CN113974821A - A positioning-guided ablation probe - Google Patents

Abstract

Translated fromChinese

本发明公开了一种定位导向消融探针，包括消融探针本体，消融探针本体包括导向穿刺探头、弹簧管、导向连接件、导杆、导向操控装置和消融电极，导向穿刺探头、弹簧管和导杆依次连接，导向连接件设于弹簧管内，导向操控装置通过导向连接件调整导向穿刺探头的穿刺路径并控制弹簧管的弹性应变调整探针穿刺力，消融电极均匀分布于弹簧管及导杆的外周侧。本定位导向消融探针能够在保证穿刺力的情况下，控制穿刺消融针的穿刺路径发生偏转，使其精确到达预期目标穿刺位置；能够根据消融组织形态选择治疗电极，实现更加彻底与适形治疗目的。本发明有助于降低医生穿刺手术的难度，减少穿刺时间，提高消融效率与治疗率，同时也有助于微创消融技术的推广。The invention discloses a positioning and guiding ablation probe, comprising an ablation probe body. The ablation probe body includes a guiding puncture probe, a spring tube, a guiding connector, a guiding rod, a guiding control device and an ablation electrode. The guiding puncture probe and the spring tube It is connected with the guide rod in sequence, the guide connector is arranged in the spring tube, the guide control device adjusts the puncture path of the guide puncture probe through the guide connector and controls the elastic strain of the spring tube to adjust the puncture force of the probe, and the ablation electrodes are evenly distributed on the spring tube and the guide. the outer peripheral side of the rod. The positioning guide ablation probe can control the deflection of the puncture path of the puncture ablation needle under the condition of ensuring the puncture force, so that it can accurately reach the expected target puncture position; the treatment electrode can be selected according to the shape of the ablation tissue to achieve more thorough and conformal treatment Purpose. The invention helps to reduce the difficulty of the doctor's puncture operation, reduces the puncture time, improves the ablation efficiency and the treatment rate, and also helps to popularize the minimally invasive ablation technology.

Description

Positioning and guiding ablation probe

Technical Field

The invention belongs to the technical field of biomedical engineering, and particularly relates to a positioning and guiding ablation probe.

Background

With the development of science and technology, in particular the progress of medical imaging technology such as nuclear magnetic resonance imaging, ultrasonic imaging and the like, minimally invasive treatment operations such as radio frequency ablation, microwave ablation, nano knife and the like are developed greatly. The existing minimally invasive ablation method mainly adopts percutaneous puncture to enter target tissues, doctors are limited by conditions of bones, visceral organs and the like at puncture positions during operation, the posture characteristics of patients cannot be well mastered, particularly, the existing percutaneous puncture positions cannot be punctured completely, so that the operation difficulty of the doctors is improved, and the doctors are difficult to insert a puncture ablation probe into the optimal position for evaluation by the doctors. In addition, most ablation tissues have irregularity, so that the ablation difficulty is increased, incomplete ablation is easy to cause, and the expected optimal treatment effect cannot be achieved.

Disclosure of Invention

In view of the above, an object of the present invention is to provide a positioning and guiding ablation probe, which can change a puncture path during a probe puncture process, so that the ablation probe reaches a proper ablation position, and simultaneously select a corresponding ablation electrode on the probe to work, so as to perform conformal ablation on tissue to achieve more thorough ablation, so as to solve the deficiencies in the prior art.

In order to achieve the purpose, the invention is realized by the following technical scheme:

the utility model provides a location direction melts probe, including melting the probe body, melt the probe body and include direction puncture probe, spring pipe, direction connecting piece, guide arm, direction controlling device and melt the electrode, the direction puncture probe the spring pipe with the guide arm connects gradually, the direction connecting piece is located in the spring pipe, the direction controlling device passes through the direction connecting piece adjustment the puncture route of direction puncture probe and control the elasticity of spring pipe meets an emergency and adjusts the puncture power of direction puncture probe, melt electrode evenly distributed in the spring pipe reaches the periphery side of guide arm.

