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CN113040903A - Laser ablation system - Google Patents

Laser ablation system
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Publication number
CN113040903A
CN113040903ACN202110310473.1ACN202110310473ACN113040903ACN 113040903 ACN113040903 ACN 113040903ACN 202110310473 ACN202110310473 ACN 202110310473ACN 113040903 ACN113040903 ACN 113040903A
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China
Prior art keywords
optical waveguide
catheter
laser ablation
channel
optical
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Chinese (zh)
Inventor
于波
康维
候静波
贾海波
赵晨
徐晨阳
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Panoramic Hengsheng Beijing Science And Technology Co ltd
Harbin Medical University
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Panoramic Hengsheng Beijing Science And Technology Co ltd
Harbin Medical University
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Priority to CN202110310473.1ApriorityCriticalpatent/CN113040903A/en
Publication of CN113040903ApublicationCriticalpatent/CN113040903A/en
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Abstract

Translated fromChinese

本申请提供一种激光消蚀系统,包括导管;消蚀装置,消蚀装置包括激光发射器和第一光波导,第一光波导设于导管中,用于将由激光发射器发出的第一光束从导管的近端传播至导管的远端;以及OCT成像装置,OCT成像装置包括成像引擎、第二光波导和第一光学元件组,第二光波导设于导管中,用于将由成像引擎发出的第二光束从近端传播至远端;第一光学元件组设于远端,且位于第二光束的传播路径上,用于使第二光束的聚焦点位于第一光波导的前方。成像装置能够提供血管的内窥图像,能帮助医生准确判断病灶的位置和形态,从而确定激光消蚀术的治疗参数。完成激光消蚀术后,成像装置能帮助医生评价治疗效果,从而便于制定下一步手术计划。

Figure 202110310473

The application provides a laser ablation system, including a catheter; an ablation device, the ablation device includes a laser transmitter and a first optical waveguide, the first optical waveguide is arranged in the catheter, and is used for the first light beam emitted by the laser transmitter. Propagating from the proximal end of the catheter to the distal end of the catheter; and an OCT imaging device, the OCT imaging device comprising an imaging engine, a second optical waveguide and a first optical element group, the second optical waveguide being provided in the catheter for converting the light emitted by the imaging engine The second beam propagates from the proximal end to the distal end; the first optical element group is arranged at the distal end, and is located on the propagation path of the second beam, so that the focusing point of the second beam is located in front of the first optical waveguide. The imaging device can provide endoscopic images of blood vessels, which can help doctors to accurately determine the location and shape of the lesions, so as to determine the treatment parameters of laser ablation. After laser ablation is completed, the imaging device can help the doctor evaluate the treatment effect, so as to facilitate the planning of the next surgery.

Figure 202110310473

Description

Laser ablation system
Technical Field
The invention relates to the field of medical equipment, in particular to a laser ablation system.
Background
Percutaneous coronary artery interventional therapy usually sends a guide catheter to a coronary artery opening to be expanded, then sends a balloon with a corresponding size to a narrow section along a guide wire, and expands with proper pressure and time according to the characteristics of lesions to achieve the purpose of relieving arterial stenosis. Traditional treatment approaches include angioplasty or stent implantation. Plaque ablation is a cardiac intervention assisted treatment technique, including rotational atherectomy and laser ablation of plaque in the coronary artery lumen. In recent years, the excimer laser coronary plaque ablation uses a catheter design and a pulse-type emitted ultraviolet cold light source, so that the effectiveness and the safety of the operation are improved. The ultraviolet laser light source can be effectively absorbed by biological tissues and can provide enough energy to destroy intermolecular forces of surface tissues. At the same time, the absorption of light by the tissue causes a local temperature rise and causes photo-acoustic and photo-thermal ablation effects, which can further ablate a thin layer of the tissue surface onto which the light is directed, with little effect on the surrounding tissue. After the catheter smoothly passes through the pathological changes, the balloon can be used for fully expanding and implanting the stent, and the revascularization can be completed.
The inventor researches and discovers that the existing excimer laser spot ablation has the following defects:
the safety and the accuracy are poor.
Disclosure of Invention
The invention aims to provide a laser ablation system which can improve the safety and accuracy of ablation so as to improve the success rate of operation.
