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CN110951596A - Temperature control shaking table - Google Patents

Temperature control shaking table
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Publication number
CN110951596A
CN110951596ACN201910567839.6ACN201910567839ACN110951596ACN 110951596 ACN110951596 ACN 110951596ACN 201910567839 ACN201910567839 ACN 201910567839ACN 110951596 ACN110951596 ACN 110951596A
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CN
China
Prior art keywords
temperature
incubation
transmission
temperature control
module
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910567839.6A
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Chinese (zh)
Inventor
周进
师传胤
钱其军
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Chenghuang Nano Antibody Technology Co Ltd
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Shanghai Chenghuang Nano Antibody Technology Co Ltd
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Priority to CN201910567839.6ApriorityCriticalpatent/CN110951596A/en
Publication of CN110951596ApublicationCriticalpatent/CN110951596A/en
Pendinglegal-statusCriticalCurrent

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Abstract

The invention provides a temperature control shaking table, which comprises a casing, a base, an incubation device, a temperature control device, a motor and a transmission device, and is characterized in that: the motor is connected with the incubation device through the transmission device; casing upper portion is the recess shape, and the recess shape matches with the shape of hatching the device, is used for holding the device is hatched, be equipped with the transmission groove on the lateral wall of recess and the bottom surface, be used for holding transmission, the below in transmission groove is equipped with the water drainage tank that is used for receiving the comdenstion water that is dripped by the transmission groove that sets up on the base. The invention combines the structural design of the drainage module on the basis of the existing temperature control shaking table, and can effectively protect the circuit.

Description

Temperature control shaking table
Technical Field
The invention belongs to the field of biomedical equipment, and particularly relates to a temperature control shaking table.
Background
In cellular and medical applications, it is often necessary to perform an incubation reaction in which a sample is mixed with a biological agent, i.e., the mixture is kept in uniform shaking at a specific temperature during the reaction time. The conventional shaking table can only be used under the condition of normal temperature and is not provided with a temperature control system; in practical operation, especially when the reaction temperature is 0-10 ℃, the operator generally places the mixed solution and the shaking table in a temperature-controlled container, such as an incubator (with a temperature control range of 0-50 ℃) or a refrigerator for use, which is very inconvenient to operate.
Other relevant temperature control shaking tables generally adopt the technique of semiconductor accuse temperature, but when using under 0 ~ 10 ℃ low temperature condition, can produce a large amount of comdenstions water around the refrigerated chamber of hatching of semiconductor, most temperature control shaking tables structurally adopt the structure of semi-open formula, and the comdenstion water easily gets into electronic junction department, easily causes circuit fault, interrupts the flow of experiment, brings the unnecessary loss, can take place the circuit short circuit even, makes whole laboratory and other equipment cause the damage.
The invention provides a novel temperature control shaking table, which combines the structural design of a drainage module on the basis of the existing semiconductor temperature control mode and can effectively protect a circuit.
Disclosure of Invention
The invention provides a temperature control shaking table, which comprises a casing, a base, an incubation device, a temperature control device, a motor and a transmission device, and is characterized in that: the motor is connected with the incubation device through the transmission device; casing upper portion is the recess shape, and the recess shape matches with the bottom surface and the side shape of hatching the device for hold hatch the device, be equipped with the transmission groove on the lateral wall of recess and the bottom surface, be used for holding transmission, the below in transmission groove is equipped with the water drainage tank that is used for receiving the comdenstion water that is dripped by the transmission groove on setting up on the base.
In one or more embodiments, the temperature control device is disposed inside the incubation device.
In one or more embodiments, the bottom surface of the drain channel has a slope in the range of 5 ° to 60 °, preferably 10 ° to 20 °.
In one or more embodiments, the cabinet and the drain tank are each provided with a drain port, and the drain port of the cabinet is connected to the drain port of the drain tank.
In one or more embodiments, the temperature-controlled rocking platform further comprises a water collection box insertable into the housing drain for receiving water from the drain channel.
In one or more embodiments, the incubation device includes a body and a cover forming a space for containing the sample, the interior of the body and the interior of the cover being filled with a thermal insulation material, and when the cover is closed, the space for containing the sample is formed inside the incubation device.
In one or more embodiments, the temperature-controlled rocking bed comprises a drainage module, wherein the drainage slot is formed in the drainage module; the side wall of the drainage module is provided with a through hole, and a rotating shaft of the motor is connected with the transmission device through the through hole.
