CN111772775A

Movatterモバイル変換

Info

Publication number: CN111772775A
Application number: CN202010686951.4A
Authority: CN
Inventors: 赵圣刚
Original assignee: Second Hospital Iaxing
Current assignee: Second Hospital Iaxing
Priority date: 2020-07-16
Filing date: 2020-07-16
Publication date: 2020-10-16

Abstract

Translated fromChinese

本发明公开了一种射频与化学一体化消融方法，利用射频与化学一体化消融装置进行消融，包括步骤：放入装置，将射频与化学一体化消融装置的传输导管沿病人的血管放入，并使得传输导管远端设置的射频消融电极和注射头到达体内需要治疗的病灶部位；连接设备，将传输导管的近端接口连接射频消融控制器和化学消融注射器；实施消融，通过射频消融控制器和化学消融注射器对病灶部位进行射频消融和化学消融；结束处理，当射频消融和化学消融均结束后，取下射频消融控制器和化学消融注射器，再将传输导管从病人的血管中取出，完成消融。本发明实现了同时进行射频消融和化学消融，也可以分时进行射频消融和化学消融，有利于消融效果的改进和提升。

The invention discloses a radio frequency and chemical integrated ablation method, which utilizes a radio frequency and chemical integrated ablation device for ablation. And make the radiofrequency ablation electrode and injection head set at the distal end of the transmission catheter reach the lesion that needs to be treated in the body; connect the equipment, and connect the proximal interface of the transmission catheter to the radiofrequency ablation controller and the chemical ablation syringe; implement ablation, through the radiofrequency ablation controller Perform radiofrequency ablation and chemical ablation on the lesion site with the chemical ablation injector; end the treatment, when both radiofrequency ablation and chemical ablation are completed, remove the radiofrequency ablation controller and chemical ablation injector, and then take out the transmission catheter from the patient's blood vessel, complete ablation. The present invention realizes simultaneous radio frequency ablation and chemical ablation, and can also perform radio frequency ablation and chemical ablation in time division, which is beneficial to the improvement and promotion of the ablation effect.

Description

Translated fromChinese

一种射频与化学一体化消融方法A radiofrequency and chemical integrated ablation method

技术领域technical field

本发明涉及医疗领域，尤其涉及一种射频与化学一体化消融方法。The invention relates to the medical field, in particular to a radio frequency and chemical integrated ablation method.

背景技术Background technique

射频消融术是将射频消融导管经血管送入特定部位，通过释放射频电流导致特定部位的局部神经和组织凝固性坏死，以达到阻断传导束或起源点的介入性技术。由于射频电流具有损伤范围小，不造成机体危害的优点，目前已经广泛应用于治疗心律失常、高血压、糖尿病和癌症肿瘤等。Radiofrequency ablation is an interventional technique in which a radiofrequency ablation catheter is delivered to a specific site through a blood vessel, and the radiofrequency current is released to cause coagulation and necrosis of local nerves and tissues in a specific site, so as to block the conduction beam or the point of origin. Because RF current has the advantages of small damage range and no harm to the body, it has been widely used in the treatment of arrhythmia, hypertension, diabetes and cancer tumors.

现有技术条件下，采用单一的射频消融的治疗效果对于一些病情复杂的病灶部分并不理想，往往还需要进一步通过化学消融来治疗。但是当前条件下这两种消融治疗过程，需要分开进行，需要分别通过导管进入人体血管，在到达病灶，显然这种方式不仅给病人带来治疗上的痛苦，也会增强治疗成本和治疗风险。因此，有必要开展射频消融与化学消融一体化结合的研究。Under the existing technical conditions, the therapeutic effect of a single radiofrequency ablation is not ideal for some lesions with complex conditions, and further treatment by chemical ablation is often required. However, under the current conditions, these two ablation treatments need to be carried out separately, and they need to enter the human blood vessels through the catheter respectively, and when they reach the lesion, obviously this method not only brings pain to the patient, but also increases the cost and risk of treatment. Therefore, it is necessary to carry out research on the integration of radiofrequency ablation and chemical ablation.

发明内容SUMMARY OF THE INVENTION

本发明主要解决的技术问题是提供一种射频与化学一体化消融方法，解决现有技术中缺乏一体化消融方法，射频消融和化学消融只能独立分开进行的难题。The main technical problem to be solved by the present invention is to provide an integrated radio frequency and chemical ablation method, which solves the problem of lack of an integrated ablation method in the prior art, and radio frequency ablation and chemical ablation can only be performed independently.

为解决上述技术问题，本发明采用的一个技术方案是提供一种射频与化学一体化消融方法，利用射频与化学一体化消融装置进行消融，包括步骤：放入装置，将所述射频与化学一体化消融装置的传输导管沿病人的血管放入，并使得传输导管远端设置的射频消融电极和注射头到达体内需要治疗的病灶部位；连接设备，将传输导管的近端接口连接射频消融控制器和化学消融注射器；实施消融，通过所述射频消融控制器和化学消融注射器对所述病灶部位进行射频消融和化学消融；结束处理，当所述射频消融和化学消融均结束后，取下射频消融控制器和化学消融注射器，再将所述传输导管从病人的血管中取出，完成消融。In order to solve the above technical problems, a technical solution adopted in the present invention is to provide a radio frequency and chemical integrated ablation method, which utilizes a radio frequency and chemical integrated ablation device for ablation, including the steps of: putting into the device, and integrating the radio frequency and chemical ablation method. The transmission catheter of the chemical ablation device is placed along the blood vessel of the patient, and the radio frequency ablation electrode and the injection head set at the distal end of the transmission catheter reach the lesion that needs to be treated in the body; the device is connected, and the proximal interface of the transmission catheter is connected to the radio frequency ablation controller. and chemical ablation injector; perform ablation, and perform radio frequency ablation and chemical ablation on the lesion site through the radio frequency ablation controller and chemical ablation injector; end the process, when the radio frequency ablation and chemical ablation are all finished, remove the radio frequency ablation The controller and chemical ablation injector are then removed from the patient's blood vessel to complete the ablation.

优选的，在所述放入装置步骤中，所述传输导管内设置有连接所述射频消融控制器和射频消融电极的电连接体；所述传输导管还包括连接所述化学消融注射器和注射头的中空管。Preferably, in the step of placing the device, the transmission catheter is provided with an electrical connector for connecting the radiofrequency ablation controller and the radiofrequency ablation electrode; the transmission catheter further comprises a connection between the chemical ablation injector and the injection head of hollow tubes.

优选的，所述中空管设置在所述传输导管外部，所述传输导管的外层为包覆层，所述电连接体内封在所述包覆层的内部，所述包覆层的表面还与所述中空管的外层表面结合为一体，由此形成传输导管的外表面和中空管的外表面结合为一体的双管道结构体。Preferably, the hollow tube is arranged outside the transmission conduit, the outer layer of the transmission conduit is a cladding layer, the electrical connector is enclosed inside the cladding layer, and the surface of the cladding layer is It is also integrated with the outer surface of the hollow tube, thereby forming a double-pipe structure in which the outer surface of the transmission conduit and the outer surface of the hollow tube are integrated into one.

