技术领域Technical Field
本发明涉及医疗器械技术领域，具体涉及一种血栓取出装置。The present invention relates to the technical field of medical devices, and in particular to a thrombus removal device.
背景技术Background technique
急性缺血性脑卒中是由于脑部血流的突然阻塞而引起局部脑组织缺血坏死所导致的神经组织损伤。70％～80％有严重症状需要做动脉造影的病人可以见到栓子或血栓的阻塞。较大血管栓塞的致死率在53％～92％，研发出一中处理和清除急性缺血性脑卒中的血栓的取出装置成为一种日益增长的临床需求。完全处理和清除血栓从而使血管实现再通是治疗急性缺血性脑卒中的关键。目前的血栓取出技术能够至少部分恢复血管的通血能力，但是在恢复所有远端血管的通血能力上还存在很大的改进空间。更加致密、纤维化程度更高或更硬的血栓通常更加难以处理和清除，增加径向力可以增强血栓取出装置处理和清除血栓的能力。Acute ischemic stroke is caused by local brain tissue ischemia and necrosis due to sudden blockage of cerebral blood flow. 70% to 80% of patients with severe symptoms who need arterial angiography can see blockage of emboli or thrombus. The mortality rate of large vascular embolism is 53% to 92%. The development of a thrombus removal device for handling and removing thrombi in acute ischemic stroke has become an increasing clinical need. Completely handling and removing thrombi so that blood vessels can be recanalized is the key to treating acute ischemic stroke. Current thrombus removal technology can at least partially restore the blood flow capacity of blood vessels, but there is still much room for improvement in restoring the blood flow capacity of all distal blood vessels. More dense, more fibrotic or harder thrombi are usually more difficult to handle and remove. Increasing radial force can enhance the ability of thrombus removal devices to handle and remove thrombi.
依赖于自膨胀镍钛合金的取栓支架是血栓取出装置的重要组成部件，由于取栓支架自身的柔韧性和结构问题，其径向支撑强度会受到很大限制。当收回血栓取出装置的取栓支架以将血栓导入抽吸导管时，取栓支架近端的张力会导致取栓支架的主体段收到挤压并且直径减小，从而降低其处理和清除血栓的能力。The thrombectomy stent, which relies on self-expanding nickel-titanium alloy, is an important component of the thrombus retrieval device. Due to the flexibility and structural problems of the thrombectomy stent itself, its radial support strength is greatly limited. When the thrombectomy stent of the thrombus retrieval device is retracted to guide the thrombus into the aspiration catheter, the tension at the proximal end of the thrombectomy stent will cause the main section of the thrombectomy stent to be squeezed and the diameter to be reduced, thereby reducing its ability to handle and remove thrombi.
其他依赖于可调节径向支撑强度的取栓支架通常包括至少一具有推拉作用的牵引丝的编织结构。这种结构的取栓支架的缺点是其管径通常非常小，且当牵引丝处于拉紧状态时，编织结构会在压力最小的位置膨胀，而这些位置往往是没有血栓的地方。Other thrombectomy stents that rely on adjustable radial support strength usually include a braided structure of at least one traction wire with a push-pull effect. The disadvantage of this type of thrombectomy stent is that its diameter is usually very small, and when the traction wire is in a taut state, the braided structure will expand at the location with the least pressure, which is often where there is no thrombus.
需要说明的是，在上述背景技术部分公开的信息仅用于加强对本发明的背景的理解，因此可以包括不构成对本领域普通技术人员已知的现有技术的信息。It should be noted that the information disclosed in the above background technology section is only used to enhance the understanding of the background of the present invention, and therefore may include information that does not constitute the prior art known to ordinary technicians in the field.
发明内容Summary of the invention
针对现有技术中的问题，本发明的目的在于提供处理和清除血栓性能更佳的血栓取出装置，从而可以提高临床血运重建率并改善患者中风后的生活。In view of the problems in the prior art, the purpose of the present invention is to provide a thrombus removal device with better performance in handling and clearing thrombi, thereby increasing the clinical revascularization rate and improving the life of patients after stroke.
本发明实施例提供一种血栓取出装置，包括自膨胀的取栓支架、具有中空内腔的推送杆、牵引丝以及至少一支撑组件；The embodiment of the present invention provides a thrombus removal device, comprising a self-expanding thrombus removal stent, a push rod with a hollow inner cavity, a traction wire, and at least one support assembly;
所述取栓支架为相互连接的两根以上筋条组成的管状网格结构；The thrombus removal stent is a tubular grid structure composed of two or more ribs connected to each other;
所述取栓支架的近端与所述推送杆的远端固定连接；The proximal end of the thrombus removal bracket is fixedly connected to the distal end of the pushing rod;
所述牵引丝分别贯通所述推送杆和所述取栓支架，所述牵引丝的远端与所述取栓支架的远端连接，且所述牵引丝可在所述推送杆的中空内腔内滑动；The traction wire passes through the pushing rod and the thrombus removal stent respectively, the distal end of the traction wire is connected to the distal end of the thrombus removal stent, and the traction wire can slide in the hollow inner cavity of the pushing rod;
所述支撑组件的两端分别与所述牵引丝和所述取栓支架相连接。Two ends of the support assembly are respectively connected to the traction wire and the thrombus removal bracket.
根据本发明的一些示例，所述支撑组件包括连接支座和至少一支撑筋；According to some examples of the present invention, the support assembly includes a connecting support and at least one support rib;
所述连接支座与所述牵引丝相连接；The connecting support is connected to the traction wire;
所述支撑筋的第一端与所述连接支座相连接，所述支撑筋的第二端与所述取栓支架相连接。The first end of the support rib is connected to the connecting support, and the second end of the support rib is connected to the thrombus removal bracket.
根据本发明的一些示例，所述连接支座与所述牵引丝固定连接。According to some examples of the present invention, the connecting support is fixedly connected to the traction wire.
根据本发明的一些示例，所述血栓取出装置包括多个支撑组件；各个所述支撑组件的连接支座沿所述牵引丝周期性分布。According to some examples of the present invention, the thrombus removal device includes a plurality of support components; the connecting supports of each of the support components are periodically distributed along the traction wire.
根据本发明的一些示例，所述支撑组件还包括第一限位件；According to some examples of the present invention, the support assembly further includes a first stopper;
所述第一限位件设置于所述牵引丝上且位于所述连接支座的远端，且当所述牵引丝的远端向所述推送杆移动时，所述第一限位件带动所述连接支座向所述推送杆移动。The first limiting member is arranged on the traction wire and is located at the distal end of the connecting support, and when the distal end of the traction wire moves toward the pushing rod, the first limiting member drives the connecting support to move toward the pushing rod.
根据本发明的一些示例，所述支撑筋的第二端与所述取栓支架的筋条之间的交叉节点相连接。According to some examples of the present invention, the second end of the support rib is connected to a cross node between the ribs of the thrombus removal stent.
根据本发明的一些示例，所述支撑筋与所述取栓支架的筋条为一体成型件。According to some examples of the present invention, the support ribs and the ribs of the thrombus removal bracket are integrally formed.
