CN111000593A - Tissue biopsy negative pressure cutting device for bile duct stenosis diseases - Google Patents

Abstract

Translated fromChinese

本发明涉及医疗器械技术领域，具体涉及一种用于胆管狭窄性疾病的组织活检负压切取装置，包括操作手柄、鲁尔接头、外管、传动丝和切取装置，所述的外管与操作手柄连接，内部设有第一腔和第二腔，传动丝设置于第二腔中；所述的鲁尔接头设置于外管靠近操作手柄的一端，分为第一鲁尔接头和第二鲁尔接头，第一鲁尔接头与第一腔相通，供导丝穿过；第二鲁尔接头与第二腔相通；所述的切取装置中空，末端锋利，可拆卸的设置于传动丝的末端；所述的第二鲁尔接头连接负压装置。本发明可准确的定位病理组织的位置并切取，切取过程简单，对组织的创伤小，储样量大，且在取出的过程中样品不会丢失，得到的样品阳性检出率高，可在临床上推广应用。

The invention relates to the technical field of medical devices, in particular to a tissue biopsy negative pressure cutting device for bile duct stenosis diseases, comprising an operating handle, a Luer connector, an outer tube, a transmission wire and a cutting device. The handle is connected, a first cavity and a second cavity are arranged inside, and the transmission wire is arranged in the second cavity; the luer joint is arranged at one end of the outer tube close to the operating handle, and is divided into a first luer joint and a second luer joint. A luer connector, the first luer connector communicates with the first cavity for the guide wire to pass through; the second luer connector communicates with the second cavity; the cutting device is hollow, with a sharp end, and is detachably arranged at the end of the transmission wire ; The second luer connector is connected to the negative pressure device. The invention can accurately locate the position of the pathological tissue and cut it, the cutting process is simple, the trauma to the tissue is small, the storage volume is large, the sample will not be lost in the process of taking out, the obtained sample has a high positive detection rate, and can be used in clinical application.

Description

Tissue biopsy negative pressure cutting device for bile duct stenosis diseases

Technical Field

The invention relates to the technical field of medical instruments, in particular to a tissue biopsy negative pressure cutting device for bile duct stenosis diseases.

Background

Biliary stricture is a common clinical disease and is caused by benign stricture or malignant tumor, the benign biliary stricture is caused by injury of bile duct or inflammatory change of bile duct, or scar constriction of bile duct cavity caused after biliary tract operation, and the malignant biliary stricture is mainly caused by tumor compression. The judgment of benign and malignant properties of biliary stricture is very important for the selection of a treatment mode of a patient and the prognosis of a disease, but clinical differential diagnosis is very difficult, particularly malignant biliary stricture, the patient belongs to middle and late stages when obvious clinical manifestations appear due to atypical early symptoms, the radical surgical resection rate and survival rate are low, and the prognosis is very poor.

Endoscopic Retrograde Cholangiopancreatography (ERCP) is an important means for diagnosing and treating diseases of the pancreatic-biliary system. The ERCP can display the complete appearance of the bile ducts inside and outside the liver, but the sensitivity, specificity and accuracy of the qualitative diagnosis of the bile duct stenosis are not high enough; ultrasonic (IDUS) in the bile duct cavity under the duodenoscope can directly carry out ultrasonic in the bile duct, is closer to pathological tissues, still belongs to imaging diagnosis and cannot obtain pathological bases.

At present, the histopathological examination methods of bile duct stenosis diseases mainly include cell brushing examination under ERCP, bile drainage cytology examination, biopsy forceps examination and the like. Cytology samples can only be obtained by cell brushing examination and bile drainage cytology examination under ERCP, the positive rate is low (only 20-30%), the accuracy is poor, and the clinical diagnosis is greatly limited; the biopsy forceps inspection is a method for entering a focus of a human body through an endoscope, sampling pathological tissues and then judging the state of an illness through detecting the pathological tissues, and has high accuracy, but the biopsy forceps inspection has large wound on a patient, the sampling amount of samples is small, and the sample tissues are possibly lost in the taking process, so that larger wound is caused. Other methods such as the high cost of the oral son-mother choledochoscope, time-consuming operation, fragile and easily damaged choledochoscope body, great trauma of percutaneous transhepatic biliary biopsy, difficult operation, biliary hemorrhage and perforation, easy tumor dissemination and other risks, which cause the clinical application to be limited. In the existing clinical treatment process, a biopsy sampling device which is accurate in sampling position, large in sampling amount and small in wound of a patient does not exist all the time.

