Disclosure of Invention
The invention mainly aims to provide a mixing device and a sample analyzer, and aims to provide a mixing device with good mixing effect, which is convenient for placing a reaction container, prevents the positioning accuracy of the reaction container from being affected by lateral pressure when the reaction container is inserted and taken out and clamped, and reduces the noise when the reaction container is taken out and placed.
In order to achieve the above object, the present invention provides a mixing device, including:
the mounting frame is provided with a transverse moving assembly;
The lifting mechanism comprises a base plate and a lifting assembly arranged on the base plate, wherein the base plate is movably arranged on the mounting frame and is connected with the transverse moving assembly, and
The mixing mechanism comprises a base, a driving assembly and a mixing assembly, wherein the base is movably arranged on the base plate and is connected with the lifting assembly, the driving assembly is arranged on the base, the mixing assembly comprises a swinging frame and a container seat, the swinging frame is movably connected with an output shaft of the driving assembly, the container seat is rotatably connected with the swinging frame, the container seat is provided with a containing cavity, and the containing cavity is used for bearing a reaction container;
The base is driven to move in a first direction, the base is driven to move in a second direction, and the first direction and the second direction form an included angle.
In an embodiment, the base is provided with a mounting hole, the driving assembly comprises a driving piece and a crankshaft, the crankshaft comprises a main shaft and an eccentric shaft, one end of the main shaft is rotatably arranged in the mounting hole in a penetrating mode and is connected with the eccentric shaft, the axis of the eccentric shaft is parallel to and is not coincident with the axis of the crankshaft, the eccentric shaft is movably connected with the swing frame, the driving piece comprises a rotating motor, a driven wheel and a driving belt, the rotating motor is arranged on the base, an output shaft of the rotating motor is provided with a driving wheel, the driven wheel is sleeved on the main shaft, and the driving belt is sleeved on the driving wheel and the driven wheel;
the rotary motor drives the driving wheel to rotate, so that the driving belt drives the driven wheel and the crankshaft to rotate.
In one embodiment, the swing frame includes:
The rotating seat is provided with a connecting hole, one end of the eccentric shaft far away from the main shaft is rotatably arranged in the connecting hole in a penetrating way through a bearing piece, and
The support frame is arranged on the rotating seat, the support frame is provided with a swinging groove, and the container seat is arranged in the swinging groove in a swinging way.
In one embodiment, the support frame comprises:
a base arranged on the rotating seat, and
The two support arms are arranged on one side of the base, which is opposite to the rotating seat, at intervals, are oppositely arranged, are matched with the base to form the swinging groove and two through holes communicated with the swinging groove, and are provided with shaft holes;
the outer wall of the container seat is provided with a rotating shaft corresponding to each shaft hole, and the rotating shaft penetrates through the shaft holes in a rotating mode.
In an embodiment, the swing frame further includes an anti-collision rod, and the anti-collision rod is disposed on the rotating seat and corresponds to the through hole;
When the container seat swings around the rotating shaft, one end of the container seat, which is far away from the rotating shaft, extends out of the through hole and is in limiting abutting connection with the anti-collision rod.
In an embodiment, the swing frame further includes an elastic member, one end of the elastic member is connected to the bottom of the container base, and the other end of the elastic member is connected to the base or the bumper bar.
In an embodiment, the two anti-collision bars are respectively arranged on two opposite sides of the base and are respectively arranged corresponding to the two through holes, the two elastic pieces comprise two elastic pieces, one ends of the two elastic pieces are connected with the bottom of the container base, and the other ends of the two elastic pieces are respectively connected with the two anti-collision bars;
And/or the bottom of the container seat is provided with a reset balancing weight, and one end of the elastic piece is connected with the reset balancing weight;
And/or the base is also provided with a chute, the chute extends towards the mounting hole, the swing frame also comprises a guide rod arranged on the rotating seat, and one end of the guide rod, which is far away from the rotating seat, can slidably extend into the chute.
In an embodiment, the lifting assembly comprises a lifting motor, a synchronous wheel and a synchronous belt, wherein the lifting motor is arranged on the substrate, a driving wheel is arranged on an output shaft of the lifting motor, the synchronous wheel is rotatably arranged on the substrate and is spaced from and opposite to the driving wheel, the synchronous belt is sleeved on the driving wheel and the synchronous wheel, and the synchronous belt is fixedly connected with the base, wherein the lifting motor drives the driving wheel to rotate so that the synchronous belt drives the base to lift along the first direction;
And/or the transverse moving assembly comprises a transverse moving motor, a synchronous pulley and a transverse moving belt, wherein the transverse moving motor is arranged on the mounting frame, a driving pulley is arranged on an output shaft of the transverse moving motor, the synchronous pulley is rotatably arranged on the mounting frame and is spaced from and opposite to the driving pulley, the transverse moving belt is sleeved on the driving pulley and the synchronous pulley, and the transverse moving belt is fixedly connected with the substrate, and the transverse moving motor drives the driving pulley to rotate so that the transverse moving belt drives the substrate to transversely move along the second direction.
In an embodiment, the mixing device further comprises a transverse movement detection assembly, the transverse movement detection assembly comprises a mounting plate, a transverse movement optical coupler and a transverse movement blocking piece, the mounting plate is arranged on the mounting frame, the transverse movement optical coupler is arranged on the mounting plate, the transverse movement optical coupler is provided with a detection groove, one end of the transverse movement blocking piece is connected with the substrate, and the other end of the transverse movement blocking piece extends towards the mounting plate;
And/or, the mixing device further comprises a lifting detection assembly, the lifting detection assembly comprises a fixing frame, a lifting optical coupler and a lifting baffle plate, the fixing frame is arranged on the substrate, the lifting optical coupler is arranged on the fixing frame, the lifting optical coupler is provided with a detection port, one end of the lifting baffle plate is connected with the base, and the other end of the lifting baffle plate extends towards the substrate;
and/or, mixing device still includes rotatory detection component, rotatory detection component includes support, rotatory opto-coupler and rotatory separation blade, the support is located the base, rotatory opto-coupler is located the support, rotatory opto-coupler is equipped with the detection breach, the one end of rotatory separation blade connect in drive assembly, the other end of rotatory separation blade orientation detect the breach and extend.
The invention also proposes a sample analyzer comprising:
A main body provided with a disk and a plurality of reaction vessels, the disk being provided with a plurality of mounting openings, each of the reaction vessels being detachably provided at one of the mounting openings, and
The above mixing device is provided on the main body of the apparatus, and the accommodating cavity of the mixing device is opposite to the reaction vessel.
