Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to embodiments thereof; it should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention. Other systems, methods, and/or features of the present embodiments will become apparent to those skilled in the art upon review of the following detailed description. It is intended that all such additional systems, methods, features and advantages be included within this description, be within the scope of the invention, and be protected by the accompanying claims. Additional features of the disclosed embodiments are described in, and will be apparent from, the detailed description that follows.
The same or similar reference numerals in the drawings of the embodiments of the present invention correspond to the same or similar components; in the description of the present invention, it should be understood that if there is an orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", etc. based on the orientation or positional relationship shown in the drawings, it is only for convenience of describing the present invention and simplifying the description, but it is not intended to indicate or imply that the device or component referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and are not to be construed as limiting the present patent, and the specific meaning of the terms described above will be understood by those of ordinary skill in the art according to the specific circumstances.
The invention relates to a therapeutic device for treating Alzheimer's disease, which teaches the following examples according to the description of the figures:
the first embodiment is as follows:
a treatment device for treating alzheimer's disease as shown in fig. 1-4, comprising: the device comprises anacquisition module 1, acontrol module 2 and astimulation module 3; wherein theacquisition module 1 is configured to acquire brain waves; the brain waves are obtained through the acquisition module worn on the head, and if the type of the brain waves is not in a specified state, the brain is induced to enter the specified state through external stimulation; thecontrol module 2 is configured to receive the corresponding data acquired by theacquisition module 1, judge whether the brain wave type of the user is in a specified state, and trigger thestimulation device 3 if the brain wave type of the user is not in the specified state; thestimulation module 3 is configured to make an external stimulation to induce brain waves into a specified state;
theacquisition module 1 is used for acquiring and measuring ambient environmental factors; theacquisition module 1 transmits the acquired ambient factor information to a processor or a background server of the control module for processing, and judges whether the environment of the user meets the treatment requirement according to the processing result; the acquisition module acquires the color of the surrounding environment through video acquisition equipment, acquires the noise of the surrounding environment through a decibel meter, acquires the temperature of the surrounding environment through a temperature sensor, performs spectral analysis through a spectral detection module, acquires the vibration of the surrounding environment through a gravity acceleration sensor or a gyroscope, acquires the odor of the surrounding environment through an odor sensor, and converts the odor into a numerical value through module processing; theacquisition module 1 is also used for measuring the distance, the light intensity or the inclination angle, wherein an infrared PSD or laser measurement unit is used for measuring the distance, a photosensitive sensor is used for measuring the light intensity, and a gravity acceleration sensor is used for measuring the inclination angle; the infrared PSD or laser measuring unit carries out distance measurement and transmits the measurement result to the control module; the acquisition module is connected with the control module by an interface; the infrared PSD or laser measurement is carried out to obtain a corresponding distance value, and the distance value is transmitted to the control module; the gravity acceleration sensor, the photosensitive sensor and the related detection module are connected with the control module by adopting I2C, UART, USB and SDIO interfaces.
In a preferred aspect of the present embodiment, the apparatus further comprises an alarm module 4, and the alarm module 4 is configured to issue an alarm according to a control command of thecontrol module 2. In the preferred scheme of this embodiment, the alarm module 4 makes alarm information in different forms of sound, vibration and light emission or in different form combinations according to different signals sent by the control module; the alarm information is transmitted to other various terminals in a point-to-point or server transfer mode through wireless.
In a preferred embodiment of the present invention, thestimulation module 3 includes a first light-emitting unit 31, a second light-emitting unit 32, and a sound-emitting unit 33; wherein the firstlight emitting unit 31 is configured to be placed in an ear hole to emit first therapeutic light to a brain damaged area; the secondlight emitting unit 32 is configured to be placed in the nostril and emit second therapeutic light to the damaged area of the brain; thesound emitting unit 33 is configured to emit sound waves to the damaged area of the brain. In a preferred embodiment of this embodiment, thecontrol module 1 may adjust the irradiation intensity and wavelength of the first light-emitting unit 31 and the second light-emitting unit 32, and thecontrol module 1 may also adjust the tone and loudness of the sound-emitting unit 33.
