0.1 part by mass of U20 was scattered on the surface of 97.9 parts by mass of deionized water at room temperature, after sufficiently wetting, 2.0 parts by mass of glycine was scattered while rapidly stirring at 500rpm, and stirred for 5 minutes to dissolve uniformly, to finally obtain a U20 hydrogel composition which was colorless and transparent in appearance as a mobile gel, and the pH was measured to be 4.861, and the viscosity was measured to be 2242 mPas.

Example 2: preparation of gel compositions

0.2 part by mass of U20 was scattered on the surface of 97.8 parts by mass of deionized water at room temperature, after sufficiently wetting, 2.0 parts by mass of glycine was scattered while rapidly stirring at 500rpm, and stirred for 5 minutes to dissolve uniformly, to finally obtain a U20 hydrogel composition which was a colorless transparent semi-fluid gel in appearance, measured to have a pH of 4.568, and measured to have a viscosity of 12220 mPas.

Example 3: preparation of gel compositions

0.3 part by mass of U20 was scattered on the surface of 97.7 parts by mass of deionized water at room temperature, after sufficiently wetting, 2.0 parts by mass of glycine was scattered while rapidly stirring at 500rpm, and stirred for 5 minutes to dissolve uniformly, to finally obtain a U20 hydrogel composition which was colorless and transparent thick gel in appearance, measured at pH4.347, and measured as viscosity 19770 mPas.

Example 4: preparation of gel compositions

0.2 part by mass of U20 is sprinkled on the surface of 98.8 parts by mass of deionized water at room temperature, after fully wetting, 1.0 part by mass of glycine is sprinkled in the state of starting 500rpm rapid stirring, and stirred for 5 minutes until uniformly dissolved, finally obtaining the hydrogel composition of U20, the appearance is colorless transparent gel, the pH is measured to be 4.169, and the viscosity is measured to be 14780 mPas.

Example 5: preparation of gel compositions

0.2 part by mass of U20 is sprinkled on the surface of 99.3 parts by mass of deionized water at room temperature, after the deionized water is fully wetted, 0.5 part by mass of glycine is sprinkled in the state of starting to rapidly stir at 500rpm, and the mixture is stirred for 5 minutes until the glycine is uniformly dissolved, so that a U20 hydrogel composition is finally obtained, the appearance is colorless and transparent flowing gel, the pH value is measured to be 4.213, and the viscosity is measured to be 3000 mPas.

Example 6: preparation of gel compositions

0.3 part by mass of U20 was scattered on the surface of 99.2 parts by mass of deionized water at room temperature, after sufficiently wetting, 0.5 part by mass of glycine was scattered while rapidly stirring at 500rpm, and stirred for 5 minutes to dissolve uniformly, to finally obtain a U20 hydrogel composition which was colorless and transparent in appearance, measured as a mobile gel, pH4.086, and measured as viscosity 8330 mPas.

Example 7: preparation of gel compositions

0.3 part by mass of U20 was scattered on the surface of 98.7 parts by mass of deionized water at room temperature, after sufficiently wetting, 1 part by mass of glycine was scattered while rapidly stirring at 500rpm, and stirred for 5 minutes until uniformly dissolved, to finally obtain a U20 hydrogel composition which was colorless and transparent gel in appearance, measured pH4.189, and measured viscosity 14900 mPas.

Example 8: preparation of gel compositions

0.1 part by mass of U20 is scattered on the surface of 98.9 parts by mass of deionized water at room temperature, after the deionized water is fully wetted, 1 part by mass of glycine is scattered in the state of starting 500rpm and rapidly stirring for 5 minutes until the glycine is uniformly dissolved, and finally the hydrogel composition of U20 is obtained, the appearance is colorless and transparent flowing gel, the pH value is measured to be 4.673, and the viscosity is measured to be 1683mPa & s.

Example 9: preparation of gel compositions

0.1 part by mass of U20 is scattered on the surface of 96.9 parts by mass of deionized water at room temperature, after the deionized water is fully wetted, 3 parts by mass of glycine is scattered in the quick stirring state at 500rpm, the mixture is stirred for 5 minutes until the glycine is uniformly dissolved, finally, the hydrogel composition of U20 is obtained, the appearance is colorless and transparent flowing gel, the pH value is measured to be 4.774, and the viscosity is measured to be 4542mPa & s.

