Disclosure of Invention
The present invention is directed to a biopsy sampling device based on an endoscopic system to solve the above problems. In order to achieve the purpose, the invention provides the following technical scheme: an endoscopic system based biopsy sampling device, comprising:
the sampling device comprises an outer pipe, a sampling device and a control device, wherein a scraping roller for sampling is arranged in the outer pipe, and a sampling object obtained by the scraping roller is conveyed into a collecting box for collecting the sampling object through the outer pipe;
the inner pipe is arranged inside the outer pipe and used for conveying airflow to drive the scraping roller to rotate, so that the scraping roller performs sampling, and the sampling object is conveyed into the collection box through the outer pipe by utilizing the airflow;
and the air supply mechanism is communicated with the inner pipe and supplies air flow to the inner pipe, and the air supply mechanism can adjust the flow rate of the supplied air flow.
Preferably, the opening has been seted up on the lateral wall of outer tube, the both ends that lie in the opening on the inner wall of outer tube all are fixed with the baffle, and scrape the roller and lie in between two baffles, the central axis department of scraping the roller pegs graft and runs through there is the rotary drum, and the both ends of rotary drum run through respectively and the dead axle rotates to be connected on two baffles, be fixed with a plurality of acanthus leaf along the equidistant interval of circumference trend on the inner wall of rotary drum, acanthus leaf place plane is 40~50 contained angles with the central axis of rotary drum, the one end of rotary drum is pegged graft and the dead axle rotates and is connected with in the sleeve cap, and the sleeve cap is fixed and is connected the inner tube.
Preferably, a plurality of ribs with T-shaped cross sections are fixed on the outer side wall of the rotary drum along the circumferential direction, T-shaped grooves corresponding to the ribs are formed in the inner wall of the scraping roller, the ribs are inserted into the corresponding T-shaped grooves in the inner side wall of the scraping roller, a plurality of convex strips are integrally fixed on the outer side wall of the scraping roller at equal intervals along the circumferential direction, and a containing groove with an omega-shaped cross section is formed between every two adjacent convex strips.
Preferably, be fixed with on the outer tube inner wall and cut off, cut off the setting between two baffles, and cut off and set up the cylindricality cavity that link up, the roller setting of scraping sets up in the cavity and with cavity sharing the central axis setting, the cavity is linked together with the opening for scrape the roller and can take a sample through the opening, the baffle shelters from the cavity port that corresponds, and shelters from regional five-eighths to seven-eighths that account for cavity port area.
Preferably, the air supply mechanism comprises a regulating and controlling box, a pump shell and an air inlet cylinder are fixed on the regulating and controlling box, an air pipe is fixed and communicated on the outer side wall of the pump shell, one end of the air pipe is communicated with one end, far away from the scraping roller, of the inner pipe, the other end of the air pipe is communicated with the air inlet cylinder, and a filter screen for filtering and purifying air is fixed in the air inlet cylinder.
Preferably, the top wall of the regulating and controlling box is penetrated through and fixed-shaft rotation is connected with a first rotating shaft, the upper end of the first rotating shaft is fixedly connected with a rotating shaft of a pump wheel in the pump shell, the first rotating shaft is positioned at one end inside the regulating and controlling box and is fixedly connected with a first conical roller, the diameter of the upper end of the first conical roller is larger than that of the lower end of the first conical roller, a first motor is fixed inside the regulating and controlling box, the output shaft end of the first motor is fixedly connected with a second conical roller in a coaxial mode, the diameter of the upper end of the second conical roller is smaller than that of the lower end of the first conical roller, and the first conical roller and the second conical roller are identical in structure.
Preferably, a support is fixed on the inner wall of the regulating and controlling box, a second rotating shaft is rotatably connected to a fixed shaft on the support, the second rotating shaft is located between the first conical roller and the second conical roller, a friction roller is sleeved on the second rotating shaft, a flat key is fixed on the second rotating shaft, a key groove matched with the flat key is formed in the inner wall of the friction roller, the friction roller is simultaneously in buckling contact with the first conical roller and the second conical roller, and the second conical roller drives the first conical roller to rotate through the friction roller.
