CN112755396A - Transcranial magnetic stimulation system - Google Patents
Transcranial magnetic stimulation systemDownload PDFInfo
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- CN112755396A CN112755396ACN202110081658.XACN202110081658ACN112755396ACN 112755396 ACN112755396 ACN 112755396ACN 202110081658 ACN202110081658 ACN 202110081658ACN 112755396 ACN112755396 ACN 112755396A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/004—Magnetotherapy specially adapted for a specific therapy
- A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
- H02J7/00—Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
- H02J7/0068—Battery or charger load switching, e.g. concurrent charging and load supply
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
- H02J7/00—Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
- H02J7/34—Parallel operation in networks using both storage and other DC sources, e.g. providing buffering
- H02J7/345—Parallel operation in networks using both storage and other DC sources, e.g. providing buffering using capacitors as storage or buffering devices
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02B—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
- Y02B70/00—Technologies for an efficient end-user side electric power management and consumption
- Y02B70/10—Technologies improving the efficiency by using switched-mode power supplies [SMPS], i.e. efficient power electronics conversion e.g. power factor correction or reduction of losses in power supplies or efficient standby modes
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Abstract
Description
[ technical field ] A method for producing a semiconductor device
The invention relates to the technical field of transcranial magnetic stimulation, in particular to a transcranial magnetic stimulation system.
[ background of the invention ]
Paired transcranial magnetic stimulation (pTMS)), two pulses are output in pairs (paired mode) each time the lock is locked, the interval of the two pulses of the pTMS can be adjusted from 0-50ms, the two pulses can be output to the same stimulation coil, the same part can be stimulated in pairs, the two stimulation coils can also be respectively output, different parts can be stimulated synchronously or in pairs and sequentially, the first stimulation is Conditioned Stimulation (CS), and the second stimulation is experimental stimulation (TS).
Paired stimulation is mainly used for detecting excitability and inhibitivity of cortical nerves and conduction and functional integrity between the cortices, can detect and utilize plasticity of cortical nerve functions and interaction of nerve cells in the cortex and between the cortex to modulate target cortical nerve functions, artificially interfere and regulate and control stimulated nerve functions, and achieves the therapeutic effect of LTP (long-term potentiation)/LTD (long-term inhibition).
The paired stimulation equipment is special, and two sets of charging and discharging systems, two sets of silicon controlled switches and two energy storage capacitors are needed to respectively charge the capacitors, and then the paired stimulation is carried out in turn according to the set time sequence. If the paired stimulation is operated continuously, called repeated paired stimulation (rpTMS), a new type of neuromodulation therapy, varying the intensity, interval and gap between pairs of paired stimulation, long-term modulation of cortical excitability can be achieved. But in the market, the single magnetic stimulation or the paired magnetic stimulation interval is too long, the time can not be 0-50ms required by clinical significance, the real application scene of the paired magnetic stimulation can not be achieved,
in view of the above, there is a need for a new transcranial magnetic stimulation system that overcomes the above-mentioned deficiencies.
[ summary of the invention ]
The invention aims to provide a transcranial magnetic stimulation system, which can respectively utilize a first electronic switch group to control a first energy storage unit and a second electronic switch group to control a second energy storage unit to charge and discharge a magnetic stimulation coil in order, so that the magnetic stimulation coil can release paired magnetic fields at intervals of 0-50ms, and the ordering of the magnetic stimulation coil to release the magnetic fields is ensured to meet the clinical application of magnetic stimulation.
