CN111721956A - A fully automatic biochemical analyzer liquid circuit system - Google Patents

Abstract

Translated fromChinese

本发明公开了一种全自动生化分析仪液路系统，加水模块包括储水单元和与储水单元连接的加压单元，加样清洗模块包括加样针清洗单元、试剂针清洗单元和搅拌棒清洗单元，反应杯清洗模块包括反应杯清洗液路单元和双头负压泵，反应杯清洗液路单元和双头负压泵均与反应杯内部相连通，废液收集模块包括废液收集单元和与废液收集单元相连通的试剂冷藏室冷凝管路，加样针清洗单元、试剂针清洗单元和搅拌棒清洗单元的出水端均与试剂冷藏室冷凝管路相连通，双头负压泵的出水端与废液收集单元相连通。本发明充分利用器件本身性能和常用物理原理来实现机器功能需求，简化结构和控制，从而提高系统稳定性和大幅度降低成本。

The invention discloses a liquid circuit system of an automatic biochemical analyzer. A water adding module includes a water storage unit and a pressurizing unit connected with the water storage unit, and the sample adding cleaning module includes a sample adding needle cleaning unit, a reagent needle cleaning unit and a stirring rod. Cleaning unit, the cuvette cleaning module includes a cuvette cleaning liquid circuit unit and a double-head negative pressure pump, the cuvette cleaning liquid circuit unit and the double-headed negative pressure pump are both connected with the inside of the cuvette, and the waste liquid collection module includes a waste liquid collection unit It is connected with the condensation pipeline of the reagent refrigerator compartment connected with the waste liquid collection unit. The water outlet ends of the sample needle cleaning unit, the reagent needle cleaning unit and the stirring bar cleaning unit are all connected with the condensation pipeline of the reagent refrigerator compartment. The double-head negative pressure pump The water outlet end is communicated with the waste liquid collection unit. The invention makes full use of the performance of the device itself and common physical principles to realize the functional requirements of the machine, simplifies the structure and control, thereby improving the system stability and greatly reducing the cost.

Description

Translated fromChinese

一种全自动生化分析仪液路系统A fully automatic biochemical analyzer liquid circuit system

技术领域technical field

本发明涉及医学仪器技术领域，尤其涉及一种全自动生化分析仪液路系统。The invention relates to the technical field of medical instruments, in particular to a liquid circuit system of an automatic biochemical analyzer.

背景技术Background technique

全自动生化分析仪是临床检验中最常使用的重要分析仪器之一，在辅助诊断、疗效检测、健康检查、药物滥用等方面具有重要意义，其测量速度快、准确性高、消耗试剂量小，操作简便，采用光电比色原理，把分析过程中的取样、加试剂、混匀、保温反应、检测、结果计算和显示以及清洗等步骤进行自动化操作，测量体液中某种特定化学成分，是各级医疗、疾病控制单位、生物学研究必不可少的仪器，也是当前医疗器械产业发展最快的领域之一。Fully automatic biochemical analyzer is one of the most commonly used important analytical instruments in clinical testing. It is of great significance in auxiliary diagnosis, curative effect testing, health inspection, drug abuse, etc. It has fast measurement speed, high accuracy and small consumption of reagents. It is easy to operate. It adopts the principle of photoelectric colorimetry to automate the steps of sampling, reagent addition, mixing, thermal reaction, detection, result calculation and display, and cleaning in the analysis process to measure a specific chemical composition in body fluids. It is an indispensable instrument for medical treatment, disease control units, and biological research at all levels, and it is also one of the fastest growing fields of the current medical device industry.

目前，各个企业均按照相同的工作原理，设计出各种形式的液路系统，生化分析仪的液路系统主要实现以下功能：样本的加注和清洗、试剂的加注和清洗、搅拌棒的清洗、反应杯的清洗、清洗液的加注、针的废液处理、冷凝水的废液处理、反应杯的废液处理、整机液路系统排空处理、腐蚀性管路的维护处理。At present, various companies have designed various forms of liquid circuit systems according to the same working principle. The liquid circuit system of the biochemical analyzer mainly realizes the following functions: filling and cleaning of samples, filling and cleaning of reagents, and cleaning of stirring rods. Cleaning, cleaning of reaction cups, filling of cleaning liquid, waste liquid treatment of needles, waste liquid treatment of condensate water, waste liquid treatment of reaction cups, emptying treatment of liquid circuit system of the whole machine, maintenance treatment of corrosive pipelines.

现有生化分析仪的液路系统在成本、功能、维护三个方面平衡性把握较差，现有技术中，不同测试速度的液路模块无法兼容，器件种类繁多，性能不稳定，增大了成本和售后维护难度；使用昂贵的真空泵和脱气膜脱离溶解在水中的空气；使用大流量磁励离心泵和齿轮泵清洗针内、外壁，磁励离心泵和齿轮泵需要不间断工作，对寿命和成本要求较高；使用微型磁励泵和定量泵进行整机清洗液循环和加注，无灌冲回路，仪器长期不使用会加速管路老化和结晶堵塞；清洗手抽废液结构复杂或简单，造成成本过高或废液抽离不彻底；反应杯加注结构复杂或简单，造成成本过高或清洗手滴液；使用隔膜泵进行整机废液的抽排，泵负载大，膜片极易损耗或被反应物粘结。The liquid circuit system of the existing biochemical analyzer is poorly balanced in terms of cost, function and maintenance. In the prior art, the liquid circuit modules of different test speeds are incompatible, and there are many types of devices and unstable performance. Cost and after-sales maintenance difficulty; use expensive vacuum pump and degassing membrane to get rid of the air dissolved in water; use high-flow magnetic centrifugal pump and gear pump to clean the inner and outer walls of the needle, magnetic centrifugal pump and gear pump need to work continuously, The life and cost requirements are relatively high; the micro-magnetic pump and quantitative pump are used for the circulation and filling of the cleaning liquid of the whole machine, and there is no filling and flushing circuit. If the instrument is not used for a long time, it will accelerate the aging of the pipeline and crystal blockage; Or simple, resulting in high cost or incomplete extraction of waste liquid; complex or simple filling structure of the reaction cup, resulting in high cost or cleaning hand dripping; using diaphragm pump to pump and discharge waste liquid of the whole machine, the pump load is large, Membranes are highly susceptible to wear or to be bonded by reactants.

发明内容SUMMARY OF THE INVENTION

有鉴于此，本发明的目的是提供一种结构简单可靠、水压稳定、响应速度快、功能完善、成本低廉、可维护性强、兼容不同测试速度的全自动生化分析仪液路系统。In view of this, the purpose of the present invention is to provide a fully automatic biochemical analyzer liquid circuit system with simple and reliable structure, stable water pressure, fast response speed, perfect function, low cost, strong maintainability, and compatibility with different test speeds.