Preferably, one end of the friction roller is coaxially and rotationally connected with a rotating ring in a fixed-shaft manner, the rotating ring is sleeved outside the second rotating shaft, the outer side wall of the rotating ring is fixedly connected with a threaded sleeve through a connecting rod, the inner wall of the regulating and controlling box is fixedly provided with a second motor, the output shaft end of the second motor is in transmission connection with a screw rod rotationally connected to the inner wall of the regulating and controlling box through the fixed shaft, the threaded sleeve is sleeved on the screw rod in threaded connection, and the screw rod is parallel to the rotating shaft.
Preferably, one end of the friction roller is coaxially and fixedly connected with a ring plate in a rotating mode, the ring plate is sleeved outside the second rotating shaft, a sliding rod parallel to the second rotating shaft is fixed on the ring plate, the sliding rod penetrates through and is connected to the support in a sliding mode, a sliding rheostat is fixed on the inner wall of the regulating and controlling box, the sliding rheostat is connected into a circuit loop after being connected with a heating resistance wire wound on the outer side wall of the air pipe in series through a conducting wire, and one end, far away from the ring plate, of the sliding rod is fixedly connected with a sliding sheet on the sliding rheostat.
Preferably, run through on the lateral wall of air inlet cylinder and the dead axle rotates and is connected with reciprocating type lead screw, reciprocating type lead screw goes up the cover and establishes and sliding connection has the sliding sleeve of looks adaptation, be fixed with on the sliding sleeve and be used for the clear scraper blade of filter screen, be fixed with the guide arm that parallels with reciprocating type lead screw on the air inlet cylinder inner wall, and the guide arm runs through and sliding connection on the scraper blade, the coaxial fixed connection of one end of support is kept away from with two pivots to reciprocating type lead screw's one end, and two pivots run through and the dead axle rotates to be connected on the roof of regulation and control case.
Compared with the prior art, the invention has the beneficial effects that:
according to the invention, the scraping roller is driven to rotate in a pneumatic mode through the air supply mechanism, continuous sampling of the target sample is carried out, and the target sample is collected in the collection box by utilizing the airflow, so that the efficiency of sampling operation is improved, the pain of a patient caused by overlong sampling operation time is avoided, and the operation difficulty and risk are reduced.
According to the invention, the rotating speed of the pump wheel is adjusted by the air supply mechanism, so that the sampling speed is adjusted according to actual conditions, the use flexibility and the practicability are improved, and the sampling operation can be conveniently judged when to stop according to the amount of the target sample in the collection box.
According to the invention, the air supply mechanism supplies air and heats the air by using the heating resistance wire, the heating power can be correspondingly adjusted according to the air supply quantity, the air temperature is kept stable and close to the temperature of a human body, and cold and heat stimulation on the patient body caused by too low or too high temperature is avoided, so that the sampling operation safety is improved, and the damage to the patient body caused by sampling is avoided.
According to the invention, the air supply mechanism filters and purifies the air through the filter screen in the air conveying process, so that impurities in the air are prevented from polluting a target sample, and the cleaning efficiency of the filter screen can be adjusted in real time according to the conveyed air quantity, thereby maintaining the air filtering effect of the filter screen.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by workers skilled in the art without any inventive work based on the embodiments of the present invention, are within the scope of the present invention.
Referring to fig. 1 to 9, the present invention provides a technical solution: an endoscopic system based biopsy sampling device, comprising:
the sampling device comprises anouter tube 1, wherein ascraping roller 5 for sampling is arranged inside theouter tube 1, and a sampling object obtained by the scrapingroller 5 is conveyed into a collecting box 8 for collecting the sampling object through theouter tube 1;
the inner pipe 2 is arranged inside theouter pipe 1, and the inner pipe 2 is used for conveying airflow to drive the scrapingroller 5 to rotate, so that the scrapingroller 5 performs sampling, and the sampled object is conveyed into the collection box 8 through theouter pipe 1 by using the airflow;
and the air supply mechanism is communicated with the inner pipe 2 and supplies air flow into the inner pipe 2, and the air supply mechanism can adjust the flow rate of the supplied air flow.