In order to achieve the above object, the present invention provides a transcranial magnetic stimulation system, comprising acontrol device 1 and acooling device 2; thecontrol device 1 comprises a first electronic switch group 100, a secondelectronic switch group 200, acomputer 11, aprocessor 12, anacquisition module 13, a human-computer interaction module 14, a controlsignal generation module 15, a firstpower factor corrector 16, afirst charging module 17, a firstenergy storage element 18, a secondpower factor corrector 160, asecond charging module 170, a secondenergy storage element 180 and amagnetic stimulation coil 19;
the first electronic switch group 100 comprises a first electronic switch 101 and a secondelectronic switch 102, the secondelectronic switch group 200 comprises a thirdelectronic switch 201 and a fourthelectronic switch 202, thecomputer 11 is in communication connection with theprocessor 12, and theprocessor 12 is in communication connection with theacquisition module 13, the human-computer interaction module 14, the controlsignal generation module 15 and thecooling device 2;
the firstpower factor corrector 16, thefirst charging module 17 and the firstenergy storage element 18 are electrically connected in sequence, the positive electrode of the firstenergy storage element 18 is electrically connected with the positive electrode of the first electronic switch 101 of the first electronic switch group 100 and the negative electrode of the secondelectronic switch 102, the negative electrode of the first electronic switch 101 of the first electronic switch group 100 and the positive electrode of the secondelectronic switch 102 are electrically connected with the first end of themagnetic stimulation coil 19, and the control electrode of the first electronic switch 101 and the control electrode of the secondelectronic switch 102 of the first electronic switch group 10 are both in communication connection with the controlsignal generation module 15;
the secondpower factor corrector 160, thesecond charging module 170, and the secondenergy storage element 180 are electrically connected in sequence, and the positive electrode of the secondenergy storage element 180 is electrically connected to the second end of themagnetic stimulation coil 19, the first end of themagnetic stimulation coil 19 is electrically connected to the positive electrode of the thirdelectronic switch 201 and the negative electrode of the fourthelectronic switch 202 of the secondelectronic switch group 200, the negative electrode of the thirdelectronic switch 201 and the positive electrode of the fourthelectronic switch 202 of the secondelectronic switch group 200 are electrically connected to the secondenergy storage element 180, the control electrode of the thirdelectronic switch 201 and the control electrode of the fourthelectronic switch 202 of the secondelectronic switch group 200 are both in communication connection with the controlsignal generation module 15, and the second end of themagnetic stimulation coil 19 is electrically connected to the negative electrode of the firstenergy storage element 18.
Preferably, theacquisition module 13 includes anacquisition unit 130, apreamplifier 131, anotch filter 132, a program-controlledamplifier 133, a band-pass filter 134, an a/D converter 135, a firstsingle chip microcomputer 136, adigital signal processor 137, a first isolation transceiver, and a first surge protector; theacquisition unit 130, thepreamplifier 131, thenotch filter 132, the program-controlledamplifier 133, the band-pass filter 134, the a/D converter 135, the firstsingle chip microcomputer 136 and thedigital signal processor 137 are electrically connected in sequence, the firstsingle chip microcomputer 136 is electrically connected with the program-controlledamplifier 133, the first isolation transceiver is electrically connected with the first surge protector, and the first surge protector is electrically connected between the program-controlledamplifier 133 and the firstsingle chip microcomputer 136.
Preferably, thecooling device 2 includes a second isolation transceiver, a second surge protector, a secondsingle chip microcomputer 20, anisolator 21, a water pump 22, anair pump 23, awater tank 24, aflow sensor 25 and a temperature sensor 26; transceiver, second surge protector,second singlechip 20,isolator 21 electric connection in proper order are kept apart to the second, water pump 22 andair pump 23 all withisolator 21 electric connection, just water pump 22 andair pump 23 all withwater tank 24 is connected,cooling device 2's water tank 24 withmagnetic stimulation coil 19 is connected,flow sensor 25 and temperature sensor 26 all withsecond singlechip 20 electric connection, the coolant liquid has been accommodated in thewater tank 24.
Preferably, thecooling device 2 further comprises afan 27, and thefan 27 is disposed adjacent to the water pump 22 and electrically connected to theisolator 21.
Preferably, thecooling device 2 further comprises a hydraulic pressure sensor 28 and a liquid level sensor 29; hydraulic pressure sensor 28 withsecond singlechip 20 electric connection, level sensor 29 withsecond singlechip 20 electric connection and being located in thewater tank 24, hydraulic pressure sensor 28 is used for detecting cooling liquid pressure and uploads the hydraulic information that detects tosecond singlechip 20, level sensor 28 is used for detecting the liquid level in the water tank and uploads the liquid level information that detects tosecond singlechip 20,second singlechip 20 passes through liquid level information andhydraulic information processor 12 uploads tocomputer 11,computer 11's touch screen shows liquid level information and hydraulic information.
Preferably, the human-computer interaction module 14 includes akey matrix 141, a thirdsingle chip microcomputer 142, asound generator 143, a third isolation transceiver and a third surge protector, thekey matrix 141, thesound generator 143, the third isolation transceiver and the third surge protector are all electrically connected to the thirdsingle chip microcomputer 142, and the thirdsingle chip microcomputer 142 is in communication connection with theprocessor 12.
Preferably, the human-computer interaction module 14 further includes abreathing lamp 144 and aprogrammable driver 145, and theprogrammable driver 145 is electrically connected between the thirdsingle chip microcomputer 142 and thebreathing lamp 144.
