Disclosure of Invention
The present invention aims to provide a visual type sampler which is convenient for rapidly separating tumor biopsy samples, so as to solve the above problems in the prior art.
In order to achieve the above purpose, the invention provides a visual sampler convenient for rapidly separating tumor biopsy samples, which comprises a bottom plate, wherein a movable plate is arranged above the bottom plate at intervals, the movable plate is mutually parallel to the bottom plate, two symmetrically distributed adjusting frames are vertically arranged between the bottom plate and the movable plate, the adjusting frames are of telescopic structures, a needle cylinder is installed on the movable plate and close to the center, the bottom end of the needle cylinder slidably penetrates through the bottom plate to extend to the lower part of the bottom plate, the top end of the needle cylinder penetrates through the movable plate to extend to the upper part of the top of the movable plate, the inside of the needle cylinder is of a hollow structure, a slidable piston is arranged in the needle cylinder, the piston is sleeved and matched with the inner wall of the needle cylinder, a sample chamber is arranged at the bottom of the needle cylinder and is positioned below the bottom plate, the sample chamber and the needle cylinder are integrally formed, the inside of the needle cylinder is communicated with the inside of the sample chamber, and a sampling component is installed at the bottom of the sample chamber.
In one embodiment of the invention, a locating hole is formed in the bottom plate and near the center, the bottom end of the needle cylinder penetrates through the locating hole to extend to the lower part of the bottom plate and is connected with the bottom plate in a sliding mode, supports are welded and fixed at the bottom of the bottom plate and near four corners, anti-slip pads are arranged at the bottoms of the supports, and the anti-slip pads are in adhesive fit with the bottoms of the supports. The bottom plate can be supported and fixed through the support, so that the needle cylinder and the sampling assembly can be fixed, and sampling is convenient.
In one embodiment of the invention, a bearing is arranged on the movable plate and near the center, the outer ring of the bearing is fixedly connected with the movable plate, and the inner ring of the bearing is fixedly connected with the needle cylinder. The needle cylinder is conveniently rotated through the bearing, so that the sampling assembly is conveniently driven to rotate for sampling.
In one embodiment of the invention, the adjusting frame comprises a sleeve, the bottom of the sleeve is provided with a movable head, the movable head and the sleeve are integrally formed, the movable head is embedded on the bottom plate and is rotationally connected with the bottom plate, a telescopic pipe which can slide is arranged in the sleeve and is sleeved and matched with the sleeve, the top end of the telescopic pipe is fixedly connected with the bottom surface of the movable plate, the bottom of the telescopic pipe is provided with a conical thread head, the outer side of the conical thread head is provided with a C-shaped movable eccentric sleeve, the movable eccentric sleeve is in threaded connection with the conical thread head, and an arc-shaped block is arranged on the outer wall of the movable eccentric sleeve and close to the edge. The needle cylinder can be driven to move up and down through the adjusting frame, so that the needle cylinder can drive the sampling assembly to move for sampling.
In one embodiment of the invention, a plurality of scale marks which are uniformly distributed are arranged on the outer surface of the needle cylinder, a sealing plug is arranged at the top of the needle cylinder, the sealing plug is in threaded connection with the inner wall of the top of the needle cylinder, a movable disc is arranged at the outer side of the needle cylinder and close to the top end of the needle cylinder, the movable disc and the needle cylinder are integrally formed, a vertical rocker is arranged at the top surface of one end of the movable disc, which is far away from the needle cylinder, and the rocker and the movable disc are integrally formed. The rocking bar rotates to enable the movable disc to rotate and can drive the needle cylinder to rotate, so that the sampling assembly rotates to sample.
In one embodiment of the invention, a sealing ring is arranged on the outer side of the piston, the sealing ring is in sleeved fit with the piston, a piston rod is arranged at the top of the piston, the piston rod and the piston are integrally formed, the top end of the piston rod penetrates through the sealing plug to extend to the upper side of the sealing plug, the piston rod is in sliding connection with the sealing plug, a spring is arranged between the piston and the sealing plug, and the spring is sleeved on the outer side of the piston rod. After the sampling is completed, the piston is pulled to enable the inside of the needle cylinder to form negative pressure, so that tumor tissues of the needle tube are sucked into the sample chamber, and the tissues are conveniently taken out through the sample chamber.
In one embodiment of the invention, a clamping groove is formed in the front side of the sample chamber and close to the right side edge, a movable cover is arranged on the right side of the sample chamber, one side edge of the movable cover is hinged to one side edge of the sample chamber, a clamping block is arranged on the movable cover and close to the front side edge, the clamping block is in clamping fit with the clamping groove, and a slope surface is arranged in the sample chamber and close to the bottom end. The tumor tissue in the sample chamber can slide to the movable cover through the slope surface, so that the tumor tissue can be conveniently separated.