本发明通过以下技术手段解决上述技术问题：The present invention solves the above-mentioned technical problems through the following technical means:

一种全自动生化分析仪液路系统，包括：A fully automatic biochemical analyzer liquid circuit system, comprising:

加水模块，用于维持所述液路系统水压；a water adding module for maintaining the water pressure of the hydraulic system;

加样清洗模块，用于对样本、试剂进行吸取和加注以及对样本针、试剂针进行清洗；The sample addition and cleaning module is used to aspirate and refill samples and reagents, and to clean sample needles and reagent needles;

反应杯清洗模块，用于对反应杯进行清洗；The reaction cup cleaning module is used to clean the reaction cup;

以及，废液收集模块，用于对废液进行收集；And, the waste liquid collection module is used to collect the waste liquid;

所述加水模块包括储水单元和与储水单元连接的加压单元，所述加样清洗模块包括加样针清洗单元、试剂针清洗单元和搅拌棒清洗单元，所述反应杯清洗模块包括反应杯清洗液路单元和双头负压泵，所述反应杯清洗液路单元和双头负压泵均与反应杯内部相连通，所述废液收集模块包括废液收集单元和与废液收集单元相连通的试剂冷藏室冷凝管路，所述加样针清洗单元、试剂针清洗单元和搅拌棒清洗单元的出水端均与试剂冷藏室冷凝管路相连通，所述双头负压泵的出水端与废液收集单元相连通，所述加样针清洗单元、试剂针清洗单元、搅拌棒清洗单元和反应杯清洗液路单元均并联在所述加压单元的出水口上。The water adding module includes a water storage unit and a pressurizing unit connected to the water storage unit, the sample adding cleaning module includes a sample adding needle cleaning unit, a reagent needle cleaning unit and a stirring bar cleaning unit, and the reaction cup cleaning module includes a reaction A cup cleaning liquid circuit unit and a double-head negative pressure pump, both of the reaction cup cleaning liquid circuit unit and the double-headed negative pressure pump are in communication with the interior of the reaction cup, and the waste liquid collection module includes a waste liquid collection unit and a waste liquid collection unit. The condensing pipeline of the reagent refrigerating room connected to the unit, the water outlet ends of the sample needle cleaning unit, the reagent needle cleaning unit and the stirring rod cleaning unit are all connected with the condensation pipeline of the reagent refrigerating room, and the double-head negative pressure pump The water outlet is communicated with the waste liquid collection unit, and the sample needle cleaning unit, the reagent needle cleaning unit, the stirring bar cleaning unit and the reaction cup cleaning liquid circuit unit are all connected in parallel to the water outlet of the pressurizing unit.

进一步，所述储水单元包括外部进水桶和安装在外部进水桶内的第一液位传感器，所述加压单元包括依次连接的进水阀、齿轮泵、压力检测装置、囊式压力罐和加热罐，所述进水阀与所述外部进水桶相连通，所述加热罐上设置有所述出水口。Further, the water storage unit includes an external water inlet bucket and a first liquid level sensor installed in the external water inlet bucket, and the pressurizing unit includes a water inlet valve, a gear pump, a pressure detection device, a bladder-type pressure tank and A heating tank, the water inlet valve communicates with the external water inlet bucket, and the water outlet is provided on the heating tank.

进一步，所述进水阀与所述外部进水桶之间还安装有过滤器。Further, a filter is also installed between the water inlet valve and the external water inlet bucket.

.根据权利要求所述的一种全自动生化分析仪液路系统，其特征在于：所述加样针清洗单元包括依次连接的加样针内壁冲洗管路和加样针外壁冲洗管路，所述试剂针清洗单元包括多条一一对应的试剂针内壁冲洗管路和试剂针外壁冲洗管路，所述搅拌棒清洗单元包括多条搅拌棒冲洗管路，所述加压单元的出水口上安装有三通管，所述加样针内壁冲洗管路的进水端、试剂针内壁冲洗管路的进水端均与三通管的一端相连通，所述三通管的剩余一端上安装有调压阀，所述加样针外壁冲洗管路、试剂针外壁冲洗管路和搅拌棒冲洗管路均与调压阀的出水端连通。. A fully automatic biochemical analyzer liquid circuit system according to claim, characterized in that: the sample-adding needle cleaning unit comprises a sample-adding needle inner wall flushing pipeline and a sample-adding needle outer wall flushing pipeline, which are sequentially connected. The reagent needle cleaning unit includes a plurality of one-to-one corresponding reagent needle inner wall flushing pipelines and reagent needle outer wall flushing pipelines, the stirring rod cleaning unit includes a plurality of stirring rod flushing pipelines, and the water outlet of the pressurizing unit is on the A tee pipe is installed, the water inlet end of the inner wall flushing pipeline of the sample needle and the water inlet end of the reagent needle inner wall flushing pipeline are all connected with one end of the tee pipe, and the remaining end of the tee pipe is installed with a tee pipe. The pressure regulating valve, the outer wall flushing pipeline of the sample injection needle, the outer wall flushing pipeline of the reagent needle and the stirring rod flushing pipeline are all connected with the water outlet end of the pressure regulating valve.

进一步，所述加样针内壁冲洗管路包括依次相连通的加样针内壁冲洗电磁阀、内壁精密压力传感器、加样柱塞泵和加样针，所述加样针外壁冲洗管路包括加样针外壁清洗电磁阀和与加样针外壁清洗电磁阀相连通的加样针清洗喷头，所述加样针外壁清洗电磁阀的进水端和所述调压阀的出水端相连通，所述加样针清洗喷头的底部设置有管道与所述试剂冷藏室冷凝管路相连通。Further, the sample-adding needle inner wall flushing pipeline includes a sample-adding needle inner-wall flushing solenoid valve, an inner wall precision pressure sensor, a sample-adding plunger pump and a sample-adding needle that are sequentially connected, and the sample-adding needle outer wall flushing pipeline includes a sample-adding needle flushing pipeline. The sample needle outer wall cleaning solenoid valve and the sample needle cleaning nozzle communicated with the sample needle outer wall cleaning solenoid valve, the water inlet end of the sample needle outer wall cleaning solenoid valve is communicated with the water outlet end of the pressure regulating valve, so The bottom of the sample needle cleaning nozzle is provided with a pipeline that communicates with the condensation pipeline of the reagent refrigerating chamber.

进一步，所述试剂针内壁冲洗管路包括依次相连通的试剂针冲洗电磁阀、试剂柱塞泵和试剂针，所述试剂针外壁冲洗管路包括试剂针外壁清洗电磁阀和与试剂针外壁清洗电磁阀相连通的试剂针清洗喷头，所述试剂针清洗喷头的底部设置有管道与所述试剂冷藏室冷凝管路相连通。Further, the reagent needle inner wall flushing pipeline includes a reagent needle flushing solenoid valve, a reagent plunger pump and a reagent needle that are connected in sequence, and the reagent needle outer wall flushing pipeline includes a reagent needle outer wall cleaning solenoid valve and a reagent needle outer wall cleaning solenoid valve. The reagent needle cleaning spray head communicated with the solenoid valve is provided with a pipeline at the bottom of the reagent needle cleaning spray head, which is communicated with the condensation pipeline of the reagent refrigerator compartment.

进一步，所述搅拌棒冲洗管路包括搅拌棒清洗电磁阀和与搅拌棒清洗电磁阀相连接的清洗槽，所述搅拌棒清洗电磁阀的进水端与所述调压阀的出水端相连通，所述清洗槽的底部设置有管道与所述试剂冷藏室冷凝管路相连通。Further, the stirring rod washing pipeline includes a stirring rod cleaning solenoid valve and a cleaning tank connected with the stirring rod cleaning solenoid valve, and the water inlet end of the stirring rod cleaning solenoid valve is communicated with the water outlet end of the pressure regulating valve. The bottom of the cleaning tank is provided with a pipeline that communicates with the condensation pipeline of the reagent refrigerator compartment.

