CN111840755A - A guide wire for interventional therapy - Google Patents

Abstract

The invention discloses a guide wire for interventional therapy, which comprises: first core silk, second core silk and pillar, first core silk one end and second core silk one end are connected, and the pillar is established outside the second core silk, is provided with a plurality of kerfs that are the arc setting on the pillar, and the kerfs of the crisscross cutting that this pillar set up have good power transmissibility, resistance to deformation ability and firmness, make the doctor in the control of first core silk can in time transmit the second core silk, have strengthened the control of seal wire and have passed through the pathological change ability.

Description

Translated fromChinese

一种介入治疗用导丝A guide wire for interventional therapy

技术领域technical field

本发明涉及介入治疗技术领域，特别涉及一种介入治疗用导丝。The invention relates to the technical field of interventional therapy, in particular to a guide wire for interventional therapy.

背景技术Background technique

介入治疗术具有创伤小、病人术后恢复快、住院时间短等优点，近年来越来越多受到医生和病人的肯定，也得到了较为快速的发展。介入导丝作为引导和定位器械，已广泛应用与介入治疗手术中，在手术过程中，导丝位于最前方探索行进通道，对后续治疗器械能否顺利输送，手术能否成功起到决定性作用。Interventional therapy has the advantages of less trauma, quick postoperative recovery, and short hospital stay. As a guiding and positioning device, the interventional guide wire has been widely used in interventional surgery. During the operation, the guide wire is positioned at the forefront to explore the travel channel, which plays a decisive role in the smooth delivery of subsequent treatment devices and the success of the operation.

现有导丝远端芯丝采用多锥度磨细加工，在磨细段外层缠绕的金属丝，该结构不利于导丝远端的力传递，使得导丝操控性较差，医生在导丝近端操作导丝时，导丝远端没有相应的扭控跟随和响应，从而使导丝很难通过复杂结构的腔道或病变，同时由于远端芯丝磨细加工后在手术中很容易发生变形，变形后导丝操控性进一步变差，甚至导致缠绕的金属丝发生脱丝现象，给病人带来风险。The core wire at the distal end of the existing guide wire is processed by multi-taper grinding, and the metal wire is wound on the outer layer of the grinding section. When the guide wire is operated at the proximal end, the distal end of the guide wire does not have corresponding torsion to follow and respond, which makes it difficult for the guide wire to pass through the lumen or lesions of complex structures. Deformation occurs, and the controllability of the guide wire is further deteriorated after the deformation, and even leads to the de-wire phenomenon of the entangled metal wire, which brings risks to the patient.

发明内容SUMMARY OF THE INVENTION

本发明的目的在于至少解决现有技术中存在的技术问题之一，提供一种介入治疗用导丝，能够增强导丝的可操控性和通过病变能力。The purpose of the present invention is to solve at least one of the technical problems existing in the prior art, and to provide a guide wire for interventional therapy, which can enhance the maneuverability of the guide wire and the ability to pass through lesions.

根据本发明的第一方面实施例，提供一种介入治疗用导丝，包括：第一芯丝、第二芯丝以及护管，所述第一芯丝一端和所述第二芯丝一端连接，所述护管套设在所述第二芯丝外，所述护管上设置有若干呈弧形设置的切缝。According to an embodiment of the first aspect of the present invention, a guide wire for interventional therapy is provided, comprising: a first core wire, a second core wire and a protective tube, one end of the first core wire is connected to one end of the second core wire , the protective tube is sleeved outside the second core wire, and the protective tube is provided with a plurality of slits arranged in an arc shape.

有益效果：此介入治疗用导丝，包括：第一芯丝、第二芯丝以及护管，第一芯丝一端和第二芯丝一端连接，护管套设在第二芯丝外，护管上设置有若干呈弧形设置的切缝，此护管设置的交错切割的切缝，具有良好的力传递性、抗变形能力和牢固度，使医生在第一芯丝的操控能及时地传递到第二芯丝，增强了导丝的操控性和通过病变能力。Beneficial effects: the guide wire for interventional therapy includes: a first core wire, a second core wire and a protective tube, one end of the first core wire is connected with one end of the second core wire, the protective tube is sleeved outside the second core wire, and the protective tube is The tube is provided with a number of slits arranged in an arc shape. The staggered slits set on the protective tube have good force transmission, deformation resistance and firmness, so that the doctor can control the first core wire in a timely manner. Pass to the second core wire, enhancing the maneuverability of the guide wire and the ability to pass the lesion.

