CN110801318A

Movatterモバイル変換

Info

Publication number: CN110801318A
Application number: CN201910975842.1A
Authority: CN
Inventors: 于洋; 熊艳; 林鹭; 陈宇; 付平; 曾涛
Original assignee: Sichuan University
Current assignee: Sichuan University
Priority date: 2019-10-15
Filing date: 2019-10-15
Publication date: 2020-02-18
Anticipated expiration: 2039-10-15
Also published as: CN110801318B

Abstract

Translated fromChinese

本发明提供了一种锥形静脉支架，属于血管支架领域。上述锥形静脉支架包括径向支撑体和多个第二连接筋，径向支撑体包括两个环形的径向支撑筋和多个第一连接筋；径向支撑筋为波浪状，包括多个拐点；拐点数量与第一连接筋的数量相等。两个径向支撑筋拐点的个数相等，两个径向支撑筋相邻一侧的拐点分别通过第一连接筋连接，使得径向支撑体包括多个六边形的镂空孔。相邻的径向支撑体相邻一侧的拐点分别通过第二连接筋连接。多个径向支撑体的径向尺寸沿锥形静脉支架的锥度方向逐渐减小。当其放置于两端管径有一定差异的静脉血管中时，能够很好地适应上述病变血管自身的形状；从而为静脉血管不同部位提供较强的支撑力，有效对静脉血管进行支撑。

The invention provides a conical vein stent, which belongs to the field of vascular stents. The above-mentioned tapered venous stent includes a radial support body and a plurality of second connecting ribs, and the radial support body includes two annular radial support ribs and a plurality of first connecting ribs; the radial support ribs are wavy and include multiple Inflection point; the number of inflection points is equal to the number of the first connecting ribs. The number of inflection points of the two radial support ribs is equal, and the inflection points on the adjacent sides of the two radial support ribs are respectively connected by the first connecting ribs, so that the radial support body includes a plurality of hexagonal hollow holes. The inflection points on the adjacent sides of the adjacent radial supports are respectively connected by the second connecting ribs. The radial dimensions of the plurality of radial supports gradually decrease along the taper direction of the tapered venous stent. When it is placed in a venous blood vessel with a certain difference in diameters at both ends, it can well adapt to the shape of the above-mentioned diseased blood vessel itself, thereby providing strong support for different parts of the venous blood vessel and effectively supporting the venous blood vessel.

Description

Translated fromChinese

锥形静脉支架Conical vein stent

技术领域technical field

本发明涉及血管支架领域，具体而言，涉及一种锥形静脉支架。The present invention relates to the field of vascular stents, in particular to a tapered venous stent.

背景技术Background technique

支架经常被用于微创介入与外科手术中，例如提供支撑的血管支架、肠道支架，另外还包括作为营养物质载体并提供一定的尺寸结构的人工骨支架、人工器官支架等。Stents are often used in minimally invasive intervention and surgery, such as vascular stents and intestinal stents that provide support, and artificial bone stents and artificial organ stents that serve as nutrient carriers and provide a certain size and structure.

现有的血管支架基于动脉血管设计，通常采用两端直径相同的构形，尤其不能满足两端管径差异较大的长段静脉病变。Existing vascular stents are designed based on arterial blood vessels, and usually adopt a configuration with the same diameter at both ends, which cannot especially satisfy long-segment venous lesions with large differences in diameters at both ends.

发明内容SUMMARY OF THE INVENTION

本发明的目的在于提供了一种锥形静脉支架，其能够适用于两端管径差异较大的长段静脉。The purpose of the present invention is to provide a tapered vein stent, which can be applied to long-segment veins with large differences in diameters at both ends.

本发明是这样实现的：The present invention is realized in this way:

一种锥形静脉支架，包括：A tapered venous stent comprising:

多个径向支撑体，所述径向支撑体包括两个径向支撑筋和多个第一连接筋；所述径向支撑筋为波浪状，包括多个拐点；所述拐点数量与所述第一连接筋的数量相等；a plurality of radial support bodies, the radial support bodies include two radial support ribs and a plurality of first connecting ribs; the radial support ribs are wavy and include a plurality of inflection points; the number of the inflection points is the same as the number of the inflection points The number of the first connecting ribs is equal;

两个所述径向支撑筋拐点的个数相等，两个径向支撑筋相邻一侧的拐点分别通过所述第一连接筋连接，使得所述径向支撑体包括多个六边形的镂空孔；The number of inflection points of the two radial support ribs is equal, and the inflection points on the adjacent sides of the two radial support ribs are respectively connected by the first connecting ribs, so that the radial support body includes a plurality of hexagonal Hollow hole;

多个第二连接筋，相邻的所述径向支撑体相邻一侧的拐点分别通过所述第二连接筋连接；a plurality of second connecting ribs, the inflection points on the adjacent sides of the adjacent radial supports are respectively connected by the second connecting ribs;

多个所述径向支撑体的径向尺寸沿所述锥形静脉支架的锥度方向逐渐减小。The radial dimension of the plurality of radial supports gradually decreases along the taper direction of the tapered venous stent.