进一步，所述反应杯清洗液路单元包括回流液路和清洗液路，所述回流液路包括三通回流电磁阀、三根清水注水管及出水管，所述清水注水管和出水管安装在三通回流电磁阀的两端口上，所述三通回流电磁阀的进水端与所述调压阀的出水端相连通，所述清水注水管的出水端位于所述反应杯内部，所述出水管与试剂冷藏室冷凝管路相连通，所述清洗液路包括依次连接的清洗液储存桶、清洗液三通电磁阀、清洗液泵和清洗液阀，所述清洗液阀的出水口上安装有清洗液管，所述清洗液管的末端位于所述反应杯内部，所述清洗液三通电磁阀的剩余一端与所述调压阀的出水端相连通。Further, the cuvette cleaning liquid circuit unit includes a return liquid circuit and a cleaning liquid circuit, and the reflux liquid circuit includes a three-way return solenoid valve, three clean water injection pipes and water outlet pipes, and the clean water injection pipes and water outlet pipes are installed in the three. On the two ports of the return solenoid valve, the water inlet end of the three-way return solenoid valve is communicated with the water outlet end of the pressure regulating valve, the water outlet end of the clean water injection pipe is located inside the reaction cup, and the outlet end is located inside the reaction cup. The water pipe is communicated with the condensation pipeline of the reagent refrigerating chamber, and the cleaning liquid circuit includes a cleaning liquid storage bucket, a cleaning liquid three-way solenoid valve, a cleaning liquid pump and a cleaning liquid valve, which are connected in sequence, and the water outlet of the cleaning liquid valve is installed on the There is a cleaning liquid pipe, the end of the cleaning liquid pipe is located inside the reaction cup, and the remaining end of the cleaning liquid three-way solenoid valve is communicated with the water outlet end of the pressure regulating valve.

进一步，所述废液收集单元包括废液收集桶和安装在废液收集桶内的第二液位传感器。Further, the waste liquid collection unit includes a waste liquid collection barrel and a second liquid level sensor installed in the waste liquid collection barrel.

进一步，所述废液收集桶上设置有通气孔。Further, a ventilation hole is provided on the waste liquid collection barrel.

本发明的有益效果：Beneficial effects of the present invention:

本发明提供的全自动生化分析仪液路系统，各模块中的泵、囊式压力罐、电磁阀、调压阀、双头负压泵等均使用简单且性能稳定的成熟型器件，充分利用器件本身性能和常用物理原理来实现机器功能需求，简化结构和控制，从而提高系统稳定性和大幅度降低成本；利用囊式压力罐可存储和缓冲能量，使水压稳定且有极快的响应速度，并增大空气在水中溶解度，省去高成本的脱气装置；通过更改加水泵和过滤器规格，增删电磁阀和清洗槽数量，即可快速实现200速-800速兼容；利用三通电磁阀和连通器原理，解决清洗手滴水和清洗液结晶问题；利用双头负压泵提供较高瞬时负压的性能，省去复杂的负压储存装置和气液分离装置；利用仪器本身高度差和大口径废液管路，实现稀废液自流，省去废液泵。In the liquid circuit system of the fully automatic biochemical analyzer provided by the present invention, the pumps, bladder-type pressure tanks, solenoid valves, pressure regulating valves, double-head negative pressure pumps, etc. in each module are all mature devices with simple and stable performance. The performance of the device itself and common physical principles are used to realize the functional requirements of the machine, simplify the structure and control, thereby improving the stability of the system and greatly reducing the cost; the bladder-type pressure tank can store and buffer energy, so that the water pressure is stable and has an extremely fast response. speed, and increase the solubility of air in water, eliminating the need for high-cost degassing devices; by changing the specifications of the water pump and filter, adding or deleting the number of solenoid valves and cleaning tanks, you can quickly achieve 200-speed-800-speed compatibility; using three-way The principle of solenoid valve and communication device solves the problem of water dripping and cleaning liquid crystallization; the double-head negative pressure pump is used to provide high instantaneous negative pressure performance, eliminating the need for complex negative pressure storage devices and gas-liquid separation devices; using the height difference of the instrument itself And large-diameter waste liquid pipeline to realize the self-flow of dilute waste liquid, eliminating the need for waste liquid pump.

附图说明Description of drawings

图1为本发明一种全自动生化分析仪液路系统的结构示意图。FIG. 1 is a schematic structural diagram of a liquid circuit system of an automatic biochemical analyzer according to the present invention.

图2为本发明一种全自动生化分析仪液路系统中加水模块的结构示意图。FIG. 2 is a schematic structural diagram of a water adding module in a liquid circuit system of a fully automatic biochemical analyzer according to the present invention.

图3为本发明一种全自动生化分析仪液路系统中加样清洗模块的结构示意图。FIG. 3 is a schematic structural diagram of a sample adding and cleaning module in a liquid circuit system of an automatic biochemical analyzer according to the present invention.

图4为本发明一种全自动生化分析仪液路系统中反应杯清洗模块的结构示意图。4 is a schematic structural diagram of a cuvette cleaning module in a liquid circuit system of an automatic biochemical analyzer according to the present invention.

图5为本发明一种全自动生化分析仪液路系统中废液收集模块的结构示意图。5 is a schematic structural diagram of a waste liquid collection module in a liquid circuit system of an automatic biochemical analyzer according to the present invention.

具体实施方式Detailed ways

以下将结合附图和具体实施例对本发明进行详细说明：The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments:

如图1所示，本发明的一种全自动生化分析仪液路系统，包括：As shown in Figure 1, a liquid circuit system of a fully automatic biochemical analyzer of the present invention includes:

用于维持所述液路系统水压的加水模块100，用于对样本、试剂进行吸取和加注以及对样本针、试剂针进行清洗的加样清洗模块200，用于对反应杯进行清洗的反应杯清洗模块300，以及，用于对废液进行收集的废液收集模块400；Thewater adding module 100 for maintaining the water pressure of the liquid circuit system, the sample adding andcleaning module 200 for absorbing and adding samples and reagents and cleaning the sample needles and reagent needles, and the cleaning module for cleaning the reaction cup. acuvette cleaning module 300, and a wasteliquid collection module 400 for collecting waste liquid;

所述加水模块100包括储水单元和与储水单元连接的加压单元，所述加样清洗模块200包括加样针清洗单元、试剂针清洗单元和搅拌棒清洗单元，所述反应杯清洗模块300包括反应杯清洗液路单元和双头负压泵33，所述反应杯清洗液路单元和双头负压泵33均与反应杯内部相连通，所述废液收集模块400包括废液收集单元和与废液收集单元相连通的试剂冷藏室冷凝管路，所述加样针清洗单元、试剂针清洗单元和搅拌棒清洗单元的出水端均与试剂冷藏室冷凝管路相连通，所述双头负压泵33的出水端与废液收集单元相连通，所述加样针清洗单元、试剂针清洗单元、搅拌棒清洗单元和反应杯清洗液路单元均并联在所述加压单元的出水口上。Thewater adding module 100 includes a water storage unit and a pressurizing unit connected to the water storage unit. The sample addingcleaning module 200 includes a sample adding needle cleaning unit, a reagent needle cleaning unit and a stirring bar cleaning unit. The reactioncup cleaning module 300 includes a cuvette cleaning liquid circuit unit and a double-head negative pressure pump 33, both of which are communicated with the inside of the cuvette, and the wasteliquid collection module 400 includes a waste liquid collection unit and the condensing pipeline of the reagent refrigeration room communicated with the waste liquid collection unit, the water outlet ends of the sample addition needle cleaning unit, the reagent needle cleaning unit and the stirring bar cleaning unit are all connected with the condensation pipeline of the reagent refrigeration room, and the The water outlet end of the double-head negative pressure pump 33 is communicated with the waste liquid collection unit, and the sample addition needle cleaning unit, the reagent needle cleaning unit, the stirring bar cleaning unit and the reaction cup cleaning liquid circuit unit are all connected in parallel with the pressure unit. on the water outlet.

