技术领域Technical field
本发明涉及医用器具技术领域，具体涉及到一种用于皮肤组织液穿刺的微针装置。The present invention relates to the technical field of medical instruments, and in particular to a microneedle device used for puncturing skin tissue fluid.
背景技术Background technique
组织液是存在细胞间隙的体液，是人体体重的15％-25％，形成了体内含量最多的一种液体。组织液与血液可以通过血管壁进行物质交换，这导致在血液中的许多标志物，如蛋白、核酸、代谢物等也广泛存在于组织液中。因此，抽取组织液进行疾病标志物相关的分析具有良好的前景。Interstitial fluid is the body fluid that exists in the intercellular space. It accounts for 15%-25% of the body weight and forms the most abundant liquid in the body. Interstitial fluid and blood can exchange substances through the blood vessel wall, which results in many markers in the blood, such as proteins, nucleic acids, metabolites, etc., also widely present in the interstitial fluid. Therefore, extracting tissue fluid for analysis of disease markers has good prospects.
由于组织液大部分都在皮肤的真皮层，目前提取组织液的方法是使用微针。Miller等人提出了由5个1500微米形成的微针直线阵列，每只微针的直径为0.108mm，并且5只微针并排成一条线。每只微针的末端连接了一个玻璃毛细管，通过毛细管作用将组织液吸入管中。该微针阵列成功在2小时内提取16微升的组织液。Samant等人也提出了类似由5个微针形成的微针直线阵列，但是不同的是此阵列的微针长度为200微米。组织液的提取是通过使用真空泵在3分钟内从0kPa慢慢增加至-50kPa的负压，成功在20分钟提取2.3微升的组织液。Since most of the tissue fluid is in the dermis layer of the skin, the current method of extracting tissue fluid is to use microneedles. Miller et al. proposed a linear array of five 1500-micron microneedles, each with a diameter of 0.108mm, and the five microneedles were arranged side by side in a line. The end of each microneedle is connected to a glass capillary tube, which draws tissue fluid into the tube through capillary action. The microneedle array successfully extracted 16 microliters of tissue fluid within 2 hours. Samant et al. also proposed a linear array of microneedles similar to that formed by five microneedles, but the difference is that the length of the microneedles in this array is 200 microns. The tissue fluid was extracted by using a vacuum pump to slowly increase the negative pressure from 0kPa to -50kPa within 3 minutes, and 2.3 microliters of tissue fluid was successfully extracted in 20 minutes.
现有技术存在的问题是都使用单一长度的微针，这种设计忽略了组织液深度在不同人的异质性，这会影响该技术的可靠性与普遍性。此外，现有的技术均需要昂贵的设备，如真空泵，导致整体技术成本过高且不方便携带。最后，由于需要较长的提取时间或使用真空泵，现有的技术会对皮肤造成显著的伤痕，往往需要几周的时间方可恢复。The problem with existing technologies is that they all use microneedles of a single length. This design ignores the heterogeneity of tissue fluid depth in different people, which will affect the reliability and universality of the technology. In addition, existing technologies require expensive equipment such as vacuum pumps, making the overall technology cost too high and inconvenient to carry. Finally, existing techniques can cause significant scarring to the skin, often requiring weeks to recover, due to the long extraction times or use of vacuum pumps required.
发明内容Contents of the invention
本发明的目的在于至少解决现有技术中存在的技术问题之一，提供一种用于皮肤组织液穿刺的微针装置。The purpose of the present invention is to solve at least one of the technical problems existing in the prior art and provide a microneedle device for puncturing skin tissue fluid.
