技术领域technical field
本申请涉及人体健康领域，特别涉及一种用于检测血糖的方法及装置。The present application relates to the field of human health, in particular to a method and device for detecting blood sugar.
背景技术Background technique
糖尿病是一种以高血糖为特征的慢性疾病，因人体内胰岛素分泌不足或胰岛素作用受损而引起，并且主要表现为血糖浓度高于正常水平，从而导致人体的代谢紊乱。长期处于高血糖状态下会导致视觉障碍、心血管疾病、肾功能衰竭等问题，此外，还会增加心脏病、中风等疾病的患病风险。因此，它是一种严重威胁人类健康的疾病。Diabetes is a chronic disease characterized by high blood sugar, which is caused by insufficient insulin secretion or impaired insulin action in the human body, and is mainly manifested as a higher blood sugar concentration than normal, which leads to metabolic disorders in the human body. Long-term high blood sugar can lead to problems such as visual impairment, cardiovascular disease, and renal failure. In addition, it can also increase the risk of heart disease, stroke, and other diseases. Therefore, it is a disease that seriously threatens human health.
目前常见的血糖检测方法主要分为有创和微创检测两种。有创检测多用于医院，即，从患者体内抽取血液样本，使用大型的离心机分离出血清，然后通过生物化学的方法得到血糖浓度值。有创血糖检测的优点在于能够获得较为精确的血糖浓度值，然而，这种方法每次都要抽取患者血液样本，对操作人员有一定的要求，每次检测需要在医院中进行，测量成本较高，并且血液样本需要较长的检测时间，因而不能达到实时检测的目的，这些都给糖尿病患者带来不便。微创检测的测量方法有比色法或电化学法，即，从指间或者其他人体组织中采集血液样本，然后由血糖检测仪上的试纸条通过吸宏作用将血液吸入，以测量血糖浓度。微创检测的优点在于患者可自己进行操作，在日常生活中方便实用，但是也正因为如此，如果在采集过程中操作不当或消毒不完善，则有可能导致患者被传染其他疾病或者被感染，采用这种方法进行长期的血糖测量也会给患者带来一定的风险，并且每次测量均需要采血并消耗一次性试纸，手续复杂，这些问题也限制了患者进行检测的次数，从而影响了血糖监控的整体效果。The current common blood glucose testing methods are mainly divided into two types: invasive and minimally invasive. Invasive testing is mostly used in hospitals, that is, blood samples are drawn from patients, serum is separated using a large centrifuge, and blood glucose concentration values are obtained by biochemical methods. The advantage of invasive blood glucose detection is that it can obtain more accurate blood glucose concentration values. However, this method requires blood samples from patients every time, which has certain requirements for operators. Each detection needs to be carried out in a hospital, and the measurement cost is relatively high. High, and the blood sample requires a long detection time, so the purpose of real-time detection cannot be achieved, which brings inconvenience to diabetic patients. The measurement methods of minimally invasive detection include colorimetric method or electrochemical method, that is, blood samples are collected from fingers or other human tissues, and then the blood is inhaled by the test strip on the blood glucose detector through the macroscopic effect to measure blood glucose concentration. The advantage of minimally invasive testing is that patients can operate it by themselves, which is convenient and practical in daily life, but because of this, if the operation is not done properly or the disinfection is not perfect during the collection process, the patient may be infected with other diseases or infected. Using this method for long-term blood sugar measurement will also bring certain risks to patients, and each measurement requires blood collection and consumption of disposable test strips. The procedures are complicated. These problems also limit the number of times patients can be tested, thus affecting blood sugar Overall effectiveness of monitoring.
因此，需要一种无创血糖检测技术来克服有创和微创检测所存在的上述问题。Therefore, there is a need for a non-invasive blood glucose detection technology to overcome the above-mentioned problems in invasive and minimally invasive detection.
发明内容Contents of the invention
本发明的目的在于提供一种用于检测血糖的方法及装置。The purpose of the present invention is to provide a method and device for detecting blood sugar.