根据本发明的一些示例，所述牵引丝还包括一第二限位件；According to some examples of the present invention, the traction wire further includes a second limiting member;
所述第二限位件的至少一处外轮廓的尺寸大于所述推送杆的中空内腔的直径；The size of at least one outer contour of the second stopper is larger than the diameter of the hollow inner cavity of the push rod;
所述第二限位件设置于所述牵引丝上靠近所述推送杆的一侧。The second limiting member is arranged on a side of the traction wire close to the pushing rod.
根据本发明的一些示例，所述第二限位件包括显影件。According to some examples of the present invention, the second limiting member includes a developing member.
根据本发明的一些示例，所述取栓支架的筋条、所述筋条之间的交叉节点，和/或，所述牵引丝的远端包括显影件。According to some examples of the present invention, the ribs of the thrombus removal stent, the cross nodes between the ribs, and/or the distal end of the traction wire include a developing member.
根据本发明的一些示例，所述取栓支架的筋条和/或所述筋条之间的交叉节点处设置贴合部；所述贴合部与所述取栓支架的筋条一体成型；所述显影件连接于所述贴合部。According to some examples of the present invention, a fitting portion is provided at the ribs of the thrombus retrieval bracket and/or at the intersection nodes between the ribs; the fitting portion is integrally formed with the ribs of the thrombus retrieval bracket; and the developing member is connected to the fitting portion.
根据本发明的一些示例，所述显影件采用铂铱合金、铂镍合金、铂钨合金、钨、钽、钨钽合金或金中的一种或多种的组合制备而成。According to some examples of the present invention, the developing member is made of a combination of one or more of platinum-iridium alloy, platinum-nickel alloy, platinum-tungsten alloy, tungsten, tantalum, tungsten-tantalum alloy or gold.
根据本发明的一些示例，所述取栓支架包括主体段、所述主体段与所述推送杆之间的过渡段以及位于所述主体段远端的支架远端，所述支架远端是封闭的。According to some examples of the present invention, the thrombus removal stent includes a main body section, a transition section between the main body section and the pushing rod, and a stent distal end located at the distal end of the main body section, and the stent distal end is closed.
根据本发明的一些示例，所述取栓支架采用不锈钢、钴铬合金、具有形状记忆效应的金属材料或高弹体聚合物制作而成；和/或According to some examples of the present invention, the thrombus removal stent is made of stainless steel, cobalt-chromium alloy, metal material with shape memory effect or elastomeric polymer; and/or
所述牵引丝为镍钛合金、不锈钢或高弹体聚合物制作而成。The traction wire is made of nickel-titanium alloy, stainless steel or high-elastic polymer.
根据本发明的一些示例，所述血栓取出装置至少满足如下一条件：According to some examples of the present invention, the thrombus removal device satisfies at least one of the following conditions:
所述取栓支架的筋条的宽度为0.02mm～0.2mm；The ribs of the thrombus removal bracket have a width of 0.02 mm to 0.2 mm;
所述取栓支架的筋条的厚度为0.02mm～0.2mm；The thickness of the ribs of the thrombus removal bracket is 0.02 mm to 0.2 mm;
所述支撑筋的宽度为0.02mm～0.2mm；The width of the support rib is 0.02 mm to 0.2 mm;
所述支撑筋的厚度为0.02mm～0.2mm。The thickness of the supporting rib is 0.02 mm to 0.2 mm.
本发明的血栓取出装置的取栓支架通过支撑组件增加了自膨胀取栓支架的径向支撑强度，使其即使在大的压力下也能保持一定的膨胀管径，增加取栓支架的血栓清除成功率，增强其处理和清除血管中血栓(尤其是致密度、纤维化程度、硬度更高的血栓)的能力，提高血栓取回装置处理和清除血栓性能，从而可以提高临床血运重建率并改善患者中风后的生活。The thrombus removal device of the present invention increases the radial support strength of the self-expanding thrombus removal device through the support component, so that it can maintain a certain expansion diameter even under high pressure, increase the thrombus removal success rate of the thrombus removal device, enhance its ability to handle and remove thrombi in blood vessels (especially thrombi with higher density, fibrosis and hardness), improve the thrombus handling and removal performance of the thrombus retrieval device, thereby improving the clinical revascularization rate and improving the patient's life after stroke.
附图说明BRIEF DESCRIPTION OF THE DRAWINGS
此处的附图被并入说明书中并构成本说明书的一部分，示出了符合本申请的实施例，并与说明书一起用于解释本申请的原理，通过阅读参照以下附图对非限制性实施例所作的详细描述，本发明的其它特征、目的和优点将会变得更明显。显而易见地，下面描述中的附图仅仅是本发明的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。The drawings herein are incorporated into the specification and constitute a part of the specification, showing embodiments consistent with the present application, and together with the specification, are used to explain the principles of the present application. By reading the detailed description of the non-limiting embodiments with reference to the following drawings, other features, purposes and advantages of the present invention will become more obvious. Obviously, the drawings in the following description are only some embodiments of the present invention, and for ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.
图1是本发明的第一实施例的血栓取出装置的结构示意图；FIG1 is a schematic structural diagram of a thrombus removal device according to a first embodiment of the present invention;
图2是本发明的第一实施例的取栓支架的平铺展开后的结构示意图；FIG2 is a schematic structural diagram of the thrombus removal stent after being spread out in a flat manner according to the first embodiment of the present invention;
图3是第一实施例的取栓支架的支架远端的结构示意图；FIG3 is a schematic structural diagram of the distal end of the thrombus removal stent of the first embodiment;
图4是本发明的一实施例的部分取栓支架的平铺展开后的结构示意图；FIG4 is a schematic structural diagram of a portion of the thrombus removal stent after being spread out in a flat manner according to an embodiment of the present invention;
图5是本发明的第二实施例的血栓取出装置的结构示意图；FIG5 is a schematic structural diagram of a thrombus removal device according to a second embodiment of the present invention;
图6～图7是本发明的一些实施例的部分取栓支架的平铺展开后的结构示意图。6 and 7 are schematic diagrams of the structure of a portion of the thrombectomy stent after being spread out in accordance with some embodiments of the present invention.
