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CN113827337A - Plasma scalpel and plasma surgical system thereof - Google Patents

Plasma scalpel and plasma surgical system thereof
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Publication number
CN113827337A
CN113827337ACN202111258097.2ACN202111258097ACN113827337ACN 113827337 ACN113827337 ACN 113827337ACN 202111258097 ACN202111258097 ACN 202111258097ACN 113827337 ACN113827337 ACN 113827337A
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grating
plasma
inner electrode
module
fiber
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CN113827337B (en
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梁应平
唐元章
林嘉
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Nanchang Jiayan Technology Co ltd
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Nanchang Jiayan Technology Co ltd
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Abstract

The invention discloses a plasma scalpel and a plasma scalpel system thereof, wherein the plasma scalpel is of a multi-layer concentric structure and comprises an outer electrode, an insulating layer, an inner electrode, a reflecting layer and a grating optical fiber, the plasma scalpel is of a multi-layer concentric rod-shaped structure, a grating used for temperature induction is etched on the grating optical fiber, the outer wall of the grating optical fiber is coated with a tubular inner electrode, the reflecting layer with low refractive index is arranged between the grating optical fiber and the inner electrode, the outer wall of the inner electrode is provided with the outer electrode, the insulating layer is arranged between the inner electrode and the outer electrode, the distance from the axis of the fiber grating to the end face of the inner electrode is less than 5mm, and the length of the insulating layer extending out of the end part of the inner electrode is 2-5 mm. Compared with a monopolar plasma knife, the bipolar plasma knife has a more obvious constraint effect on an electric field, can concentrate plasma in a smaller area, avoids surgical injury as much as possible, is favorable for enhancing the success rate of surgery and reducing the pain of a patient, and is more suitable for fine operation.

Description

Plasma scalpel and plasma surgical system thereof
Technical Field
The invention relates to the technical field of plasma scalpels and plasma surgical systems thereof, in particular to a plasma scalpels and a plasma surgical system thereof.
Background
The ion scalpel and the plasma surgical system thereof on the market are generally not practical enough at present, most of the plasma scalpels lack temperature measurement and impedance measurement, the temperature of an affected area is too high in the plasma surgical process and can cause extra damage to a patient, the central temperature of medical high-temperature plasma can reach 150 degrees, the temperature of low-temperature plasma can also reach 70 degrees at most, and the range of a temperature-raising area of the plasma minimally invasive surgery must be strictly controlled; no matter which kind of plasma knife, human tissue needs to participate in the radio frequency current loop, so the impedance of human body or local area can also influence the magnitude of radio frequency current, and the impedance of human tissue can influence the magnitude of plasma current, which is more serious to the influence of operation. On one hand, the size of the plasma discharge electric quantity needs to be matched with the impedance of human tissues at the operation part, the achievement of the expected effect is influenced by over-large or over-small current, and meanwhile, unnecessary injury is possibly caused to a patient; on the other hand, the plasma operation process is only the last knife discharge, the plasma knife needs to pass through a plurality of navigation and positioning processes when entering the human body and accurately reaching the operation area, the consequences are very serious once the positioning is wrong, the positioning method of the plasma knife is intuitive and effective, the patient is slightly stimulated by applying small current, when the motor nerve of the human body is stimulated, the muscle tissue innervated by the nerve can generate motor reflex, when the sensory nerve is stimulated, the electrical change of nerve fiber can be transmitted into the brain to be sensed by the human body, the positioning process can not generate any damage to the human tissue, the amount of current generated cannot be excessive, and the impedance of the body tissue must be taken into account, the real-time impedance measurement of the plasma discharge loop is an important function of the plasma minimally invasive surgery equipment.
In addition, with the technological progress, the smaller the opening on the body surface of a patient, the better the minimally invasive surgery is pursued, so the thinner the minimally invasive plasma scalpel is, the better the minimally invasive plasma scalpel is, the diameter of the minimally invasive plasma scalpel is generally not more than 1mm, the temperature peak value in the surgery occurs at the knife tip, meanwhile, in order to determine the diffusion range of the temperature, the temperature measurement needs to be carried out at the point millimeter away from the knife tip, the temperature measurement and the impedance measurement are lacked, which causes the limited use range of the plasma scalpel, the surgery injury is easy to cause, and much trouble is caused to patients and doctors, therefore, the technical prospect in the aspect is wide, and the space for deep excavation is provided.
