CN110652472A - METHODS OF DEEP OCEAN CONCENTRATE SKIN TREATMENT FORMULATIONS FOR IMPROVING THE APPEARANCE OF AGING - Google Patents

Abstract

Translated fromChinese

本发明公开了海洋深层浓缩物皮肤理疗配方用于改善皮肤样貌的方法；其步骤包括提供第一剂、第二剂与纤维膜，并施于患部表面，并搭配理疗仪进行施用。理疗仪施用的电流为0.1～0.8mA/cm²。

The present invention discloses a method for improving skin appearance by using a deep sea concentrate skin therapy formula; the steps include providing a first dose, a second dose and a fiber membrane, applying them to the affected part surface, and using a therapy device for application. The current applied by the therapy device is 0.1-0.8 mA/cm² .

Description

Translated fromChinese

海洋深层浓缩物皮肤理疗配方用于改善人体老化样貌的方法METHODS OF DEEP OCEAN CONCENTRATE SKIN TREATMENT FORMULATIONS FOR IMPROVING THE APPEARANCE OF AGING

【技术领域】【Technical field】

本发明涉及海洋深层浓缩物皮肤理疗配方用于改善皮肤样貌的方法；其步骤包括提供海洋深层浓缩物、皮肤用理疗配方与纤维膜，并施于患部表面，且特别有关于搭配使用理疗仪进行施用。The invention relates to a method for improving the appearance of the skin with a deep-sea concentrate skin physiotherapy formulation; the steps include providing the deep-sea concentrate, a skin physiotherapy formulation and a fiber membrane, and applying them to the surface of the affected part, and particularly relates to the use of a physiotherapy instrument in combination. Apply.

【背景技术】【Background technique】

海洋深层水(deep-sea water,DSW)是取自低于海平面200米以下的低温、洁净无污染的海水，其特性包含:(1)洁净性：深层海水与表层海水不同，深层海水不受人为污染的影响，表层海水在沉淀过程中，细菌会因化学酸化、沉淀、移流扩散等分解作用，且会随深度而逐渐减少。因深海无残存细菌所需的有机物质沉淀且不含硝酸体氮素的供给，细菌难以繁殖。因此，导致病变的各种有害细菌或病菌，在深层海水中的含量均极为稀少，仅为表层水的千分之一至万分之一。再者，残存在深层海水中的有机物，对微生物分解残渣有机物作用的抵抗性相当安定，这也是深层海水水质在微生物学或物理化学方面较为安定、无机且清净的原因。(2)低温性：由于太阳光线无法照到深层海水，所以水温较表层海水低，且温度没有相对明显的变化，终年维持低温稳定状态。(3)富无机营养盐：由于深层海水光线不足，生物无法进行光合作用，因此植物性浮游生物所需的必要营养盐－氮、磷、硅、硝酸等都无法消耗，大量累积在深层海水中。(4)熟成安定性：处于高压与大气隔絶的影响，使深层海水长年成份稳定。(5)富矿物质性：海洋中的矿物质主要来自岩层，经雨水冲刷至海洋，形成水溶性矿物质，均匀分布在海水中。Deep-sea water (DSW) is obtained from low-temperature, clean and pollution-free seawater below 200 meters above sea level. Influenced by man-made pollution, during the precipitation process of surface seawater, bacteria will be decomposed by chemical acidification, precipitation, migration and diffusion, and will gradually decrease with depth. Because there is no precipitation of organic matter required by residual bacteria in the deep sea and no supply of nitrate nitrogen, it is difficult for bacteria to multiply. Therefore, the content of various harmful bacteria or germs that cause lesions is extremely rare in deep seawater, only one thousandth to one ten thousandth of surface water. Furthermore, the organic matter remaining in the deep seawater has a relatively stable resistance to the action of microorganisms decomposing the residual organic matter, which is why the water quality of the deep seawater is relatively stable, inorganic and clean in terms of microbiology or physicochemistry. (2) Low temperature: Since the sun's rays cannot reach the deep seawater, the water temperature is lower than that of the surface seawater, and the temperature does not change significantly, maintaining a stable low temperature state all year round. (3) Rich inorganic nutrients: Due to the lack of light in the deep seawater, organisms cannot perform photosynthesis, so the necessary nutrients for plant plankton - nitrogen, phosphorus, silicon, nitric acid, etc. cannot be consumed, and a large amount of them accumulate in the deep seawater. . (4) Stability of maturation: Under the influence of high pressure and isolation from the atmosphere, the composition of deep seawater is stable for many years. (5) Mineral richness: The minerals in the ocean mainly come from rock formations and are washed into the ocean by rainwater to form water-soluble minerals, which are evenly distributed in the seawater.

近几年，海洋深层水已被广泛应用于食品加工业、农业、与药用。有研究文献指出海洋深层水能降低血脂肪、脂质氧化、血管硬化与高血压，同时也能减少血管管壁增生；虽然在异位性皮肤炎的研究上，也发现病患在饮用或浸泡深层海水后能改善皮肤发炎与过敏的症状、然而并未大规模应用在化妆品产业上。此外，饮用海洋深层水也被发现能用于改善白内障。并已有文献指出，在细胞实验中发现、海洋深层水可刺激胶原蛋白新生，使肌肤美白，抑制或治疗发炎的现象。In recent years, deep ocean water has been widely used in food processing industry, agriculture, and medicine. Some research literature points out that deep ocean water can reduce blood fat, lipid oxidation, vascular sclerosis and hypertension, and can also reduce vascular wall hyperplasia; although in the study of atopic dermatitis, it was also found that patients drinking or soaking Deep seawater can improve the symptoms of skin inflammation and allergies, but it has not been widely used in the cosmetics industry. In addition, drinking deep ocean water has also been found to improve cataracts. It has been pointed out in the literature that deep ocean water can stimulate collagen regeneration, whiten the skin, and inhibit or treat inflammation in cell experiments.

市售各类化妆品或保养品因属于大分子且海洋深层浓缩物具高表面张力，因此不易被皮肤吸收。再者，保养品和化妆品混合海洋深层浓缩液或海洋深层水放置一段时间后会变质。所以保养品和化妆品混合海洋深层浓缩液或海洋深层水后不宜放置太久，而本发明提供一种海洋深层浓缩物皮肤理疗配方施用在患部上的方法，可以解决上述问题，并使保养品与海洋深层浓缩物快速地穿透皮脂膜，达到真皮层，使患者的外观及样貌有所改善。Various types of cosmetics or skin care products on the market are not easily absorbed by the skin due to their macromolecules and the high surface tension of deep-ocean concentrates. Furthermore, skin care products and cosmetics mixed with deep-ocean concentrates or deep-ocean water can deteriorate over time. Therefore, skin care products and cosmetics should not be left for too long after mixing deep-ocean concentrate or deep-ocean water. The present invention provides a method for applying a deep-ocean concentrate skin physiotherapy formula to the affected area, which can solve the above problems and make skin care products and skin care products more compatible with The Deep Ocean Concentrate quickly penetrates the sebum membrane and reaches the dermis, improving the patient's appearance and appearance.