Preferably, the controlsignal generating module 15 includes adelay unit 150, a fourth isolation transceiver, a fourth surge protector, a fourthsingle chip microcomputer 151 and aphotoelectric isolation chip 152, and thedelay unit 150, the fourth isolation transceiver, the fourth surge protector and thephotoelectric isolation chip 152 are all electrically connected to the fourthsingle chip microcomputer 151.
Compared with the prior art, the transcranial magnetic stimulation system provided by the invention has the beneficial effects that: the first electronic switch group can be respectively utilized to control the first energy storage unit and the second electronic switch group to control the second energy storage unit to orderly charge and discharge the magnetic stimulation coil, so that the magnetic stimulation coil can release paired magnetic fields at intervals of 0-50ms, and the orderliness of the magnetic stimulation coil to release the magnetic fields is ensured to meet the clinical application of magnetic stimulation.
[ description of the drawings ]
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
Fig. 1 is a schematic block diagram of a transcranial magnetic stimulation system provided by the present invention.
Fig. 2 is a schematic block diagram of an acquisition module of a transcranial magnetic stimulation system provided by the present invention.
Fig. 3 is a functional block diagram of a cooling device of a transcranial magnetic stimulation system provided by the present invention.
Fig. 4 is a schematic block diagram of a human-computer interaction module of the transcranial magnetic stimulation system provided by the invention.
Fig. 5 is a functional block diagram of a control signal generation module of a transcranial magnetic stimulation system provided by the present invention.
Fig. 6 is a waveform diagram of a magnetic stimulation coil of a transcranial magnetic stimulation system provided by the present invention.
Fig. 7 is a waveform diagram of a magnetic stimulation coil of a transcranial magnetic stimulation system provided by the present invention after a delay interval.
[ detailed description ] embodiments
In order to make the objects, technical solutions and advantageous effects of the present invention more clearly apparent, the present invention is further described in detail below with reference to the accompanying drawings and the detailed description. It should be understood that the detailed description and specific examples, while indicating the preferred embodiment of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.
It will be understood that the terms "upper," "lower," "front," "rear," "left," "right," "top," "bottom," "inner," "outer," and the like are used in the orientation or positional relationship indicated in the drawings for ease of description and simplicity of description, and do not indicate or imply that the referenced devices or elements must be in a particular orientation, constructed and operated in a particular orientation, and are therefore not to be considered limiting.
It is also noted that, unless expressly stated or limited otherwise, the terms "mounted," "connected," "secured," "disposed," and the like are intended to be inclusive and mean, for example, that they may be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. To those of ordinary skill in the art, the above terms may be specifically defined in the present invention according to the specific circumstances.
Furthermore, the terms "first", "second", and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first", "second", may explicitly or implicitly include one or more of that feature. Further, the meaning of "a plurality" or "a plurality" means two or more unless specifically limited otherwise.
Referring to fig. 1, the present invention provides a transcranial magnetic stimulation system, which includes acontrol device 1 and acooling device 2; thecontrol device 1 comprises a first electronic switch group 100, a secondelectronic switch group 200, acomputer 11, aprocessor 12, anacquisition module 13, a human-computer interaction module 14, a controlsignal generation module 15, a firstpower factor corrector 16, afirst charging module 17, a firstenergy storage element 18, a secondpower factor corrector 160, asecond charging module 170, a secondenergy storage element 180 and amagnetic stimulation coil 19;
the first electronic switch group 100 comprises a first electronic switch 101 and a secondelectronic switch 102, the secondelectronic switch group 200 comprises a thirdelectronic switch 201 and a fourthelectronic switch 202, thecomputer 11 is in communication connection with theprocessor 12, and theprocessor 12 is in communication connection with theacquisition module 13, the human-computer interaction module 14, the controlsignal generation module 15 and thecooling device 2;
the firstpower factor corrector 16, thefirst charging module 17 and the firstenergy storage element 18 are electrically connected in sequence, the positive electrode of the firstenergy storage element 18 is electrically connected with the positive electrode of the first electronic switch 101 of the first electronic switch group 100 and the negative electrode of the secondelectronic switch 102, the negative electrode of the first electronic switch 101 of the first electronic switch group 100 and the positive electrode of the secondelectronic switch 102 are electrically connected with the first end of themagnetic stimulation coil 19, and the control electrode of the first electronic switch 101 and the control electrode of the secondelectronic switch 102 of the first electronic switch group 10 are both in communication connection with the controlsignal generation module 15;
the secondpower factor corrector 160, thesecond charging module 170, and the secondenergy storage element 180 are electrically connected in sequence, and the positive electrode of the secondenergy storage element 180 is electrically connected to the second end of themagnetic stimulation coil 19, the first end of themagnetic stimulation coil 19 is electrically connected to the positive electrode of the thirdelectronic switch 201 and the negative electrode of the fourthelectronic switch 202 of the secondelectronic switch group 200, the negative electrode of the thirdelectronic switch 201 and the positive electrode of the fourthelectronic switch 202 of the secondelectronic switch group 200 are electrically connected to the secondenergy storage element 180, the control electrode of the thirdelectronic switch 201 and the control electrode of the fourthelectronic switch 202 of the secondelectronic switch group 200 are both in communication connection with the controlsignal generation module 15, and the second end of themagnetic stimulation coil 19 is electrically connected to the negative electrode of the firstenergy storage element 18.