Disclosure of Invention
In view of the defects of the prior art, the invention aims to provide a plasma scalpel and a plasma surgical system thereof, and aims to solve the problem that other existing devices in the market are easy to cause additional damage due to the fact that temperature measurement and impedance measurement do not exist.
In order to realize the purpose, the invention adopts the following technical scheme:
a plasma scalpel is of a multi-layer concentric structure and comprises anouter electrode 1, aninsulating layer 2, aninner electrode 3 and a reflectinglayer 4, the gratingoptical fiber 5 is etched with a grating for temperature sensing, the outer wall of the gratingoptical fiber 5 is coated with a tubularinner electrode 3, the wall thickness range of theinner electrode 3 is 0.25-0.5mm, a reflectinglayer 4 with low refractive index is arranged between the gratingoptical fiber 5 and theinner electrode 3, the outer wall of theinner electrode 3 is provided with anouter electrode 1, the wall thickness of theouter electrode 1 is less than 1mm, aninsulating layer 2 is arranged between theinner electrode 3 and theouter electrode 1, the distance from the axis of theoptical fiber grating 5 to the end face of theinner electrode 3 is less than 5mm, the length of theinsulating layer 2 extending out of the end part of theinner electrode 3 is 2-5mm, and the length of theouter electrode 1 extending out of the end part of theinsulating layer 2 is 2-5 mm; the end part of theinner electrode 3 is provided with a spherical head for preventing human tissue from being damaged.
Preferably, thegrating fiber 5 comprises a plurality of gratings, the length of each grating is less than 3mm, the distance from the axis of each grating to the end face of theinner electrode 3 is less than 5mm, and the distance between the center positions of two adjacent temperature measurement gratings is 4-8 mm.
Preferably, thegrating fiber 5 comprises 2-5temperature measurement fibers 6, wherein the distance from the axis of the temperature measurement grating of the firsttemperature measurement fiber 6 to the end face of theinner electrode 3 is less than 5mm, and the distance from the axis of the temperature measurement grating of each of the resttemperature measurement fibers 6 to the axis of the temperature measurement grating of the firsttemperature measurement fiber 6 is 4-8 mm.
Furthermore, the grating optical fiber temperature sensor is a new micro temperature measurement technology, the main body of the sensor is a single-core optical fiber, a section of grating is etched at a certain position of the optical fiber through a laser technology, when light passes through the grating, light with the wavelength matched with the gap distance of the grating can be reflected under the action of diffraction, when the temperature at the position of the grating is changed, the central frequency of reflected light can be shifted due to the photo-thermal effect, by utilizing the phenomenon, a light source with composite frequency is irradiated into one end of the gratingoptical fiber 5, the central frequency of the reflected light is measured, the temperature at the position of the grating can be correspondingly obtained, under the support of the existing precision measurement technology, a plurality of gratings can be simultaneously etched on the optical fiber, the multipoint temperature can be simultaneously obtained on the same optical fiber through measuring the reflected wavelength at different times, the size of the grating optical fiber temperature sensor is small, the diameter of the single optical fiber is only 0.125mm, the diameter of the external reflectinglayer 4 is not more than 0.25mm, no metal material is used, electricity is not needed, the anti-corrosion and anti-electromagnetic interference capabilities are excellent, and the multipoint temperature measurement can be carried out on the single optical fiber, which are not possessed by the traditional thermocouple, so that the thermocouple is very suitable for being used in the plasma minimally invasive surgery.
The technical scheme also provides a plasma surgery system which is characterized by comprising a power supply module, a main control module, a radio frequency generation module, a low-frequency alternating current generation module, a grating optical fiber mediation module, an impedance measurement circuit, a change-over switch, a control and display panel and the plasma scalpel as claimed in any one ofclaims 1 to 4, wherein the power supply module adopts an AMS1117 chip to stably output 5V voltage, a power supply end is connected with 200-minus-V alternating current and is subjected to voltage reduction through a transformer T1, a rectifier bridge D1 and capacitors C3 and C4 are connected with the AMS1117 chip after alternating current is changed into direct current, and 5V driving voltage is stably output.