In the embodiment, as shown in fig. 1, fig. 2, fig. 4, fig. 5 and fig. 6, a through hole 4 is formed on the side wall of an outer tube 1, baffles 6 are fixed on both ends of the through hole 4 on the inner wall of the outer tube 1, a scraping roller 5 is located between the two baffles 6, a rotating drum 10 is inserted and penetrated in the central axis of the scraping roller 5, both ends of the rotating drum 10 are respectively penetrated and connected to the two baffles 6 in a fixed-axis rotating manner, a plurality of blades 12 are fixed on the inner wall of the rotating drum 10 along the circumferential direction at equal intervals, an included angle of 40-50 degrees is formed between the plane where the blades 12 are located and the central axis of the rotating drum 10, one end of the rotating drum 10 is inserted and connected to the inside of a sleeve cap 3 in a fixed-axis rotating manner, the sleeve cap 3 is fixed and connected to the rotating drum 2, a plurality of protruding ribs 15 with T-shaped cross sections are fixed on the outer side wall of the rotating drum 10 along the circumferential direction, a T-shaped groove 16 corresponding to the protruding rib 15 is formed on the inner wall of the scraping roller 5, the protruding rib 15 is inserted and connected to the corresponding T-shaped groove 16 on the inner side wall of the scraping roller 5, the lateral wall of scraping roller 5 is fixed with a plurality of sand grips 14 along the equidistant integration of circumference trend, and form a cross-section between two adjacent sand grips and be the appearance groove 11 of omega form, the effect of the air current that inner tube 2 was carried is exerted to the leaf 12 effect that the slope set up, thereby drive rotary drum 10 and rotate, and then make rotary drum 10 drive scraping roller 5 through bead 15 and the mutual adaptation in T-slot 16 and rotate, bead 15 and the mutual adaptation in T-slot 16, improve driven stability between rotary drum 10 and the scraping roller 5, help improving the maneuverability to the sample sampling, and carry out the radius angle to the side of sand grip 14 and handle, can reduce the stimulation to the sampling position like this, avoid enlarging the damage.
In this embodiment, as shown in fig. 1, fig. 2, fig. 4, and fig. 5, apartition 7 is fixed on an inner wall of theouter tube 1, thepartition 7 is disposed between twobaffles 6, and a throughcylindrical cavity 13 is disposed on thepartition 7, the scrapingroller 5 is disposed in thecavity 13 and shares a central axis with thecavity 13, thecavity 13 is communicated with the throughopening 4, so that the scrapingroller 5 can sample through the throughopening 4, thebaffles 6 shield corresponding ports of thecavity 13, and the shielding area occupies seven eighths to eighths of the area of the ports of thecavity 13, and air flowing out of thedrum 10 can flow through the area of the cavity, which is not shielded by thebaffles 6, so as to collect the target sample in the containinggroove 11 through air flow.
In this embodiment, as shown in fig. 1, the air supply mechanism includes acontrol box 17, apump case 20 and anair inlet cylinder 27 are fixed on thecontrol box 17, anair pipe 21 is fixed and communicated on the outer side wall of thepump case 20, one end of theair pipe 21 is communicated with one end of the inner pipe 2 far away from the scrapingroller 5, the other end is communicated with theair inlet cylinder 27, afilter screen 28 for filtering and purifying air is fixed in theair inlet cylinder 27, and thefilter screen 28 purifies and filters air to prevent impurities in the air from polluting a target sample.
In this embodiment, as shown in fig. 1, 3 and 7, a firstrotating shaft 19 penetrates through and is connected to the top wall of the regulating and controllingbox 17 in a fixed-shaft rotating manner, the upper end of the firstrotating shaft 19 is fixedly connected to a rotating shaft of a pump wheel in apump housing 20, one end of the firstrotating shaft 19, which is located inside the regulating and controllingbox 17, is coaxially and fixedly connected to a first taperedroller 18, the upper end diameter of the first taperedroller 18 is larger than the lower end diameter, afirst motor 22 is fixed inside the regulating and controllingbox 17, the output shaft end of thefirst motor 22 is coaxially and fixedly connected to a second taperedroller 23, the upper end diameter of the second taperedroller 23 is smaller than the lower end diameter, and the first taperedroller 18 and the second taperedroller 23 have the same structure.
