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CN113441851A - Method for opening artificial blood vessel - Google Patents

Method for opening artificial blood vessel
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Publication number
CN113441851A
CN113441851ACN202010218709.4ACN202010218709ACN113441851ACN 113441851 ACN113441851 ACN 113441851ACN 202010218709 ACN202010218709 ACN 202010218709ACN 113441851 ACN113441851 ACN 113441851A
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hole
blood vessel
artificial blood
point
connecting hole
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CN202010218709.4A
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CN113441851B (en
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宗雪
马晓曼
姚昊
谷子琦
阙亦云
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Maitong Medical Technology Jiaxing Co ltd
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Maitong Medical Technology Jiaxing Co ltd
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Abstract

The invention relates to a hole opening method of an artificial blood vessel, which comprises the following steps of positioning and cutting a reference hole and a connecting hole, wherein the step of positioning and cutting the reference hole and the connecting hole comprises the following steps: positioning the central point of the reference hole on the surface of the artificial blood vessel main body, and cutting the surface of the artificial blood vessel main body to form the reference hole based on the preset radius of the reference hole by taking the central point of the reference hole as the center of a circle; the artificial blood vessel surface positioning method comprises the following steps that the center point of a connecting hole is positioned on the surface of an artificial blood vessel main body in the same circumferential direction and the same axial direction of the center point of a reference hole, the center point of the connecting hole is used as the center of a circle, the preset radius of the connecting hole is used for positioning the surface of the artificial blood vessel main body at the opening starting point of the connecting hole, and the connecting hole is formed in a cutting mode. The position of the hole formed in the embodiment on the artificial blood vessel is consistent with the preset position, and the hole position is accurate; the shape of the cutting hole is regular, and the overall quality of the artificial blood vessel product is improved.

Description

Method for opening artificial blood vessel
Technical Field
The invention relates to the technical field of artificial blood vessel repair, in particular to a hole opening method of an artificial blood vessel.
Background
The thoracic aorta disease is a very dangerous disease in clinic, the death rate of the disease course is high, and the operation-related complications are many, which always troubles the field of the cardiac vascular surgery.
With the application of new technology and new artificial blood vessel materials, the branch type artificial blood vessel products are widely applied in the treatment of thoracic aorta diseases, for example, the aorta lesion part can be directly replaced by the branch type artificial blood vessel, so the performance of the branch type artificial blood vessel is a key factor determining the treatment effect, and the core technology determining the performance of the branch type artificial blood vessel is the hole cutting technology of the artificial blood vessel. The artificial blood vessel surface is usually provided with a plurality of connecting holes for suture connection with the butted artificial blood vessel, and the connecting holes are usually distributed on the artificial blood vessel surface along the length direction of the artificial blood vessel and the direction vertical to the length direction, and the whole distribution is usually in a T shape or an L shape. At present, the domestic branched artificial blood vessel products are difficult to achieve higher accuracy due to the limitation of technical conditions, and the following problems are generally existed: firstly, a branch type artificial blood vessel product is used as a hollow cylindrical three-dimensional structure, although the distance between the central points of different holes on the artificial blood vessel and the radius of each hole are preset, because the artificial blood vessel cannot be marked in advance, cutting equipment cannot be accurately positioned to other connecting holes after one connecting hole is formed, and the positions of the connecting holes formed by cutting on the artificial blood vessel are not accurate; in addition, the shape of the formed hole is mostly oval or other shapes with irregular shapes, which can not meet the use requirements.
The two points reduce the overall quality of the artificial blood vessel product, the position of the artificial blood vessel product with inaccurate cut hole in the human body can deviate after the artificial blood vessel product is sewn with the artificial blood vessel in the human body, and further the human body has concurrent symptoms, the treatment effect is difficult to ensure, the use safety is poor, and therefore the clinical use requirement cannot be met.
Disclosure of Invention
Therefore, it is necessary to provide a method for perforating an artificial blood vessel in order to solve the problems that the respective connection holes cannot be accurately positioned and the shapes of the holes are mostly irregular.
An artificial blood vessel tapping method comprising positioning and cutting a reference hole and a connection hole, the positioning and cutting of the reference hole and the connection hole comprising:
positioning the central point of the reference hole on the surface of the artificial blood vessel main body, and cutting the surface of the artificial blood vessel main body to form the reference hole based on the preset radius of the reference hole by taking the central point of the reference hole as the center of a circle;
the artificial blood vessel surface positioning method comprises the following steps that the center point of a connecting hole is positioned on the surface of an artificial blood vessel main body in the same circumferential direction and the same axial direction of the center point of a reference hole, the center point of the connecting hole is used as the center of a circle, the preset radius of the connecting hole is used for positioning the surface of the artificial blood vessel main body at the opening starting point of the connecting hole, and the connecting hole is formed in a cutting mode.