As a preferred scheme, the radio frequency generation module is used for generating a 50KHz-500KHz radio frequency power supply required by low-temperature plasma, the low-frequency alternating current generation module is used for generating a 0.1-100Hz low-frequency alternating current power supply required by nerve electrical stimulation, the change-over switch can select one of the two electric signals and send the selected electric signal to the plasma knife, the control panel can adjust power supply parameters, the impedance measurement circuit simultaneously carries out real-time measurement on information such as power supply voltage and current and the like, the tissue impedance of a plasma discharge loop is calculated and displayed in real time, the grating optical fiber modulation module is used for driving a grating optical fiber temperature sensor, the temperature information of an operation area is simultaneously displayed on the panel in real time, and all the modules work cooperatively.
Preferably,pins 1, 24, 36 and 48 of the mainchip STM32F103C8T 6U 1 of the main control module are connected together to be connected with 5V voltage,pins 5 and 6 are connected with the clock circuit, pins 8, 23, 35 and 47 are connected together to be grounded, pins 9 are connected with 5V voltage, pins 10 are connected with Ln1 of the LCD, pins 11 are connected with Ln2 of the LCD, pins 12 are connected with Ln3 of the LCD, pins 13 are connected with Ln4 of the LCD, pins 14 are connected with Ln5 of the LCD, pins 15 are connected with a KEY1, a resistor R2 is grounded, pins 16 are connected with a KEY2, a resistor R3 is grounded, pins 17 are connected with a KEY3, a resistor R4 is grounded, pins 18 TX are connected with a KEY4, a resistor R5 is grounded, pins 28 are connected with RX interface of the optical fiber grating optical fiber waveform module P3, pins 29 are connected with RX interface of the optical fiber grating module P3, the first pin of the 39 pin is grounded through a capacitor C7, the second pin is grounded through a resistor R9, the third pin is connected with a plasma knife output terminal OUT2 through a resistor R8, the first pin of the 40 pin is grounded through a capacitor C6, the second pin is grounded through a resistor R7, the third pin is connected with a plasma knife output terminal OUT1 through a resistor R6, the 41 pin is connected with a D interface of the radio frequency module P2, the 42 pin is connected with an I interface of the radio frequency module P2, the 43 pin is connected with a P interface of the radio frequency module P2, the 44 pin is connected with a DIR interface of the low frequency alternating current module P1, the 45 pin is connected with a PWM interface of the low frequency alternating current module P1, and the 46 pin is connected with an EN interface of the low frequency alternating current module P1.
As a preferred scheme, the radio frequency generation module, P, I, D interface connects the main control chip STM32F103C8T6, carry on the information exchange, the carry-out terminal passes the diverter switch and changes the connection plasma knife; and the low-frequency alternating current generation module EN, PWM and DIR interfaces are connected with a main control chip STM32F103C8T6 for information exchange, and the output end is connected with a plasma knife through the conversion of a selector switch.
As the preferred scheme, the grating fiber-optic mediation module mainly comprises a grating fiber-optic waveform sampling module and a grating fiber-optic probe, wherein 1 pin of the grating fiber-optic waveform sampling module P3 is connected with a 5V power supply, 2 and 3 pins are connected with a main control chip STM32F103C8T6, 4 pins are grounded, 5 pins are connected with 4 pins of the grating fiber-optic probe J2, 6 pins are connected with 3 pins of the grating fiber-optic probe J2, 7 pins are connected with 2 pins of the grating fiber-optic probe J2, and 8 pins are connected with 1 pin of the grating fiber-optic probe J2.
As a preferred scheme, one end of the impedance measurement circuit is connected with a main control chip STM32F103C8T6, and the other end of the impedance measurement circuit is connected with a plasma knife; and one end of the key module is connected with the main control chip STM32F103C8T6, and the other end of the key module is grounded.
As the preferred scheme, the display module mainly comprises an LCD drive chip U2 and an LCD display screen J1, wherein one end of the LCD drive chip U2 is connected with a main control chip STM32F103C8T6, and the other end is connected with the LCD display screen J1 through an LCD bus.