附图标记：Reference numerals:
10 取栓支架10 Thrombectomy Stent
11 过渡段11 Transition
12 主体段12 Main body
121 筋条121 tendons
122 网格122 Grid
123 交叉节点123 cross node
124 贴合部124 Lamination Department
13 支架远端13 Distal end of stent
20 推送杆20 Push rod
30 牵引丝30 Traction wire
31 第二限位件31 Second limiter
41 连接支座41 Connecting bracket
42 支撑筋42 Support ribs
421 第一端421 First End
422 第二端422 Second End
43 第一限位件43 First stopper
具体实施方式Detailed ways
现在将参考附图更全面地描述示例实施方式。然而，示例实施方式能够以多种形式实施，且本发明不应被理解为限于在此阐述的实施方式；相反，提供这些实施方式将使得本发明更全面和完整，并将示例实施方式的构思全面地传达给本领域的技术人员。在图中相同的附图标记表示相同或类似的结构，因而将省略对它们的重复描述。说明书中的的术语“或”和“和 /或”被解释为包括性的，或意味着任一个或任何组合。因此，“A、B或C”或者“A、B和/或C”意味着“以下任一个：A；B；C；A和B；A和C；B 和C；A、B和C”。仅当元件、功能、步骤或操作的组合在某些方式下内在地互相排斥时，才会出现该定义的例外。本发明中所指远端是相对于近端来说的，近端指的是靠近操作者的一端，远端指的是远离操作者的一端。The example embodiments will now be described more fully with reference to the accompanying drawings. However, the example embodiments can be implemented in a variety of forms, and the present invention should not be construed as limited to the embodiments set forth herein; on the contrary, providing these embodiments will make the present invention more comprehensive and complete, and will fully convey the concept of the example embodiments to those skilled in the art. The same reference numerals in the figures represent the same or similar structures, and thus their repeated description will be omitted. The terms "or" and "and/or" in the specification are interpreted as inclusive, or mean any one or any combination. Therefore, "A, B or C" or "A, B and/or C" means "any of the following: A; B; C; A and B; A and C; B and C; A, B and C". Exceptions to this definition will only occur when the combination of elements, functions, steps or operations is inherently mutually exclusive in some manner. The distal end referred to in the present invention is relative to the proximal end, and the proximal end refers to the end close to the operator, and the distal end refers to the end away from the operator.
在本发明的描述中，需要理解的是，术语“第一”、“第二”仅用于描述目的，而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量。由此，限定有“第一”、“第二”的特征可以明示或者隐含地包括一个或者更多个特征。在本发明的描述中，“多个”的含义是两个或两个以上，除非另有明确具体的限定。In the description of the present invention, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, features defined as "first" and "second" may explicitly or implicitly include one or more features. In the description of the present invention, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.
在通篇说明书中，当说某器件与另一器件“连接”时，这不仅包括“直接连接”的情形，也包括在其中间把其它元件置于其间而“间接连接”的情形。另外，当说某种器件“包括”某种构成要素时，只要没有特别相反的记载，则并非将其它构成要素排除在外，而是意味着可以还包括其它构成要素。Throughout the specification, when a device is said to be "connected" to another device, this includes not only the case of "direct connection" but also the case of "indirect connection" by placing other elements therebetween. In addition, when a device is said to "include" a certain component, unless otherwise stated, it does not exclude other components, but means that other components may be included.
下文的公开提供了许多不同的实施例或例子用来实现本发明的不同结构。为了简化本发明的公开，下文中对特定例子的部件和设定进行描述。当然，它们仅仅为示例，并且目的不在于限制本发明。此外，本发明可以在不同例子中重复参考数字和/或参考字母，这种重复是为了简化和清楚的目的，其本身不指示所讨论各种实施例和/或设定之间的关系。此外，本发明提供了的各种特定的工艺和材料的例子，但是本领域普通技术人员可以意识到其他工艺的应用和/或其他材料的使用。The disclosure below provides many different embodiments or examples to implement different structures of the present invention. In order to simplify the disclosure of the present invention, the components and settings of specific examples are described below. Of course, they are only examples, and the purpose is not to limit the present invention. In addition, the present invention can repeat reference numbers and/or reference letters in different examples, and this repetition is for the purpose of simplicity and clarity, which itself does not indicate the relationship between the various embodiments and/or settings discussed. In addition, the present invention provides various specific examples of processes and materials, but those of ordinary skill in the art can be aware of the application of other processes and/or the use of other materials.
本发明提供了一种血栓取出装置，包括自膨胀的取栓支架、具有中空内腔的推送杆、牵引丝以及至少一支撑组件；所述取栓支架为相互连接的两根以上筋条组成的管状网格结构；所述取栓支架的近端与所述推送杆的远端固定连接；所述牵引丝分别贯通所述推送杆和所述取栓支架，所述牵引丝的远端与所述取栓支架的远端连接，且所述牵引丝可在所述推送杆的中空内腔内滑动；所述支撑组件的两端分别与所述牵引丝和所述取栓支架相连接。本发明的血栓取出装置的取栓支架通过支撑组件增加了自膨胀取栓支架的径向支撑强度，使其即使在大的压力下也能保持一定的膨胀管径，从而增强其处理和清除血管中血栓(尤其是致密度、纤维化程度、硬度更高的血栓)的能力，提高血栓取回装置处理和清除血栓性能，从而可以提高临床血运重建率并改善患者中风后的生活。需要说的是，此处近端和远端是相对于操作者来说的，距离操作者较近的一端为近端，距离操作者较远的一端为远端。The present invention provides a thrombus removal device, comprising a self-expanding thrombus removal stent, a push rod with a hollow inner cavity, a traction wire and at least one support assembly; the thrombus removal stent is a tubular grid structure composed of two or more ribs connected to each other; the proximal end of the thrombus removal stent is fixedly connected to the distal end of the push rod; the traction wire passes through the push rod and the thrombus removal stent respectively, the distal end of the traction wire is connected to the distal end of the thrombus removal stent, and the traction wire can slide in the hollow inner cavity of the push rod; the two ends of the support assembly are respectively connected to the traction wire and the thrombus removal stent. The thrombus removal stent of the thrombus removal device of the present invention increases the radial support strength of the self-expanding thrombus removal stent through the support assembly, so that it can maintain a certain expansion tube diameter even under high pressure, thereby enhancing its ability to handle and remove thrombi in blood vessels (especially thrombi with higher density, fibrosis and hardness), and improving the thrombus handling and removal performance of the thrombus retrieval device, thereby improving the clinical revascularization rate and improving the life of patients after stroke. It should be noted that the proximal end and the distal end here are relative to the operator. The end closer to the operator is the proximal end, and the end farther from the operator is the distal end.
下面结合附图详细介绍本发明各个具体实施例的血栓取出装置的结构，可以理解的是，各个具体实施例不作为本发明的保护范围的限制。The structures of the thrombus removal devices of various specific embodiments of the present invention are described in detail below with reference to the accompanying drawings. It should be understood that the various specific embodiments are not intended to limit the protection scope of the present invention.
图1是本发明的第一实施例的血栓取出装置的结构示意图，该血栓取出装置包括自膨胀的取栓支架10、具有中空内腔的推送杆20、牵引丝30 以及至少一支撑组件；FIG1 is a schematic structural diagram of a thrombus removal device according to a first embodiment of the present invention, wherein the thrombus removal device comprises a self-expanding thrombus removal stent 10, a push rod 20 having a hollow inner cavity, a traction wire 30, and at least one supporting assembly;
所述取栓支架10为相互连接的两根以上筋条121组成的管状网格结构；The thrombus removal stent 10 is a tubular grid structure composed of two or more ribs 121 connected to each other;
所述取栓支架10的近端与所述推送杆20的远端固定连接；The proximal end of the thrombus removal bracket 10 is fixedly connected to the distal end of the pushing rod 20;
所述牵引丝30分别贯通所述推送杆20和所述取栓支架10，所述牵引丝30的远端与所述取栓支架10的远端连接，且所述牵引丝30可在所述推送杆20的中空内腔内滑动。所述牵引丝30可以为镍钛合金、不锈钢或高弹体聚合物制作而成。且所述支撑组件的两端分别与所述牵引丝30 和所述取栓支架10相连接。The traction wire 30 passes through the push rod 20 and the thrombus removal stent 10 respectively, and the distal end of the traction wire 30 is connected to the distal end of the thrombus removal stent 10, and the traction wire 30 can slide in the hollow inner cavity of the push rod 20. The traction wire 30 can be made of nickel-titanium alloy, stainless steel or elastomeric polymer. The two ends of the support component are connected to the traction wire 30 and the thrombus removal stent 10 respectively.
