warning needed to be supplemented;

providing real-time video information when the virus detection exceeds a threshold value to a deployment control system center;

providing the abnormal information of the detection device to a control system center;

6. the communication circuit of claim 1, further comprising a communication device integrated with the peripheral circuit, the communication device being capable of communicating with the administration system center via wired or wireless communication.

7. The portrait acquisition system of claim 1, comprising a 24-hour video capture recording function within range of the detection device and a programmed time period during which a virus detection exceeds a threshold. And acquiring the portrait within a time period set by a program when the threshold value is reached.

FIG. 1 is a schematic diagram of a detection apparatus, which is illustrated as follows:

1 is air sampler, 2 is disposable air sample cracker, 3 is disposable virus antigen reactor, 4 is virus antigen reactor physical state change detector, 5 is control MCU and peripheral circuit, 6 is communication module, 7 is video module, 8 to 10 are controllable one-way valve, 11 is outside air

Detailed Description

1. Referring to the drawings, whenexternal air 11 is sucked into the air sampler 1 through a micro-motor and a fan in the air sampler 1, the process is controlled by a check valve 1 controlled by a micro-controller unit (microprocessor) and opens a check valve 8 at set time intervals, and the sucked air is subjected to speed reduction regulation in an internal air duct after an internal fan in the air sampler 1 and is sent to an air sample reservoir in the air sampler 1 for temporary storage. The sample reservoir contains a solution of pre-filled activators, dispersants, etc. for subsequent sample lysis. When the system reaches the set sampling time, the controlled one-way valve 9 is opened and the air sample solution is pushed into figure 2 (disposable air sample cracker) using the internal pressure.

2. Two ends of a 2 (disposable air sample cracker) in the attached figure comprise sealing plugs which are made of flexible materials such as silica gel and fall in a single direction, and when the 2 is added into the device, the sealing plugs are pushed into the disposable air sample cracker under the action of the top heads preset in the front end pipeline and the rear end pipeline, so that the inlet and the outlet of the liquid phase flow of the sample cracker are opened. The disposable air sample cracker is preset with relevant enzyme system and other supplementary liquid for cracking virus sample, and if necessary, the temperature and vibration of the sample cracker are controlled based on the cracking condition. After completion of the lysis reaction within the set lysis time, the controlled one-way valve 10 is opened and the sample lysate is injected 3 (disposable viral antigen reactor) by internal air pressure.

3. In the attached figure 3 (disposable viral antigen reactor) the liquid phase inlet end contains a one-way falling sealing plug made of flexible materials such as silica gel, when 3 is added into the device, the sealing plug is pushed to fall into the disposable viral antigen reactor under the action of a top head preset in a front end pipeline, so that the liquid phase inlet of the reactor is opened. The disposablevirus antigen reactor 3 comprises a preset sample liquid container, a sample liquid flowing substrate and other devices. The sample liquid is driven by capillary action, electrophoresis action or mobile phase driving action, etc. to flow from one end of the matrix to the other end of the matrix according to a set flow rate on the flowing matrix. The sample liquid flowing matrix is provided with a relevant antigen reaction area of virus to be detected in advance at a certain position, the antibody of the virus to be detected is fixed on the reaction area in advance, after the sample liquid flows to the antigen reaction area, if the sample liquid contains the antigen of specific virus, the sample liquid and the antibody in the antigen reaction area are subjected to immunoreaction, and the reaction can change the conductivity or the color of the antigen reaction area. Whereas if no antigen of a specific virus is contained, the conductivity or color change of the reaction region is within a controlled range. The result of the change in the electric conductivity or color in the antigen reaction region after the completion of the reaction is measured by 4 (reactor physical state change sensor) in the drawing to judge whether or not the virus to be detected is contained in the air sample.

4. The 2 (disposable air sample cracker) and the 3 (disposable viral antigen reactor) are both designed to be disposable, and after each detection is completed, the internal pipeline of the device is automatically replaced and cleaned through a replacement system arranged in the device.

5. Fig. 5 in the drawing is a device control system, and its main components are an MCU (microprocessor) for control and peripheral circuits.

6. Fig. 6 shows a built-in communication module of the device, which is used for communicating with a social virus control center in a wired or wireless manner, including the operation state of the device and the occurrence of virus detection warning.

7. Fig. 7 in the accompanying drawings is a built-in video module of the device, which is used for video acquisition of the device site before and after a virus detection warning occurs, and provides help for effectively finding out virus carrying personnel.

Claims (1)

1. The invention relates to a real-time detection device for viruses spread by convection in an air environment, which is characterized by comprising an ambient air sampler, a disposable air sample cracker, a disposable virus antigen reactor and a virus antigen reactor physical state change detector.

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