Has the advantages that:
the invention has the beneficial effects that: the plasma knife is driven by a high-voltage radio-frequency power supply, and plasma is released at the knife tip through arc discharge. The plasma current of the bipolar or multistage plasma knife is emitted from one stage and then flows into the other stage, and the discharge arc between the two stages is used for carrying out operation on human tissues. The resulting rf current has the highest charge density and amperage in the peripheral region immediately adjacent the tip and thus produces a cutting or fusing action. Compared with a monopolar plasma knife, the bipolar plasma knife has a more obvious constraint effect on an electric field, can concentrate plasma in a smaller area, avoids surgical injury as much as possible, is favorable for enhancing the success rate of surgery and reducing the pain of a patient, and is more suitable for fine operation.
Drawings
FIG. 1 is a power module;
FIG. 2 is a main control module;
FIG. 3 is a diagram of a radio frequency generation module and a low frequency AC generation module;
FIG. 4 is a grating fiber mediation module;
FIG. 5 is an impedance measurement circuit;
FIG. 6 is a key module;
FIG. 7 is a display module;
FIG. 8 is a block diagram of a plasma surgical system;
FIG. 9 is a sectional view of a single-core single-grating tubular inner electrode plasma cutter;
FIG. 10 is a cross-sectional view of a single core plasma knife configuration;
FIG. 11 is a cross-sectional view of a single-core multi-grating ball-end inner electrode plasma cutter structure;
FIG. 12 is a cross-sectional view of a multi-core plasma knife configuration.
Detailed Description
In order to facilitate an understanding of the invention, the invention is described in more detail below with reference to the accompanying drawings and specific examples. The preferred embodiments of the present invention are shown in the drawings, but the present invention may be embodied in many different forms and should not be construed as being limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for descriptive purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.
As shown in fig. 9 to 12, a plasma scalpel, which is a multi-layered concentric structure, includes anouter electrode 1, aninsulating layer 2, aninner electrode 3, areflective layer 4, the gratingoptical fiber 5 is etched with a grating for temperature sensing, the outer wall of the gratingoptical fiber 5 is coated with a tubularinner electrode 3, the wall thickness range of theinner electrode 3 is 0.25-0.5mm, a reflectinglayer 4 with low refractive index is arranged between the gratingoptical fiber 5 and theinner electrode 3, the outer wall of theinner electrode 3 is provided with anouter electrode 1, the wall thickness of theouter electrode 1 is less than 1mm, aninsulating layer 2 is arranged between theinner electrode 3 and theouter electrode 1, the distance from the axis of theoptical fiber grating 5 to the end face of theinner electrode 3 is less than 5mm, the length of theinsulating layer 2 extending out of the end part of theinner electrode 3 is 2-5mm, and the length of theouter electrode 1 extending out of the end part of theinsulating layer 2 is 2-5 mm; the end part of theinner electrode 3 is provided with a spherical head for preventing human tissue from being damaged.
In the single-core embodiment, the gratingoptical fiber 5 comprises a plurality of gratings, the length of each grating is less than 3mm, the distance from the axis of each grating to the end face of theinner electrode 3 is less than 5mm, and the distance between the center positions of two adjacent temperature measurement gratings is 4-8 mm.
In the multi-core embodiment, thegrating fiber 5 includes 2-5 temperature measuringfibers 6, wherein the distance from the axis of the temperature measuring grating of the firsttemperature measuring fiber 6 to the end surface of theinner electrode 3 is less than 5mm, and the distance from the axis of the temperature measuring grating of each of the resttemperature measuring fibers 6 to the axis of the temperature measuring grating of the firsttemperature measuring fiber 6 is 4-8 mm.