优选的，所述中空管设置在所述传输导管内部，所述传输导管的外层为包覆层，在所述中空管圆心套装在所述包覆层的内部，在所述包覆层与所述中空管之间设置有隔离层，所述电连接体设置在隔离层，由此形成中空管和电连接体套装在所述传输导管内部的一体化结构体。Preferably, the hollow tube is arranged inside the transmission conduit, the outer layer of the transmission conduit is a cladding layer, the hollow tube is sheathed inside the cladding layer, and the cladding layer is An isolation layer is arranged between the layer and the hollow tube, and the electrical connector is arranged on the isolation layer, thereby forming an integrated structure in which the hollow tube and the electrical connector are sheathed inside the transmission conduit.

优选的，在所述连接设备步骤中，所述传输导管的近端接口可同时连接射频消融控制器和化学消融注射器；在所述实施消融步骤中，射频消融和化学消融可同时进行或射频消融和化学消融分时进行。Preferably, in the step of connecting the equipment, the proximal interface of the transmission catheter can be connected to the radiofrequency ablation controller and the chemical ablation injector at the same time; in the step of performing ablation, the radiofrequency ablation and the chemical ablation can be performed simultaneously or the radiofrequency ablation and chemical ablation time-sharing.

优选的，在所述连接设备步骤中，所述传输导管的近端接口可选择地连接射频消融控制器或化学消融注射器；在所述实施消融步骤中，射频消融和化学消融分时进行。Preferably, in the step of connecting the device, the proximal interface of the transmission catheter is selectively connected to a radiofrequency ablation controller or a chemical ablation injector; in the step of performing ablation, radiofrequency ablation and chemical ablation are performed at different times.

优选的，在所述实施消融步骤中，所述中空管内设置有化学管道和气体管道，所述注射头内设置有用于和化学管道连接的针头以及用于和气体管道连接的膨胀体，所述针头还与膨胀体连接，所述膨胀体膨胀后可推动所述针头伸出所述注射头；化学消融注射器对应包括化学注入体和气体注入体，分别连接化学管道和气体管道；在进行化学消融时，首先通过气体注入体向膨胀体内注入气体使膨胀体膨胀，进而使针头露出注射头；再通过化学注入体向针头注入化学药剂进行化学消融。Preferably, in the performing ablation step, a chemical pipeline and a gas pipeline are arranged in the hollow tube, a needle for connecting with the chemical pipeline and an expansion body for connecting with the gas pipeline are arranged in the injection head, and the The needle is also connected with the expansion body, and the expansion body can push the needle out of the injection head after expansion; the chemical ablation injector correspondingly includes a chemical injection body and a gas injection body, which are respectively connected to the chemical pipeline and the gas pipeline; When the injection is performed, gas is injected into the expansion body through the gas injection body to expand the expansion body, so that the needle is exposed to the injection head; and then chemical agents are injected into the needle through the chemical injection body for chemical ablation.

优选的，在所述实施消融步骤中，所述传输导管的隔离层内还设置有医用液流管，所述医用液流管一直延伸到所述射频消融电极，所述射频消融电极开设有导流孔，与所述医用液流管连通；所述射频消融控制器还包括医用液体输入体，由此可以向远端的射频消融电极注入医用液体。Preferably, in the step of performing ablation, a medical liquid flow tube is further arranged in the isolation layer of the transmission catheter, and the medical liquid flow tube extends all the way to the radio frequency ablation electrode, and the radio frequency ablation electrode is provided with a guide tube. The flow hole is in communication with the medical liquid flow tube; the radio frequency ablation controller further includes a medical liquid input body, so that the medical liquid can be injected into the radio frequency ablation electrode at the far end.

优选的，在所述实施消融步骤中，所述传输导管的隔离层内还设置有至少两根冷却液流管，所述冷却液流管一直延伸到所述射频消融电极，所述射频消融电极内部或者内侧面设置有冷却管网，所述冷却管网的两端分别与两根冷却液流管连接，冷却液经过两根冷却液流管和冷却管网构成冷却回路；射频消融控制器还包括冷却液输入体和冷却液输出体，分别连接一根冷却液流管，冷却液输入体向远端的射频消融电极连续注入冷却液，降低射频消融电极在消融过程中产生的高温，冷却液从冷却液输出体流出。Preferably, in the step of performing ablation, at least two cooling liquid flow pipes are further arranged in the isolation layer of the transmission catheter, and the cooling liquid flow pipes extend all the way to the radio frequency ablation electrode, and the radio frequency ablation electrode A cooling pipe network is arranged inside or on the inner side, the two ends of the cooling pipe network are respectively connected with two cooling liquid flow pipes, and the cooling liquid passes through the two cooling liquid flow pipes and the cooling pipe network to form a cooling circuit; the radio frequency ablation controller also It includes a cooling liquid input body and a cooling liquid output body, which are respectively connected to a cooling liquid flow pipe. The cooling liquid input body continuously injects cooling liquid into the distal radiofrequency ablation electrode to reduce the high temperature generated by the radiofrequency ablation electrode during the ablation process. out of the coolant outlet.

优选的，在所述放入装置和/或实施消融步骤中，还包括对放入传输导管和/或消融的过程进行实时监测和显示。Preferably, in the step of placing the device and/or performing the ablation, it also includes real-time monitoring and display of the process of placing the transmission catheter and/or the ablation.

本发明的有益效果是：本发明公开了一种射频与化学一体化消融方法，利用射频与化学一体化消融装置进行消融，包括步骤：放入装置，将射频与化学一体化消融装置的传输导管沿病人的血管放入，并使得传输导管远端设置的射频消融电极和注射头到达体内需要治疗的病灶部位；连接设备，将传输导管的近端接口连接射频消融控制器和化学消融注射器；实施消融，通过射频消融控制器和化学消融注射器对病灶部位进行射频消融和化学消融；结束处理，当射频消融和化学消融均结束后，取下射频消融控制器和化学消融注射器，再将传输导管从病人的血管中取出，完成消融。本发明实现了同时进行射频消融和化学消融，也可以分时进行射频消融和化学消融，有利于消融效果的改进和提升。The beneficial effects of the present invention are as follows: the present invention discloses a radio frequency and chemical integrated ablation method, which utilizes a radio frequency and chemical integrated ablation device for ablation, comprising the steps of: placing the device into the device, and connecting the transmission catheter of the radio frequency and chemical integrated ablation device Put it along the patient's blood vessel, and make the radiofrequency ablation electrode and injection head set at the distal end of the transmission catheter reach the lesion to be treated in the body; connect the device, and connect the proximal interface of the transmission catheter to the radiofrequency ablation controller and the chemical ablation injector; implement Ablation, perform radiofrequency ablation and chemical ablation on the lesion site through the radiofrequency ablation controller and chemical ablation injector; end the treatment, when both radiofrequency ablation and chemical ablation are completed, remove the radiofrequency ablation controller and chemical ablation injector, and then remove the transmission catheter from the It is removed from the patient's blood vessel and the ablation is done. The present invention realizes simultaneous radio frequency ablation and chemical ablation, and can also perform radio frequency ablation and chemical ablation in time division, which is beneficial to the improvement and promotion of the ablation effect.