据本发明的一方面，提供一种用于检测血糖的方法，所述方法包括：使用LED照射器向人体的待测部位照射可见红光；通过光电接收器采集从人体的待测部位透射的可见红光的动态光谱信息，所述动态光谱信息为随着人体的心脏的收缩和舒张而发生周期性变化的光电容积脉搏波；根据采集的动态光谱信息确定人体的血糖浓度值。According to one aspect of the present invention, a method for detecting blood sugar is provided, the method comprising: using an LED irradiator to irradiate visible red light to a part of the human body to be tested; The dynamic spectral information of visible red light is the photoplethysmographic pulse wave that changes periodically with the contraction and relaxation of the heart of the human body; the blood sugar concentration value of the human body is determined according to the collected dynamic spectral information.
优选地，所述可见红光的波长在700nm至800nm之间。Preferably, the visible red light has a wavelength between 700nm and 800nm.
优选地，所述根据采集的动态光谱信息确定人体的血糖浓度值的步骤包括：使用人体的血糖预测模型来根据采集的动态光谱信息确定人体的血糖浓度值，所述血糖预测模型包括人体的待测部位的动态光谱信息与人体的血糖浓度真值之间的对应关系。Preferably, the step of determining the blood sugar concentration value of the human body according to the collected dynamic spectral information includes: using the blood sugar prediction model of the human body to determine the blood sugar concentration value of the human body according to the collected dynamic spectral information. The corresponding relationship between the dynamic spectral information of the measurement site and the true value of the blood sugar concentration of the human body.
优选地，所述方法还包括：使用先前在人体的待测部位针对所述可见红光而采集的动态光谱信息和相应的人体的血糖浓度真值来构建所述血糖预测模型。Preferably, the method further includes: constructing the blood glucose prediction model by using the dynamic spectral information previously collected for the visible red light at the site to be measured of the human body and the corresponding true value of the blood glucose concentration of the human body.
优选地，所述血糖预测模型在包括ARM处理器的便携式设备中运行。Preferably, the blood glucose prediction model runs on a portable device including an ARM processor.
优选地，所述LED照射器和所述光电接收器分别布置在夹持装置的用于夹持人体的待测部位的相对的两个夹持件上。Preferably, the LED illuminator and the photoelectric receiver are respectively arranged on two opposite clamping parts of the clamping device for clamping the part to be measured of the human body.
优选地，人体的待测部位为人体的手指前端。Preferably, the part of the human body to be measured is the front end of a finger of the human body.
据本发明的另一方面，提供一种用于检测血糖的装置，所述装置包括：红光照射单元，使用LED照射器向人体的待测部位照射可见红光；光谱采集单元，通过光电接收器采集从人体的待测部位透射的可见红光的动态光谱信息，所述动态光谱信息为随着人体的心脏的收缩和舒张而发生周期性变化的光电容积脉搏波；血糖浓度确定单元，根据采集的动态光谱信息确定人体的血糖浓度值。According to another aspect of the present invention, a device for detecting blood sugar is provided, and the device includes: a red light irradiation unit, which uses an LED illuminator to irradiate visible red light to the part of the human body to be tested; The device collects the dynamic spectral information of the visible red light transmitted from the part to be measured of the human body, and the dynamic spectral information is a photoplethysmographic pulse wave that periodically changes with the contraction and relaxation of the heart of the human body; the blood glucose concentration determination unit, according to The collected dynamic spectrum information determines the blood glucose concentration value of the human body.
优选地，所述可见红光的波长在700nm至800nm之间。Preferably, the visible red light has a wavelength between 700nm and 800nm.
优选地，所述血糖浓度确定单元使用人体的血糖预测模型来根据采集的动态光谱信息确定人体的血糖浓度值，所述血糖预测模型包括人体的待测部位的动态光谱信息与人体的血糖浓度真值之间的对应关系。Preferably, the blood glucose concentration determination unit uses a blood glucose prediction model of the human body to determine the blood glucose concentration value of the human body according to the collected dynamic spectral information, and the blood glucose prediction model includes the dynamic spectral information of the part of the human body to be measured and the true blood glucose concentration of the human body. Correspondence between values.