According to the mixing device, the transverse moving assembly is arranged on the mounting frame, the base plate of the lifting mechanism is movably arranged on the mounting frame and connected with the transverse moving assembly, the base of the mixing mechanism is movably arranged on the base plate and connected with the lifting assembly arranged on the base plate, and therefore the transverse moving assembly and the lifting assembly are matched to realize two-dimensional plane movement of the mixing mechanism in the first direction and the second direction; meanwhile, the driving component and the mixing component are arranged on the base of the mixing mechanism, the mixing component is arranged as the swinging frame and the container seat, the swinging frame is movably connected with the driving component arranged on the base, so that the driving component is utilized to provide driving force for the mixing component, the container seat is rotationally connected with the swinging frame, the accommodating cavity of the container seat is utilized to bear the reaction container, when the driving component drives the swinging frame to rotate, the swinging frame can be utilized to provide driving force for the container seat, the swinging of the container seat relative to the swinging frame can be realized by utilizing the swinging frame to rotate, so that the mixing effect of samples in the reaction container in the accommodating cavity is improved, and the mixing device is convenient to realize vertical taking of the reaction container when at rest and enables the swinging angle of the container seat relative to the swinging frame to be increased when mixing, so that the mixing effect of samples in the reaction container in the accommodating cavity is further improved, and further, the container seat and the reaction container simultaneously rotate or swing, so that noise in mixing is effectively reduced, and the mixing component stops driving component and the swinging frame are coaxial, the mixing component is prevented from being inserted into the reaction container when the accommodating cavity is arranged, and the reaction container is prevented from being placed in a coaxial way, and the clamping accuracy is prevented from being placed when the mixing component is positioned and placed in a side direction, the positioning precision and reliability of the taking and placing reaction container are improved.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It should be noted that all directional indicators (such as up, down, left, right, front, and rear are used in the embodiments of the present invention) are merely for explaining the relative positional relationship, movement conditions, and the like between the components in a certain specific posture (as shown in the drawings), and if the specific posture is changed, the directional indicators are changed accordingly.
Meanwhile, the meaning of "and/or" and/or "appearing throughout the text is to include three schemes, taking" a and/or B "as an example, including a scheme, or B scheme, or a scheme that a and B satisfy simultaneously.
Furthermore, descriptions such as those referred to as "first," "second," and the like, are provided for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implying an order of magnitude of the indicated technical features in the present disclosure. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions of the embodiments may be combined with each other, but it is necessary to base that the technical solutions can be realized by those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should be considered to be absent and not within the scope of protection claimed in the present invention.
The blood sample needs to be fully mixed before measurement, otherwise, the measurement result can generate larger deviation. Currently, when an analyzer measures a peripheral blood sample, the sample is mixed uniformly by a finger flick mode manually, and then the mixed sample is put into the analyzer for detection. However, this mixing method greatly limits the number of batch measurement of samples, and increases the burden of manual operation, which is very inconvenient.
In the related art, the butt portion is arranged in the cup seat for placing the reaction cup or the test tube, after the reaction cup or the test tube is inserted into the cup seat, the butt portion can enable the axis of the reaction cup or the test tube and the axis of the cup seat to have a fixed included angle alpha or an eccentric distance d, and the positioning accuracy is subjected to lateral pressure when the test tube is inserted and taken out and clamped, so that the positioning accuracy and the reliability of the taking and placing cup are affected, and the failure that the reaction cup fails to grasp or fails to fall due to insertion is more easily caused. Meanwhile, the included angle between the reaction cup and the axis of the cup seat cannot be too large, the too large test tube cannot be inserted into the cup seat, the test tube is easier to fall off, the included angle is smaller, the test tube is less prone to moving in the horizontal plane and is uniformly mixed, the reaction cup seat is of a rigid structure, and noise is large during uniform mixing.
Based on the above concepts and problems, the present invention proposes a mixing device 700. It can be appreciated that the mixing device 700 is applied to the sample analyzer 900, so as to mix the sample liquid contained in the reaction container 820, so that the sample analyzer 900 can detect the sample liquid contained in the reaction container 820 after being mixed, and the detection accuracy is improved.
Referring to fig. 1 to 11, in an embodiment of the invention, the blending device 700 includes a mounting frame 410, a lifting mechanism and a blending mechanism 100, wherein the mounting frame 410 is provided with a traversing assembly 420, the lifting mechanism includes a base plate 510 and a lifting assembly 520 disposed on the base plate 510, the base plate 510 is movably disposed on the mounting frame 410 and connected with the traversing assembly 420, the blending mechanism 100 includes a base 1, a driving assembly 2 and a blending assembly 3, the base 1 is movably disposed on the base plate 510 and connected with the lifting assembly 520, the driving assembly 2 is disposed on the base 1, the blending assembly 3 includes a swinging frame 31 and a container base 32, the swinging frame 31 is movably connected with an output shaft of the driving assembly 2, the container base 32 is rotatably connected with the swinging frame 31, the container base 32 is provided with a containing cavity 321 for bearing a reaction container 820, wherein the driving assembly 2 drives the swinging frame 31 to rotate, so that the container base 32 swings relative to the swinging frame 31, the lifting assembly 520 drives the base 1 to lift along a first direction, and the traversing assembly 420 drives the base plate 510 to traverse along a second direction, and the first direction forms an included angle with the second direction.
In this embodiment, the mounting frame 410 of the mixing device 700 is used for mounting, fixing and supporting the traversing assembly 420, the lifting mechanism, the mixing mechanism 100, and other components, that is, providing a mounting base for the traversing assembly 420, the lifting mechanism, the mixing mechanism 100, and other components, and simultaneously facilitating the mounting and fixing of the mixing device 700 on the sample analyzer 900. It should be appreciated that the mounting frame 410 may be a mounting plate, a mounting frame, a mounting case, a mounting platform, or the like, and is not limited thereto, as long as it is a structure capable of mounting and fixing the traversing assembly 420, the lifting mechanism, the blending mechanism 100, or the like. Of course, in order to assemble the components such as the traversing assembly 420, the lifting mechanism, and the blending mechanism 100 and to adapt the height, the mounting frame 410 may be formed with a mounting step or a gantry having a height difference, which is not limited herein.
It is to be understood that the traversing assembly 420 is configured to provide a driving force for traversing the lifting mechanism and the blending mechanism 100 along the second direction, and the traversing assembly 420 may be a structure of a driving cylinder, a driving motor and a screw, a structure of a motor and a driving wheel or a driving belt, etc., which is not limited herein. In this embodiment, the lifting assembly 520 and the blending mechanism 100 are integrally mounted on the mounting frame 410 by using the substrate 510 and connected to the traversing assembly 420, so that the traversing assembly 420 drives the substrate 510 to drive the lifting assembly 520 and the blending mechanism 100 to wholly traverse along the second direction.
In this embodiment, the lifting assembly 520 is disposed on the base plate 510, so that the base 1 of the blending mechanism 100 is movably connected with the base plate 510 and is in transmission connection with the lifting assembly 520, so that the lifting assembly 520 is utilized to provide a driving force for lifting the blending mechanism 100 along the first direction, so as to adjust the lifting position of the blending mechanism 100 on the base plate 510. It is understood that the lifting assembly 520 may be a driving cylinder, a structure of a driving motor matching with a screw rod, a structure of a motor matching with a driving wheel or a driving belt, etc., which is not limited herein.
It will be appreciated that the base 1 of the mixing mechanism 100 is used to mount, fix and support the components of the drive assembly 2 and the mixing assembly 3, i.e. the base 1 provides a mounting base for the components of the drive assembly 2 and the mixing assembly 3. It should be understood that the base 1 may be a mounting plate, a mounting rack, a mounting case, a mounting platform, or the like, and is not limited thereto as long as it is a structure capable of mounting and fixing the components such as the driving unit 2 and the blending unit 3. Of course, in order to assemble the components such as the driving unit 2 and the blending unit 3 and to achieve the height adaptation, the base 1 may be formed with a structure such as a mounting step or a gantry having a height difference, which is not limited herein. The mixing mechanism 100 may be mounted and fixed on the mixing device 700 by the base 1, and the base 1 may be integrally provided on the mixing device 700, which is not limited herein.