The positioning and guiding ablation probe is characterized in that the guiding connecting piece is 4 metal guide wires, and one ends of the 4 metal guide wires are respectively connected to four positions of the circular section of the tail end of the guiding conical probe.

The positioning and guiding ablation probe comprises 4 groups of screw knobs and displacement screws which are in threaded connection, the displacement screws are connected with 4 metal guide wires in a one-to-one correspondence mode, and the linear motion of the displacement screws is realized by rotating the screw knobs, so that the corresponding metal guide wires are driven to generate tensile force in the corresponding direction on the guiding puncture probe.

The ablation probe with the positioning guide function, wherein the guide control device is connected to the tail end of the guide rod, and the displacement of the displacement screw rod generates pulling force on the metal guide wire which is distributed along the axial direction of the guide puncture probe.

The positioning and guiding ablation probe is characterized in that the displacement screws are of a hollow structure, 4 displacement screws are mutually nested, and the outer diameter of the displacement screw positioned at the front stage is smaller than the inner diameter of the displacement screw positioned at the rear stage.

The positioning and guiding ablation probe is characterized in that a puncture angle displacement scale is arranged on the screw knob and used for accurately controlling and adjusting the puncture angle of the probe.

The positioning and guiding ablation probe comprises 4 screw knobs which are connected with 4 metal guide wires in a one-to-one correspondence manner, and the screw knobs are rotated to drive the corresponding metal guide wires to generate tensile force in the corresponding direction on the guiding puncture probe.

The location-oriented ablation probe comprises a flexible insulating sleeve and ablation electrode plates, wherein the spring tube and the guide rod are arranged in the flexible insulating sleeve, and the ablation electrode plates are arranged on the outer surface of the flexible insulating sleeve and are uniformly arrayed.

The positioning and guiding ablation probe is characterized in that 4 ablation electrode plates are uniformly distributed on one circumferential surface of the outer surface of the flexible insulating sleeve, and each ablation electrode plate is independently controlled.

The positioning and guiding ablation probe is characterized in that the ablation probe body is one of a radio frequency ablation probe, a microwave ablation probe, a cryoablation probe and an electroporation ablation probe or a combined ablation probe in any combination.

The technical scheme of the invention has the beneficial effects that:

under the conditions that the position guide ablation probe cannot be punctured through the skin, or cannot reach the expected puncture position of a doctor easily, or is easy to deviate in the puncture process of the doctor and the like, the puncture path of the puncture ablation needle can be controlled to deflect under the condition of ensuring the puncture force, so that the puncture path can accurately reach the expected target puncture position; meanwhile, in order to better ablate, a plurality of independently controllable electrode arrays are arranged on the ablation probe, and a treatment electrode can be selected according to the form of the ablated tissue, so that the purpose of more thorough and conformal treatment is achieved. The invention is helpful to reduce the difficulty of the puncture operation of doctors, reduce the puncture time, improve the ablation efficiency and the treatment rate and also is helpful to the popularization of the minimally invasive ablation technology.

Drawings

To further illustrate the above objects, structural features and effects of the present invention, the present invention will be described in detail below with reference to the accompanying drawings.

FIG. 1 is a partial structural diagram of a head end according to a preferred embodiment of the present invention;

FIG. 2 is a schematic structural diagram of a guiding and controlling device according to a preferred embodiment of the present invention;

FIG. 3 is a schematic view of the connection position of a metal guide wire on the circular section of the end of a guide cone probe according to a preferred embodiment of the present invention;

FIG. 4 is a schematic diagram of the overall structure of the head end according to a preferred embodiment of the present invention;

FIG. 5 is a cross-sectional view of the ablation electrode of FIG. 4 taken along A-A;

FIG. 6 is a schematic diagram illustrating the position relationship between the screw knob and the displacement screw according to a preferred embodiment of the present invention;

FIG. 7 is a schematic illustration of different puncture paths in a target ablation region in accordance with a preferred embodiment of the present invention;

FIG. 8 is a schematic structural diagram of another preferred embodiment;

wherein: 1. a guide cone probe; 2. a spring tube; 3. a guide connection member; 4. a guide bar; 5. a guiding control device; 51. a screw knob; 52. a displacement screw; 6. an ablation electrode; 61. a flexible insulating sleeve; 62. an ablation electrode plate; 7. an ablation probe; 8. a wire; 9. and a transmission rod.