The embodiment of the invention is realized by the following steps:
the invention provides a laser ablation system, comprising:
a conduit;
an ablation device comprising a laser emitter and a first optical waveguide disposed in the catheter for propagating a first light beam emitted by the laser emitter from the proximal end of the catheter to the distal end of the catheter;
and an OCT (optical coherence tomography) imaging device comprising an imaging engine, a second optical waveguide disposed in the catheter for propagating a second light beam emitted by the imaging engine from the proximal end to the distal end, and a first set of optical elements; the first optical element group is arranged at the far end, is positioned on the propagation path of the second light beam and is used for enabling the focusing point of the second light beam to be positioned in front of the first optical waveguide.
In an alternative embodiment, the conduit is provided with a first channel and a second channel independent of each other, the first optical waveguide being provided in the first channel; the second optical waveguide and the first optical element group are both arranged in the second channel.
In an alternative embodiment, the laser ablation system further comprises an adapter connected to the proximal end of the catheter, the first optical waveguide and the second optical waveguide both extending through the adapter.
In an alternative embodiment, the catheter is provided with a third channel through which a guide wire is threaded.
In an alternative embodiment, the first optical waveguides are provided in a plurality, and the distal end faces of the plurality of first optical waveguides are located in the same plane.
In an alternative embodiment, the region defined by the distal end faces of the first plurality of optical waveguides is disposed off-center from the axis of the conduit.
In an alternative embodiment, the regions defined by the distal end faces of the first plurality of optical waveguides are each disposed coaxially with the axis of the conduit.
In an alternative embodiment, the distal end face of the first optical element group is arranged coaxially with the axis of the catheter.
In an optional embodiment, the OCT imaging device further includes a conducting optical fiber, a collimator, a galvanometer scanner, and a second optical element group, and the first light beam propagates to the second optical waveguide after passing through the conducting optical fiber, the collimator, the galvanometer scanner, and the second optical element group in sequence.
In an alternative embodiment, the peripheral wall of the conduit is provided with a developing portion.
The embodiment of the invention has the beneficial effects that:
in summary, the present embodiment provides a laser ablation system, in which a first optical waveguide and a second optical waveguide are integrated in a catheter, the first optical waveguide is used for transmitting a first light beam for laser ablation, and transmitting laser light from a proximal end to a distal end of the catheter, so as to exit from the distal end and act on human tissue to ablate the tissue. The second optical waveguide is used for transmitting a second light beam for imaging, the second light beam is transmitted from the near end to the far end and is emitted from the far end, the second light beam passes through the first optical element group when being emitted from the far end, and the first optical element group enables the focusing point of the second light beam to be located in front of the first optical waveguide, so that the tissue in front of the first optical waveguide is visualized, and therefore laser ablation of the tissue in front of the first optical waveguide is facilitated. In other words, the tissue is subjected to laser ablation under the visual condition, so that the safety and the reliability are high, and the surgical events such as interlayer or perforation caused by damage to the healthy tissue by laser are not easy to occur.
Meanwhile, the imaging device can provide an endoscopic image of the blood vessel, and can help a doctor to accurately judge the position and the form of a focus, so that the treatment parameters of the laser ablation are determined. After the laser ablation is completed, the imaging device can help a doctor to evaluate the treatment effect, so that a next operation plan can be conveniently made.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic diagram of a laser ablation system according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of a distal end structure of a laser ablation system according to an embodiment of the present invention;
FIG. 3 is a schematic cross-sectional view of a laser ablation system according to an embodiment of the present invention;
FIG. 4 is a schematic structural diagram of an oct imaging device according to an embodiment of the present invention;
FIG. 5 is a schematic diagram of a modified embodiment of a laser ablation system according to the present invention;
FIG. 6 is a schematic cross-sectional view of the embodiment of the present invention corresponding to FIG. 5;
fig. 7 is a schematic structural diagram of another variation of the laser ablation system according to the embodiment of the present invention.
Icon:
100-a catheter; 101-back end; 102-a front end; 103-tube wall; 104-an adaptor; 105-a laser emitter; 106-an imaging engine; 107-a first optical waveguide; 108-a second optical waveguide; 109-a first optical element group; 110-a third channel; 203-a guide wire; 204-a developing part; 301-axis; 302-a second light beam; 303-focus point; 401-conducting optical fiber; 402-an outgoing light beam; 403-a collimator; 404-galvanometer scanner; 405-parallel beams; 406-a second group of optical elements; 407-proximal end face.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings or the orientations or positional relationships that the products of the present invention are conventionally placed in use, and are only used for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the devices or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.
