CN111189663A - A cold box blade clamping device for a frozen microtome - Google Patents

Abstract

Translated fromChinese

一种冰冻切片机用冷箱刀片夹持装置，属于冰冻切片机技术领域。所述冰冻切片机用冷箱刀片夹持装置，包括本体外壳，所述本体外壳内壁底部的一侧端固定安装有主控器，且主控器电连接外部电源，所述本体外壳内壁底部的中心位置处固定安装有定位座，所述定位座的顶部滑动连接有夹持器，所述夹持器的顶部卡接有刀片，所述夹持器的侧壁上分别开设有第三通孔和第四通孔。本发明通过在夹持器的左右两侧壁上固定安装第一步进电机和第二步进电机，并通过PLC主控器控制，自动将刀片夹持器左移或右移，确保冰冻切片机的切片完整，使得切片的厚度均匀，无刀片痕迹、无褶皱，提高了组织的切片质量，减了冰冻诊断误差。

The invention relates to a cold box blade clamping device for a frozen microtome, belonging to the technical field of the frozen microtome. The cold box blade clamping device for the cryostat includes a body shell, a main controller is fixedly installed at one end of the bottom of the inner wall of the body shell, and the main controller is electrically connected to an external power supply, and the bottom of the inner wall of the body shell is fixedly installed with a main controller. A positioning seat is fixedly installed at the central position, the top of the positioning seat is slidably connected with a holder, the top of the holder is clamped with a blade, and the side walls of the holder are respectively provided with third through holes and the fourth through hole. In the invention, the first stepper motor and the second stepper motor are fixedly installed on the left and right side walls of the holder, and controlled by the PLC main controller to automatically move the blade holder to the left or right to ensure frozen slices. The machine's slicing is complete, so that the thickness of the slice is uniform, and there is no blade trace or wrinkle, which improves the quality of the tissue slice and reduces the freezing diagnosis error.

Description

Cold box blade clamping device for frozen slicer

Technical Field

The invention relates to the technical field of frozen slicers, in particular to a cold box blade clamping device for a frozen slicer.

Background

The freezing microtome is mainly used for quick pathological diagnosis of fresh tissue in operation, determining the nature of pathological changes, whether tumor has metastasis or not and whether the stump has pathological changes or not, and providing reliable basis for surgical treatment. High quality cryo-sections and fast throughput are therefore of great importance. And the slicing process of the frozen microtome is as follows: firstly, placing tissues on a tissue support, wrapping the tissues by using an embedding medium OCT, then quickly placing the tissues on a freezing table for freezing, after several minutes to tens of minutes, the tissues are frozen, and clamping the support with the frozen tissues on a microtome holder, so that the microtome can be used for repairing and slicing.

However, due to the hardness of the tissue cryo-section, the sharpness of the blade is significantly impaired at the original section position and the significant serrations are visible under the microscope over a period of time during sectioning, and the integrity of the section is only guaranteed when the blade is moved to a new position. The automatic moving device for the blade holder in the freezing box of the freezing microtome is not provided in the prior art, the existing moving blade adopts the manual operation of a user to stretch into the freezing box, the locking rod is lightly moved, the blade holder is moved leftwards or rightwards, and then the locking rod is manually locked, so that the film making time is prolonged, the temperature in the freezing box is influenced, the time for waiting for a diagnosis result of a patient is greatly prolonged, and the practicability is limited.

