CN113881558A - Nucleic acid sample heating instrument - Google Patents

Abstract

The invention discloses a nucleic acid sample heating instrument, which comprises a shell, wherein a circuit board assembly, a storage battery and an electric heating block are fixed inside the shell, a temperature sensor is embedded inside the electric heating block, the storage battery, the electric heating block and the temperature sensor are all electrically connected with the circuit board assembly, and a button group used for triggering a button group positioned on the circuit board assembly is arranged on the shell; the electric heating block is provided with a plurality of jacks for inserting containers storing nucleic acid samples, the upper end of the shell is provided with through holes which are in one-to-one correspondence with the jacks, and each through hole is used for allowing the container to pass through so that the container can be inserted into the jacks at the corresponding positions; the invention has the advantages of small volume, convenient carrying and convenient operation, thus, a tester can carry the nucleic acid sample heating instrument with him and can rapidly heat the nucleic acid sample at any time and any place, thereby bringing convenience to the heating of the nucleic acid sample.

Description

Nucleic acid sample heating instrument

Technical Field

The invention relates to the technical field of nucleic acid sample processing devices, in particular to a nucleic acid sample heating instrument.

Background

The nucleic acid sample heating instrument is used for heating collected nucleic acid samples, the nucleic acid sample heating instrument used in the market is generally placed in a detection laboratory, and the nucleic acid sample heating instrument used in the market has the defects of large volume, inconvenience in carrying and inconvenience in operation, so that a detection person cannot carry the nucleic acid sample heating instrument with him, and the defect that the detection person cannot rapidly heat the nucleic acid samples anytime and anywhere exists.

Disclosure of Invention

Aiming at the defects of the prior art, the invention provides the nucleic acid sample heating instrument which has the advantages of small volume, convenience in carrying and convenience in operation, so that a tester can carry the nucleic acid sample heating instrument with him and can rapidly heat the nucleic acid sample at any time and any place.

The nucleic acid sample heating instrument comprises a shell, wherein a circuit board assembly, a storage battery and an electric heating block are fixed inside the shell, a temperature sensor is embedded inside the electric heating block, the storage battery, the electric heating block and the temperature sensor are all electrically connected with the circuit board assembly, and a button group used for triggering a button group positioned on the circuit board assembly is arranged on the shell; the electric heating block is provided with a plurality of jacks for inserting the containers storing the nucleic acid samples, the upper end of the shell is provided with through holes corresponding to the jacks one to one, and each through hole is used for allowing the containers to pass so that the containers can be inserted into the jacks at the corresponding positions conveniently.

The nucleic acid sample heating instrument comprises a shell, wherein a concave cavity is formed in the upper end of the shell, a container penetrates through a through hole and is inserted into an insertion hole, the concave cavity is used for accommodating a cover body of the container, a heating cover used for sealing the concave cavity is rotatably connected into the concave cavity, an electric heating piece is attached to the lower surface of the heating cover, and the electric heating piece is electrically connected with a circuit board assembly; through the arrangement of the heating cover and the electric heating sheet, after the electric heating sheet is electrified to generate heat, the electric heating sheet can heat the cover body of the container positioned in the concave cavity, so that condensed water formed on the cover body of the container after the nucleic acid sample in the container is evaporated can be avoided, and the nucleic acid sample can be prevented from being subjected to non-specific amplification due to the reduction of the liquid amount to cause false positive; in addition, when the temperature control circuit works, the temperature of the electric heating sheet is between 75 ℃ and 80 ℃, the temperature control of the electric heating sheet is realized by electrifying the electric heating sheet at intervals, namely the electric heating sheet is powered off after being electrified for a period of time, the electric heating sheet is powered on after being powered off for a period of time, the power on-off time of the electric heating sheet is set in a control module in the circuit board assembly according to theoretical calculation, and the temperature control of the electric heating sheet does not need to be too accurate, so that a temperature sensor does not need to be used.