优选地，所述装置还包括：模型构建单元，使用先前在人体的待测部位针对所述可见红光而采集的动态光谱信息和相应的人体的血糖浓度真值来构建所述血糖预测模型。Preferably, the device further includes: a model building unit, which uses the dynamic spectrum information previously collected for the visible red light at the part of the human body to be measured and the corresponding true value of the blood sugar concentration of the human body to build the blood sugar prediction model.
优选地，所述血糖预测模型在包括ARM处理器的便携式设备中运行。Preferably, the blood glucose prediction model runs on a portable device including an ARM processor.
优选地，所述LED照射器和所述光电接收器分别布置在夹持装置的用于夹持人体的待测部位的相对的两个夹持件上。Preferably, the LED illuminator and the photoelectric receiver are respectively arranged on two opposite clamping parts of the clamping device for clamping the part to be measured of the human body.
优选地，人体的待测部位为人体的手指前端。Preferably, the part of the human body to be measured is the front end of a finger of the human body.
本发明所提供的用于检测血糖的方法及装置能够使得血糖测量系统的整体体积变小，便于携带，操作简单，使用方便，并且在低功耗的情况下能够获得较稳定的数据信息。另外，利用光电容积脉搏波进行分析能够减少对人体皮肤组织、肤色、粗糙程度及测量位置变化对测量结果的影响，同时还避免了有创和微创的采血的方法对人体所造成的创伤。此外，所述方法及装置通过采集不同波长下的透射光信号还能够进一步提高血糖检测的稳定性及准确性。The method and device for detecting blood sugar provided by the present invention can make the overall volume of the blood sugar measuring system smaller, easy to carry, easy to operate, easy to use, and can obtain relatively stable data information under the condition of low power consumption. In addition, the use of photoplethysmography for analysis can reduce the influence of human skin tissue, skin color, roughness and measurement position changes on the measurement results, and at the same time avoid the trauma caused to the human body by invasive and minimally invasive blood collection methods. In addition, the method and device can further improve the stability and accuracy of blood glucose detection by collecting transmitted light signals at different wavelengths.
附图说明Description of drawings
通过下面结合附图进行的描述，本发明的目的和特点将会变得更加清楚，其中：Through the following description in conjunction with the accompanying drawings, the purpose and characteristics of the present invention will become more clear, wherein:
图1是示出根据本发明的示例性实施例的用于检测血糖的方法的流程图；FIG. 1 is a flowchart illustrating a method for detecting blood sugar according to an exemplary embodiment of the present invention;
图2是示出根据本发明的示例性实施例的用于检测血糖的装置的结构框图；FIG. 2 is a structural block diagram showing a device for detecting blood sugar according to an exemplary embodiment of the present invention;
图3是示出根据本发明的示例性实施例的葡萄糖溶液针对全波段光谱的吸光度的示意图；3 is a schematic diagram showing the absorbance of a glucose solution for a full-band spectrum according to an exemplary embodiment of the present invention;
图4是示出根据本发明的示例性实施例的光电容积脉搏波的示意图；4 is a schematic diagram illustrating a photoplethysmography wave according to an exemplary embodiment of the present invention;
图5是示出根据本发明的示例性实施例的利用ARM处理器来控制夹持装置检测血糖的系统的结构示意图。Fig. 5 is a schematic structural diagram showing a system for controlling a clamping device to detect blood sugar by using an ARM processor according to an exemplary embodiment of the present invention.
具体实施方式Detailed ways
根据血液中葡萄糖的化学结构式可知，葡萄糖中产生吸收作用的官能团主要包括C-H(甲基)，O-H(羟基)。当光源照射血液时，血液中的分子对该波段的光具有吸收作用，从而产生跃迁，在跃迁过程中分子吸收能量，进而产生了吸收光光谱(即，透射光光谱)。吸收光光谱的变化中包含了大量有机化合物的组成和分子结构信息，这使得吸收光光谱的变化能够更好地反映血液中的物质成分。According to the chemical structural formula of glucose in the blood, it can be seen that the functional groups that produce absorption in glucose mainly include C-H (methyl) and O-H (hydroxyl). When the light source irradiates the blood, the molecules in the blood absorb the light of this wavelength band, thereby generating a transition. During the transition, the molecules absorb energy, thereby generating the absorbed light spectrum (ie, the transmitted light spectrum). The change of the absorption spectrum contains a large amount of information about the composition and molecular structure of organic compounds, which makes the change of the absorption spectrum better reflect the material composition in the blood.