为实现上述目的，本发明采用的技术方案如下：一种用于皮肤组织液穿刺的微针装置，包括顶盖、外壳、布防装置、部署装置、针膛、针头，所述顶盖、布防装置、针膛从上至下依次设置在外壳内，所述部署装置设置在外壳的侧部，所述针头设置在外壳的底部并与针膛连接，所述顶盖可上下活动的设置在外壳内，所述针膛的侧部设置有凸出部，所述外壳的侧部设置有与凸出部配合的凹槽，所述布防装置分别与顶盖、针膛连接，所述布防装置用于在顶盖的活动作用下带动针膛向上活动，使凸出部卡接于凹槽中，所述针头的端部设置有若干长度不同的微针，所述外壳的端部设置有用于对微针活动进行限位的端盖，所述部署装置用于驱动凸出部向内活动以脱离凹槽且布防装置驱动针膛和针头向下活动，使微针伸出端盖。In order to achieve the above object, the technical solution adopted by the present invention is as follows: a microneedle device for skin tissue fluid puncture, including a top cover, a shell, an arming device, a deployment device, a needle chamber, and a needle. The top cover, arming device, The needle chambers are arranged in the casing from top to bottom, the deployment device is arranged on the side of the casing, the needle is arranged at the bottom of the casing and connected to the needle chamber, and the top cover is movable up and down in the casing, The side of the needle chamber is provided with a protruding portion, the side of the housing is provided with a groove that matches the protruding portion, the arming device is connected to the top cover and the needle chamber respectively, and the arming device is used to The movement of the top cover drives the needle chamber to move upward, so that the protruding portion is engaged in the groove. The end of the needle is provided with a number of microneedles of different lengths, and the end of the shell is provided with a microneedle for adjusting the microneedles. The end cap is movable and limited, the deployment device is used to drive the protrusion to move inward to escape from the groove, and the arming device drives the needle chamber and the needle head to move downward, so that the microneedle extends out of the end cap.
进一步的，所述布防装置包括布防杆和布防弹簧，所述布防杆可转动的设置在外壳内，所述布防杆左端与顶盖连接、右端与针膛连接，所述布防杆能够在顶盖的上下活动作用下转动并带动针膛上下活动，所述布防弹簧分别与布防杆、针膛连接，用于使布防杆复位。Further, the arming device includes an arming rod and an arming spring. The arming rod is rotatably arranged in the casing. The left end of the arming rod is connected to the top cover and the right end is connected to the needle bore. The arming rod can be mounted on the top cover. It rotates under the action of the up and down movement and drives the needle chamber to move up and down. The arming spring is connected to the arming rod and the needle chamber respectively, and is used to reset the arming rod.
进一步的，所述顶盖的侧部设置有安全鞘，所述外壳内设置有与安全鞘配合的安全槽。Further, a safety sheath is provided on the side of the top cover, and a safety groove that matches the safety sheath is provided in the housing.
进一步的，所述顶盖可转动的设置在外壳中，转动所述顶盖以使安全鞘移出或移进安全槽。Further, the top cover is rotatably arranged in the housing, and the top cover is rotated to move the safety sheath out of or into the safety groove.
进一步的，所述部署装置包括部署按钮和部署弹簧，所述部署弹簧分别与部署按钮、外壳连接，用于使部署按钮复位，所述部署按钮上设置有可在凹槽内活动的顶出部。Further, the deployment device includes a deployment button and a deployment spring. The deployment spring is connected to the deployment button and the housing respectively, and is used to reset the deployment button. The deployment button is provided with an ejection part that can move in the groove. .
进一步的，所述端盖可拆卸的设置在外壳的端部上。Further, the end cap is detachably provided on the end of the housing.
进一步的，所述针头包括持针部，所述微针固定在持针部的底部，所述持针部的上部设置有与针膛的底端配合的卡槽。Furthermore, the needle head includes a needle-holding part, the microneedle is fixed on the bottom of the needle-holding part, and the upper part of the needle-holding part is provided with a slot that matches the bottom end of the needle chamber.
