Background
The skin is the largest organ of the human body and is the natural barrier protecting the body. For severe skin defect patients, a great amount of body fluid loss and wound infection are main factors threatening the life of the patients, and the wound dressing is used as a temporary covering of the wound, can provide a relatively stable healing environment for the wound surface and plays an important role in the process of wound healing. The traditional absorbent cotton gauze has the remarkable advantages of wide raw material source, simple preparation, low cost and the like, and is widely applied to clinical treatment of various wounds.
However, the following drawbacks of conventional gauze limit its application to complex wounds, especially chronic wounds: firstly, the adhesive dressing has an adhesion effect on wounds (particularly infected wounds), so that secondary wounds are easy to be caused to the wounds in the daily replacement process, and pains are brought to patients; secondly, from the molecular structure of gauze, it has no antibacterial effect. Therefore, it is very necessary to develop a new gauze that does not adhere to the wound, and at the same time has the functions of sterilization, anti-infection and promoting the wound healing.
Disclosure of Invention
The invention aims to provide oil gauze and a preparation method thereof.
The above object of the present invention is achieved by the following technical solutions:
the oil gauze is characterized by comprising the following components in parts by volume: 25-35% of white beeswax, 50-55% of peanut oil, 1-3% of honey and 10-19% of a four-yellow decoction, wherein the four-yellow decoction comprises 6% of golden cypress, 5% of coptis chinensis, 4% of rheum officinale and 4% of scutellaria baicalensis.
Further, according to parts by volume: 25% of white beeswax, 55% of peanut oil, 1% of honey and 19% of a Sihuang decoction, wherein the Sihuang decoction comprises 6% of golden cypress, 5% of coptis chinensis, 4% of rheum officinale and 4% of scutellaria baicalensis.
Further, the preparation method comprises the following steps:
a. preparing decoction of four ingredients: grinding cortex Phellodendri, Coptidis rhizoma, radix et rhizoma Rhei, and Scutellariae radix, sieving, adding 5 times of clear water, and decocting for 30-60min to obtain decoction of radix et rhizoma Rhei;
b. preparing an ointment: boiling Cera flava, oleum Arachidis Hypogaeae and Mel in container, adding the decoction of radix Scutellariae, stirring, and cooling to obtain unguent;
c. preparing oil gauze: sterilizing gauze in high temperature and high pressure environment for 15 min, soaking the sterilized gauze and the ointment in a sterile soaking tank for 8-24 hr, and drying in sterile environment to obtain the oily gauze.
In conclusion, the beneficial technical effects of the invention are as follows:
(1) the four-yellow, white beeswax, honey and peanut oil are used as raw materials for preparing the oil gauze, and the prepared oil gauze has the advantages of adhesion prevention, antibiosis and wound healing promotion;
(2) the preparation method is simple, the gauze is used, the preparation cost is low, and the economic pressure of patients is reduced.
Detailed Description
In order to clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following will briefly describe the embodiments or the technical solutions in the prior art, and it is obvious that the following descriptions are only some embodiments of the present invention, and it is obvious for a person skilled in the art to obtain other embodiments according to the embodiments without creative efforts.
The invention is further illustrated below:
an oil gauze comprises the following components in parts by volume: 25% of white beeswax, 55% of peanut oil, 1% of honey and 19% of a Sihuang decoction, wherein the Sihuang decoction comprises 6% of golden cypress, 5% of coptis chinensis, 4% of rheum officinale and 4% of scutellaria baicalensis.
The preparation method comprises the following steps:
a. preparing decoction of four ingredients: grinding and sieving cortex Phellodendri, Coptidis rhizoma, radix et rhizoma Rhei, and Scutellariae radix, adding 5 times of clear water, and decocting for 40min to obtain decoction of radix et rhizoma Rhei;
b. preparing an ointment: boiling Cera flava, oleum Arachidis Hypogaeae and Mel in container, adding the decoction of radix Scutellariae, stirring, and cooling to obtain unguent;
c. preparing oil gauze: sterilizing gauze in high temperature and high pressure environment for 15 min, soaking the sterilized gauze and the ointment in a sterile soaking tank for 12 hr, and drying in sterile environment to obtain the oily gauze.
Clinical use: when dressing change is carried out, the wound surface and surrounding tissues are cleaned firstly, alcohol or other disinfectant is used for repeated disinfection, foreign matters, secretions and necrotic tissues in the wound are cleared, a certain amount of proper oil gauze is placed and covered on granulation tissues of the wound surface, and dressing change is carried out once a day until the wound surface is healed.
The clinical curative effect is as follows: in 95 patients, the ointment reduces the wound adhesion by 96 percent, and compared with the common gauze, the healing time is averagely reduced by 3.7 days.
Selecting patients of different ages
Sorgo, woman, age 88, chief complaints: skin ulcer of the lateral malleolus of the left foot for 2 weeks; physical examination: superficial ulcer of about 3cm diameter of lateral malleolus of left foot, clear border, and small amount of purulent secretion on surface; and (3) diagnosis: foot skin infections; treatment: washing the ulcer surface with normal saline, wiping the dry cotton swab from inside to outside, and covering with four-yellow bee honey oil gauze, and changing the dressing for 1 time each day; as a result: the ulcer heals after 10 days, and light brown pigmentation is left without scar formation.
Roche, male, age 76, chief complaint: repeated double calf skin erosion for 2 years; physical examination: dark brown pigmentation of double crus, 8 erosion faces with the diameter of about 3mm to 5mm scattered at the far end of the double crus, and liquid seepage; and (3) diagnosis: stasis dermatitis; treatment: washing the erosion face with normal saline, wiping with dry cotton swab, and covering with four-yellow bee honey oil gauze, and changing the medicine for 1 time each day; as a result: after 12 days the ulcer healed completely, leaving brown pigmentation with no scar formation.
Wu, male, 59 years old, chief complaints: perineal rash with pain for half a month; physical examination: skin ulcer of about 4cm × 2.5cm on the abdominal side of scrotum, clear boundary, no creeping, flush basal plane, and large amount of yellowish white purulent secretion on the surface; and (3) diagnosis: perineal skin infections; treatment: washing the ulcer surface of scrotum with normal saline, wiping the dry cotton swab from inside to outside, and covering with four-yellow bee honey oil gauze, and changing the dressing for 1 time each day; and (4) conclusion: after 14 days, the ulcer is completely healed, the skin color is light red, and no scar is formed.
Pangam, male, age 26, chief complaints: flushing and erosion of perineum and buttocks for 4 days; physical examination: diaper areas of perineum and buttocks show large flush, superficial erosion and pale yellow serous fluid; and (3) diagnosis: diaper dermatitis; treatment: washing perineum and buttocks with normal saline, wiping the sterile yarn from inside to outside, covering with four-yellow bee honey oil yarn, and changing the medicine for 1 time each day; as a result: the erosion face is completely healed after 3 days, the skin color is normal, and no scar is formed.
The above description is only an embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that are not thought of through the inventive work should be included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope defined by the claims.