【发明内容】[Content of the invention]

有鉴于此，本发明提供一种海洋深层浓缩物皮肤理疗配方用于改善老化样貌的方法。且本发明的海洋深层浓缩物皮肤理疗配方的特征在于其具有立即微粒化皮肤用理疗配方、立即减少海洋深层浓缩物的高表面张力，解决皮肤不易吸收的问题以及海洋深层浓缩物的物质特性能，成为微粒化后的皮肤用理疗配方渗透的推动力(Driving Force)，并搭配理疗仪使用，可使皮肤理疗配方快速地进入穿透皮脂膜，达到真皮层，并达到减缓胶原蛋白流失、达到抗衰老的效果。In view of this, the present invention provides a method for improving the appearance of aging with a deep ocean concentrate skin treatment formulation. And the skin physiotherapy formulation of the deep ocean concentrate of the present invention is characterized in that it has the physiotherapy formulation for the skin to be micronized immediately, the high surface tension of the deep ocean concentrate is immediately reduced, the problem that the skin is not easily absorbed, and the material properties of the deep ocean concentrate are solved. , become the driving force for the penetration of the micronized skin physiotherapy formula, and used with the physiotherapy device, the skin physiotherapy formula can quickly penetrate the sebum membrane, reach the dermis, and slow down the loss of collagen. Anti-aging effect.

本发明提供一种海洋深层浓缩物皮肤理疗配方的使用方法，其步骤包括:(a)提供第一剂，其中所述第一剂是为海洋深层浓缩物；(b)提供第二剂，其中所述第二剂是为皮肤用理疗配方；(c)提供纤维膜，将所述纤维膜先浸润在所述第二剂中再浸润在所述第一剂中，形成浸润纤维膜；(d)将所述浸润纤维膜立即敷贴在患部表面上；(e)施用一理疗仪于所述浸润纤维膜上，所述理疗仪每平方厘米施用的电流为0.1mA～0.8mA，每平方厘米施用的时间为15～30秒；其中，通过所述步骤(e)使所述第一剂与所述第二剂快速地穿透皮脂膜达到真皮层，并达到刺激胶原蛋白增生。The present invention provides a method of using a deep ocean concentrate skin physiotherapy formulation, the steps of which include: (a) providing a first dose, wherein the first dose is a deep ocean concentrate; (b) providing a second dose, wherein The second agent is a physiotherapy formulation for skin; (c) providing a fibrous membrane, first infiltrating the fibrous membrane in the second agent and then infiltrating the first agent to form an infiltrating fibrous membrane; (d) ) Immediately apply the infiltrated fibrous membrane on the surface of the affected part; (e) apply a physiotherapy device on the infiltrated fibrous membrane, and the current applied by the physiotherapy device per square centimeter is 0.1 mA to 0.8 mA, and each square centimeter The application time is 15-30 seconds; wherein, through the step (e), the first agent and the second agent can quickly penetrate the sebum membrane to reach the dermis layer, and achieve the stimulation of collagen hyperplasia.

优选地，其中于所述浸润纤维膜中，所述第一剂的有效浓度至少大于或等于1.25(v/v)％。Preferably, the effective concentration of the first agent is at least greater than or equal to 1.25 (v/v)% in the infiltrated fiber membrane.

优选地，在步骤(d)中，所述浸润纤维膜在10分钟内施用在所述患部上。Preferably, in step (d), the infiltrated fibrous membrane is applied on the affected part within 10 minutes.

优选地，在步骤(e)中，在10分钟内施用所述理疗仪于所述浸润纤维膜上。Preferably, in step (e), the physiotherapy device is applied on the infiltrated fiber membrane within 10 minutes.

优选地，其中所述患部为脸部、手臂、腹部或腿部。Preferably, the affected part is the face, arm, abdomen or leg.

优选地，所述理疗仪施用的电流，因患部使用纤维膜大小及位置不同，为0.1mA～0.8mA/cm²，施作时间为患部贴膜15～30秒/cm²。Preferably, the current applied by the physiotherapy apparatus is 0.1 mA to 0.8 mA/cm² due to the size and position of the fibrous membrane used in the affected part, and the application time is 15 to 30 seconds/cm² of the affected part film.

优选地，其中所述第一剂的镁浓度为6500～110000mg/l、钠浓度为3800～30000mg/l、钾浓度为400～18000mg/l、钙浓度为100～500mg/l。硬度为80000～420000mg/l，盐度为380～430‰。所述第一剂每100g中含有1000～1500mg的钙、1400～2100mg镁、2000～4000mg的钠、1400～2100mg的钾、硫酸根＜6.5wt％，且比重为1.17～1.32g/cm³的海洋矿物质的溶液。优选地，所述第一剂取自海洋200m以下的水源；优选地，所述第一剂取自海洋500m以下的水源。优选地，所述第一剂为液体或粉体。Preferably, the magnesium concentration of the first dose is 6500-110000 mg/l, the sodium concentration is 3800-30000 mg/l, the potassium concentration is 400-18000 mg/l, and the calcium concentration is 100-500 mg/l. The hardness is 80000～420000mg/l, and the salinity is 380～430‰. The first dose contains 1000-1500 mg of calcium, 1400-2100 mg of magnesium, 2000-4000 mg of sodium, 1400-2100 mg of potassium, and sulfate <6.5 wt% per 100 g, and the specific gravity is 1.17-1.32 g/cm³ A solution of marine minerals. Preferably, the first dose is taken from a water source below 200m in the ocean; preferably, the first dose is taken from a water source below 500m in the sea. Preferably, the first agent is liquid or powder.

优选地，其中所述第二剂是为抗老、拉提、紧致、美白、保湿、医学或美容导入用品、促进胶原蛋白增生产品。优选地，所述第二剂为凝胶状。Preferably, wherein the second agent is anti-aging, lifting, firming, whitening, moisturizing, medical or cosmetic introduction products, and collagen-promoting products. Preferably, the second agent is in the form of a gel.

优选地，所述理疗仪是包含给电装置与传感器，所述给电装置包含外表面及内装；其中，所述给电装置的外表面包含:操作面板，其设置于所述理疗仪的侧面，藉以提供控制指令，调控所述给电装置所输出的直流电，所述直流电由不同强度与不同时间比例的正负电所组合；传感器连接孔，藉以外接所述传感器，所述传感器连接孔具有稳定电流侦测电路，电连控制电路以及所述传感器连接孔，用以放大刺激电流的电压；以及电源输入端，设置于所述理疗仪的另一侧面，藉以向所述给电装置提供电源，所述电源输入端具有复数安全电路，电连所述控制电路以及所述电源输入端，用以控制所述电源的不同电压；其中，所述给电装置的内装具有所述控制电路，电连所述操作面板取得所述控制指令以及所述电源输入端取得所述电源供应，并经由所述传感器连接孔输出所述直流电，包含:固定实测人体电路，用以控制所述直流电的不同强度；以及开关阀电路，经由所述控制指令选择，控制所述直流电的正负电；其中，所述传感器指以电线外接所述给电装置的所述传感器连接孔，其具有特定面积界面的放电端，使所述直流电经由所述传感器输出所述刺激电流。Preferably, the physical therapy device includes a power supply device and a sensor, and the power supply device includes an outer surface and an interior; wherein, the outer surface of the power supply device includes: an operation panel, which is arranged on the side of the physical therapy device , so as to provide control commands to regulate the direct current output by the power supply device, the direct current is composed of positive and negative electricity with different intensities and different time ratios; the sensor connection hole is used to connect the sensor, and the sensor connection hole has a A stable current detection circuit, which is electrically connected to the control circuit and the sensor connection hole, is used to amplify the voltage of the stimulation current; and a power input terminal, which is arranged on the other side of the physiotherapy apparatus, so as to provide power to the power supply device , the power supply input terminal has a plurality of safety circuits, which are electrically connected to the control circuit and the power supply input terminal to control different voltages of the power supply; wherein, the power supply device is equipped with the control circuit, which is electrically Connect the operation panel to obtain the control command and the power input terminal to obtain the power supply, and output the direct current through the sensor connection hole, including: fixing the actual measured human body circuit to control the different intensities of the direct current and an on-off valve circuit, selected by the control command, to control the positive and negative power of the direct current; wherein, the sensor refers to the sensor connection hole of the power supply device externally connected by a wire, which has a discharge with a specific area interface terminal, so that the direct current outputs the stimulation current through the sensor.