附图说明Description of drawings

图1是根据本发明射频与化学一体化消融方法中一实施例的流程图；1 is a flow chart of an embodiment of a radiofrequency and chemical integrated ablation method according to the present invention;

图2是根据本发明射频与化学一体化消融方法中一实施例的传输导管和中空管组成示意图；2 is a schematic diagram of the composition of a transmission catheter and a hollow tube according to an embodiment of the radio frequency and chemical integrated ablation method of the present invention;

图3是根据本发明射频与化学一体化消融方法中一实施例的射频消融控制器组成示意图；3 is a schematic diagram of the composition of a radio frequency ablation controller according to an embodiment of the radio frequency and chemical integrated ablation method of the present invention;

图4是根据本发明射频与化学一体化消融方法中一实施例的化学消融控制器组成示意图；4 is a schematic diagram of the composition of a chemical ablation controller according to an embodiment of the radio frequency and chemical integrated ablation method of the present invention;

图5是根据本发明射频与化学一体化消融方法中实施例的传输导管和中空管的横截面示意图；5 is a schematic cross-sectional view of a transmission catheter and a hollow tube according to an embodiment of the radiofrequency and chemical integrated ablation method of the present invention;

图6是根据本发明射频与化学一体化消融方法中一实施例的针头收缩在注射头内的剖视图；6 is a cross-sectional view of the needle retracted in the injection head according to an embodiment of the radiofrequency and chemical integrated ablation method of the present invention;

图7是根据本发明射频与化学一体化消融方法中一实施例的针头伸出注射头的剖视图；7 is a cross-sectional view of the needle extending out of the injection head according to an embodiment of the radiofrequency and chemical integrated ablation method of the present invention;

图8是根据本发明射频与化学一体化消融方法中一实施例的膨胀体的横截面示意图；8 is a schematic cross-sectional view of an expansion body according to an embodiment of the radiofrequency and chemical integrated ablation method of the present invention;

图9是根据本发明射频与化学一体化消融方法中一实施例的近端接口示意图；9 is a schematic diagram of a proximal interface according to an embodiment of the integrated radiofrequency and chemical ablation method of the present invention;

图10是根据本发明射频与化学一体化消融方法中另一实施例的传输导管和中空管组成示意图；10 is a schematic diagram of the composition of a transmission catheter and a hollow tube according to another embodiment of the radio frequency and chemical integrated ablation method of the present invention;

图11是根据本发明射频与化学一体化消融方法中另一实施例的传输导管和中空管的横截面示意图；11 is a schematic cross-sectional view of a transmission catheter and a hollow tube according to another embodiment of the radiofrequency and chemical integrated ablation method of the present invention;

图12是根据本发明射频与化学一体化消融方法中另一实施例的射频消融电极的剖视图；12 is a cross-sectional view of a radiofrequency ablation electrode according to another embodiment of the radiofrequency and chemical integrated ablation method of the present invention;

图13是根据本发明射频与化学一体化消融方法中另一实施例的射频消融电极的横截面示意图；13 is a schematic cross-sectional view of a radiofrequency ablation electrode according to another embodiment of the radiofrequency and chemical integrated ablation method of the present invention;

图14是根据本发明射频与化学一体化消融方法中另一实施例的近端接口示意图；14 is a schematic diagram of a proximal interface according to another embodiment of the integrated radiofrequency and chemical ablation method of the present invention;

图15是根据本发明射频与化学一体化消融方法中另一实施例的射频消融控制器组成示意图。FIG. 15 is a schematic diagram of the composition of a radio frequency ablation controller according to another embodiment of the radio frequency and chemical integrated ablation method of the present invention.

具体实施方式Detailed ways

为了便于理解本发明，下面结合附图和具体实施例，对本发明进行更详细的说明。附图中给出了本发明的较佳的实施例。但是，本发明可以以许多不同的形式来实现，并不限于本说明书所描述的实施例。相反地，提供这些实施例的目的是使对本发明的公开内容的理解更加透彻全面。In order to facilitate understanding of the present invention, the present invention will be described in more detail below with reference to the accompanying drawings and specific embodiments. Preferred embodiments of the invention are shown in the accompanying drawings. However, the present invention may be embodied in many different forms and is not limited to the embodiments described in this specification. Rather, these embodiments are provided so that a thorough and complete understanding of the present disclosure is provided.

需要说明的是，除非另有定义，本说明书所使用的所有的技术和科学术语与属于本发明的技术领域的技术人员通常理解的含义相同。在本发明的说明书中所使用的术语只是为了描述具体的实施例的目的，不是用于限制本发明。本说明书所使用的术语“和/或”包括一个或多个相关的所列项目的任意的和所有的组合。It should be noted that, unless otherwise defined, all technical and scientific terms used in this specification have the same meaning as commonly understood by those skilled in the technical field of the present invention. The terms used in the description of the present invention are only for the purpose of describing specific embodiments, and are not used to limit the present invention. As used in this specification, the term "and/or" includes any and all combinations of one or more of the associated listed items.

如图1所示，一种射频与化学一体化消融方法，利用射频与化学一体化消融装置进行消融，包括步骤：As shown in Fig. 1, a radio frequency and chemical integrated ablation method, using a radio frequency and chemical integrated ablation device for ablation, includes the steps:

放入装置S1，将射频与化学一体化消融装置的传输导管沿病人的血管放入，并使得传输导管远端设置的射频消融电极和注射头到达体内需要治疗的病灶部位；Putting in the device S1, placing the transmission catheter of the integrated radio frequency and chemical ablation device along the patient's blood vessel, and making the radio frequency ablation electrode and the injection head set at the distal end of the transmission catheter reach the lesion to be treated in the body;

连接设备S2，将传输导管的近端接口连接射频消融控制器和化学消融注射器；Connect the device S2, and connect the proximal interface of the transmission catheter to the radiofrequency ablation controller and the chemical ablation injector;

实施消融S3，通过射频消融控制器和化学消融注射器对病灶部位进行射频消融和化学消融；Perform ablation S3, and perform radiofrequency ablation and chemical ablation on the lesion site through the radiofrequency ablation controller and the chemical ablation injector;

结束处理S4，当射频消融和化学消融均结束后，取下射频消融控制器和化学消融注射器，再将传输导管从病人的血管中取出，完成消融。The process S4 is ended. When both the radiofrequency ablation and the chemical ablation are completed, the radiofrequency ablation controller and the chemical ablation injector are removed, and the transmission catheter is taken out from the blood vessel of the patient to complete the ablation.

进一步的，在放入装置步骤S1中，传输导管内设置有连接射频消融控制器和射频消融电极的电连接体；传输导管还包括连接化学消融注射器和注射头的中空管。Further, in the step S1 of placing the device, the transmission catheter is provided with an electrical connector connecting the radiofrequency ablation controller and the radiofrequency ablation electrode; the transmission catheter also includes a hollow tube connected to the chemical ablation injector and the injection head.