Example two:
this embodiment should be understood to include at least all of the features of any of the embodiments described above and further described below:
photobiomodulation therapy is defined as the use of non-ionizing electromagnetic energy to trigger photochemical changes in cellular structures that accept photons. Mitochondria are particularly receptive to this process. At the cellular level, visible red and Near Infrared (NIR) energy is absorbed by mitochondria, which function to produce cellular energy called "ATP". The key to the overall process is a mitochondrial enzyme called cytochrome oxidase (a chromosome) which accepts photon energy at a specific wavelength when functioning below standard.
Mitochondria absorb low levels of visible red to near infrared light energy and convert it to ATP for use by the cells. In addition, the process generates mild oxidants, resulting in gene transcription followed by cell repair and healing. The process also unclogs the chains that are blocked by nitric oxide. Nitric oxide is then released back into the system. Nitric oxide is a molecule produced by our body that helps communicate between cells in the body. This communication occurs by transmitting signals throughout the body. In addition, nitric oxide helps to dilute blood vessels and improve blood circulation.
To achieve the above-mentioned effects, the present embodiment provides a treatment apparatus for treating alzheimer's disease, as shown in fig. 1 to 4, comprising: the device comprises anacquisition module 1, acontrol module 2 and astimulation module 3; wherein
Theacquisition module 1 is configured to acquire brain waves; the brain waves are acquired through the acquisition module worn on the head, and if the type of the brain waves is not in the designated state, the brain is induced to enter the designated state through external stimulation; the specified states include an active state and a calm state, and too long in a certain state can easily cause the reduction of the treatment effect, so that the time for balancing the active state and the calm state is needed.
Thecontrol module 2 is configured to receive the corresponding data acquired by theacquisition module 1, judge whether the brain wave type of the user is in a specified state, and trigger thestimulation device 3 if the brain wave type of the user is not in the specified state;
thestimulation module 3 is configured to make an external stimulation to induce brain waves into a specified state;
theacquisition module 1 is used for acquiring and measuring ambient environmental factors; theacquisition module 1 transmits the acquired ambient factor information to a processor or a background server of the control module for processing, and judges whether the environment of the user meets the treatment requirement according to the processing result; the environment factors are temperature, smell, color, vibration, spectrum or noise, the acquisition module acquires the color of the surrounding environment through video acquisition equipment, acquires the noise of the surrounding environment through a decibel meter, acquires the temperature of the surrounding environment through a temperature sensor, performs spectral analysis through a spectrum detection module, acquires the vibration of the surrounding environment through a gravity acceleration sensor or a gyroscope, acquires the smell of the surrounding environment through an odor sensor, and is processed into a numerical value through the module;
theacquisition module 1 is also used for measuring the distance, the light intensity or the inclination angle, wherein an infrared PSD or laser measurement unit is used for measuring the distance, a photosensitive sensor is used for measuring the light intensity, and a gravity acceleration sensor is used for measuring the inclination angle; the infrared PSD or laser measuring unit carries out distance measurement and transmits the measurement result to the control module; the acquisition module is connected with the control module by an interface;
the infrared PSD or laser measurement is carried out to obtain a corresponding distance value, and the distance value is transmitted to the control module; the gravity acceleration sensor, the photosensitive sensor and the related detection module are connected with the control module by adopting I2C, UART, USB and SDIO interfaces.
In a preferred embodiment of the present invention, thestimulation module 3 includes a first light-emittingunit 31, a second light-emittingunit 32, and a sound-emittingunit 33; wherein,
the first light-emittingunit 31 is configured to be placed in an ear hole to emit first therapeutic light to irradiate the damaged area of the brain, and the first therapeutic light is 40;
the secondlight emitting unit 32 is configured to be placed in the nostril and emit second therapeutic light to the damaged area of the brain;
thesound emitting unit 33 is configured to emit sound waves to the damaged area of the brain.
In a preferred aspect of this embodiment, thecontrol module 1 may adjust the irradiation intensity and wavelength of the first light-emittingunit 31 and the second light-emittingunit 32, and thecontrol module 1 may also adjust the tone and loudness of the sound-emittingunit 33.