In this embodiment, as shown in fig. 3, 8 and 9, a support 24 is fixed on an inner wall of the regulating and controlling box 17, a second rotating shaft 41 is rotatably connected to a fixed shaft on the support 24, the second rotating shaft 41 is located between the first tapered roller 18 and the second tapered roller 23, the second rotating shaft 41 is sleeved with a friction roller 35, a flat key 42 is fixed on the second rotating shaft 41, a key slot 43 matched with the flat key 42 is formed on an inner wall of the friction roller 35, the friction roller 35 is simultaneously in abutting contact with the first tapered roller 18 and the second tapered roller 23, the first tapered roller 18 is driven to rotate by the friction roller 35, one end of the friction roller 35 is coaxially and rotatably connected with a rotating ring 34 through the fixed shaft, the rotating ring 34 is sleeved outside the second rotating shaft 41, an outer side wall of the rotating ring 34 is fixedly connected with a threaded sleeve 37 through a connecting rod 36, a second motor 39 is fixed on the inner wall of the regulating and controlling box 17, an output of the second motor 39 is connected with a transmission shaft end of a threaded rod 38 rotatably connected to the inner wall of the regulating and controlling box 17, and the swivel nut 37 is sleeved and screwed on the screw rod 38, the screw rod 38 and the second rotating shaft 41 are arranged in parallel, and the rotating speed of the pump wheel in the pump shell 20 is adjusted by adjusting the position of the friction roller 35, so that the sampling speed can be adjusted according to actual conditions, and the use flexibility and the practicability are improved.
In this embodiment, as shown in fig. 3, one end of the friction roller 35 is coaxially and rotatably connected with a ring plate 33, the ring plate 33 is sleeved outside the second rotating shaft 41, a sliding rod 25 parallel to the second rotating shaft 41 is fixed on the ring plate 33, the sliding rod 25 penetrates and is slidably connected to the bracket 24, a sliding rheostat 26 is fixed on the inner wall of the regulating and controlling box 17, the sliding rheostat 26 is connected in series with a heating resistance wire 40 wound on the outer side wall of the air tube 21 through a conducting wire and then is connected into a circuit loop, one end of the sliding rod 25 away from the ring plate 33 is fixedly connected with a sliding sheet 32 on the sliding rheostat 26, the air in the air tube 21 is heated after the heating resistance wire 40 is electrified, so that the air keeps close to the temperature of the human body in the process of flowing in the inner tube 2 and the outer tube 1, the temperature is prevented from taking away heat from the inside of the human body, cold stimulation is generated in the patient body, and the thermal stimulation is also prevented from being generated in the patient body by the over-temperature, thereby increasing the safety of sampling operation and avoiding the damage of sampling to the body of the patient.
In this embodiment, as shown in fig. 1, a reciprocating lead screw 29 is connected to a side wall of theair inlet cylinder 27 in a penetrating and fixed-axis rotating manner, a sliding sleeve 30 matched with the reciprocating lead screw 29 is sleeved and connected to the reciprocating lead screw 29 in a sliding manner, ascraper 31 for cleaning thefilter screen 28 is fixed to the sliding sleeve 30, aguide rod 44 parallel to the reciprocating lead screw 29 is fixed to an inner wall of theair inlet cylinder 27, theguide rod 44 is connected to thescraper 31 in a penetrating and sliding manner, one end of the reciprocating lead screw 29 and one end of the secondrotating shaft 41, which are far away from the bracket 24, are coaxially and fixedly connected, the secondrotating shaft 41 is connected to a top wall of the regulating and controllingbox 17 in a penetrating and fixed-axis rotating manner, thescraper 31 is driven by the reciprocating lead screw 29 to clean thefilter screen 28, so as to maintain a filtering effect of thefilter screen 28.