Disclosure of Invention

In order to solve the technical problems that slicing and flaking time is long and a cold box blade holder in a frozen slicer cannot automatically move in the prior art, the invention provides a cold box blade holding device for a frozen slicer, which comprises a body shell, wherein a main controller is fixedly arranged at one side end of the bottom of the inner wall of the body shell, the main controller is electrically connected with an external power supply, a positioning seat is fixedly arranged at the central position of the bottom of the inner wall of the body shell, the top of the positioning seat is connected with the holder in a sliding manner, a blade is clamped at the top of the holder, a third through hole and a fourth through hole are respectively arranged on the side wall of the holder, the third through hole is arranged above the fourth through hole, a first through hole and a second through hole are respectively arranged on the left side wall and the right side wall of the body shell, the first through hole is arranged above the second through hole, and a, the first box body is of a box body structure with an opening at one end, a first stepping motor is fixedly mounted on the inner wall of the first box body, the output end of the first stepping motor is fixedly connected with a first lead screw, the first lead screw penetrates through a first through hole and a third through hole and extends to the outer side of the clamp holder, a first electric switch is fixedly connected to the top of the first box body, the input end of the electric switch is electrically connected with an external power supply, the output end of the first electric switch is electrically connected with the first stepping motor, a second through hole is screwed on the outer side wall of the shell of the body and is connected with a second box body, a second stepping motor is fixedly mounted on the inner wall of the second box body, the second stepping motor is electrically connected with a main controller, the output end of the second stepping motor is fixedly connected with a second lead screw, the second lead screw penetrates through the second through hole and the fourth through hole and extends to the outer side of the clamp, the main controller is connected to the reduction gear electricity, and the other end of locking sleeve is located the fourth through hole, the front surface fixed mounting of body shell has visual window and voice operation unit, and voice operation unit electricity connection main controller.

As a further improvement of the invention, the positioning seat comprises a small hole and a raised line, the bottom of the holder is provided with a first sliding groove and a second sliding groove, the inner wall of the first sliding groove is connected with a sliding column in a sliding manner, the sliding column is clamped in the small hole, and the raised line is clamped in the second sliding groove.

As a further improvement of the invention, the first through hole and the third through hole are positioned on the same horizontal plane, and the second through hole and the fourth through hole are positioned on the same upper plane.

As a further improvement of the invention, the bottom of the body shell is fixedly provided with a supporting seat, and the bottom of the supporting seat is sleeved with a rubber pad.

As a further improvement of the invention, the master controller is a PLC controller.

As a further improvement of the invention, an air cooler is fixedly arranged at the center of the top of the inner wall of the body shell.

As a further improvement of the invention, the front surface of the body shell is also fixedly connected with a second electric switch, the input of the second electric switch is electrically connected with an external power supply, and the output of the second electric switch is electrically connected with an air cooler.

As a further improvement of the invention, the voice operation unit comprises a voice acquisition unit and a voice recognition unit.

As a further improvement of the present invention, the voice collecting unit is specifically a microphone or a microphone, and the voice recognizing unit is specifically a voice recognizing chip.

Has the advantages that: according to the invention, the first stepping motor and the second stepping motor are fixedly arranged on the left side wall and the right side wall of the holder, the first stepping motor and the second stepping motor are controlled by the voice operation system to drive the first lead screw and the second lead screw to rotate, the blade holder is controlled by the PLC master controller to automatically open the locking sleeve and automatically move the blade holder leftwards or rightwards, so that the completeness of the slice of the frozen slicer is ensured, the slice is uniform in thickness and free from blade marks and wrinkles, the slicing quality of tissues is improved, the frozen diagnosis error is reduced, the slice making time is greatly shortened, the diagnosis time of a surgeon and the time of a patient waiting for a diagnosis result are also reduced, and the practicability of the frozen slicer is enhanced.

Drawings

FIG. 1 is a schematic structural view of a cold box blade clamping device for a cryo-microtome according to the present invention;

FIG. 2 is a front view of a cold box blade holding device for a cryo-microtome according to the present invention;

FIG. 3 is a schematic structural diagram of a positioning seat in a cold box blade clamping device for a frozen slicer according to the present invention;

FIG. 4 is a schematic structural view of the bottom of a holder in a cold box blade holding device for a frozen slicer according to the present invention;

FIG. 5 is a left side view of a holder of the cold box blade holding device for a frozen slicer according to the present invention;

FIG. 6 is a circuit flow diagram of a cold box blade clamping device for a cryo-slicer according to the present invention;

FIG. 7 is a block diagram of a flow chart of a voice operation unit in the cold box blade clamping device for the ice slicer according to the present invention.