In one or more embodiments, the groove and the incubation device both have vertical left and right side walls without motion interference and a bottom surface with cambered surfaces in front and back and a plane surface in the middle.
In one or more embodiments, the incubation device has bearing mounts and mating bearings on opposite side walls, and the recess has bearing supports on opposite side walls that support the bearings, the bearings being rotatable on the bearing supports.
In one or more embodiments, the temperature-controlled rocking platform further comprises a control circuit for controlling the operation of the incubation module and the motor.
In some embodiments, the present invention also provides a temperature-controlled rocking platform comprising:
an incubation module for incubation of a sample;
the driving module is used for driving the incubation module to shake;
a drainage module for draining water; and
a support module for accommodating the incubation module, the driving module and the drainage module;
the supporting module comprises a base and a hollow shell, the upper part of the shell is groove-shaped, and the shape of the shell is matched with that of the incubation module; the bottom of the groove is provided with an opening, and a drainage module is arranged below the opening.
In one or more embodiments, the incubation module comprises an incubation device and a temperature control device that controls the temperature within the incubation device. In one or more embodiments, the incubation device comprises a body and a cover forming a space for containing the sample, the interior of the body and the interior of the cover can be filled with a thermal insulation material; when the cover is closed, a space for accommodating a sample is formed inside the incubation device.
In one or more embodiments, the drive module comprises a motor and a transmission device, wherein the motor is fixed on the base of the temperature-controlled shaking table; the transmission device penetrates through an opening formed in the wall of the groove, and the two ends of the transmission device are respectively connected with the motor and the incubation device, wherein the opening in the wall of the groove is connected with an opening in the bottom of the groove to form a transmission device groove.
In one or more embodiments, the transmission comprises a first link and a second link, one end of the first link is connected to the crankshaft of the motor, the other end of the first link is connected to the second link, and the other end of the second link is connected to the incubation device.
In one or more embodiments, the drain module includes a drain channel that is located below the transmission channel, the drain channel having a shape and size that matches the transmission channel.
In one or more embodiments, the bottom surface of the drain tank has an inclination of 5 ° to 60 ° so that the condensed water can flow to the drain port of the drain tank by its own weight.
In one or more embodiments, one side wall of the drain tank has a through hole through which a rotating shaft of a motor of the driving module is connected to the transmission.
Drawings
FIG. 1 shows a schematic external view of a temperature-controlled rocking platform according to the present invention.
FIG. 2 is a schematic view of the temperature-controlled rocking platform of the present invention with the housing removed.
FIG. 3 is a schematic view showing the structure of the drainage module of the temperature-controlled rocking bed of the present invention.
FIG. 4 is a schematic view showing the structure of the housing of the temperature-controlled rocking platform of the present invention.
The reference numerals in the present invention are explained as follows:
1. a temperature control shaking table; 2. a housing; 201. a casing water outlet; 202. a transmission slot; 203. a bearing support; 3. an incubation module; 301. a cover; 4. a water accumulation box; 5. a bearing; 501. a bearing fixing member; 6. a base; 7. a drainage module; 701. a water discharge tank; 702. a drain outlet of the drain tank; 8. a motor; 9. a connecting rod; 10. a control circuit.
Detailed Description
To make the features and effects of the present invention comprehensible to those skilled in the art, general description and definitions are made below with reference to terms and expressions mentioned in the specification and claims. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
The temperature control shaking table comprises an incubation module, a driving module, a supporting module and a drainage module, and the existing temperature control shaking table does not comprise the drainage module. On the basis of the existing temperature control shaking table, the structural design of the drainage module is added, so that condensed water generated when the temperature control shaking table is incubated under a low-temperature condition can be drained; and the drainage module of the invention isolates the condensed water from the circuit, thereby avoiding the occurrence of circuit faults. The temperature-controlled shaking table of the present invention may further comprise a control module.