The positioning hole cutting method of the artificial blood vessel has at least the following beneficial technical effects:
the traditional hole opening mode has the problems that the artificial blood vessels cannot be marked in advance, and after one connecting hole is formed, the cutting equipment cannot be accurately positioned to the central point and the initial cutting point of each other connecting hole.
In this embodiment, a connection hole is first selected and formed, a center point of the connection hole to be formed and a hole forming starting point are calculated and positioned using the formed connection hole as a reference, a hole is cut using the hole forming starting point as a starting point, and the connection holes are formed in sequence. The positions of the formed cutting holes on the artificial blood vessel are consistent with the preset positions, and the hole positions are accurate; the shape of the cutting hole is regular and round, thereby improving the overall quality of the artificial blood vessel product.
The artificial blood vessel product with accurate cutting hole can be accurately connected with the artificial blood vessel in the human body, the position in the human body is accurately positioned after the artificial blood vessel product is sutured with the artificial blood vessel in the human body, and the probability of the human body to generate complicating symptoms is reduced, so that the treatment effect and the use safety can be ensured, and the clinical use requirement can be met.
In one embodiment, the step of locating the center point of the connection hole on the surface of the artificial blood vessel body along the same circumference of the center point of the reference hole comprises:
calculating a central angle of the central point of the reference hole and the central point of the connecting hole relative to the axis of the artificial blood vessel body according to a triangle cosine law based on a linear distance between the central point of the reference hole and the central point of the connecting hole and the radius of the artificial blood vessel body;
and calculating the arc length between the central point of the connecting hole and the central point of the reference hole according to an arc length formula based on the central angle and the radius of the artificial blood vessel main body, so as to position the central point of the connecting hole.
In one embodiment, the starting point of the connecting hole and the central point of the reference hole are located in the same circumference direction of the surface of the artificial blood vessel body.
In one embodiment, the step of locating the center point of the connection hole on the surface of the artificial blood vessel body along the same axial direction of the center point of the reference hole comprises:
the center point of the connection hole is positioned based on a straight-line distance in the axial direction between the center point of the reference hole and the center point of the connection hole.
In one embodiment, the starting point of the connecting hole and the central point of the reference hole are positioned on the same axial direction of the surface of the artificial blood vessel body.
In one embodiment, a connection line of a central point of the reference hole and a central point of the connection hole forms a T shape or an L shape and is distributed on the surface of the artificial blood vessel main body.
In one embodiment, the step of cutting the reference hole includes: a central shaft of the perforating equipment is over against the central point of the reference hole, and a cutting head of the perforating equipment is provided with the reference hole according to the preset radius of the reference hole; and
the step of cutting to form the connecting hole comprises the following steps: the central shaft of the perforating equipment is over against the central point of the connecting hole, and the cutting head of the perforating equipment is provided with the connecting hole according to the preset radius of the connecting hole.
In one embodiment, the step of aligning the central axis of the tapping device with the center point of the reference hole comprises: rotating the artificial blood vessel main body to enable the center point of the reference hole to be arranged at the highest position of the surface of the artificial blood vessel main body, enabling the central shaft of the hole opening equipment to vertically and downwards point to the center point of the reference hole, and enabling a cutting head of the hole opening equipment to open a hole according to the preset radius of the reference hole; and
the step that the central shaft of the hole forming equipment is over against the central point of the connecting hole comprises the following steps: and rotating the artificial blood vessel main body to enable the central point of the connecting hole to be arranged at the highest position of the surface of the artificial blood vessel main body, enabling the central shaft of the hole opening equipment to vertically and downwards point to the central point of the connecting hole, and opening the hole by the cutting head of the hole opening equipment according to the preset radius of the connecting hole.
In one embodiment, the cutting speed of the hole forming device is 0-80mm/s, the cutting frequency is 0-100Hz, and the cutting energy is 0-20% of the factory energy of the hole forming device.
An artificial blood vessel obtained by a method for opening a hole in an artificial blood vessel.
Drawings
FIG. 1 is a schematic diagram illustrating the formation of circumferential connecting hole groups in a method for creating a hole in an artificial blood vessel according to an embodiment of the present invention;
fig. 2 is a schematic view illustrating the formation of axial connecting hole groups in the method for forming a hole in an artificial blood vessel according to an embodiment of the present invention.
In the figure, 100, the artificial blood vessel main body; 101. a reference hole; 102. a second connection hole; 103. a third connection hole; 104. and a fourth connecting hole.