In the present embodiment, the first electronic switch 101, the secondelectronic switch 102, the thirdelectronic switch 201, and the fourthelectronic switch 202 may be any one of a one-way thyristor, a triode thyristor, an IGBT (Insulated Gate Bipolar Transistor), and a MOS Transistor.
Referring to fig. 2 to 7, theprocessor 12 receives an instruction from thecomputer 11, and sends a received instruction signal to theacquisition module 13, the human-computer interaction module 14, the controlsignal generation module 15, and thecooling device 2;
the collectingmodule 13 is used for collecting the electromyographic signals of the human body, amplifying, filtering and A/D converting the collected electromyographic signals of the human body to generate electrophysiological signals, sending the electrophysiological signals to theprocessor 12, theprocessor 12 transmitting the received electromyographic signals to thecomputer 11,
thepfc 16 converts AC power of AC220V into DC power of DC360V, thecharging module 17 converts a DC voltage signal into a continuously output high-voltage pulse voltage signal to charge the firstenergy storage element 18, the controlsignal generating module 15 receives an experimental pulse stimulation command signal from theprocessor 12 and transmits the high-voltage pulse voltage signal to thecharging module 17 to charge the first energy storage element 18 (capacitor), and the controlsignal generating module 15 may further receive a single stimulation command signal from theprocessor 12 to make the first electronic switch 101 of the first electronic switch group 100 conduct and the secondelectronic switch 102 not conduct, so that the energy stored in the first energy storage element 18 (capacitor) is instantaneously released to themagnetic stimulation coil 19, and themagnetic stimulation coil 19 generates a forward magnetic field; when the first electronic switch 101 of the first electronic switch group 100 is not turned on and the secondelectronic switch 102 is turned on, the stored energy on the first energy storage element 18 (capacitor) is instantaneously released to themagnetic stimulation coil 19 through the secondelectronic switch 102, and themagnetic stimulation coil 19 generates a reverse magnetic field;
the controlsignal generating module 15 may further receive a single stimulation instruction signal from theprocessor 12, so that when the thirdelectronic switch 201 of the secondelectronic switch group 200 is turned on and the fourthelectronic switch 202 is not turned on, the stored energy in the second energy storage element 180 (capacitor) is instantaneously released to themagnetic stimulation coil 19, and themagnetic stimulation coil 19 generates a forward magnetic field; when the thirdelectronic switch 201 of the secondelectronic switch group 200 is not turned on and the fourthelectronic switch 202 is turned on, the stored energy in the second energy storage element 180 (capacitor) is instantaneously released to themagnetic stimulation coil 19 through the fourthelectronic switch 202, and themagnetic stimulation coil 19 generates a reverse magnetic field;
after the signalcontrol production module 15 receives the instruction of adjusting the magnetic stimulation intensity, the interface display intensity percentage of the touch screen of thecomputer 11 is converted into linear direct current of 0-3.3V and output to thefirst charging module 17 and thesecond charging module 170;
thecooling device 2 is used for adjusting the temperature of themagnetic stimulation coil 19, and the touch screen of thecomputer 11 displays the waveform of the magnetic field of themagnetic stimulation coil 19.