In the temperature controlled rocking bed of the present invention, the supporting module is used for accommodating and mounting the incubation module, the driving module and the drainage module, and generally comprises a base and a casing. The interior of the housing itself forms a cavity that can be used to house a motor, control module, etc. The top of the housing is groove-shaped to accommodate the incubation device. The shape of recess and the bottom surface and the side shape phase-match of hatching the device, and the size is greater than the size of hatching the device for it can not collide with the recess when shaking or rocking to hatch the device. The support module may further comprise bearing supports provided on opposite side walls (also referred to as left and right walls) of the recess for mounting the incubation device and cooperating with bearings and bearing fixtures provided at both ends of the incubation device for allowing the bearings to rotate on the bearing supports. Fig. 2 and 4 exemplarily show thebearing 5, thebearing fixture 501 and thebearing support 203. The bottom surface of the groove is provided with an opening for leading the condensed water generated in the incubation process to flow into the drainage module below the opening. In some embodiments, an opening may be provided in either or both of the other two opposing side walls (also referred to as the front and rear walls) of the recess for the transmission of the drive module to pass through the housing to connect the incubation device and the motor of the drive module; the opening may extend to the bottom surface and connect with the opening on the bottom surface to form a transmission slot for accommodating the transmission to provide a space for the transmission to move. The shape and size of the actuator slot may be determined based on the type of actuator actually selected and the desired space for movement. The size of the slot of the actuator should be sufficient to provide the space for the actuator to move the incubator for rocking. In some embodiments, the well and the incubation device each have vertical left and right side walls, a front and back wall that is curved, and a bottom surface that is planar. Preferably, the bottom surface of the groove has a slope such that water can flow to the transmission slot by gravity. The shell can also be provided with a shell water outlet which is communicated with a water outlet of the water drainage groove of the water drainage module.
The incubation module is used for incubating samples at a controlled temperature, and comprises an incubation device and a temperature control device for controlling the temperature in the incubation device. The incubation device comprises a body and a cover forming a space for accommodating the sample, and the inside of the body and the inside of the cover can be filled with a heat insulating material. When the cover is closed, a space for accommodating a sample is formed inside the incubation device. The temperature control device may be a device conventionally used in the art for controlling temperature, i.e., a device capable of heating and cooling, including but not limited to a temperature-controlled semiconductor.
In the configuration shown in FIG. 2, theincubation module 3 comprises a box-shaped incubation device containing a heat-insulating material and a temperature control device (e.g., a temperature-controlled semiconductor) disposed inside the incubation device; acover 301 which can be opened and closed is provided above the incubation device, and a heat insulating material is provided inside thecover 301. When the cover is closed, a closed space for accommodating a sample is formed inside the incubation device, so that the temperature control is facilitated.
The driving module is used for driving the incubation device to shake or rock within a certain angle range and comprises a motor and a transmission device. The motor is usually fixed on the base of the temperature controlled shaking table. The transmission device is used for transmitting the power provided by the motor to the incubation device so as to enable the incubation device to shake or rock. The transmission device penetrates through an opening on the arc-shaped front wall or the arc-shaped rear wall of the groove of the machine shell and is arranged in the transmission device groove, one end of the transmission device is connected with the motor, and the other end of the transmission device is connected with the incubation device. In certain embodiments, a transmission suitable for use in the present invention comprises a connecting rod. For example, the transmission means may comprise a first link and a second link, one end of the first link being connected to the crankshaft of the motor and the other end being connected to the second link, the other end of the second link being connected to the incubation means.
In the temperature-controlled rocking bed shown in fig. 2-4, the driving module includes amotor 8 and a connecting rod assembly 9; themotor 8 is fixed on thebase 6, and a crankshaft of themotor 8 extends out of a through hole in the side wall of thedrainage module 7; the connecting rod assembly 9 comprises a first connecting rod and a second connecting rod, the first connecting rod is positioned at the inner side of thedrainage module 7 and is connected with amotor 8 shaft extending out of a through hole on the side wall of thedrainage module 7, and the other end of the first connecting rod is hinged with one end of the second connecting rod; the other end of the second link of the drainage module passes through the actuator slot 202 (i.e. the opening in the curved wall) in thehousing 2 and connects to the bottom of theincubation portion 3.
In the incubation process under the low-temperature condition of 0-10 ℃, condensed water is generated around the incubation device, falls into the surface of the groove of the machine shell, and is collected and flows into the groove of the transmission device. In the invention, the drainage module is used for collecting and discharging condensed water flowing into the transmission device groove. The drainage module comprises a drainage groove. The drainage channel is positioned below the transmission device channel, so that the condensed water dropped from the transmission device channel can fall into the drainage channel completely. In some embodiments, the drain channel has a drain channel outlet for drainage of condensed water in the drain channel. Preferably, the drain outlet of the drain tank is located at the junction of one end face and the bottom face of the drain tank. Preferably, the bottom surface of the drain channel has an inclination such that the condensed water can flow to the drain port of the drain channel by its own weight, and the inclination is preferably in the range of 5 ° to 60 °, more preferably 10 ° to 20 °. The shape and size of the drain channel should match the gear box so that the condensate dripping from the gear box can fall completely into the drain channel. The drain channel is typically slightly wider and longer than the transmission channel. Preferably, the projection of the gear groove onto the floor of the drainage groove falls completely within the range of the floor of the drainage groove. In certain embodiments, the transmission slot and the drain slot are both elongated. One side wall of the drainage channel can be provided with a through hole, and a crankshaft of the motor can penetrate through the through hole and is connected with one end of the transmission device. Thus, the transmission is located above the transmission groove and the drain groove. The upper ends of both side walls of the drain tank are preferably closely attached to the bottom and side surfaces of the groove to prevent water from leaking.