The invention discloses a nucleic acid sample heating instrument, wherein a partition board is arranged in a shell and used for separating a circuit board assembly and an electric heating block; through the arrangement of the partition plate, the partition plate can realize the isolation of the circuit board assembly and the electric heating block, so that the heat generated by the electric heating block can be effectively prevented from being transferred to the circuit board assembly, and the influence on the normal work of the circuit board assembly is avoided; in addition, the storage battery and the electric heating block are also separated by a partition plate, namely the storage battery is positioned on one side of the circuit board assembly; in addition, through the setting of baffle, can effectively avoid the scattering and disappearing of the heat of heating the piece.

The nucleic acid sample heating instrument comprises a circuit board assembly, a shell, a heating element and a heating element, wherein the circuit board assembly is provided with a display screen; through the arrangement of the display screen, the display screen can display the temperature value of the electric heating block, the residual heating time of the nucleic acid sample in the container and other information, namely, a user can intuitively know the key data information of the invention.

The invention discloses a nucleic acid sample heating instrument, wherein an indicator lamp group is arranged on a circuit board assembly, a light-transmitting hole group is arranged at the upper end of a shell, and each light-transmitting hole in the light-transmitting hole group is respectively arranged corresponding to one indicator lamp in the indicator lamp group; through the arrangement of the indicator lamp group, one indicator lamp in the indicator lamp group is used as a charging indicator lamp, and the other indicator lamps in the indicator lamp group are used as running indicator lamps, so that a user can judge the charging condition and the running condition of the intelligent charging lamp by observing the on-off or luminous color of the indicator lamp group.

The nucleic acid sample heating instrument comprises a shell, wherein a loudspeaker is fixed on the inner wall of the shell, a plurality of sound outlet holes are formed in the shell at the position of the loudspeaker, and the loudspeaker is electrically connected with a circuit board assembly; through the arrangement of the horn, after the nucleic acid sample in the container is heated, the circuit board assembly can control the horn to sound or send out voice prompt information to inform a user that the nucleic acid sample is heated, so that convenience can be brought to the user.

The nucleic acid sample heating instrument comprises a circuit board assembly, a charging socket, a shell and a heating device, wherein the circuit board assembly is provided with the charging socket; a power switch is fixed on the side wall of the shell and is electrically connected with the circuit board assembly; through the arrangement of the charging socket, after the charging socket is connected with the power adapter, the power adapter can charge the storage battery in the invention; the power switch is arranged, and the power switch can be operated to conveniently control the on or off of the invention.

The nucleic acid sample heating instrument comprises a shell, a first lamp plate, a second lamp plate, a camera module, a circuit board assembly and a plurality of jacks, wherein the shell is positioned below an electric heating block, the first lamp plate is provided with light projecting lamp beads which are vertically and correspondingly arranged with the jacks one by one, the inner wall of the shell is fixed with the camera module, one side of each jack is provided with an opening, each opening faces one side of the camera module, and the first lamp plate and the camera module are electrically connected with the circuit board assembly; through the setting of first lamp plate, after the electric heat piece is accomplished the heating of the nucleic acid sample in the container, every projection lamp pearl that is located on first lamp plate all can be lighted, the projection lamp pearl is lighted the back, every projection lamp pearl can light the container on the corresponding position respectively, simultaneously under the image recognition of camera module, circuit board assembly can judge the positive and negative condition of every nucleic acid sample according to the image data that camera module obtained, and show the testing result on the display screen.

The nucleic acid sample heating instrument comprises a shell, a first lamp panel, a second lamp panel, a plurality of jacks and a plurality of light-projecting lamp beads, wherein the shell at the position of each end of the first lamp panel is provided with a sliding chute; at least one screw penetrates through the first lamp panel, the screw is in threaded connection with the first lamp panel, the end part of the screw is abutted against the shell, and the first lamp panel and the shell are locked through the screw; after adopting this kind of structure, when assembling first lamp plate for first lamp plate slides along the spout and can adjust the front and back position of light projector lamp pearl for the jack, so, can with the position control of first lamp plate to suitable position, after the position control of first lamp plate is accomplished, screws up the screw and can make first lamp plate and casing locking.