进一步的，还包括卸针装置，所述卸针装置包括卸针轴和卸针弹簧，所述卸针轴套设在针膛的外侧，所述卸针轴能够在顶盖的带动下向下活动至与针头抵接，以使针头从针膛上卸下，所述卸针弹簧分别与卸针轴、外壳连接，用于使卸针轴复位。Further, it also includes a needle unloading device. The needle unloading device includes a needle unloading shaft and a needle unloading spring. The needle unloading shaft is sleeved on the outside of the needle chamber. The needle unloading shaft can be driven downward by the top cover. It moves until it comes into contact with the needle, so that the needle is removed from the needle chamber. The needle-removing spring is connected to the needle-removing shaft and the housing respectively, and is used to reset the needle-removing shaft.
进一步的，所述端盖上设置有环形标记。Further, the end cap is provided with an annular mark.
进一步的，所述微针设置有3个，3个所述微针排列成圆形微针阵列，3个所述微针的长度分别为300微米、400微米、500微米。Further, there are three microneedles arranged in a circular microneedle array, and the lengths of the three microneedles are respectively 300 microns, 400 microns, and 500 microns.
本发明的有益效果：由上述对本发明的描述可知，与现有技术相比，本发明的用于皮肤组织液穿刺的微针装置包括顶盖、外壳、布防装置、部署装置、针膛、针头，所述顶盖、布防装置、针膛从上至下依次设置在外壳内，所述部署装置设置在外壳的侧部，所述针头设置在外壳的底部并与针膛连接，所述顶盖可上下活动的设置在外壳内，所述针膛的侧部设置有凸出部，所述外壳的侧部设置有与凸出部配合的凹槽，具体使用时，先将针头安装在针膛上，向下活动顶盖，布防装置带动针膛向上活动，使凸出部卡接于凹槽中，此时布防装置进入准备状态，将端盖接触人体皮肤，通过部署装置驱动凸出部向内活动以脱离凹槽，布防装置驱动针膛和针头向下活动，微针伸出端盖刺破人体皮肤，释放组织液至皮肤表面，以进行组织液的收集，本发明使用了不同长度的微针，提高了穿刺最多组织液的地方的概率，从而提高了提取组织液的效率；此外，本发明通过顶盖、布防装置和部署装置等配合进行刺破皮肤作用，使用较为方便，提取效率得到提升，使得所需的提取时间也会相对应减少，这导致微针插在皮肤的时间减少而不会导致任何皮肤的显著伤痕，本发明的微针阵列被安置在一个简单而便携的微针装置中，使得本发明的成本低且方便携带。Beneficial effects of the present invention: From the above description of the present invention, it can be seen that compared with the prior art, the microneedle device for skin tissue fluid puncture of the present invention includes a top cover, a shell, an arming device, a deployment device, a needle chamber, and a needle. The top cover, the arming device, and the needle chamber are arranged in the casing in sequence from top to bottom, the deployment device is arranged on the side of the casing, the needle is arranged at the bottom of the casing and connected to the needle chamber, and the top cover can It is arranged in a casing that can move up and down. The side of the needle chamber is provided with a protruding portion. The side of the housing is provided with a groove that matches the protruding portion. When using it, first install the needle on the needle chamber. , move the top cover downward, and the arming device drives the needle chamber to move upward, so that the protruding part is locked in the groove. At this time, the arming device enters the ready state, contacts the end cover with human skin, and drives the protruding part inward through the deployment device The arming device drives the needle chamber and the needle to move downward. The microneedle extends the end cover to pierce the human skin and releases tissue fluid to the skin surface for collection of tissue fluid. The present invention uses microneedles of different lengths. It increases the probability of puncturing the place with the most tissue fluid, thereby improving the efficiency of extracting tissue fluid; in addition, the present invention punctures the skin through the cooperation of the top cover, the arming device and the deployment device, which is more convenient to use and the extraction efficiency is improved, so that all The required extraction time will also be correspondingly reduced, which results in a reduction in the time the microneedle is inserted into the skin without causing any significant scars on the skin. The microneedle array of the present invention is placed in a simple and portable microneedle device, so that The invention has low cost and is easy to carry.