具体地，如图2所示，所述储水单元包括外部进水桶34和安装在外部进水桶34内的第一液位传感器35，所述加压单元包括依次连接的进水阀1、齿轮泵2、压力检测装置3、囊式压力罐4和加热罐5，所述进水阀1与所述外部进水桶34相连通，所述加热罐5上设置有所述出水口，所述进水阀1与所述外部进水桶34之间还安装有过滤器40。引进囊式压力罐4作为整个液路系统的储能元件，环保橡胶膜片将气体与水隔离，罐内气体吸收和缓冲齿轮泵2提供的机械能，将水挤压到各个出水口，使内部水压稳定地维持在设定范围内，齿轮泵2只需间歇动作，较大延长齿轮泵2寿命，对部件使用效率高，且内部保持较大水压，出水响应速度快，增大空气溶解度，防止水中气体溢出，省去昂贵的消泡膜和负压泵等脱气装置。Specifically, as shown in FIG. 2 , the water storage unit includes an externalwater inlet barrel 34 and a firstliquid level sensor 35 installed in the externalwater inlet barrel 34 , and the pressurizing unit includes awater inlet valve 1 , a gear and a gear connected in sequence. Thepump 2, the pressure detection device 3, the bladder-type pressure tank 4 and theheating tank 5, thewater inlet valve 1 is communicated with the externalwater inlet barrel 34, theheating tank 5 is provided with the water outlet, and the waterinlet A filter 40 is also installed between thewater valve 1 and the externalwater inlet bucket 34 . The bladder-type pressure tank 4 is introduced as the energy storage element of the entire liquid circuit system. The environmental protection rubber diaphragm isolates the gas from the water. The gas in the tank absorbs and buffers the mechanical energy provided by thegear pump 2, and squeezes the water to each water outlet. The water pressure is stably maintained within the set range, and thegear pump 2 only needs to operate intermittently, which greatly prolongs the life of thegear pump 2, has high use efficiency for components, and maintains a large water pressure inside. The water response speed is fast and the air solubility is increased. , to prevent the gas from overflowing in the water, eliminating the need for expensive degassing devices such as defoaming membranes and negative pressure pumps.

进一步，所述加样针清洗单元包括依次连接的加样针内壁冲洗管路和加样针外壁冲洗管路，所述试剂针清洗单元包括多条一一对应的试剂针内壁冲洗管路和试剂针外壁冲洗管路，所述搅拌棒清洗单元包括多条搅拌棒冲洗管路，所述加压单元的出水口上安装有三通管，所述加样针内壁冲洗管路的进水端、试剂针内壁冲洗管路的进水端均与三通管的一端相连通，所述三通管的剩余一端上安装有调压阀6，所述加样针外壁冲洗管路、试剂针外壁冲洗管路和搅拌棒冲洗管路均与调压阀6的出水端连通。Further, the sample addition needle cleaning unit includes a sample addition needle inner wall rinse pipeline and a sample addition needle outer wall rinse pipeline connected in sequence, and the reagent needle cleaning unit includes a plurality of reagent needle inner wall rinse pipelines and reagents in one-to-one correspondence. The needle outer wall flushing pipeline, the stirring rod cleaning unit includes a plurality of stirring rod flushing pipelines, a tee pipe is installed on the water outlet of the pressurizing unit, the water inlet end of the sample injection needle inner wall flushing pipeline, the reagent The water inlet end of the needle inner wall flushing pipeline is connected with one end of the three-way tube, and thepressure regulating valve 6 is installed on the remaining end of the three-way tube. Both the road and the stirring rod flushing pipeline are communicated with the outlet end of thepressure regulating valve 6 .

具体地，如图3所示，本实施例中所述加样针内壁冲洗管路包括依次相连通的加样针内壁冲洗电磁阀8、内壁精密压力传感器10、加样柱塞泵12和加样针15，所述加样针外壁冲洗管路包括加样针外壁清洗电磁阀25和与加样针外壁清洗电磁阀25相连通的加样针清洗喷头20，所述加样针外壁清洗电磁阀25的进水端和所述调压阀6的出水端相连通，所述加样针清洗喷头20的底部设置有管道与所述试剂冷藏室冷凝管路相连通。Specifically, as shown in FIG. 3 , the pipeline for flushing the inner wall of the sample injection needle in this embodiment includes asolenoid valve 8 for flushing the inner wall of the sample injection needle, an inner wallprecision pressure sensor 10 , a sample injection plunger pump 12 and a sample injection needle that are connected in sequence. Thesample needle 15, the sample addition needle outer wall flushing pipeline includes the sample addition needle outer wall cleaningsolenoid valve 25 and the sample additionneedle cleaning nozzle 20 communicated with the sample addition needle outer wall cleaningsolenoid valve 25. The sample addition needle outer wall cleaningsolenoid valve 20 The water inlet end of thevalve 25 is communicated with the water outlet end of thepressure regulating valve 6, and the bottom of the sampleneedle cleaning nozzle 20 is provided with a pipeline that communicates with the condensation pipeline of the reagent refrigerator compartment.

具体地，当样本针15旋转至样本盘吸样位上方，加样柱塞泵12吸取定量空气后，由液面感应板精确控制样本针15下行，接触到液面后继续下行X3mm，加样柱塞泵12吸取X4μL样本和一定富余样本量后，柱塞泵12反向打出部分样本消除柱塞泵反转间隙，接着样本针15从样本盘抬起，旋转至指定反应杯，控制加样柱塞泵12打出X4μL样本，本发明通过所述加样柱塞泵12和样本针15的协作完成样本的拾取和加注。Specifically, when thesample needle 15 is rotated to the top of the suction position of the sample plate, after the sample adding plunger pump 12 sucks a certain amount of air, thesample needle 15 is precisely controlled by the liquid level sensing plate to descend, and after touching the liquid level, thesample needle 15 continues to descend for X3mm, and the sample is added. After the plunger pump 12 sucks the X4 μL sample and a certain amount of excess sample, the plunger pump 12 reverses a part of the sample to eliminate the plunger pump reversal gap, and then thesample needle 15 is lifted from the sample plate and rotated to the designated cuvette to control the sample addition. The plunger pump 12 dispenses X4 μL of sample, and the present invention completes the picking and filling of the sample through the cooperation of the sample adding plunger pump 12 and thesample needle 15 .

具体的，当样本针15旋转至加样针清洗喷头20位置时，同时通电打开加样针内壁冲洗电磁阀8和加样针外壁清洗电磁阀25进行清洗，加样柱塞泵12将剩余富余样本量打出，先断电关闭加样针内壁冲洗电磁阀8再断电关闭加样针外壁清洗电磁阀25，利用外部水流冲刷针头，防止加样针15针尖挂液，内壁冲洗电磁阀8开启的过程中，内壁精密压力传感器10检测清洗水压波动曲线，判断是否存在堵针现象，从而完成加样针15的清洗。Specifically, when thesample needle 15 rotates to the position of the sampleneedle cleaning nozzle 20, the power is turned on at the same time to open the sample needle inner wall flushingsolenoid valve 8 and the sample needle outer wall cleaningsolenoid valve 25 for cleaning. When the sample volume is dispensed, first turn off the power to close the inner wall flushingsolenoid valve 8 of the sampling needle, then turn off the power to close the outer wall cleaningsolenoid valve 25 of the sampling needle, and use the external water flow to flush the needle to prevent the needle tip of thesampling needle 15 from hanging liquid, and the inner wall flushingsolenoid valve 8 is turned on. During the process, the inner wallprecision pressure sensor 10 detects the cleaning water pressure fluctuation curve to determine whether there is a needle blocking phenomenon, so as to complete the cleaning of thesample needle 15 .