After being discharged from the water outlet of the water discharge groove, the condensed water can be collected by a conventional method or directly discharged from the temperature control shaking table. For example, the water outlet of the water drainage tank can be connected with a water pipe, and the water pipe passes through a through hole on the machine shell or the base to discharge condensed water out of the temperature control shaking table. In some embodiments, the shell of the temperature-controlled shaking table of the present invention has a shell water outlet, and the shell water outlet is communicated with the water outlet of the water drainage tank, so that the condensed water can be drained out of the temperature-controlled shaking table; in a preferred embodiment, the temperature controlled rocking bed of the present invention has a water collecting box which is inserted into the drainage port of the cabinet for receiving the condensed water discharged from the drainage port of the drainage channel, and the water collecting box is cleaned periodically.
Fig. 3 shows anexemplary drainage module 7; one end of thedrainage module 7 is provided with a drainagegroove drainage port 702; the bottom of thedrain tank 701 of thedrain module 7 is sloped such that the condensed water may be collected by one end of thedrain module 7 to thedrain tank outlet 702 under the force of gravity.
Fig. 4 exemplarily shows thegear notch 202 on thecabinet 2, thedrain module 7 is installed below thegear notch 202, and the condensed water dropped from thegear notch 202 can all fall into thedrain module 7.
Fig. 1 exemplarily shows acabinet drain port 201 on acabinet 2 and asump case 4 inserted into thecabinet drain port 201, thecabinet drain port 201 is communicated with a draintank drain port 702, and thesump case 4 can receive condensed water drained from the draintank drain port 702.
The temperature control shaking table further comprises a control module for controlling the operation of the incubation module and the driving module. Control circuitry commonly used in the art may be employed to control the operation of the incubation and drive modules described above. In some embodiments, the control unit comprises a display for setting the operation parameters of the temperature-controlled rocking bed and displaying the operation status of the temperature-controlled rocking bed; the display may be a touch screen display. In the example shown in fig. 2, the control module comprises acontrol circuit 10 fixed to thebase 6.
In some embodiments, the temperature-controlled rocking platforms of the present invention comprise a housing, a base, an incubation device, a temperature control device, a motor, and a transmission device. In the temperature control shaking table, a motor is connected with an incubation device through a transmission device; casing upper portion is the recess shape, and the shape of recess and the shape phase-match of hatching the device for hold and hatch the device, the wall and the bottom of recess are equipped with the transmission groove for hold transmission, are equipped with the water drainage tank that is used for receiving the comdenstion water that is dripped by the transmission groove on the base under the transmission groove. Optionally or further, the temperature-controlled rocking bed is provided with a motor disposed in the cavity inside the housing and connected to the incubation device through a transmission device. Optionally or further, a through hole is formed on one side wall of the drainage groove, and a shaft of the motor passes through the through hole to be connected with the transmission device. Optionally or further, the temperature-controlled rocking bed further comprises a control circuit, preferably provided inside the housing. Optionally or further, the temperature control device is disposed inside the incubation device. Optionally or further, the incubation device comprises a body and a cover forming a space for holding the sample; when the cover is closed, a space for accommodating the sample is formed inside the incubation device.
The temperature control shaking table has the following advantages:
1. the temperature control shaking table disclosed by the invention uses a semiconductor to control the temperature, so that the temperature is quickly controlled, and the accuracy is high;
2. the temperature control shaking table can automatically control the temperature, and can control the temperature without being placed in a specific temperature control container;
3. the temperature control shaking table effectively solves the problem of collecting condensed water when the temperature control shaking table is used at a low temperature, and avoids the damage of a circuit.
The invention will be further illustrated with reference to the following specific examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present disclosure, and that any devices and structures similar or equivalent to those described herein may be used in the present disclosure.