具体的，结合图2至图4，射频与化学一体化消融装置包括传输导管1，在传输导管1的近端设置有用于连接射频消融控制器2或/和化学消融注射器3的近端接口4，在传输导管1的远端设置有用于射频消融的射频消融电极5和用于化学消融的注射头6。Specifically, with reference to FIGS. 2 to 4 , the integrated radio frequency and chemical ablation device includes atransmission catheter 1 , and aproximal end interface 4 for connecting the radio frequency ablation controller 2 or/and the chemical ablation injector 3 is provided at the proximal end of thetransmission catheter 1 . , a radiofrequency ablation electrode 5 for radio frequency ablation and aninjection head 6 for chemical ablation are arranged at the distal end of thetransmission catheter 1 .

需要说明，这里的远端是指靠近需要一体化消融处理的病灶组织，近端则是指在人体外部靠近射频消融和化学消融设备的一端。It should be noted that the distal end here refers to the end that is close to the lesion tissue that needs integrated ablation treatment, and the proximal end refers to the end that is close to the radiofrequency ablation and chemical ablation equipment outside the human body.

优选的，由于传输导管是通过血管逐步深入放置到病灶组织的，因此传输导管的截面口径是小于对应的血管直径的。例如，通过肾动脉对肾脏组织进行这种一体化消融处理。Preferably, since the delivery catheter is gradually placed deep into the lesion tissue through the blood vessel, the cross-sectional diameter of the delivery catheter is smaller than the diameter of the corresponding blood vessel. For example, this integrated ablation of renal tissue is performed through the renal artery.

结合图5，图5为传输导管1和中空管8的横截面示意图。传输导管1内设置有连接射频消融控制器2和射频消融电极5的电连接体7。In conjunction with FIG. 5 , FIG. 5 is a schematic cross-sectional view of thetransmission conduit 1 and thehollow tube 8 . Thetransmission catheter 1 is provided with an electrical connectingbody 7 connecting the radio frequency ablation controller 2 and the radiofrequency ablation electrode 5 .

优选的，电连接体7包括两根独立的连接线缆，正极连接线缆71和负极连接线缆72。两根连接线缆分别连接射频消融电极5的正负两个接线端。两根连接线缆中至少有一根连接线缆的外层包裹有绝缘层9，避免这两根连接线缆在包覆层101的内部直接相互接触而短路。Preferably, the electrical connectingbody 7 includes two independent connecting cables, a positive connectingcable 71 and a negative connectingcable 72 . The two connection cables are respectively connected to the positive and negative terminals of theradiofrequency ablation electrode 5 . The outer layer of at least one of the two connecting cables is wrapped with an insulating layer 9 to prevent the two connecting cables from directly contacting each other inside thecovering layer 101 and short-circuiting.

进一步的，传输导管1还包括连接化学消融注射器3和注射头6的中空管8，化学消融注射器3通过中空管8向注射头6注射化学药剂对病灶部位进行化学消融。Further, thedelivery catheter 1 further includes ahollow tube 8 connecting the chemical ablation injector 3 and theinjection head 6 , and the chemical ablation injector 3 injects a chemical agent into theinjection head 6 through thehollow tube 8 to chemically ablate the lesion site.

可以看出，在图5中，中空管8设置在传输导管1外部，传输导管1的外层为包覆层101，电连接体7内封在包覆层101的内部，包覆层101的表面还与中空管8的外层表面结合为一体，由此形成传输导管1的外表面和中空管8的外表面结合为一体的双管道结构体。使得射频消融和化学消融既可以同时进行又可以分时进行。It can be seen that, in FIG. 5 , thehollow tube 8 is arranged outside thetransmission conduit 1 , the outer layer of thetransmission conduit 1 is thecladding layer 101 , theelectrical connector 7 is enclosed inside thecladding layer 101 , and thecladding layer 101 The surface of thehollow tube 8 is also integrated with the outer surface of thehollow tube 8, thereby forming a double-pipe structure in which the outer surface of thetransmission conduit 1 and the outer surface of thehollow tube 8 are integrated into one. So that radiofrequency ablation and chemical ablation can be performed simultaneously or in time.

优选的，包覆层101的内部还设置有弧面状的硬质弹性金属条10，并且沿传输导管1的轴向延伸，由此可以提高整个传输导管1的韧性和刚度，增强抗弯曲性能。这样有利于传输导管在血管内逐步放置，避免传输导管因为硬度不够而弯曲或者难以推动。Preferably, cambered hard elastic metal strips 10 are also arranged inside thecoating layer 101 and extend along the axial direction of thetransmission conduit 1 , thereby improving the toughness and rigidity of theentire transmission conduit 1 and enhancing the bending resistance. . This facilitates the gradual placement of the delivery catheter in the blood vessel, and prevents the delivery catheter from being bent or difficult to push due to insufficient rigidity.

优选的，在实施消融步骤S4中，所述中空管内设置有化学管道和气体管道，具体的是在化学消融时，需要将注射头6的针头露出，而并不是一开始就露出针头，这是为了避免注射头6在进入血管时，其针头划伤血管。也就是说在步骤S1中，注射头6是内藏起来的。Preferably, in performing the ablation step S4, the hollow tube is provided with a chemical pipeline and a gas pipeline. Specifically, during chemical ablation, the needle of theinjection head 6 needs to be exposed, rather than the needle exposed at the beginning, which is In order to prevent the needle of theinjection head 6 from scratching the blood vessel when it enters the blood vessel. That is to say, in step S1, theinjection head 6 is hidden.

具体的，结合图6和图7。图6为针头收缩在注射头内的剖视图，图7为针头伸出注射头的剖视图。在中空管8内设置有化学管道81和气体管道82。注射头6内设置有用于和化学管道81连接的针头61以及用于和气体管道82连接的膨胀体62，针头61还与膨胀体62连接，膨胀体62膨胀后可推动针头61伸出注射头6。Specifically, refer to FIG. 6 and FIG. 7 . FIG. 6 is a cross-sectional view of the needle retracted in the injection head, and FIG. 7 is a cross-sectional view of the needle extending out of the injection head. Achemical pipe 81 and agas pipe 82 are provided in thehollow pipe 8 . Theinjection head 6 is provided with aneedle 61 for connecting with thechemical pipeline 81 and anexpansion body 62 for connecting with thegas pipeline 82. Theneedle 61 is also connected with theexpansion body 62, and theexpansion body 62 can push theneedle 61 out of the injection head after expansion. 6.

当没有气体通过气体管道82注入到膨胀体62时，膨胀体62为收缩状态，并且与射频消融电极5的外表面并不接触。这样，当射频消融电极5进行射频消融时产生的热量并不会影响到膨胀体62。优选的，当向膨胀体62注入气体后，膨胀体62向前膨胀延伸并将针头61从注射头6的圆孔66推出。When no gas is injected into theinflation body 62 through thegas conduit 82 , theinflation body 62 is in a contracted state and does not contact the outer surface of theradiofrequency ablation electrode 5 . In this way, the heat generated when theradiofrequency ablation electrode 5 performs radiofrequency ablation will not affect theexpansion body 62 . Preferably, after gas is injected into theinflation body 62 , theinflation body 62 expands and extends forward and pushes theneedle 61 out of thecircular hole 66 of theinjection head 6 .