Furthermore, the terms "horizontal", "vertical" and the like do not imply that the components are required to be absolutely horizontal or pendant, but rather may be slightly inclined. For example, "horizontal" merely means that the direction is more horizontal than "vertical" and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.
In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
At present, thecatheter 100 is implanted into a diseased position of a human body for ablation treatment of tissues in the laser ablation, and the condition of the tissues at thefront end 102 of thecatheter 100 is not easy to observe because thefront end 102 of thecatheter 100 is a sight blind area, so that the ablation treatment difficulty is increased, the operation time is prolonged, the treatment effect is poor, and the operation success rate is low.
Referring to fig. 1-7, in view of the above, the present embodiment provides an integrated imaging andlaser ablation catheter 100 system, which can observe the tissue image of thefront end 102 of thecatheter 100 in real time during the ablation treatment process, thereby reducing the difficulty of the ablation treatment, shortening the operation time, and increasing the success rate of the operation.
In this embodiment, it should be noted that, as will be understood by those skilled in the art, thefront end 102 of thecatheter 100 is in contact with the human body and therear end 101 of thecatheter 100 is provided for the operation of the operator when thecatheter 100 system is in use, and for the convenience of description, the end of each component of thecatheter 100 system near thefront end 102 of thecatheter 100 is referred to as a distal end, and the end of each component near therear end 101 of thecatheter 100 is referred to as a proximal end.
Referring to fig. 1-3, in the present embodiment, the laser ablation system includes acatheter 100, an ablation device, and an OCT imaging device. The ablation device comprises alaser emitter 105 and a firstoptical waveguide 107, the firstoptical waveguide 107 being arranged in thecatheter 100 for propagating a first light beam emitted by thelaser emitter 105 from the proximal end of thecatheter 100 to the distal end of thecatheter 100. The OCT imaging device comprises animaging engine 106, a secondoptical waveguide 108 and a first optical element set 109, the secondoptical waveguide 108 being provided in thecatheter 100 for propagating asecond light beam 302 emitted by theimaging engine 106 from the proximal end to the distal end; the firstoptical element group 109 is disposed at the distal end, is located on the propagation path of thesecond light beam 302, and is configured to position thefocal point 303 of thesecond light beam 302 in front of the firstoptical waveguide 107.
The present embodiment provides a laser ablation system, in which a firstoptical waveguide 107 and a secondoptical waveguide 108 are integrated in acatheter 100, the firstoptical waveguide 107 is used for transmitting a first light beam for laser ablation, and transmitting laser light from a proximal end to a distal end of thecatheter 100, so as to exit from the distal end and act on human tissue to ablate the tissue. The secondoptical waveguide 108 is used for transmitting a secondlight beam 302 for imaging, the secondlight beam 302 is transmitted from the near end to the far end and is emitted from the far end, and the secondlight beam 302 passes through the firstoptical element group 109 when being emitted from the far end, the firstoptical element group 109 enables thefocus point 303 of the secondlight beam 302 to be positioned in front of the firstoptical waveguide 107, so that the tissue in front of the firstoptical waveguide 107 can be visualized, and therefore laser ablation of the tissue in front of the firstoptical waveguide 107 is facilitated. In other words, the tissue is subjected to laser ablation under the visual condition, so that the safety and the reliability are high, and the surgical events such as interlayer or perforation caused by damage to the healthy tissue by laser are not easy to occur.
Meanwhile, the imaging device can provide an endoscopic image of the blood vessel, and can help a doctor to accurately judge the position and the form of a focus, so that the treatment parameters of the laser ablation are determined. After the laser ablation is completed, the imaging device can help a doctor to evaluate the treatment effect, so that a next operation plan can be conveniently made.
Referring to fig. 2, in the present embodiment, theconduit 100 is optionally configured as an elongated cylindrical pipe, that is, the cross-sectional shape of theconduit 100 is a circular ring. The lumen of thecatheter 100 includes a first channel, a second channel and athird channel 110 which are independently provided from each other, and thethird channel 110 is a cylindrical through hole and is coaxially provided with thecatheter 100. The two ends of the first channel, the second channel and thethird channel 110 extend to the proximal end face and the distal end face of thecatheter 100 respectively, the cross-sectional shapes of the first channel and the second channel are semicircular, the first channel and the second channel are arranged around thethird channel 110, and the first channel and the second channel form a substantially circular channel together. It should be understood that the first channel and the second channel are both eccentrically arranged, that is, the first channel and the second channel are eccentrically arranged relative to theaxis 301 of thecatheter 100, and since the first channel is used for assembling the firstoptical waveguide 107 and the second channel is used for assembling the secondoptical waveguide 108, in the laser ablation process, thecatheter 100 can be rotated, so as to adjust the position of the first channel, and further adjust the position of the firstoptical waveguide 107 located in the first channel, so as to realize the position of laser emission, so that the tissue at different positions can be subjected to laser ablation, and the use is more flexible and reliable.