具体地，如图3所示，本实施例中所述试剂针内壁冲洗管路包括试剂一针内壁冲洗管路和试剂二针内壁冲洗管路，所述试剂一针冲洗管路包括依次相连通的试剂一针冲洗电磁阀7、试剂一针柱塞泵13和试剂一针14，所述试剂二针内壁冲洗管路包括依次连接的试剂二针冲洗电磁阀9、试剂二针柱塞泵11和试剂二针16，与所述试剂针内壁冲洗管路相对应的，所述试剂针外壁冲洗管路包括试剂一针外壁冲洗管路和试剂二针外壁冲洗管路，所述试剂一针外壁冲洗管路包括试剂一针外壁清洗电磁阀24和与试剂一针外壁清洗电磁阀24相连通的试剂一针清洗喷头19，所述试剂二针外壁冲洗管路包括试剂二针外壁清洗电磁阀26和与试剂二针外壁清洗电磁阀26相连通的试剂二针清洗喷头21，所述试剂针清洗喷头19的底部、所述试剂二针清洗喷头21的底部设置有管道与所述试剂冷藏室冷凝管路相连通。Specifically, as shown in FIG. 3 , in this embodiment, the reagent needle inner wall flushing pipeline includes a reagent one-needle inner wall flushing pipeline and a reagent two-needle inner wall flushing pipeline, and the reagent one-needle flushing pipeline includes sequentially connected The reagent one-needleflushing solenoid valve 7, the reagent-one-needle plunger pump 13 and the reagent-one-needle 14, the reagent two-needle inner wall flushing pipeline includes the reagent two-needleflushing solenoid valve 9 and the reagent two-needle plunger pump 11 connected in sequence. Thesecond reagent needle 16 corresponds to the inner wall flushing pipeline of the reagent needle. The reagent needle outer wall flushing pipeline includes thereagent 1 needle outer wall flushing pipeline and the reagent second needle outer wall flushing pipeline. Thereagent 1 needle outer wall flushing pipeline The flushing pipeline includes a reagent one-needle outer wall cleaningsolenoid valve 24 and a reagent one-needle cleaning nozzle 19 that communicates with the reagent one-needle outer wall cleaningsolenoid valve 24. The reagent two-needle outer wall flushing pipeline includes a reagent two-needle outer wall cleaningsolenoid valve 26. The reagent two-needle cleaning nozzle 21 communicates with the reagent two-needle outer wall cleaningsolenoid valve 26. The bottom of the reagent two-needle cleaning nozzle 19 and the bottom of the reagent two-needle cleaning nozzle 21 are provided with pipes to condense with the reagent refrigerator. The pipes are connected.

具体地，当试剂一针14旋转至试剂一盘吸样位上方，试剂一针柱塞泵13吸取定量空气后，由液面感应板精确控制加样针下行，接触到液面后继续下行X5mm，试剂一针柱塞泵13吸取X6μL试剂和一定富余试剂量后，试剂一针柱塞泵13反向打出部分试剂消除试剂一针柱塞泵13反转间隙，接着试剂一针14从试剂一盘抬起，旋转至指定反应杯，试剂一针柱塞泵13打出X6μL样本，本实施例中通过所述试剂一针柱塞泵13和试剂一针14的协作完成试剂一的拾取和加注。Specifically, when thereagent 1needle 14 is rotated to the top of the sample suction position of thereagent 1 plate, after thereagent 1needle plunger pump 13 sucks a certain amount of air, the liquid level sensing plate accurately controls the sample needle to descend, and continues to descend X5mm after touching the liquid level. , after the reagent one-needle plunger pump 13 sucks X6 μL of reagent and a certain amount of surplus reagent, the reagent-one-needle plunger pump 13 reversely pushes out part of the reagent to eliminate the reversal gap of the reagent-one-needle plunger pump 13, and then the reagent one-needle 14 flows from the reagent-one The plate is lifted up, rotated to the designated reaction cup, and the reagent 1-needle plunger pump 13 dispenses X6 μL samples. In this embodiment, thereagent 1 is picked up and filled by the cooperation of the reagent 1-needle plunger pump 13 and thereagent 1needle 14. .

进一步，当试剂一针14旋转至试剂一针清洗喷头19位置时，同时通电打开试剂一针内壁冲洗电磁阀7和试剂一针外壁清洗电磁阀24进行清洗，试剂一针柱塞泵13将试剂一剩余富余试剂量打出，先断电关闭试剂一针内壁冲洗电磁阀7再断电关闭试剂一针外壁清洗电磁阀24，利用外部水流冲刷针头，防止试剂一针14针尖挂液，从而完成试剂一针14的清洗，因试剂针口径大，且试剂纯净度较高，不存在堵针现象，无需检测堵针，试剂二针46动作过程与试剂一针14一致。Further, when thereagent 1needle 14 is rotated to the position of thereagent 1needle cleaning nozzle 19, the power is turned on at the same time to open thereagent 1 needle inner wall flushingsolenoid valve 7 and thereagent 1 needle outer wall cleaningsolenoid valve 24 for cleaning, and thereagent 1needle plunger pump 13 flushes the reagent. Once the remaining surplus reagent is dispensed, first power off and close the inner wall flushingsolenoid valve 7 ofreagent 1, and then turn off the power and close the outer wall cleaningsolenoid valve 24 ofreagent 1, and use external water flow to flush the needle to prevent liquid from the tip ofreagent 14, so as to complete the reagent In the cleaning of thefirst needle 14, due to the large diameter of the reagent needle and the high purity of the reagent, there is no needle blocking phenomenon, and there is no need to detect the blocked needle. The action process of the second reagent needle 46 is consistent with that of thefirst reagent needle 14.

本实施例中，试剂针内壁冲洗管路和样本针内壁冲洗管路是液路系统中重要的维护管路之一，内壁清洗压力大，且内壁管路口径小，无法使用卡箍紧固，所以使用密封性能较佳的端面密封，即使用热熔翻边管路，配合拥有较高精密平面度的挤压接头，较大幅度的降低泄漏概率。调压阀6为膜片式调压阀，内部膜片根据前后压差自动调节阀张合宽度，使试剂一针清洗喷头19、加样针清洗喷头20、试剂二针清洗喷头21出水压力保持恒定，杜绝清洗水量时大时小的现象出现。In this embodiment, the inner wall flushing pipeline of the reagent needle and the inner wall flushing pipeline of the sample needle are one of the important maintenance pipelines in the liquid circuit system. The inner wall cleaning pressure is large, and the diameter of the inner wall pipeline is small, so the clamps cannot be used to fasten them. Therefore, the use of end-face seals with better sealing performance, that is, the use of hot-melt flanging pipes, combined with extruded joints with high precision flatness, can greatly reduce the probability of leakage. Thepressure regulating valve 6 is a diaphragm type pressure regulating valve. The inner diaphragm automatically adjusts the opening and closing width of the valve according to the front and rear pressure difference, so that the water outlet pressure of the reagent one-needle cleaning nozzle 19, the sample addingneedle cleaning nozzle 20, and the reagent two-needle cleaning nozzle 21 can be maintained. Constant, to prevent the phenomenon that the amount of cleaning water is large and small.

具体地，如图3所示，本实施例中，所述搅拌棒冲洗管路包括试剂搅拌棒冲洗管路和样本搅拌棒冲洗管路，所述试剂搅拌棒冲洗管路包括试剂搅拌棒清洗电磁阀28和与试剂搅拌棒清洗电磁阀28相连接的第一清洗槽23，所述样本搅拌棒冲洗管路包括样本搅拌棒清洗电磁阀27和与样本搅拌棒清洗电磁阀27相连通的第二清洗槽22，所述试剂搅拌棒清洗电磁阀28和样本搅拌棒清洗电磁阀27的进水端均与所述调压阀6的出水端相连通，所述第一清洗槽23和第二清洗槽22的底部均设置有管道与所述试剂冷藏室冷凝管路相连通。Specifically, as shown in FIG. 3 , in this embodiment, the stirring rod flushing pipeline includes a reagent stirring rod flushing pipeline and a sample stirring rod flushing pipeline, and the reagent stirring rod flushing pipeline includes a reagent stirring rod cleaning electromagnetic Thevalve 28 and thefirst cleaning tank 23 connected with the reagent stirring rod cleaningsolenoid valve 28, the sample stirring rod flushing pipeline includes the sample stirring rod cleaningsolenoid valve 27 and the second stirring rod cleaningsolenoid valve 27. Thecleaning tank 22, the water inlet end of the reagent stirring rod cleaningsolenoid valve 28 and the sample stirring rod cleaningsolenoid valve 27 are all connected with the water outlet end of thepressure regulating valve 6, and thefirst cleaning tank 23 and the second cleaning tank The bottoms of thetanks 22 are all provided with pipes to communicate with the condensation pipes of the reagent refrigerator compartment.