Further, theacquisition module 13 includes anacquisition unit 130, apreamplifier 131, anotch filter 132, a program-controlledamplifier 133, a band-pass filter 134, an a/D converter 135, a first single-chip microcomputer 136, adigital signal processor 137, a first isolation transceiver, and a first surge protector; theacquisition unit 130, thepreamplifier 131, thenotch filter 132, the program-controlledamplifier 133, the band-pass filter 134, the a/D converter 135, the firstsingle chip microcomputer 136 and thedigital signal processor 137 are electrically connected in sequence, the firstsingle chip microcomputer 136 is electrically connected with the program-controlledamplifier 133, the first isolation transceiver is electrically connected with the first surge protector, the first surge protector is electrically connected between the program-controlledamplifier 133 and the firstsingle chip microcomputer 136, and the first isolation transceiver and the first surge protector are integrated together.
In this embodiment, thepreamplifier 131 has the functions of isolation and buffering, does not change the signal strength, receives the signal through the input impedance, and sends the signal out in the form of impedance output; thenotch filter 132 is used for filtering a 50Hz power frequency signal in the alternating current; theprogram control amplifier 133 adopts a numerical control programmable gain instrument amplifier of TI company, which can realize the program control gain of 1-8000, the A/D converter 135 adopts a high-speed and high-precision 24-bit analog-to-digital converter AD9208 of ADI company, which is used for converting the signal output by the band-pass filter 134 into a digital signal and then transmitting the digital signal to thedigital signal processor 137, thedigital signal processor 137 receives the converted signal and then transmits the signal to thecomputer 11, and the model of thefirst singlechip 136 isLPC11C 14; the model of the first isolation transceiver is ADM 3058E; the model of the first surge protector is TVS 0701.
When thecomputer 11 of the transcranial magnetic stimulation system outputs a magnetic stimulation command signal, theacquisition unit 130 of theacquisition module 13 acquires a waveform after receiving the command signal for acquiring the waveform, thepreamplifier 131 receives the command signal for acquiring the waveform and amplifies the command signal for acquiring the waveform, thenotch filter 132 receives the amplified command signal for acquiring the waveform and filters the command signal for acquiring the waveform, the program-controlledamplifier 133 receives the filtered command signal for acquiring the waveform and program-controlled amplifies the command signal for acquiring the waveform, the band-pass filter 134 receives the command signal for acquiring the waveform amplified by the program-controlledamplifier 133 and filters the command signal for acquiring the waveform, the a/D converter 135 converts the command signal for acquiring the waveform filtered by the band-pass filter 134 into a digital quantity and transmits the digital quantity to the firstsingle chip microcomputer 136, the firstsingle chip microcomputer 136 sends an instruction to thedigital signal processor 137, so that thedigital signal processor 137 starts to collect digital quantity received by the firstsingle chip microcomputer 136 and sends the digital quantity to theprocessor 12, theprocessor 12 sends the digital quantity to thecomputer 11, and the touch screen of thecomputer 11 displays the waveform of the magnetic field.
Further, the controlsignal generating module 15 further includes adelay unit 150, where thedelay unit 150 is communicatively connected to the control electrode of the first electronic switch 101 and the control electrode of the secondelectronic switch 102 of the first electronic switch group 100, and thedelay unit 150 is communicatively connected to the control electrode of the thirdelectronic switch 201 and the control electrode of the fourthelectronic switch 202 of the secondelectronic switch group 200.
In this way, when the controlsignal generating module 15 can also receive the delayed magnetic stimulation instruction signal of theprocessor 12 to make the thirdelectronic switch 201 of the secondelectronic switch group 200 turned on and the fourthelectronic switch 202 turned off, the stored energy in the secondenergy storage element 180 is instantaneously released to themagnetic stimulation coil 19, and themagnetic stimulation coil 19 generates a forward magnetic field; the delay unit of the control signal generatingmodule 15 delays 0-50ms to make the thirdelectronic switch 201 of the secondelectronic switch group 200 not be turned on and the fourthelectronic switch 202 be turned on, so that the stored energy in the secondenergy storage element 180 is instantaneously released to themagnetic stimulation coil 19 through the fourthelectronic switch 202, and themagnetic stimulation coil 19 generates a reverse magnetic field.
Further, thecooling device 2 comprises a second isolation transceiver, a second surge protector, a secondsingle chip microcomputer 20, anisolator 21, a water pump 22, anair pump 23, awater tank 24, aflow sensor 25 and a temperature sensor 26; transceiver, second surge protector,second singlechip 20,isolator 21 electric connection in proper order are kept apart to the second, water pump 22 andair pump 23 all withisolator 21 electric connection, just water pump 22 andair pump 23 all withwater tank 24 is connected,cooling device 2'swater tank 24 withmagnetic stimulation coil 19 is connected,flow sensor 25 and temperature sensor 26 all withsecond singlechip 20 electric connection, the coolant liquid has been accommodated in thewater tank 24. In this embodiment, the second isolating transceiver has a model of ADM 3058E; the model of the second surge protector is TVS 0701; the model of thesecond singlechip 20 is STM32F103C 6; theisolator 21 IS model IS480P and IS used for isolating interference when the water pump 22 and theair pump 23 rotate.