It should be noted that, in other embodiments, the first channel and the second channel may not be semicircular rings, that is, the ratio of the cross-sectional areas of the two channels may not be 1:1, for example, the first channel may also be a circular ring with a central angle of 200 °, and correspondingly, the second channel may be a circular ring with a central angle of 160 °.
Referring to fig. 5-7, in addition, in other embodiments, the first channel and the second channel may be coaxially disposed, that is, both coaxial with theaxis 301 of thecatheter 100, so that both the first channel and the second channel are circular rings, and further, the first channel may be located between thethird channel 110 and the second channel, or the second channel may be located between the first channel and thethird channel 110.
In other embodiments, the portion of thethird channel 110 is coaxial with theaxis 301 of thecatheter 100, the distal end of thethird channel 110 is concentric with the distal end of thecatheter 100, and the proximal end of thethird channel 110 extends through thewall 103 of thecatheter 100, i.e., the proximal end of thethird channel 110 is located on the outer tubular wall of thecatheter 100 and not on the proximal face of thecatheter 100. In this manner, when theguidewire 203 is inserted through thethird channel 110, the proximal end of theguidewire 203 extends out of thewall 103 of thecatheter 100.
It will be appreciated that the region of the distal end face of thecatheter 100 is divided into three separate regions, i.e. the distal end of the first channel is defined as the first region, the distal end of the second channel is defined as the second region, and the distal end of thethird channel 110 is defined as the third region, and the first region, the second region and the third region are all located on the same plane, i.e. on the distal end face of thecatheter 100.
Optionally, the distal end face of thecatheter 100 is a circular flat face.
Optionally, the outer peripheral wall of thecatheter 100 is provided with avisualization portion 204, and thevisualization portion 204 may be a ring-shaped marker structure made of an X-ray shielding material, so as to display the position of thecatheter 100 system in the blood vessel during angiography.
Optionally, the proximal end of thecatheter 100 is provided with anadapter 104, theadapter 104 is provided with two holes for the firstoptical waveguide 107 and the secondoptical waveguide 108 to penetrate through, respectively, and theadapter 104 plays a role in stabilizing the firstoptical waveguide 107 and the secondoptical waveguide 108.
In this embodiment, thecatheter 100 may be directly and integrally formed into a structure having the first channel, the second channel and thethird channel 110, or thecatheter 100 is first formed into a tube having a lumen, and then a separator is disposed in the tube, so as to separate the lumen of thecatheter 100 into the first channel, the second channel and thethird channel 110.
In this embodiment, the wavelength of the laser emitted from thelaser emitter 105 is optionally selected from an ultraviolet band with strong ablation effect, such as a Nd: YAG (Neodymium-doped yttrium aluminum garnet crystal) triple harmonic laser or an excimer laser. Specifically, the wavelength of the Nd-YAG triple harmonic laser is 355 nm, and the energy flux of each pulse generating ablation is at least 50mJ/mm 2. Optionally, the frequency of the pulses emitted from the firstoptical waveguide 107 is at least 10Hz, and further, the frequency of the pulses emitted from the firstoptical waveguide 107 is between 25Hz and 40 Hz. The excimer laser has a wavelength of 308 nm and an energy fluence per pulse to produce ablation of at least 30mJ/mm 2. Optionally, the frequency of the pulses emitted from the firstoptical waveguide 107 is at least 10Hz, and further, the frequency of the pulses emitted from the firstoptical waveguide 107 is between 25Hz and 40 Hz.
In this embodiment, optionally, the firstoptical waveguide 107 is provided in a plurality of pieces, each of the firstoptical waveguides 107 is an optical fiber with a circular cross section, peripheral walls of the optical fibers are fitted to each other and arranged in the first channel, each of the optical fibers extends along the extending direction of thecatheter 100, a distal end face of each of the optical fibers is located in the first region, and a proximal end of each of the optical fibers extends out of the proximal end of thecatheter 100. It should be understood that the number of optical fibers is selected as desired according to the diameter thereof and the cross-sectional area of the first passage, and is not particularly limited herein.