1. The body shell, 2, a supporting seat, 3, a rubber pad, 4, an air cooler, 5, a master controller, 6, a positioning seat, 601, a small hole, 602, a convex strip, 7, a clamping device, 701, a third through hole, 702, a fourth through hole, 703, a first sliding chute, 704, a second sliding chute, 8, a blade, 9, a first through hole, 10, a first box body, 11, a second through hole, 12, a second box body, 13, a second stepping motor, 14, a second lead screw, 15, a speed reducer, 16, a locking sleeve, 17, a first stepping motor, 18, a first electric switch, 19, a first lead screw, 20, a visible window, 21, a second electric switch, 22, a voice operation unit, 2201, a voice acquisition unit, 2202, a voice recognition unit, 23, a sliding column.

Detailed Description

The present invention is described in detail with reference to the embodiments shown in the drawings, but it should be understood that these embodiments are not intended to limit the present invention, and those skilled in the art should understand that functional, methodological, or structural equivalents or substitutions made by these embodiments are within the scope of the present invention.

As shown in figure 1, the invention provides a cold box blade clamping device for a frozen slicer, which comprises abody shell 1, in order to more stably fix the cold box blade clamping device and prevent the blade clamping device from being damaged in the carrying process, a supportingseat 2 is fixedly arranged at the bottom of thebody shell 1, arubber pad 3 is sleeved at the bottom of the supportingseat 3, anair cooler 4 is fixedly arranged at the central position of the top of the inner wall of thebody shell 1, theair cooler 4 is used for blowing off cut sample slices and preventing the next slicing from being blocked, amain controller 5 is fixedly arranged at one side of the bottom of the inner wall of thebody shell 1, themain controller 5 is electrically connected with an external power supply, themain controller 5 is a conventional PLC (programmable logic controller) controller, such as a Siemens S-400, themain controller 5 is used for processing and analyzing various information to realize control, apositioning seat 6 is fixedly arranged at the central position of the bottom of, the top of thepositioning seat 6 is slidably connected with aholder 7, as shown in fig. 3, thepositioning seat 6 includes asmall hole 601 and aconvex strip 602, as shown in fig. 4, the bottom of theholder 7 is provided with afirst chute 703 and asecond chute 704, the inner wall of thefirst chute 703 is slidably connected with aslide column 23, theslide column 23 is clamped in thesmall hole 601, the convexstrip 602 is clamped with thesecond chute 704, the top of theholder 7 is clamped with ablade 8, as shown in fig. 5, the side wall of theholder 7 is respectively provided with a third throughhole 701 and a fourth throughhole 702, the third throughhole 701 is located above the fourth throughhole 702, the left and right side walls of thebody housing 1 are respectively provided with a first through hole 9 and a second throughhole 11, the first through hole 9 is located above the second throughhole 11, the first through hole 9 and the third throughhole 701 are located on the same horizontal plane, the second throughhole 11 and the fourth throughhole 702 are located on, the first through hole 9 is positioned on the outer side wall of thebody shell 1 and is in screwed connection with afirst box body 10, thefirst box body 10 is of a box body structure with one open end, the inner wall of thefirst box body 10 is fixedly provided with a first steppingmotor 17, the output end of thefirst stepping motor 17 is fixedly connected with afirst lead screw 19, thefirst lead screw 19 penetrates through the first through hole 9 and a third throughhole 701 and extends to the outer side of theclamp holder 7, the top of thefirst box body 10 is fixedly connected with a firstelectric switch 18, the input end of theelectric switch 18 is electrically connected with an external power supply, as shown in figure 6, the output end of the firstelectric switch 18 is electrically connected with thefirst stepping motor 17, the second throughhole 11 is positioned on the outer side wall of thebody shell 1 and is in screwed connection with asecond box body 12, the inner wall of thesecond box body 12 is fixedly provided with asecond stepping motor 13, and the, the output end of thesecond stepping motor 13 is fixedly connected with asecond lead screw 14, thesecond lead screw 14 penetrates through the second throughhole 11 and the fourth throughhole 702 and extends to the outside of theholder 7, the outer wall of thesecond lead screw 14 is sequentially and fixedly provided with aspeed reducer 16 and alocking sleeve 16, thespeed reducer 16 is used for controlling thesecond stepping motor 13 and preventing thesecond stepping motor 13 from being damaged, thespeed reducer 16 is electrically connected with amain controller 5, the other end of thelocking sleeve 16 is positioned in the fourth throughhole 702, as shown in fig. 2, the front surface of thebody shell 1 is fixedly provided with avisible window 20, avoice operation unit 22 and a secondelectric switch 21, thevoice operation unit 22 is electrically connected with themain controller 5, the input of the secondelectric switch 21 is electrically connected with an external power supply, the output of the secondelectric switch 21 is electrically connected with theair cooler 4, as shown in fig. 7, thevoice operation unit 22 comprises a voice acquisition unit 220, thevoice acquisition unit 2201 is specifically a microphone or a microphone, thevoice acquisition unit 2201 is used for sensing voice signals in different environments and performing corresponding filtering processing on the voice signals to obtain accurate and clear voice signals, and transmitting the voice signals to thevoice recognition unit 2202, thevoice recognition unit 2202 is specifically a voice recognition chip, thevoice recognition unit 2202 recognizes the voice signals acquired by thevoice acquisition unit 2201 by using a recognition algorithm existing on the market and matches the recognized voice signals with preset voice operation phrases to obtain voice operation instructions corresponding to the voice signals, and transmits the operation instructions to themain controller 5, so that themain controller 5 performs corresponding control.