优选的，膨胀体62通过固定架64进行固定，固定架64的横截面呈凹形，包括底壁和侧壁。膨胀体62远离针头61的一端固定在固定架64的底壁上，靠近针头61的一端连接移动板63。在移动板63上下两侧设置有凸块631，在固定架64的侧壁上对应设置有滑槽65，凸块631位于滑槽65内，可在滑槽65内滑动。Preferably, theexpansion body 62 is fixed by a fixingframe 64, and the cross-section of the fixingframe 64 is concave, including a bottom wall and a side wall. One end of theexpansion body 62 away from theneedle 61 is fixed on the bottom wall of the fixingframe 64 , and one end close to theneedle 61 is connected to the movingplate 63 . Protrudingblocks 631 are provided on the upper and lower sides of the movingplate 63 , and slidinggrooves 65 are correspondingly provided on the side walls of the fixingframe 64 .

优选的，结合图8，膨胀体62的横截面为环形，具有一个供化学管道81穿过的过孔621，化学管道81还穿过移动板63与固定在移动板63上的针头61连通。Preferably, referring to FIG. 8 , theinflatable body 62 is annular in cross section and has a throughhole 621 for thechemical pipeline 81 to pass through.

优选的，如图9所示，近端接口4包括用于连接传输导管1内的电连接体7的射频消融近端接口，射频消融近端接口包括正极接口41和负极接口42。射频消融近端接口用于和图2中的射频消融控制器2电连接。以及用于密闭连接中空管8的化学消融近端接口，化学消融近端接口包括化学管道接口43和气体管道接口44，通过图3中的化学总接口33与化学消融注射器3连接。化学消融注射器3包括化学注入体31和气体注入体32，分别对应与化学管道接口43和气体管道接口44连通。Preferably, as shown in FIG. 9 , theproximal interface 4 includes a radiofrequency ablation proximal interface for connecting theelectrical connection body 7 in thetransmission catheter 1 , and the radiofrequency ablation proximal interface includes apositive interface 41 and anegative interface 42 . The radiofrequency ablation proximal interface is used for electrical connection with the radiofrequency ablation controller 2 in FIG. 2 . And the chemical ablation proximal interface for sealingly connecting thehollow tube 8, the chemical ablation proximal interface includes achemical pipeline interface 43 and agas pipeline interface 44, and is connected to the chemical ablation injector 3 through the chemical general interface 33 in FIG. 3 . The chemical ablation injector 3 includes achemical injection body 31 and a gas injection body 32, which are communicated with thechemical pipeline interface 43 and thegas pipeline interface 44, respectively.

在进行射频消融之前，即在连接设备步骤S2中，将射频消融控制器2连接近端接口4上的正极接口41和负极接口42，然后在实施消融步骤S3中，可以经过传输导管1内的电连接体7控制射频消融电极5释放射频消融电流对病灶部位进行射频消融。Before performing radiofrequency ablation, that is, in the step S2 of connecting the device, the radiofrequency ablation controller 2 is connected to thepositive port 41 and thenegative port 42 on theproximal port 4, and then in the step S3 of performing the ablation, the radiofrequency ablation controller 2 can pass through the The electrical connectingbody 7 controls theradiofrequency ablation electrode 5 to release the radiofrequency ablation current to perform radiofrequency ablation of the lesion site.

在进行化学消融之前，即在连接设备步骤S2中，将化学消融注射器3连接近端接口4。具体的，化学注入体31连接化学管道接口43，气体注入体32对应与气体管道接口44连接；然后在实施消融步骤S3中，首先气体注入体32通过气体管道82向膨胀体62内注入气体使膨胀体62膨胀，推动移动板63向前移动，进而使针头61露出注射头6。气体注入体32在进行充气时，压力可控。然后化学注入体61通过化学管道81向针头61注射化学药剂对病灶部位进行化学消融。Before performing chemical ablation, that is, in the step S2 of connecting the device, the chemical ablation syringe 3 is connected to theproximal port 4 . Specifically, thechemical injection body 31 is connected to thechemical pipeline interface 43, and the gas injection body 32 is correspondingly connected to thegas pipeline interface 44; then in the ablation step S3, first the gas injection body 32 injects gas into theexpansion body 62 through thegas pipeline 82 to make Theexpansion body 62 expands and pushes the movingplate 63 to move forward, thereby exposing theneedle 61 to theinjection head 6 . When the gas injection body 32 is inflated, the pressure is controllable. Then, thechemical injector 61 injects a chemical agent into theneedle 61 through thechemical channel 81 to chemically ablate the lesion site.

优选的，在结束处理步骤S4中，完成化学消融后，通过气体注入体32吸气，使膨胀体62收缩，进而使移动板带动针头61收缩在注射头6内。Preferably, in the end processing step S4 , after the chemical ablation is completed, inhale through the gas injector 32 to contract theinflation body 62 , and then the moving plate drives theneedle 61 to contract in theinjection head 6 .

可以看出，射频消融近端接口和化学消融近端接口是两个独立的接口，又分别连接射频消融控制器2和化学消融注射器3。由此可以使得射频消融和化学消融既可以分别独立进行，比如先进行射频消融，再进行化学消融，但是这种分别独立进行消融的方式并不需要将这种一体化的通道连接管取出来，而是在保持传输导管和中空管沿血管插入人体后不取出的情况下，先进行射频消融再进行化学消融，或者先进行化学消融再进行射频消融。也可以根据治疗需要使得这两种消融方式同时或同步进行，就是一边进行射频消融，一边进行化学消融，使得这两种方式得以同步实施。It can be seen that the radiofrequency ablation proximal interface and the chemical ablation proximal interface are two independent interfaces, which are connected to the radiofrequency ablation controller 2 and the chemical ablation injector 3 respectively. Therefore, both radiofrequency ablation and chemical ablation can be performed independently, for example, radiofrequency ablation is performed first, and then chemical ablation is performed. Instead, while the transmission catheter and the hollow tube are not taken out after being inserted into the human body along the blood vessel, radiofrequency ablation is performed first and then chemical ablation is performed, or chemical ablation is performed first and then radiofrequency ablation is performed. The two ablation methods can also be performed simultaneously or synchronously according to treatment needs, that is, performing radiofrequency ablation while performing chemical ablation, so that the two methods can be performed simultaneously.

通过上述实施例可以看出，在连接设备步骤S2中，传输导管1的近端接口4可同时连接射频消融控制器2和化学消融注射器3；It can be seen from the above embodiment that in the step S2 of connecting the device, theproximal interface 4 of thetransmission catheter 1 can be connected to the radiofrequency ablation controller 2 and the chemical ablation injector 3 at the same time;

在实施消融步骤S3中，射频消融和化学消融可同时进行或射频消融和化学消融分时进行。当需要射频消融和化学消融同时进行时，传输导管1的近端接口4连接射频消融控制器2和化学消融注射器3，由射频消融控制器2和化学消融注射器3同时并分别进行射频消融和化学消融。当需要射频消融和化学消融分时进行时，传输导管1的近端接口4连接射频消融控制器2或化学消融注射器3，对应进行射频消融或化学消融。In performing the ablation step S3, the radiofrequency ablation and the chemical ablation may be performed simultaneously or the radiofrequency ablation and the chemical ablation may be performed at different times. When both radiofrequency ablation and chemical ablation need to be performed at the same time, theproximal interface 4 of thetransmission catheter 1 is connected to the radiofrequency ablation controller 2 and the chemical ablation injector 3, and the radiofrequency ablation controller 2 and the chemical ablation injector 3 simultaneously and respectively perform radiofrequency ablation and chemical ablation. ablation. When radiofrequency ablation and chemical ablation need to be performed at different times, theproximal interface 4 of thetransmission catheter 1 is connected to the radiofrequency ablation controller 2 or the chemical ablation injector 3 to perform radiofrequency ablation or chemical ablation correspondingly.