Although the invention patent "biopsy forceps with guide wire channel" (201620656702.X) discloses a biopsy forceps with guide wire channel, which can remove the bracket of the pancreatic and bile duct rapidly and efficiently and can enter the lesion of the pancreatic and bile duct for biopsy sampling. The inventor conducts comprehensive research on the device and finds that the device samples through a crocodile-shaped forceps head, but the device has the following problems due to the long biliary tract and inconsistent strictures: in order to avoid great trauma and medical accidents of a patient in the biopsy sampling process, small operation force is required to be ensured, so that the alligator-shaped forceps heads cannot be fully contacted, the scraped tissue amount is insufficient, multiple sampling is required to meet the requirement, and the injury of the patient is actually aggravated; 2. in order to ensure enough tissue scraping amount, the crocodile-shaped forceps head and the bile duct are required to be inclined at a large angle to sample, but the inclination angle and the sampling force between the forceps head and the bile duct cannot be accurately judged and controlled, so that a patient is greatly injured in the sampling process, and the instrument even penetrates through the bile duct, so that the life safety of the patient is endangered.

In order to solve the technical problems, the invention discloses a negative pressure tissue biopsy cutting device for bile duct stenosis diseases, which is accurate in sampling position, large in sampling amount and small in wound to a patient compared with biopsy forceps disclosed in the prior art.

Disclosure of Invention

A negative pressure tissue biopsy cutting device for bile duct stenosis diseases comprises an operating handle, a Ruhrjoint 6, anouter tube 7 and atransmission wire 9, wherein the operating handle consists of acore rod 1, asliding block 2 and anauxiliary push rod 3, thecore rod 1 is in a hollow rod shape, one end of the core rod is provided with internal threads, the other end of the core rod is provided with a handle ring, and the side wall of the core rod is provided with an opening; the push-aid rod 3 is arranged in thecore rod 1, theslide block 2 is nested on thecore rod 1 and can slide relative to thecore rod 1, and theslide block 2 seals thecore rod 1; one end of the push-aid rod 3 is connected to theslide block 2, and the other end is connected with atransmission wire 9; theouter pipe 7 is provided with external threads, and theouter pipe 7 is hermetically connected with thecore rod 1 through threads; theouter tube 7 is connected with the operating handle, two cavities, namely afirst cavity 12 and asecond cavity 13, are arranged inside the outer tube, and thetransmission wire 9 is arranged in thesecond cavity 13; theluer connector 6 is arranged at one end of theouter tube 7 close to the operating handle and is divided into afirst luer connector 601 and asecond luer connector 602, and thefirst luer connector 601 is communicated with thefirst cavity 12 for a guide wire to pass through; thesecond luer connector 602 is in communication with thesecond lumen 13; the negative pressure tissue biopsy cutting device also comprises acutting device 8, wherein thecutting device 8 is hollow and is detachably arranged at the tail end of thetransmission wire 9; thesecond luer connector 602 is connected with a negative pressure device, the negative pressure device can be a needle tube or a negative pressure aspirator, the tail end of thesecond luer connector 602 is hermetically connected with the negative pressure aspirator, air in thesecond cavity 13 is pumped out through the negative pressure aspirator, so that a relative negative pressure state is formed in thesecond cavity 13, the wall of the liner is closer to thecutting device 8 under the suction action of negative pressure, and the sample can be cut by pushing thecutting device 8.

Preferably, surely getdevice 8 be the syringe needle form, 8 terminal sharpness of sampling device of syringe needle form, the contact surface is little, adds the effect of negative pressure during the sample for the bile duct wall is pressed close to surely getsdevice 8, promotes gently and surely getsdevice 8 alright realize taking a sample, and is little to the injury of bile duct wall, simultaneously, the bore ofsampling device 8 of syringe needle form is big, and the inner chamber is big, can store more samples.

Preferably, surely getdevice 8 and be cylindricly, one end detachable is connected withtransmission silk 9, the other end seals, the lateral wall is equipped with two at leastbarbs 10,barb 10 with surely get 8 inner chambers of device and communicate with each other, surely get the sample tissue storage that obtains throughbarb 10 and cut and get indevice 8, surely get the cavity thatdevice 8 was sealed simultaneously and also can prevent to lose sample tissue because of surely getting 8's removal, andbarb 10's most advanced can be hung sample tissue and prevent that the tissue from losing, carry out the secondary sampling and cause the injury to the patient.