Example 10: preparation of gel compositions

0.2 part by mass of U20 is scattered on the surface of 96.8 parts by mass of deionized water at room temperature, after the deionized water is fully wetted, 3 parts by mass of glycine is scattered in the state of starting 500rpm and rapidly stirring for 5 minutes until the glycine is uniformly dissolved, and finally the hydrogel composition of U20 is obtained, the appearance of the gel is colorless and transparent, the pH value is measured to be 4.404, and the viscosity is measured to be 15570 mPas.

Example 11: preparation of gel compositions

Accurately weighing 2 parts by mass of glycerol at room temperature, adding 95.8 parts by mass of deionized water, and uniformly stirring and dispersing to obtain a glycerol-water mixed solution for later use.

0.2 part by mass of U20 was sprinkled on the surface of the glycerin-water mixed solution at room temperature, after sufficiently wetting, 2 parts by mass of glycine was sprinkled in the state of rapidly stirring at 500rpm, and stirred for 5 minutes to be dissolved uniformly, to finally obtain a U20 hydrogel composition which was a colorless transparent semi-fluid gel in appearance, measured pH4.578, and measured viscosity 13130 mPas.

Example 12: preparation of gel compositions

Accurately weighing 2 parts by mass of 1, 3-butanediol at room temperature, adding 95.8 parts by mass of deionized water, and uniformly stirring and dispersing to obtain a butanediol-water mixed solution for later use.

After 0.2 part by mass of U20 was sprinkled onto the surface of the butanediol-water mixed solution at room temperature and sufficiently wetted, 2 parts by mass of glycine was sprinkled while rapidly stirring at 500rpm and stirred for 5 minutes until uniformly dissolved, to finally obtain a U20 hydrogel composition which was a colorless and transparent semi-fluid gel in appearance, measured at pH4.526, and measured to have a viscosity of 12730 mPas.

Example 13: preparation of gel compositions

Accurately weighing 2 parts by mass of 1, 3-propanediol at room temperature, adding 95.8 parts by mass of deionized water, and uniformly stirring and dispersing to obtain a propanediol-water mixed solution for later use.

0.2 part by mass of U20 was sprinkled on the surface of the propylene glycol-water mixed solution at room temperature, after sufficiently wetting, 2 parts by mass of glycine was sprinkled in the rapidly stirred state at 500rpm, and stirred for 5 minutes to dissolve uniformly, to finally obtain a U20 hydrogel composition which was a colorless transparent semi-fluid gel in appearance, measured pH4.510, and measured viscosity 12420 mPas.

Example 14: preparation of gel compositions

0.2 part by mass of U10 was scattered on the surface of 97.8 parts by mass of deionized water at room temperature, after sufficiently wetting, 2.0 parts by mass of glycine was scattered while rapidly stirring at 500rpm, and stirred for 5 minutes to dissolve uniformly, to finally obtain a U10 hydrogel composition which was a colorless transparent semi-fluid gel in appearance, measured to have a pH of 4.564, and measured to have a viscosity of 13780 mPas.

Example 15: preparation of gel compositions

0.2 part by mass of U21 is scattered on the surface of 97.8 parts by mass of deionized water at room temperature, after the deionized water is fully wetted, 2.0 parts by mass of glycine is scattered in the state of starting 500rpm and rapidly stirring for 5 minutes until the glycine is uniformly dissolved, and finally, a U21 hydrogel composition which is colorless and transparent semi-flow gel is obtained, the pH value is measured to be 4.517, and the viscosity is measured to be 12560 mPas.

Example 16: preparation of gel compositions

0.2 part by mass of U30 is scattered on the surface of 97.8 parts by mass of deionized water at room temperature, after the deionized water is fully wetted, 2.0 parts by mass of glycine is scattered in the state of starting 500rpm and rapidly stirring for 5 minutes until the glycine is uniformly dissolved, and finally, a U30 hydrogel composition is obtained, the appearance of the gel is colorless and transparent, the pH value is measured to be 4.463, and the viscosity is measured to be 14360 mPas.

Example 17: preparation of gel compositions

At room temperature, 0.2 part by mass of TR-1 is scattered on the surface of 97.8 parts by mass of deionized water, after the deionized water is fully wetted, 2.0 parts by mass of glycine is scattered in the state of starting 500rpm and rapidly stirring for 5 minutes until the glycine is uniformly dissolved, and finally, the hydrogel composition of TR-1 is obtained, the appearance is colorless and transparent flowing gel, the pH value is measured to be 4.432, and the viscosity is measured to be 6560 mPas.