Detailed Description

The terms "invention", "invention" and "invention" as used in this specification are intended to refer broadly to all subject matter of any patent claims below in this specification. Statements containing these terms should not be understood to limit the subject matter described herein or to limit the meaning or scope of any patent claims below. Furthermore, this specification does not intend to describe or limit the subject matter covered by any claims of any particular component, paragraph, statement or drawing of this application. The subject matter should be understood with reference to the entire specification, all drawings, and any claims that follow. The invention is capable of other embodiments and of being practiced or of being carried out in other ways. Also, it is to be understood that the phraseology and terminology employed herein is for the purpose of description and should not be regarded as limiting.

The details of the invention will now be discussed with reference to the accompanying drawings, which illustrate the invention by way of example only. In the drawings, similar features or components may be denoted by the same reference numerals.

The use of "including," "comprising," or "comprising" and variations thereof herein is meant to encompass the items listed thereafter and equivalents thereof as well as additional items. Although reference may be made in describing the drawings to the following directions, such as above, below, upward, downward, rearward, bottom, top, front, rear, etc., for convenience, reference is made with respect to the drawings (as normally viewed). These directions are not intended to literally accept or limit the present invention in any manner. Moreover, terms such as "first," "second," "third," and the like are used herein for illustrative purposes and are not intended to indicate or imply importance or significance.

Referring to fig. 1 and 2, the positioning and guiding ablation probe comprises an ablation probe body, wherein the ablation probe body comprises a guidingpuncture probe 1, aspring tube 2, a guiding connectingpiece 3, aguide rod 4, a guidingcontrol device 5 and anablation electrode 6, the guidingpuncture probe 1, thespring tube 2 and theguide rod 4 are sequentially connected, the guiding connectingpiece 3 is arranged in thespring tube 2, and thespring tube 2 adjusts the stress and the puncture force of the ablation probe and controls the direction force when the guidingpuncture probe 1 deflects by controlling the deformation quantity and the deformation direction of the spring. Theguide puncture probe 1 is used for changing a puncture path and transmitting ablation treatment energy, theguide connecting piece 3 is used for adjusting the direction of the probe and transmitting treatment signals, theguide rod 4 is made of medical stainless steel materials and used for receiving theablation electrode 6 and theguide control device 5, and theablation electrode 6 is used for transmitting the ablation treatment energy to tissues for ablation. The guidingcontrol device 5 adjusts the puncture path of the guidingpuncture probe 1 through the guiding connectingpiece 3 and controls the elastic strain of thespring tube 2, and theablation electrodes 6 are uniformly distributed on the outer peripheral sides of thespring tube 2 and theguide rod 4.

In a preferred embodiment of the present application, referring to fig. 2, the guidingconnector 3 is 4 metal wires, one end of each of the 4 metal wires is connected to four positions of the circular cross section of the end of the guidingpuncture probe 1, and the specific connection position is schematically shown in fig. 3. Optionally, each of the metal wires is of an insulated design, has some flexibility, and is capable of transmitting ablation signals.

In other embodiments, the number of metal wires may be more than 4.

With continued reference to fig. 1, 2, and 6, the guidingmanipulation device 5 includes 4 sets ofscrew buttons 51 anddisplacement screws 52 that are connected to each other through screw threads, the displacement screws 52 are connected to 4 metal guide wires in a one-to-one correspondence manner, and the linear motion of the displacement screws 52 is realized by rotating thescrew buttons 51, so as to drive the corresponding metal guide wires to generate a pulling force in a corresponding direction to the guidingpuncture probe 1. Specifically, one end of each metal guide wire is fixed on acorresponding displacement screw 52 of theguide control device 5, and the displacement of thedisplacement screw 52 is adjusted by rotating ascrew knob 51 on theguide control device 5, so that the displacement generated by the displacement screw generates tensile force on one of the metal guide wires, and the stress on the four metal guide wires on the guideconical probe 1 is unbalanced, so that the guideconical probe 1 generates deflection at a certain angle, and the puncture path of the guide conical probe is changed (the condition that the metal guide wires deform under the action of external tensile force is not considered here).