根据取栓支架的结构，进一步的，可以将所述取栓支架10分为三个部分，即主体段12、所述主体段12与推送杆20之间的过渡段11以及位于取栓支架10远端的支架远端13，且所述支架远端是封闭的。取栓支架 10的过渡段11具有自主体段12至推送杆20的远端的渐缩结构，且该渐缩结构形成一锥形，主体段12呈圆柱形的管状，支架远端13自主体段 12至牵引丝30的远端至也呈渐缩结构，且该渐缩结构形成一锥形。取栓支架10的尺寸，尤其是管状主体段12膨胀态时的直径等可以根据目标血管的尺寸设定。According to the structure of the thrombus retrieval stent, the thrombus retrieval stent 10 can be further divided into three parts, namely, the main body section 12, the transition section 11 between the main body section 12 and the push rod 20, and the stent distal end 13 located at the distal end of the thrombus retrieval stent 10, and the stent distal end is closed. The transition section 11 of the thrombus retrieval stent 10 has a tapered structure from the main body section 12 to the distal end of the push rod 20, and the tapered structure forms a cone. The main body section 12 is a cylindrical tube, and the stent distal end 13 also has a tapered structure from the main body section 12 to the distal end of the traction wire 30, and the tapered structure forms a cone. The size of the thrombus retrieval stent 10, especially the diameter of the tubular main body section 12 in the expanded state, can be set according to the size of the target blood vessel.
所述取栓支架10可以采用不锈钢、钴铬合金、具有形状记忆效应的金属材料或高弹体聚合物制作而成，如采用具有形状记忆效应的镍钛合金、不锈钢或钴铬合金等。所述取栓支架10为相互连接的两根以上筋条121 组成的管状网格结构。图2是本发明的第一实施例的取栓支架的平铺展开后的结构示意图，以主体段12的网状结构为例，多根筋条121连接组成多个网格122，两个筋条121之间的连接点定义为交叉节点123，网状结构除了形成自膨胀的结构外，另一个作用在于使血栓吸附在多根筋条121 上，能够更好的俘获血栓，从而更彻底地清除血管中的血栓。管状的主体段12各处的直径可以一致的，也可以是不一致的，如图1所示，如膨胀态的主体段12的直径沿牵引丝方向呈周期性的变化。The thrombus removal stent 10 can be made of stainless steel, cobalt-chromium alloy, metal material with shape memory effect or elastomeric polymer, such as nickel-titanium alloy, stainless steel or cobalt-chromium alloy with shape memory effect. The thrombus removal stent 10 is a tubular mesh structure composed of two or more ribs 121 connected to each other. FIG2 is a schematic diagram of the structure of the thrombus removal stent after flattening and unfolding in the first embodiment of the present invention. Taking the mesh structure of the main body section 12 as an example, multiple ribs 121 are connected to form multiple meshes 122, and the connection point between two ribs 121 is defined as a cross node 123. In addition to forming a self-expanding structure, the mesh structure also has another function of allowing thrombi to be adsorbed on multiple ribs 121, which can better capture thrombi and thus more thoroughly remove thrombi in blood vessels. The diameters of the tubular main body section 12 can be consistent or inconsistent at various locations. As shown in FIG1, the diameter of the expanded main body section 12 changes periodically along the direction of the traction wire.
上述网状结构可以通过激光切割具有高弹性的金属管获得，激光切割的优点是不存在多根筋条之间的焊点结构，从而不易发生移位现象，结构强度大；同时，可以采用电抛光等方法以确保筋条表面和边缘的平滑，从而与血管形成无损伤的相互作用。此外，激光切割的优点还在于可以设计激光切割图案从而获得一定结构的取栓支架，如主体段膨胀态时的直径、网格的大小等均可以通过设计激光切割图案确定。优选地，取栓支架采用的镍钛合金材料为镍钛，镍钛在受压时会表现出超弹性。采用有高弹性材料制成的取栓支架具有自膨胀性，即具有收缩态和膨胀态两种状态，取栓支架在工作时，能够在收缩态与膨胀态之间变换。The above-mentioned mesh structure can be obtained by laser cutting a metal tube with high elasticity. The advantage of laser cutting is that there is no welding point structure between multiple ribs, so it is not easy to shift and the structural strength is large; at the same time, methods such as electropolishing can be used to ensure the smoothness of the rib surface and edges, so as to form a non-destructive interaction with the blood vessels. In addition, the advantage of laser cutting is that the laser cutting pattern can be designed to obtain a thrombectomy stent with a certain structure. For example, the diameter of the main section in the expanded state, the size of the grid, etc. can be determined by designing the laser cutting pattern. Preferably, the nickel-titanium alloy material used in the thrombectomy stent is nickel-titanium, which exhibits superelasticity when under pressure. The thrombectomy stent made of highly elastic material is self-expandable, that is, it has two states: a contracted state and an expanded state. The thrombectomy stent can switch between the contracted state and the expanded state when it is working.
第一实施例中，支架远端13也为网状结构，取栓支架10的支架远端 13的网状结构与所述牵引丝30的远端形成连接，且该处的连接形成封闭结构，连接后的结构可以如图3所示。取栓支架10的支架远端13的网状结构的筋条可以通过粘接、焊接或熔接等方式与牵引丝30的远端相连接，此处的连接可以看成是活动性连接，即与牵引丝30的远端连接的筋条121 与牵引线之间的夹角随着取栓支架的收缩态与膨胀态之间的变换而变化。In the first embodiment, the distal end 13 of the stent is also a mesh structure, and the mesh structure of the distal end 13 of the stent of the thrombectomy stent 10 is connected to the distal end of the traction wire 30, and the connection here forms a closed structure, and the structure after connection can be shown in Figure 3. The ribs of the mesh structure of the distal end 13 of the stent of the thrombectomy stent 10 can be connected to the distal end of the traction wire 30 by bonding, welding or fusion, and the connection here can be regarded as an active connection, that is, the angle between the ribs 121 connected to the distal end of the traction wire 30 and the traction wire changes with the transformation between the contraction state and the expansion state of the thrombectomy stent.