In this embodiment, the driving component 2 is used for providing driving force for the mixing component 3, so that manpower driving is avoided, manpower is saved, and efficiency is improved. It should be understood that the driving unit 2 may be a driving motor, a rotating motor, a servo motor, a driving cylinder, or the like, and is not limited thereto as long as it can provide driving force to the mixing unit 3.
It can be understood that the mixing assembly 3 is configured as a two-part structure of the swinging frame 31 and the container base 32, and the container base 32 is provided with the accommodating cavity 321, so that the accommodating cavity 321 of the container base 32 is used for accommodating, bearing or spacing and positioning the reaction container 820, and the spacing and spacing placement of the reaction container 820 are realized, meanwhile, the container base 32 is rotationally connected with the swinging frame 31, so that the swinging frame 31 is driven to rotate by the driving assembly 2, so that the container base 32 swings relative to the swinging frame 31, that is, the container base 32 transmits mixing power to the reaction container 820, so that the container base 32 and the reaction container 820 integrally swing relative to the swinging frame 31, and sample liquid in the reaction container 820 is uniformly mixed by swinging.
According to the mixing device 700, the transverse moving assembly 420 is arranged on the mounting frame 410, the base plate 510 of the lifting mechanism is movably arranged on the mounting frame 410 and is connected with the transverse moving assembly 420, the base 1 of the mixing mechanism 100 is movably arranged on the base plate 510 and is connected with the lifting assembly 520 arranged on the base plate 510, and therefore the transverse moving assembly 420 and the lifting assembly 520 are matched to realize two-dimensional plane movement of the mixing mechanism 100 in the first direction and the second direction; meanwhile, the driving component 2 and the mixing component 3 are arranged on the base 1 of the mixing mechanism 100, the mixing component 3 is arranged into the swinging frame 31 and the container seat 32, the swinging frame 31 is movably connected with the driving component 2 arranged on the base 1, so that the driving component 2 is utilized to provide driving force for the mixing component 3, the container seat 32 is rotationally connected with the swinging frame 31, the accommodating cavity 321 of the container seat 32 is utilized to bear the reaction container 820, when the driving component 2 drives the swinging frame 31 to rotate, the swinging frame 31 can be utilized to provide driving force for the container seat 32, the swinging frame 31 can be utilized to rotate to realize the swinging of the container seat 32 relative to the swinging frame 31, the mixing effect of samples placed in the reaction container 820 in the accommodating cavity 321 is improved, and meanwhile, the swinging angle of the container seat 32 relative to the swinging frame 31 is increased, the mixing effect of the samples placed in the reaction container 820 in the accommodating cavity 321 is further improved, the container seat 32 and the reaction container 820 are simultaneously rotated or swung, so that noise during mixing is effectively reduced, and the driving component 2 stops the driving component 100 is stopped, the container seat 32 is arranged coaxially with the reaction container 820, so that the driving component 3 is placed coaxially with the reaction container 820, the positioning accuracy is prevented from being subjected to lateral pressure when the reaction vessel 820 is inserted into and taken out of the accommodating cavity 321 for clamping, and the positioning accuracy and reliability of the reaction vessel 820 are improved.
It can be appreciated that the mixing device 700 of the present invention solves the problem that the reaction vessel 820 cannot be vertically taken and placed and has poor positioning accuracy based on the fixed-inclination mixing scheme in the prior art. Meanwhile, the mixing mechanism 100 in the mixing device 700 can realize the effects of mixing trace samples and collecting the trace samples at the bottom, and the situation that partial samples are attached to the side wall of the reaction container 820 and cannot be mixed completely is avoided.
In this embodiment, the reaction vessel 820 of the mixing mechanism 100 may be a round tube reaction cup, an inner octagon tube reaction cup, a vacuum blood collection tube, a micro vacuum blood collection tube, a square tube reaction cup, etc., which is not limited herein. Meanwhile, the reaction vessel 820 to which the mixing mechanism 100 is applicable includes not only a reaction cup for luminescence, but also reaction cups for other instruments, such as blood cells, biochemistry, coagulation, etc., that is, the mixing device 700 can be applied to the fields of blood cells, biochemistry, coagulation, etc., without limitation.
It can be understood that, in the mixing device 700, by adding a horizontally moving traversing assembly 420 on the basis of a lifting mechanism, the mixing mechanism 100 can be sleeved on the bottom of the reaction vessel 820 and then horizontally moved, so that the axis of the placement hole of the top reaction vessel 820 coincides with the main axis of the crankshaft 22 of the mixing mechanism 100, the axis of the reaction vessel 820 can be uniformly mixed around the main axis 221 of the crankshaft 22 in a conical surface during mixing, and the reaction vessel 820 can return to a vertical state when being sleeved in and separated from the accommodating cavity 321 of the vessel seat 32, thereby avoiding the failure of the reaction vessel 820.
In one embodiment, the base 1 is provided with a mounting hole 12, the driving assembly 2 comprises a driving piece 21 and a crankshaft 22, the crankshaft 22 comprises a main shaft 221 and an eccentric shaft 222, one end of the main shaft 221 is rotatably arranged in the mounting hole 12 and connected with the eccentric shaft 222, the axis of the eccentric shaft 222 is parallel to and not coincident with the axis of the crankshaft 22, the eccentric shaft 222 is movably connected with the swinging frame 31, the driving piece 21 comprises a rotating motor 211, a driven wheel 213 and a driving belt 214, the rotating motor 211 is arranged on the base 1, an output shaft of the rotating motor 211 is provided with a driving wheel 212, the driven wheel 213 is sleeved on the main shaft 221, and the driving belt 214 is sleeved on the driving wheel 212 and the driven wheel 213;
Wherein the rotary motor 211 drives the driving wheel 212 to rotate, so that the driving belt 214 drives the driven wheel 213 and the crankshaft 22 to rotate.
In the present embodiment, as shown in fig. 1 to 9, by providing the driving assembly 2 as the driving piece 21 and the crankshaft 22, the connection of the driving piece 21 and the swing frame 31 is achieved by the crankshaft 22 to provide the driving force to the swing frame 31 through the driving piece 21. It is understood that the driving member 21 may be a driving motor, a transmission motor, a servo motor, a rotating motor, etc., which is not limited herein. Of course, in other embodiments, the driving member 21 may also be configured by a driving motor in combination with a driving wheel, a driving gear, or a timing belt, which is not limited herein.
In an embodiment, as shown in fig. 1 to 9, the driving member 21 includes a rotating motor 211, a driven wheel 213 and a driving belt 214, wherein the rotating motor 211 is disposed on the base 1, an output shaft of the rotating motor 211 is provided with a driving wheel 212, the driven wheel 213 is sleeved on the crankshaft 22, and the driving belt 214 is sleeved on the driving wheel 212 and the driven wheel 213, wherein the rotating motor 211 drives the driving wheel 212 to rotate, so that the driving belt 214 drives the driven wheel 213 and the crankshaft 22 to rotate.
In this embodiment, the rotary motor 211 is fixedly mounted on the base 1, so that the driving member 21 is reasonably mounted and the driving member 21 is connected with the crankshaft 22, the output shaft of the rotary motor 211 rotates to penetrate through the base 1, the output shaft of the rotary motor 211 is provided with a driving wheel 212, a driven wheel 213 is sleeved on the crankshaft 22, and a driving belt 214 is sleeved on the driving wheel 212 and the driven wheel 213 to realize transmission connection of the rotary motor 211 and the crankshaft 22.