根据本发明第一方面实施例所述的介入治疗用导丝，各所述切缝与所述第二芯丝的轴向方向垂直或者呈夹角设置，且所述切缝的圆心位于所述第二芯丝的轴线上。According to the guide wire for interventional therapy according to the embodiment of the first aspect of the present invention, each of the slits is perpendicular to or at an angle to the axial direction of the second core wire, and the center of the slit is located in the on the axis of the second core wire.

根据本发明第一方面实施例所述的介入治疗用导丝，相邻所述切缝相背设置。According to the guide wire for interventional therapy according to the embodiment of the first aspect of the present invention, the adjacent incisions are arranged opposite to each other.

根据本发明第一方面实施例所述的介入治疗用导丝，所述第二芯丝远离第一芯丝的一端为头端，各所述切缝的弧长随着所述切缝与所述头端的距离的增加而减小。According to the guide wire for interventional therapy according to the embodiment of the first aspect of the present invention, the end of the second core wire away from the first core wire is the head end, and the arc length of each slit follows the distance between the slit and the It decreases as the distance from the head end increases.

根据本发明第一方面实施例所述的介入治疗用导丝，当所述切缝为两条以上时，相邻所述切缝之间的节距随着所述切缝与所述头端的距离增加而增加。According to the guide wire for interventional therapy according to the embodiment of the first aspect of the present invention, when there are more than two incisions, the pitch between the adjacent incisions follows the distance between the incisions and the head end. increases with distance.

根据本发明第一方面实施例所述的介入治疗用导丝，所述第二芯丝和所述护管之间设置有显影层，所述显影层设置在所述第二芯丝外，以使导丝在X射线下具有可视性。According to the guide wire for interventional therapy according to the embodiment of the first aspect of the present invention, a developing layer is provided between the second core wire and the protective tube, and the developing layer is provided outside the second core wire to Make the guidewire visible under X-ray.

根据本发明第一方面实施例所述的介入治疗用导丝，所述第二芯丝和所述护管的外表面均涂覆有亲水涂层，减小导丝与人体腔道之间的相互摩擦力。According to the guide wire for interventional therapy according to the embodiment of the first aspect of the present invention, the outer surfaces of the second core wire and the protective tube are coated with a hydrophilic coating to reduce the gap between the guide wire and the human body cavity. of mutual friction.

根据本发明第一方面实施例所述的介入治疗用导丝，所述护管的为镍钛合金薄壁管，所述护管通过激光切割加工形成切缝，具有良好的弹性和抗变形能力，而且提供优异的扭控性。According to the guide wire for interventional therapy according to the embodiment of the first aspect of the present invention, the protective tube is a nickel-titanium alloy thin-walled tube, and the protective tube is laser-cut to form a slit, which has good elasticity and deformation resistance. , and provides excellent torque control.

根据本发明第一方面实施例所述的介入治疗用导丝，所述第一芯丝的材质为不锈钢，所述第一芯丝的外表面涂覆有疏水涂层，有效降低与器械之间的摩擦力。According to the guide wire for interventional therapy according to the embodiment of the first aspect of the present invention, the material of the first core wire is stainless steel, and the outer surface of the first core wire is coated with a hydrophobic coating, which effectively reduces the distance between the first core wire and the instrument. friction force.

根据本发明第一方面实施例所述的介入治疗用导丝，所述第二芯丝材质为镍钛合金，所述第二芯丝呈多锥度设置，确保导丝的头端柔顺性。According to the guide wire for interventional therapy according to the embodiment of the first aspect of the present invention, the second core wire is made of nickel-titanium alloy, and the second core wire is provided with multiple tapers to ensure the flexibility of the tip end of the guide wire.