When the brain is in an active state, the first and secondlight emitting units 31 and 31 preferably illuminate the damaged area of the brain with therapeutic light emitted in 40 hz strobe, which helps attention, learning and memory integration.
When the brain is in a calm state, the first light-emittingunit 31 and the second light-emitting unit preferably emit therapeutic light emitted by a 10 hz strobe to the damaged area of the brain, which helps to maintain the overall mental coordination and calm state.
Preferably, the wavelength of the therapeutic light is mainly concentrated at 780-2526 nm.
The first and second light-emittingunits 31 and 32 illuminate at least corresponding to, but not limited to, one or more regions of temporal lobe, frontal lobe, parietal lobe, occipital lobe and hippocampal structure of the brain of the patient. By the irradiation in the composite state, the irradiation intensity can be superposed at different places to meet the illumination requirements of different parts.
Preferably, the first light-emitting unit and the first sound-emitting unit are assembled into one assembly and are in control connection through thecontrol module 2.
In a preferred aspect of the present embodiment, the apparatus further comprises an alarm module 4, and the alarm module 4 is configured to issue an alarm according to a control command of thecontrol module 2.
In the preferred scheme of this embodiment, the alarm module 4 makes alarm information in different forms of sound, vibration and light emission or in different form combinations according to different signals sent by the control module; the alarm information is transmitted to other various terminals in a point-to-point or server transfer mode through wireless.
In a preferred embodiment of this embodiment, the device further includes a timing device, and the timing device starts timing after sensing a human body by using the proximity sensor, and gives a reminder when a set time is reached.
Example three:
this embodiment should be understood to include at least all of the features of any of the embodiments described above and further described below:
photobiomodulation therapy is defined as the use of non-ionizing electromagnetic energy to trigger photochemical changes in cellular structures that accept photons. Mitochondria are particularly receptive to this process. At the cellular level, visible red and Near Infrared (NIR) energy is absorbed by mitochondria, which function to produce cellular energy called "ATP". The key to the overall process is a mitochondrial enzyme called cytochrome oxidase (a chromosome) which accepts photon energy at a specific wavelength when functioning below standard.
Mitochondria absorb low levels of visible red to near infrared light energy and convert it to ATP for use by the cells. In addition, the process generates mild oxidants, resulting in gene transcription followed by cell repair and healing. The process also unclogs the chains that are blocked by nitric oxide. Nitric oxide is then released back into the system. Nitric oxide is a molecule produced by our body that helps communicate between cells in the body. This communication occurs by transmitting signals throughout the body. In addition, nitric oxide helps to dilute blood vessels and improve blood circulation.
To achieve the above-mentioned effects, the present embodiment provides a treatment apparatus for treating alzheimer's disease, as shown in fig. 1 to 4, comprising: the device comprises anacquisition module 1, acontrol module 2 and astimulation module 3; wherein
Theacquisition module 1 is configured to acquire brain waves; the brain waves are obtained through the acquisition module worn on the head, and if the type of the brain waves is not in a specified state, the brain is induced to enter the specified state through external stimulation; the specified states include an active state and a calm state, and too long in a certain state can easily cause the reduction of the treatment effect, so that the time for balancing the active state and the calm state is needed.
Thecontrol module 2 is configured to receive the corresponding data acquired by theacquisition module 1, judge whether the brain wave type of the user is in a specified state, and trigger thestimulation device 3 if the brain wave type of the user is not in the specified state;
thestimulation module 3 is configured to make an external stimulation to induce brain waves into a specified state;
the acquisition module and the control module are integrated to a soft substrate of a head-wearing structure, and the control module is connected with the stimulation module through a lead.