附图说明Description of the drawings
图1为本发明优选实施例中一种用于皮肤组织液穿刺的微针装置在不使用状态下的结构示意图；Figure 1 is a schematic structural diagram of a microneedle device for skin tissue fluid puncture in a non-use state in a preferred embodiment of the present invention;
图2为本发明优选实施例中一种用于皮肤组织液穿刺的微针装置在布防装置进入准备状态下的结构示意图；Figure 2 is a schematic structural diagram of a microneedle device used for skin tissue fluid puncture in a preferred embodiment of the present invention when the arming device enters a ready state;
图3为本发明优选实施例中一种用于皮肤组织液穿刺的微针装置在使用状态下的结构示意图；Figure 3 is a schematic structural diagram of a microneedle device used for skin tissue fluid puncture in a preferred embodiment of the present invention in use;
图4为本发明优选实施例中针头的结构示意图；Figure 4 is a schematic structural diagram of a needle in a preferred embodiment of the present invention;
附图标记：1、顶盖；2、外壳；3、布防装置；4、部署装置；5、针膛；6、针头；7、卸针装置；11、安全鞘；21、凹槽；22、端盖；23、安全槽；24、环形标记；31、布防杆；32、布防弹簧；41、部署按钮；42、部署弹簧；43、顶出部；51、突出部；61、微针；62、持针部；71、卸针轴；72、卸针弹簧。Reference signs: 1. Top cover; 2. Shell; 3. Arming device; 4. Deployment device; 5. Needle chamber; 6. Needle; 7. Needle removal device; 11. Safety sheath; 21. Groove; 22. End cap; 23. Safety slot; 24. Ring mark; 31. Arming rod; 32. Arming spring; 41. Deployment button; 42. Deployment spring; 43. Ejection part; 51. Protruding part; 61. Microneedle; 62 , needle holding part; 71, needle unloading shaft; 72, needle unloading spring.
具体实施方式Detailed ways
下面将结合本发明实施例中的附图，对本发明中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅是本发明的一部分实施例，而不是全部的实施例。The technical solutions in the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some of the embodiments of the present invention, not all of them.
在本发明的描述中，需要说明的是，除非另有明确的规定和限定，术语“相连”、“连接”应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或一体地连接；可以是机械连接，也可以是电连接；可以是直接相连，也可以通过中间媒介间接相连。对于本领域的普通技术人员而言，可以具体情况理解上述术语在本发明中的具体含义。In the description of the present invention, it should be noted that, unless otherwise clearly stated and limited, the terms "connected" and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection. Ground connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood on a case-by-case basis.
参照图1-4所示，本发明的优选实施例，一种用于皮肤组织液穿刺的微针装置，包括顶盖1、外壳2、布防装置3、部署装置4、针膛5、针头6，所述顶盖1、布防装置3、针膛5从上至下依次设置在外壳2内，所述部署装置4设置在外壳2的侧部，所述针头6设置在外壳2的底部并与针膛5连接，所述顶盖1可上下活动的设置在外壳2内，所述针膛5的侧部设置有凸出部51，所述外壳2的侧部设置有与凸出部51配合的凹槽21，所述布防装置3分别与顶盖1、针膛5连接，所述布防装置3用于在顶盖1的活动作用下带动针膛5向上活动，使凸出部51卡接于凹槽21中，所述针头6的端部设置有若干长度不同的微针61，所述外壳2的端部设置有用于对微针61活动进行限位的端盖22，所述部署装置4用于驱动凸出部51向内活动以脱离凹槽21且布防装置3驱动针膛5和针头6向下活动，使微针61伸出端盖22。Referring to Figures 1-4, a preferred embodiment of the present invention, a microneedle device for skin tissue fluid puncture, includes a top cover 1, a shell 2, an arming device 3, a deployment device 4, a needle chamber 5, and a needle 6, The top cover 1, the arming device 3, and the needle chamber 5 are arranged in the housing 2 from top to bottom, the deployment device 4 is arranged on the side of the housing 2, and the needle 6 is arranged at the bottom of the housing 2 and connected with the needle. The top cover 1 is connected to the needle chamber 5, and the top cover 1 is movable up and down in the housing 2. The side of the needle chamber 5 is provided with a protruding portion 51, and the side of the housing 2 is provided with a protruding portion 51 that cooperates with the protruding portion 51. Groove 21, the arming device 3 is connected to the top cover 1 and the needle chamber 5 respectively. The arming device 3 is used to drive the needle chamber 5 to move upward under the movement of the top cover 1, so that the protruding portion 51 is engaged with the groove 21. In the groove 21, the end of the needle 6 is provided with a number of microneedles 61 of different lengths. The end of the housing 2 is provided with an end cap 22 for limiting the movement of the microneedles 61. The deployment device 4 It is used to drive the protrusion 51 to move inward to disengage from the groove 21 and the arming device 3 to drive the needle chamber 5 and the needle 6 to move downward so that the microneedle 61 extends out of the end cap 22 .