Detailed Description
The invention will be further explained with reference to the drawings.
To facilitate an understanding of the invention, the invention will now be described more fully with reference to the accompanying drawings. Preferred embodiments of the present invention are shown in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Those of ordinary skill in the art will recognize that variations and modifications of the various embodiments described herein can be made without departing from the scope of the invention, which is defined by the appended claims. Moreover, descriptions of well-known functions and constructions may be omitted for clarity and conciseness.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present; when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
The invention provides a method for opening an artificial blood vessel. In the schematic view of the vascular prosthesis product shown in fig. 2, there are usually a plurality of reference holes and/or connection holes distributed on the surface of thevascular prosthesis body 100, and the diameter of each reference hole and/or connection hole ranges from 6mm to 12 mm; the hole spacing is the straight line distance between the center points of different reference holes and/or connecting holes, and the range is 0-50 mm. The central points of the reference holes and the connecting holes are connected and arranged to form a T shape or an L shape, namely, the reference holes and the connecting holes are distributed on the surface of the artificial blood vessel along the circumferential direction and the axial direction.
In the present application, first, a connection hole is formed in the circumferential direction on the surface of the artificialblood vessel body 100, see fig. 1. It should be noted that, in fig. 1, for convenience of illustrating the connection holes, the edges of the connection holes are recessed from the surface of the artificialblood vessel body 100 to the inside of the artificial blood vessel, and actually, the edges of the connection holes are located on the surface of the artificialblood vessel body 100.
The method for forming the connecting hole along the circumferential direction comprises the following steps:
step S110: the center point of the reference hole, such as the point A of thereference hole 101, is positioned on the surface of the artificial blood vessel body, and thereference hole 101 is formed by cutting on the surface of the artificial blood vessel body by taking the point A as the center of a circle and by taking the preset radius r1 of the reference hole.
Step S120: and positioning a central point B of the second connectinghole 102 on the surface of the artificial blood vessel main body along the same circumferential direction of the point A of thereference hole 101, positioning an opening starting point of the second connectinghole 102 on the surface of the artificial blood vessel main body based on the preset radius r2 of the second connectinghole 102 by taking the central point B as a circle center, and cutting to form the second connectinghole 102.
Specifically, the starting point of the opening of the second connectinghole 102 may be a point D located on the same circumferential direction of the surface of the artificial blood vessel body as the center point of the reference hole, or may be any point other than the point D determined based on r 2.
In the method, a reference hole is firstly arranged, the central point of a connecting hole is calculated and positioned by taking the central point of the reference hole as a reference, the connecting hole is formed by cutting the surface of the artificial blood vessel main body based on the preset radius of the connecting hole by taking the central point of the connecting hole as the center of a circle, and the connecting holes are sequentially formed according to the method. The positions of the formed connecting holes on the artificial blood vessel are consistent with the preset positions, and the hole positions are accurate; the shape of the connecting hole is regular and round, thereby improving the overall quality of the artificial blood vessel product.
The formed artificial blood vessel product with the accurate reference hole and the accurate connecting hole can be accurately connected with the blood vessel in the human body, the position of the artificial blood vessel in the human body after being sutured with the artificial blood vessel in the human body is accurately positioned, and the probability of the human body to generate the complicating symptoms is reduced, so that the treatment effect and the use safety can be ensured, and the clinical use requirement can be met.
Specifically, the step S120 specifically operates as follows:
step S121: a connecting line between a central point A of thereference hole 101, a central point B of the second connectinghole 102 and a central point O of the artificial blood vesselmain body 100 in the same circumferential direction forms a triangle OAB, the linear distance between the central point A of thereference hole 101 and the central point B of the second connectinghole 102, namely, the chord length AB is known, the AB range is 10-19mm, and the second connectinghole 102 can be ensured to be in a regular circle shape, and the radius R of the artificial blood vesselmain body 100 is determined according to a triangle cosine theorem formula:
cos∠O=(2R2-AB2)/2R2 (1)
calculating to obtain cos & lt O, and converting to obtain the degree of the central angle & lt O of the central point of thereference hole 101 and the central point of the second connectinghole 102 relative to the center of the artificial blood vesselmain body 100 in the same circumferential direction;
step S122: based on the central angle O and the radius R of the artificial blood vesselmain body 100, the arc length L of the connecting line of the central point A of thereference hole 101 and the central point B of the second connectinghole 102 on the surface of the artificial blood vesselmain body 100 is calculated according to the arc length formulaAB
LAB=(3.14*O*R)/180 (2)
Thereby positioning the center point B of thesecond coupling hole 102 on the surface of the artificialblood vessel body 100.