优选的，作为射频与化学一体化消融装置的另一实施例。结合图10和图11。中空管8设置在传输导管1内部，传输导管1的外层为包覆层101，在中空管8套装在包覆层101的内部，在包覆层101与中空管8之间设置有隔离层11，电连接体7设置在隔离层11。由此形成中空管8和电连接体7套装在传输导管1内部的一体化结构体。这里的隔离层11可以是软质材料填充。Preferably, as another embodiment of the radio frequency and chemical integrated ablation device. 10 and 11 are combined. Thehollow tube 8 is arranged inside thetransmission conduit 1 , the outer layer of thetransmission conduit 1 is acoating layer 101 , thehollow tube 8 is sheathed inside thecoating layer 101 , and is arranged between thecoating layer 101 and thehollow tube 8 There is anisolation layer 11 , and theelectrical connection body 7 is arranged on theisolation layer 11 . Thus, an integrated structure in which thehollow tube 8 and the electrical connectingbody 7 are sheathed inside thetransmission conduit 1 is formed. Theisolation layer 11 here may be filled with a soft material.

优选的，电连接体7包括两根独立的连接线缆，分别为正极连接线缆71和负极连接线缆72。两根连接线缆分别连接射频消融电极5的正负两极。Preferably, theelectrical connector 7 includes two independent connecting cables, which are a positive connectingcable 71 and a negative connectingcable 72 respectively. The two connecting cables are respectively connected to the positive and negative poles of theradiofrequency ablation electrode 5 .

优选的，在隔离层11也设置有弧面状的硬质弹性金属条10，并且沿传输导管1的轴向延伸，由此可以提高整个传输导管1的韧性和刚度，增强抗弯曲性能。Preferably, arc-shaped hard elastic metal strips 10 are also provided on theisolation layer 11 and extend along the axial direction of thetransmission conduit 1 , thereby improving the toughness and rigidity of theentire transmission conduit 1 and enhancing the bending resistance.

优选的，结合图12，图12为射频消融电极5的剖视图。在隔离层11内还设置有医用液流管12，医用液流管12一直延伸到射频消融电极5，射频消融电极5开设有导流孔51，并且与医用液流管12连通，用于射频消融时注射生理盐水或其他用于消炎、杀菌以及抗病毒的液体药物。在图11中，医用液流管12具有两个。Preferably, with reference to FIG. 12 , FIG. 12 is a cross-sectional view of theradiofrequency ablation electrode 5 . A medicalliquid flow tube 12 is also arranged in theisolation layer 11. The medicalliquid flow tube 12 extends to the radiofrequency ablation electrode 5. The radiofrequency ablation electrode 5 is provided with adiversion hole 51 and communicates with the medicalliquid flow tube 12 for radio frequency ablation. Inject normal saline or other liquid medicines for anti-inflammatory, bactericidal, and antiviral purposes during ablation. In FIG. 11 , there are two medicalfluid flow tubes 12 .

因此，在实施消融步骤S3中，当实施射频消融时，可以注入医用液体，起到辅助进行射频消融的目的。Therefore, in performing the ablation step S3, when performing the radiofrequency ablation, a medical liquid may be injected to assist the radiofrequency ablation.

优选的，结合图13。图13为射频消融电极5的横截面示意图。在隔离层11内还设置有至少两根冷却液流管13，冷却液流管13一直延伸到射频消融电极5，射频消融电极5内部或者内侧面设置有冷却管网52，冷却管网52的两端(53和54)分别与两根冷却液流管13连通，冷却液经过两根冷却液流管13和冷却管网52构成冷却回路，通过向冷却液流管13注入冷却液对射频消融电极5降温。Preferably, refer to FIG. 13 . FIG. 13 is a schematic cross-sectional view of theradiofrequency ablation electrode 5 . At least two coolingliquid flow pipes 13 are also arranged in theisolation layer 11. The coolingliquid flow pipes 13 extend to the radiofrequency ablation electrode 5. A coolingpipe network 52 is arranged inside or on the inner side of the radiofrequency ablation electrode 5. The two ends (53 and 54) are respectively connected with the two coolingliquid flow pipes 13. The cooling liquid passes through the two coolingliquid flow pipes 13 and thecooling pipe network 52 to form a cooling circuit.Electrode 5 cools down.

因此，在实施消融步骤S3中，当实施射频消融时，可以循环注入和回流冷却液体，起到对射频消融电极5降温的目的。Therefore, in performing the ablation step S3 , when performing the radiofrequency ablation, the cooling liquid may be injected and returned cyclically, so as to achieve the purpose of cooling theradiofrequency ablation electrode 5 .

化学消融注射器对应包括化学注入体和气体注入体，分别连接化学管道和气体管道；在进行化学消融时，首先通过气体注入体向膨胀体内注入气体使膨胀体膨胀，进而使针头露出注射头；再通过化学注入体向针头注入化学药剂进行化学消融。The chemical ablation injector correspondingly includes a chemical injection body and a gas injection body, which are respectively connected to the chemical pipeline and the gas pipeline; during chemical ablation, firstly, gas is injected into the expansion body through the gas injection body to expand the expansion body, and then the needle is exposed to the injection head; Chemical ablation is performed by injecting chemical agents into the needle through a chemical infuser.

优选的，在结合图11和图12。在中空管8内设置有化学管道81和气体管道82。射频消融电极5呈空心圆柱体状，在射频消融电极5的内部设置有容纳注射头6的腔体56，注射头6的前端相对图6和图7中的尖端结构变为平面结构，便于安装在腔体56内。腔体56自射频消融电极5的端部中心朝向射频消融电极5的头部延伸，射频消融电极5的头部为圆弧状结构，在其圆弧中心开设有注射孔55，注射孔55与腔体56连通。Preferably, in conjunction with FIG. 11 and FIG. 12 . Achemical pipe 81 and agas pipe 82 are provided in thehollow pipe 8 . The radiofrequency ablation electrode 5 is in the shape of a hollow cylinder, and acavity 56 for accommodating theinjection head 6 is arranged inside the radiofrequency ablation electrode 5. The front end of theinjection head 6 becomes a plane structure relative to the tip structure in FIGS. 6 and 7, which is convenient for installation. withincavity 56 . Thecavity 56 extends from the center of the end of theradiofrequency ablation electrode 5 toward the head of theradiofrequency ablation electrode 5. The head of theradiofrequency ablation electrode 5 is an arc-shaped structure, and aninjection hole 55 is opened in the center of the arc. Thecavity 56 communicates.