附图说明Description of drawings

下面结合附图和实施例对本发明进一步地说明；Below in conjunction with accompanying drawing and embodiment, the present invention is further described;

图1为本发明实施例护管实施例1示意图；FIG. 1 is a schematic diagram of Embodiment 1 of a protective tube according to an embodiment of the present invention;

图2为本发明实施例护管实施例2示意图；FIG. 2 is a schematic diagram of Embodiment 2 of a protective tube according to an embodiment of the present invention;

图3为本发明实施例护管实施例3示意图；3 is a schematic diagram of Embodiment 3 of a protective tube according to an embodiment of the present invention;

图4为图3中A-A剖视图；Fig. 4 is A-A sectional view in Fig. 3;

图5为图3中B-B剖视图；Fig. 5 is B-B sectional view in Fig. 3;

图6为图3中C-C剖视图；Fig. 6 is C-C sectional view in Fig. 3;

图7为图3中D-D剖视图；Fig. 7 is D-D sectional view in Fig. 3;

图8为本发明实施例护管实施例切缝节距示意图；FIG. 8 is a schematic diagram of the slit pitch of an embodiment of a protective tube according to an embodiment of the present invention;

图9为本发明实施例第一芯丝和第二芯丝示意图；9 is a schematic diagram of a first core wire and a second core wire according to an embodiment of the present invention;

图10为本发明实施例介入治疗用导丝实施例1剖视图；10 is a cross-sectional view of Embodiment 1 of a guide wire for interventional therapy according to an embodiment of the present invention;

图11为本发明实施例介入治疗用导丝实施例2剖视图；11 is a cross-sectional view of Embodiment 2 of a guide wire for interventional therapy according to an embodiment of the present invention;

图12为本发明实施例介入治疗用导丝实施例3剖视图。12 is a cross-sectional view of the third embodiment of the guide wire for interventional therapy according to the embodiment of the present invention.

具体实施方式Detailed ways

本部分将详细描述本发明的具体实施例，本发明之较佳实施例在附图中示出，附图的作用在于用图形补充说明书文字部分的描述，使人能够直观地、形象地理解本发明的每个技术特征和整体技术方案，但其不能理解为对本发明保护范围的限制。This part will describe the specific embodiments of the present invention in detail, and the preferred embodiments of the present invention are shown in the accompanying drawings. Each technical feature and overall technical solution of the invention should not be construed as limiting the protection scope of the invention.

在本发明的描述中，需要理解的是，涉及到方位描述，例如上、下、前、后、左、右等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。In the description of the present invention, it should be understood that the azimuth description, such as the azimuth or position relationship indicated by up, down, front, rear, left, right, etc., is based on the azimuth or position relationship shown in the drawings, only In order to facilitate the description of the present invention and simplify the description, it is not indicated or implied that the indicated device or element must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.

在本发明的描述中，若干的含义是一个或者多个，多个的含义是两个以上，大于、小于、超过等理解为不包括本数，以上、以下、以内等理解为包括本数。如果有描述到第一、第二只是用于区分技术特征为目的，而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量或者隐含指明所指示的技术特征的先后关系。In the description of the present invention, the meaning of several is one or more, the meaning of multiple is two or more, greater than, less than, exceeding, etc. are understood as not including this number, above, below, within, etc. are understood as including this number. If it is described that the first and the second are only for the purpose of distinguishing technical features, it cannot be understood as indicating or implying relative importance, or indicating the number of the indicated technical features or the order of the indicated technical features. relation.

本发明的描述中，除非另有明确的限定，设置、安装、连接等词语应做广义理解，所属技术领域技术人员可以结合技术方案的具体内容合理确定上述词语在本发明中的具体含义。In the description of the present invention, unless otherwise clearly defined, words such as setting, installation, connection should be understood in a broad sense, and those skilled in the art can reasonably determine the specific meanings of the above words in the present invention in combination with the specific content of the technical solution.