It should be understood that when the first channel is semi-circular, the plurality of firstoptical waveguides 107 are arranged within the first channel and are substantially semi-circular. When the first channel is circular, the plurality of firstoptical waveguides 107 are arranged in the first channel and have a substantially circular shape.
Referring to fig. 4, in this embodiment, optionally, the OCT imaging device includes a conductingoptical fiber 401, acollimator 403, agalvanometer scanner 404, and a secondoptical element group 406, and the first light beam sequentially passes through the conductingoptical fiber 401, thecollimator 403, thegalvanometer scanner 404, and the secondoptical element group 406 and then propagates to the secondoptical waveguide 108. The secondoptical waveguide 108 is provided as a single mode optical fiber bundle. In operation of the OCT imaging apparatus, the secondlight beam 302 guided from theimaging engine 106 propagates through the guidingfiber 401, and anoutgoing light beam 402 emitted from the guidingfiber 401 is changed into aparallel light beam 405 by thecollimator 403 and then is incident on agalvanometer scanner 404. Thegalvanometer scanner 404 may redirect theparallel beam 405 to achieve a raster scan. The parallellight beams 405 are incident on the secondoptical element group 406 such that the focal points of the raster-scanned parallel light are each located on theproximal end face 407 of the secondoptical waveguide 108. The secondoptical waveguide 108 is a single-mode fiber bundle with a cutoff frequency at least less than the broadband light source-15 dB lower bandwidth limit wavelength to ensure single-mode propagation of the secondlight beam 302 in the secondoptical waveguide 108.
It should be understood that the purpose of the present embodiment of using raster scanning and single-mode fiber bundle to realize laser propagation is to activate one or a few fibers in the single-mode fiber bundle at a time to conduct OCT imaging light using raster scanning. The single mode fiber is activated in sequence to realize raster scanning at the far end of the catheter, and further realize far-end scanning imaging of OCT.
Optionally, the secondoptical waveguide 108 is an optical fiber with a circular cross-section and a uniform cross-sectional area. Optionally, the numerical aperture of the optical fiber is between 0.1 and 0.5, and further, the numerical aperture of the optical fiber is between 0.3 and 0.4.
It should be understood that when the second channel is semi-circular, the plurality of secondoptical waveguides 108 are arranged within the second channel and are substantially semi-circular. When the second channel is circular, the plurality of secondoptical waveguides 108 are arranged in the second channel and have a substantially circular shape. Moreover, the second optical element set 406 is disposed in the second channel and located at the proximal end side of the secondoptical waveguide 108, so that the secondoptical waveguide 108 needs to pass through the second optical element set 406 and then be emitted from the distal end surface of thecatheter 100.
In this embodiment, optionally, the firstoptical element group 109 may be configured as a lens group, for example, including a plurality of lenses arranged in sequence in the extending direction of thecatheter 100, after the secondlight beam 302 simultaneously passes through the lens group, the focusingpoint 303 of the secondlight beam 302 is located in front of the firstoptical waveguide 107, so as to image the tissue to be ablated in front of the firstoptical waveguide 107. The secondoptical element group 406 may be configured as a telescopic lens group.
It will be appreciated that the ease of ablation may be improved by adjusting the position and configuration of the first optical assembly such that after the secondlight beam 302 passes through the first optical assembly, thefocal point 303 of the secondlight beam 302 is located directly in front of the firstoptical waveguide 107.