The nucleic acid sample heating instrument comprises a shell, wherein a second lamp plate is fixed in the shell, the second lamp plate is provided with indicating lamp beads the number of which is the same as that of jacks, the shell is provided with indicating lamp holes corresponding to the indicating lamp beads one by one, and the second lamp plate is electrically connected with a circuit board assembly; through the setting of second lamp plate, and the quantity that is located the instruction lamp pearl on the second lamp plate is the same with the quantity of jack, when circuit board assembly passes through the camera module and judges certain nucleic acid sample for positive, the instruction lamp pearl that corresponds with this nucleic acid sample can send ruddiness, when circuit board assembly passes through the camera module and judges certain nucleic acid sample for negative, the instruction lamp pearl that corresponds with this nucleic acid sample can send the green glow, so, the user can conveniently judge the negative and positive condition of every nucleic acid sample through the luminous colour of instruction lamp pearl.

The invention has the advantages of small volume, convenient carrying and convenient operation, thus, a tester can carry the nucleic acid sample heating instrument with him and can rapidly heat the nucleic acid sample at any time and any place, thereby bringing convenience to the heating of the nucleic acid sample.

Drawings

The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the application and together with the description serve to explain the application and not to limit the application. In the drawings:

FIG. 1 is a schematic representation of a first perspective view of the present invention using the protocol of example 1;

FIG. 2 is a second perspective view of the present invention using the embodiment of example 1;

FIG. 3 is a schematic view of a first partially exploded perspective view of the present invention employing the scheme of example 1;

FIG. 4 is a second partially exploded perspective view of the present invention utilizing the embodiment of example 1;

FIG. 5 is a partially exploded perspective view of the present invention, with part of the structure removed, according to the embodiment of example 1;

FIG. 6 is a schematic representation of a first perspective view of the present invention using the protocol of example 2;

FIG. 7 is a second perspective view of the present invention using the embodiment of example 2;

FIG. 8 is a schematic view of a first partially exploded perspective view of the present invention employing the protocol of example 2;

FIG. 9 is a second partially exploded perspective view of the present invention utilizing the embodiment of example 2;

FIG. 10 is a third partially exploded perspective view of the present invention utilizing the embodiment of example 2.

Detailed Description

In the following description, for purposes of explanation, numerous implementation details are set forth in order to provide a thorough understanding of the various embodiments of the present invention. It should be understood, however, that these implementation details are not to be interpreted as limiting the invention. That is, in some embodiments of the invention, such implementation details are not necessary. In addition, some conventional structures and components are shown in simplified schematic form in the drawings.

In addition, the descriptions related to the first, the second, etc. in the present invention are only used for description purposes, do not particularly refer to an order or sequence, and do not limit the present invention, but only distinguish components or operations described in the same technical terms, and are not understood to indicate or imply relative importance or implicitly indicate the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present invention.

Example 1

As shown in fig. 1-5, the nucleic acid sample heating instrument of the present invention comprises acasing 1, acircuit board assembly 2, astorage battery 3 and anelectric heating block 4 are fixed inside thecasing 1, a temperature sensor is embedded inside theelectric heating block 4, thestorage battery 3, theelectric heating block 4 and the temperature sensor are all electrically connected with thecircuit board assembly 2, and a button set 11 for triggering abutton set 21 located on thecircuit board assembly 2 is installed on thecasing 1; theelectric heating block 4 is provided with a plurality ofjacks 41 for inserting containers storing nucleic acid samples, the upper end of theshell 1 is provided with throughholes 12 corresponding to thejacks 41 one by one, and each throughhole 12 is used for allowing a container to pass through so that the container can be inserted into thejacks 41 at corresponding positions; the button group can trigger the button group to adjust parameters such as heating time, heating temperature and the like of the nucleic acid sample in the container; in addition, the container for storing the nucleic acid sample used in the present invention is an EP tube, that is, a transparent centrifuge tube.