进一步，如图4所示，所述反应杯清洗液路单元包括回流液路和清洗液路，所述回流液路包括三通回流电磁阀29、三根清水注水管及出水管，所述清水注水管和出水管分别安装在三通回流电磁阀29的两端口上，所述三通回流电磁阀29的进水端与所述调压阀6的出水端相连通，所述清水注水管的出水端位于所述反应杯内部，所述出水管与试剂冷藏室冷凝管路相连通，所述清洗液路包括依次连接的清洗液储存桶36、清洗液三通电磁阀30、清洗液泵31和清洗液阀32，所述清洗液阀32的出水口上安装有清洗液管，所述清洗液管的末端位于所述反应杯内部，所述清洗液三通电磁阀30的剩余一端与所述调压阀6的出水端相连通，所述清洗液储存桶36内安装有第二液位传感器37。Further, as shown in FIG. 4 , the cuvette cleaning liquid circuit unit includes a return liquid circuit and a cleaning liquid circuit, and the return liquid circuit includes a three-wayreturn solenoid valve 29, three clean water injection pipes and a water outlet pipe. The water pipe and the water outlet pipe are respectively installed on the two ports of the three-wayreturn solenoid valve 29, the water inlet end of the three-wayreturn solenoid valve 29 is connected with the water outlet end of thepressure regulating valve 6, and the water outlet of the clean water injection pipe is connected. The end is located inside the reaction cup, the water outlet pipe is communicated with the condensation pipeline of the reagent refrigeration room, and the cleaning liquid circuit includes a cleaningliquid storage bucket 36, a cleaning liquid three-way solenoid valve 30, a cleaningliquid pump 31 and The cleaningliquid valve 32, a cleaning liquid pipe is installed on the water outlet of the cleaningliquid valve 32, the end of the cleaning liquid pipe is located inside the reaction cup, and the remaining end of the cleaning liquid three-way solenoid valve 30 is connected to the The water outlet ends of thepressure regulating valve 6 are communicated with each other, and a secondliquid level sensor 37 is installed in the cleaningliquid storage bucket 36 .

具体地，测试开始前，会清洗一定数量的反应杯，清洗手驱动电机旋转，将清洗手41下降到反应杯口，此时，双头负压泵33开始动作，清洗手41下降到反应杯底吸完废液后，驱动电机反转，使清洗手41上抬一定距离，此时清洗液泵31、清洗液阀32、三通回流电磁阀29通电X7秒，清洗手驱动电机反转，使清洗手41抬到最上端，关闭双头负压泵33完成注水，重复多次流程，直至全部反应杯清洗完毕。Specifically, before the test starts, a certain number of reaction cups are cleaned, the cleaning hand drives the motor to rotate, and the cleaninghand 41 is lowered to the mouth of the reaction cup. At this time, the double-head negative pressure pump 33 starts to operate, and the cleaninghand 41 descends to the reaction cup. After the waste liquid is sucked at the bottom, the driving motor is reversed, so that the cleaninghand 41 is lifted up a certain distance. At this time, the cleaningliquid pump 31, the cleaningliquid valve 32, and the three-wayreturn solenoid valve 29 are powered on for X7 seconds, and the cleaning hand driving motor is reversed. Lift the cleaninghand 41 to the uppermost end, close the double-head negative pressure pump 33 to complete the water injection, and repeat the process several times until all the reaction cups are cleaned.

本实施例中，在抽废液和加注纯水和清洗液过程中均使用独立的金属管，且抽废液金属管略长于加注金属管，此结构可完成废液抽净、清洗液和纯水的加注又可完成针尖的清洗，防止对下一个样本清洗时产生交叉污染。并且，本实施例通过改30良双头负压泵33单向膜片硬度，从而增大双头负压泵33动作的瞬时负压，保证在无储压罐、负压传感器储压的情况下，依旧拥有足够大的负压强度，保证反应杯清洗效果。In this embodiment, independent metal pipes are used in the process of pumping waste liquid and filling pure water and cleaning liquid, and the metal pipe for pumping waste liquid is slightly longer than the filling metal pipe. This structure can complete the extraction of waste liquid and cleaning liquid. Filling with pure water can complete the cleaning of the needle tip, preventing cross-contamination when cleaning the next sample. In addition, in this embodiment, by changing the hardness of the one-way diaphragm of the 30-meter double-head negative pressure pump 33, the instantaneous negative pressure of the double-head negative pressure pump 33 is increased to ensure that there is no pressure storage tank or negative pressure sensor. It still has a large enough negative pressure strength to ensure the cleaning effect of the cuvette.

注水过程中双头负压泵33持续工作，用来吸平反应杯液面，平衡注水的响应误差，使反应杯注水液面保持在同一个水平面，保障杯空白正常读取，防止反应杯溢水。During the water injection process, the double-head negative pressure pump 33 works continuously to level the liquid level of the reaction cup, balance the response error of water injection, keep the water injection liquid level of the reaction cup at the same level, ensure the normal reading of the cup blank, and prevent the reaction cup from overflowing. .

并且，清洗液泵31为微型隔膜泵，微型隔膜泵的成本低且性能稳定，加注量可调，且清洗液泵31前端管路增加清洗液三通电磁阀30，用于清洗液与纯水的切换，清洗完成后打开清洗液三通电磁阀30，多清洗一组反应杯，用纯水冲洗清洗液泵31和管路内剩余清洗液，防止仪器久置后出现清洗液结晶堵塞泵阀的现象，纯水带有一定压力，假使微型隔膜泵的膜片粘合，可冲开膜片单向阀，恢复微型隔膜泵状态。In addition, the cleaningliquid pump 31 is a micro-diaphragm pump. The micro-diaphragm pump has low cost and stable performance, and the filling amount is adjustable, and the front-end pipeline of the cleaningliquid pump 31 is equipped with a cleaning liquid three-way solenoid valve 30, which is used for cleaning liquid and pure water. For water switching, open the cleaning liquid three-way solenoid valve 30 after cleaning, clean one more set of reaction cups, and rinse the cleaningliquid pump 31 and the remaining cleaning liquid in the pipeline with pure water to prevent the cleaning liquid crystals from clogging the pump after the instrument is left for a long time. The phenomenon of the valve, pure water has a certain pressure, if the diaphragm of the micro-diaphragm pump is bonded, the diaphragm check valve can be opened to restore the micro-diaphragm pump state.

进一步，如图5所示，所述废液收集单元包括废液收集桶38和安装在废液收集桶38内的第二液位传感器39。Further, as shown in FIG. 5 , the waste liquid collection unit includes a wasteliquid collection tank 38 and a secondliquid level sensor 39 installed in the wasteliquid collection tank 38 .

具体的，试剂冷藏室冷凝管路选用耐酸碱腐蚀的大口径管路，配合大口径Y型三通接头与加样针清洗喷头20、试剂针清洗喷头和清洗槽底部相连通，结构上设计管路走向平滑，利用高度差实现加样针清洗喷头20、试剂针清洗喷头和清洗槽内的废水重力自流，所述废液收集桶38上设置有通气孔，减小废水下流阻力，无需依靠价格昂贵且需要经常维护的废液泵进行废液排空。Specifically, the condensing pipeline of the reagent refrigerator room is a large-diameter pipeline that is resistant to acid and alkali corrosion, and is connected with the sampleneedle cleaning nozzle 20, the reagent needle cleaning nozzle and the bottom of the cleaning tank with the large-diameter Y-type tee joint. The pipeline runs smoothly, and the height difference is used to realize the gravity self-flow of the waste water in the sampleneedle cleaning nozzle 20, the reagent needle cleaning nozzle and the cleaning tank. Expensive and frequently-maintained waste pumps for waste evacuation.