The laser ablation system of this embodiment combines an imaging device with laser ablation, and the firstoptical waveguide 107 enables optical energy to be delivered to the focal region for laser ablation. The arrangement of the secondoptical waveguide 108, the relative position of the first optical element set 109 at the distal end of thecatheter 100, and the design of the first optical element set 109 enable the OCT imaging device to image the vascular tissue directly in front of the firstoptical waveguide 107. Thecatheter 100 system not only retains the treatment effect of the laser ablation, but also provides OCT image guidance, and can promote the application of the laser ablation in eccentric type vascular stenosis. When laser ablation is carried out, the OCT imaging device can provide an endoscopic image of a blood vessel and can help a doctor to accurately judge the position and the form of a focus, so that the treatment parameters of the laser ablation are determined. After the laser ablation is completed, the OCT imaging device can help doctors to evaluate the treatment effect, so that the next operation plan is made.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

Translated fromChinese
1.一种激光消蚀系统,其特征在于,包括:1. a laser ablation system, is characterized in that, comprises:导管;catheter;消蚀装置,所述消蚀装置包括激光发射器和第一光波导,所述第一光波导设于所述导管中,用于将由所述激光发射器发出的第一光束从所述导管的近端传播至所述导管的远端;An ablation device, the ablation device includes a laser emitter and a first optical waveguide, the first optical waveguide is arranged in the conduit, and is used for sending the first light beam emitted by the laser emitter from the conduit of the conduit The proximal end propagates to the distal end of the catheter;以及OCT成像装置,所述OCT成像装置包括成像引擎、第二光波导和第一光学元件组,所述第二光波导设于所述导管中,用于将由所述成像引擎发出的第二光束从所述近端传播至所述远端;所述第一光学元件组设于所述远端,且位于所述第二光束的传播路径上,用于使所述第二光束的聚焦点位于所述第一光波导的前方。and an OCT imaging device, the OCT imaging device includes an imaging engine, a second optical waveguide and a first optical element group, wherein the second optical waveguide is arranged in the conduit for converting the second light beam emitted by the imaging engine Propagating from the proximal end to the distal end; the first optical element group is arranged at the distal end, and is located on the propagation path of the second light beam, so that the focusing point of the second light beam is located at the front of the first optical waveguide.2.根据权利要求1所述的激光消蚀系统,其特征在于:2. The laser ablation system according to claim 1, wherein:所述导管设有相互独立的第一通道和第二通道,所述第一光波导设于所述第一通道中;所述第二光波导和所述第一光学元件组均设于所述第二通道中。The conduit is provided with a first channel and a second channel independent of each other, the first optical waveguide is arranged in the first channel; the second optical waveguide and the first optical element group are both arranged in the in the second channel.3.根据权利要求1所述的激光消蚀系统,其特征在于:3. The laser ablation system according to claim 1, wherein:所述激光消蚀系统还包括转接件,所述转接件与所述导管的近端连接,所述第一光波导和所述第二光波导均贯穿所述转接件。The laser ablation system further includes an adapter, the adapter is connected with the proximal end of the catheter, and both the first optical waveguide and the second optical waveguide pass through the adapter.4.根据权利要求1所述的激光消蚀系统,其特征在于:4. The laser ablation system according to claim 1, wherein:所述导管设有供导丝穿设的第三通道。The catheter is provided with a third channel for the guide wire to pass through.5.根据权利要求1所述的激光消蚀系统,其特征在于:5. The laser ablation system according to claim 1, wherein:所述第一光波导设置为多根,多根所述第一光波导的远端端面位于同一平面内。The first optical waveguides are arranged in multiples, and the distal end faces of the multiple first optical waveguides are located in the same plane.6.根据权利要求5所述的激光消蚀系统,其特征在于:6. The laser ablation system according to claim 5, wherein:多根所述第一光波导的远端端面所确定的区域与所述导管的轴线偏心设置。The regions defined by the distal end faces of the plurality of first optical waveguides are arranged eccentrically from the axis of the conduit.7.根据权利要求5所述的激光消蚀系统,其特征在于:7. The laser ablation system according to claim 5, wherein:多根第一光波导的远端端面所确定的区域均与所述导管的轴线同轴设置。The regions defined by the distal end faces of the plurality of first optical waveguides are all arranged coaxially with the axis of the conduit.8.根据权利要求7所述的激光消蚀系统,其特征在于:8. The laser ablation system according to claim 7, wherein:所述第一光学元件组的远端端面与所述导管的轴线同轴设置。The distal end face of the first optical element group is coaxial with the axis of the catheter.9.根据权利要求1-8中任一项所述的激光消蚀系统,其特征在于:9. The laser ablation system according to any one of claims 1-8, wherein:所述OCT成像装置还包括传导光纤、准直器、振镜扫描仪和第二光学元件组,所述第一光束依次经过所述传导光纤、准直器、振镜扫描仪和第二光学元件组后传播至所述第二光波导。The OCT imaging device further comprises a conducting fiber, a collimator, a galvanometer scanner and a second optical element group, and the first light beam passes through the conducting fiber, the collimator, the galvanometer scanner and the second optical element in sequence After the group is propagated to the second optical waveguide.10.根据权利要求1所述的激光消蚀系统,其特征在于:10. The laser ablation system of claim 1, wherein:所述导管的外周壁设有显影部。The outer peripheral wall of the conduit is provided with a developing portion.