Preferably, thecutting device 8 is made of metal, alloy, ceramic, rigid plastic or other materials that can implement the present solution. Hard materials are more conducive to cutting tissue.

Preferably, thecutting device 8 is made of stainless steel.

Preferably, thebarbs 10 are made of metal, alloy or other material that will accomplish the present teachings.

Preferably, thebarbs 10 are made of stainless steel.

Preferably, the direction of thebarbs 10 can be the same as and/or opposite to the direction of pushing thecutting device 8, so that the biopsy tissue can be collected when thecutting device 8 is pushed or pulled, the operation times are reduced, the sampling amount is increased, and the harm to the patient is reduced.

Preferably, thecutting device 8 is provided with twobarbs 10 in opposite directions to facilitate collection of the biopsy tissue.

Preferably, thebarbs 10 are angled from 0 to 10 degrees with respect to the side walls of thecutting device 8.

Preferably, thebarbs 10 are angled at an angle of 3-6 degrees to the side walls of thecutting device 8.

Preferably, thebarbs 10 are angled at 5 ° to the side walls of thecutting device 8.

Preferably, thecore rod 1 is provided with scales, and medical personnel can push and pull thetransmission wire 9 according to the scales, so that the wound of a patient is reduced.

Preferably, one end of theouter tube 7 close to the operating handle is provided with a protectingsleeve 5, and the protectingsleeve 5 is sleeved on theouter tube 7.

Preferably, the cross section of theouter tube 7 is circular, oval or any other shape that can realize the technical solution.

① when using the needle-shaped cutting device 8, the medical staff will push the sampling device to the designated position according to the guide wire, thesecond luer 602 connects with the negative pressure device, thesecond cavity 13 forms the negative pressure state, the suction of the negative pressure will close the bile duct wall to thecutting device 8, push theslide block 2, make thecutting device 8 contact with the bile duct wall, and cut the pathological tissue, at the same time, under the negative pressure, the tissue got down enters thecutting device 8 cavity to store, but will not lose the sample because of the movement or angle change of thecutting device 8, ② when using thecutting device 8 with barb, the sample tissue got through thebarb 10 is stored in thecutting device 8, at the same time, the closed cavity of thecutting device 8 can also prevent from losing the sample tissue because of the movement of thecutting device 8, and the tip of thebarb 10 can catch the sample tissue to prevent the tissue from losing, carry on the secondary sampling, thecutting device 8 of the invention can accurately position of the pathological tissue and cut, the cut the tissue can be got in the high sample, the clinical application of the small cut tissue can be obtained in the process, the sample can be popularized in the process.

Drawings

FIG. 1 is a front view of a tissue biopsy negativepressure incision device 1 for biliary stricture diseases

1. A core bar; 2. a slider; 3. a push-aid rod; 5. sheathing a pipe; 6. a luer fitting; 601. a first luer fitting; 602. a second luer fitting; 7. an outer tube; 8. a cutting device; 9. a drive wire;

FIG. 2 is a front view of a tissue biopsy negativepressure incision device 2 for biliary stricture diseases

1. A core bar; 2. a slider; 3. a push-aid rod; 5. sheathing a pipe; 6. a luer fitting; 601. a first luer fitting; 602. a second luer fitting; 7. an outer tube; 8. a cutting device; 9. a drive wire; 10. a barb;

FIG. 3 partial sectional view of a tissue biopsy negative pressure cutting device for bile duct stenosis disease

12. A first chamber; 13. second chamber

Cross section of theouter tube 7 in fig. 4

Figure 5barb 10 shape

Detailed Description

The technical solutions of the present invention are described below with reference to specific examples, but the technical solutions of the present invention are not limited to the following examples, and those skilled in the art can easily modify, replace or change the technical solutions without changing the spirit of the technical solutions of the present invention, and thus the technical solutions of the present invention are within the scope of protection.