Furthermore, the grating optical fiber temperature sensor is a new micro temperature measurement technology, the main body of the sensor is a single-core optical fiber, a section of grating is etched at a certain position of the optical fiber through a laser technology, when light passes through the grating, light with the wavelength matched with the gap distance of the grating can be reflected under the action of diffraction, when the temperature at the position of the grating is changed, the central frequency of reflected light can be shifted due to the photo-thermal effect, by utilizing the phenomenon, a light source with composite frequency is irradiated into one end of the gratingoptical fiber 5, the central frequency of the reflected light is measured, the temperature at the position of the grating can be correspondingly obtained, under the support of the existing precision measurement technology, a plurality of gratings can be simultaneously etched on the optical fiber, the multipoint temperature can be simultaneously obtained on the same optical fiber through measuring the reflected wavelength at different times, the size of the grating optical fiber temperature sensor is small, the diameter of the single optical fiber is only 0.125mm, the diameter of the external reflectinglayer 4 is not more than 0.25mm, no metal material is used, electricity is not needed, the anti-corrosion and anti-electromagnetic interference capabilities are excellent, and the multipoint temperature measurement can be carried out on the single optical fiber, which are not possessed by the traditional thermocouple, so that the thermocouple is very suitable for being used in the plasma minimally invasive surgery.
The embodiment also comprises a plasma surgery system, which comprises a power supply module, a main control module, a radio frequency generation module, a low-frequency alternating current generation module, a grating optical fiber mediation module, an impedance measurement circuit, a change-over switch, a control and display panel and a plasma scalpel, wherein the power supply module supplies power to the whole system, the radio frequency generation module is used for generating a 50KHz-500KHz radio frequency power supply required by low-temperature plasma, the low-frequency alternating current generation module is used for generating a 0.1-100Hz low-frequency alternating current power supply required by nerve electrical stimulation, the change-over switch can select one of the two electric signals to be sent to the plasma scalpel, the control panel can adjust power supply parameters, the impedance measurement circuit simultaneously carries out real-time measurement on information such as power supply voltage and current, the tissue impedance of a plasma discharge loop is calculated and displayed in real time, the grating optical fiber mediation module is used for driving a grating optical fiber temperature sensor, the temperature information of the operation area is displayed on the panel in real time, and the whole system works cooperatively under the control of the main control module.
As shown in fig. 1, the power module adopts the AMS1117 chip to stably output 5V voltage, the power supply terminal is connected to 200-250V ac power, the voltage is reduced by the transformer T1, the rectifier bridge D1 and the capacitors C3 and C4 are connected to the AMS1117 chip in a dc-to-dc manner, and 5V driving voltage is stably output.
As shown in fig. 2,pins 1, 24, 36 and 48 of the mainchip STM32F103C8T 6U 1 of the main control module are connected together to a 5V voltage,pins 5, 6 are connected to a clock circuit, pins 8, 23, 35 and 47 are connected together to ground, pins 9 are connected to a 5V voltage, pins 10 are connected to Ln1 of the LCD, pins 11 are connected to Ln2 of the LCD, pins 12 are connected to Ln3 of the LCD, pins 13 are connected to Ln4 of the LCD, pins 14 are connected to Ln5 of the LCD, pins 15 are connected to ground through a KEY1, pins R2 and 16 are connected to ground through a KEY2, pins R3 are connected to ground, pins 17 are connected to ground through a KEY3, pins R4 are connected to ground, pins 18TX 4 are connected to aKEY 5, pins 28 are connected to an RX interface of the optical fiber module P3, pins 29 are connected to an optical fiber module P interface 38, the first pin of the 39 pin is grounded through a capacitor C7, the second pin is grounded through a resistor R9, the third pin is connected with a plasma knife output terminal OUT2 through a resistor R8, the first pin of the 40 pin is grounded through a capacitor C6, the second pin is grounded through a resistor R7, the third pin is connected with a plasma knife output terminal OUT1 through a resistor R6, the 41 pin is connected with a D interface of the radio frequency module P2, the 42 pin is connected with an I interface of the radio frequency module P2, the 43 pin is connected with a P interface of the radio frequency module P2, the 44 pin is connected with a DIR interface of the low frequency alternating current module P1, the 45 pin is connected with a PWM interface of the low frequency alternating current module P1, and the 46 pin is connected with an EN interface of the low frequency alternating current module P1.
As shown in fig. 3, the radio frequency generation module, P, I, D interfaces are connected to a main control chip STM32F103C8T6 for information exchange, and the output terminal is switched to connect the plasma knife through a switch; and the low-frequency alternating current generation module EN, PWM and DIR interfaces are connected with a main control chip STM32F103C8T6 for information exchange, and the output end is connected with a plasma knife through the conversion of a selector switch.