通常，波长为1500nm以上的长波红外线穿透皮肤深度较浅并且仅能作用到皮肤的表层组织，而波长为780nm至1500nm的短波红外线及波长为622nm至780nm的可见红光能够透射人体的组织并且直接作用到人体的血管、淋巴管、神经末梢及其他皮下组织。因此，可选择上述短波红外线和可见红光作为LED照射器的照射光源。Generally, long-wave infrared rays with a wavelength of 1500nm or more penetrate the skin at a shallow depth and can only act on the superficial tissue of the skin, while short-wave infrared rays with a wavelength of 780nm to 1500nm and visible red light with a wavelength of 622nm to 780nm can penetrate the tissues of the human body and It directly acts on the blood vessels, lymphatic vessels, nerve endings and other subcutaneous tissues of the human body. Therefore, the above-mentioned short-wave infrared ray and visible red light can be selected as the irradiation light source of the LED irradiator.
图3是示出根据本发明的示例性实施的葡萄糖溶液针对全波段光谱的吸光度的示意图。FIG. 3 is a schematic diagram showing the absorbance of a glucose solution for a full-band spectrum according to an exemplary implementation of the present invention.
参照图3，葡萄糖溶液存在吸收峰的波段(即，葡萄糖溶液在一段波长范围内的吸光度存在较大或急剧的变化量且方向向下)能够更好地对物质成分进行反映。在上述短波红外线和可见红光的波长范围内，葡萄糖溶液在700nm至800nm、1000nm至1100nm的波长范围内的吸收峰较为明显。Referring to FIG. 3 , the band where the glucose solution has an absorption peak (that is, the absorbance of the glucose solution has a large or sharp change in a wavelength range and the direction is downward) can better reflect the material composition. Within the wavelength ranges of the above-mentioned short-wave infrared rays and visible red light, the absorption peaks of the glucose solution in the wavelength ranges of 700nm to 800nm and 1000nm to 1100nm are relatively obvious.
考虑到人体血液中除了血糖之外还包含许多的其他物质成分(诸如，水、血红蛋白和脂肪)，因此，为了避免这些其他物质成分对光的吸收干扰，应避开血液中的其他物质成分在具有强的吸收峰的波段。Considering that human blood contains many other substances besides blood sugar (such as water, hemoglobin and fat), therefore, in order to avoid the interference of these other substances on light absorption, other substances in blood should be avoided Bands with strong absorption peaks.
在900nm至1300nm的波长范围内，血色素、蛋白质等物质成分都具有较强的吸收峰。在1300nm至1850nm的波长范围内，主要是水和脂肪的倍频振动吸收峰，各种物质成分的吸收谱峰相互交叠，会使得采集的信号包含合频振动吸收峰与倍频振动吸收峰，从而导致采集的信号的谱带较宽，重叠性较高，不利于进行精准的定量分析。In the wavelength range from 900nm to 1300nm, material components such as hemoglobin and protein all have strong absorption peaks. In the wavelength range from 1300nm to 1850nm, there are mainly double-frequency vibration absorption peaks of water and fat, and the absorption spectrum peaks of various material components overlap each other, which will make the collected signal contain combined frequency vibration absorption peaks and double-frequency vibration absorption peaks , resulting in a wide spectral band and high overlap of the collected signal, which is not conducive to accurate quantitative analysis.