Step S123: the radius r2 of the second connectinghole 102 is known, wherein the radius of the second connectinghole 102 is specifically the radius along the surface of the artificial blood vesselmain body 100, the opening starting point D of the connecting hole is positioned on the surface of the artificial blood vessel main body by taking the center point B as the center based on the radius r2, and the cutting is carried out to form the second connectinghole 102.
In the steps S121 and S122, the central point of the hole to be drilled can be accurately and quickly obtained by combining the cosine theorem formula.
Further, the steps S110 and S120 of cutting a hole on the surface of the artificialblood vessel body 100 specifically include: firstly, the hole forming equipment is over against the central point of the reference hole and/or the connecting hole, and the cutting head of the hole forming equipment is provided with the reference hole and/or the connecting hole according to a preset radius. Specifically, in order to facilitate the actual operation, when the center point is aligned, the artificialblood vessel body 100 may be rotated such that the center point of the reference hole and/or the connection hole is disposed at the highest position of the surface of the artificialblood vessel body 100, the center shaft of the hole forming device is driven such that the center shaft is directed vertically downward toward the center point, and then the cutting head of the hole forming device forms the reference hole and the connection hole according to a preset radius.
After the circumferential connecting holes are opened, the axial connecting holes are continuously opened on the surface of the artificial blood vesselmain body 100. Referring to fig. 2, the step of opening the coupling hole in the axial direction includes:
step S210: selecting thecut reference hole 101 as a reference, and positioning a central point E of a third connectinghole 103 in the connecting holes in the axial direction, wherein the central point E and the central point A of thereference hole 101 are on the same straight line; in this embodiment, thereference hole 101 serves as a reference for both the above opening of the connection hole in the circumferential direction and the connection hole in the axial direction.
Step S220: and positioning the opening starting point G of the third connectinghole 103 on the surface of the artificial blood vessel main body based on the preset radius r3 of the third connectinghole 103 by taking the central point E of the third connectinghole 103 as the center of a circle, and cutting to form the third connectinghole 103.
Wherein, the step S210 specifically operates as follows:
step S211: positioning a center point E of the third connectinghole 103 on the surface of the artificial blood vesselmain body 100 based on a distance AE between the center point E of the third connectinghole 103 and the center point A of thereference hole 101;
step S212: the radius r3 of the third connectinghole 103 positions the starting point G of the opening of the third connectinghole 103 on the surface of the artificial blood vessel with the center point E as the center based on the radius r3, and the third connectinghole 103 is cut and formed.
Specifically, the starting point of the opening of the third connectinghole 103 may be a G point located on the same axial direction of the surface of the artificial blood vessel body as the center point of the reference hole, or may be any point other than the G point determined based on r 3.
In the steps S211 and S212 of opening the axial connection hole, since the central point E of thethird connection hole 103 and the central point a of thereference hole 101 are distributed along the length direction of the artificialblood vessel body 100, the central point E of thethird connection hole 103 can be accurately positioned by measurement.
In the above embodiment, after the connection holes are opened in the circumferential direction, the connection holes are continuously opened in the axial direction on the surface of the artificialblood vessel body 100 with the same reference hole as a reference. It is understood that, in some other embodiments, an axial connection hole may be formed in the surface of the artificial blood vesselmain body 100, and then a circumferential connection hole may be formed based on the same reference hole, or after the circumferential/axial connection hole is formed, an axial/circumferential connection hole may be formed in the surface of the artificial blood vesselmain body 100 based on different reference holes, which is not limited herein.
The method for positioning the incision on the artificial blood vessel will be described in detail below by taking a specific embodiment as an example. The specification of the artificial blood vessel product is phi 28 × L500mm, four holes are cut, and the four holes are distributed in a T shape.
Areference hole 101, a second connectinghole 102, a third connectinghole 103 and a fourth connectinghole 104 are required to be formed in the artificial blood vesselmain body 100, the third connectinghole 103, thereference hole 101 and the fourth connectinghole 104 are axially arranged on the surface of the artificial blood vesselmain body 100 and are sequentially adjacent, the distance between the central points is set to be 20mm, and the diameter is set to be 12 mm; the second connection holes 102 and the reference holes 101 are circumferentially distributed on the surface of the artificial blood vesselmain body 100, the distance between the center points of the second connection holes 102 and the reference holes 101 is 19mm, and the diameter of the second connection holes 102 is 10 mm. The distances from the center points of the second connectinghole 102 and thereference hole 101 to the right end of the artificial blood vessel are set to be 166.7 mm.