The upper end of theshell 1 is provided with aconcave cavity 13, after the container passes through thethrough hole 12 and is inserted into thejack 41, theconcave cavity 13 is used for accommodating a cover body of the container, aheating cover 5 for sealing theconcave cavity 13 is rotatably connected in theconcave cavity 13, and the lower surface of theheating cover 5 is attached with an electric heating sheet which is electrically connected with thecircuit board assembly 2; through the arrangement of the heating cover and the electric heating sheet, after the electric heating sheet is electrified to generate heat, the electric heating sheet can heat the cover body of the container positioned in the concave cavity, so that condensed water formed on the cover body of the container after the nucleic acid sample in the container is evaporated can be avoided, and the nucleic acid sample can be prevented from being subjected to non-specific amplification due to the reduction of the liquid amount to cause false positive; in addition, when the temperature control circuit works, the temperature of the electric heating sheet is between 75 ℃ and 80 ℃, the temperature control of the electric heating sheet is realized by electrifying the electric heating sheet at intervals, namely the electric heating sheet is powered off after being electrified for a period of time, the electric heating sheet is powered on after being powered off for a period of time, the power on-off time of the electric heating sheet is set in a control module in the circuit board assembly according to theoretical calculation, and the temperature control of the electric heating sheet does not need to be too accurate, so that a temperature sensor does not need to be used.

Apartition plate 14 is arranged in theshell 1, and thepartition plate 14 is used for separating thecircuit board assembly 2 from theelectric heating block 4; through the arrangement of the partition plate, the partition plate can realize the isolation of the circuit board assembly and the electric heating block, so that the heat generated by the electric heating block can be effectively prevented from being transferred to the circuit board assembly, and the influence on the normal work of the circuit board assembly is avoided; in addition, the storage battery and the electric heating block are also separated by a partition plate, namely the storage battery is positioned on one side of the circuit board assembly; in addition, through the setting of baffle, can effectively avoid the scattering and disappearing of the heat of heating the piece.

Adisplay screen 22 is installed on thecircuit board assembly 2, adisplay window 15 is arranged at the upper end of theshell 1, and thedisplay window 15 is arranged corresponding to thedisplay screen 22; through the arrangement of the display screen, the display screen can display the temperature value of the electric heating block, the residual heating time of the nucleic acid sample in the container and other information, namely, a user can intuitively know the key data information of the invention.

Anindicator lamp group 23 is installed on thecircuit board assembly 2, a lighttransmission hole group 16 is arranged at the upper end of theshell 1, and each light transmission hole in the lighttransmission hole group 16 is respectively arranged corresponding to one indicator lamp in theindicator lamp group 23; through the arrangement of the indicator lamp group, one indicator lamp in the indicator lamp group is used as a charging indicator lamp, and the other indicator lamps in the indicator lamp group are used as running indicator lamps, so that a user can judge the charging condition and the running condition of the intelligent charging lamp by observing the on-off or luminous color of the indicator lamp group.

A loudspeaker 6 is fixed on the inner wall of theshell 1, a plurality ofsound outlet holes 17 are formed in theshell 1 at the position of the loudspeaker 6, and the loudspeaker 6 is electrically connected with thecircuit board assembly 2; through the arrangement of the horn, after the nucleic acid sample in the container is heated, the circuit board assembly can control the horn to sound or send out voice prompt information to inform a user that the nucleic acid sample is heated, so that convenience can be brought to the user.

Acharging socket 24 is installed on thecircuit board assembly 2, acharging socket 18 is arranged on theshell 1, and thecharging socket 18 and thecharging socket 24 are arranged correspondingly; apower switch 7 is fixed on the side wall of theshell 1, and thepower switch 7 is electrically connected with thecircuit board assembly 2; through the arrangement of the charging socket, after the charging socket is connected with the power adapter, the power adapter can charge the storage battery in the invention; the power switch is arranged, and the power switch can be operated to conveniently control the on or off of the invention.

When the nucleic acid sample heating instrument inembodiment 1 is used, a container storing a nucleic acid sample is firstly inserted into the insertion hole, then the heating cover is covered on the shell to enable the heating cover to close the cavity, then the button group is triggered by operating the button group to adjust parameters such as time, temperature and the like of heating the nucleic acid sample in the container by the nucleic acid sample heating instrument, and finally the button group is triggered by operating the button group to switch on the power supply of the electric heating block and the electric heating sheet; in addition, in the process of heating the nucleic acid sample, the temperature of the electric heating block is controlled to be 65 ℃ under the action of the circuit board assembly and the temperature sensor inside the electric heating block, and the heating time of the nucleic acid sample is controlled to be 50 minutes; after the nucleic acid sample in the container is heated by the nucleic acid sample heating instrument, the container is taken out of the nucleic acid sample heating instrument, and whether the nucleic acid sample is negative or positive is judged by observing the color of the nucleic acid sample by naked eyes.