In a further preferred embodiment, theguide steering device 5 is connected to the end of theguide rod 4, so that the positioning and guiding ablation probe is a one-piece structure. In this case, the displacement of thedisplacement screw 52 generates tensile forces distributed along the axial direction of theguide puncture probe 1 on the metal guide wire. The outer surface ofdisplacement screw 52 is a threaded mechanism, wherein the higher the thread density, the higher the precision of the manipulation. Thedisplacement screw 52 is a hollow structure and is used for passing through a metal guide wire, an ablation signal transmission line and the like, the 4 displacement screws 52 are mutually nested, and the outer diameter of thedisplacement screw 52 positioned at the previous stage is smaller than the inner diameter of thedisplacement screw 52 positioned at the next stage, so that the displacement space of thedisplacement screw 52 during movement can be ensured. It will be appreciated that the hollow structure ofdisplacement screw 52 may be formed by any suitable process, such as drilling, in-situ casting, or additive manufacturing (e.g., 3D printing).

In other embodiments, the guiding and manipulatingdevice 5 can be remotely controlled at the junction of the ablation instrument and the probe connection wire, or automatically manipulated using an electronically controlled motor.

Thescrew knob 51 is provided with puncture angle displacement scales, so that a doctor can know the offset of the guide probe conveniently during operation.

Referring to fig. 4 and 5, theablation electrode 6 includes a flexible insulatingsleeve 61 and anablation electrode pad 62. The positioning and guiding ablation probe is firstly sleeved with a flexible insulatingsleeve 61 before entering an effective ablation area, wherein part or all of thespring tube 2 and theguide rod 4 are also arranged in the flexible insulatingsleeve 61, so that the flexible insulating sleeve and theablation electrode plate 62 have insulativity, and meanwhile, thespring tube 2 can be elastically deformed correspondingly in the flexible insulatingsleeve 61 to generate elastic stress. Theablation electrode plates 62 are arranged on the outer surface of the flexible insulatingsleeve 61 and are evenly arrayed, eachablation electrode plate 62 is independent of each other and can be independently controlled, and appropriate ablation electrodes can be selected to work according to actual ablation conditions. Furthermore, 4ablation electrode plates 62 are uniformly distributed on one circumferential surface of the outer surface of the flexible insulatingsleeve 61.

In operation, as shown in a target ablation region I of fig. 7, when a probe is punctured, the probe is found to be displaced and shifted, and the direction of theguide puncture probe 1 can be controlled to generate a shift of an angle θ (the angle θ is smaller than 90 degrees), that is, the puncture path thereof can be changed (in the figure, a represents an original path, and b represents a new path), so that the probe is punctured to a target position, and the ablation efficiency is improved.

Before puncture, all metal guide wires of the positioning and guiding ablation probe are in the maximum tension state, and thespring tube 2 is tensioned, so that thespring tube 2 has the maximum stress, the hardness of the probe is maximum, and the positioning and guiding ablation probe can have larger puncture force and can penetrate into tissues percutaneously. After the puncture is carried out, when the puncture position of the probe is deviated, the elastic force of thespring tube 2 is uneven by controlling the displacement of the metal guide wire through the guidingcontrol device 5, namely thescrew knob 51 on the control handle releases the elasticity of thespring tube 2, and the stress deviation is generated, so that the guidingconical probe 1 generates certain angle deviation, the puncture path is changed, and the probe is inserted into the ablation area.

Because the ablation area is an irregular area, when ablation is performed, in order to test the ablation effect, the working mode, the electrode polarity, the actual ablation power of each electrode, the ablation time and the like of the correspondingablation electrode sheet 62 can be controlled, so that conformal treatment can be achieved, and the purpose of more thorough ablation of tissues can be achieved.