It will be appreciated that when the rotary motor 211 drives the driving wheel 212 to rotate, the belt 214 drives the driven wheel 213 and the crankshaft 22 to rotate. Optionally, the rotating motor 211 provides power to the mixing assembly 3, and in order to ensure the precision of returning to the original position when the container base 32 is mixed, optionally, a stepping motor is used as the rotating motor 211.
In this embodiment, as shown in fig. 2 to 4, the crankshaft 22 includes a main shaft 221 and an eccentric shaft 222 that are connected, one end of the main shaft 221 is in transmission connection with the driving member 21, that is, the driven wheel 213 is sleeved on the main shaft 221 of the crankshaft 22, and the other end of the main shaft 221 is rotatably disposed through the mounting hole 12 and connected with the eccentric shaft 222. It will be appreciated that the main shaft 221 of the crankshaft 22 is rotatably connected to the base 1.
In one embodiment, as shown in FIG. 4, a bearing member is provided in the mounting hole 12, and the main shaft 221 passes through the bearing member and is connected to the eccentric shaft 222. It will be appreciated that the spindle 221 of the spindle 221 is rotatably connected to the base 1 by means of bearing members.
In the present embodiment, the eccentric shaft 222 of the crankshaft 22 and the driven pulley 213 are located on both sides of the base 1. Alternatively, the diameter of the main shaft 221 of the crankshaft 22 is larger than the diameter of the eccentric shaft 222. Of course, in other embodiments, the diameter of the main shaft 221 of the crankshaft 22 may be less than or equal to the diameter of the eccentric shaft 222, which is not limited herein.
In one embodiment, as shown in fig. 4, a mounting table 223 is disposed at an end of the main shaft 221 passing through the mounting hole 12, and the eccentric shaft 222 is disposed at an end of the mounting table 223 opposite to the main shaft 221 and is located at an edge of the mounting table 223, such that an axis of the eccentric shaft 222 is parallel to and not coincident with an axis of the crankshaft 22.
In this embodiment, the axis of the main shaft 221 is parallel to and not coincident with the axis of the eccentric shaft 222. As shown in fig. 2, 5 and 6, the distance d between the axis of the eccentric shaft 222 and the axis of the crankshaft 22 is d, alternatively, the distance d between the axis of the eccentric shaft 222 and the axis of the crankshaft 22 ranges from 0.1mm to 2mm, for example, the distance d is 0.1mm, 0.2mm, 0.3mm, 0.4mm, 0.5mm, 0.6mm, 0.7mm, 0.8mm, 0.9mm, 1mm, 1.3mm, 1.5mm, 1.8mm, 2mm, etc., without limitation herein.
It will be appreciated that the arrangement is such that when the driving member 21 drives the main shaft 221 of the crankshaft 22 to rotate, the eccentric shaft 222 of the crankshaft 22 rotates around the axis of the main shaft 221, and meanwhile, the axis of the eccentric shaft 222 is parallel to and not coincident with the axis of the crankshaft 22, so that when the eccentric shaft 222 drives the swinging frame 31 to rotate, the swinging frame 31 will swing, and the swinging frame 31 drives the container holder 32 to swing. In this embodiment, the reaction vessel 820 and the vessel holder 32 have a common theoretical axis, and when the vessel holder 32 drives the reaction vessel 820 to swing relative to the swing frame 31, the theoretical axis forms an angle α with the eccentric shaft 222 of the crankshaft 22, the angle α is 0 in a non-uniform static state, i.e. the reaction vessel 820 and the vessel holder 32 are both in a vertical state, and the angle is greater than 0 in uniform mixing.
Meanwhile, the problem that the included angle between the reaction container 820 and the axis of the container base 32 cannot be too large is solved, so that when the reaction container 820 is not uniformly mixed, the reaction container 820 can be inserted into or separated from the accommodating cavity 321 of the container base 32 in a vertical state, the reaction container 820 is not easy to fall off, and when the reaction container 820 is uniformly mixed, the reagent can be more easily moved back and forth in a horizontal plane in the reaction container 820 at a larger swing angle.
In this embodiment, when the driving member 21 drives the main shaft 221 of the crankshaft 22 to rotate, the swinging frame 31 drives the container base 32 to rotate around the axis of the main shaft 221, and after the swinging frame 31 generates swinging force, the container base 32 can swing relative to the swinging frame 31, so as to improve the mixing effect of the sample liquid in the reaction container 820.
In an embodiment, the swing frame 31 includes a rotating seat 311 and a supporting frame 312, wherein the rotating seat 311 is provided with a connecting hole 3111, an end of the eccentric shaft 222 away from the main shaft 221 is rotatably disposed through the connecting hole 3111 through a bearing member, the supporting frame 312 is disposed on the rotating seat 311, the supporting frame 312 is provided with a swing slot 3123, and the container seat 32 is swingably disposed in the swing slot 3123.
In the present embodiment, as shown in fig. 1 to 6, the swing frame 31 is connected to the eccentric shaft 222 of the crankshaft 22 through a rotation seat 311. The rotating seat 311 is provided with a connecting hole 3111, and the eccentric shaft 222 is rotatably arranged through the connecting hole 3111 by a bearing member, so that the eccentric shaft 222 is connected with the rotating seat 311.
It can be appreciated that the support frame 312 is disposed on the rotating seat 311, and the swing groove 3123 is disposed on the support frame 312, so that the container seat 32 is swingably disposed in the swing groove 3123. In the present embodiment, the receptacle 32 is accommodated in the swing groove 3123, and the receptacle 32 is rotatably connected or hinged to the groove wall of the swing groove 3123, which is not limited herein.
The arrangement solves the problem that the included angle between the reaction container 820 and the container seat 32 is invariable, and ensures that the liquid in the reaction container 820 is easier to reciprocate in the horizontal direction to mix evenly when the container seat 32 drives the reaction container 820 to reciprocate relative to the rotating seat 311. Simultaneously, the problem that noise is great when current mixing structure is rigid structure mixing has still been solved.
In an embodiment, as shown in fig. 2, 3, 5 and 6, a clamping groove 224 is disposed at an end of the eccentric shaft 222 away from the main shaft 221, and the driving assembly 2 further includes a clamping ring 23, where the clamping ring 23 is clamped in the clamping groove 224. It can be appreciated that the clamping groove 224 is formed on the eccentric shaft 222, and the clamping ring 23 is clamped in the clamping groove 224, so that the clamping ring 23 is in limited abutting connection with the bearing member in the connection hole 3111 of the rotating seat 311, and the connection stability of the rotating seat 311 and the eccentric shaft 222 is improved.
In an embodiment, the support frame 312 includes a base 3121 and two support arms 3122, wherein the base 3121 is disposed on the rotating seat 311, the two support arms 3122 are disposed at intervals on a side of the base 3121 facing away from the rotating seat 311, the two support arms 3122 are disposed opposite to each other and cooperate with the base 3121 to form a swinging slot 3123 and two through openings 3124 communicating with the swinging slot 3123, each support arm 3122 is provided with a shaft hole 3125, the outer wall of the container seat 32 is provided with a rotating shaft 322 corresponding to each shaft hole 3125, and the rotating shaft 322 is rotatably disposed through the shaft hole 3125.
In the present embodiment, as shown in fig. 1, 3 and 4, the base 3121 of the supporting frame 312 is fixedly connected with the rotating seat 311, and is located on a side wall of the rotating seat 311 opposite to the base 1, and optionally, the rotating seat 311 is disposed parallel to the base 1. The two support arms 3122 are disposed at intervals and opposite to the base 3121 of the support frame 312 such that the two support arms 3122 cooperate with the base 3121 to form a swing groove 3123 and two through openings 3124 communicating with the swing groove 3123.