进一步；further;

径向支撑体的镂空孔的数量沿锥度方向依次减少。The number of hollow holes of the radial support body decreases sequentially along the taper direction.

进一步；further;

相邻径向支撑体的的楼空孔的数量差为1。The difference in the number of voids between adjacent radial supports is 1.

进一步；further;

所述第二连接筋的长度沿所述锥形静脉支架的锥形方向呈比例递减。The length of the second connecting rib decreases proportionally along the tapered direction of the tapered venous stent.

进一步；further;

所述比例的数值为0.8-0.9。The numerical value of the ratio is 0.8-0.9.

本发明的有益效果是：The beneficial effects of the present invention are:

本发明通过上述设计得到的锥形静脉支架，其整体为锥形，当其放置于两端管径有一定差异的静脉血管中时，能够很好地适应上述病变血管自身的形状；从而为静脉血管不同部位提供较强的支撑力，有效对静脉血管进行支撑。The tapered venous stent obtained by the above design in the present invention is tapered as a whole, and when it is placed in a venous blood vessel with a certain difference in diameter at both ends, it can well adapt to the shape of the diseased blood vessel itself; thus, it is a venous stent. Different parts of the blood vessels provide strong support, effectively supporting the venous blood vessels.

附图说明Description of drawings

为了更清楚地说明本发明实施方式的技术方案，下面将对实施方式中所需要使用的附图作简单地介绍，应当理解，以下附图仅示出了本发明的某些实施例，因此不应被看作是对范围的限定，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他相关的附图。In order to explain the technical solutions of the embodiments of the present invention more clearly, the following briefly introduces the accompanying drawings used in the embodiments. It should be understood that the following drawings only show some embodiments of the present invention, and therefore do not It should be regarded as a limitation of the scope, and for those of ordinary skill in the art, other related drawings can also be obtained according to these drawings without any creative effort.

图1是本发明实施方式提供的锥形静脉支架的展开图；1 is an expanded view of a tapered venous stent provided by an embodiment of the present invention;

图2是本发明实施方式提供的锥形静脉支架膨胀状态下的结构示意图。FIG. 2 is a schematic structural diagram of the conical venous stent provided in an embodiment of the present invention in an expanded state.

图标：1-径向支撑体；12-径向支撑筋；14-第一连接筋；16-拐点；2-第二连接筋。Icons: 1-radial support body; 12-radial support rib; 14-first connecting rib; 16-inflection point; 2-second connecting rib.

具体实施方式Detailed ways

为使本发明实施方式的目的、技术方案和优点更加清楚，下面将结合本发明实施方式中的附图，对本发明实施方式中的技术方案进行清楚、完整地描述，显然，所描述的实施方式是本发明一部分实施方式，而不是全部的实施方式。基于本发明中的实施方式，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施方式，都属于本发明保护的范围。In order to make the purposes, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments These are some embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

因此，以下对在附图中提供的本发明的实施方式的详细描述并非旨在限制要求保护的本发明的范围，而是仅仅表示本发明的选定实施方式。基于本发明中的实施方式，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施方式，都属于本发明保护的范围。Accordingly, the following detailed description of the embodiments of the invention provided in the accompanying drawings is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

在本发明的描述中，需要理解的是，指示方位或位置关系的术语为基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的设备或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。In the description of the present invention, it should be understood that the terms indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying what is indicated. A device or element must have a particular orientation, be constructed and operate in a particular orientation, and therefore should not be construed as limiting the invention.

在本发明的描述中，需要说明的是，术语“中心”、“上”、“下”、“左”、“右”、“竖直”、“水平”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，或者是该发明产品使用时惯常摆放的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。此外，术语“第一”、“第二”、“第三”等仅用于区分描述，而不能理解为指示或暗示相对重要性。In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship that the product of the invention is usually placed in use, only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying The device or element referred to must have a particular orientation, be constructed and operate in a particular orientation, and therefore should not be construed as limiting the invention. Furthermore, the terms "first", "second", "third", etc. are only used to differentiate the description and should not be construed as indicating or implying relative importance.