The working principle is as follows: when the invention is used, firstly, an external power supply is switched on, a user firstly presses a secondelectric switch 21, the secondelectric switch 21 controls acold air blower 4 to start, in the slicing process, when ablade 8 on a holder needs to be moved, the user speaks a preset voice signal such as 'left shift' or 'right shift' to avoice operation unit 22, at the moment, avoice acquisition unit 2201 in thevoice operation unit 22 acquires the voice signal sent by the user in the environment and correspondingly filters the voice signal to obtain an accurate and clear voice signal, after filtering, the voice signal is transmitted to avoice recognition unit 2202, a voice recognition chip in thevoice recognition unit 2202 recognizes the voice signal acquired by thevoice acquisition unit 2201 through a recognition algorithm and matches the recognized voice signal with a preset voice operation phrase or signal, so as to obtain a voice operation instruction corresponding to the voice signal, and transmit the operation instruction to themain controller 5, if the recognition is successful, themain controller 5 controls thesecond stepping motor 13 to rotate for a certain time, the second steppingmotor 13 rotates to drive thesecond lead screw 14 to rotate, and further drive thelocking sleeve 16 to loosen, at this time, the user manually presses the firstelectric switch 18, controls the first steppingmotor 17 to rotate, and drives thefirst lead screw 19 to rotate, and further drives theblade 8 at the top of theholder 7 to move in the horizontal direction by sliding the raisedstrip 602 on the secondsliding groove 704, so as to realize the left movement or the right movement of theblade 8, when theblade 8 at the top of theholder 7 moves to a proper position, the user loosens the pressed firstelectric switch 18, controls the first steppingmotor 17 to stop rotating, and simultaneously speaks a preset voice signal to thevoice operation unit 22, if the user locks or finishes, thevoice operation unit 22 transmits the voice signal to themain controller 5 again through the collection of thevoice collection unit 2201 and the recognition of thevoice recognition unit 2202, themain controller 5 controls thesecond stepping motor 13 to rotate in the opposite direction, and then thelocking sleeve 16 is driven to lock theholder 7 again.

The above embodiments of the present invention show the structure of the cold box blade holding device for a cryomicrotome, and the structure and principle of the present invention can be applied to the blade holding device of a tissue paraffin microtome as well.

In the above embodiments of the present invention, thefirst stepping motor 17 is used to drive thefirst lead screw 19 to rotate, and thesecond stepping motor 13 is used to drive thesecond lead screw 14 to rotate, and also based on the principle of the present invention, other conventional driving manners may be used, and all of them fall within the protection scope of the present invention.