Example 2

As shown in fig. 6 to 10, in the present embodiment, the difference fromembodiment 1 is that: afirst lamp plate 8 is arranged in theshell 1 below theelectric heating block 4, lightprojecting lamp beads 81 which are vertically and correspondingly arranged with eachjack 41 are arranged on thefirst lamp plate 8, acamera module 9 is fixed on the inner wall of theshell 1, anopening 42 is arranged at one side of eachjack 41, eachopening 42 faces one side of thecamera module 9, and thefirst lamp plate 8 and thecamera module 9 are electrically connected with thecircuit board assembly 2; through the setting of first lamp plate, after the electric heat piece is accomplished the heating of the nucleic acid sample in the container, every projection lamp pearl that is located on first lamp plate all can be lighted, the projection lamp pearl is lighted the back, every projection lamp pearl can light the container on the corresponding position respectively, simultaneously under the image recognition of camera module, circuit board assembly can judge the positive and negative condition of every nucleic acid sample according to the image data that camera module obtained, and show the testing result on the display screen.

Asliding groove 19 is formed in theshell 1 at the position of each end of thefirst lamp panel 8, two ends of thefirst lamp panel 8 are respectively connected with onesliding groove 19 in a sliding mode, and thefirst lamp panel 8 is used for adjusting the front and back positions of the lightprojecting lamp beads 81 relative to thejacks 41 after sliding along thesliding grooves 19; at least one screw penetrates through thefirst lamp panel 8, the screw is in threaded connection with thefirst lamp panel 8, the end part of the screw is tightly abutted to theshell 1, and thefirst lamp panel 8 and theshell 1 are locked through the screw; after adopting this kind of structure, when assembling first lamp plate for first lamp plate slides along the spout and can adjust the front and back position of light projector lamp pearl for the jack, so, can with the position control of first lamp plate to suitable position, after the position control of first lamp plate is accomplished, screws up the screw and can make first lamp plate and casing locking.

Asecond lamp panel 10 is fixed in theshell 1, thesecond lamp panel 10 is provided with indicatinglamp beads 101 with the same number as thejacks 41, theshell 1 is provided with indicatinglamp holes 111 corresponding to the indicatinglamp beads 101 one by one, and thesecond lamp panel 10 is electrically connected with thecircuit board assembly 2; through the setting of second lamp plate, and the quantity that is located the instruction lamp pearl on the second lamp plate is the same with the quantity of jack, when circuit board assembly passes through the camera module and judges certain nucleic acid sample for positive, the instruction lamp pearl that corresponds with this nucleic acid sample can send ruddiness, when circuit board assembly passes through the camera module and judges certain nucleic acid sample for negative, the instruction lamp pearl that corresponds with this nucleic acid sample can send the green glow, so, the user can conveniently judge the negative and positive condition of every nucleic acid sample through the luminous colour of instruction lamp pearl.

When the nucleic acid sample heating instrument inembodiment 2 is used, a container storing a nucleic acid sample is firstly inserted into the insertion hole, then the heating cover is covered on the shell to enable the heating cover to close the cavity, then the button group is triggered by operating the button group to adjust parameters such as time, temperature and the like for heating the nucleic acid sample in the container by the nucleic acid sample heating instrument, and finally the button group is triggered by operating the button group to switch on the power supply of the electric heating block and the electric heating sheet; in addition, in the process of heating the nucleic acid sample, the temperature of the electric heating block is controlled to be 65 ℃ under the action of the circuit board assembly and the temperature sensor inside the electric heating block, and the heating time of the nucleic acid sample is controlled to be 50 minutes; after the nucleic acid sample in the container is heated by the nucleic acid sample heating instrument, the nucleic acid sample heating instrument can automatically judge the positive and negative conditions of the nucleic acid sample through the action of the first lamp panel, the camera module and the circuit board assembly, and conveniently indicate the positive and negative conditions of each nucleic acid sample through the luminous color of the indicating lamp beads.

The above description is only an embodiment of the present invention, and is not intended to limit the present invention. Various modifications and alterations to this invention will become apparent to those skilled in the art. Any modification, equivalent replacement, improvement or the like made within the spirit and principle of the present invention should be included in the scope of the claims of the present invention.