实施例：Example:

现有的血管支架多是基于动脉血管设计，其通常采用两端直径相同的形状；而病变的静脉血管，其管径往往不同，甚至于差别较大。此时，如果直接采用管径相同的支架，静脉血管难以得到有效支撑。基于此，本实施例提供了一种锥形静脉支架。Most of the existing vascular stents are designed based on arterial blood vessels, which usually adopt the shape of the same diameter at both ends; however, the diameters of diseased venous blood vessels are often different, or even greatly different. At this time, if a stent with the same diameter is directly used, it is difficult for the venous blood vessel to be effectively supported. Based on this, this embodiment provides a tapered venous stent.

请参考图1-图2；图1为架设沿锥形静脉支架的长度方向将其剪开后展开的结构示意图；图2为锥形静脉支架膨胀后的结构示意图(图中由于锥形静脉支架镂空孔的原因，后部的第二连接筋2也能显示在图2中，因此显示效果与图1中有所区别)。Please refer to Fig. 1-Fig. 2; Fig. 1 is a schematic structural diagram of erecting a conical venous stent after cutting it along its length direction and unfolding it; Because of the hollow hole, the second connectingrib 2 at the rear can also be shown in Figure 2, so the display effect is different from that in Figure 1).

锥形静脉支架包括多个径向支撑体1，其沿锥形静脉支架的长度方向依次排列分布。每个径向支撑体1包括两个径向支撑筋12和多个第一连接筋14。膨胀起来的静脉血管支架，其径向支撑筋12大致为圆环形，用于与血管的内壁贴合，并起到支撑血管的作用。径向支撑筋12被弯折成波浪状，从而形成多个波峰和波谷；为了便于描述，将波峰和波谷统称为拐点16。同一个径向支撑体1中，两个径向支撑筋12对称设置，即一个径向支撑筋12的波峰与另外一个径向支撑筋12的波谷相对设置，并通过沿锥形静脉支架的轴向延伸的第一连接筋14连接。径向支撑体1与第一连接筋14的连接使得径向支撑体1包括多个大致为六边形的镂空孔。The conical venous stent includes a plurality of radial supports 1, which are arranged and distributed in sequence along the length direction of the conical venous stent. Each radial support body 1 includes tworadial support ribs 12 and a plurality of first connectingribs 14 . Theradial support ribs 12 of the expanded venous stent are generally annular, which are used to fit with the inner wall of the blood vessel and play a role of supporting the blood vessel. Theradial support ribs 12 are bent into a wave shape, thereby forming a plurality of wave crests and wave troughs; for the convenience of description, the wave crests and wave troughs are collectively referred to asinflection points 16 . In the same radial support body 1, tworadial support ribs 12 are arranged symmetrically, that is, the crest of oneradial support rib 12 is arranged opposite to the trough of the otherradial support rib 12, and passes along the axis of the tapered venous stent. Connect to the extending first connectingrib 14 . The connection between the radial support body 1 and the first connectingrib 14 makes the radial support body 1 include a plurality of substantially hexagonal hollow holes.

为了将多个径向支撑体1连接形成一个整体，锥形静脉支架还设置了第二连接筋2。相邻的径向支撑体1相邻一侧的拐点16分别通过第二连接筋2连接，即，一个径向支撑体1右侧(以图2为参考)的拐点16与相邻的径向支撑体1左侧的拐点16通过第二连接筋2连接。In order to connect a plurality of radial supports 1 to form a whole, the conical venous stent is also provided with a second connectingrib 2 . Theinflection points 16 on the adjacent sides of the adjacent radial supports 1 are respectively connected by the second connectingribs 2 , that is, theinflection point 16 on the right side of one radial support 1 (with reference to FIG. 2 ) is connected to the adjacent radial support 1 . Theinflection point 16 on the left side of the support body 1 is connected by the second connectingrib 2 .

进一步，沿锥形静脉支架的锥度方向(即直径逐渐缩小的方向)，径向支撑体1的镂空孔数量依次递减，递减数量为1。此时，相邻的两个径向支撑体1，其用于与第二连接筋2连接的拐点16的数量也不同，镂空孔数量多的其拐点16也多，此时，镂空孔数量多的径向支撑体1的拐点16上均连接有第二连接筋2。由于拐点16数量不同，相邻的两个径向支撑体1的拐点16无法一一对应，此时，只需要将多出来一个第二连接筋2的另一端就近与相邻的径向支撑体1的拐点16连接即可。采用上述结构能够有效提高整个锥形静脉支架的整体抗折断性，提高其径向支撑力。Further, along the taper direction of the tapered venous stent (that is, the direction in which the diameter gradually decreases), the number of hollow holes in the radial support body 1 decreases sequentially, and the decreasing number is 1. At this time, the number ofinflection points 16 used to connect with the second connectingribs 2 of the two adjacent radial supports 1 is also different, and the number ofinflection points 16 with a large number of hollow holes is also large. At this time, the number of hollow holes is large. The second connectingribs 2 are connected to theinflection points 16 of the radial support body 1 . Due to the different number ofinflection points 16, theinflection points 16 of two adjacent radial supports 1 cannot be in one-to-one correspondence. In this case, it is only necessary to connect the other end of an extra second connectingrib 2 to the adjacent radial support body. Theinflection point 16 of 1 can be connected. By adopting the above structure, the overall fracture resistance of the entire conical venous stent can be effectively improved, and the radial support force thereof can be improved.