It can be understood that the two through openings 3124 of the support frame 312 are located at opposite sides of the swing groove 3123 and are communicated with the swing groove 3123, and the connection line of the two through openings 3124 is perpendicular to the connection line of the two support arms 3122.
In the present embodiment, the support arm 3122 is provided with the shaft holes 3125, and the outer wall of the container base 32 is provided with the rotating shaft 322 corresponding to each shaft hole 3125, so that when the container base 32 is accommodated in the swinging slot 3123, the container base 32 is rotatably connected with the support arm 3122 through the rotating shaft 322 and the shaft holes 3125.
Optionally, the shaft hole 3125 is located at an end of the support arm 3122 away from the base 3121, and the rotation shaft 322 is located at an end of the receptacle 32 adjacent to an opening of the accommodating cavity 321. As described above, when the receptacle 32 swings with respect to the support frame 312 of the swing frame 31, the receptacle 32 swings around the rotation shaft 322 in the swing groove 3123. Alternatively, during the swinging of the container base 32, an end of the container base 32 away from the rotating shaft 322 may extend out of the swinging slot 3123 through the through opening 3124, which is not limited herein.
In an embodiment, the swing frame 31 further includes an anti-collision rod 313, where the anti-collision rod 313 is disposed on the rotating seat 311 and corresponding to the through hole 3124, and when the container seat 32 swings around the rotating shaft 322, one end of the container seat 32 away from the rotating shaft 322 extends out of the through hole 3124 and is in limiting abutment with the anti-collision rod 313.
In this embodiment, as shown in fig. 1 to 7 and 9, by providing the anti-collision bar 313, the anti-collision bar 313 is provided corresponding to the through hole 3124, so that when the container base 32 swings by using the anti-collision bar 313, the swinging angle of the container base 32 is limited, and the phenomenon that the sample liquid in the reaction container 820 is spilled due to the overlarge swinging angle of the container base 32 is avoided.
It will be appreciated that, as shown in fig. 2, 5 and 6, when the receptacle 32 is stationary, the axis of the receptacle 32 coincides with the axis of the eccentric shaft 222 of the crankshaft 22, and when the receptacle 32 swings, the axis of the receptacle 32 forms an angle α with the axis of the eccentric shaft 222 of the crankshaft 22, and the angle α is greater than 0. Alternatively, the included angle α is greater than 0 and less than or equal to 45 °, for example, the included angle α is 5 °, 8 °,10 °, 13 °,15 °, 18 °, 20 °, 23 °, 25 °, 28 °, 30 °,33 °, 35 °, 38 °, 40 °, 43 °, 45 °, etc., without limitation.
In the present embodiment, the distance between the setting position of the rotation seat 311 and the through hole 3124 of the anti-collision rod 313 is limited by the swing angle of the swing of the container seat 32, that is, when the container seat 32 swings, the axis of the container seat 32 and the axis of the eccentric shaft 222 of the crankshaft 22 form an included angle α which cannot be too large or too small, and the phenomenon that the sample liquid in the reaction container 820 is spilled out is easily caused by too large included angle α, and the problem that the mixing effect of the sample liquid in the reaction container 820 is poor is caused by too small included angle α.
It will be appreciated that the provision of the anti-collision bar 313 serves to limit the magnitude of the angle of oscillation of the receptacle 32 during blending, and that when the blending speed is sufficiently high, the receptacle 32 will oscillate and be blocked by the anti-collision bar 313.
In an embodiment, the swing frame 31 further includes an elastic member 314, one end of the elastic member 314 is connected to the bottom of the container base 32, and the other end of the elastic member 314 is connected to the base 3121 or the crash bar 313.
In this embodiment, as shown in fig. 5 and 6, by providing the elastic member 314, one end of the elastic member 314 is connected to the bottom of the receptacle 32, and the other end of the elastic member 314 is connected to the base 3121 or the anti-collision rod 313, so that when the receptacle 32 swings by using the elastic member 314, the receptacle 32 is reset, and meanwhile, the phenomenon that the sample liquid in the reaction vessel 820 is spilled due to an excessive swing angle in the swinging process of the receptacle 32 can be avoided.
Optionally, the elastic member 314 is a spring, such as a return spring, so that the elastic member 314 is used to provide damping, reducing vibration of the receptacle 32, and thus reducing noise and splashing of the liquid in the reaction vessel 820. In one embodiment, as shown in fig. 5, one end of the elastic member 314 is connected to the bottom of the receptacle 32, and the other end of the elastic member 314 is connected to the base 3121. In the present embodiment, the bumper bar 313 may or may not be provided, and is not limited thereto. In another embodiment, as shown in fig. 6, one end of the elastic member 314 is connected to the bottom of the receptacle 32, and the other end of the elastic member 314 is connected to the bumper bar 313, which is not limited herein.
In this way, the elastic member 314 can be used to tighten the receptacle 32 and the base 3121 or the crash bar 313, so that the receptacle 32 and the reaction vessel 820 are in the normal vertical state in the non-uniform static state, and the swing angle of the receptacle 32 is limited together with the gravity of the receptacle 32 in the uniform state. It can be appreciated that the elastic member 314 can also be arranged to increase the speed of the driving member 21, so as to shorten the mixing time and increase the detection speed.
Alternatively, the two anti-collision bars 313 include two anti-collision bars 313 respectively disposed on opposite sides of the base 3121 and corresponding to the two through openings 3124, the elastic members 314 include two elastic members 314, one ends of the two elastic members 314 are connected to the bottom of the container base 32, and the other ends of the two elastic members 314 are connected to the two anti-collision bars 313 respectively.
It will be appreciated that this arrangement further ensures resetting and also avoids spillage of the sample liquid in the reaction vessel 820 due to excessive rocking angle during rocking of the receptacle 32.
In an embodiment, as shown in fig. 1,2, 5 and 6, a reset weight 323 is disposed at the bottom of the container base 32, and one end of the elastic member 314 is connected to the reset weight 323.
It can be appreciated that the setting of the reset weight 323 is convenient for the connection between the elastic member 314 and the container base 32, and the reset weight 323 also plays a role in the quick stationary reset of the container base 32 when the driving member 21 stops working. That is, in the gravity resetting scheme, the additional weight is added to the resetting weight 323 to limit the deflection angle of the container base 32 and the reaction container 820 when they are mixed uniformly, and to reset the container base 32 and the reaction container 820 when they are not mixed uniformly.
In an embodiment, the base 1 is further provided with a chute 11, the chute 11 extends towards the mounting hole 12, the swing frame 31 further comprises a guide rod 315 provided on the rotating seat 311, and one end of the guide rod 315 away from the rotating seat 311 slidably extends into the chute 11.
It can be appreciated that when the driving member 21 drives the crankshaft 22 to rotate the rotating base 311, the guiding rod 315 moves along the sliding slot 11, so that the rotating base 311 reciprocates along the extending direction of the sliding slot 11.
In this embodiment, as shown in fig. 1 to 8, by providing the chute 11 on the base 1 and providing the guide rod 315 on the rotating seat 311 of the swinging frame 31, one end of the guide rod 315 far away from the rotating seat 311 slidably extends into the chute 11, so that when the driving member 21 drives the crankshaft 22 to drive the rotating seat 311 to rotate, the guide rod 315 moves along the chute 11 to make the rotating seat 311 reciprocate along the extending direction of the chute 11, thereby further ensuring the swinging of the container seat 32. Optionally, a rolling bearing 3151 is provided at an end of the guide rod 315 extending into the chute 11, thereby improving the guide effect.