Example 1 tissue biopsy negativepressure incision device 1 for biliary stenosis disease

A negative pressure tissue biopsy cutting device for bile duct stenosis diseases comprises an operating handle, a Ruhr joint 6, an outer tube 7 and a transmission wire 9, wherein the operating handle consists of a core rod 1, a sliding block 2 and an auxiliary push rod 3, the core rod 1 is in a hollow rod shape, one end of the core rod is provided with internal threads, the other end of the core rod is provided with a handle ring, and the side wall of the core rod is provided with an opening; the push-assisted rod 3 is arranged inside the core rod 1, and the slide block 2 is nested on the core rod 1 and can slide relative to the core rod 1; one end of the boosting rod 3 is connected to the sliding block 2, and the other end of the boosting rod 3 is connected with the transmission wire 9; the outer tube 7 is provided with external threads, the outer tube 7 is connected with the core rod 1 through threads, the outer tube 7 is connected with an operating handle, two cavities, namely a first cavity 12 and a second cavity 13, are arranged inside the outer tube, and the transmission wire 9 is arranged in the second cavity 13; the luer connector 6 is arranged at one end of the outer tube 7 close to the operating handle and is divided into a first luer connector 601 and a second luer connector 602, and the first luer connector 601 is communicated with the first cavity 12 for a guide wire to pass through; the second luer connector 602 is in communication with the second lumen 13; the negative pressure tissue biopsy cutting device also comprises a cutting device 8, wherein the cutting device 8 is hollow, has a sharp tail end and is detachably arranged at the tail end of the transmission wire 9; the second luer connector 602 is connected with a negative pressure device, the negative pressure device can be a needle tube, the tail end of the second luer connector 602 is hermetically connected with the needle tube, air in the second cavity 13 is pumped out by drawing the needle tube, so that a negative pressure state is formed in the second cavity 13, the wall of the bile duct is closer to the cutting device 8 due to the negative pressure, and a sufficient tissue sample can be conveniently cut. Thecutting device 8 is made of metal steel and is in a needle head shape. Thecore bar 1 is provided with scales, and medical personnel can push and pull thetransmission wire 9 according to the scales, so that the wound to a patient is reduced. One end of theouter tube 7 close to the operating handle is provided with a protectingsleeve 5, and the protectingsleeve 5 is sleeved on theouter tube 7. The cross section of theouter tube 7 is circular.

Example 2 method of Using a tissue biopsy negativepressure incision device 1 for biliary stenosis

(1) Firstly, a medical worker puts a guide wire into a biliary-pancreatic tract of a patient, then the guide wire is inserted into afirst cavity 12 of anouter tube 7 and is threaded out through afirst luer connector 601, and then theouter tube 7 enters the biliary-pancreatic tract along the guide wire;

(2) according to the appointed position of the guide wire, the tissue biopsy negativepressure cutting device 8 is placed to the position needing sampling;

(3) thesecond luer connector 602 is connected with a negative pressure device, namely a needle cylinder, and the needle cylinder is pulled so that a negative pressure state is formed in thesecond cavity 13;

(4) the slidingblock 2 is pushed, thetransmission wire 9 connected with the slidingblock 2 is pushed out of thesecond cavity 13, thecutting device 8 is exposed in the gallbladder-pancreas cavity, after the tissue to be cut is determined, thecutting device 8 is tightly attached to the tissue, thetransmission wire 9 is pushed and pulled back and forth for multiple times, thecutting device 8 continuously cuts the tissue and stores the tissue in thecutting device 8 under the action of pushing force or pulling force, and the scale arranged on thecore rod 1 can control the pushing distance and reduce the wound;

(5) after sampling, the negative pressure cutting device is drawn out and the obtained sample is processed.

Example 3 tissue biopsy negativepressure incision device 2 for biliary stenosis disease