In one embodiment of the invention, a connector is arranged at the bottom of the sample chamber, the connector and the sample chamber are integrally formed, a threaded section is arranged on the inner wall of the connector, a one-way valve is arranged on the outer side of the connector, and the bottom of the connector is in threaded connection with the sampling assembly. The one-way valve enables the tumor tissue to flow only to the inside of the sample chamber, and the tumor tissue is prevented from flowing into the needle tube when being separated.
In one embodiment of the invention, the sampling assembly comprises a needle tube, the needle tube is of a hollow structure with an opening at the top, a threaded joint is arranged on the needle tube and near the top end, the threaded joint is in threaded connection with the connector, a needle head is arranged at the bottom of the needle tube, and the needle head and the needle tube are integrally formed. The needle tube is conveniently inserted into the tumor through the needle head, so that sampling is convenient.
In one embodiment of the invention, annular blades distributed in an annular array are arranged on the circumferential outer wall of the needle tube and near the bottom end, a plurality of barb blades distributed uniformly are arranged on the circumferential outer wall of the needle tube and above the annular blades, sampling ports are arranged on the needle tube and near the annular blades and the barb blades, and the sampling ports are communicated with the interior of the needle tube. The tumor tissue sample is scraped through rotating the annular blade and the barb blade, so that the tumor tissue can be scraped into the needle tube rapidly, and the sample is sampled rapidly.
In conclusion, by adopting the technical scheme, the invention has the beneficial effects that:
1. According to the invention, the bottom plate and the adjusting frame are arranged, so that the needle cylinder can be fixed and supported, and when sampling is carried out, the movable plate is pushed downwards, so that the telescopic pipe slides in the sleeve, the needle cylinder can drive the sampling assembly to stably move downwards, unnecessary wounds to a patient caused by shaking and skewing the sampling assembly when the sampling assembly moves are avoided, and the health of the patient is guaranteed.
2. When the sampling assembly is pulled out, the barb blade can sample the tumor tissue near the needle tube, so that the sampler can obtain enough tumor living tissue, and the situation that the sample is insufficient and needs to be sampled repeatedly is avoided.
3. When the tumor biopsy sample is separated, the piston rod drives the piston to move, so that negative pressure is formed in the needle cylinder, tumor tissues in the needle cylinder are sucked into the sample chamber, and then the movable cover is opened, so that the tumor tissues can be rapidly separated from the sample chamber, the tumor tissues are prevented from being polluted by bacteria after being stored for a long time, and the tumor biopsy is convenient to carry out.
Detailed Description
The following detailed description of embodiments of the invention is, therefore, to be taken in conjunction with the accompanying drawings, and it is to be understood that the scope of the invention is not limited to the specific embodiments.
Throughout the specification and claims, unless explicitly stated otherwise, the term "comprise" or variations thereof such as "comprises" or "comprising", etc. will be understood to include the stated element or component without excluding other elements or components.
Referring to fig. 1-2, a preferred embodiment of the present invention includes a bottom plate 1, a movable plate 2 is disposed above the bottom plate 1 at intervals, the movable plate 2 is parallel to the bottom plate 1, two symmetrically distributed adjusting frames 3 are vertically disposed between the bottom plate 1 and the movable plate 2, the adjusting frames 3 are of a telescopic structure, a syringe 4 is installed on the movable plate 2 and near the center, the bottom end of the syringe 4 slidably penetrates the bottom plate 1 to extend to the lower side of the bottom plate 1, the top end of the syringe 4 penetrates the movable plate 2 to extend to the upper side of the top of the movable plate 2, the inside of the syringe 4 is of a hollow structure, a slidable piston 5 is disposed in the syringe 4, the piston 5 is in socket fit with the inner wall of the syringe 4, a sample chamber 6 is disposed at the bottom of the syringe 4 and below the bottom plate 1, the sample chamber 6 is integrally formed with the syringe 4, and the inside of the syringe 4 is communicated with the inside of the sample chamber 6, and a sampling assembly 7 is installed at the bottom of the sample chamber 6.
By moving the syringe 4 downwards, the sampling component 7 is driven to penetrate into tumor tissues, so that the sampling component 7 samples the tumor tissues; by moving the piston 5 upwards, negative pressure is generated in the syringe 4, so that the tumor tissue sample is taken by the sampling assembly 7 and flows into the sample chamber 6, the tumor tissue sample can be taken out of the sample chamber 6 quickly, and the pollution caused by long time for taking out the tumor tissue sample is effectively prevented.
Referring to fig. 3 to 5, in a preferred embodiment, a positioning hole 11 is formed on the bottom plate 1 near the center, the bottom end of the needle cylinder 4 extends to the lower part of the bottom plate 1 through the positioning hole 11 and is slidably connected with the bottom plate 1, and brackets 12 are welded and fixed at the bottom of the bottom plate 1 near four corners. The bottom plate 1 can be supported and fixed through the bracket 12, so that the needle cylinder 4 and the sampling assembly 7 can be fixed, and sampling is convenient.