本发明的用于皮肤组织液穿刺的微针装置包括顶盖1、外壳2、布防装置3、部署装置4、针膛5、针头6，所述顶盖1、布防装置3、针膛5从上至下依次设置在外壳2内，所述部署装置4设置在外壳2的侧部，所述针头6设置在外壳2的底部并与针膛5连接，所述顶盖1可上下活动的设置在外壳2内，所述针膛5的侧部设置有凸出部51，所述外壳2的侧部设置有与凸出部51配合的凹槽21，具体使用时，先将针头6安装在针膛5上，向下活动顶盖1，布防装置3带动针膛5向上活动，使凸出部51卡接于凹槽21中，此时布防装置3进入准备状态，将端盖22接触人体皮肤，通过部署装置4驱动凸出部51向内活动以脱离凹槽21，布防装置3驱动针膛5和针头6向下活动，微针61伸出端盖22刺破人体皮肤，释放组织液至皮肤表面，以进行组织液的收集，本发明使用了不同长度的微针61，提高了穿刺最多组织液的地方的概率，从而提高了提取组织液的效率；此外，本发明通过顶盖1、布防装置3和部署装置4等配合进行刺破皮肤作用，使用较为方便，提取效率得到提升，使得所需的提取时间也会相对应减少，这导致微针61插在皮肤的时间减少而不会导致任何皮肤的显著伤痕，本发明的微针61阵列被安置在一个简单而便携的微针装置中，使得本发明的成本低且方便携带。The microneedle device for skin tissue fluid puncture of the present invention includes a top cover 1, a shell 2, an arming device 3, a deployment device 4, a needle chamber 5, and a needle 6. The top cover 1, the arming device 3, and the needle chamber 5 are viewed from above. The deployment device 4 is arranged on the side of the casing 2. The needle 6 is arranged on the bottom of the casing 2 and connected to the needle chamber 5. The top cover 1 is movable up and down. In the housing 2, the side of the needle chamber 5 is provided with a protruding portion 51, and the side of the housing 2 is provided with a groove 21 that matches the protruding portion 51. During specific use, the needle 6 is first installed on the needle. On the chamber 5, move the top cover 1 downward, and the arming device 3 drives the needle chamber 5 to move upward, so that the protruding part 51 is engaged in the groove 21. At this time, the arming device 3 enters the ready state, and the end cover 22 contacts the human skin. , the deployment device 4 drives the protrusion 51 to move inward to escape from the groove 21, the arming device 3 drives the needle chamber 5 and the needle 6 to move downward, the microneedle 61 extends out of the end cap 22 to pierce the human skin, releasing tissue fluid to the skin surface to collect tissue fluid. The present invention uses microneedles 61 of different lengths, which increases the probability of puncturing the place with the most tissue fluid, thereby improving the efficiency of extracting tissue fluid; in addition, the present invention uses the top cover 1, the arming device 3 and the The deployment device 4 and the like cooperate to puncture the skin, which is more convenient to use, the extraction efficiency is improved, and the required extraction time is correspondingly reduced, which results in a reduction in the time the microneedles 61 are inserted into the skin without causing any skin damage. Significantly, the microneedle 61 array of the present invention is placed in a simple and portable microneedle device, making the present invention low-cost and portable.