A negative pressure tissue biopsy cutting device for bile duct stenosis diseases comprises an operating handle, a Ruhr joint 6, anouter tube 7 and atransmission wire 9, wherein the operating handle consists of acore rod 1, a slidingblock 2 and anauxiliary push rod 3, thecore rod 1 is in a hollow rod shape, one end of the core rod is provided with internal threads, the other end of the core rod is provided with a handle ring, and the side wall of the core rod is provided with an opening; the push-assistedrod 3 is arranged inside thecore rod 1, and theslide block 2 is nested on thecore rod 1 and can slide relative to thecore rod 1; one end of the boostingrod 3 is connected to the slidingblock 2, and the other end of the boostingrod 3 is connected with thetransmission wire 9; theouter tube 7 is provided with external threads, and theouter tube 7 is connected with thecore rod 1 through threads. Thecore rod 1 is provided with scales, medical staff can push and pull thetransmission wire 9 according to the scales to reduce trauma to patients, theouter tube 7 is connected with the operating handle, two cavities, namely afirst cavity 12 and asecond cavity 13, are arranged inside the outer tube, and thetransmission wire 9 is arranged in thesecond cavity 13; theluer connector 6 is arranged at one end of theouter tube 7 close to the operating handle and is divided into afirst luer connector 601 and asecond luer connector 602, and thefirst luer connector 601 is communicated with thefirst cavity 12 for a guide wire to pass through; thesecond luer connector 602 is in communication with thesecond lumen 13; biopsy negative pressure surely get device still including surely gettingdevice 8, surely getdevice 8 be cylindricly, one end detachable is connected withtransmission silk 9, the other end seals, lateral wall integrated into one piece is equipped withbarb 10. Thecutting device 8 is made of stainless steel and is provided with twobarbs 10, and the directions of the twobarbs 10 are opposite. The included angle between thebarb 10 and the pipe wall of thecutting device 8 is 5 degrees. One end of theouter tube 7 close to the operating handle is provided with a protectingtube 5, and the protectingtube 5 is sleeved on theouter tube 7. The cross section of theouter tube 7 is circular.

Example 4 method of Using a tissue biopsy negativepressure dissection device 2 for biliary stenosis disease

(1) Firstly, a medical worker puts a guide wire into a biliary-pancreatic tract of a patient, then the guide wire is inserted into afirst cavity 12 of anouter tube 7 and is threaded out through afirst luer connector 601, and then theouter tube 7 enters the biliary-pancreatic tract along the guide wire;

(2) according to the appointed position of the guide wire, the tissue biopsy negativepressure cutting device 8 is placed to the position needing sampling;

(3) thesecond luer connector 602 is connected with a negative pressure device, namely a needle cylinder, and the needle cylinder is pulled so that a negative pressure state is formed in thesecond cavity 13;

(4) theslide block 2 is pushed, thetransmission wire 9 connected with theslide block 2 is pushed out of thesecond cavity 13, thecutting device 8 is exposed in the gallbladder-pancreas cavity, after the tissue to be cut is determined, thecutting device 8 is tightly attached to the tissue, thetransmission wire 9 is pushed and pulled back and forth for multiple times, thebarb 10 on thecutting device 8 continuously cuts the tissue and stores the tissue in thecutting device 8 under the action of pushing force or pulling force, the scale arranged on thecore rod 1 can control the pushing distance, and the wound is reduced;

(5) after sampling, the negative pressure cutting device is drawn out and the obtained sample is processed.

Claims (10)