仪器开启后，系统通过第一液位传感器35判断外部进水桶34内储存有水，齿轮泵2和加水阀1开启，压力检测装置3持续检测囊式压力罐4内压力信号，待囊式压力罐4内部水压升高到设定范围的最大值X1，则关闭齿轮泵2和加水阀1，依次打开试剂一针外壁清洗电磁阀24、加样针外壁清洗电磁阀25、试剂二针外壁清洗电磁阀26、样本搅拌棒清洗电磁阀27、试剂搅拌棒清洗电磁阀28、试剂一针冲洗电磁阀7、加样针内壁冲洗电磁阀8、试剂二针冲洗电磁阀9，排空仪器内部气体，此时加热罐5开始加热，测试过程中压力检测装置3实时判断水压信号是否大于压力设定范围的最小值X2，从而控制齿轮泵2、加水阀1的启动，使囊式压力罐4即整机内部水压一直维持在设定范围X1-X2内，齿轮泵2流量远大于整机耗水流量，只需极短的时间即可将水压从X1MPa升高到X2MPa。After the instrument is turned on, the system judges that there is water stored in the externalwater inlet bucket 34 through the firstliquid level sensor 35, thegear pump 2 and thewater filling valve 1 are turned on, and the pressure detection device 3 continuously detects the pressure signal in the bladder pressure tank 4. When the water pressure inside the tank 4 rises to the maximum value X1 of the set range, close thegear pump 2 and thewater filling valve 1, and turn on the outer wall cleaningsolenoid valve 24 of the first reagent needle, the outer wall cleaningsolenoid valve 25 of the sample needle, and the outer wall of the second reagent needle.Cleaning solenoid valve 26, sample stirring rod cleaningsolenoid valve 27, reagent stirring rod cleaningsolenoid valve 28, reagent one-needleflushing solenoid valve 7, sample needle inner wall flushingsolenoid valve 8, reagent two-needleflushing solenoid valve 9, empty the inside of the instrument At this time, theheating tank 5 starts to heat. During the test, the pressure detection device 3 judges in real time whether the water pressure signal is greater than the minimum value X2 of the pressure setting range, so as to control the start of thegear pump 2 and thewater filling valve 1 to make the bladder pressure tank 4 That is, the internal water pressure of the whole machine has been maintained within the set range X1-X2, the flow rate ofgear pump 2 is much larger than the water consumption flow of the whole machine, and the water pressure can be increased from X1MPa to X2MPa in a very short time.

进一步，软件设定首次上水功能，通过压力检测装置3检测整机进水前内部压力是否为0，判断是否为首次进水，利用水压将管路内部空气排净，防止气体溶进水中，以及加热罐5干烧，影响清洗效果和加样精度，同时，第一液位传感器35检测到外部进水桶34内的水量较少时，系统会提示用户进行纯水补给，补给纯水时可能会有异物掉入，所以使用过滤器40进行过滤保护整机液路管道，防止异物堵塞液路管道。Further, the software sets the function of water supply for the first time. The pressure detection device 3 detects whether the internal pressure of the whole machine is 0 before the water enters, and judges whether it is the first water entry. The water pressure is used to drain the air inside the pipeline to prevent the gas from dissolving into the water. and theheating tank 5 is dry, which affects the cleaning effect and the accuracy of sample addition. At the same time, when the firstliquid level sensor 35 detects that the amount of water in the externalwater inlet bucket 34 is small, the system will prompt the user to replenish pure water. There may be foreign objects falling in, so use thefilter 40 to filter and protect the liquid pipeline of the whole machine to prevent foreign objects from blocking the liquid pipeline.

以上实施例仅用以说明本发明的技术方案而非限制，尽管参照较佳实施例对本发明进行了详细说明，本领域的普通技术人员应当理解，可以对本发明的技术方案进行修改或者等同替换，而不脱离本发明技术方案的宗旨和范围，其均应涵盖在本发明的权利要求范围当中。本发明未详细描述的技术、形状、构造部分均为公知技术。The above embodiments are only used to illustrate the technical solutions of the present invention and not to limit them. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced. Without departing from the spirit and scope of the technical solutions of the present invention, all of them should be included in the scope of the claims of the present invention. The technology, shape, and structural part that are not described in detail in the present invention are all well-known technologies.

Claims (10)