Further, thecooling device 2 further includes afan 27, and thefan 27 is disposed adjacent to the water pump 22 and electrically connected to theisolator 21.
When thecomputer 11 of the transcranial magnetic stimulation system outputs a magnetic stimulation instruction signal, an operator issues an instruction for starting thefan 27 and the water pump 22 through thecomputer 11, the secondsingle chip microcomputer 20 of thecooling device 2 starts thefan 27 and the water pump 22 after receiving the instruction, the cooling liquid in the water tank 26 enters the water pump 22 under the action of the water pump 22, then the cooling liquid enters themagnetic stimulation coil 19 to reduce the temperature of themagnetic stimulation coil 19 and flows back to thewater tank 24 through theflow sensor 25 and the temperature sensor 26, theflow sensor 25 and the temperature sensor 26 respectively detect the flow and the temperature of the cooling liquid and upload the detected flow information and temperature information to the secondsingle chip microcomputer 20, and then the secondsingle chip microcomputer 20 uploads the flow information and temperature information to thecomputer 11 through theprocessor 12 to monitor the circulating flowing state of the cooling liquid, the touch screen of thecomputer 11 displays flow information and temperature information.
When thewater pump 24 is started and theflow sensor 25 cannot detect the flow of the cooling liquid, an operator can give an instruction to stop the operation of the water pump 22 and stop the magnetic stimulation of themagnetic stimulation coil 19 through thecomputer 11; when the transcranial magnetic stimulation system needs to replace themagnetic stimulation coil 19 or overhaul, an operator can issue a command for discharging cooling liquid through thecomputer 11, at the moment, theair pump 23 is started to discharge the cooling liquid remained in themagnetic stimulation coil 19 into the water return tank 26, and the rotating speeds of the water pump 22, thefan 27 and theair pump 23 can be adjusted through the secondsingle chip microcomputer 20.
Further, thecooling device 2 further comprises a hydraulic pressure sensor 28 and a liquid level sensor 29; hydraulic pressure sensor 28 withsecond singlechip 20 electric connection, level sensor 29 withsecond singlechip 20 electric connection and being located in thewater tank 24, hydraulic pressure sensor 28 is used for detecting cooling liquid pressure and uploads the hydraulic information that detects tosecond singlechip 20, level sensor 28 is used for detecting the liquid level in the water tank and uploads the liquid level information that detects tosecond singlechip 20, subsequentlysecond singlechip 20 passes through liquid level information and hydraulic information treater 12 and uploads tocomputer 11,computer 11's touch screen shows liquid level information and hydraulic information.
Further, the human-computer interaction module 14 includes akey matrix 141, a thirdsingle chip microcomputer 142, asound generator 143, a third isolation transceiver and a third surge protector, thekey matrix 141, thesound generator 143, the third isolation transceiver and the third surge protector are all electrically connected to the thirdsingle chip microcomputer 142, the thirdsingle chip microcomputer 142 is in communication connection with theprocessor 12, and the third isolation transceiver and the third surge protector are integrated together. In this embodiment, the model of the thirdsingle chip microcomputer 142 is LPC11C 14; the model of the third isolation transceiver is ADM3058E, and the model of the third surge protector is TVS 0701.
Further, the human-computer interaction module 14 further includes abreathing lamp 144 and aprogrammable driver 145, and theprogrammable driver 145 is electrically connected between the thirdsingle chip microcomputer 142 and thebreathing lamp 144. In this embodiment, theprogrammable driver 145 has a model ADP8863, and is used for adjusting the lighting effect of thebreathing lamp 144.
When an interface of a touch screen of thecomputer 11 is clicked or a key of the operationkey matrix 141 is operated to trigger themagnetic stimulation coil 19 to generate a magnetic field, thecomputer 11 sends a blinking instruction to thebreathing lamp 144 of the human-computer interaction module 14 through theprocessor 12, and at this time, an operator can hear a click sound emitted by the sounder 143, and the brightness of the breathing lamp 146 changes; when thecomputer 11 issues an instruction for adjusting the magnetic stimulation intensity to the controlsignal generation module 15 through theprocessor 12, the stored energy in the firstenergy storage element 18 or the secondenergy storage element 180 correspondingly changes the voltage released to themagnetic stimulation coil 19, so as to adjust the magnetic field intensity of themagnetic stimulation coil 19.