作为本发明的优选实施例，其还可具有以下附加技术特征：As a preferred embodiment of the present invention, it may also have the following additional technical features:
在本实施例中，所述布防装置3包括布防杆31和布防弹簧32，所述布防杆31可转动的设置在外壳2内，所述布防杆31左端与顶盖1连接、右端与针膛5连接，所述布防杆31能够在顶盖1的上下活动作用下转动并带动针膛5上下活动，所述布防弹簧32分别与布防杆31、针膛5连接，用于使布防杆31复位。布防装置3包括布防杆31和布防弹簧32，所述布防杆31可转动的设置在外壳2内，所述布防杆31左端与顶盖1连接、右端与针膛5连接，布防装置3在进入准备状态时，向下活动顶盖1，布防杆31左端向下活动，且布防杆31转动，布防杆31右端带动针膛5向上活动，布防弹簧32被压缩，直到凸出部51卡接于凹槽21中，使本发明进入准备使用状态。In this embodiment, the arming device 3 includes an arming rod 31 and an arming spring 32. The arming rod 31 is rotatably arranged in the housing 2. The left end of the arming rod 31 is connected to the top cover 1, and the right end is connected to the needle chamber. 5 connection, the arming rod 31 can rotate under the action of the up and down movement of the top cover 1 and drive the needle chamber 5 to move up and down. The arming spring 32 is connected to the arming rod 31 and the needle chamber 5 respectively, and is used to reset the arming rod 31 . The arming device 3 includes an arming rod 31 and an arming spring 32. The arming rod 31 is rotatably arranged in the housing 2. The left end of the arming rod 31 is connected to the top cover 1 and the right end is connected to the needle chamber 5. The arming device 3 enters the In the ready state, move the top cover 1 downward, the left end of the arming lever 31 moves downward, and the arming lever 31 rotates, the right end of the arming lever 31 drives the needle chamber 5 to move upward, and the arming spring 32 is compressed until the protrusion 51 is engaged with In the groove 21, the invention enters the ready-to-use state.
在本实施例中，所述顶盖1的侧部设置有安全鞘11，所述外壳2内设置有与安全鞘11配合的安全槽23，所述顶盖1可转动的设置在外壳2中，转动所述顶盖1以使安全鞘11移出或移进安全槽23。在顶盖1的侧部设置安全鞘11且外侧内设置安全槽23，当不需要使用时，将安全鞘11卡在安全槽23中，避免顶盖1活动，当需要使用时，转动顶盖1使安全鞘11从安全槽23中移出，以便上下活动顶盖1。In this embodiment, a safety sheath 11 is provided on the side of the top cover 1 , and a safety groove 23 matching the safety sheath 11 is provided in the housing 2 . The top cover 1 is rotatably provided in the housing 2 , rotate the top cover 1 to move the safety sheath 11 out of or into the safety groove 23 . A safety sheath 11 is provided on the side of the top cover 1 and a safety groove 23 is provided on the outside. When it is not needed, the safety sheath 11 is stuck in the safety groove 23 to prevent the top cover 1 from moving. When it is needed, rotate the top cover. 1. Remove the safety sheath 11 from the safety groove 23 so that the top cover 1 can be moved up and down.