It will be appreciated that the extending direction of the chute 11 is consistent with the swinging direction of the receptacle 32, that is, the extending direction of the chute 11 is parallel or coincident with the line connecting the two openings 3124 on the swinging frame 31, which is not limited herein. That is, the guide bar 315 is engaged with the chute 11, which can be used to prevent the receptacle 32 from rotating when rotating about the main shaft 221 of the crankshaft 22, so that the guide bar 315 is engaged with the chute 11 to provide the reciprocating motion to the guide bearing of the receptacle 32.
Of course, as shown in fig. 9, the guide rod 315 and the chute 11 may not be provided, so that when the driving member 21 drives the main shaft 221 of the crankshaft 22 to rotate, the eccentric shaft 222 drives the rotating seat 311 to rotate around the main shaft 221, and the rotating seat 311 can rotate around the eccentric shaft 222, thereby ensuring the mixing effect.
As shown in fig. 1 to 8, the swing frame 31 is provided with the guide bar 315, and the receptacle 32 swings back and forth, so that there are two left and right impact bars 313, and as shown in fig. 9, the swing frame 31 is not provided with the guide bar 315, and the receptacle 32 swings away from the main shaft 221 of the crankshaft 22, so that there is only one impact bar 313.
It will be appreciated that, for the solution of providing the guide rod 315 on the swinging frame 31, the mixing device 700 rotates under the rotation of the crankshaft 22 driven by the rotating motor 211 in the static non-mixing state, the rotating motor 211 stops after the rotating blocking piece 634 triggers the rotating optocoupler 632 to move a certain distance, and the container 32 stops at a fixed home position and returns to a static vertical state under the action of gravity or a spring or both.
When the reaction vessel 820 is vertically inserted into the receiving cavity 321 of the vessel holder 32, the cup-moving gripper of the reaction vessel 820 is separated from the reaction vessel 820 (the cup-moving gripper of the reaction vessel 820 can grasp or put down the reaction vessel 820 from the vertical upper side of the reaction vessel 820, or can grasp or separate from the side of the reaction vessel 820. Optionally, when the gripper grasps or separates from the reaction vessel 820 from the side, if there is a lateral force on the reaction vessel 820, the gripper will go in and out in the same direction as the rotation axis of the swing of the vessel holder 32, so as to avoid the swing angle of the vessel holder 32 not being in the vertical state when the reaction vessel 820 is grasped or separated laterally.
The rotating motor 211 drives the crankshaft 22 to drive the container base 32 to revolve around the main shaft 221 of the crankshaft 22, at this time, the container base 32 cannot rotate around the eccentric shaft 222 of the crankshaft 22 because of the crank-link slider mechanism formed by the guide rod 315 and the crankshaft 22 in the horizontal plane, and can only reciprocate around the horizontal rotating shaft of the container base 32 in the vertical plane under the action of centrifugal force while revolving, so that the sample to be measured in the reaction container 820 can revolve, reciprocate and reciprocate up and down at the same time, and is easier to mix uniformly.
When the mixing is completed, the receptacle 32 is returned to its original position and is reset to the vertical state, and the reaction vessel 820 is grasped away, and the mixing is completed.
It will be appreciated that the other steps are the same as the above-described arrangement of the guide bar 315 for the swing frame 31, except that the guide bar 315 is not provided for the swing frame 31, and that the receptacle 32 rotates around the eccentric shaft 222 of the crankshaft 22 while revolving around the main shaft 221 of the crankshaft 22 only when the receptacle 32 starts to rotationally mix, so that the receptacle 32 swings only in an outer direction away from the main shaft 221 of the crankshaft 22, and does not swing reciprocally in a vertical plane. Of course, in order to achieve a good mixing effect, the rotating motor 211 may be provided to achieve mixing in a forward or reverse rotation manner, and the mixing is not limited thereto.
The above-described arrangement of the swing frame 31 with or without the guide bar 315 may be used for all the different reaction vessels 820 of the reaction cup or tube. For the resetting scheme of the container base 32, a gravity resetting scheme of the container base 32 or adding a counterweight can be adopted, and a scheme of resetting under the combined action of a single spring or a double spring in a vertical plane can also be adopted. It will be appreciated that the blending rotation speed of the receptacle 32 of the blending mechanism 100 in the spring return arrangement may be relatively high and noiseless. In the gravity return scheme, when the rotation speed is low, the container base 32 does not strike the anti-collision rod 313 and does not generate noise, such as when the anti-collision rod 313 adopts a harder elastic element, the container base is also noiseless.
In an embodiment, the lifting assembly 520 includes a lifting motor 521, a synchronizing wheel 523 and a timing belt 524, the lifting motor 521 is disposed on the substrate 510, a driving wheel 522 is disposed on an output shaft of the lifting motor 521, the synchronizing wheel 523 is rotatably disposed on the substrate 510 and is spaced from and opposite to the driving wheel 522, the timing belt 524 is sleeved on the driving wheel 522 and the synchronizing wheel 523, and the timing belt 524 is fixedly connected with the base 1, wherein the lifting motor 521 drives the driving wheel 522 to rotate, so that the timing belt 524 drives the base 1 to lift along the first direction.
In this embodiment, as shown in fig. 7 to 11, the lifting motor 521 is fixedly mounted on the base plate 510, for reasonable assembly, the output shaft of the lifting motor 521 rotatably penetrates the base plate 510, the output shaft of the lifting motor 521 is provided with a driving wheel 522, and the synchronizing wheel 523 is rotatably mounted on the base plate 510, such that the synchronizing wheel 523 is spaced from and opposite to the driving wheel 522, and the synchronizing belt 524 is sleeved on the driving wheel 522 and the synchronizing wheel 523, such that when the lifting motor 521 drives the driving wheel 522 to rotate, the synchronizing belt 524 drives the synchronizing wheel 523 to rotate.
It can be appreciated that the base 1 of the blending mechanism 100 is provided with a fixing member, and the base 1 is fixedly connected to one side of the synchronous belt 524 through the fixing member, so that when the lifting motor 521 drives the driving wheel 522 to rotate forward or backward, the synchronous belt 524 drives the base 1 to lift. In this embodiment, the use of the timing belt 524 in conjunction with the timing wheel 523 can be used as an idler for tensioning and guiding the timing belt 524 and for power transmission. Alternatively, the lift motor 521 may be a stepper motor.
In an embodiment, as shown in fig. 7 to 11, the base 510 is provided with a sliding rail 511, the sliding rail 511 is parallel to and spaced apart from the timing belt 524, and the base 1 is provided with a sliding slot slidably engaged with the sliding rail 511.
It will be appreciated that by providing the slide rail 511 on the base 510 and providing the slide groove slidably engaged with the slide rail 511 on the base 1, the slide rail 511 is utilized to provide guiding for lifting of the mixing mechanism 100. In this embodiment, the sliding rail 511 and the sliding groove may adopt a wedge-shaped limit fit structure or a dovetail limit fit structure, for example, the sliding rail 511 is in a wedge-shaped or dovetail-shaped structure, and the shape of the sliding groove is adapted to the shape of the sliding rail 511, so that the mixing mechanism 100 is in limit fit with the sliding rail 511 through the sliding groove.