Theacquisition module 1 is used for acquiring and measuring ambient environmental factors; theacquisition module 1 transmits the acquired ambient factor information to a processor or a background server of the control module for processing, and judges whether the environment of the user meets the treatment requirement according to the processing result; the environment factors are temperature, smell, color, vibration, spectrum or noise, the acquisition module acquires the color of the surrounding environment through video acquisition equipment, acquires the noise of the surrounding environment through a decibel meter, acquires the temperature of the surrounding environment through a temperature sensor, performs spectral analysis through a spectrum detection module, acquires the vibration of the surrounding environment through a gravity acceleration sensor or a gyroscope, acquires the smell of the surrounding environment through an odor sensor, and is processed into a numerical value through the module;
theacquisition module 1 is also used for measuring the distance, the light intensity or the inclination angle, wherein an infrared PSD or laser measurement unit is used for measuring the distance, a photosensitive sensor is used for measuring the light intensity, and a gravity acceleration sensor is used for measuring the inclination angle; the infrared PSD or laser measuring unit carries out distance measurement and transmits the measurement result to the control module; the acquisition module is connected with the control module by an interface;
the infrared PSD or laser measurement is carried out to obtain a corresponding distance value, and the distance value is transmitted to the control module; the gravity acceleration sensor, the photosensitive sensor and the related detection module are connected with the control module by adopting I2C, UART, USB and SDIO interfaces.
In a preferred embodiment of the present invention, thestimulation module 3 includes two firstlight emitting units 31, one or two secondlight emitting units 32, and twosound emitting units 33; wherein,
the first light-emittingunit 31 is configured to be placed in an ear hole to emit first therapeutic light to irradiate the damaged area of the brain, and the first therapeutic light is 40;
the secondlight emitting unit 32 is configured to be placed in the nostril and emit second therapeutic light to the damaged area of the brain;
thesound emitting unit 33 is configured to emit sound waves to the damaged area of the brain.
The two first light-emitting units are respectively connected to the left ear and the right ear; the second light-emitting unit is provided with a breathing opening, so that the phenomenon that the nose cannot be used for breathing after the nostrils are blocked is prevented.
In a preferred embodiment of this embodiment, thecontrol module 1 may adjust the irradiation intensity, wavelength, illumination time, illumination position, and illumination range of the first light-emittingunit 31 and the second light-emittingunit 32, and thecontrol module 1 may also adjust the tone and loudness of the sound-emittingunit 33.
Theacquisition module 1 sends the change data of the brain waves to the control module, and the parameters of the light-emitting units and the parameters of the generating units are adjusted in real time through the control module.
When the brain is in an active state, the first and secondlight emitting units 31 and 31 preferably illuminate the damaged area of the brain with therapeutic light emitted in 40 hz strobe, which helps attention, learning and memory integration.
When the brain is in a calm state, the first light-emittingunit 31 and the second light-emitting unit preferably emit therapeutic light emitted by a 10 hz strobe to the damaged area of the brain, which helps to maintain the overall mental coordination and calm state.
Preferably, the wavelength of the therapeutic light is mainly concentrated at 780-2526 nm.
Preferably, the generating unit emits a sound signal of 10KHz-20KHz to the brain damage region.
The first and secondlight emitting units 31 and 32 illuminate at least corresponding to one or more regions of temporal lobe, frontal lobe, parietal lobe, occipital lobe and hippocampal structure of the brain of the patient, but not limited to these regions. By the irradiation in the composite state, the irradiation intensity can be superposed at different places to meet the illumination requirements of different parts.
Preferably, the first light-emitting unit and the first sound-emitting unit are integrated into a light-emitting earplug assembly, and are connected through thecontrol module 2.
As shown in fig. 6, the structure of the light emitting earplug is schematically illustrated, which includes: theearplug body 5 and withearplug cover 6 ofearplug body 5 complex, an insidesound emitting unit 33 that is provided with ofearplug body 5, still be provided with in theearplug body 5 firstlight emitting unit 31 and leadedlight device 51. By adopting the scheme, two treatment methods of illumination and music playing are realized, mutual interference is avoided, functional stability is very good, and two special treatment methods of illumination and music can be conveniently realized. Realizes the basic functions of the in-ear phototherapy instrument, and has the advantages of better stability, more functions, better practicability and adaptability.