在本实施例中，所述部署装置4包括部署按钮41和部署弹簧42，所述部署弹簧42分别与部署按钮41、外壳2连接，用于使部署按钮41复位，所述部署按钮41上设置有可在凹槽21内活动的顶出部43。部署装置4包括部署按钮41和部署弹簧42，部署弹簧42分别与部署按钮41、外壳2连接，部署按钮41上设置有可在凹槽21内活动的顶出部43，在布防装置3进入准备状态后，将本发明的端盖22按在人体皮肤上，按压部署按钮41，顶出部43将突出部从凹槽21中顶出，受压的布防弹簧32驱动针膛5和针头6向下活动，微针61穿出端盖22，刺破皮肤。In this embodiment, the deployment device 4 includes a deployment button 41 and a deployment spring 42. The deployment spring 42 is connected to the deployment button 41 and the housing 2 respectively, and is used to reset the deployment button 41. The deployment button 41 is provided with There is an ejection part 43 that is movable in the groove 21. The deployment device 4 includes a deployment button 41 and a deployment spring 42. The deployment spring 42 is connected to the deployment button 41 and the housing 2 respectively. The deployment button 41 is provided with an ejection part 43 that can move in the groove 21. When the arming device 3 enters preparation After the state is reached, press the end cap 22 of the present invention on the human skin, press the deployment button 41, the ejection part 43 will eject the protrusion from the groove 21, and the compressed arming spring 32 drives the needle chamber 5 and the needle 6 to When the microneedle 61 is moved down, the microneedle 61 penetrates the end cap 22 and punctures the skin.
在本实施例中，所述端盖22可拆卸的设置在外壳2的端部上。端盖22可拆卸的设置在外壳2的端部上，以便拆下端盖22对使用过的针头6进行更换。In this embodiment, the end cap 22 is detachably provided on the end of the housing 2 . The end cap 22 is detachably disposed on the end of the housing 2 so that the used needle 6 can be replaced by removing the end cap 22 .
在本实施例中，所述针头6包括持针部62，所述微针61固定在持针部62的底部，所述持针部62的上部设置有与针膛5的底端配合的卡槽。针头6包括持针部62，通过持针部62对微针61进行固定，在持针部62的上部设置与针膛5的底端配合的卡槽，以通过卡槽将针头6安装在针膛5上。In this embodiment, the needle 6 includes a needle holding part 62 , the microneedles 61 are fixed on the bottom of the needle holding part 62 , and the upper part of the needle holding part 62 is provided with a clip that matches the bottom end of the needle chamber 5 groove. The needle 6 includes a needle holding part 62, through which the microneedle 61 is fixed. A slot is provided on the upper part of the needle holding part 62 to match the bottom end of the needle chamber 5, so that the needle 6 can be installed on the needle through the slot. Chamber 5 on.
在本实施例中，还包括卸针装置7，所述卸针装置7包括卸针轴71和卸针弹簧72，所述卸针轴71套设在针膛5的外侧，所述卸针轴71能够在顶盖1的带动下向下活动至与针头6抵接，以使针头6从针膛5上卸下，所述卸针弹簧72分别与卸针轴71、外壳2连接，用于使卸针轴71复位。本发明还包括卸针装置7，卸针装置7包括卸针轴71和卸针弹簧72，所述卸针轴71套设在针膛5的外侧，在针头6使用过后，需要取下更换，将顶盖1向下活动至卸针轴71位置，继续向下活动顶盖1，使卸针轴71向下活动，卸针轴71将针头6从针膛5上顶出取下，不需要使用者手动取下针头6，较为安全。In this embodiment, a needle unloading device 7 is also included. The needle unloading device 7 includes a needle unloading shaft 71 and a needle unloading spring 72. The needle unloading shaft 71 is sleeved on the outside of the needle chamber 5. The needle unloading shaft 71 71 can move downwards driven by the top cover 1 until it abuts the needle 6, so that the needle 6 can be removed from the needle chamber 5. The needle removal spring 72 is connected to the needle removal shaft 71 and the housing 2 respectively, for Reset the needle unloading shaft 71. The present invention also includes a needle unloading device 7. The needle unloading device 7 includes a needle unloading shaft 71 and a needle unloading spring 72. The needle unloading shaft 71 is sleeved on the outside of the needle chamber 5. After the needle 6 is used, it needs to be removed and replaced. Move the top cover 1 downward to the position of the needle unloading shaft 71, and continue to move the top cover 1 downward to move the needle unloading shaft 71 downward. The needle unloading shaft 71 will eject the needle 6 from the needle chamber 5 and remove it. No need The user manually removes the needle 6, which is safer.