进一步，第二连接筋2的长度沿锥形支架的锥度方向呈比例递减。即管径较小的部分，其第二连接筋2的长度也较小。由于静脉血管中，管径较小的部位其可能是因为病变比较严重导致血管过于狭窄，因此其需要较大的径向支撑力；采用长度递减的第二连接筋2其能够使得膨胀后的锥形静脉支架中管径较小部位的整体刚度更大，为血管提供更大的支撑力。本实施例中，上述比例的数值为0.9；在其它实施例中，可以是0.8-0.9之间的任意数值，例如0.8。当上述数值过小时，第二连接筋2的长度变化幅度太大，其不利于提供均变化的径向支撑力；当上述数值过大时(例如0.95)，血管支架的整体柔顺性较差。Further, the length of the second connectingrib 2 decreases proportionally along the taper direction of the tapered bracket. That is, the length of the second connectingrib 2 is also smaller in the part with smaller pipe diameter. In the venous blood vessels, the parts with smaller diameters may be too narrow due to severe lesions, so they require a larger radial support force; the use of the second connectingrib 2 with decreasing length can make the expanded cone The overall stiffness of the smaller diameter part of the venous stent is greater, providing greater support for the blood vessel. In this embodiment, the value of the above ratio is 0.9; in other embodiments, it can be any value between 0.8-0.9, for example, 0.8. When the above value is too small, the length of the second connectingrib 2 varies too much, which is not conducive to providing uniform radial support force; when the above value is too large (for example, 0.95), the overall flexibility of the vascular stent is poor.

本实施例提供的锥形静脉支架，其有益效果如下：上述锥形静脉支架具有较强的抗折断性，其柔顺性好；径向支撑能力好，自膨胀能力强，有利于对静脉血管进行扩张。锥形静脉支架还可以通过匹配病变两端不同的静脉管径，最大程度契合静脉走形以减少不必要的静脉内膜刺激，实现延长支架通畅时间，恢复静脉回流并降低支架术后远期功能障碍事件发生率。The conical venous stent provided in this embodiment has the following beneficial effects: the above-mentioned conical venous stent has strong fracture resistance and good flexibility; good radial support ability and strong self-expansion ability expansion. The tapered venous stent can also match the different venous diameters at both ends of the lesion to fit the venous shape to the greatest extent to reduce unnecessary venous intimal stimulation, prolong stent patency, restore venous return and reduce long-term function after stenting. Obstacle event rate.

需要说明的是，本申请中，关于对形状结构的描述均是以血管支架膨胀之后的状态为参考进行描述的。另外，上述锥形静脉支架可以采用生物可降解材料或金属制成。It should be noted that, in this application, the description about the shape and structure is all described with reference to the state after the vascular stent is expanded. In addition, the above-mentioned conical vein stent can be made of biodegradable material or metal.

以上所述仅为本发明的优选实施方式而已，并不用于限制本发明，对于本领域的技术人员来说，本发明可以有各种更改和变化。凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A tapered venous stent, comprising:

the radial support bodies comprise two annular radial support ribs and a plurality of first connecting ribs; the radial support ribs are wavy and comprise a plurality of inflection points; the number of the inflection points is equal to that of the first connecting ribs;

the number of the inflection points of the two radial support ribs is equal, and the inflection points on one adjacent side of the two radial support ribs are respectively connected through the first connecting rib, so that the radial support body comprises a plurality of hexagonal hollow holes;

the inflection points of the adjacent sides of the adjacent radial support bodies are respectively connected through the second connecting ribs;

the radial dimension of the plurality of radial supports is gradually reduced along the taper direction of the tapered venous stent.

2. The tapered venous stent of claim 1 wherein the number of hollowed out holes of the radial struts decreases sequentially in the direction of taper.

3. The tapered venous stent of claim 2 wherein the difference in the number of the free holes of adjacent radial struts is 1.

4. The tapered venous stent of claim 1, wherein the length of the second connecting rib decreases proportionally along the direction of taper of the tapered venous stent.

5. The tapered venous stent of claim 4, wherein the ratio has a value of 0.8-0.9.