Theearplug body 5 comprises acylindrical shell 51 which runs through an inner cavity, the inner cavity wall of the shell is provided with thesound generating unit 33, the sound generating unit comprises aconventional voice coil 331 and adiaphragm 332, the inner cavity middle part of theshell 51 is provided with the firstlight emitting unit 31, the firstlight emitting unit 31 comprises an edge, theearplug sleeve 6 reaches theshell 51, the direction of theshell 51 is sequentially provided with a reflective threadedlens 52, alight emitting source 53 and a diffraction collection threadedreflective membrane 54, the reflective threadedlens 52 is far away from one end of thelight emitting source 53 is provided with areflective collection reflector 55, thelight emitting source 53 is connected with a power supply through a wire, the wire is connected with the tail end of theshell 51 through a rotatable structure, theshell 51 is provided with a clearance position for the wire to be rotatably matched, and the wire is positioned on theshell 51, the position of thelight emitting source 53 can be conveniently adjusted. Thediaphragm 332 and the diffraction collection threadedreflective film 54 are integrally disposed, and in order to prevent the poor sound effect caused by the insignificant vibration after the connection between thediaphragm 332 and the diffraction collection threadedreflective film 54, in a preferred embodiment of the present invention, a magnetic structure is further disposed on the peripheries of thediaphragm 332 and the diffraction collection threadedreflective film 54, and the magnetic structure is used for increasing the vibration effect of thediaphragm 332. The magnetic structure is a common structure of the earplug, and is not described in detail herein.
Specifically, light emittingsource 53 transmits light to the ear canal through the through inner cavity ofhousing 51, and light becomes parallel light throughreflective screw lens 52, thereby better utilizing the reflective ear canal wall in the ear canal to transmit light, but this is only an ideal state, and light can be diffracted and reflected to lose, and a large amount of reflected light is retransmitted to the ear canal through reflective collectingreflector 55, and the absorption ofhousing 51 to light is avoided through diffractive collecting screwreflective membrane 54, thereby better light with transmitting becomes parallel light and reflects back to the ear canal, thereby realizing the maximized utilization of light, and reducing light loss.
As shown in fig. 6, in this embodiment, a reflective film is added on the light-emitting earplug, so as to avoid light leakage and light loss of the light-emitting earplug. In particular, the threaded reflective film is capable of reflecting a variety of light sources of different frequencies and wavelengths, pulses or continuum including, but not limited to, one or more visible, invisible lights emitted by the light emitting earplugs. The thread reflecting film is arranged in the light-emitting earplug and is not limited to the inner surface or the outer surface of the rubber plug or the middle layer of the rubber plug. The thread reflecting film reflects light rays in the luminous earplug equipment so as to improve the reflection efficiency of the light and obviously improve the effect of the light on treating various diseases. The thread reflecting film of the luminous earplug has the advantage and characteristic that the structure of the original luminous earplug is not required to be changed. And (3) a thread reflection film: the position of the emitter film is not limited to the inner, outer or middle layer of the light therapy earplug; the efficiency of the light-emitting earplug for reflecting light is improved. A light emitting source: the threaded reflective film is capable of reflecting one or more of a plurality of visible, invisible, different frequencies and wavelengths, pulsed or continuous light sources emitted by the light emitting earplug. Providing sufficient power to the headset. The arrangement of the threaded reflective film on the light-emitting earplug as shown in fig. 6 is not limited to the inner surface and the outer surface of the rubber plug or the middle layer of the rubber plug. The light source that the thread reflection film can emit includes but is not limited to one or more visible, invisible light, various frequencies and wavelengths, pulses or continuous multiple light sources. The light source is installed and fixed in the through hole, and the position of the light emitting device is not limited to the light source being internally arranged, externally arranged and the like. The earplug uses with the body of luminous earplug mutually supporting, the earplug with around set up an annular groove on the earphone surface, the earphone cover the annular groove on, earplug shape and material include and are not limited to the bellied rubber buffer cylinder of one end, gasbag earplug, sponge earplug etc.. The control wire is led out from the side wall of the earphone body and is connected with the power supply of the luminous earplug.