The use method and the advantages of the invention are as follows: when the biopsy sampling device based on the endoscopic system is used for biopsy sampling, the working process is as follows:
as shown in fig. 1, theouter tube 1 is extended into the sampling site of the patient by manipulating the outer tube under the guidance of the endoscopic system, and the throughopening 4 of theouter tube 1 is directed to the sampling site so as to allow thescraping roller 5 to be brought into abutting contact with the surface of the sampling site through the throughopening 4.
Starting the motor I22 to work, as shown in fig. 1 and fig. 3, after the motor I22 works, driving the conical roller II 23 to rotate, so that the conical roller II 23 drives the conical roller I18 to rotate through the friction roller 35, so that the conical roller I18 drives the pump wheel inside the pump housing 20 to rotate through the rotating shaft I19, so that the pump wheel conveys air into the inner tube 2 through the air tube 21 and conveys the air into the rotary drum 10 from the inner tube 2, when the air flow passes through the rotary drum 10, an action is exerted on the obliquely arranged blades 12, so that the blades 12 drive the rotary drum 10 to rotate on the baffle 6, and further the rotary drum 10 synchronously drives the scraping roller 5 to rotate, wherein the rotary drum 10 and the scraping roller 5 are mutually matched and connected through the convex ribs 15 and the T-shaped grooves 16, so that the connection stability is increased, so that the rotary drum 10 can stably and firmly drive the scraping roller 5 to rotate, so as to improve the transmission stability and facilitate the operability of sampling samples, when the scraping roller 5 rotates, as shown in fig. 4 and fig. 6, the scraping roller 5 is in contact with the surface of the sampling position through the side edge of the convex strip 14, and scrapes target samples such as mucosal epidermal cells, tissues and body fluids on the sampling surface, and stores the target samples in the corresponding containing groove 11, the side edge of the convex strip 14 is subjected to chamfering treatment, and the scraping roller 5 and the convex strip 14 are both made of medical rubber or medical silica gel, so that stimulation to the sampling position is reduced, damage caused by expansion is avoided, after the convex strip 14 scrapes the target samples and stores the target samples in the containing groove 11, the containing groove 11 drives the target samples stored inside to move towards the inside of the concave cavity 13 along with the rotation of the scraping roller 5, and the target samples in the containing groove 11 are collected.
As shown in fig. 1, 2, 4 and 5, after the air flow passes through the rotary drum 10, as shown by the white arrows in fig. 1 and 2, the air flow encounters the inner wall of the end portion of the outer tube 1 and flows in the opposite direction, so that the air flow enters the cavity 13 through the region where the end portion of the cavity 13 is not shielded by the baffle 6, and the air flow enters the container 11 through the end portion of the corresponding container 11 located at the region where the end portion of the corresponding cavity 13 is not shielded by the baffle 6, the air flow drives the target sample in the container 11 to flow out from the region where the other end of the cavity 13 is not shielded by the baffle 6 inside the container 11, thereby discharging the target sample in the container 11, so that the emptied container 11 is driven by the scraping roller 5 to sample again, and the cycle is repeated, thereby improving the efficiency of the sampling operation, avoiding the pain of the patient caused by the overlong sampling operation time, and the air flow in the opposite direction in the space between the outer tube 1 and the inner tube 2, and drive the target sample to get into through pipe 9 and collect in the box 8, realize the collection to the target sample to realize the sample operation to the target sample, and reduced the operation degree of difficulty and patient's misery, can be convenient for judge when to stop sample operation according to the volume of the target sample in collecting the box 8 in addition, and technical scheme realizes continuous sampling in addition, need not to pass through the internal sample of passing in and out patient many times, improves sampling efficiency, reduces patient's misery and risk.