优选地，所述理疗仪施用的电流为2mA～25mA，优选地，根据纤维膜大小改变电流，每平方厘米施用电流0.1～0.8mA，施作时间为患部纤维膜15～30秒/cm²。Preferably, the current applied by the physiotherapy device is 2 mA to 25 mA. Preferably, the current is changed according to the size of the fibrous membrane, and the current is 0.1 to 0.8 mA per square centimeter, and the application time is 15 to 30 seconds/cm² of the fibrous membrane of the affected part.

较佳地，根据所述纤维膜的大小，所述第二剂的使用量为每平方厘米0.4克。Preferably, according to the size of the fiber membrane, the dosage of the second agent is 0.4 grams per square centimeter.

为达到上述及其它目的，以下对本发明的一或多个具体实施例进行说明。本发明的其它特征或优点以实施例详细描述。To achieve the above and other objects, one or more specific embodiments of the present invention are described below. Other features or advantages of the present invention are described in detail by way of examples.

【附图说明】【Description of drawings】

图1为人体脸部老化样貌变化示意图。Figure 1 is a schematic diagram of the changes in the aging appearance of the human face.

图2A为本发明的使用方法用于眼部的使用前的眼部示意图。FIG. 2A is a schematic view of the eye before using the method of use of the present invention for the eye.

图2B为本发明的使用方法用于眼部的使用后的眼部示意图，2B is a schematic diagram of the eye after the use method of the present invention is used for the eye,

图2C为本发明的使用方法用于眼部的使用后一天的眼部示意图，图2A-2C显示了本发明的使用方法用于眼部前后眼部黑眼圈、鱼尾纹的变化。2C is a schematic diagram of the eye one day after the use method of the present invention is applied to the eye, and FIGS. 2A-2C show the changes of dark circles and crow's feet before and after the use method of the present invention is applied to the eye.

图2D为本发明的使用方法用于眼部的使用前的眼部示意图。FIG. 2D is a schematic view of the eye before the use method of the present invention is applied to the eye.

图2E为本发明的使用方法用于眼部的使用后的眼部示意图。FIG. 2E is a schematic diagram of the eye after the use method of the present invention is applied to the eye.

图2F为本发明的使用方法用于眼部的使用后一天的眼部示意图，图2D-2F显示了本发明的使用方法用于眼部前后眼部的变化。FIG. 2F is a schematic diagram of the eye one day after the use method of the present invention is applied to the eye area, and FIGS. 2D-2F show the changes of the eye area before and after the use method of the present invention is applied to the eye area.

图3A为本发明的使用方法用于脸部的使用前的脸部示意图。FIG. 3A is a schematic diagram of the face before the use method of the present invention is applied to the face.

图3B为本发明的使用方法用于脸部的使用后第四天的脸部示意图。3B is a schematic diagram of the face on the fourth day after the use of the method of the present invention on the face.

图3C为本发明的使用方法用于脸部的使用后第五天的脸部示意图，图3A-3C显示了本发明的使用方法用于脸部前后脸部的法令纹及木偶纹的变化。3C is a schematic diagram of the face on the fifth day after using the method of the present invention on the face, and FIGS. 3A-3C show the changes of the nasolabial and puppet lines on the front and rear of the face using the method of the present invention.

图3D为本发明的使用方法用于脸部前的脸部示意图。FIG. 3D is a schematic diagram of the face before the method of use of the present invention is applied to the face.

图3E为本发明的使用方法用于脸部后的脸部示意图图3D-3E显示了本发明的使用方法用于脸部前后脸部的法令纹及木偶纹的变化FIG. 3E is a schematic diagram of the face after the method of use of the present invention is applied to the face. FIGS. 3D-3E show the changes of the nasolabial pattern and the puppet pattern of the face before and after the method of use of the present invention is applied to the face.

图4A为本发明的使用方法用于脸部前的脸部示意图。4A is a schematic diagram of the face before the method of use of the present invention is applied to the face.

图4B为本发明的使用方法用于脸部后的脸部示意图，图4A-4B显示了本发明的使用方法用于脸部前后颈部松弛(即双下巴)的变化。Fig. 4B is a schematic diagram of the face after the application method of the present invention is applied to the face, and Figs. 4A-4B show the changes of neck relaxation (ie double chin) before and after the application method of the present invention is applied to the face.

图5为理疗仪控制电路示意图。Figure 5 is a schematic diagram of the control circuit of the physiotherapy apparatus.

图6A为海洋深层浓缩物对于抑制基质金属蛋白酶-1的酵素活性效果。Figure 6A is the enzymatic effect of deep ocean concentrate on inhibiting matrix metalloproteinase-1.

图6B为海洋深层浓缩物对于抑制基质金属蛋白酶-3的酵素活性效果。Figure 6B shows the enzymatic effect of deep ocean concentrate on inhibiting matrix metalloproteinase-3.

图7为海洋深层浓缩物对于增加分泌胶原蛋白的效果。Figure 7 shows the effect of deep ocean concentrate on increasing collagen secretion.

【具体实施方式】【Detailed ways】

本发明提供一种海洋深层浓缩物皮肤理疗配方用于改善外观与样貌的方法。The present invention provides a method for improving the appearance and appearance of a deep ocean concentrate skin physiotherapy formulation.

本发明中所述的“海洋深层水”指取自海平面下200至1500米，优选为海平面下500至700米的海水，每100g溶(液/粉)中含有1000～1500mg的钙、1400～2100mg镁、2000～4000mg的钠、1400～2100mg的钾、硫酸根＜6.5wt％且比重为1.17-1.32g/cm³的海洋矿物质的溶液。The "deep ocean water" mentioned in the present invention refers to the sea water taken from 200 to 1500 meters below the sea level, preferably 500 to 700 meters below the sea level, and each 100 g of solution (liquid/powder) contains 1000 to 1500 mg of calcium, Solution of 1400-2100 mg magnesium, 2000-4000 mg sodium, 1400-2100 mg potassium, sulfate <6.5 wt% and specific gravity 1.17-1.32 g/^cm3 of marine minerals.