In the above scheme, the bottoms of the brackets 12 are provided with the anti-slip pads 13, and the anti-slip pads 13 are bonded and matched with the bottoms of the brackets 12. The anti-slip pad 13 is made of rubber materials, and the rubber materials are good in protection performance and wear resistance, so that the support 12 can be effectively protected, and meanwhile the support 12 is prevented from sliding in the sampling process to influence sampling.
In a preferred embodiment, the adjusting frame 3 comprises a sleeve 31, a movable head 311 is arranged at the bottom of the sleeve 31, the movable head 311 and the sleeve 31 are integrally formed, the movable head 311 is embedded on the bottom plate 1 and is rotationally connected with the bottom plate 1, a slidable telescopic tube 32 is arranged in the sleeve 31, the telescopic tube 32 is in sleeved connection with the sleeve 31, the top end of the telescopic tube 32 is fixedly connected with the bottom surface of the movable plate 2, the telescopic tube 32 can slide in the sleeve 31, so that the adjusting frame 3 stretches and contracts to drive the needle cylinder 4 to move up and down, and the needle cylinder 4 can drive the sampling assembly 7 to move to sample.
In addition, the bottom of flexible pipe 32 is provided with toper screw thread head 321, and the outside of toper screw thread head 321 is equipped with the movable eccentric sleeve 322 of C, and movable eccentric sleeve 322 and toper screw thread head 321 threaded connection are provided with arc piece 323 on the outer wall of movable eccentric sleeve 322 and be close to the edge, and the inner wall of sleeve pipe 31 is laminated with the lateral surface of arc piece 323. When the sleeve 31 is rotated, the arc-shaped block 323 can be extruded, so that the C-shaped movable eccentric sleeve 322 is contracted, the movable eccentric sleeve 322 is tightly connected with the conical threaded head 321, the sleeve 31 and the telescopic pipe 32 are fixed, the adjusting frame 3 is prevented from moving during sampling, and sampling is facilitated.
Referring to fig. 6 to 8, in a preferred embodiment, a bearing 21 is provided on the movable plate 2 near the center, an outer ring of the bearing 21 is fixedly connected to the movable plate 2, and an inner ring of the bearing 21 is fixedly connected to the cylinder 4. The needle cylinder 4 is conveniently rotated through the bearing 21, so that the sampling assembly 7 is conveniently driven to rotate for sampling.
In a preferred embodiment, be provided with a plurality of evenly distributed's scale mark 41 on the surface of cylinder 4, can observe the distance that cylinder 4 moved down through scale mark 41 to conveniently control the displacement of sampling subassembly 7, avoid needle tube 71 to puncture too much and cause the damage to other tissues, the top of cylinder 4 is equipped with sealing plug 42, sealing plug 42 and the inner wall threaded connection at cylinder 4 top can seal at cylinder 4's top through sealing plug 42, avoid the dust to get into the inside of cylinder 4.
In the above scheme, the outside of the needle cylinder 4 and the position close to the top end are provided with the movable disc 43, the movable disc 43 and the needle cylinder 4 are integrally formed, the top surface of one end of the movable disc 43 far away from the needle cylinder 4 is provided with the vertical rocker 44, the rocker 44 and the movable disc 43 are integrally formed, the movable disc 43 rotates through the rotation of the rocker 44, and the needle cylinder 4 can be driven to rotate, so that the sampling assembly 7 rotates to sample.
In addition, the syringe 4 is made of a high polymer polypropylene material, and the polypropylene material has good transparency, so that the inside of the syringe 4 can be conveniently observed.
In a preferred embodiment, a sealing ring 51 is arranged on the outer side of the piston 5, the sealing ring 51 is in sleeve joint with the piston 5, the sealing between the piston 5 and the inner wall of the needle cylinder 4 can be realized through the sealing ring 51, and after the piston 5 is conveniently moved, negative pressure is formed in the needle cylinder 4; the top of piston 5 is provided with piston rod 52, and piston rod 52 and piston 5 integrated into one piece, and the top of piston rod 52 runs through sealing plug 42 and extends to the top of sealing plug 42, and piston rod 52 and sealing plug 42 sliding connection. When the sampling assembly 7 is used for sampling, the piston 5 is pulled to form negative pressure in the syringe 4, so that a tumor tissue sample in the sampling assembly 7 is sucked into the sample chamber 6, and the tissue is conveniently taken out through the sample chamber 6.
In the above scheme, the spring 53 is arranged between the piston 5 and the sealing plug 42, the spring 53 is sleeved on the outer side of the piston rod 52, and after the piston rod 52 is loosened, the elastic action of the spring 53 can push the piston 5 to move, so that the piston 5 is quickly restored, and sampling is convenient.