In another preferred embodiment, another embodiment of the steering system shown in fig. 8 mainly comprises an ablation probe 7, aguide wire 8, a guide connector 3 (i.e., a metal guide wire), ascrew button 51, and atransmission rod 9. A variation on the above embodiment is that the present embodiment eliminates the displacement screw structure and the steering handle can be positioned at the interface of the instrument and the ablation probe. The ablation signal wire and the metal guide wire are connected into the ablation probe 7 through a channel flexible lead, and 4 screw knobs 51 are adopted to control the metal guide wires in 4 directions respectively in operation, so that the metal guide wires generate displacement, and the needle insertion direction of the ablation probe 7 is controlled. Thetransmission rod 9 is used to adjust the relative position of thescrew knob 51 and to control the deformation of the spring tube in the ablation probe 7.

It should be noted that the ablation probe body of the present invention may be one of a radio frequency ablation probe, a microwave ablation probe, a cryoablation probe, and an electroporation ablation probe, or a combined ablation probe in any combination.

The guide ablation probe realizes that the puncture path can be changed in the puncture process, so that the puncture needle can smoothly reach the puncture position, the puncture time and the puncture frequency of a doctor can be reduced, and accurate puncture can be realized. Meanwhile, the ablation electrodes can be independently controlled by arranging the array, ablation energy can be accurately applied to an ablation tissue area, more thorough ablation is realized, and the ablation operation efficiency and the treatment rate are improved.

While the invention has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and detail may be made therein without departing from the spirit and scope of the invention.

Claims (10)