本发明中所述的“海洋深层浓缩物”指海洋深层水经浓缩程序后所产生的液体或粉体。此海洋深层浓缩(液/粉)浓缩程序使用纤维过滤系统、超过滤系统、海水逆渗透系统、低温真空蒸发浓缩系统及/或离心等步骤。The "deep-ocean concentrate" mentioned in the present invention refers to the liquid or powder produced by the concentration of deep-ocean water. This deep ocean concentration (liquid/powder) concentration procedure uses steps such as fiber filtration system, ultrafiltration system, seawater reverse osmosis system, low temperature vacuum evaporation concentration system and/or centrifugation.

海洋深层浓缩物的硬度为80000～420000mg/l、盐度为380～430‰、镁浓度为6500～110000mg/l及钠浓度为3800～30000mg/l。本发明的海洋深层浓缩物富含多种矿物质，包括，但不限于，钙(Ca)、钾(K)、铁(Fe)、锌(Zn)、钼(Mo)、锰(Mn)、锂(Li)、锶(Sr)、铜(Cu)、硅(Si)等微量元素。在一实施例中，海洋深层浓缩物的成分如表一所示，但由于检测单位未将完整的元素检测完成，所以本发明的海洋深层浓缩物不限于此。The hardness of the deep ocean concentrate is 80000-420000 mg/l, the salinity is 380-430‰, the magnesium concentration is 6500-110000 mg/l and the sodium concentration is 3800-30000 mg/l. The deep ocean concentrates of the present invention are rich in various minerals including, but not limited to, calcium (Ca), potassium (K), iron (Fe), zinc (Zn), molybdenum (Mo), manganese (Mn), Trace elements such as lithium (Li), strontium (Sr), copper (Cu), and silicon (Si). In one embodiment, the composition of the deep-ocean concentrate is shown in Table 1, but since the detection unit has not completed the complete element detection, the deep-ocean concentrate of the present invention is not limited to this.

表一、海洋深层浓缩物的成分Table 1. Composition of deep ocean concentrates

配方1Recipe 1配方3Recipe 3配方1Recipe 1配方3Recipe 3钾Potassium0.53％0.53%1.4％1.4%HCO₃HCO₃N/AN/AN/AN/A钙calcium13.9ppm13.9ppm8.92ppm8.92ppm碳酸盐carbonateN/AN/AN/AN/A钛titanium0.03ppm0.03ppmN.D.N.D.铝aluminumN.D.N.D.N.D.N.D.钒vanadium2.21ppm2.21ppm0.54ppm0.54ppm锑antimonyN.D.N.D.N.D.N.D.锰manganeseN.D.N.D.N.D.N.D.砷arsenic1.52ppm1.52ppm0.13ppm0.13ppm铁iron0.09ppm0.09ppm0.04ppm0.04ppm铍berylliumN.D.N.D.N.D.N.D.铜copper0.03ppm0.03ppm0.02ppm0.02ppm硼boron235.1ppm235.1ppm0.31ppm0.31ppm锌Zinc0.53ppm0.53ppmN.D.N.D.铬chromium0.30ppm0.30ppm0.14ppm0.14ppm溴bromineN.D.N.D.N.D.N.D.钴cobalt0.22ppm0.22ppm0.03ppm0.03ppm锶strontiumN.D.N.D.N.D.N.D.钼molybdenum0.59ppm0.59ppm0.29ppm0.29ppm铅leadN.D.N.D.N.D.N.D.镍nickel0.26ppm0.26ppm0.07ppm0.07ppm镉cadmiumN.D.N.D.N.D.N.D.汞HGN.D.N.D.N.D.N.D.镁magnesium9.1％9.1%4.6％4.6%钡bariumN.D.N.D.N.D.N.D.硒seleniumN.D.N.D.N.D.N.D.氟fluorineN.D.N.D.N.D.N.D.锂lithium29.74ppm29.74ppm9.3ppm9.3ppm碘iodine3.8ppm3.8ppm1.0ppm1.0ppm钠sodium0.53％0.53%10％10%SO₄SO₄N.D.N.D.N.D.N.D.

本发明中所述的“纤维膜”指超细长纤维面膜。The "fibrous membrane" referred to in the present invention refers to an ultra-slender fiber mask.

本发明中所述的“浸润纤维膜”指浸润在所述皮肤理疗配方与所述海洋深层浓缩物后的纤维膜，其是含有海洋深层浓缩物与皮肤理疗配方的混合物。The "impregnated fibrous membrane" in the present invention refers to the fibrous membrane after infiltration of the skin treatment formulation and the deep-sea concentrate, which is a mixture of the deep-sea concentrate and the skin treatment formula.

本发明中所述的“皮肤理疗配方”指一般凝胶态配方产品及美容相关院所使用于疗程的配方。例如，美白用品、保湿用品、除皱用品、伤口愈合用品、速愈疗程等改善肌肤外观的用品。The "skin physiotherapy formula" mentioned in the present invention refers to general gel-form formula products and formulas used for treatment in beauty-related institutions. For example, whitening products, moisturizing products, anti-wrinkle products, wound healing products, quick-healing treatments and other products that improve the appearance of the skin.

本发明的“海洋深层浓缩物与皮肤理疗配方的混合物”或“第一剂与第二剂的混合物”指纤维膜浸润于所述皮肤理疗配方与所述海洋深层浓缩物后，所述海洋深层浓缩物会混合于所述皮肤理疗配方中，即纤维膜中会含有混合海洋深层浓缩物与皮肤理疗配方的混合物体。The "mixture of deep ocean concentrate and skin treatment formulation" or "mixture of the first dose and the second dose" of the present invention refers to that after the fibrous membrane is infiltrated into the skin treatment formulation and the deep sea concentrate, the deep sea The concentrate will be mixed into the skin treatment formula, ie the fibrous membrane will contain a mixture of the mixed deep ocean concentrate and the skin treatment formula.

然而，海洋深层浓缩物混合至皮肤理疗配方内一段时间后，海洋深层浓缩物会导致皮肤理疗配方变质、不稳定及崩解。因此，本发明的纤维膜浸润于所述第二剂再浸润于所述第一剂后，敷贴在患部表面上，在完成浸润后10天内，优选为9天、8天、7天、6天、5天、4天、3天、2天、1天内使用完毕，最佳为12小时、6小时、3小时、2小时、1小时内。However, the deep ocean concentrate can cause the skin treatment formula to deteriorate, become unstable and disintegrate after a period of time when it is mixed into the skin treatment formula. Therefore, after the fibrous membrane of the present invention is infiltrated in the second agent and then infiltrated in the first agent, it is applied on the surface of the affected part within 10 days after the completion of infiltration, preferably 9 days, 8 days, 7 days, 6 days Use within 1 day, 5 days, 4 days, 3 days, 2 days, and 1 day, preferably within 12 hours, 6 hours, 3 hours, 2 hours, and 1 hour.