取栓支架10的过渡段11自主体段12至推送杆20的远端呈渐缩结构的锥角小于支架远端13自主体段12至牵引丝30的远端渐缩结构的锥角。可以合理设计过渡段11的锥角，从而提高取栓支架捕获血栓后退出血管的通过性和输送性。支架远端13的网状结构与主体段12的网状结构不同，支架远端13自主体段12至牵引丝30的远端至渐缩的锥形结构使得所述支架远端13的网格尺寸小于所述主体段12的网格尺寸，即支架远端13 的筋条的密度大于主体段12的筋条的密度，封闭且更密的网状结构的支架远端结构可以使血栓取出装置在捕获血栓后从血管退出的过程中确保血栓不会从支架远端漏出，使血栓尽可能地容纳在取栓支架之内，以尽量减少血管中血栓残渣的留存。The taper angle of the transition section 11 of the thrombus removal stent 10 from the main section 12 to the distal end of the push rod 20 is smaller than the taper angle of the distal end 13 of the stent from the main section 12 to the distal end of the traction wire 30. The taper angle of the transition section 11 can be reasonably designed to improve the passability and transportability of the thrombus removal stent after capturing the thrombus and withdrawing from the blood vessel. The mesh structure of the stent distal end 13 is different from the mesh structure of the main section 12. The tapered structure of the stent distal end 13 from the main section 12 to the distal end of the traction wire 30 makes the mesh size of the stent distal end 13 smaller than the mesh size of the main section 12, that is, the density of the ribs of the stent distal end 13 is greater than the density of the ribs of the main section 12. The closed and denser mesh structure of the stent distal end structure can ensure that the thrombus will not leak from the stent distal end during the process of the thrombus removal device withdrawing from the blood vessel after capturing the thrombus, so that the thrombus is contained in the thrombus removal stent as much as possible to minimize the retention of thrombus residues in the blood vessel.
第一实施例中，所述支撑组件可以包括连接支座41和至少一与所述连接支座41连接的支撑筋42；此时，支撑组件的一端为连接支座41，另一端即为支撑筋42不与连接支座41相连接的一端。In the first embodiment, the support assembly may include a connecting support 41 and at least one supporting rib 42 connected to the connecting support 41; in this case, one end of the support assembly is the connecting support 41, and the other end is the end of the supporting rib 42 that is not connected to the connecting support 41.
具体的，所述连接支座41与所述牵引丝30相连接；所述支撑筋42 的第一端421与所述连接支座41相连接，所述支撑筋42的第二端422与所述取栓支架10相连接。支撑筋42的第二端422可以与取栓支架10的筋条121相连接，优选地，支撑筋42的第二端422可以与所述取栓支架的筋条121之间的交叉节点123相连接，第二端422与交叉节点123连接时的支撑强度高于第二端422与单根筋条121连接的支撑强度。Specifically, the connection support 41 is connected to the traction wire 30; the first end 421 of the support rib 42 is connected to the connection support 41, and the second end 422 of the support rib 42 is connected to the thrombus removal bracket 10. The second end 422 of the support rib 42 can be connected to the rib 121 of the thrombus removal bracket 10. Preferably, the second end 422 of the support rib 42 can be connected to the cross node 123 between the ribs 121 of the thrombus removal bracket, and the support strength when the second end 422 is connected to the cross node 123 is higher than the support strength when the second end 422 is connected to a single rib 121.
此实施例中，所述连接支座41与所述牵引丝30之间的连接可以是固定连接，当拉动牵引丝30沿推送杆20的中空内腔向近端方向(图1中虚线箭头方向)滑动时，支撑筋42与牵引丝30之间的夹角变大，多根支撑筋42支撑与之连接的取栓支架10的筋条121或筋条121之间的交叉节点 123，从而使取栓支架10的直径增大。取栓支架10的主体段12的直径根据目标血管的直径设置，通常略大于目标血管的直径，相应地，支撑筋的长度应至少大于主体段12的半径，从而使其展开时能过支撑取栓支架。In this embodiment, the connection between the connecting support 41 and the traction wire 30 can be a fixed connection. When the traction wire 30 is pulled to slide along the hollow inner cavity of the push rod 20 toward the proximal direction (the direction of the dotted arrow in FIG. 1 ), the angle between the support rib 42 and the traction wire 30 becomes larger, and multiple support ribs 42 support the ribs 121 of the thrombectomy stent 10 connected thereto or the cross nodes 123 between the ribs 121, thereby increasing the diameter of the thrombectomy stent 10. The diameter of the main body section 12 of the thrombectomy stent 10 is set according to the diameter of the target blood vessel, and is usually slightly larger than the diameter of the target blood vessel. Accordingly, the length of the support ribs should be at least larger than the radius of the main body section 12, so that it can support the thrombectomy stent when it is deployed.
支撑筋的数量可以根据取栓支架10中具体的网格结构设置，通常，可以与连接支座处的取栓支架10周向的交叉节点的数量相当，优选地，管状的取栓支架10的交叉节点在周向上是均匀分布的，如第一实施例中，在管状的取栓支架10的周向上均匀分布的交叉节点的数量为3，此时，支撑组件可以设置三根支撑筋42。The number of support ribs can be set according to the specific grid structure in the thrombectomy bracket 10. Generally, it can be equivalent to the number of circumferential cross nodes of the thrombectomy bracket 10 at the connection support. Preferably, the cross nodes of the tubular thrombectomy bracket 10 are evenly distributed in the circumferential direction. For example, in the first embodiment, the number of cross nodes evenly distributed in the circumferential direction of the tubular thrombectomy bracket 10 is 3. In this case, the support assembly can be provided with three support ribs 42.
上述实施例中的支撑组件的连接支座41与牵引丝30、连接支座41 与支撑筋42，或者是支撑筋42与取栓支架10之间均可以通过粘接、焊接或熔接等方式实现连接，本发明不限定其他的连接方式，在其他可替代的实施方式中，也可以采用此处列举之外的连接方式。The connection between the connecting support 41 and the traction wire 30, the connecting support 41 and the supporting rib 42, or the supporting rib 42 and the thrombus removal bracket 10 of the support assembly in the above-mentioned embodiment can be achieved by bonding, welding or melting. The present invention does not limit other connection methods. In other alternative embodiments, connection methods other than those listed here can also be used.
在多根支撑筋42与多个筋条之间的交叉节点123连接的实施例中，如第一实施例，多个支撑筋与取栓支架的筋条可以是一体化设计成型的一体件，如在使用激光切割具有高弹性的金属管的同时，通过设计激光切割图案使其包括取栓支架的筋条121和与交叉节点123连接的支撑筋42，激光切割后包括有支撑筋42的取栓支架的平铺展开后的结构示意图可以如图4所示。此时，再将支撑筋42的第一端与牵引丝30上的连接支座 41连接实现第一实施例支撑组件的结构。多个支撑筋与取栓支架的筋条为一体成型件可以避免另外的焊接等工序，同时，可以保证支撑筋与取栓支架之间的连接强度，不易发生移位现象，从而提高支撑筋径向的支撑强度。In the embodiment where multiple support ribs 42 are connected to the cross nodes 123 between multiple ribs, as in the first embodiment, multiple support ribs and the ribs of the thrombectomy stent can be an integrated piece designed and formed in an integrated manner. For example, when using laser cutting of a metal tube with high elasticity, the laser cutting pattern is designed to include the ribs 121 of the thrombectomy stent and the support ribs 42 connected to the cross nodes 123. The structural schematic diagram of the thrombectomy stent after flattening and unfolding including the support ribs 42 after laser cutting can be shown in FIG. 4. At this time, the first end of the support rib 42 is connected to the connecting support 41 on the traction wire 30 to realize the structure of the support assembly of the first embodiment. Multiple support ribs and the ribs of the thrombectomy stent are an integrated piece, which can avoid additional welding and other processes. At the same time, the connection strength between the support ribs and the thrombectomy stent can be guaranteed, and displacement is not easy to occur, thereby improving the radial support strength of the support ribs.