Example 18: preparation of gel compositions

And (2) scattering 0.2 part by mass of carbomer 980 onto the surface of 97.8 parts by mass of deionized water at room temperature, after fully wetting, scattering 2.0 parts by mass of glycine under the state of starting 500rpm and rapidly stirring, stirring for 5 minutes until the glycine is uniformly dissolved, finally obtaining the carbomer 980-based hydrogel composition, wherein the appearance of the carbomer 980-based hydrogel is colorless and transparent gel, and the viscosity is 15240mPa & s when the pH is measured to be 4.578.

Comparative example 1:

0.2 part by mass of U20 was sprinkled onto the surface of 99.8 parts by mass of deionized water at room temperature, and after sufficient wetting, 500rpm was turned on and stirring was rapidly carried out for 5 minutes, to finally obtain an aqueous gel dispersion composition containing a more U20-clumpy appearance.

Comparative example 2:

0.2 part by mass of U20 was sprinkled onto the surface of 99.8 parts by mass of deionized water at room temperature, and after sufficient wetting, 500rpm was turned on and stirring was rapidly carried out for 15 minutes, to finally obtain an aqueous gel dispersion composition containing a more U20-like floc appearance.

Comparative example 3:

0.2 part by mass of U20 was sprinkled onto the surface of 99.8 parts by mass of deionized water at room temperature, and after sufficient wetting, 500rpm was turned on and stirring was rapidly carried out for 30 minutes, to finally obtain an aqueous gel dispersion composition containing a more U20-clumpy appearance.

Comparative example 4:

0.2 part by mass of U20 is scattered on the surface of 99.8 parts by mass of deionized water at room temperature, after the deionized water is fully wetted, 5000rpm is started for homogenization for 3 minutes, and finally the aqueous gel dispersion system composition of U20 is obtained, the appearance of the aqueous gel dispersion system composition is fine, uniform and semi-transparent flowing liquid, and the upper surface layer of the aqueous gel dispersion system composition is provided with a plurality of bubbles.

From these experimental results the following conclusions can be drawn:

(1) it is demonstrated by examples 1 to 3 that amino acids (glycine as presented in the examples of the present invention) can help carbomer to disperse uniformly and thicken rapidly, glycine has obvious thickening effect on carbomer gel dispersions with different concentrations under the condition that the proportion of glycine is not changed, and the thickening effect depends on the actual concentration of carbomer.

(2) The group of references of example 2, example 4, example 5 and example 10, the group of references of example 1, example 8 and example 9, and the group of references of example 3, example 6 and example 7 respectively show that the viscosity of the gel is also influenced by the different addition ratios of glycine under the condition of constant carbomer concentration, namely, the higher the glycine ratio is, the higher the viscosity of the gel is when the carbomer concentration is the same; and the same concentration of glycine, the concentration of carbomer is a critical factor in affecting the final viscosity of the gel composition.

(4) Examples 11 to 13 show that amino acid thickening carbomers are also suitable for use in the alcohol-hydrogel system of carbomers, and that when carbomers are dispersed in a mixed solution of glycerin-water, butylene glycol-water and propylene glycol-water, a gel composition of the present invention can be obtained by adding glycine.

(5) Examples 14-18 illustrate that the amino acids described in the present patent (glycine as described in the examples) can help the carbomer to rapidly swell, disperse and thicken, and have thickening effects and universality for different types of carbomers.

(6) Comparative examples 1 to 3 show that the carbomer dispersion alone does not achieve rapid and uniform dispersion of the carbomer without the addition of glycine, and that even if the stirring dispersion time is increased, the desired effect is not achieved at all, and certainly there is no appearance that the carbomer dispersion can be swelled into a gel having a certain viscosity.

(7) The comparison example 4 shows that, although the high-energy mechanical external force action such as homogeneous shearing can help carbomer to realize the uniform dispersion process in water, the high energy consumption is required, and the homogeneous shearing causes more bubbles to be generated in the hydrogel dispersion system, so that the defoaming process is required to be additionally carried out, and the production steps are complicated. In addition, the homogenization process merely forms the carbomer aqueous dispersion into a uniform, translucent, fluid liquid and does not help to form a viscous gel, so the rapid thickening and swelling process described in the present invention is not realized.