Claims (10)

1. A nucleic acid sample heating instrument, characterized in that: the temperature control circuit board comprises a shell (1), wherein a circuit board assembly (2), a storage battery (3) and an electric heating block (4) are fixed inside the shell (1), a temperature sensor is embedded inside the electric heating block (4), the storage battery (3), the electric heating block (4) and the temperature sensor are electrically connected with the circuit board assembly (2), and a button group (11) used for triggering a button group (21) positioned on the circuit board assembly (2) is installed on the shell (1); the electric heating block (4) is internally provided with a plurality of jacks (41) for inserting containers storing nucleic acid samples, the upper end of the shell (1) is provided with through holes (12) which correspond to the jacks (41) one by one, and each through hole (12) is used for allowing a container to pass through so that the container can be inserted into the jacks (41) at corresponding positions conveniently.

2. The nucleic acid sample heating instrument according to claim 1, wherein a cavity (13) is formed in the upper end of the casing (1), after the container passes through the through hole (12) and is inserted into the insertion hole (41), the cavity (13) is used for accommodating a cover body of the container, a heating cover (5) for closing the cavity (13) is rotatably connected in the cavity (13), and an electric heating sheet is attached to the lower surface of the heating cover (5) and electrically connected with the circuit board assembly (2).

3. The nucleic acid sample heating instrument according to claim 1, wherein a partition plate (14) is installed inside the case (1), and the partition plate (14) is used for separating the circuit board assembly (2) and the electric heating block (4).

4. The nucleic acid sample heating instrument according to claim 1, wherein a display screen (22) is mounted on the circuit board assembly (2), a display window (15) is disposed at the upper end of the housing (1), and the display window (15) is disposed corresponding to the display screen (22).

5. The instrument of claim 1, wherein the circuit board assembly (2) is provided with a set of indicator lights (23), the housing (1) is provided at an upper end thereof with a set of light-transmitting holes (16), and each of the light-transmitting holes (16) is provided corresponding to one of the indicator lights of the set of indicator lights (23).

6. The nucleic acid sample heating instrument according to claim 1, wherein a speaker (6) is fixed on the inner wall of the housing (1), a plurality of sound holes (17) are arranged on the housing (1) at the position of the speaker (6), and the speaker (6) is electrically connected with the circuit board assembly (2).

7. The nucleic acid sample heating instrument according to claim 1, wherein a charging socket (24) is installed on the circuit board assembly (2), a charging socket (18) is provided on the housing (1), and the charging socket (18) is provided corresponding to the charging socket (24); and a power switch (7) is fixed on the side wall of the shell (1), and the power switch (7) is electrically connected with the circuit board assembly (2).

8. The nucleic acid sample heating instrument according to claim 1, wherein a first lamp panel (8) is arranged in a shell (1) below the electric heating block (4), light projecting lamp beads (81) which are vertically arranged in one-to-one correspondence to each jack (41) are installed on the first lamp panel (8), a camera module (9) is fixed on the inner wall of the shell (1), an opening (42) is arranged on one side of each jack (41), each opening (42) faces one side of the camera module (9), and the first lamp panel (8) and the camera module (9) are electrically connected with a circuit board assembly (2).

9. The nucleic acid sample heating instrument according to claim 8, wherein a sliding groove (19) is formed in the shell (1) at each end of the first lamp panel (8), two ends of the first lamp panel (8) are respectively connected with one sliding groove (19) in a sliding manner, and the first lamp panel (8) is used for adjusting the front and back positions of the light projecting lamp bead (81) relative to the jack (41) after sliding along the sliding groove (19); wear to be equipped with at least one screw in first lamp plate (8), screw and first lamp plate (8) threaded connection, the tip and casing (1) of screw support tightly, first lamp plate (8) pass through screw locking with casing (1).

10. The nucleic acid sample heating instrument according to claim 8, wherein a second lamp panel (10) is fixed in the casing (1), the second lamp panel (10) is provided with indicating lamp beads (101) with the same number as the number of the jacks (41), the casing (1) is provided with indicating lamp holes (111) corresponding to each indicating lamp bead (101), and the second lamp panel (10) is electrically connected with the circuit board assembly (2).

Images