Further, the controlsignal generating module 15 further includes a fourth isolation transceiver, a fourth surge protector, a fourthsingle chip microcomputer 151 and aphotoelectric isolation chip 152, thedelay unit 150, the fourth isolation transceiver, the fourth surge protector and thephotoelectric isolation chip 152 are all electrically connected to the fourthsingle chip microcomputer 151, and the fourth isolation transceiver and the fourth surge protector are integrated together. In this embodiment, the model of the fourthsingle chip microcomputer 151 is STM32F103RF, the model of the fourth isolation transceiver is ADM3058E, the model of the fourth surge protector is TVS0701, and the model of theoptoelectronic isolation chip 152 is TLP 521-4.
When thefourth isolation transceiver 151 of the controlsignal generation module 15 receives the instruction of adjusting the magnetic stimulation intensity, and transmits a high-voltage pulse voltage signal to the chargingmodule 17 to charge the first energy storage element 18 (capacitor), the interface display intensity percentage of the touch screen of thecomputer 11 is converted into a linear 0-3.3V dc quantity, and the dc quantity is output to the chargingmodule 17;
when the controlsignal generating module 15 can also receive a delayed magnetic stimulation instruction signal of theprocessor 12, so that the thirdelectronic switch 201 of the secondelectronic switch group 200 is turned on and the fourthelectronic switch 202 is not turned on, the stored energy in the secondenergy storage element 180 is instantaneously released to themagnetic stimulation coil 19, and themagnetic stimulation coil 19 generates a forward magnetic field; when the thirdsingle chip microcomputer 142 of the controlsignal generating module 15 delays by 0-50ms through thedelay unit 150 to make the thirdelectronic switch 201 of the second electronic switch group not be turned on and the fourthelectronic switch 202 turned on, the stored energy in the secondenergy storage element 180 is instantaneously released to themagnetic stimulation coil 19 through the fourthelectronic switch 202, and themagnetic stimulation coil 19 generates a reverse magnetic field;
theprocessor 12 receives the feedback signal (the magnetic field waveform state signal and the energy storage state signal) of the fourth isolator and uploads the feedback signal to thecomputer 11, and a touch screen of thecomputer 11 displays the waveform of the magnetic field of the magnetic stimulation coil, the waveform of the human body electromyogram signal, the energy storage state of the firstenergy storage element 18 and the energy storage state of the secondenergy storage element 180.
The invention is not limited solely to that described in the specification and embodiments, and additional advantages and modifications will readily occur to those skilled in the art, so that the invention is not limited to the specific details, representative apparatus, and examples shown and described herein, without departing from the spirit and scope of the general concept as defined by the appended claims and their equivalents.
Claims (8)
1. A transcranial magnetic stimulation system, comprising a control device (1) and a cooling device (2); the control device (1) comprises a first electronic switch group (100), a second electronic switch group (200), a computer (11), a processor (12), an acquisition module (13), a man-machine interaction module (14), a control signal generation module (15), a first power factor corrector (16), a first charging module (17), a first energy storage element (18), a second power factor corrector (160), a second charging module (170), a second energy storage element (180) and a magnetic stimulation coil (19);
the system is characterized in that the first electronic switch group (100) comprises a first electronic switch (101) and a second electronic switch (102), the second electronic switch group (200) comprises a third electronic switch (201) and a fourth electronic switch (202), the computer (11) is in communication connection with a processor (12), and the processor (12) is in communication connection with the acquisition module (13), the human-computer interaction module (14), the control signal generation module (15) and the cooling device (2);
the first power factor corrector (16), the first charging module (17) and the first energy storage element (18) are electrically connected in sequence, the positive electrode of the first energy storage element (18) is electrically connected with the positive electrode of the first electronic switch (101) of the first electronic switch group (100) and the negative electrode of the second electronic switch (102), the negative electrode of the first electronic switch (101) of the first electronic switch group (100) and the positive electrode of the second electronic switch (102) are electrically connected with the first end of the magnetic stimulation coil (19), and the control electrode of the first electronic switch (101) and the control electrode of the second electronic switch (102) of the first electronic switch group (10) are both in communication connection with the control signal generation module (15);
the second power factor corrector (160), the second charging module (170) and the second energy storage element (180) are electrically connected in sequence, and the positive pole of the second energy storage element (180) is electrically connected with the second end of the magnetic stimulation coil (19), the first end of the magnetic stimulation coil (19) is electrically connected with the positive electrode of the third electronic switch (201) and the negative electrode of the fourth electronic switch (202) of the second electronic switch group (200), the negative electrode of a third electronic switch (201) and the positive electrode of a fourth electronic switch (202) of the second electronic switch group (200) are electrically connected with the second energy storage element (180), the control electrode of a third electronic switch (201) and the control electrode of a fourth electronic switch (202) of the second electronic switch group (200) are both connected with the control signal generation module (15) in a communication way, the second end of the magnetic stimulation coil (19) is connected with the negative pole of the first energy storage element (18).