Translated fromChinese

1.一种定位导向消融探针，其特征在于，包括消融探针本体，所述消融探针本体包括导向穿刺探头(1)、弹簧管(2)、导向连接件(3)、导杆(4)、导向操控装置(5)和消融电极(6)，所述导向圆锥探头(1)、所述弹簧管(2)和所述导杆(4)依次连接，所述导向连接件(3)设于所述弹簧管(2)内，所述导向操控装置(5)通过所述导向连接件(3)调整所述导向圆锥探头(1)的穿刺路径并控制所述弹簧管(2)的弹性应变，所述消融电极(6)均匀分布于所述弹簧管(2)及所述导杆(4)的外周侧。1. A positioning and guiding ablation probe, characterized in that it comprises an ablation probe body, the ablation probe body comprising a guiding puncture probe (1), a spring tube (2), a guiding connector (3), a guide rod ( 4) A guide manipulation device (5) and an ablation electrode (6), the guide cone probe (1), the spring tube (2) and the guide rod (4) are connected in sequence, and the guide connector (3) ) is arranged in the spring tube (2), and the guide control device (5) adjusts the puncture path of the guide cone probe (1) through the guide connector (3) and controls the spring tube (2) The elastic strain of the ablation electrode (6) is evenly distributed on the outer peripheral side of the spring tube (2) and the guide rod (4).2.如权利要求1所述定位导向消融探针，其特征在于，所述导向连接件(3)为4根金属导丝，4根所述金属导丝的一端分别连接于所述导向穿刺探头(1)的末端圆形截面的四个方位处。2 . The positioning and guiding ablation probe according to claim 1 , wherein the guiding connector ( 3 ) is four metal guide wires, and one end of the four metal guide wires is respectively connected to the guiding puncture probe. 3 . (1) at the four orientations of the end circular section.3.如权利要求2所述定位导向消融探针，其特征在于，所述导向操控装置(5)包括4组相互螺纹连接的螺旋钮(51)和位移螺杆(52)，所述位移螺杆(52)一一对应地连接4根所述金属导丝，通过旋转所述螺旋钮(51)实现所述位移螺杆(52)的直线运动，从而带动相应所述金属导丝对所述导向穿刺探头(1)产生相应方向上的拉力。3. The positioning guide ablation probe according to claim 2, characterized in that, the guide manipulation device (5) comprises 4 sets of screw buttons (51) and displacement screws (52) that are threadedly connected to each other, and the displacement screws (52) 52) Connect four of the metal guide wires in a one-to-one correspondence, and realize the linear movement of the displacement screw (52) by rotating the screw knob (51), thereby driving the corresponding metal guide wires to guide the puncture probe. (1) Generate a pulling force in the corresponding direction.4.如权利要求3所述定位导向消融探针，其特征在于，所述导向操控装置(5)连接于所述导杆(4)的末端，所述位移螺杆(52)的位移对所述金属导丝产生沿着所述导向穿刺探头(1)的轴向分布的拉力。4. The positioning guide ablation probe according to claim 3, characterized in that, the guide manipulation device (5) is connected to the end of the guide rod (4), and the displacement of the displacement screw (52) affects the The metal guide wire generates a tensile force distributed along the axial direction of the guiding puncture probe (1).5.如权利要求4所述定位导向消融探针，其特征在于，所述位移螺杆(52)为空心结构，4根所述位移螺杆(52)相互嵌套且位于前一级的所述位移螺杆(52)的外径小于位于后一级的所述位移螺杆(52)的内径。5. The positioning-guided ablation probe according to claim 4, wherein the displacement screw (52) is a hollow structure, and the four displacement screws (52) are nested with each other and located at the displacement of the previous stage The outer diameter of the screw (52) is smaller than the inner diameter of the displacement screw (52) in the latter stage.6.如权利要求2至5中任意一项所述定位导向消融探针，其特征在于，所述螺旋钮(51)上设有穿刺角度位移刻度。6. The positioning-guided ablation probe according to any one of claims 2 to 5, wherein a puncture angle displacement scale is provided on the screw knob (51).7.如权利要求2所述定位导向消融探针，其特征在于，所述导向操控装置(5)包括4个螺旋钮(51)，所述螺旋钮(51)一一对应地连接4根所述金属导丝，通过旋转所述螺旋钮(51)带动相应所述金属导丝对所述导向穿刺探头(1)产生相应方向上的拉力。7. The positioning and guiding ablation probe according to claim 2, characterized in that, the guiding control device (5) comprises four screw buttons (51), and the screw buttons (51) are connected to the four screws correspondingly one by one. The metal guide wire, by rotating the screw knob (51), drives the corresponding metal guide wire to generate a pulling force in the corresponding direction on the guiding puncture probe (1).8.如权利要求1所述定位导向消融探针，其特征在于，所述消融电极(6)包括柔性绝缘套管(61)和消融电极片(62)，所述弹簧管(2)及所述导杆(4)设于所述柔性绝缘套管(61)内，所述消融电极片(62)设于所述柔性绝缘套管(61)的外表面并呈均匀阵列排布。8. The positioning and guiding ablation probe according to claim 1, wherein the ablation electrode (6) comprises a flexible insulating sleeve (61) and an ablation electrode sheet (62), the spring tube (2) and the The guide rod (4) is arranged in the flexible insulating sleeve (61), and the ablation electrode sheets (62) are arranged on the outer surface of the flexible insulating sleeve (61) and are arranged in a uniform array.9.如权利要求8所述定位导向消融探针，其特征在于，所述柔性绝缘套管(61)的外表面一个周面均匀分布有4片所述消融电极片(62)，每片所述消融电极片(62)为独立控制。9. The positioning-guided ablation probe according to claim 8, characterized in that 4 pieces of the ablation electrode pieces (62) are evenly distributed on a peripheral surface of the outer surface of the flexible insulating sleeve (61), and each piece has 4 pieces of the ablation electrode pieces (62). The ablation electrode sheet (62) is independently controlled.10.如权利要求1所述定位导向消融探针，其特征在于，所述消融探针本体为射频消融探针、微波消融探针、冷冻消融探针、电穿孔消融探针中的一种消融探针或任意组合的联合消融探针。10 . The positioning-guided ablation probe according to claim 1 , wherein the ablation probe body is an ablation probe selected from radio frequency ablation probes, microwave ablation probes, cryoablation probes, and electroporation ablation probes. 11 . Probes or any combination of combined ablation probes.

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