参照图10至图12，一种介入治疗用导丝，包括：第一芯丝100、第二芯丝200以及护管300，第一芯丝100一端和第二芯丝200一端连接，护管300套设在第二芯丝200外，护管300上设置有若干呈弧形设置的切缝310。10 to 12, a guide wire for interventional therapy includes: afirst core wire 100, asecond core wire 200 and aprotective tube 300, one end of thefirst core wire 100 is connected to one end of thesecond core wire 200, and the protective tube Theprotective tube 300 is provided with a plurality ofslits 310 arranged in an arc shape.

其中，在图上所示左右方向为导丝轴向方向。左端为导丝远端方向，右端为导丝近端方向。Among them, the left-right direction shown in the figure is the axial direction of the guide wire. The left end is the direction of the distal end of the guide wire, and the right end is the direction of the proximal end of the guide wire.

参照图9，其中，第一芯丝100为近端芯丝，第二芯丝200为远端芯丝。第一芯丝100提供导丝整体的扭控性和推送性，第二芯丝200经磨细加工后具有良好的柔顺性。护管300为管材交错切割结构，具有良好的力传递性、抗变形能力和牢固度，使医生在第一芯丝100的操控能及时传递到第二芯丝200，增强了导丝的操控性和通过病变能力。Referring to FIG. 9 , thefirst core wire 100 is a proximal core wire, and thesecond core wire 200 is a distal core wire. Thefirst core wire 100 provides the overall twist control and pushability of the guide wire, and thesecond core wire 200 has good flexibility after being ground and processed. Theprotective tube 300 is a tube material staggered cutting structure, which has good force transmission, deformation resistance and firmness, so that the doctor's manipulation of thefirst core wire 100 can be transferred to thesecond core wire 200 in time, and the manipulation of the guide wire is enhanced. and the ability to pass lesions.

参照图1至图3，具体地，各切缝310与第二芯丝200的轴向方向垂直或者呈夹角设置，且切缝310的圆心位于第二芯丝200的轴线上。进一步地，为了优化护管300的力传递性和柔顺性。切缝310均不是完整环形，例如切割3/4圈，保留1/4圈不切割，相邻两个切缝310间保留不切的部分位置相背设置，即相邻切缝310相背设置，这样能兼顾柔顺性与力传导性。Referring to FIGS. 1 to 3 , specifically, eachslit 310 is perpendicular to or at an angle to the axial direction of thesecond core wire 200 , and the center of theslit 310 is located on the axis of thesecond core wire 200 . Further, in order to optimize the force transmission and compliance of theprotective tube 300 . None of theslits 310 is a complete ring, for example, 3/4 circle is cut, 1/4 circle is not cut, and the uncut parts between twoadjacent slits 310 are arranged opposite to each other, that is,adjacent slits 310 are arranged opposite to each other. , which can take into account both flexibility and force conductivity.

参照图4至图7，为了使护管300不同位置适应病变不同的支撑性和柔顺性要求，每一个切缝310保留不切部分的弧长是变化的，第二芯丝200远离第一芯丝100的一端为头端，头端处的护管300的不切部分弧长较小，确保头端具有良好的柔软性，不损伤血管，不切部分弧长随着距离头端距离增加而不断加大，即各切缝310的弧长随着切缝310与头端的距离的增加而减小，确保导丝远端护管300的柔顺性逐渐过渡。Referring to FIGS. 4 to 7 , in order to adapt the different positions of theprotective tube 300 to different support and flexibility requirements of the lesion, the arc length of the uncut portion of eachslit 310 is changed, and thesecond core wire 200 is far away from the first core One end of thewire 100 is the head end, and the arc length of the uncut part of theprotective tube 300 at the head end is relatively small to ensure that the head end has good flexibility and does not damage the blood vessels. The arc length of the uncut part increases with the distance from the head end. Continuously increasing, that is, the arc length of eachslit 310 decreases as the distance between theslit 310 and the head end increases, so as to ensure that the flexibility of the distal end of theguide wire 300 is gradually transitioned.