As shown in fig. 4, the grating fiber mediation module mainly comprises a grating fiber waveform sampling module and a grating fiber probe, wherein 1 pin of the grating fiber waveform sampling module P3 is connected with a 5V power supply, 2 and 3 pins are connected with a main control chip STM32F103C8T6, 4 pins are grounded, 5 pins are connected with 4 pins of the grating fiber probe J2, 6 pins are connected with 3 pins of the grating fiber probe J2, 7 pins are connected with 2 pins of the grating fiber probe J2, and 8 pins are connected with 1 pin of the grating fiber probe J2.
As shown in fig. 5-6, one end of the impedance measurement circuit is connected with the main control chip STM32F103C8T6, and the other end is connected with the plasma knife; and one end of the key module is connected with the main control chip STM32F103C8T6, and the other end of the key module is grounded.
As shown in fig. 7, the display module mainly comprises an LCD driver chip U2 and an LCD display screen J1, wherein one end of the LCD driver chip U2 is connected to a main control chip STM32F103C8T6, and the other end is connected to the LCD display screen J1 through an LCD bus.
As shown in fig. 8, a plasma surgical system, particularly a minimally invasive cryogenic plasma surgical system, includes: a power module, a main control module, a radio frequency generation module, a low frequency AC generation module, a grating fiber mediation module, an impedance measurement circuit, a change-over switch, a control and display panel, wherein the power module supplies power to the whole system, the radio frequency generation module is used for generating a 50KHz-500KHz radio frequency power required by low temperature plasma, the low frequency AC generation module is used for generating a 0.1-100Hz low frequency AC power required by nerve electrical stimulation, the change-over switch can select one of the two electric signals to be sent to a plasma knife, the control panel can adjust power supply parameters, the impedance measurement circuit simultaneously carries out real-time measurement on information such as power supply voltage and current, the tissue impedance of a plasma discharge loop is calculated and displayed in real time, the grating fiber mediation module is used for driving a grating fiber temperature sensor, and the temperature information of an operation area is simultaneously displayed on the panel in real time, the whole system works cooperatively under the control of the main control module.

Claims (5)

1. The utility model provides a plasma scalpel, its characterized in that, plasma scalpel is multilayer concentric structure, including outer electrode (1), insulating layer (2), inner electrode (3), reflection stratum (4), and grating optic fibre (5), the plasma scalpel multilayer is concentric shaft-like structure, grating optic fibre (5) diameter scope is 0.1-0.15mm, the sculpture has the grating that is used for temperature-sensing on grating optic fibre (5), grating optic fibre (5) outer wall cladding has cast inner electrode (3), inner electrode (3) wall thickness scope 0.25-0.5mm, grating optic fibre (5) with be equipped with reflection stratum (4) of low refractive index between inner electrode (3), inner electrode (3) outer wall is equipped with outer electrode (1), outer electrode (1) wall thickness is less than 1mm, inner electrode (3) with be equipped with insulating layer (2) between outer electrode (1), the distance from the axis of the fiber grating (5) to the end face of the inner electrode (3) is less than 5mm, the length of the part of the inner electrode (3) extending out of the insulating layer (2) is 2-5mm, and the length of the part of the insulating layer (2) extending out of the outer electrode (1) is 2-5 mm; the end part of the inner electrode (3) is provided with a spherical head for preventing human tissue from being damaged.
5. The plasma surgical system of claim 4, wherein the RF generating module is configured to generate a RF power of 50KHz to 500KHz required for generating low temperature plasma, the low frequency AC generating module is configured to generate a low frequency AC power of 0.1 Hz to 100Hz required for electrical nerve stimulation, the switch is configured to select one of the two electrical signals to be transmitted to the plasma knife, the control panel is configured to adjust power supply parameters, the impedance measuring circuit is configured to measure power supply voltage and current simultaneously in real time, calculate and display tissue impedance of the plasma discharge circuit in real time, the fiber grating regulating module is configured to drive the fiber grating temperature sensor, the temperature information of the surgical field is also displayed simultaneously on the panel in real time, and the modules work cooperatively.
CN202111258097.2A2021-10-272021-10-27Plasma surgical knife and plasma surgical system thereofExpired - Fee RelatedCN113827337B (en)

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