海洋深层浓缩物在混合至皮肤用理疗配方后，仅经过10天，皮肤用理疗配方会明显变质。此外，海洋深层浓缩物会使皮肤用理疗配方产生不明的沉淀物及浮游物，显示海洋深层浓缩物若是混合至皮肤用理疗配方内一段时间，其离子会与成分产生化学变化，降低原有皮肤用理疗配方对肌肤的效果，甚至产生可能有害肌肤的衍生物。After the Deep Ocean Concentrate is mixed into the dermatological formula, the dermatological formula will deteriorate visibly after only 10 days. In addition, deep-ocean concentrates will cause unidentified sediments and floats in skin treatment formulations, indicating that if deep-ocean concentrates are mixed into skin treatment formulas for a period of time, their ions will chemically change with the ingredients, reducing the original skin. The effects of physiotherapy formulations on the skin, even with derivatives that may be harmful to the skin.

纤维膜浸润的方式并无特别限制，可使用一般的方法，例如，将纤维膜浸润在装有皮肤理疗配方的保鲜膜袋里，再将海洋深层浓缩物加入所述保鲜膜袋里，使纤维膜浸润到海洋深层浓缩物中。纤维膜浸润在皮肤理疗配方中浸润的时间并无特限制，但因为在纤维膜浸润到海洋深层浓缩物中后必须尽快使用以避免皮肤用理疗配方质量恶化，所以纤维膜浸润到海洋深层浓缩物中的时间不宜过长，通常为15分钟内，优选为14、13、12、11、10、9、8、7、6、5、4、3分钟内，最优选为10分钟内。浸润纤维膜放置的时间也不宜过长，通常为15分钟内敷贴在患部表面上，优选为14、13、12、11、10、9、8、7、6、5、4、3分钟内，最优选为10分钟内。在浸润纤维膜敷贴在患部表面后，也需要尽快施用理疗仪于浸润纤维膜上，通常为15分钟内将理疗仪施于浸润纤维膜上，优选为14、13、12、11、10、9、8、7、6、5、4、3分钟内，最优选为10分钟内。The method of infiltrating the fibrous membrane is not particularly limited, and general methods can be used, for example, dipping the fibrous membrane in a plastic wrap bag containing a skin physiotherapy formula, and then adding the deep-sea concentrate into the plastic wrap bag to make the fibers Membranes soak into deep ocean concentrates. There is no specific limit to the time of infiltration of the fibrous membrane into the skin treatment formulation, but because the fibrous membrane is infiltrated into the deep ocean concentrate, it must be used as soon as possible to avoid deterioration of the quality of the skin treatment formula, so the fibrous membrane is infiltrated into the deep ocean concentrate The time should not be too long, usually within 15 minutes, preferably within 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, 4, and 3 minutes, and most preferably within 10 minutes. The soaking fibrous membrane should not be placed for too long, usually within 15 minutes, and preferably within 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, 4, and 3 minutes. , most preferably within 10 minutes. After the infiltrated fibrous membrane is applied on the surface of the affected part, it is also necessary to apply the physiotherapy device on the infiltrated fibrous membrane as soon as possible. Usually, the physiotherapy device is applied to the infiltrated fibrous membrane within 15 minutes, preferably 14, 13, 12, 11, 10, Within 9, 8, 7, 6, 5, 4, 3 minutes, most preferably within 10 minutes.

如上所述，所述浸润纤维膜必须尽快敷在患部上，并尽快使用理疗仪导入，以避免皮肤用理疗配方的质量变化。As mentioned above, the infiltrated fibrous membrane must be applied to the affected part as soon as possible, and introduced using a physiotherapy apparatus as soon as possible, so as to avoid the quality change of the skin physiotherapy formula.

在纤维膜浸润到皮肤用理疗配方与海洋深层浓缩物后，所述海洋深层浓缩物会与所述皮肤理疗配方相混合，并可马上产生相转移，使保养品的分子变小，并搭配理疗仪使用让海洋深层浓缩物与皮肤理疗配方的混合物容易穿透皮脂膜，到达真皮层。After the fibrous membrane is infiltrated into the skin treatment formula and the deep ocean concentrate, the deep ocean concentrate is mixed with the skin treatment formula, and a phase transfer can occur immediately, so that the molecules of the skin care products are reduced and combined with the treatment The use of the instrument allows the blend of Deep Ocean Concentrate and Skin Therapy Formula to easily penetrate the sebum membrane and reach the dermis.

本实施例的使用方法根据纤维膜尺寸，使用每平方厘米0.4克的皮肤理疗配方浸润纤维膜，再使用每平方厘米0.4克的海洋深层浓缩物浸润纤维膜。并在浸润纤维膜的表面施用理疗仪，理疗仪每平方厘米施用的电流为0.1mA～0.8mA，每平方厘米施用的时间为15～30秒。The method of use of this example is based on the size of the fibrous membrane by infiltrating the fibrous membrane with 0.4 grams per square centimeter of the skin treatment formula, and then infiltrating the fibrous membrane with 0.4 grams per square centimeter of deep ocean concentrate. A physical therapy device is applied on the surface of the infiltrated fiber membrane. The current applied by the physical therapy device per square centimeter is 0.1 mA to 0.8 mA, and the application time per square centimeter is 15 to 30 seconds.

实施例1.56人的脸部测试结果Example 1.56 Face test results of people

测试对象为20-85岁，想改善脸部外貌者，女37人，男19人，测试者年龄请参阅表一。The test subjects are 20-85 years old, who want to improve their facial appearance. There are 37 females and 19 males. Please refer to Table 1 for the age of the testers.

表一、测试者年龄Table 1. Age of testers

年龄(岁)age)比例Proportion20-2920-297％7%30-3930-3920％20%40-4940-4931％31%50-5950-5920％20%60-6960-6920％20%70-7970-790％0%80以上80 or more2％2%

实施方式:将纤维膜放入装有皮肤用理疗配方的保鲜袋中，再将海洋深层浓缩物倒入上述的保鲜膜中，使纤维膜先浸润在皮肤用理疗配方中再浸润在海洋深层浓缩物中，得到浸润纤维膜。此时所述浸润纤维膜含有海洋深层浓缩物与皮肤理疗配方的混合物，其中所述海洋深层浓缩物的有效浓度至少大于或等于1.25(v/v)％。再将浸润纤维膜取出后立即敷贴在脸部表面上，再使用理疗仪于所述浸润纤维膜上，所述理疗仪施用的电流为根据纤维膜大小改变电流，每平方厘米施用电流0.1～0.8mA，施作时间为患部纤维膜15～30秒/cm²。Embodiment: put the fibrous membrane into the fresh-keeping bag that is housed with skin physiotherapy formula, then pour the deep-sea concentrate into the above-mentioned fresh-keeping film, make the fibrous membrane first infiltrate in the skin physiotherapy formula and then infiltrate the deep-ocean concentration In this case, an infiltrated fibrous membrane was obtained. The impregnated fibrous membrane now contains a mixture of deep ocean concentrate and a skin treatment formulation, wherein the effective concentration of the deep ocean concentrate is at least greater than or equal to 1.25 (v/v) %. The infiltrated fibrous membrane is taken out and immediately applied on the surface of the face, and then a physiotherapy device is used on the infiltrated fibrous membrane. The current applied by the physiotherapy device is to change the current according to the size of the fibrous membrane, and the current is applied per square centimeter of 0.1~ 0.8 mA, and the application time was 15 to 30 seconds/cm² for the fibrous membrane of the affected part.