In one embodiment, the traversing assembly 420 includes a traversing motor 421, a synchronous pulley and a traversing belt 424, the traversing motor 421 is disposed on the mounting frame 410, a driving pulley 422 is disposed on an output shaft of the traversing motor 421, the synchronous pulley is rotatably disposed on the mounting frame 410 and spaced from and opposite to the driving pulley 422, the traversing belt 424 is sleeved on the driving pulley 422 and the synchronous pulley, and the traversing belt 424 is fixedly connected with the substrate 510, wherein the traversing motor 421 drives the driving pulley 422 to rotate, so that the traversing belt 424 drives the substrate 510 to traverse along the second direction.
In this embodiment, as shown in fig. 10 and 11, the traversing motor 421 is fixedly installed on the mounting frame 410, for reasonable assembly, the output shaft of the traversing motor 421 rotatably penetrates through the mounting frame 410, and the output shaft of the traversing motor 421 is provided with a driving pulley 422 and rotationally locates the synchronous pulley on the mounting frame 410, so that the synchronous pulley is spaced from the driving pulley 422 and is oppositely located, and the traversing belt 424 is sleeved on the driving pulley 422 and the synchronous pulley, so that when the traversing motor 421 drives the driving pulley 422 to rotate, the traversing belt 424 drives the synchronous pulley to rotate.
It can be appreciated that the base plate 510 of the lifting mechanism is provided with a fixing member, and the base plate 510 is fixedly connected to one side of the traverse belt 424 through the fixing member, so that when the traverse motor 421 drives the driving pulley 422 to rotate forward or backward, the traverse belt 424 drives the base plate 510 to reciprocate along the second direction. In this embodiment, use of the traversing belt 424 in combination with a synchronous pulley may be used as an idler for both tensioning and guiding the traversing belt 424 and for power transfer. Alternatively, the traverse motor 421 may be a stepping motor.
In one embodiment, as shown in fig. 10 and 11, the mounting frame 410 is provided with a guide rail 411, the guide rail 411 is parallel to and spaced apart from the traverse belt 424, and the base plate 510 is provided with a guide groove slidably engaged with the guide rail 411.
It will be appreciated that the guide 411 is provided on the mounting frame 410 and a guide slot is provided on the base plate 510 that slidably engages with the guide 411, thereby providing guidance for traversing of the lifting mechanism and blending mechanism 100 by way of the guide 411. In this embodiment, the guide rail 411 and the guide groove may adopt a wedge-shaped limit fit structure or a dovetail limit fit structure, for example, the guide rail 411 is in a wedge-shaped or dovetail-shaped structure, and the shape of the guide groove is adapted to the shape of the guide rail 411, so that the base plate 510 of the lifting mechanism is in limit fit with the guide rail 411 through the guide groove.
In this embodiment, the mixing device 700 adopts a scheme of a two-dimensional mixing assembly with horizontal movement and vertical lifting, that is, a traversing assembly 420 is added on the basis that the lifting mechanism drives the mixing mechanism 100 to lift in the first direction, so that the traversing assembly 420 drives the lifting mechanism and the mixing mechanism 100 to integrally realize horizontal movement along the second direction, the mixing mechanism 100 can be sleeved on the bottom of the reaction vessel 820 upwards and then horizontally moved, so that the axis of the placing hole of the top reaction vessel 820 coincides with the main shaft 221 of the crankshaft 22, the axis of the reaction vessel 820 can be uniformly mixed around the main shaft 221 in a conical surface during mixing, and the reaction vessel 820 can return to a vertical state when being sleeved in and separated from the accommodating cavity 321 of the vessel seat 32, thereby avoiding the failure of the reaction vessel 820.
It can be appreciated that the two-dimensional scheme of horizontal and vertical lifting can enable the reaction vessel 820 such as a reaction cup and a test tube to be inserted or separated in a state of the eccentricity d=0 and the swing angle α=0 when being inserted or separated from the accommodating cavity 321 of the vessel base 32, and the positioning accuracy and the guiding are more reliable. When the eccentricity d >0 and the swing angle alpha >0 are required to be uniformly mixed, the horizontal traversing assembly 420 can change the eccentricity d and the corresponding swing angle alpha. Accordingly, if one-dimensional rectilinear motion is continuously increased on the basis of the horizontal and vertical two-dimensional components, the mixing device 700 becomes a three-dimensional mixing mechanism, which is not limited herein.
In an embodiment, the blending apparatus 700 further includes a lateral movement detecting assembly 610, where the lateral movement detecting assembly 610 includes a mounting plate 611, a lateral movement optical coupler 612, and a lateral movement blocking piece, the mounting plate 611 is disposed on the mounting plate 410, the lateral movement optical coupler 612 is disposed on the mounting plate 611, the lateral movement optical coupler 612 is provided with a detecting groove 613, one end of the lateral movement blocking piece is connected to the substrate 510, and the other end of the lateral movement blocking piece extends toward the mounting plate 611.
It can be appreciated that when the traversing assembly 420 drives the substrate 510 to move along the second direction of the mounting frame 410, the substrate 510 drives the traversing baffle to pass through the detecting groove 613, so that the traversing optocoupler 612 senses detection.
In the present embodiment, as shown in fig. 10 and 11, by providing the traverse detecting unit 610, the traverse baffle attached to the substrate 510 is detected or sensed by the traverse optocoupler 612 of the traverse detecting unit 610 to control the operation state of the traverse motor 421. It will be appreciated that the traverse detection assembly 610 is configured to control the horizontal movement distance of the substrate 510 along the second direction of the mounting frame 410.
It will be appreciated that the traverse detecting assembly 610 is mounted and fixed on the mounting frame 410 by the mounting plate 611, and the mounting plate 611 may be disposed on the mounting frame 410 by welding, bonding or integrally forming, so as to improve the mounting stability of the traverse detecting assembly 610. Of course, the mounting plate 611 may also be detachably mounted on the mounting frame 410 by a manner of a snap connection, a plug-in fit, a screw connection or a pin connection, so as to improve the convenience of dismounting the traverse motion detection assembly 610.
In this embodiment, the traversing optocoupler 612 may be an infrared sensor or an optocoupler sensor, and by providing the detecting groove 613, when the traversing baffle passes along the substrate 510 and moves laterally, the traversing baffle passes through the detecting groove 613, so that the traversing optocoupler 612 senses and detects, and feeds back a signal to the traversing motor 421 to control the substrate 510 to move along the second direction of the mounting frame 410. Optionally, the traversing optocoupler 612 is electrically connected to the traversing motor 421, or the traversing optocoupler 612 is electrically connected to a master control system or controller or control circuit of the blending apparatus 700, which is not limited herein. Optionally, the lateral moving baffle plate can be a sheet metal plate.
In an embodiment, the mixing device 700 further includes a lifting detection component 620, the lifting detection component 620 includes a fixing frame 621, a lifting optocoupler 622 and a lifting baffle 624, the fixing frame 621 is disposed on the substrate 510, the lifting optocoupler 622 is disposed on the fixing frame 621, the lifting optocoupler 622 is provided with a detection opening 623, one end of the lifting baffle 624 is connected to the base 1, and the other end of the lifting baffle 624 extends towards the substrate 510.
It can be appreciated that when the lifting assembly 520 drives the base 1 to move up and down along the substrate 510, the base 1 drives the lifting baffle 624 to pass through the detection opening 623, so that the lifting optocoupler 622 senses detection.