Before cutting, the parameters of the laser cutting machine, such as cutting speed, cutting energy and cutting frequency, are set. The specific parameters are as follows: cutting speed 10%, cutting energy 8% and cutting frequency 80 Hz.
Firstly, a circumferential connecting hole group is arranged, and the method comprises the following steps:
step S110: positioning the center point of a reference hole on the surface of the artificial blood vessel body, such as the point A of thereference hole 101, wherein the distance from the center point A to the right end part of the artificial blood vessel is 166.7mm, and cutting the surface of the artificialblood vessel body 100 by using the radius r1 of thereference hole 101 as 6mm to form thereference hole 101;
step S120: and positioning a central point B of the second connectinghole 102 on the surface of the artificial blood vessel body along the same circumferential direction of the point A of thereference hole 101, positioning an opening starting point of the second connectinghole 102 on the surface of the artificial blood vessel body based on the preset radius r2 of the second connectinghole 102 being 5mm by taking the central point B as a center of a circle, and cutting to form the second connectinghole 102.
Specifically, the positioning step S120 operates as follows:
step S121: a connecting line between a central point a of thereference hole 101, a central point B of thesecond connection hole 102, and a center O of the artificial blood vesselmain body 100 in the same circumferential direction forms a triangle OAB, and it is known that a distance AB between the central point a of thereference hole 101 and the central point B of thesecond connection hole 102 is 19mm, and a radius R of the artificial blood vesselmain body 100 is 14mm, according to a triangle cosine theorem formula:
cos∠O=(2R2-AB2)/2R2 (1)
calculating to obtain cos & lt O & gt 0.079, and converting to obtain a central angle & lt O & gt 85.5 degrees of the central point of thereference hole 101 and the central point of the second connectinghole 102 in the same circumferential direction relative to the center of the artificial blood vesselmain body 100;
step S122: based on the degree of the central angle O and the radius R of the artificial blood vesselmain body 100 being 14mm, the arc length L of the connecting line of the central point A of thereference hole 101 and the central point B of the second connectinghole 102 on the surface of the artificial blood vesselmain body 100 is calculated according to the arc length formulaAB
LAB=(3.14*O*R)/180 (2)
LAB20.9mm, so as to locate the center point B of thesecond connection hole 102 on the surface of the artificialblood vessel body 100.
Step S123: as the radius r2 of thesecond connection hole 102 is known to be 5mm, the opening starting point D of thesecond connection hole 102 is located on the surface of the artificial blood vessel body with the center point B as the center based on the radius r2 being 5mm, and thesecond connection hole 102 is cut and formed.
Step S130: the central axis of the perforating device, such as a laser cutting machine, is opposite to the central point B of the second connectinghole 102, the position of a laser cutting head of the laser cutting machine is adjusted, a laser direct-emitting point D is formed, and the second connectinghole 102 is drilled on the surface of the artificial blood vesselmain body 100 according to r2 which is 5mm from the point D so as to form a hole.
After the connecting holes in the circumferential direction are formed, the connecting holes in the axial direction are continuously formed. The step of forming the connecting hole in the axial direction comprises the following steps:
step S210: selecting thecut reference hole 101 as a reference hole, and positioning a central point E of a third connectinghole 103 in the connecting holes in the axial direction; in this embodiment, thereference hole 101 serves as a reference for both the circumferential connection hole and the axial connection hole.
Step S210 specifically operates as follows:
step S211: locating the central point E of the third connectinghole 103 on the surface of the artificial blood vesselmain body 100 based on the distance AE between the central point E of the third connectinghole 103 and the central point A of thereference hole 101 being 20 mm;
step S212: positioning an opening starting point of the third connectinghole 103 on the surface of the artificial blood vessel main body, for example, a point G which is located on the same circumferential direction of the surface of the artificial blood vessel main body as the center point of the reference hole, based on the preset radius r3 of the third connectinghole 103 being 6mm, by taking the center point E of the third connectinghole 103 as the center of a circle, and cutting to form the third connectinghole 103;
step S220: and (3) the central shaft of the laser cutting machine is opposite to the central point of the third connectinghole 103, the position of a laser cutting head of the laser cutting machine is adjusted, so that the laser direct-emitting point G is formed by opening the third connectinghole 103 on the surface of the artificial blood vesselmain body 100 according to r3 which is 6mm from the point G, and a hole is formed.
After the third connectinghole 103 is formed, the center point of the fourth connectinghole 104 is continuously positioned by using thereference hole 101 as a reference according to the above operation mode, and a hole is formed by cutting with a laser cutting machine.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

CN202010218709.4A2020-03-252020-03-25Method for opening artificial blood vesselActiveCN113441851B (en)

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