其结果请参阅表二、表三以及图2～4。其中在实施后，改善了脸部细纹，以及改善了现有技术需要以侵入性治疗才能改善的「眼袋、眼尾下垂、鱼尾纹、眼皮下垂、眉心纹、法令纹、木偶纹、下颚线条、双下巴、颈纹、黑眼圈、痘疤」等样貌问题。The results are shown in Table 2, Table 3 and Figures 2-4. Among them, after the implementation, the fine lines on the face are improved, and the "eye bags, drooping eyes, crow's feet, drooping eyelids, eyebrow lines, nasolabial lines, puppet lines, chin lines, Double chin, neck lines, dark circles, acne scars and other appearance problems.

图2A为使用本发明方法前的眼部，图2B为使用本发明方法后的眼部变化，图2C为使用本发明方法后一天的眼部变化。在图2B中，眼周细纹、眼袋、眼尾下垂、鱼尾纹、眼皮下垂、眉心纹皆已经有改善。在图2C中，眼周细纹、眼袋、眼尾下垂、鱼尾纹、眼皮下垂、眉心纹有了更进一步的改善。Figure 2A shows the eye before using the method of the present invention, Figure 2B shows the change of the eye after using the method of the present invention, and Figure 2C shows the change of the eye one day after using the method of the present invention. In Fig. 2B, fine lines around the eyes, bags under the eyes, drooping eyes, crow's feet, drooping eyelids, and frown lines have all been improved. In Figure 2C, the fine lines around the eyes, bags under the eyes, drooping eyes, crow's feet, drooping eyelids, and frown lines were further improved.

图2D为使用本发明方法前的眼部，图2E为使用本发明方法后的眼部变化，图2F为使用本发明方法后一天的眼部变化。图2E中，眼周细纹、眼袋、眼尾下垂、鱼尾纹、眼皮下垂、眉心纹皆已经有改善。图2F中，眼周细纹、眼袋、眼尾下垂、鱼尾纹、眼皮下垂、眉心纹有了更进一步的改善。Figure 2D shows the eye before using the method of the present invention, Figure 2E shows the change of the eye after using the method of the present invention, and Figure 2F shows the change of the eye one day after using the method of the present invention. In Figure 2E, the fine lines around the eyes, bags under the eyes, drooping eyes, crow's feet, drooping eyelids, and frown lines have all been improved. In Figure 2F, the fine lines around the eyes, bags under the eyes, drooping eyes, crow's feet, drooping eyelids, and frown lines were further improved.

图3A-3C显示本发明的使用方法用于整体脸部的使用前后的比较图，显示了脸整体的变化。图3A为使用前，图3B为使用后第四天，图3C为使用后第五天。在图3B中，细纹、眼袋、眼尾下垂、鱼尾纹、眼皮下垂、眉心纹、法令纹、木偶纹、下颚线条、双下巴、颈纹、黑眼圈皆已经有改善。在图3C中，眼袋、眼尾下垂、下颚线条、双下巴更是有明显的进一步改善，脸颊两侧有明显拉提的效果。3A-3C show the comparison diagrams before and after use of the method of use of the present invention for the whole face, showing the changes of the whole face. FIG. 3A is before use, FIG. 3B is the fourth day after use, and FIG. 3C is the fifth day after use. In Figure 3B, fine lines, bags under the eyes, drooping under the eyes, crow's feet, drooping eyelids, eyebrow lines, nasolabial lines, puppet lines, jawline, double chin, neck lines, and dark circles have all been improved. In Figure 3C, eye bags, drooping eyes, jawline, and double chin were further improved, and both sides of the cheeks were significantly lifted.

图3D、3E显示本发明的使用方法用于脸部的使用前后的比较图，显示了脸整体的变化。图3D为使用前，图3E为使用后。在图3E中，细纹、眼袋、眼尾下垂、鱼尾纹、眼皮下垂、眉心纹、法令纹、木偶纹、下颚线条、双下巴、颈纹、黑眼圈，尤其是下颚线条，脸颊两侧有明显拉提的效果。3D and 3E show the comparison diagrams before and after the use method of the present invention is applied to the face, and show the overall change of the face. Figure 3D is before use, and Figure 3E is after use. In Fig. 3E, fine lines, bags under the eyes, drooping eyes, crow's feet, drooping eyelids, brow lines, nasolabial lines, puppet lines, chin line, double chin, neck lines, dark circles, especially the chin line, are obvious on both sides of the cheeks Lifting effect.

图4A-4B显示本发明的使用方法用于脸部的使用前后比较图，显示了颈部松弛(即双下巴)的变化。图4A为使用前，图4B为使用后。在图4B中，颈部松弛有明显改善，有明显下颚拉提的效果。Figures 4A-4B show a before-and-after comparison of the method of use of the present invention on the face, showing changes in neck laxity (ie, double chin). Figure 4A is before use, and Figure 4B is after use. In Figure 4B, neck laxity was significantly improved, and there was a significant jaw-lifting effect.

表二、56人脸部测试结果Table 2. 56 face test results

表三、56人脸部测试结果Table 3. Face test results of 56 people

实施例2.理疗仪Example 2. Physiotherapy Apparatus

本发明的使用方法配合理疗仪使用，理疗仪可使用一般市售的理疗仪，优选地，请参考图5理疗仪的控制电路示意图，理疗仪包含给电装置与传感器，所述给电装置包含外表面及内装；其中，所述给电装置的外表面包含:操作面板，其设置在所述理疗仪的侧面，藉以提供控制指令，调控所述给电装置所输出的直流电，所述直流电由不同强度与不同时间比例的正负电所组合；传感器连接孔，藉以外接所述传感器，所述传感器连接孔更具有稳定电流侦测电路127，电连控制电路以及所述传感器连接孔，用以放大刺激电流的电压；以及电源输入端，设置在所述理疗仪另一侧面，藉以向所述给电装置提供电源，所述电源输入端更具有复数安全电路125，电连所述控制电路以及所述电源输入端，用以控制所述电源的不同电压；其中，所述给电装置的内装具有所述控制电路，电连所述操作面板取得所述控制指令以及所述电源输入端取得所述电源供应，并经由所述传感器连接孔输出所述直流电，包含:固定实测人体电路126，用以控制所述直流电的不同强度；以及开关阀电路，经由所述控制指令选择，控制所述直流电的正负电；其中，所述传感器指以电线外接所述给电装置的所述传感器连接孔，其具有特定面积界面的放电端，使所述直流电经由所述传感器输出所述刺激电流。The method of use of the present invention is used with a physiotherapy apparatus, and the physiotherapy apparatus can be a commercially available physiotherapy apparatus. Preferably, please refer to the schematic diagram of the control circuit of the physiotherapy apparatus in FIG. 5. The physiotherapy apparatus includes a power supply device and a sensor, and the power supply device includes Outer surface and interior; wherein, the outer surface of the power supply device includes: an operation panel, which is arranged on the side of the physiotherapy apparatus, so as to provide a control command to regulate the direct current output by the power supply device, and the direct current is controlled by the power supply device. A combination of positive and negative electricity with different intensities and different time ratios; a sensor connection hole for external connection of the sensor, the sensor connection hole further has a stablecurrent detection circuit 127, an electrical connection control circuit and the sensor connection hole for amplifying the voltage of the stimulation current; and a power input end, arranged on the other side of the physiotherapy apparatus, so as to provide power to the power supply device, and the power input end further has a plurality ofsafety circuits 125, which are electrically connected to the control circuit and The power input terminal is used to control different voltages of the power supply; wherein, the power supply device is equipped with the control circuit, which is electrically connected to the operation panel to obtain the control command and the power input terminal to obtain the information. Described power supply, and output described direct current via described sensor connection hole, comprise: fix actual measurementhuman body circuit 126, in order to control the different intensity of described direct current; And switch valve circuit, selects through described control instruction, controls described direct current The sensor refers to the connection hole of the sensor connected to the power supply device with a wire, which has a discharge end with a specific area interface, so that the direct current can output the stimulation current through the sensor.