Translated fromChinese

1.一种全自动生化分析仪液路系统，其特征在于：包括：1. a fully automatic biochemical analyzer liquid circuit system, is characterized in that: comprise:加水模块，用于维持所述液路系统水压；a water adding module for maintaining the water pressure of the hydraulic system;加样清洗模块，用于对样本、试剂进行吸取和加注以及对样本针、试剂针进行清洗；The sample addition and cleaning module is used to aspirate and refill samples and reagents, and to clean sample needles and reagent needles;反应杯清洗模块，用于对反应杯进行清洗；The reaction cup cleaning module is used to clean the reaction cup;以及，废液收集模块，用于对废液进行收集；And, the waste liquid collection module is used to collect the waste liquid;所述加水模块包括储水单元和与储水单元连接的加压单元，所述加样清洗模块包括加样针清洗单元、试剂针清洗单元和搅拌棒清洗单元，所述反应杯清洗模块包括反应杯清洗液路单元和双头负压泵，所述反应杯清洗液路单元和双头负压泵均与反应杯内部相连通，所述废液收集模块包括废液收集单元和与废液收集单元相连通的试剂冷藏室冷凝管路，所述加样针清洗单元、试剂针清洗单元和搅拌棒清洗单元的出水端均与试剂冷藏室冷凝管路相连通，所述双头负压泵的出水端与废液收集单元相连通，所述加样针清洗单元、试剂针清洗单元、搅拌棒清洗单元和反应杯清洗液路单元均并联在所述加压单元的出水口上。The water adding module includes a water storage unit and a pressurizing unit connected to the water storage unit, the sample adding cleaning module includes a sample adding needle cleaning unit, a reagent needle cleaning unit and a stirring bar cleaning unit, and the reaction cup cleaning module includes a reaction A cup cleaning liquid circuit unit and a double-head negative pressure pump, both of the reaction cup cleaning liquid circuit unit and the double-headed negative pressure pump are in communication with the interior of the reaction cup, and the waste liquid collection module includes a waste liquid collection unit and a waste liquid collection unit. The condensing pipeline of the reagent refrigerating room connected to the unit, the water outlet ends of the sample needle cleaning unit, the reagent needle cleaning unit and the stirring rod cleaning unit are all connected with the condensation pipeline of the reagent refrigerating room, and the double-head negative pressure pump The water outlet is communicated with the waste liquid collection unit, and the sample needle cleaning unit, the reagent needle cleaning unit, the stirring bar cleaning unit and the reaction cup cleaning liquid circuit unit are all connected in parallel to the water outlet of the pressurizing unit.2.根据权利要求1所述的一种全自动生化分析仪液路系统，其特征在于，所述储水单元包括外部进水桶和安装在外部进水桶内的第一液位传感器，所述加压单元包括依次连接的进水阀、齿轮泵、压力检测装置、囊式压力罐和加热罐，所述进水阀与所述外部进水桶相连通，所述加热罐上设置有所述出水口。2 . The liquid circuit system of a fully automatic biochemical analyzer according to claim 1 , wherein the water storage unit comprises an external water inlet bucket and a first liquid level sensor installed in the external water inlet bucket. 3 . The pressure unit includes a water inlet valve, a gear pump, a pressure detection device, a bladder-type pressure tank and a heating tank connected in sequence, the water inlet valve communicates with the external water inlet barrel, and the heating tank is provided with the water outlet .3.根据权利要求2所述的一种全自动生化分析仪液路系统，其特征在于，所述进水阀与所述外部进水桶之间还安装有过滤器。3 . The liquid circuit system of an automatic biochemical analyzer according to claim 2 , wherein a filter is also installed between the water inlet valve and the external water inlet bucket. 4 .4.根据权利要求3所述的一种全自动生化分析仪液路系统，其特征在于：所述加样针清洗单元包括依次连接的加样针内壁冲洗管路和加样针外壁冲洗管路，所述试剂针清洗单元包括多条一一对应的试剂针内壁冲洗管路和试剂针外壁冲洗管路，所述搅拌棒清洗单元包括多条搅拌棒冲洗管路，所述加压单元的出水口上安装有三通管，所述加样针内壁冲洗管路的进水端、试剂针内壁冲洗管路的进水端均与三通管的一端相连通，所述三通管的剩余一端上安装有调压阀，所述加样针外壁冲洗管路、试剂针外壁冲洗管路和搅拌棒冲洗管路均与调压阀的出水端连通。4 . The liquid circuit system of an automatic biochemical analyzer according to claim 3 , wherein the sample-adding needle cleaning unit comprises a sample-adding needle inner wall flushing pipeline and a sample-adding needle outer wall flushing pipeline that are sequentially connected. 5 . The reagent needle cleaning unit includes a plurality of one-to-one corresponding reagent needle inner wall flushing pipelines and reagent needle outer wall flushing pipelines, the stirring rod cleaning unit includes a plurality of stirring rod flushing pipelines, and the outlet of the pressurizing unit A tee pipe is installed on the water outlet, and the water inlet end of the inner wall flushing pipeline of the sample injection needle and the water inlet end of the reagent needle inner wall flushing pipeline are all connected with one end of the tee pipe, and the remaining end of the tee pipe is connected to the A pressure regulating valve is installed, and the outer wall flushing pipeline of the sample injection needle, the outer wall flushing pipeline of the reagent needle and the stirring rod flushing pipeline are all connected with the water outlet end of the pressure regulating valve.5.根据权利要求4所述的一种全自动生化分析仪液路系统，其特征在于，所述加样针内壁冲洗管路包括依次相连通的加样针内壁冲洗电磁阀、内壁精密压力传感器、加样柱塞泵和加样针，所述加样针外壁冲洗管路包括加样针外壁清洗电磁阀和与加样针外壁清洗电磁阀相连通的加样针清洗喷头，所述加样针外壁清洗电磁阀的进水端和所述调压阀的出水端相连通，所述加样针清洗喷头的底部设置有管道与所述试剂冷藏室冷凝管路相连通。5 . The liquid circuit system of a fully automatic biochemical analyzer according to claim 4 , wherein the inner wall flushing pipeline of the sample injection needle comprises a sample injection needle inner wall flushing solenoid valve and an inner wall precision pressure sensor that are connected in sequence. 6 . , a sampling plunger pump and a sampling needle. The sampling needle outer wall flushing pipeline includes a sampling needle outer wall cleaning solenoid valve and a sampling needle cleaning nozzle connected to the sampling needle outer wall cleaning solenoid valve. The water inlet end of the needle outer wall cleaning solenoid valve is communicated with the water outlet end of the pressure regulating valve, and the bottom of the sample injection needle cleaning nozzle is provided with a pipeline that communicates with the condensation pipeline of the reagent refrigerator compartment.6.根据权利要求5所述的一种全自动生化分析仪液路系统，其特征在于，所述试剂针内壁冲洗管路包括依次相连通的试剂针冲洗电磁阀、试剂柱塞泵和试剂针，所述试剂针外壁冲洗管路包括试剂针外壁清洗电磁阀和与试剂针外壁清洗电磁阀相连通的试剂针清洗喷头，所述试剂针清洗喷头的底部设置有管道与所述试剂冷藏室冷凝管路相连通。6 . The liquid circuit system of an automatic biochemical analyzer according to claim 5 , wherein the inner wall flushing pipeline of the reagent needle comprises a reagent needle flushing solenoid valve, a reagent plunger pump and a reagent needle that are connected in sequence. 7 . The reagent needle outer wall flushing pipeline includes a reagent needle outer wall cleaning solenoid valve and a reagent needle cleaning nozzle that communicates with the reagent needle outer wall cleaning solenoid valve. The bottom of the reagent needle cleaning nozzle is provided with a pipeline to condense with the reagent refrigerator compartment The pipes are connected.7.根据权利要求6所述的一种全自动生化分析仪液路系统，其特征在于，所述搅拌棒冲洗管路包括搅拌棒清洗电磁阀和与搅拌棒清洗电磁阀相连接的清洗槽，所述搅拌棒清洗电磁阀的进水端与所述调压阀的出水端相连通，所述清洗槽的底部设置有管道与所述试剂冷藏室冷凝管路相连通。7. The liquid circuit system of a fully automatic biochemical analyzer according to claim 6, wherein the stirring rod flushing pipeline comprises a stirring rod cleaning solenoid valve and a cleaning tank connected with the stirring rod cleaning solenoid valve, The water inlet end of the stirring rod cleaning solenoid valve is communicated with the water outlet end of the pressure regulating valve, and the bottom of the cleaning tank is provided with a pipeline that communicates with the condensation pipeline of the reagent refrigerator compartment.8.根据权利要求7所述的一种全自动生化分析仪液路系统，其特征在于，所述反应杯清洗液路单元包括回流液路和清洗液路，所述回流液路包括三通回流电磁阀、三根清水注水管及出水管，所述清水注水管和出水管安装在三通回流电磁阀的两端口上，所述三通回流电磁阀的进水端与所述调压阀的出水端相连通，所述清水注水管的出水端位于所述反应杯内部，所述出水管与试剂冷藏室冷凝管路相连通，所述清洗液路包括依次连接的清洗液储存桶、清洗液三通电磁阀、清洗液泵和清洗液阀，所述清洗液阀的出水口上安装有清洗液管，所述清洗液管的末端位于所述反应杯内部，所述清洗液三通电磁阀的剩余一端与所述调压阀的出水端相连通。8 . The liquid circuit system of an automatic biochemical analyzer according to claim 7 , wherein the cuvette cleaning liquid circuit unit comprises a reflux liquid circuit and a cleaning liquid circuit, and the reflux liquid circuit comprises a three-way return flow. 9 . Solenoid valve, three clean water injection pipes and water outlet pipes, the clean water injection pipes and water outlet pipes are installed on the two ports of the three-way return solenoid valve, the water inlet end of the three-way return solenoid valve and the water outlet of the pressure regulating valve The water outlet end of the fresh water injection pipe is located inside the reaction cup, the water outlet pipe is connected with the condensation pipeline of the reagent refrigerator compartment, and the cleaning liquid circuit includes a cleaning liquid storage bucket, a cleaning liquid three A solenoid valve, a cleaning liquid pump and a cleaning liquid valve are connected. A cleaning liquid pipe is installed on the water outlet of the cleaning liquid valve. The end of the cleaning liquid pipe is located inside the reaction cup. The remaining end is communicated with the outlet end of the pressure regulating valve.9.根据权利要求8所述的一种全自动生化分析仪液路系统，其特征在于，所述废液收集单元包括废液收集桶和安装在废液收集桶内的第二液位传感器。9 . The liquid circuit system of an automatic biochemical analyzer according to claim 8 , wherein the waste liquid collection unit comprises a waste liquid collection barrel and a second liquid level sensor installed in the waste liquid collection barrel. 10 .10.根据权利要求9所述的一种全自动生化分析仪液路系统，其特征在于，所述废液收集桶上设置有通气孔。10 . The liquid circuit system of an automatic biochemical analyzer according to claim 9 , wherein the waste liquid collection barrel is provided with a ventilation hole. 11 .

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