参照图8，为了使护管300不同位置适应病变不同的支撑性和柔顺性要求，当切缝310为两条以上时，相邻切缝310之间的节距P是变化的，导丝远端头端处节距Pn较小，确保头端具有良好的柔软性，不损伤血管，相邻切缝310之间的节距随着切缝310与头端的距离增加而增加，距离头端最远处节距P1较大，确保导丝远端护管300的柔顺性逐渐过渡。Referring to FIG. 8 , in order to adapt the different positions of theprotective tube 300 to the different support and flexibility requirements of the lesions, when there are more than twoincisions 310, the pitch P between theadjacent incisions 310 is changed, and the guide wire is farther away. The pitch Pn at the tip end is small to ensure that the tip end has good flexibility and does not damage the blood vessels. The distal pitch P1 is relatively large, which ensures a gradual transition of the flexibility of the guide wire distalprotective tube 300 .

参照图10至图12，在一个实施例中，一种介入治疗用导丝，包括：第一芯丝100、第二芯丝200以及护管300，第一芯丝100一端和第二芯丝200一端连接，护管300套设在第二芯丝200外，护管300上设置有若干呈弧形设置的切缝310，第二芯丝200和护管300之间设置有显影层400，显影层400焊接在第二芯丝200外。设置显影层400提高了导丝在X射线下的可视性。10 to 12 , in one embodiment, a guide wire for interventional therapy includes: afirst core wire 100 , asecond core wire 200 and aprotective tube 300 , one end of thefirst core wire 100 and the second core wire One end of the 200 is connected, theprotective tube 300 is sleeved on the outside of thesecond core wire 200, theprotective tube 300 is provided with a plurality ofslits 310 arranged in an arc shape, and a developinglayer 400 is arranged between thesecond core wire 200 and theprotective tube 300, The developinglayer 400 is welded outside thesecond core wire 200 . The provision of theimaging layer 400 improves the visibility of the guide wire under X-rays.

可以理解地，第二芯丝200和护管300的外表面均涂覆有亲水涂层500，亲水涂层500降低导丝与人体腔道之间的摩擦力，提高导丝润滑度和通过能力。It can be understood that the outer surfaces of thesecond core wire 200 and theprotective tube 300 are coated with ahydrophilic coating 500. Thehydrophilic coating 500 reduces the friction between the guide wire and the human body cavity, and improves the lubricity of the guide wire. through ability.

在一个实施例中，一种介入治疗用导丝，包括：第一芯丝100、第二芯丝200以及护管300，第一芯丝100一端和第二芯丝200一端连接，护管300套设在第二芯丝200外，护管300上设置有若干呈弧形设置的切缝310，护管300的为镍钛合金薄壁管，利用冷光源激光切割进行加工，具有良好的弹性和抗变形能力，而且提供优异的扭控性。第一芯丝100的材质为不锈钢，确保导丝近端的刚性和推送性，第一芯丝100的外表面涂覆有PTFE疏水涂层600，降低与器械间摩擦力。第二芯丝200材质为镍钛合金，提高第二芯丝200的扭控性、柔顺性和抗变形能力，第二芯丝200呈多锥度设置，确保导丝头端柔顺性。In one embodiment, a guide wire for interventional therapy includes: afirst core wire 100, asecond core wire 200 and aprotective tube 300, one end of thefirst core wire 100 is connected to one end of thesecond core wire 200, and theprotective tube 300 It is sleeved outside thesecond core wire 200, and theprotective tube 300 is provided with a number of arc-shapedslits 310. Theprotective tube 300 is a nickel-titanium alloy thin-walled tube, which is processed by laser cutting with a cold light source and has good elasticity. and resistance to deformation, but also provides excellent twist control. The material of thefirst core wire 100 is stainless steel, which ensures the rigidity and pushability of the proximal end of the guide wire. The outer surface of thefirst core wire 100 is coated with a PTFEhydrophobic coating 600 to reduce the friction force with the instrument. Thesecond core wire 200 is made of nickel-titanium alloy, which improves the twist control, flexibility and deformation resistance of thesecond core wire 200. Thesecond core wire 200 is provided with multiple tapers to ensure the flexibility of the guide wire tip.