然而，在700nm至800nm的波长范围内，血糖不仅具有强的吸收峰，而且基本上不存在上述各种物质成分的吸收谱峰相互交叠的问题。因此，为了对血糖检测进行精准的定量分析，在本发明中，可选用波长在700nm至800nm之间的可见红光作为血糖检测的照射光源。However, in the wavelength range of 700nm to 800nm, blood sugar not only has a strong absorption peak, but basically there is no problem that the absorption spectrum peaks of the above-mentioned various material components overlap with each other. Therefore, in order to perform accurate quantitative analysis on blood sugar detection, in the present invention, visible red light with a wavelength between 700 nm and 800 nm can be selected as the irradiation light source for blood sugar detection.
以下，将参照附图来详细说明本发明的利用可见红光来检测血糖的实施例。Hereinafter, an embodiment of detecting blood sugar by using visible red light of the present invention will be described in detail with reference to the accompanying drawings.
图1是示出根据本发明的示例性实施例的用于检测血糖的方法的流程图。FIG. 1 is a flowchart illustrating a method for detecting blood sugar according to an exemplary embodiment of the present invention.
在步骤110中，使用LED照射器向人体的待测部位(诸如，手指前端等)照射可见红光。In step 110, an LED illuminator is used to irradiate visible red light to the part of the human body to be tested (such as the tip of a finger, etc.).
其中，可见红光的波长范围可在700nm至800nm之间，并且如前面所描述的，在所述可见红光的照射下，人体的血液中的除血糖之外的其他物质成分(诸如，水、血红蛋白和脂肪)对采集的动态光谱信息所产生的干扰可被降到最小。Wherein, the wavelength range of the visible red light can be between 700nm and 800nm, and as described above, under the irradiation of the visible red light, other material components (such as water) in the blood of the human body except blood sugar , hemoglobin and fat) can be minimized to the interference of the collected dynamic spectral information.
在步骤120中，通过光电接收器采集从人体的待测部位透射的可见红光的动态光谱信息，所述动态光谱信息为随着人体的心脏的收缩和舒张而发生周期性变化的光电容积脉搏波。In step 120, the dynamic spectral information of the visible red light transmitted from the part to be measured of the human body is collected by the photoelectric receiver, and the dynamic spectral information is the photoplethysmographic pulse that changes periodically with the contraction and relaxation of the heart of the human body Wave.
图4是示出根据本发明的示例性实施例的光电容积脉搏波的示意图。FIG. 4 is a schematic diagram illustrating a photoplethysmography wave according to an exemplary embodiment of the present invention.
如图4所示，在可见红光Io经由人体的组织、血管和血液透射过人体的待测部位之后，可根据吸光度的变化信息(诸如，吸光度的最大值Imax，吸光度的最小值Imin)来获得透射的可见红光随着人体的心脏的收缩和舒张而发生周期性变化的动态光谱信息。As shown in Figure 4, after the visible red light Io is transmitted through the human body's tissues, blood vessels and blood through the human body to be measured, according to the change information of the absorbance (such as the maximum value Imax of the absorbance, the minimum value I max of the absorbancemin ) to obtain the dynamic spectral information that the transmitted visible red light changes periodically with the contraction and relaxation of the human heart.
在步骤130中，根据采集的动态光谱信息确定人体的血糖浓度值。In step 130, the blood glucose concentration value of the human body is determined according to the collected dynamic spectral information.
作为示例，可使用人体的血糖预测模型来根据采集的动态光谱信息确定人体的血糖浓度值，所述血糖预测模型包括人体的待测部位的动态光谱信息与人体的血糖浓度真值之间的对应关系。这种对应关系可以一维线性函数关系，也可以是多维非线性函数关系。作为示例，人体的血糖浓度真值可通过有创或微创的血糖检测方式来被获得。As an example, the human body's blood sugar prediction model can be used to determine the blood sugar concentration value of the human body according to the collected dynamic spectral information, and the blood sugar prediction model includes the correspondence between the dynamic spectral information of the part of the human body to be measured and the true value of the human body's blood sugar concentration relation. This corresponding relationship can be a one-dimensional linear functional relationship, or a multi-dimensional nonlinear functional relationship. As an example, the true value of the blood glucose concentration of the human body can be obtained through invasive or minimally invasive blood glucose detection methods.