图5是本发明的第二实施例的血栓取出装置的结构示意图，其中，支撑组件包括连接支座41、多根与连接支座41连接的支撑筋42以及一设置于所述牵引丝30的第一限位件43，与第一实施例不同的是，第二实施例的所述连接支座41与所述牵引丝30滑动连接，如连接支座41可以为一套设于牵引丝30的圆环结构，第一限位件43设置于所述牵引丝30上且位于所述连接支座41的远端，当拉动牵引丝30沿推送杆20的中空内腔向近端方向(图中虚线箭头方向)滑动时，第一限位件43向推送杆移动，当与连接支座41抵触时，带动连接支座41向推送杆移动，此时，支撑筋42与牵引丝30之间的夹角变大，多根支撑筋42支撑与之连接的取栓支架10的筋条121或筋条之间的交叉节点123，从而使取栓支架10的直径增大。第一限位件43的位置可以通过如下标准确定，第一限位件43 向推送杆20移动并与连接支座41抵触时，处于膨胀态的取栓支架的支撑筋42与牵引丝30之间的夹角小于90度。5 is a schematic structural diagram of a thrombus removal device according to a second embodiment of the present invention, wherein the support assembly comprises a connecting support 41, a plurality of supporting ribs 42 connected to the connecting support 41, and a first stopper 43 arranged on the traction wire 30. Different from the first embodiment, the connecting support 41 of the second embodiment is slidably connected to the traction wire 30. For example, the connecting support 41 may be a circular ring structure arranged on the traction wire 30. The first stopper 43 is arranged on the traction wire 30 and is located at the distal end of the connecting support 41. When the traction wire 30 is pulled to slide along the hollow inner cavity of the push rod 20 toward the proximal direction (the direction of the dotted arrow in the figure), the first stopper 43 moves toward the push rod. When it conflicts with the connecting support 41, it drives the connecting support 41 to move toward the push rod. At this time, the angle between the supporting rib 42 and the traction wire 30 becomes larger, and the plurality of supporting ribs 42 support the ribs 121 of the thrombus removal bracket 10 connected thereto or the cross nodes 123 between the ribs, thereby increasing the diameter of the thrombus removal bracket 10. The position of the first stopper 43 can be determined by the following standard: when the first stopper 43 moves toward the pushing rod 20 and contacts the connecting support 41 , the angle between the support rib 42 of the expanded thrombus removal stent and the traction wire 30 is less than 90 degrees.
在其他一些可替代的实施例中，血栓取出装置可以包括多个支撑组件，多个支撑组件的一端，即多个支撑组件的支撑底座可以沿牵引丝的延伸方向分布。多个支撑组件的支撑底座沿牵引丝的延伸方向分布可以是周期性的，如采用第一实施例中的支撑组件结构，则每间隔一段距离，牵引丝上设置一连接支座，在多个位置上与连接支座连接的多个支撑筋径向支撑取栓支架的管状主体段，从而提高整个取栓支架在径向上的强度。此处，多个支撑组件的支撑底座沿牵引丝的延伸方向的周期性分布可以是均匀分布，即相邻支撑底座之间的距离均相等，也可以是非均匀的，即相邻支撑底座之间不等距。支撑组件的结构不限于第一实施例和第二实施例所述的结构。多个支撑组件在牵引丝上的位置也可以根据取栓支架的结构以及血栓取出装置实际使用的场景合理设置，使其能更有针对性的增强取栓支架特定位置的径向强度。In some other alternative embodiments, the thrombus removal device may include multiple support components, and one end of the multiple support components, that is, the support bases of the multiple support components may be distributed along the extension direction of the traction wire. The distribution of the support bases of the multiple support components along the extension direction of the traction wire may be periodic. For example, if the support component structure in the first embodiment is adopted, a connecting support is provided on the traction wire at every interval, and multiple support ribs connected to the connecting support at multiple positions radially support the tubular main body section of the thrombus removal stent, thereby improving the radial strength of the entire thrombus removal stent. Here, the periodic distribution of the support bases of the multiple support components along the extension direction of the traction wire may be uniform, that is, the distances between adjacent support bases are equal, or may be non-uniform, that is, the distances between adjacent support bases are not equal. The structure of the support component is not limited to the structure described in the first embodiment and the second embodiment. The positions of the multiple support components on the traction wire may also be reasonably set according to the structure of the thrombus removal stent and the actual use scenario of the thrombus removal device, so that it can more specifically enhance the radial strength of the specific position of the thrombus removal stent.
如第二实施例中，支撑组件设置于主体段的中间部分，当取栓支架处于血栓处时，拉动牵引丝向近端移动时，支撑筋的径向力会施加到血栓上，而不是聚焦在取栓支架的末端，可以实现更佳的捕获血栓的效果。在另外一些实施例中，多个支撑组件中的几个与主体段12的交叉节点123连接，其他则和的筋条121相连接。本发明的血栓取出装置的取栓支架在径向上除了高弹性的筋条自身的支撑力外，增加了支撑组件的支撑力，可以潜在地增加取栓支架的血栓清除成功率。As in the second embodiment, the support assembly is disposed in the middle portion of the main body segment. When the thrombus removal stent is located at the thrombus, when the traction wire is pulled toward the proximal end, the radial force of the support ribs will be applied to the thrombus instead of focusing on the end of the thrombus removal stent, thereby achieving a better effect of capturing the thrombus. In other embodiments, several of the multiple support assemblies are connected to the intersection node 123 of the main body segment 12, and the others are connected to the ribs 121. In addition to the support force of the highly elastic ribs themselves in the radial direction, the thrombus removal stent of the thrombus removal device of the present invention increases the support force of the support assembly, which can potentially increase the success rate of thrombus removal of the thrombus removal stent.
在一些实施例中，所述牵引丝30还包括一第二限位件31；所述第二限位件131设置于所述牵引丝30上靠近所述推送杆20的一侧。，第二限位件31不能穿过推送杆20的中空内腔，则所述第二限位件31的至少一处外轮廓的尺寸大于所述推送杆20的中空内腔的直径。例如，当推送杆 20的中空内腔和第二限位件31的外径均为圆形时，第二限位件31的外径大于推送杆20的中空内腔的直径。In some embodiments, the traction wire 30 further includes a second stopper 31; the second stopper 31 is disposed on a side of the traction wire 30 close to the push rod 20. If the second stopper 31 cannot pass through the hollow inner cavity of the push rod 20, the size of at least one outer contour of the second stopper 31 is larger than the diameter of the hollow inner cavity of the push rod 20. For example, when the outer diameters of the hollow inner cavity of the push rod 20 and the second stopper 31 are both circular, the outer diameter of the second stopper 31 is larger than the diameter of the hollow inner cavity of the push rod 20.