It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (9)

Translated fromChinese

1.一种冰冻切片机用冷箱刀片夹持装置，包括本体外壳(1)，其特征在于：所述本体外壳(1)内壁底部的一侧端固定安装有主控器(5)，且主控器(5)电连接外部电源，所述本体外壳(1)内壁底部的中心位置处固定安装有定位座(6)，所述定位座(6)的顶部滑动连接有夹持器(7)，所述夹持器(7)的顶部卡接有刀片(8)，所述夹持器(7)的侧壁上分别开设有第三通孔(701)和第四通孔(702)，且第三通孔(701)位于第四通孔(702)的上方，所述本体外壳(1)的左右两侧壁分别开设有第一通孔(9)和第二通孔(11)，且第一通孔(9)位于第二通孔(11)上方，所述第一通孔(9)位于本体外壳(1)的外侧壁上螺接有第一箱体(10)，且第一箱体(10)为一端开口的箱体结构，所述第一箱体(10)的内壁固定安装有第一步进电机(17)，所述第一步进电机(17)的输出端固定连接第一丝杠(19)，且第一丝杠(19)贯穿第一通孔(9)和第三通孔(701)延伸至夹持器(7)外侧，所述第一箱体(10)的顶部固定连接有第一电动开关(18)，且电动开关(18)的输入端电连接外部电源，所述第一电动开关(18)的输出端电连接第一步进电机(17)，所述第二通孔(11)位于本体外壳(1)的外侧壁上螺接有第二箱体(12)，所述第二箱体(12)的内壁固定安装有第二步进电机(13)，且第二步进电机(13)电连接主控器(5)，所述第二步进电机(13)的输出端固定连接第二丝杠(14)，且第二丝杠(14)贯穿第二通孔(11)和第四通孔(702)延伸至夹持器(7)外侧，所述第二丝杠(14)的外壁依次固定安装有减速器(16)和锁紧套筒(16)，所述减速器(16)电连接主控器(5)，且锁紧套筒(16)的另一端位于第四通孔(702)内，所述本体外壳(1)的前表面固定安装有可视窗口(20)和语音操作单元(22)，且语音操作单元(22)电连接主控器(5)。1. A cold box blade clamping device for a frozen microtome, comprising a body casing (1), characterized in that: a main controller (5) is fixedly installed at one side end of the inner wall bottom of the body casing (1), and The main controller (5) is electrically connected to an external power source, a positioning seat (6) is fixedly installed at the central position of the bottom of the inner wall of the body shell (1), and a holder (7) is slidably connected to the top of the positioning seat (6). ), the top of the holder (7) is clamped with a blade (8), and the side wall of the holder (7) is respectively provided with a third through hole (701) and a fourth through hole (702) , and the third through hole (701) is located above the fourth through hole (702), the left and right side walls of the main body shell (1) are respectively provided with a first through hole (9) and a second through hole (11) , and the first through hole (9) is located above the second through hole (11), the first through hole (9) is located on the outer side wall of the main body shell (1), and the first box body (10) is screwed, and The first box body (10) is a box body structure with one end open, the inner wall of the first box body (10) is fixedly mounted with a first step motor (17), and the output of the first step motor (17) The end is fixedly connected to the first lead screw (19), and the first lead screw (19) extends through the first through hole (9) and the third through hole (701) to the outside of the holder (7), the first box A first electric switch (18) is fixedly connected to the top of the body (10), the input end of the electric switch (18) is electrically connected to an external power source, and the output end of the first electric switch (18) is electrically connected to the first step motor (17), the second through hole (11) is located on the outer side wall of the main body shell (1) and is screwed with a second box (12), and the inner wall of the second box (12) is fixedly mounted with a second box (12). A stepper motor (13), and the second stepper motor (13) is electrically connected to the main controller (5), the output end of the second stepper motor (13) is fixedly connected to the second lead screw (14), and the first The two lead screws (14) extend through the second through hole (11) and the fourth through hole (702) to the outside of the holder (7). The outer wall of the second lead screw (14) is sequentially fixed with a reducer ( 16) and a locking sleeve (16), the speed reducer (16) is electrically connected to the main controller (5), and the other end of the locking sleeve (16) is located in the fourth through hole (702), the A visual window (20) and a voice operating unit (22) are fixedly installed on the front surface of the body casing (1), and the voice operating unit (22) is electrically connected to the main controller (5).2.