In this embodiment, as shown in fig. 7 to 10, the lifting detection assembly 620 is provided, so that the lifting optical coupler 622 of the lifting detection assembly 620 is used to detect or sense the lifting baffle 624 connected to the base 1 of the mixing mechanism 100, so as to control the working state of the lifting motor 521. It will be appreciated that the lift detection assembly 620 is configured to control the height of the mixing mechanism 100 along the substrate 510.
It can be appreciated that the lifting detection assembly 620 is fixed on the substrate 510 through the fixing frame 621, and the fixing frame 621 can be welded, adhered or integrally formed on the substrate 510, so as to improve the installation stability of the lifting detection assembly 620. Of course, the fixing frame 621 may be detachably mounted on the base plate 510 by a manner of fastening, inserting, screwing or pinning, so as to improve the convenience of mounting and dismounting the lifting detection assembly 620.
In this embodiment, the lifting optocoupler 622 may be an infrared sensor or an optocoupler sensor, and by setting the detection opening 623, when the lifting baffle 624 moves up and down along with the base 1 of the mixing mechanism 100, the lifting baffle 624 passes through the detection opening 623, so that the lifting optocoupler 622 senses detection, and feeds a feedback signal to the lifting motor 521 to control the lifting height of the mixing mechanism 100 along the substrate 510. Optionally, the lifting optocoupler 622 is electrically connected to the lifting motor 521, or the lifting optocoupler 622 is electrically connected to a main control system or a controller or a control circuit of the blending device 700, which is not limited herein. Optionally, the lifting baffle 624 may be a sheet metal plate.
In an embodiment, the mixing device 700 further includes a rotation detecting assembly 630, the rotation detecting assembly 630 includes a bracket 631, a rotary optocoupler 632 and a rotary blocking piece 634, the bracket 631 is disposed on the base 1, the rotary optocoupler 632 is disposed on the bracket 631, the rotary optocoupler 632 is provided with a detection notch 633, one end of the rotary blocking piece 634 is connected to the driving assembly 2, and the other end of the rotary blocking piece 634 extends toward the detection notch 633.
It can be appreciated that when the driving member 21 of the mixing mechanism 100 drives the crankshaft 22 to rotate, the crankshaft 22 drives the rotating baffle 634 to pass through the detecting notch 633, so that the rotating optocoupler 632 senses detection.
In this embodiment, as shown in fig. 1, 7, 9 and 10, the rotation detection assembly 630 is provided, so that the rotation optical coupler 632 of the rotation detection assembly 630 is used to detect or sense the rotation baffle 634 connected to the crankshaft 22 of the mixing mechanism 100, so as to control the working state of the rotating motor 211 of the driving member 21. It will be appreciated that the rotation detection assembly 630 is configured to control the rotation of the crankshaft 22 driven by the rotary motor 211.
It can be appreciated that the rotation detecting assembly 630 is mounted and fixed on the base 1 of the mixing mechanism 100 by the bracket 631, and the bracket 631 can be welded, adhered or integrally formed on the base 1, so as to improve the mounting stability of the rotation detecting assembly 630. Of course, the bracket 631 may also be detachably mounted on the base 1 by a manner of a snap connection, a plug connection, a screw connection or a pin connection, so as to improve the convenience of dismounting the rotation detecting assembly 630.
In this embodiment, the rotary optocoupler 632 may be an infrared sensor or an optocoupler sensor, and the detection notch 633 is provided, so that when the rotary baffle 634 rotates along with the crankshaft 22, the rotary baffle 634 passes through the detection notch 633, so that the rotary optocoupler 632 senses and detects, and feeds back a signal to the rotary motor 211 to control the rotary motor 211 to drive the crankshaft 22 to rotate. Optionally, the rotating optocoupler 632 is electrically connected to the rotating motor 211, or the rotating optocoupler 632 is electrically connected to a main control system or a controller or a control circuit of the mixing device 700, which is not limited herein.
As shown in fig. 10 and 11, the present invention also proposes a sample analyzer 900, where the sample analyzer 900 includes a device main body and the above-mentioned mixing device 700, and the mixing device 700 is disposed on the device main body. The specific structure of the mixing device 700 refers to the foregoing embodiments, and since the sample analyzer adopts all the technical solutions of all the foregoing embodiments, the sample analyzer has at least all the beneficial effects brought by the technical solutions of the foregoing embodiments, and will not be described in detail herein.
In this embodiment, the apparatus body is provided with a disc 810 and a plurality of reaction vessels 820, the disc 810 is provided with a plurality of mounting openings 811, each reaction vessel 820 is detachably provided at one of the mounting openings 811, the mixing device 700 is provided at the apparatus body, and the accommodating cavity 321 of the mixing device 700 is opposite to one of the reaction vessels 820.
It is understood that reaction vessel 820 may alternatively be a cuvette or tube for providing a container for sample, reagent addition, reaction, homogenization, or detection to an instrument. The test tube is used for collecting and preserving an elongated tubular bottle of a sample to be tested, and can be used with a cap for sealing or uncapping.
In this embodiment, the reaction cup or test tube may be selected from a round tube reaction cup, an inner octagon round tube reaction cup, a vacuum blood collection tube, a micro vacuum blood collection tube, a square tube reaction cup, etc., which is not limited herein. It is understood that the inner and outer walls of the circular tube reaction cup are cylindrical tube reaction cups, and in particular, the reaction cup used in the chemiluminescence field is taken as an example. The inner wall of the reaction cup with the inner octagon round tube is divided into an upper section and a lower section, the upper section is the reaction cup with the inner octagon round tube, the lower section is the reaction cup with the cylindrical tube, and the reaction cup used in the coagulation field is taken as an example. The vacuum blood collection tube is exemplified by a cylindrical vacuum blood collection tube for blood cells and biochemistry. The micro-vacuum blood collection tube is particularly exemplified by a micro-vacuum blood collection tube for blood cells, and the sample to be tested is not at the bottom of the test tube but at the middle of the test tube because the sample to be tested is less. The inner and outer walls of the square tube reaction cup are square or rectangular reaction cups, and are not limited in this regard, particularly square cups used in the field of chemiluminescence are taken as examples.
The mixing device 700 of the present invention solves the problem of the prior art that a reaction cup or test tube must have a fixed angle α or eccentricity d with the axis of the cup holder when it is lowered to the end when it is inserted down into the cup holder. The test tube clamping device has the advantages of avoiding the problem that the positioning accuracy is affected by lateral pressure when the test tube is inserted and taken out and clamped, affecting the positioning accuracy and reliability of a taking and placing cup, avoiding the failure of grabbing or falling due to insertion failure of a reaction cup, solving the problem that the included angle between the reaction cup and the axis of a cup seat cannot be too large, enabling the test tube to be inserted or separated from the cup seat in a vertical state when the test tube is not uniformly mixed, enabling the reagent to be more easily and reciprocally moved and uniformly mixed in a horizontal plane when the test tube is uniformly mixed, solving the problem that the included angle between the reaction cup and the cup seat is invariable, enabling liquid in the reaction cup to be more easily and reciprocally moved and uniformly mixed in the horizontal direction when the reaction cup is reciprocally swung, and solving the problem that noise is larger when the conventional uniform mixing structure is a rigid structure.
The foregoing description is only of the optional embodiments of the present invention, and is not intended to limit the scope of the invention, and all equivalent structural modifications made by the present description and accompanying drawings or direct/indirect application in other related technical fields are included in the scope of the present invention.