在上述实施例中，牵引丝30向近端移动的过程可以看成是取栓支架从收缩态向膨胀态变化的过程，在取栓支架处于收缩态时，第二限位件 31与推送杆20的远端保持一阈值距离，当所述牵引丝30的远端向所述推送杆20移动一阈值距离后，所述第二限位件与推送杆的远端相抵触。上述阈值距离可以通过如下标准确定，当所述牵引丝30的远端向所述推送杆20移动一阈值距离后，处于膨胀态的取栓支架的支撑筋42与牵引丝 30之间的夹角小于90度，即牵引丝30向近端移动的距离要小于支撑筋 42的有效行程。In the above embodiment, the process of the traction wire 30 moving toward the proximal end can be regarded as the process of the thrombectomy stent changing from the contracted state to the expanded state. When the thrombectomy stent is in the contracted state, the second stopper 31 maintains a threshold distance with the distal end of the push rod 20. When the distal end of the traction wire 30 moves toward the push rod 20 by a threshold distance, the second stopper conflicts with the distal end of the push rod. The above threshold distance can be determined by the following standard: when the distal end of the traction wire 30 moves toward the push rod 20 by a threshold distance, the angle between the support rib 42 of the thrombectomy stent in the expanded state and the traction wire 30 is less than 90 degrees, that is, the distance that the traction wire 30 moves toward the proximal end is less than the effective stroke of the support rib 42.
需要说明的是，当所述连接支座41与所述牵引丝30之间的连接不是如第一实施例中固定连接，而是具有第二实施例中的结构时，要使牵引丝30向推送杆20方向能够移动的距离大于取栓支架处于收缩态时第一限位件43与连接支座41之间的距离，即当取栓支架处于收缩态时，所述第二限位件31与推送杆20的远端的距离需大于等于第一限位件43与连接支座41之间的距离，此时，牵引丝30向推送杆20方向移动的过程中，第一限位件43才能与连接支座41抵触带动连接支座移动，使得支撑筋42 与牵引丝30之间的夹角变大从而使取栓支架处于膨胀态。同时，所述第二限位件31与推送杆20的远端相抵触时处于膨胀态的取栓支架的支撑筋 42与牵引丝30之间的夹角小于90度。优选地，当取栓支架处于收缩态时，第一限位件43与连接支座41之间的距离等于第二限位件31与推送杆20的远端的距离。It should be noted that when the connection between the connecting support 41 and the traction wire 30 is not a fixed connection as in the first embodiment, but has a structure in the second embodiment, the distance that the traction wire 30 can move toward the push rod 20 is greater than the distance between the first stopper 43 and the connecting support 41 when the thrombus removal stent is in the contracted state, that is, when the thrombus removal stent is in the contracted state, the distance between the second stopper 31 and the distal end of the push rod 20 must be greater than or equal to the distance between the first stopper 43 and the connecting support 41. At this time, during the movement of the traction wire 30 toward the push rod 20, the first stopper 43 can contact the connecting support 41 to drive the connecting support to move, so that the angle between the support rib 42 and the traction wire 30 becomes larger, so that the thrombus removal stent is in the expanded state. At the same time, when the second stopper 31 contacts the distal end of the push rod 20, the angle between the support rib 42 of the thrombus removal stent in the expanded state and the traction wire 30 is less than 90 degrees. Preferably, when the thrombus removal stent is in the retracted state, the distance between the first limiting member 43 and the connecting support 41 is equal to the distance between the second limiting member 31 and the distal end of the pushing rod 20 .
第二限位件31的作用在于当拉动牵引丝30将整个取栓支架从血管收回时，限制牵引丝移动的范围，使取栓支架仍处于膨胀态且支撑筋有效地支撑取栓支架，从而使取栓支架更有效地带动捕获的血栓在血管内移动并退出血管，减少血栓在血管中的残留。The function of the second limiter 31 is to limit the range of movement of the traction wire 30 when the traction wire is pulled to retract the entire thrombus removal stent from the blood vessel, so that the thrombus removal stent is still in an expanded state and the supporting ribs effectively support the thrombus removal stent, so that the thrombus removal stent can more effectively drive the captured thrombus to move in the blood vessel and exit the blood vessel, reducing the residual thrombus in the blood vessel.
在实际的血栓取出装置的使用中，需要对取栓支架进行定位，使医生更便利地观察取栓支架的位置。在一些实施例中，所述取栓支架10的筋条121、所述筋条之间的交叉节点123，和/或，所述牵引丝30的远端可以包括显影件，此处的显影件是指在X射线检查下可见的部件，其构成材料具有不透射X射线的性能。In actual use of the thrombus removal device, the thrombus removal stent needs to be positioned so that the doctor can more conveniently observe the position of the thrombus removal stent. In some embodiments, the ribs 121 of the thrombus removal stent 10, the cross nodes 123 between the ribs, and/or the distal end of the traction wire 30 may include a developing member, where the developing member refers to a component visible under X-ray examination, and the material of which has the property of not transmitting X-rays.
显影件可以采用金属材料制备而成，优选地，可以采用具有较好的显影效果的铂铱合金、铂镍合金、铂钨合金、钨、钽、钨钽合金或金等金属材料中的一种或多种的组合，但本发明显影件不限于采用此处列举的金属材料，在其他可替代的实施方式中，也可以采用此处列举之外的金属材料。The developing part can be made of metal materials. Preferably, a combination of one or more metal materials with good developing effects such as platinum-iridium alloy, platinum-nickel alloy, platinum-tungsten alloy, tungsten, tantalum, tungsten-tantalum alloy or gold can be used. However, the developing part of the present invention is not limited to the metal materials listed here. In other alternative embodiments, metal materials other than those listed here may also be used.
所述取栓支架10的筋条121和/或筋条之间的交叉节点123包括显影件时，显影件可以通过粘接、焊接或熔接等方式直接连接于如第一实施例中的交叉节点123处和/或筋条121上。When the ribs 121 and/or the intersection nodes 123 between the ribs of the thrombus removal stent 10 include a developing member, the developing member can be directly connected to the intersection nodes 123 and/or the ribs 121 in the first embodiment by bonding, welding or fusing.