参照图10，在实施例1中，一种介入治疗用导丝，包括：第一芯丝100、第二芯丝200、护管300、显影层400、疏水涂层600、亲水涂层500以及焊点700。本实施例中，第一芯丝100和第二芯丝200通过焊接方法进行连接，第二芯丝200经磨细加工后具有良好的柔顺性，显影层400利用钎焊工艺焊接在第二芯丝200外，提供X射线下显影性，护管300利用钎焊工艺焊接在第二芯丝200和显影层400外，焊料为Sn-Ag系锡焊，护管300为交错切割结构，切缝310方向垂直于第二芯丝200轴向，切缝310弧长为4/5圈，保留1/5圈不切割，相邻两个切缝310间不切的部分位置相背，相隔切缝310间保留不切部分位置螺旋递进，这样能兼顾柔顺性与力传导性，交错切割采用冷光源激光切割，切割后酸洗去渣，并进行电化学抛光处理，确保护管400表面光滑不损伤血管。第一芯丝100涂覆有PTFE疏水涂层，降低导丝与器械的摩擦力，第二芯丝200涂覆亲水涂层，降低导丝与人体腔道之间的摩擦力，提高导丝通过性。10 , in Embodiment 1, a guide wire for interventional therapy includes: afirst core wire 100 , asecond core wire 200 , aprotective tube 300 , a developinglayer 400 , ahydrophobic coating 600 , and ahydrophilic coating 500 andsolder joint 700. In this embodiment, thefirst core wire 100 and thesecond core wire 200 are connected by a welding method, thesecond core wire 200 has good flexibility after being ground and processed, and the developinglayer 400 is welded on the second core wire by a brazing process. Outside thewire 200, the X-ray developability is provided. Theprotective tube 300 is welded outside thesecond core wire 200 and the developinglayer 400 by a brazing process. The solder is Sn-Ag based soldering. The direction of 310 is perpendicular to the axial direction of thesecond core wire 200, the arc length of theslit 310 is 4/5 circle, and 1/5 circle is not cut. The uncut part of the 310 room is spirally advanced, which can take into account flexibility and force conductivity. The staggered cutting adopts cold light source laser cutting. After cutting, pickling is used to remove slag, and electrochemical polishing is performed to ensure that the surface of theprotective tube 400 is smooth and not. damage blood vessels. Thefirst core wire 100 is coated with a PTFE hydrophobic coating to reduce the friction between the guide wire and the instrument, and thesecond core wire 200 is coated with a hydrophilic coating to reduce the friction between the guide wire and the human body cavity, and improve the guide wire Passability.

参照图11，在实施例2中，一种介入治疗用导丝，包括：第一芯丝100、第二芯丝200、护管300、显影层400、疏水涂层600、亲水涂层500以及焊点700。本实施例中，第一芯丝100和第二芯丝200通过焊接方法进行连接，第二芯丝200经磨细加工后具有良好的柔顺性，显影层400利用钎焊工艺焊接在第二芯丝200外，提供X射线下显影性，护管300利用钎焊工艺焊接在第二芯丝200和显影层400外，焊料为Sn-Ag系锡焊，护管300为交错切割结构，切缝310方向与第二芯丝200轴向垂直，切缝310弧长为4/5圈，保留1/5圈不切割，相邻两个切缝310间不切的部分位置相背，相邻切缝310件保留不切部分位置螺旋递进，这样能兼顾柔顺性与力传导性，同时相邻切缝310之间节距P是变化的，第二芯丝200头端处节距Pn较小，确保头端具有良好的柔软性，不损伤血管，节距随着距离头端距离增加而不断增加，距离头端最远处节距P1较大，确保导丝远端护管300的柔顺性逐渐过渡。交错切割采用冷光源激光切割，切割后酸洗去渣，并进行电化学抛光处理，确保护管400表面光滑不损伤血管。第一芯丝100涂覆有PTFE疏水涂层，降低导丝与器械的摩擦力，第二芯丝200涂覆亲水涂层，降低导丝与人体腔道之间的摩擦力，提高导丝通过性。11 , in Embodiment 2, a guide wire for interventional therapy includes: afirst core wire 100 , asecond core wire 200 , aprotective tube 300 , a developinglayer 400 , ahydrophobic coating 600 , and ahydrophilic coating 500 andsolder joint 700. In this embodiment, thefirst core wire 100 and thesecond core wire 200 are connected by a welding method, thesecond core wire 200 has good flexibility after being ground and processed, and the developinglayer 400 is welded on the second core wire by a brazing process. Outside thewire 200, the X-ray developability is provided. Theprotective tube 300 is welded outside thesecond core wire 200 and the developinglayer 400 by a brazing process. The solder is Sn-Ag based soldering. The direction of 310 is perpendicular to the axial direction of thesecond core wire 200, the arc length of theslit 310 is 4/5 of a circle, and 1/5 of a circle is not cut. Theslits 310 are kept at the uncut portion and the position is spirally advanced, so that both flexibility and force conductivity can be taken into account. At the same time, the pitch P between theadjacent slits 310 is changed, and the pitch Pn at the head end of thesecond core wire 200 is smaller. , to ensure that the tip has good flexibility and does not damage blood vessels, the pitch increases with the distance from the tip, and the pitch P1 at the farthest distance from the tip is larger to ensure the flexibility of the guide wiredistal protection tube 300 Gradually transition. The staggered cutting adopts cold light source laser cutting, pickling to remove slag after cutting, and electrochemical polishing treatment is performed to ensure that the surface of theprotective tube 400 is smooth and does not damage the blood vessels. Thefirst core wire 100 is coated with a PTFE hydrophobic coating to reduce the friction between the guide wire and the instrument, and thesecond core wire 200 is coated with a hydrophilic coating to reduce the friction between the guide wire and the human body cavity, and improve the guide wire Passability.