It can be seen from the above experiments that the process of thickening acrylate polymers with amino acids is different from the prior art of alkali neutralization. During the neutralization thickening process, the pH will go from acidic to neutral or alkaline while forming a gel. In contrast, the process pH for amino acid thickening of acrylic polymers of the present application is still in the acidic range.

The composition containing the acrylate polymer and the amino acid can form a uniform and transparent gel composition, while the acrylate polymer in the prior art needs to be homogenized into a uniform and transparent dispersion system, and then added with alkali to neutralize and viscosity to form gel.

The invention has the advantages of reducing homogenization steps and alkali neutralization, reducing energy consumption and reducing cost.

Application example

The compositions of the present invention may be used as an intermediate material in the preparation of personal care products, preferably cosmetic compositions, including but not limited to the preparation of products in the form of creams, lotions, gels, lotions, serums, masks, eye creams, aerosols (cleansing foams), sprays, body washes, massage oils, facial cleansers, and the like.

The weight percentage of the composition of the present invention in the personal care product is 0.0001% to 20% (w/w); preferably 0.001-10% (w/w); more preferably 0.001-5% (w/w); most preferably 0.01% to 5% (w/w).

The following are specific examples of the use of the gel compositions obtained in examples 2-8 in personal care products, as well as the formulations and methods of preparation of these dosage forms. The specific application examples are as follows:

application example 1: preparation of astringent

Application example 2: preparation of essence

Application example 3: preparation of the emulsion

Application example 4: preparation of gel mask

Application example 5: preparation of face cream

Claims

1. A gel composition comprising an acrylate polymer and an amino acid, wherein the gel composition comprises at least 0.2 wt% of the acrylate polymer, based on the total weight of the composition.

2. The gel composition of claim 1, wherein the amino acid is present in an amount of 1 to 5 wt%.

3. The gel composition of claim 1, wherein the weight ratio of the acrylate polymer to the amino acid in the gel composition is from 1:50 to 1: 2.

4. The gel composition of claim 3, wherein the weight ratio of the acrylate polymer to the amino acid in the gel composition is from 1:30 to 1: 5.

5. The gel composition of any one of claims 1-4, wherein the acrylate-based polymer is selected from the group consisting of: carbomer, acrylic ester/C10-30 alkanol acrylic ester cross-linked copolymer, acrylic acid (ester)/acrylamide copolymer, acrylic acid (ester)/ammonium methacrylate copolymer, acrylic acid (ester)/C12-22 alkanol methacrylate copolymer, acrylic acid (ester) cross-linked polymer, acrylic acid (ester)/ethylhexyl acrylate/styrene copolymer, acrylic acid (ester)/hydroxy ester acrylic acid (ester) copolymer, acrylic acid (ester)/octyl acrylamide copolymer, acrylic acid (ester)/tert-butyl acrylamide copolymer, acrylic acid (ester)/urethane copolymer, acrylic acid (ester)/octyl acrylamide copolymer, acrylic acid (ester)/TDI/trimethylolpropane copolymer, Acrylic acid (ester)/VA copolymer, acrylic acid (ester)/VA crosslinked polymer, acrylic acid (ester)/vinyl isodecanoate crosslinked polymer, acrylic acid (ester)/vinyl neodecanoate crosslinked polymer, acrylic acid (ester)/VP copolymer, acrylic acid (ester) copolymer ammonium, acrylic acid (ester)/acrylamide copolymer potassium salt, acrylic acid (ester)/C10-30 alcohol acrylate crosslinked polymer potassium salt.

6. The gel composition of any one of claims 1-4, wherein the amino acid is an alpha amino acid from C3-C6.

7. The gel composition of claim 6, wherein the alpha amino acid is selected from the group consisting of: alanine, asparagine, aspartic acid, methionine, glutamine, glutamic acid, glycine, isoleucine, leucine, cysteine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, valine.

8. A gel composition according to any one of claims 1 to 4 wherein the pH of the composition is from 4 to 5.

9. A process for preparing a gel composition according to any one of claims 1 to 8, comprising the steps of:

(a) dispersing an acrylate polymer into a personal care art-acceptable carrier;

or

(a) Dispersing an alpha amino acid in a personal care art-acceptable carrier;

10. The method of claim 9, wherein the stirring state is a state in which the composition is stirred to a uniform transparent gel.

11. A personal care product comprising the gel composition of any one of claims 1-10.

12. The personal care product of claim 11, wherein the personal care product is selected from the group consisting of: astringent, essence, jelly, lotion, and cream.