As shown in fig. 1, 3 and 8, during sampling, the second motor 39 is started to drive the screw 38 to rotate, the screw 38 drives the screw sleeve 37 to move on the screw 38 through screw transmission, so that the screw sleeve 37 synchronously drives the rotating ring 34 through the connecting rod 36, and further the rotating ring 34 synchronously drives the friction roller 35 to move on the second rotating shaft 41, so that the friction roller 35 moves between the first conical roller 18 and the second conical roller 23, since the diameters of the first conical roller 18 and the second conical roller 23 are different from top to bottom, the transmission ratio of the first conical roller 18 to the second conical roller 23 is different, the diameter of the first conical roller 18 is gradually larger from top to bottom, the diameter of the second conical roller 23 is gradually smaller from top to bottom, so that the transmission ratio of the first conical roller 18 to the second conical roller 23 is gradually larger when the friction roller 35 moves downwards, the transmission ratio of the first conical roller 18 to the second conical roller 23 is gradually smaller when the friction roller 35 moves upwards, thereby realize the regulation to pump wheel rotational speed in the pump case 20, and then realize the regulation to sampling speed, can adjust sampling speed like this according to actual conditions, improve and use flexibility and practicality.
As mentioned above, in the process of sampling, the circuit composed of the heating resistance wire 40 and the sliding rheostat 26 is energized while the motor I22 is started, so that the heating resistance wire 40 heats the air in the air pipe 21 after being energized, the temperature of the air is kept close to the temperature of the human body in the process of flowing in the inner pipe 2 and the outer pipe 1, the phenomenon that the temperature is too low to take away heat from the interior of the human body to generate cold stimulation to the interior of the patient body is avoided, the phenomenon that the temperature is too high to generate thermal stimulation to the interior of the patient body is also avoided, the safety of sampling operation is improved, and the damage to the interior of the patient body caused by sampling is avoided, as shown in figures 1 and 3, in the process of moving the friction roller 35 up and down, when the friction roller 35 moves down, the ring plate 33 and the sliding rod 25 drive the sliding sheet 32 to move down on the sliding rheostat 26 to reduce the resistance, the downward movement of the friction roller 35 increases the speed of conveying the air by the pump wheel, and simultaneously drives the resistance of the sliding rheostat 26 to reduce, the electric heating power of the heating resistance wire 40 is improved, so that the air temperature entering the inner tube 2 and the outer tube 1 is not reduced due to the increase of the air flow, the speed of conveying air by the pump wheel is reduced due to the upward movement of the friction roller 35, meanwhile, the resistance of the sliding rheostat 26 is increased, the electric heating power of the heating resistance wire 40 is reduced, the air temperature entering the inner tube 2 and the outer tube 1 is not increased due to the reduction of the air flow, and the temperature of the air conveyed to the inner tube 2 and the temperature of the air conveyed to the inner tube 1 are stable.
As described above, in the process of sampling, the pump wheel in the pump housing 20 sucks air from the air inlet tube 27 through the air tube 21 and conveys the air into the inner tube 2, the air enters the air tube 21 after being filtered and purified by the filter screen 28 in the air inlet tube 27, so that impurities in the air are prevented from polluting a target sample, the transmission ratio of the second conical roller 23 to the friction roller 35 is reduced or increased in the process that the friction roller 35 moves up and down, as shown in fig. 1, 3, 8 and 9, so that the friction roller 35 synchronously drives the second rotating shaft 41 to rotate under the transmission action of the key slot 43 and the flat key 42, the rotating speed of the friction roller 35 is increased when the friction roller 35 moves down, so that the rotating speed of the second rotating shaft 41 is increased, the rotating speed of the friction roller 35 is reduced when the friction roller 35 moves up, so that the rotating speed of the second rotating shaft 41 is reduced, and the rotating speed of the second rotating shaft 41 is synchronously driven to rotate at the reciprocating screw 29, and then the reciprocating screw 29 drives the scraper 31 to clean the filter screen 28 through the adaptive sliding sleeve 30, so that the filtering effect of the filter screen 28 is kept, and the rotating speed of the second rotating shaft 41 is synchronously increased while the air conveying amount is increased by moving the friction roller 35 downwards, so that the cleaning efficiency of the scraper 31 on the filter screen 28 is correspondingly improved, and the cleaning efficiency on the filter screen 28 is kept in real time.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and the preferred embodiments of the present invention are described in the above embodiments and the description, and are not intended to limit the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.