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
CN113729937A (en)*2021-10-082021-12-03南京沃福曼医疗科技有限公司Laser ablation system integrating OCT (optical coherence tomography) evaluation
CN114431955A (en)*2022-02-142022-05-06清华大学Ultrafast laser galvanometer scanning coupling method
CN114469334A (en)*2021-07-052022-05-13深圳市中科微光医疗器械技术有限公司Laser output device, method, terminal and storage medium
CN114469337A (en)*2021-07-052022-05-13深圳市中科微光医疗器械技术有限公司Ablation catheter assembly, laser ablation system and method
CN114469335A (en)*2021-07-052022-05-13深圳市中科微光医疗器械技术有限公司Laser ablation system and laser output method
CN114469333A (en)*2021-07-052022-05-13深圳市中科微光医疗器械技术有限公司Ablation catheter, laser ablation system and intravascular laser plaque ablation method
CN115919453A (en)*2022-12-302023-04-07深圳市中科融光医疗科技有限公司 Imageable laser ablation catheter and method of use thereof
CN118787442A (en)*2024-09-132024-10-18文皓(南京)科技有限责任公司 Laser ablation catheter end bending control method and device

Citations (21)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EP0296982A1 (en)*1987-06-251988-12-28Hanna KhalilDevice for correcting the shape of an object by laser treatment
DE102006022197B3 (en)*2006-05-122008-01-10Carl Zeiss Meditec AgCoherent radiation source e.g. laser, for optical coherence tomography, has luminescence material layer for radiation conversion arranged in cross section area of focused output radiation
CN101313839A (en)*2008-06-282008-12-03徐州雷奥医疗设备有限公司Rotatable soft-body endoscope
CN101636668A (en)*2006-11-282010-01-27总线公司The Apparatus and method for that is used for ultrasonic imaging and laser ablation
CN101653376A (en)*2008-08-182010-02-24富士胶片株式会社Laser treatment apparatus
CN101842718A (en)*2007-10-292010-09-22皇家飞利浦电子股份有限公司Systems and methods for ultrasound assembly including multiple imaging transducer arrays
CN102274018A (en)*2011-05-232011-12-14成正辉Fast-switching and mapping catheter, and preparation method and application method thereof
CN102379680A (en)*2011-08-252012-03-21苏州新视野光电技术有限公司Optical coherence tomographic imaging system
CN102885648A (en)*2012-08-292013-01-23中国人民解放军第三军医大学第一附属医院Sympathetic nerve denervation ablation catheter system for kidneys
CN103381088A (en)*2013-08-022013-11-06广州医学院第一附属医院Fiber endoscope
CN106794043A (en)*2014-05-182017-05-31爱克斯莫医疗有限公司 A system for tissue ablation using pulsed lasers
CN107049483A (en)*2017-05-162017-08-18张鲲Laser surgery equipment for vascular surgery
US20170357997A1 (en)*2012-09-162017-12-14American Express Travel Related Services Company, Inc.Transaction triggered rewards
CN107961072A (en)*2017-11-222018-04-27天津科技大学A kind of device being purged by laser to intravascular fatty tamper
CN108245126A (en)*2018-03-262018-07-06精微视达医疗科技(武汉)有限公司It is a kind of can be with the sonde-type co-focusing micro-endoscope of laser ablation
CN108294821A (en)*2018-01-242018-07-20深圳市凯思特医疗科技股份有限公司Laser imaging targeting ablation conduit
CN109691971A (en)*2018-12-292019-04-30佛山科学技术学院The optical coherence tomography system of anterior ocular segment tissue dynamic parameter fast imaging
WO2019112199A1 (en)*2017-12-052019-06-13주식회사 루트로닉Microlens array, and laser beam hand piece and therapeutic laser device comprising same
CN110051432A (en)*2019-05-272019-07-26北京航空航天大学A method of laser thrombolysis in the blood vessel is realized under optical coherence tomography guidance
WO2019145484A1 (en)*2018-01-252019-08-01KeranovaApparatus for cutting a human or animal tissue comprising an optical coupler
CN210408379U (en)*2019-04-082020-04-28广东唯仁医疗科技有限公司Anterior segment OCT imaging device

Patent Citations (21)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EP0296982A1 (en)*1987-06-251988-12-28Hanna KhalilDevice for correcting the shape of an object by laser treatment