在其他一些实施例中，可以在筋条121和或筋条之间的交叉节点123 处另外设置显影件可以贴附的部分，如图6～图7所示的实施例，其为本发明的一些实施例的部分取栓支架的平铺展开后的结构示意图。图6实施例中，如采用激光切割方法制作取栓支架时，通过激光切割图案的设计，在取栓支架10的交叉节点123处增设条状或点状的贴合部124，以便可以通过后续的工艺将显影件附加在该条状或点状的贴合部124上。同样地，图7实施例中，如采用激光切割方法制作取栓支架时，通过激光切割图案的设计，在取栓支架10的筋条121处增设条状或点状的贴合部124，以便可以通过后续的工艺将显影件附加在该条状或点状的贴合部124上。显影件的位置及数量，即在取栓支架10上增设条状或点状的部件的位置及数量可以根据实际的使用场景设定。本发明对显影件的结构也不做限定，可以是如图6和图7中的条状，也可以是点状、环状等。在其他可替代的实施方式中，也可以采用此处列举之外的形状。显影件可以通过粘接、焊接或熔接等方式连接于交叉节点123处或筋条121上。设置于取栓支架的交叉节点或筋条上的显影件在X射线检查下可见，便于医生更好地监测取栓支架的状态。In some other embodiments, a portion to which a developer can be attached can be additionally provided at the ribs 121 and/or at the intersection nodes 123 between the ribs, as shown in the embodiments of FIGS. 6 and 7, which are schematic diagrams of the structure of a portion of the thrombectomy stent after being flattened and unfolded according to some embodiments of the present invention. In the embodiment of FIG. 6, when the thrombectomy stent is manufactured by a laser cutting method, a strip-shaped or dot-shaped affixed portion 124 is added at the intersection node 123 of the thrombectomy stent 10 by designing a laser cutting pattern, so that the developer can be attached to the strip-shaped or dot-shaped affixed portion 124 through a subsequent process. Similarly, in the embodiment of FIG. 7, when the thrombectomy stent is manufactured by a laser cutting method, a strip-shaped or dot-shaped affixed portion 124 is added at the ribs 121 of the thrombectomy stent 10 by designing a laser cutting pattern, so that the developer can be attached to the strip-shaped or dot-shaped affixed portion 124 through a subsequent process. The position and number of the developer, that is, the position and number of the strip-shaped or dot-shaped components added to the thrombectomy stent 10 can be set according to the actual use scenario. The present invention does not limit the structure of the developing member, which may be a strip as shown in FIG. 6 and FIG. 7 , or a dot, ring, etc. In other alternative embodiments, shapes other than those listed here may also be used. The developing member may be connected to the intersection node 123 or the rib 121 by bonding, welding, or welding. The developing member disposed on the intersection node or rib of the thrombectomy stent is visible under X-ray examination, which facilitates the doctor to better monitor the status of the thrombectomy stent.
相同地，所述牵引丝30的远端，和或，第二限位件31也可以包括具有不透射X射线的显影件，如可以在牵引丝30的远端与取栓支架10的远端的连接处设置环形的显影件，环状的显影件套设于牵引丝的远端。显影件的结构以及其与远端的连接方式在此也不做限制。牵引丝30的远端和第二限位件31包括具有不透射X射线的显影件可以便利于医生观察整个取栓过程中牵引丝的位置。Similarly, the distal end of the traction wire 30 and/or the second stopper 31 may also include a developing member that does not transmit X-rays, such as an annular developing member may be provided at the connection between the distal end of the traction wire 30 and the distal end of the thrombus removal bracket 10, and the annular developing member may be sleeved on the distal end of the traction wire. The structure of the developing member and the connection method with the distal end are not limited here. The distal end of the traction wire 30 and the second stopper 31 including the developing member that does not transmit X-rays can facilitate the doctor to observe the position of the traction wire during the entire thrombus removal process.
需要说明的是，本发明的取栓支架的筋条的尺寸可以根据取栓支架的整体强度的需要设定，筋条的横截面可以是圆形的、椭圆形的或者是长方形等。取栓支架的筋条的横截面优选为长方形，取栓支架的筋条的宽度可选为0.02mm～0.2mm，优选为0.05mm～0.08mm，所述取栓支架的筋条的厚度可选为0.02mm～0.2mm。优选为0.05mm～0.08mm。It should be noted that the size of the ribs of the thrombectomy stent of the present invention can be set according to the overall strength requirements of the thrombectomy stent, and the cross-section of the ribs can be circular, elliptical or rectangular. The cross-section of the ribs of the thrombectomy stent is preferably rectangular, the width of the ribs of the thrombectomy stent can be selected from 0.02mm to 0.2mm, preferably 0.05mm to 0.08mm, and the thickness of the ribs of the thrombectomy stent can be selected from 0.02mm to 0.2mm, preferably 0.05mm to 0.08mm.
同样地，所述支撑筋的横截面可以是圆形的、椭圆形的或者是长方形等，支撑筋的横截面优选为长方形，支撑筋的宽度可选为0.02mm～0.2mm，优选为0.05mm～0.08mm。所述支撑筋的厚度可选为0.02mm～0.2mm。优选为0.05mm～0.08mm。当支撑筋与取栓支架的筋条为一体成型件时，支撑筋横剖面的尺寸与筋条的相同。通过合理设计取栓支架的筋条和/或支撑筋的尺寸，可以增强取栓支架的强度，但本发明不限于此，其他数值的取栓支架的宽度与厚度均属于本发明的保护范围之内。Similarly, the cross-section of the support rib can be circular, elliptical or rectangular, etc. The cross-section of the support rib is preferably rectangular, and the width of the support rib can be selected to be 0.02mm~0.2mm, preferably 0.05mm~0.08mm. The thickness of the support rib can be selected to be 0.02mm~0.2mm. Preferably, it is 0.05mm~0.08mm. When the support rib and the rib of the thrombectomy bracket are an integrally formed part, the size of the cross-section of the support rib is the same as that of the rib. The strength of the thrombectomy bracket can be enhanced by reasonably designing the size of the ribs and/or support ribs of the thrombectomy bracket, but the present invention is not limited to this, and other values of the width and thickness of the thrombectomy bracket are within the protection scope of the present invention.
在本发明的各个附图中，各个部件的尺寸关系仅为示例，而不作为本发明之间的限制。具体地，各个部件的尺寸可以根据需要选择设定，均属于本发明的保护范围之内。以上内容是结合具体的优选实施方式对本发明所作的进一步详细说明，不能认定本发明的具体实施只局限于这些说明。对于本发明所属技术领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干简单推演或替换，都应当视为属于本发明的保护范围。In the various drawings of the present invention, the dimensional relationship of each component is only an example and is not intended to be a limitation of the present invention. Specifically, the size of each component can be selected and set as needed, all of which fall within the scope of protection of the present invention. The above content is a further detailed description of the present invention in conjunction with a specific preferred embodiment, and it cannot be determined that the specific implementation of the present invention is limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, without departing from the concept of the present invention, several simple deductions or substitutions can be made, all of which should be deemed to fall within the scope of protection of the present invention.
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| CN202111565257.8AActiveCN114052827B (en) | 2021-11-30 | 2021-12-20 | Thrombus taking-out device |
| CN202280005885.7APendingCN120379603A (en) | 2021-11-30 | 2022-11-25 | Thrombus taking-out device |
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| CN202280005885.7APendingCN120379603A (en) | 2021-11-30 | 2022-11-25 | Thrombus taking-out device |
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