参照图12，在实施例3中，一种介入治疗用导丝，包括：第一芯丝100、第二芯丝200、护管300、显影层400、疏水涂层600、亲水涂层500以及焊点700。本实施例中，第一芯丝100和第二芯丝200通过焊接方法进行连接，第二芯丝200经磨细加工后具有良好的柔顺性，显影层400利用钎焊工艺焊接在第二芯丝200外，提供X射线下显影性，护管300利用钎焊工艺焊接在第二芯丝200和显影层400外，焊料为Sn-Ag系锡焊，护管300为交错切割结构，切缝310方向与第二芯丝200轴向成80°角，切缝310弧长为4/5圈，保留1/5圈不切割，相邻两个切缝310间不切的部分位置相背。交错切割采用冷光源激光切割，切割后酸洗去渣，并进行电化学抛光处理，确保护管400表面光滑不损伤血管。第一芯丝100涂覆有PTFE疏水涂层，降低导丝与器械的摩擦力，第二芯丝200涂覆亲水涂层，降低导丝与人体腔道之间的摩擦力，提高导丝通过性。12 , in Embodiment 3, a guide wire for interventional therapy includes: afirst core wire 100 , asecond core wire 200 , aprotective tube 300 , a developinglayer 400 , ahydrophobic coating 600 , and ahydrophilic coating 500 andsolder joint 700. In this embodiment, thefirst core wire 100 and thesecond core wire 200 are connected by a welding method, thesecond core wire 200 has good flexibility after being ground and processed, and the developinglayer 400 is welded on the second core wire by a brazing process. Outside thewire 200, the X-ray developability is provided. Theprotective tube 300 is welded outside thesecond core wire 200 and the developinglayer 400 by a brazing process. The solder is Sn-Ag based soldering. The direction of 310 forms an angle of 80° with the axial direction of thesecond core wire 200 , the arc length of theslit 310 is 4/5 of a circle, and 1/5 of a circle is left uncut, and the uncut parts between twoadjacent slits 310 are in opposite positions. The staggered cutting adopts cold light source laser cutting, pickling to remove slag after cutting, and electrochemical polishing treatment is performed to ensure that the surface of theprotective tube 400 is smooth and does not damage the blood vessels. Thefirst core wire 100 is coated with a PTFE hydrophobic coating to reduce the friction between the guide wire and the instrument, and thesecond core wire 200 is coated with a hydrophilic coating to reduce the friction between the guide wire and the human body cavity, and improve the guide wire Passability.