In a preferred embodiment, the front side of the sample chamber 6 and the position close to the right side edge are provided with the clamping groove 61, the right side of the sample chamber 6 is provided with the movable cover 62, one side edge of the movable cover 62 is hinged to one side edge of the sample chamber 6, a clamping block 63 is arranged on the movable cover 62 and close to the front side edge, the clamping block 63 is clamped and matched with the clamping groove 61, so that the movable cover 62 can be opened or closed, a tumor sample can be conveniently taken out, a slope surface is arranged in the sample chamber 6 and close to the bottom end, and the tumor tissue sample in the sample chamber 6 can slide to the movable cover 62 through the slope surface, so that the tumor tissue can be conveniently separated.
In the above scheme, the bottom of sample room 6 is equipped with connector 64, connector 64 and sample room 6 integrated into one piece, is provided with the screw thread section on the inner wall of connector 64, and check valve 65 is installed in the outside of connector 64, and the bottom of connector 64 and sampling assembly 7 threaded connection, check valve 65 make the tumour tissue can only flow to the inside of sample room 6, in the needle tube 71 when avoiding tumour tissue separation.
Referring to fig. 9, in a preferred embodiment, the sampling assembly 7 comprises a needle tube 71, the needle tube 71 is a hollow structure with an opening at the top, a threaded joint 711 is arranged on the needle tube 71 near the top, the threaded joint 711 is in threaded connection with the connector 64, a needle 72 is arranged at the bottom of the needle tube 71, and the needle 72 and the needle tube 71 are integrally formed. The needle tube 71 is conveniently inserted into the tumor through the needle 72, thereby facilitating sampling.
In the above scheme, the annular edge 73 distributed in an annular array is arranged on the circumferential outer wall of the needle tube 71 and near the bottom end, a plurality of uniformly distributed barb edges 74 are arranged on the circumferential outer wall of the needle tube 71 and above the annular edge 73, sampling ports are formed in the needle tube 71 and near the annular edge 73 and the barb edges 74, and the sampling ports are communicated with the inside of the needle tube 71. By rotating the needle tube 71, the annular blade 73 and the barb blade 74 are rotated, so that a tumor tissue sample is scraped, and the tumor tissue sample can be scraped into the needle tube 71 rapidly, so that sampling is performed rapidly. Wherein, the diameter at needle 72 top is slightly greater than the diameter of needle tubing 71, conveniently brings annular sword 73 and barb sword 74 inside the tumour, avoids annular sword 73 and barb sword 74 to scratch other tissues to the sample is conveniently taken.
The visual sampler convenient for quickly separating tumor biopsy samples is characterized in that when in use:
When sampling is carried out, firstly, the movable bracket 12 drives the bottom plate 1 to move, so that the bottom plate 1 moves above a tumor, and the rotary sleeve 31 releases the fixation of the telescopic tube 32; then the movable plate 2 is pushed downwards, the movable plate 2 drives the needle cylinder 4 to move downwards, and the needle cylinder 4 drives the sampling assembly 7 to move downwards, so that the sampling assembly 7 is inserted into tumor tissues; then, the sleeve 31 is rotated to enable the conical thread head 321 to be in threaded connection with the movable eccentric sleeve 322, so that the sleeve 31 and the telescopic tube 32 are locked to prevent the adjusting frame 3 from moving; then, the rocker 44 is rotated to enable the needle cylinder 4 to drive the annular blade 73 to rotate, after the annular blade 73 rotates, tumor tissues are scraped into the needle cylinder 71, then the bottom plate 1 is moved upwards to drive the movable plate 2 and the needle cylinder 4 to move upwards, so that the needle cylinder 71 is gradually separated from the tumor tissues, at the moment, the barb blade 74 moves upwards to enable the tumor tissues near the needle cylinder 71 to be woven into the needle cylinder 71, and when the needle cylinder 71 is completely separated from a patient, sampling can be completed.
When the sample is separated, the piston rod 52 is pulled upwards, so that the piston rod 52 drives the piston 5 to move upwards, the inside of the needle cylinder 4 forms a negative pressure state, and tumor tissues inside the needle cylinder 71 are sucked into the sample chamber 6; then the movable cover 62 is opened, then the piston rod 52 is slowly released, the elastic action of the spring 53 can push the piston 5 to move, so that the piston 5 moves towards the sample chamber 6, and the tumor biopsy sample is extruded out of the sample chamber 6, so that the tumor biopsy sample is quickly separated.
The foregoing descriptions of specific exemplary embodiments of the present invention are presented for purposes of illustration and description. It is not intended to limit the invention to the precise form disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain the specific principles of the invention and its practical application to thereby enable one skilled in the art to make and utilize the invention in various exemplary embodiments and with various modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the claims and their equivalents.