2. The transcranial magnetic stimulation system according to claim 1, wherein the acquisition module (13) comprises an acquisition unit (130), a preamplifier (131), a notch filter (132), a programmed amplifier (133), a band-pass filter (134), an a/D converter (135), a first single-chip microcomputer (136), a digital signal processor (137), a first isolation transceiver, and a first surge protector; the acquisition unit (130), the preamplifier (131), the notch filter (132), the program-controlled amplifier (133), the band-pass filter (134), the A/D converter (135), the first single chip microcomputer (136) and the digital signal processor (137) are electrically connected in sequence, the first single chip microcomputer (136) is electrically connected with the program-controlled amplifier (133), the first isolation transceiver is electrically connected with the first surge protector, and the first surge protector is electrically connected between the program-controlled amplifier (133) and the first single chip microcomputer (136).
3. The transcranial magnetic stimulation system according to claim 1, wherein the cooling device (2) comprises a second isolation transceiver, a second surge protector, a second single chip microcomputer (20), an isolator (21), a water pump (22), an air pump (23), a water tank (24), a flow sensor (25), and a temperature sensor (26); transceiver, second surge protector, second singlechip (20), isolator (21) electric connection in proper order are kept apart to the second, water pump (22) and air pump (23) all with isolator (21) electric connection, just water pump (22) and air pump (23) all with water tank (24) are connected, water tank (24) of cooling device (2) with magnetism stimulating coil (19) are connected, flow sensor (25) and temperature sensor (26) all with second singlechip (20) electric connection, the coolant liquid has been held in water tank (24).
4. The transcranial magnetic stimulation system according to claim 3, wherein the cooling device (2) further comprises a fan (27), the fan (27) being disposed adjacent to the water pump (22) and being electrically connected to the isolator (21).
5. The transcranial magnetic stimulation system according to claim 3, wherein the cooling device (2) further comprises a hydraulic sensor (28) and a fluid level sensor (29); hydraulic pressure sensor (28) with second singlechip (20) electric connection, level sensor (29) with second singlechip (20) electric connection and being located in water tank (24), hydraulic pressure sensor (28) are used for detecting cooling liquid pressure and upload to the hydraulic information that detects second singlechip (20), level sensor (28) are used for detecting the liquid level in the water tank and upload to the liquid level information that detects second singlechip (20), second singlechip (20) pass through liquid level information and hydraulic information treater (12) upload to computer (11), the touch screen of computer (11) shows liquid level information and hydraulic information.
6. The transcranial magnetic stimulation system according to claim 1, wherein the human-computer interaction module (14) comprises a key matrix (141), a third single-chip microcomputer (142), a sound generator (143), a third isolation transceiver and a third surge protector, the key matrix (141), the sound generator (143), the third isolation transceiver and the third surge protector are electrically connected with the third single-chip microcomputer (142), and the third single-chip microcomputer (142) is in communication connection with the processor (12).
7. The transcranial magnetic stimulation system according to claim 6, wherein the human-computer interaction module (14) further comprises a breathing lamp (144) and a programmable driver (145), and the programmable driver (145) is electrically connected between the third single-chip microcomputer (142) and the breathing lamp (144).
8. The transcranial magnetic stimulation system according to claim 1, wherein the control signal generation module (15) comprises a delay unit 150, a fourth isolation transceiver, a fourth surge protector, a fourth single chip microcomputer (151), and a photoelectric isolation chip (152), and the delay unit (150), the fourth isolation transceiver, the fourth surge protector, and the photoelectric isolation chip (152) are electrically connected to the fourth single chip microcomputer (151).
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