实施例3.抑制胶原蛋白流失Example 3. Inhibition of collagen loss

请参考图6A、图6B、表三以及表四，本发明委托工研院利用体外试管实验研究海洋深层浓缩物抑制基质金属蛋白酶-1(Matrix Metalloproteinase-1,MMP-1)及基质金属蛋白酶-3(Matrix Metalloproteinase-3,MMP-3)的效能。基质金属蛋白酶-1和基质金属蛋白酶-3是通称的胶原蛋白分解酶其中的两种，为调节光老化重要因子，纤维母细胞受阳光的紫外线曝晒会引起基质金属蛋白酶大量表现，进而降解细胞外基质(Extracellularmatrix,ECM)，也就是说MMP-1和MMP-3负责真皮组织中胶原蛋白的降解流失。通过此实验证实海洋深层浓缩物具有抑制胶原蛋白流失的功能，NNGH(N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid)为基质金属蛋白酶的失活药物(MMP失活药物)，由图6A、6B实验数据可得知，与NNGH抑制率相比(VS.NNGH)，0.5％浓度的海洋深层浓缩物可相对地抑制4.92％的基质金属蛋白酶-1活性以及抑制2.18％的基质金属蛋白酶-3活性。1％浓度的海洋深层浓缩物可抑15.13％的基质金属蛋白酶-1的活性以及抑制8.12％的基质金属蛋白酶-3活性。2％浓度的海洋深层浓缩物可抑制高达23.93％的基质金属蛋白酶-1活性以及抑制27.71％的基质金属蛋白酶-3活性。本实验说明海洋深层浓缩物可有效抑制基质金属蛋白酶-1和基质金属蛋白酶-3的酵素活性，与NNGH抑制率相比，抑制基质金属蛋白酶-1和基质金属蛋白酶-3活性的效果高达50％。表示海洋深层浓缩物具有抑制胶原蛋白流失的效能，促使肌肤细胞展现较优良健康状态，有利于所有针对肌肤细胞有效的成分加成效果。Please refer to Figure 6A, Figure 6B, Table 3 and Table 4. The present invention entrusts ITRI to use in vitro test tube experiments to study the inhibition of matrix metalloproteinase-1 (MMP-1) and matrix metalloproteinase-1 (MMP-1) and matrix metalloproteinase- 3 (Matrix Metalloproteinase-3, MMP-3) efficacy. Matrix metalloproteinase-1 and matrix metalloproteinase-3 are two of the commonly known collagen-degrading enzymes. In order to regulate the important factors of photoaging, the exposure of fibroblasts to the ultraviolet rays of the sun will cause a large number of matrix metalloproteinases to degrade extracellular matrix metalloproteinases. Matrix (Extracellular matrix, ECM), that is to say MMP-1 and MMP-3 are responsible for the degradation and loss of collagen in dermal tissue. Through this experiment, it was confirmed that the deep ocean concentrate has the function of inhibiting the loss of collagen. NNGH (N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid) is an inactivating drug of matrix metalloproteinase (MMP inactivating drug). The experimental data of 6A and 6B showed that compared with the inhibition rate of NNGH (VS.NNGH), 0.5% concentration of deep ocean concentrate can relatively inhibit the activity of MMP-1 by 4.92% and inhibit the activity of MMP-1 by 2.18%. -3 Active. 1% concentration of deep-ocean concentrate can inhibit the activity of MMP-1 by 15.13% and the activity of MMP-3 by 8.12%. The 2% concentration of deep ocean concentrate can inhibit up to 23.93% of MMP-1 activity and 27.71% of MMP-3 activity. This experiment shows that the deep ocean concentrate can effectively inhibit the enzymatic activities of MMP-1 and MMP-3. Compared with the inhibition rate of NNGH, the effect of inhibiting the activities of MMP-1 and MMP-3 is as high as 50%. . It means that the deep ocean concentrate has the effect of inhibiting the loss of collagen, and promotes the skin cells to show a better health state, which is beneficial to all the ingredients that are effective against the skin cells.

表四、抑制基质金属蛋白酶-1Table 4. Inhibition of matrix metalloproteinase-1

表五、抑制基质金属蛋白酶-3Table 5. Inhibition of matrix metalloproteinase-3

实施例4.增加胶原蛋白分泌Example 4. Increase Collagen Secretion

请参考图7，其中n值为8，长条图的平均标准差为*p<0.05，本实验以0-1％浓度的海洋深层浓缩物配搭维生素C复方，显示不同浓度的海洋深层浓缩物所分泌胶原蛋白的量。Please refer to Figure 7, where the value of n is 8, and the mean standard deviation of the bar graph is *p<0.05. In this experiment, 0-1% concentration of deep-ocean concentrate is matched with vitamin C compound, showing different concentrations of deep-ocean concentrate The amount of collagen secreted.

实施例5.电子状态Example 5. Electronic state

皮肤护理配方与海洋深层浓缩物混和后，产生微粒胞体表面电极及其电荷(图未示)，根据其比例设计直流电正电流及负电流施用的时间比例。After mixing the skin care formulation with the deep ocean concentrate, the microparticle cell surface electrodes and their charges (not shown) are generated, and the time ratio of the direct current positive current and the negative current application is designed according to their ratio.

发明所揭露的所有特征应可以任何结合方式实现。本发明所揭露的每一特征应可以相同、均等或相似目的的取代物所取代。因此，除非有明确的指定，否则所揭露的每一个特征仅仅只是均等物或相似特征的一个种类的一实施例。All features disclosed in the invention should be implemented in any combination. Each feature disclosed herein may be replaced by a substitute of the same, equivalent or similar purpose. Thus, unless expressly stated otherwise, each feature disclosed is only one embodiment of a class of equivalent or similar features.