在此之前，可使用先前在人体的待测部位针对可见红光而采集的动态光谱信息和相应的人体的血糖浓度真值来构建血糖预测模型。另外，在建模之前还可对采集的数据进行预处理，以减小采集过程中的系统误差对血糖预测模型的预测结果的影响，并对采集的动态光谱信息的数据进行平滑、叠加、平均处理，以提高动态光谱信息的信号的信噪比，从而为后续建模提供更为精准的数据依据。Prior to this, the blood glucose prediction model can be constructed by using the dynamic spectral information previously collected for the visible red light at the part of the human body to be measured and the corresponding true value of the blood glucose concentration of the human body. In addition, the collected data can be preprocessed before modeling to reduce the influence of systematic errors in the collection process on the prediction results of the blood glucose prediction model, and smooth, superimpose, and average the data of the collected dynamic spectral information Processing to improve the signal-to-noise ratio of the signal of dynamic spectral information, so as to provide more accurate data basis for subsequent modeling.
在上述实施例中，还可在700nm至800nm之间选用多种波长的可见红光来采集不同的动态光谱信息数据进行分析，以进一步提高预测结果的精度及稳定性。In the above embodiment, visible red light with various wavelengths between 700nm and 800nm can also be selected to collect different dynamic spectral information data for analysis, so as to further improve the accuracy and stability of the prediction results.
图2是示出根据本发明的示例性实施例的用于检测血糖的装置的结构框图。FIG. 2 is a structural block diagram illustrating an apparatus for detecting blood sugar according to an exemplary embodiment of the present invention.
参照图2，图2所示的装置可包括红光照射单元210、光谱采集单元220和血糖浓度确定单元230。红光照射单元210可使用LED照射器向人体的待测部位照射可见红光。光谱采集单元220可通过光电接收器采集从人体的待测部位透射的可见红光的动态光谱信息，该动态光谱信息为随着人体的心脏的收缩和舒张而发生周期性变化的光电容积脉搏波。血糖浓度确定单元230可根据采集的动态光谱信息确定人体的血糖浓度值。Referring to FIG. 2 , the device shown in FIG. 2 may include a red light irradiation unit 210 , a spectrum acquisition unit 220 and a blood glucose concentration determination unit 230 . The red light irradiation unit 210 may use an LED irradiator to irradiate visible red light to the part of the human body to be measured. The spectrum collection unit 220 can collect the dynamic spectrum information of the visible red light transmitted from the part of the human body to be measured through the photoelectric receiver, and the dynamic spectrum information is a photoplethysmography wave that changes periodically with the contraction and relaxation of the heart of the human body. . The blood glucose concentration determination unit 230 may determine the blood glucose concentration value of the human body according to the collected dynamic spectral information.
在图2所示的装置中，可见红光的波长可在700nm至800nm之间，并且在所述可见红光的照射下，人体的血液中的除血糖之外的其他物质成分对采集的动态光谱信息所产生的干扰可被降到最小。In the device shown in Figure 2, the wavelength of the visible red light can be between 700nm and 800nm, and under the irradiation of the visible red light, other material components in the blood of the human body except blood sugar can affect the dynamics of the collection. Interference from spectral information can be minimized.
在图2所示的装置中，血糖浓度确定单元230可使用人体的血糖预测模型来根据采集的动态光谱信息确定人体的血糖浓度值，所述血糖预测模型包括人体的待测部位的动态光谱信息与人体的血糖浓度真值之间的对应关系。In the device shown in FIG. 2 , the blood glucose concentration determination unit 230 can use the blood glucose prediction model of the human body to determine the blood glucose concentration value of the human body according to the collected dynamic spectral information, and the blood glucose prediction model includes the dynamic spectral information of the parts of the human body to be measured Correspondence between the blood sugar concentration and the true value of the human body.
此外，图2所示的装置还包括模型构建单元(未示出)，模型构建单元可使用先前在人体的待测部位针对可见红光而采集的动态光谱信息和相应的人体的血糖浓度真值来构建血糖预测模型。In addition, the device shown in Fig. 2 also includes a model building unit (not shown), the model building unit can use the dynamic spectrum information previously collected for the visible red light at the part of the human body to be measured and the corresponding true value of the blood glucose concentration of the human body To build a blood sugar prediction model.