DE102006022197B3 (en)*2006-05-122008-01-10Carl Zeiss Meditec AgCoherent radiation source e.g. laser, for optical coherence tomography, has luminescence material layer for radiation conversion arranged in cross section area of focused output radiation
CN101636668A (en)*2006-11-282010-01-27总线公司The Apparatus and method for that is used for ultrasonic imaging and laser ablation
CN101842718A (en)*2007-10-292010-09-22皇家飞利浦电子股份有限公司Systems and methods for ultrasound assembly including multiple imaging transducer arrays
CN101313839A (en)*2008-06-282008-12-03徐州雷奥医疗设备有限公司Rotatable soft-body endoscope
CN101653376A (en)*2008-08-182010-02-24富士胶片株式会社Laser treatment apparatus
CN102274018A (en)*2011-05-232011-12-14成正辉Fast-switching and mapping catheter, and preparation method and application method thereof
CN102379680A (en)*2011-08-252012-03-21苏州新视野光电技术有限公司Optical coherence tomographic imaging system
CN102885648A (en)*2012-08-292013-01-23中国人民解放军第三军医大学第一附属医院Sympathetic nerve denervation ablation catheter system for kidneys
US20170357997A1 (en)*2012-09-162017-12-14American Express Travel Related Services Company, Inc.Transaction triggered rewards
CN103381088A (en)*2013-08-022013-11-06广州医学院第一附属医院Fiber endoscope
CN106794043A (en)*2014-05-182017-05-31爱克斯莫医疗有限公司 A system for tissue ablation using pulsed lasers
CN107049483A (en)*2017-05-162017-08-18张鲲Laser surgery equipment for vascular surgery
CN107961072A (en)*2017-11-222018-04-27天津科技大学A kind of device being purged by laser to intravascular fatty tamper
WO2019112199A1 (en)*2017-12-052019-06-13주식회사 루트로닉Microlens array, and laser beam hand piece and therapeutic laser device comprising same
CN108294821A (en)*2018-01-242018-07-20深圳市凯思特医疗科技股份有限公司Laser imaging targeting ablation conduit
WO2019145484A1 (en)*2018-01-252019-08-01KeranovaApparatus for cutting a human or animal tissue comprising an optical coupler
CN108245126A (en)*2018-03-262018-07-06精微视达医疗科技(武汉)有限公司It is a kind of can be with the sonde-type co-focusing micro-endoscope of laser ablation
CN109691971A (en)*2018-12-292019-04-30佛山科学技术学院The optical coherence tomography system of anterior ocular segment tissue dynamic parameter fast imaging
CN210408379U (en)*2019-04-082020-04-28广东唯仁医疗科技有限公司Anterior segment OCT imaging device
CN110051432A (en)*2019-05-272019-07-26北京航空航天大学A method of laser thrombolysis in the blood vessel is realized under optical coherence tomography guidance

Cited By (11)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
CN114469334A (en)*2021-07-052022-05-13深圳市中科微光医疗器械技术有限公司Laser output device, method, terminal and storage medium
CN114469337A (en)*2021-07-052022-05-13深圳市中科微光医疗器械技术有限公司Ablation catheter assembly, laser ablation system and method
CN114469335A (en)*2021-07-052022-05-13深圳市中科微光医疗器械技术有限公司Laser ablation system and laser output method
CN114469333A (en)*2021-07-052022-05-13深圳市中科微光医疗器械技术有限公司Ablation catheter, laser ablation system and intravascular laser plaque ablation method
CN114469333B (en)*2021-07-052024-02-20深圳市中科融光医疗科技有限公司Ablation catheter, laser ablation system and intravascular laser plaque ablation method
CN114469335B (en)*2021-07-052024-02-20深圳市中科融光医疗科技有限公司Laser ablation system
CN114469337B (en)*2021-07-052024-06-04深圳市中科融光医疗科技有限公司Ablation catheter assembly, laser ablation system and method
CN113729937A (en)*2021-10-082021-12-03南京沃福曼医疗科技有限公司Laser ablation system integrating OCT (optical coherence tomography) evaluation
CN114431955A (en)*2022-02-142022-05-06清华大学Ultrafast laser galvanometer scanning coupling method
CN115919453A (en)*2022-12-302023-04-07深圳市中科融光医疗科技有限公司 Imageable laser ablation catheter and method of use thereof
CN118787442A (en)*2024-09-132024-10-18文皓(南京)科技有限责任公司 Laser ablation catheter end bending control method and device

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