As shown in fig. 7, a schematic structural diagram of the second light emitting unit 32 is shown, which includes: an elastic shell 321 having an open end and an accommodating chamber formed therein, and a holding portion 322 connected to the open end; the luminous earplug is characterized by further comprising a luminous structure 323 accommodated in the accommodating cavity, a breathing valve 323 detachably connected to the clamping part 322, communicated with external air and the accommodating cavity, a plurality of vent holes 324 formed in the peripheral wall of the elastic shell 321 and communicated with the accommodating cavity, and a through hole 325 for light emission located at the top of the accommodating cavity, wherein the luminous structure 323 comprises a shell 3231, a light reflection collection reflector 55 connected to the shell 3231 and close to one end of the through hole 325 for light emission, a light reflection screw lens 52, a light emitting source 53 and a diffraction collection screw thread reflection film 54 sequentially arranged in the inner cavity of the shell 3231, and meanwhile, the clamping part 322 is further connected with a residual light collection screw thread reflection film 56, each screw thread reflector and the screw thread reflection film act on the consistency among the luminous earplugs, and the residual light lost from the vent holes is reflected by the residual light collection screw thread reflection film 56, thereby realizing the maximum utilization of light and reducing the light loss.
Thelight emitting sources 53 of the firstlight emitting unit 31 and the secondlight emitting unit 32 may be LED lamps, and their structures are common structures in the prior art and are not described herein again. The following models or types of thesound generating unit 33 can be selected: CD4020B, Ti; AiP555, Wuxi I-CORE; SN74LVC1G79DBVR, Ti; GS8722, a semiconductor. Meanwhile, thesound generating unit 33 can be used in cooperation with a sound power amplifying module, and the model or type thereof is as follows: LPA4890, LowPowerSemi.
In a preferred aspect of the present embodiment, the apparatus further comprises an alarm module 4, and the alarm module 4 is configured to issue an alarm according to a control command of thecontrol module 2.
In the preferred scheme of this embodiment, the alarm module 4 makes alarm information in different forms of sound, vibration and light emission or in different form combinations according to different signals sent by the control module; the alarm information is transmitted to other various terminals in a point-to-point or server transfer mode through wireless.
In a preferred embodiment of this embodiment, the device further includes a timing device, and the timing device starts timing after sensing a human body by using the proximity sensor, and gives a reminder when a set time is reached.
In conclusion, the invention provides a treatment device for treating alzheimer's disease, which has good effects of treating, relieving and inhibiting alzheimer's disease, and the output stroboscopic signal and sound signal can effectively reduce the accumulation of amyloid A beta of alzheimer's disease patients after the alzheimer's disease patients use the treatment device for a period of time, activate microglia cells, reduce nerve entanglement, effectively improve the cognitive ability and memory ability of the patients, and enhance the gamma brain waves of the patients.
Although the invention has been described above with reference to various embodiments, it should be understood that many changes and modifications may be made without departing from the scope of the invention. That is, the methods, systems, and devices discussed above are examples. Various configurations may omit, substitute, or add various procedures or components as appropriate. For example, in alternative configurations, the methods may be performed in an order different than that described, and/or various components may be added, omitted, and/or combined. Moreover, features described with respect to certain configurations may be combined in various other configurations, as different aspects and elements of the configurations may be combined in a similar manner. Further, elements therein may be updated as technology evolves, i.e., many elements are examples and do not limit the scope of the disclosure or claims.
Specific details are given in the description to provide a thorough understanding of the exemplary configurations including implementations. However, configurations may be practiced without these specific details, e.g., well-known circuits, processes, algorithms, structures, and techniques have been shown without unnecessary detail in order to avoid obscuring the configurations. This description provides example configurations only, and does not limit the scope, applicability, or configuration of the claims. Rather, the foregoing description of the configurations will provide those skilled in the art with an enabling description for implementing the described techniques. Various changes may be made in the function and arrangement of elements without departing from the spirit or scope of the disclosure.
It is intended that the foregoing detailed description be regarded as illustrative rather than limiting, and that it be understood that it is the following claims, including all equivalents, that are intended to define the spirit and scope of this invention. The above examples are to be construed as merely illustrative and not limitative of the remainder of the disclosure. After reading the description of the invention, the skilled person can make various changes or modifications to the invention, and these equivalent changes and modifications also fall into the scope of the invention defined by the claims.