上面结合附图对本发明实施例作了详细说明，但是本发明不限于上述实施例，在所述技术领域普通技术人员所具备的知识范围内，还可以在不脱离本发明宗旨的前提下作出各种变化。The embodiments of the present invention have been described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above-mentioned embodiments. Within the scope of knowledge possessed by those of ordinary skill in the technical field, various modifications can be made without departing from the purpose of the present invention. kind of change.

Claims (10)

Translated fromChinese

1.一种介入治疗用导丝，其特征在于，包括：1. a guide wire for interventional therapy, characterized in that, comprising:第一芯丝；the first core wire;第二芯丝，所述第一芯丝一端和所述第二芯丝一端连接；以及a second core wire, one end of the first core wire is connected to one end of the second core wire; and护管，所述护管套设在所述第二芯丝外，所述护管上设置有若干呈弧形设置的切缝。The protective tube is sleeved outside the second core wire, and the protective tube is provided with a plurality of arc-shaped slits.2.根据权利要求1所述的介入治疗用导丝，其特征在于：各所述切缝与所述第二芯丝的轴向方向垂直或者呈夹角设置，且所述切缝的圆心位于所述第二芯丝的轴线上。2 . The guide wire for interventional therapy according to claim 1 , wherein each of the slits is arranged perpendicular to the axial direction of the second core wire or at an included angle, and the center of the slit is located at the center of the slit. 3 . on the axis of the second core wire.3.根据权利要求2所述的介入治疗用导丝，其特征在于：相邻所述切缝相背设置。3 . The guide wire for interventional therapy according to claim 2 , wherein the adjacent incisions are arranged opposite to each other. 4 .4.根据权利要求2所述的介入治疗用导丝，其特征在于：所述第二芯丝远离第一芯丝的一端为头端，各所述切缝的弧长随着所述切缝与所述头端的距离的增加而减小。4 . The guide wire for interventional therapy according to claim 2 , wherein the end of the second core wire away from the first core wire is the head end, and the arc length of each slit follows the slit. 5 . It decreases as the distance from the head end increases.5.根据权利要求4所述的介入治疗用导丝，其特征在于：当所述切缝为两条以上时，相邻所述切缝之间的节距随着所述切缝与所述头端的距离增加而增加。5 . The guide wire for interventional therapy according to claim 4 , wherein when there are more than two incisions, the pitch between the adjacent incisions follows the difference between the incisions and the increases as the distance from the tip increases.6.根据权利要求1至5任一项所述的介入治疗用导丝，其特征在于：所述第二芯丝和所述护管之间设置有显影层，所述显影层设置在所述第二芯丝外。6 . The guide wire for interventional therapy according to claim 1 , wherein a developing layer is provided between the second core wire and the protective tube, and the developing layer is provided on the Outside the second core wire.7.根据权利要求6所述的介入治疗用导丝，其特征在于：所述第二芯丝和所述护管的外表面均涂覆有亲水涂层。7 . The guide wire for interventional therapy according to claim 6 , wherein the outer surfaces of the second core wire and the protective tube are coated with a hydrophilic coating. 8 .8.根据权利要求1至5任一项所述的介入治疗用导丝，其特征在于：所述护管的为镍钛合金薄壁管，所述护管通过激光切割加工形成切缝。8 . The guide wire for interventional therapy according to claim 1 , wherein the protective tube is a nickel-titanium alloy thin-walled tube, and the protective tube is laser-cut to form a slit. 9 .9.根据权利要求1至5任一项所述的介入治疗用导丝，其特征在于：所述第一芯丝的材质为不锈钢，所述第一芯丝的外表面涂覆有疏水涂层。9 . The guide wire for interventional therapy according to claim 1 , wherein the material of the first core wire is stainless steel, and the outer surface of the first core wire is coated with a hydrophobic coating. 10 . .10.根据权利要求1至5任一项所述的介入治疗用导丝，其特征在于：所述第二芯丝材质为镍钛合金，所述第二芯丝呈多锥度设置。10 . The guide wire for interventional therapy according to claim 1 , wherein the second core wire is made of nickel-titanium alloy, and the second core wire is provided with multiple tapers. 11 .

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