注射头6设置在该腔体56内，在注射头6内设置有用于和化学管道81连接的针头61以及用于和气体管道82连接的膨胀体62，针头61还与膨胀体62连接，膨胀体62膨胀后可推动针头61伸出注射头6，同时也从注射孔55内伸出。Theinjection head 6 is arranged in thecavity 56, and theinjection head 6 is provided with aneedle 61 for connecting with thechemical pipeline 81 and anexpansion body 62 for connecting with thegas pipeline 82, and theneedle 61 is also connected with theexpansion body 62. After thebody 62 is inflated, theneedle 61 can be pushed out of theinjection head 6 and also out of theinjection hole 55 .

当没有气体通过气体管道82注入到膨胀体62时，膨胀体62为收缩状态，并且与射频消融电极5的外表面并不接触。这样，当射频消融电极5进行射频消融时产生的热量并不会影响到膨胀体62。当气体通过气体管道82注入到膨胀体62后，膨胀体62膨胀向前推动针头61伸出注射孔55，此时可通过化学管道81向针头61注射注射化学药剂进行消融。化学消融后，气体管道82向外排气时，膨胀体62体积变小拉动针头61收缩在射频消融电极5内。When no gas is injected into theinflation body 62 through thegas conduit 82 , theinflation body 62 is in a contracted state and does not contact the outer surface of theradiofrequency ablation electrode 5 . In this way, the heat generated when theradiofrequency ablation electrode 5 performs radiofrequency ablation will not affect theexpansion body 62 . After the gas is injected into theinflation body 62 through thegas pipeline 82 , theinflation body 62 expands and pushes theneedle 61 forward and out of theinjection hole 55 . After chemical ablation, when thegas pipeline 82 is exhausted to the outside, the volume of theinflatable body 62 becomes smaller, and theneedle 61 is pulled to shrink into theradiofrequency ablation electrode 5 .

优选的，在图2所示的实施例中，射频消融电极5上也开设有导流孔51和冷却管网52，在传输导管1内对应设置有医用液流管12和冷却液流管13。Preferably, in the embodiment shown in FIG. 2 , theRF ablation electrode 5 is also provided with aguide hole 51 and acooling pipe network 52 , and a medicalliquid flow pipe 12 and a coolingliquid flow pipe 13 are correspondingly provided in thetransmission conduit 1 . .

优选的，如图14所示。近端接口4包括两个射频电极端，分别与隔离层11中的两根独立的连接线缆电连接。两个射频电极端分别设置在两个射频电极孔内，即射频正极孔41和射频负极孔42内。Preferably, as shown in Figure 14. Theproximal interface 4 includes two radio frequency electrode ends, which are respectively electrically connected to two independent connection cables in theisolation layer 11 . The two radio frequency electrode ends are respectively disposed in the two radio frequency electrode holes, namely the radio frequencypositive electrode hole 41 and the radio frequencynegative electrode hole 42 .

如图15所示。优选的，在步骤连接设备S2中，射频消融控制器2包括两个可以分别插入两个射频电极孔内的射频电极柱，即射频正极电极柱和射频负极电极柱。两个射频电极柱设置在射频总接口26上。As shown in Figure 15. Preferably, in the step of connecting the device S2, the radio frequency ablation controller 2 includes two radio frequency electrode posts that can be respectively inserted into the two radio frequency electrode holes, namely the radio frequency positive electrode post and the radio frequency negative electrode post. Two radio frequency electrode posts are arranged on the radio frequency general interface 26 .

优选的，两个射频电极柱和对应的射频电极孔具有不同的横截面，由此可以防止误插，例如一个射频电极柱和对应的射频电极孔的截面是正方形，另一个射频电极柱和对应的射频电极孔的截面是圆形。优选的，在射频电极孔设置有弹簧，由此可以使得插接时个射频电极柱更加紧密的与射频电极孔内的射频电极端电连接，确保了电连接的可靠性。Preferably, the two RF electrode posts and the corresponding RF electrode holes have different cross-sections, thereby preventing mis-insertion. For example, the cross-sections of one RF electrode column and the corresponding RF electrode hole are square, and the other RF electrode column and the corresponding RF electrode hole are square. The cross section of the RF electrode hole is circular. Preferably, the radio frequency electrode hole is provided with a spring, so that each radio frequency electrode post can be more closely electrically connected to the radio frequency electrode end in the radio frequency electrode hole when plugged, thereby ensuring the reliability of the electrical connection.

在进行射频消融时，由射频消融控制器2中的射频消融控制体21与两个射频电极孔内的射频电极柱电连接，并通过射频消融控制体21控制通断电以及射频消融时的电流大小。During radio frequency ablation, the radio frequencyablation control body 21 in the radio frequency ablation controller 2 is electrically connected to the radio frequency electrode posts in the two radio frequency electrode holes, and the radio frequencyablation control body 21 controls the power on and off and the current during radio frequency ablation size.

优选的，近端接口4还包括医用液体输入口45，对应与隔离层11内的医用液流管12密闭连接。优选的，射频消融控制器2对应包括医用液体输入体22，插入到对应的医用液体输入口45，由此可以向远端的射频消融电极5注入医用液体。Preferably, theproximal interface 4 further includes a medicalliquid input port 45 , which is correspondingly tightly connected with the medicalliquid flow tube 12 in theisolation layer 11 . Preferably, the radio frequency ablation controller 2 correspondingly includes a medicalliquid input body 22 , which is inserted into the corresponding medicalliquid input port 45 , so that the medical liquid can be injected into the distal radiofrequency ablation electrode 5 .

优选的，近端接口4还包括冷却液输入口46和冷却液输出口47，分别对应与隔离层11内的两根液流管密闭连接。射频消融控制器2对应包括冷却液输入体23和冷却液输出体24，分别插入到对应的冷却液输入口46和冷却液输出口47。由此可以使得从射频消融控制器2向远端的射频消融电极5连续注入冷却液，降低射频消融电极5在消融过程中产生的高温。冷却液从冷却液输入体注入，从冷却液输出体流出。Preferably, theproximal interface 4 further includes a coolingliquid input port 46 and a coolingliquid output port 47 , which are respectively tightly connected with the two liquid flow pipes in theisolation layer 11 . The radiofrequency ablation controller 2 correspondingly includes a coolingliquid input body 23 and a coolingliquid output body 24, which are inserted into the corresponding coolingliquid input port 46 and coolingliquid output port 47, respectively. In this way, cooling liquid can be continuously injected from the radio frequency ablation controller 2 to the distal radiofrequency ablation electrode 5 to reduce the high temperature generated by the radiofrequency ablation electrode 5 during the ablation process. The coolant is injected from the coolant input body and flows out from the coolant output body.

从图14可以看出，近端接口4呈阶梯状，包括第一阶梯接口401和第二阶梯接口402。其中，射频正极孔41和射频负极孔42、医用液体输入口45、冷却液输入口46和冷却液输出口47都设置在第一阶梯接口401上，第一阶梯接口401与射频消融控制器2的射频总接口26对应配合连接。第二阶梯接口402用于和化学消融注射器3连接。As can be seen from FIG. 14 , theproximal interface 4 is stepped, including a first steppedinterface 401 and a second steppedinterface 402 . Among them, the RFpositive hole 41 and the RFnegative hole 42 , the medicalliquid input port 45 , the coolingliquid input port 46 and the coolingliquid output port 47 are all arranged on the first steppedinterface 401 , and the first steppedinterface 401 is connected to the radio frequency ablation controller 2 . The radio frequency general interface 26 of the corresponding mating connection. The second steppedinterface 402 is used to connect with the chemical ablation injector 3 .