【符号说明】【Symbol Description】

125 安全电路125 Safety circuits

126 固定实测人体电路126 Fixed measured human body circuit

127 稳定电流侦测电路127 Stable current detection circuit

Claims (11)

Translated fromChinese

1.一种海洋深层浓缩物皮肤理疗配方的使用方法，其特征在于，包括以下步骤:1. a using method of deep ocean concentrate skin physiotherapy formula, is characterized in that, comprises the following steps:(a)提供第一剂，所述第一剂为海洋深层浓缩物；(a) providing a first dose, the first dose being a deep ocean concentrate;(b)提供第二剂，所述第二剂为皮肤用理疗配方；(b) providing a second dose, the second dose being a dermatological formulation;(c)提供纤维膜，将所述纤维膜先浸润于所述第二剂再浸润于所述第一剂，形成浸润纤维膜；(c) providing a fibrous membrane, first infiltrating the fibrous membrane in the second agent and then infiltrating the first agent to form an infiltrating fibrous membrane;(d)将所述浸润纤维膜立即敷贴在患部表面上；(d) immediately applying the infiltrated fibrous membrane on the surface of the affected part;(e)施用理疗仪于所述浸润纤维膜上，所述理疗仪每平方厘米施用的电流为0.1mA～0.8mA，每平方厘米施用的时间为15～30秒；(e) applying a physical therapy device on the infiltrated fiber membrane, the current applied by the physical therapy device per square centimeter is 0.1 mA to 0.8 mA, and the application time per square centimeter is 15 to 30 seconds;其中，通过所述步骤(e)使所述第一剂与所述第二剂快速地穿透皮脂膜达到真皮层，并达到刺激胶原蛋白增生。Wherein, through the step (e), the first agent and the second agent can quickly penetrate the sebum membrane to reach the dermis layer, so as to stimulate the proliferation of collagen.2.根据权利要求1所述的使用方法，其特征在于：2. using method according to claim 1, is characterized in that:其中，根据所述纤维膜的大小，所述第二剂的使用量为每平方厘米0.4克。Wherein, according to the size of the fiber membrane, the usage amount of the second agent is 0.4 grams per square centimeter.3.根据权利要求1所述的使用方法，其特征在于：3. using method according to claim 1, is characterized in that:其中，在所述浸润纤维膜中，所述第一剂的有效浓度大于或等于1.25(v/v)％。Wherein, in the soaked fiber membrane, the effective concentration of the first agent is greater than or equal to 1.25 (v/v)%.4.根据权利要求1所述的使用方法，其特征在于：4. using method according to claim 1, is characterized in that:其中，在所述步骤(d)中，所述浸润纤维膜贴在10分钟内敷贴在所述患部表面。Wherein, in the step (d), the infiltrated fiber membrane sticker is applied on the surface of the affected part within 10 minutes.5.根据权利要求1所述的使用方法，其特征在于：5. using method according to claim 1, is characterized in that:其中，在所述步骤(e)中，在10分钟内施用所述理疗仪于所述浸润纤维膜上。Wherein, in the step (e), the physiotherapy device is applied on the infiltrated fiber membrane within 10 minutes.6.根据权利要求1所述的使用方法，其特征在于：6. using method according to claim 1, is characterized in that:其中，所述第一剂的镁浓度为6500～110000mg/l。Wherein, the magnesium concentration of the first dose is 6500-110000 mg/l.7.根据权利要求1所述的使用方法，其特征在于：7. using method according to claim 1, is characterized in that:其中，所述第一剂的钠浓度为3800～30000mg/l、钾浓度为400～18000mg/l、钙浓度为100～500mg/l。Wherein, the sodium concentration of the first dose is 3800-30000 mg/l, the potassium concentration is 400-18000 mg/l, and the calcium concentration is 100-500 mg/l.8.根据权利要求1所述的使用方法，其特征在于：8. using method according to claim 1, is characterized in that:其中，所述第一剂的硬度为80000～420000mg/l，盐度为380～430‰。Wherein, the hardness of the first agent is 80,000-420,000 mg/l, and the salinity is 380-430‰.9.根据权利要求1所述的使用方法，其特征在于：9. using method according to claim 1, is characterized in that:其中，所述第一剂每100g中含有1000～1500mg的钙、1400～2100mg镁、2000～4000mg的钠、1400～2100mg的钾、硫酸根＜6.5wt％，且比重为1.17～1.32g/cm³的海洋矿物质的溶液。Wherein, each 100g of the first dose contains 1000-1500mg of calcium, 1400-2100mg of magnesium, 2000-4000mg of sodium, 1400-2100mg of potassium, sulfate <6.5wt%, and the specific gravity is 1.17-1.32g/cm³ solutions of marine minerals.10.根据权利要求1所述的使用方法，其特征在于：10. using method according to claim 1, is characterized in that:其中，所述第二剂为美白用品、保湿用品、除皱用品、伤口愈合用品、医学或美容导入用品、促进胶原蛋白增生产品。Wherein, the second agent is whitening supplies, moisturizing supplies, wrinkle-removing supplies, wound healing supplies, medical or cosmetic introduction supplies, and collagen-promoting products.11.根据权利要求1所述的使用方法，其特征在于：11. using method according to claim 1, is characterized in that:其中，所述理疗仪包含给电装置与传感器，所述给电装置包含外表面及内装，Wherein, the physiotherapy apparatus includes a power supply device and a sensor, and the power supply device includes an outer surface and an interior,所述给电装置的所述外表面包含:The outer surface of the power delivery device includes:操作面板，其设置在所述理疗仪的侧面，藉以提供控制指令，调控所述给电装置所输出的直流电，所述直流电由不同强度与不同时间比例的正负电所组合；an operation panel, which is arranged on the side of the physiotherapy apparatus, so as to provide control instructions to regulate the direct current output by the power supply device, and the direct current is composed of positive and negative electricity with different intensities and different time ratios;传感器连接孔，用于外接所述传感器，所述传感器连接孔具有稳定电流侦测电路，所述稳定电流侦测电路电连控制电路以及所述传感器连接孔，用以放大刺激电流的电压；以及a sensor connection hole for external connection of the sensor, the sensor connection hole has a stable current detection circuit, and the stable current detection circuit is electrically connected to the control circuit and the sensor connection hole for amplifying the voltage of the stimulation current; and电源输入端，设置在所述理疗仪的另一侧面，藉以向所述给电装置提供电源，所述电源输入端具有复数安全电路，电连所述控制电路以及所述电源输入端，用以控制所述电源的不同电压，The power input terminal is arranged on the other side of the physiotherapy apparatus, so as to provide power to the power supply device, the power input terminal has a plurality of safety circuits, and is electrically connected to the control circuit and the power input terminal for control the different voltages of the power supply,其中，所述给电装置的所述内装具有所述控制电路，所述控制电路电连所述操作面板取得所述控制指令以及所述电源输入端取得所述电源的供应，并经由所述传感器连接孔输出所述直流电，Wherein, the built-in power supply device has the control circuit, and the control circuit is electrically connected to the operation panel to obtain the control command and the power input terminal to obtain the power supply, and through the sensor The connection hole outputs the direct current,所述控制电路包含:The control circuit includes:固定实测人体电路，用以控制所述直流电的不同强度；以及Fixing measured human body circuits for controlling different intensities of said direct current; and开关阀电路，经由所述控制指令选择，控制所述直流电的正负电，所述传感器以电线外接所述给电装置的所述传感器连接孔，其具有特定面积界面的放电端，使所述直流电经由所述传感器输出所述刺激电流。The switch valve circuit is selected by the control command to control the positive and negative power of the direct current, the sensor is connected to the sensor connection hole of the power supply device with a wire, and has a discharge end with a specific area interface, so that the The direct current outputs the stimulation current via the sensor.

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