Examples
This example describes a temperature-controlled rocking bed according to the present invention with reference to the accompanying drawings.
As shown in FIGS. 1 and 4, the temperature-controlledrocking platform 1 includes ahousing 2. A bottom of one side wall of thehousing 2 has ahousing drain 201. The position of the side wall having thedrain port 201 of the cabinet is referred to as the front of the temperature controlledswing bed 1. Awater collecting box 4 for collecting condensed water can be inserted into thecase drain port 201. The upper part of thehousing 2 forms a recess for accommodating the incubation means 3; the groove is provided with a vertical left side wall, a vertical right side wall, a front bottom surface, a rear bottom surface, a plane bottom surface and a plane middle surface. Only one part of thetransmission device groove 202 in the groove is hollow. Thetransmission groove 202 is a long-strip-shaped opening, and the length direction of the transmission groove is consistent with the front-back direction of the temperature control shaking table, so that the transmission device can move. The swing angle of the temperature control shaking table 1 is 0-45 degrees.
As shown in fig. 2, the shape of theincubation device 3 is matched with the groove, and the incubation device has vertical left and right side walls, a bottom surface with cambered front and back and a plane middle, and acover 301 positioned above the bottom surface for forming a closed inner space in theincubation device 3. Theincubation device 3 is internally provided with a temperature control semiconductor, and can carry out temperature rise and temperature drop. As shown in fig. 2 and 4, the left and right side walls of theincubation device 3 are provided with abearing 5 and abearing fixing member 501, the left and right side walls of the groove are provided with abearing support member 203, theincubation device 3 is supported on thebearing support member 203 through thebearing fixing member 501 and thebearing 5, and thebearing 5 can rotate on thebearing support member 203.
As shown in fig. 2, thebase 6 is provided with adrainage module 7, amotor 8 and a control circuit 9. As shown in fig. 3, the bottom of thedrainage module 7 is a long strip-shapeddrainage groove 701 with a certain depth; when the temperature control shaking table is arranged on thebase 6, the length direction of thedrainage module 7 is consistent with the front-back direction of the temperature control shaking table. The middle parts of the left side wall and the right side wall of thedrainage module 7 are provided with certain depressions, and the shapes of the depressions are matched with the bottom surface of the groove of the machine shell. Thedrainage module 7 is installed below thetransmission device groove 202, and the projection of thetransmission device groove 202 on the base completely falls into the range of thedrainage module 7, so that the condensed water generated around theincubation device 301 under the low temperature condition can be collected into the groove of the machine shell, and then flows into thedrainage groove 701 of thedrainage module 7 through thetransmission device groove 202. The junction of the front wall and the bottom surface of thedrain module 7 has adrain slot outlet 702. The bottom surface of thedrain tank 701 has a certain inclination such that the end (rear end) of the bottom surface of thedrain tank 701 away from the draintank drain port 702 is higher than the end (front end) thereof close to the draintank drain port 702, and the inclination is in the range of 5 ° to 60 °, preferably in the range of 10 ° to 20 °, so that the condensed water collected in thedrain tank 701 is collected at the front end of thedrain tank 701 and is drained from the draintank drain port 702. Thedrain tank outlet 702 is communicated with thecasing outlet 201 for the condensed water to flow out. After thewater collecting box 4 is inserted into thedrainage port 201 of the cabinet, the condensed water drained from thedrainage port 702 of the drainage groove is collected in thewater collecting box 4, and thewater collecting box 4 only needs to be cleaned periodically.
As shown in fig. 2 and 3, the side wall of thedrain module 7 has a through hole, and the rotating shaft of themotor 8 extends into thedrain module 7 through the through hole and is connected to one end of the first connecting rod; the other end of the first connecting rod and one end of the second connecting rod are hinged with a connecting rod; the other end of the second link passes through thenotch 202 of the transmission mechanism and is connected with the bottom of theincubation device 3, so that the power provided by themotor 8 is transmitted to theincubation device 3, and theincubation device 3 is shaken.
All documents referred to herein are incorporated by reference into this application as if each were individually incorporated by reference. Furthermore, it should be understood that various changes and modifications can be made by those skilled in the art after reading the above disclosure, and equivalents also fall within the scope of the invention as defined by the appended claims.

Claims (10)

CN201910567839.6A2019-06-272019-06-27Temperature control shaking tablePendingCN110951596A (en)

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