根据权利要求1所述的一种冰冻切片机用冷箱刀片夹持装置，其特征在于，所述定位座(6)包括小孔(601)和凸条(602)，所述夹持器(7)的底部开设有第一滑槽(703)和第二滑槽(704)，所述第一滑槽(703)的内壁滑动连接滑柱(23)，且滑柱(23)卡接在小孔(601)内，所述凸条(602)卡接第二滑槽(704)。2 . The cold box blade clamping device for a cryostat according to claim 1 , wherein the positioning seat ( 6 ) comprises a small hole ( 601 ) and a protruding line ( 602 ), and the clamping The bottom of the device (7) is provided with a first chute (703) and a second chute (704). Connected in the small hole (601), the protruding strip (602) is clamped to the second chute (704).3.根据权利要求1所述的一种冰冻切片机用冷箱刀片夹持装置，其特征在于，所述第一通孔(9)和第三通孔(701)位于同一水平面，所述第二通孔(11)和第四通孔(702)位于同一上平面。3. The cold box blade clamping device for a cryostat according to claim 1, wherein the first through hole (9) and the third through hole (701) are located on the same horizontal plane, and the first through hole (9) and the third through hole (701) are located on the same horizontal plane. The second through hole (11) and the fourth through hole (702) are located on the same upper plane.4.根据权利要求1所述的一种冰冻切片机用冷箱刀片夹持装置，其特征在于，所述本体外壳(1)的底部固定安装有支撑座(2)，所述支撑座(3)的底部套接有橡胶垫(3)。4. The cold box blade clamping device for a cryostat according to claim 1, wherein a support seat (2) is fixedly installed at the bottom of the main body shell (1), and the support seat (3) ) is sleeved with a rubber pad (3).5.根据权利要求1所述的一种冰冻切片机用冷箱刀片夹持装置，其特征在于，所述主控器(5)的为PLC控制器。5 . The cold box blade clamping device for a cryostat according to claim 1 , wherein the main controller ( 5 ) is a PLC controller. 6 .6.根据权利要求5所述的一种冰冻切片机用冷箱刀片夹持装置，其特征在于，所述本体外壳(1)内壁顶部的中心位置处固定安装有冷风机(4)。6 . The cold box blade clamping device for a cryostat according to claim 5 , wherein a cooling fan ( 4 ) is fixedly installed at the center position of the top of the inner wall of the main body shell ( 1 ). 7 .7.根据权利要求6所述的一种冰冻切片机用冷箱刀片夹持装置，其特征在于，所述本体外壳(1)的前表面还固定连接有第二电动开关(21)，且第二电动开关(21)的输入电连接外部电源，所述第二电动开关(21)的输出电连接冷风机(4)。7. The cold box blade clamping device for a cryostat according to claim 6, wherein a second electric switch (21) is also fixedly connected to the front surface of the main body shell (1), and the first The inputs of the two electric switches (21) are electrically connected to an external power source, and the outputs of the second electric switches (21) are electrically connected to the cooling fan (4).8.根据权利要求1或7任一所述的一种冰冻切片机用冷箱刀片夹持装置，其特征在于，所述语音操作单元(22)包括语音采集单元(2201)和语音识别单元(2202)。8. a kind of cryostat blade clamping device according to any one of claim 1 or 7, wherein the voice operation unit (22) comprises a voice acquisition unit (2201) and a voice recognition unit ( 2202).9.根据权利要求8所述的一种冰冻切片机用冷箱刀片夹持装置，其特征在于，所述语音采集单元(2201)具体为麦克风或话筒，语音识别单元(2202)具体为语音识别芯片。9. The cold box blade clamping device for a frozen microtome according to claim 8, wherein the voice acquisition unit (2201) is specifically a microphone or a microphone, and the voice recognition unit (2202) is specifically a voice recognition unit chip.

Images