Translated fromChinese

1.一种用于胆管狭窄性疾病的组织活检负压切取装置，包括操作手柄、鲁尔接头(6)、外管(7)和传动丝(9)，所述的外管(7)与操作手柄连接，内部设有两个腔，分别为第一腔(12)和第二腔(13)，传动丝(9)设置于第二腔(13)中；所述的鲁尔接头(6)设置于外管(7)靠近操作手柄的一端，分为第一鲁尔接头(601)和第二鲁尔接头(602)，第一鲁尔接头(601)与第一腔(12)相通，供导丝穿过；第二鲁尔接头(602)与第二腔(13)相通；其特征在于：1. a tissue biopsy negative pressure cutting device for bile duct stricture disease, comprising an operating handle, a luer connector (6), an outer tube (7) and a drive wire (9), the outer tube (7) and the The operating handle is connected, and two cavities are provided inside, which are a first cavity (12) and a second cavity (13) respectively, and the transmission wire (9) is arranged in the second cavity (13); the Luer connector (6) ) is arranged at one end of the outer tube (7) close to the operating handle, and is divided into a first Luer connector (601) and a second Luer connector (602), and the first Luer connector (601) communicates with the first cavity (12) , for the guide wire to pass through; the second luer connector (602) communicates with the second cavity (13); it is characterized in that:所述的组织活检负压切取装置还包括切取装置(8)，所述的切取装置(8)中空，设置于传动丝(9)的末端；所述的第二鲁尔接头(602)连接负压装置。The tissue biopsy negative pressure cutting device further comprises a cutting device (8), the cutting device (8) is hollow and is arranged at the end of the transmission wire (9); the second Luer connector (602) is connected to the negative pressure. pressure device.2.如权利要求1所述的组织活检负压切取装置，其特征在于，所述的切取装置(8)呈针头状，可拆卸的设置于传动丝(9)末端。2 . The negative pressure cutting device for tissue biopsy according to claim 1 , wherein the cutting device ( 8 ) is in the shape of a needle, and is detachably arranged at the end of the transmission wire ( 9 ). 3 .3.如权利要求1所述的组织活检负压切取装置，其特征在于，所述的切取装置(8)呈圆柱状，一端可拆卸的与传动丝(9)连接，另一端封闭，侧壁设有至少两个倒刺(10)。3. The tissue biopsy negative pressure cutting device according to claim 1, characterized in that, the cutting device (8) is cylindrical, one end is detachably connected with the transmission wire (9), the other end is closed, and the side wall is closed. At least two barbs (10) are provided.4.如权利要求2或3任一项所述的组织活检负压切取装置，其特征在于，所述的切取装置(8)由金属、合金、陶瓷、硬性塑料或其他可实现本技术方案的材料制成。4. The tissue biopsy negative pressure cutting device according to any one of claims 2 or 3, wherein the cutting device (8) is made of metal, alloy, ceramic, rigid plastic or other materials that can realize the technical solution. material.5.如权利要求2或3所述的组织活检负压切取装置，其特征在于：所述的操作手柄由芯杆(1)、滑块(2)和助推杆(3)组成，所述的芯杆(1)呈中空杆状，一端设有内螺纹，另一端设有手柄环，侧壁设有开口；助推杆(3)设置于芯杆(1)内部，滑块(2)嵌套在芯杆(1)上，与芯杆(1)可相对滑动；助推杆(3)一端连接在滑块(2)上，助推杆(3)的另一端连接传动丝(9)；所述的外管(7)上设有外螺纹，外管(7)和芯杆(1)通过螺纹连接。5. The tissue biopsy negative pressure cutting device according to claim 2 or 3, characterized in that: the operating handle is composed of a core rod (1), a sliding block (2) and a booster rod (3). The core rod (1) is in the shape of a hollow rod, one end is provided with an internal thread, the other end is provided with a handle ring, and the side wall is provided with an opening; the booster rod (3) is arranged inside the core rod (1), and the slider (2) It is nested on the core rod (1) and can slide relative to the core rod (1); one end of the booster rod (3) is connected to the slider (2), and the other end of the booster rod (3) is connected to the transmission wire (9). ); the outer pipe (7) is provided with an outer thread, and the outer pipe (7) and the core rod (1) are connected by threads.6.如权利要求5所述的组织活检负压切取装置，其特征在于：所述的倒刺(10)由金属或者合金制成，方向可与切取装置(8)推动的方向相同和/或相反。6. The tissue biopsy negative pressure cutting device according to claim 5, characterized in that: the barb (10) is made of metal or alloy, and the direction can be the same as the direction in which the cutting device (8) is pushed and/or on the contrary.7.如权利要求6所述的组织活检负压切取装置，其特征在于：所述的倒刺(10)与切取装置(8)侧壁的夹角为0-10°。7 . The negative pressure cutting device for tissue biopsy according to claim 6 , wherein the angle between the barb ( 10 ) and the side wall of the cutting device ( 8 ) is 0-10°. 8 .8.如权利要求7所述的组织活检负压切取装置，其特征在于：所述的倒刺(10)与切取装置(8)侧壁的夹角为3-6°。8 . The negative pressure cutting device for tissue biopsy according to claim 7 , wherein the angle between the barb ( 10 ) and the side wall of the cutting device ( 8 ) is 3-6°. 9 .9.如权利要求5所述的组织活检负压切取装置，其特征在于：所述的外管(7)靠近操作手柄的一端设置有护套管(5)，护套管(5)套在外管(7)的外表面。9. The tissue biopsy negative pressure cutting device according to claim 5, characterized in that: one end of the outer tube (7) close to the operating handle is provided with a protective sleeve (5), and the protective sleeve (5) is sleeved outside The outer surface of the tube (7).10.如权利要求5所述的组织活检负压切取装置，其特征在于：所述的外管(7)的横截面呈圆形、椭圆形或者其他任何能够实现本技术方案的形状。10 . The negative pressure cutting device for tissue biopsy according to claim 5 , wherein the cross section of the outer tube ( 7 ) is circular, oval or any other shape that can realize the technical solution. 11 .

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