在本实施例中，所述端盖22上设置有环形标记24。端盖22上设置有环形标记24，通过环形标记24标记人体皮肤被刺入的地方。In this embodiment, the end cap 22 is provided with an annular mark 24 . An annular mark 24 is provided on the end cap 22, and the annular mark 24 marks the place where the human skin is penetrated.
在本实施例中，所述微针61设置有3个，3个所述微针61排列成圆形微针阵列，3个所述微针61的长度分别为300微米、400微米、500微米。本发明使用了三个不同长度的微针61，分别为300微米、400微米和500微米，并形成一个圆形微针阵列，考虑到组织液深度在不同人的异质性，此设计提高了穿刺最多组织液地方的概率，从而提高了提取组织液的效率。In this embodiment, there are three microneedles 61 arranged in a circular microneedle array, and the lengths of the three microneedles 61 are respectively 300 microns, 400 microns, and 500 microns. . The present invention uses three microneedles 61 of different lengths, respectively 300 microns, 400 microns and 500 microns, and forms a circular microneedle array. Taking into account the heterogeneity of tissue fluid depth in different people, this design improves puncture efficiency. The probability of finding the most tissue fluid, thereby improving the efficiency of extracting tissue fluid.
在不出现冲突的前提下，本领域技术人员可以将上述附加技术特征自由组合以及叠加使用。On the premise that no conflict occurs, those skilled in the art can freely combine and superimpose the above additional technical features.
可以理解，本发明是通过一些实施例进行描述的，本领域技术人员知悉的，在不脱离本发明的精神和范围的情况下，可以对这些特征和实施例进行各种改变或等效替换。另外，在本发明的教导下，可以对这些特征和实施例进行修改以适应具体的情况及材料而不会脱离本发明的精神和范围。因此，本发明不受此处所公开的具体实施例的限制，所有落入本申请的权利要求范围内的实施例都属于本发明所保护的范围内。It is understood that the present invention has been described through some embodiments. Those skilled in the art know that various changes or equivalent substitutions can be made to these features and embodiments without departing from the spirit and scope of the present invention. In addition, the features and embodiments may be modified to adapt a particular situation and material to the teachings of the invention without departing from the spirit and scope of the invention. Therefore, the present invention is not limited to the specific embodiments disclosed here, and all embodiments falling within the scope of the claims of the present application are within the scope of protection of the present invention.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111340906.4ACN114081538B (en) | 2021-11-12 | 2021-11-12 | Microneedle device for skin tissue fluid puncture |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111340906.4ACN114081538B (en) | 2021-11-12 | 2021-11-12 | Microneedle device for skin tissue fluid puncture |
| Publication Number | Publication Date |
|---|---|
| CN114081538A CN114081538A (en) | 2022-02-25 |
| CN114081538Btrue CN114081538B (en) | 2023-09-15 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111340906.4AActiveCN114081538B (en) | 2021-11-12 | 2021-11-12 | Microneedle device for skin tissue fluid puncture |
| Country | Link |
|---|---|
| CN (1) | CN114081538B (en) |
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| TA01 | Transfer of patent application right | Effective date of registration:20230328 Address after:330000 no.1688 Meiling Avenue, Wanli District, Nanchang City, Jiangxi Province Applicant after:JIANGXI University OF TRADITIONAL CHINESE MEDICINE Address before:C20, 7th floor, CITIC Fuji pharmaceutical Valley, No. 898, Nanjing East Road, Qingshanhu District, Nanchang City, Jiangxi Province, 330000 Applicant before:Jiangxi weirun Xinjing Technology Co.,Ltd. | |
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