优选的，结合图4和图14。近端接口4包括化学注入口43，化学注入口43与中空管8密闭连接，具体的，化学注入口43是与中空管8种的化学管道81密闭连接的。化学消融注射器3对应包括化学注入体31，插入到化学注入口43后可以由此向中空管8以致远端的注射体6注入化学治疗药物。Preferably, combine FIG. 4 and FIG. 14 . Theproximal interface 4 includes achemical injection port 43 , and thechemical injection port 43 is hermetically connected to thehollow tube 8 . Specifically, thechemical injection port 43 is hermetically connected to the eight types ofchemical pipes 81 of the hollow tube. The chemical ablation syringe 3 correspondingly includes achemical injection body 31 , which can inject chemotherapeutic drugs into thehollow tube 8 and thedistal injection body 6 after being inserted into thechemical injection port 43 .

近端接口4还包括气体注入口44，化学消融注射器3还包括气体注入体32，插入到气体注入口44后可以由此向气体管道82充气和放气。化学消融注射器3的化学总接口33与第二阶梯接口402对应连接。Theproximal port 4 further includes agas injection port 44, and the chemical ablation injector 3 further includes a gas injection body 32, which can inflate and deflate thegas pipeline 82 after being inserted into thegas injection port 44. The chemical general interface 33 of the chemical ablation injector 3 is correspondingly connected to the second steppedinterface 402 .

由此可见，这里的近端接口是一个公共接口，在连接设备步骤S2中，传输导管1的近端接口可选择地连接射频消融控制器或化学消融注射器；使得在实施消融步骤S3中，射频消融和化学消融分时进行。It can be seen that the proximal interface here is a public interface. In the step S2 of connecting the device, the proximal interface of thetransmission catheter 1 can be selectively connected to the radio frequency ablation controller or the chemical ablation injector; so that in the ablation step S3, the radio frequency Ablation and chemical ablation are performed in time.

近端接口可以分别与射频消融控制器和化学消融注射器连接，并且还进一步通过对应的接口连接对应的输入体，相互之间隔离独立，不会发生混淆而插错，具有专门的接口连接专用输入体，进而实现专用的功能。使得射频消融和化学消融可以分时进行，传输导管的近端接口连接射频消融控制器或化学消融注射器，对应进行射频消融或化学消融。例如，对于化学消融注射器，所述近端接口只有一个与之配合连接的化学注入口，该化学注入口与前述的冷却液输入口、冷却液输出口、医用液体输入口、射频电极端等设置在不同的位置，因而相互不会影响，可以分开独立使用。因此，这里的射频消融控制器和化学消融注射器是分时使用的，通常是先接入射频消融控制器进行射频消融，完成以后，解除射频消融控制器与近端接口的连接，然后再把化学消融注射器与近端接口的连接，进而再进行化学消融。The proximal interface can be connected to the radio frequency ablation controller and the chemical ablation injector respectively, and is further connected to the corresponding input body through the corresponding interface, which is isolated and independent from each other, and will not be confused and inserted wrongly. It has a special interface to connect a dedicated input body, and then realize the dedicated function. The radio frequency ablation and the chemical ablation can be performed in time, and the proximal interface of the transmission catheter is connected to the radio frequency ablation controller or the chemical ablation injector, and the radio frequency ablation or the chemical ablation is performed correspondingly. For example, for a chemical ablation syringe, the proximal interface has only one chemical injection port that is matched and connected to it. In different positions, so they will not affect each other and can be used independently. Therefore, the radiofrequency ablation controller and the chemical ablation injector are used in a time-sharing manner. Usually, the radiofrequency ablation controller is connected to the radiofrequency ablation controller for radiofrequency ablation. After completion, the connection between the radiofrequency ablation controller and the proximal interface is released, and then the chemical The connection of the ablation syringe to the proximal interface, and then chemical ablation is performed.

优选的，在实施消融步骤中，还包括对消融的过程进行实时监控和显示。例如可以通过数字减影血管造影(DSA，digital subtraction angiography)、光学相关断层扫描OCT、血管内超声(IVUS，intravenous ultrasound)等专用显示设备对射频消融电极或注射头是否到达病灶部位进行判断，也可以对消融是否成功进行判断。并且还可以保留消融过程中的监控视频，留作后期的对比参考。Preferably, in the step of performing the ablation, it also includes monitoring and displaying the ablation process in real time. For example, digital subtraction angiography (DSA, digital subtraction angiography), optical correlation tomography (OCT), intravascular ultrasound (IVUS, intravenous ultrasound) and other special display equipment can be used to determine whether the radiofrequency ablation electrode or injection head has reached the lesion site, and also A determination can be made as to whether the ablation was successful. In addition, the surveillance video during the ablation process can also be retained for later comparison reference.

由此可见，本发明公开了一种射频与化学一体化消融方法，利用射频与化学一体化消融装置进行消融，包括步骤：放入装置，将射频与化学一体化消融装置的传输导管沿病人的血管放入，并使得传输导管远端设置的射频消融电极和注射头到达体内需要治疗的病灶部位；连接设备，将传输导管的近端接口连接射频消融控制器和化学消融注射器；实施消融，通过射频消融控制器和化学消融注射器对病灶部位进行射频消融和化学消融；结束处理，当射频消融和化学消融均结束后，取下射频消融控制器和化学消融注射器，再将传输导管从病人的血管中取出，完成消融。本发明实现了同时进行射频消融和化学消融，也可以分时进行射频消融和化学消融，有利于消融效果的改进和提升。It can be seen that the present invention discloses a radio frequency and chemical integrated ablation method, which utilizes a radio frequency and chemical integrated ablation device for ablation, including the steps of: placing the device, and placing the transmission catheter of the radio frequency and chemical integrated ablation device along the patient's body. The blood vessel is placed, and the radiofrequency ablation electrode and the injection head set at the distal end of the transmission catheter reach the lesion that needs to be treated in the body; the device is connected, and the proximal interface of the transmission catheter is connected to the radiofrequency ablation controller and the chemical ablation syringe; the ablation is performed by The radiofrequency ablation controller and the chemical ablation injector are used to perform radiofrequency ablation and chemical ablation on the lesion site; after the treatment is completed, when both the radiofrequency ablation and the chemical ablation are completed, the radiofrequency ablation controller and the chemical ablation injector are removed, and the transmission catheter is removed from the patient's blood vessel. removed, and the ablation was completed. The present invention realizes simultaneous radio frequency ablation and chemical ablation, and can also perform radio frequency ablation and chemical ablation in time division, which is beneficial to the improvement and promotion of the ablation effect.

以上所述仅为本发明的实施例，并非因此限制本发明的专利范围，凡是利用本发明说明书及附图内容所作的等效结构变换，或直接或间接运用在其他相关的技术领域，均同理包括在本发明的专利保护范围内。The above descriptions are only the embodiments of the present invention, and are not intended to limit the scope of the patent of the present invention. Any equivalent structural transformation made by using the contents of the description and drawings of the present invention, or directly or indirectly applied to other related technical fields, are the same as The principles are included in the scope of patent protection of the present invention.