图5是示出根据本发明的示例性实施例的利用ARM处理器来控制夹持装置检测血糖的系统的结构示意图。Fig. 5 is a schematic structural diagram showing a system for controlling a clamping device to detect blood sugar by using an ARM processor according to an exemplary embodiment of the present invention.
参照图5，图5中所示的系统可包括LED照射器401、光电接收器402、ARM处理器403、信号处理器404、血糖显示器405和夹持装置406。血糖预测模型可运行在ARM处理器403上，相应地，图2所示的红光照射单元210、光谱采集单元220和血糖浓度确定单元230可被包括在ARM处理器403中，以使得所述系统可使用ARM处理器403来对整个血糖检测过程进行控制。Referring to FIG. 5 , the system shown in FIG. 5 may include an LED illuminator 401 , a photoelectric receiver 402 , an ARM processor 403 , a signal processor 404 , a blood glucose display 405 and a clamping device 406 . The blood glucose prediction model can run on the ARM processor 403, and accordingly, the red light irradiation unit 210, the spectrum acquisition unit 220 and the blood glucose concentration determination unit 230 shown in FIG. 2 can be included in the ARM processor 403, so that the The system can use the ARM processor 403 to control the entire blood glucose detection process.
如图所示，可通过ARM处理器403使用LED照射器401向夹持装置406所夹持的人体的手指前端照射可见红光，并且通过光电接收器402采集从人体的手指前端透射的可见红光的动态光谱信息。采集的动态光谱信息可经由信号处理器404转换、放大和过滤，然后被传送至ARM处理器403中，以使用ARM处理器403中运行的血糖预测模型来根据采集的动态光谱信息确定人体的血糖浓度值。采集的动态光谱信息和确定的血糖浓度值均可显示在血糖显示器405上，以供使用者进行查看。As shown in the figure, the ARM processor 403 can use the LED illuminator 401 to irradiate visible red light to the front end of the finger of the human body clamped by the clamping device 406, and the visible red light transmitted from the front end of the finger of the human body can be collected by the photoelectric receiver 402. Dynamic spectral information of light. The collected dynamic spectral information can be converted, amplified and filtered by the signal processor 404, and then sent to the ARM processor 403, so as to use the blood glucose prediction model running in the ARM processor 403 to determine the blood glucose of the human body according to the collected dynamic spectral information concentration value. Both the collected dynamic spectrum information and the determined blood glucose concentration value can be displayed on the blood glucose display 405 for users to view.
此外，ARM处理器403还可从与其连接的上位机407(诸如，台式机)下载和更新血糖预测模型，以使其血糖预测结果更为精准。In addition, the ARM processor 403 can also download and update the blood glucose prediction model from a host computer 407 (such as a desktop computer) connected to it, so as to make the blood glucose prediction result more accurate.
另外，在图5所示的系统中，ARM处理器403可包括在便携式设备中，便携式设备可以以有线/或无线的通信方式连接至LED照射器401和光电接收器402，并且LED照射器401和光电接收器402可分别布置在夹持装置406的用于夹持人体的手指前端的相对的两个夹持件上。In addition, in the system shown in FIG. 5, the ARM processor 403 may be included in a portable device, and the portable device may be connected to the LED illuminator 401 and the photoelectric receiver 402 in a wired/or wireless communication manner, and the LED illuminator 401 The photoelectric receiver 402 and the photoelectric receiver 402 can be respectively arranged on two opposite clamping parts of the clamping device 406 for clamping the front end of the finger of the human body.
上述实施方式能够使得血糖测量系统的整体体积变小，便于携带，操作简单，使用方便，并且在低功耗的情况下能够获得较稳定的数据信息。另外，利用光电容积脉搏波进行分析能够减少对人体皮肤组织、肤色、粗糙程度及测量位置变化对测量结果的影响，同时还避免了有创和微创的采血的方法对人体所造成的创伤。此外，上述实施方式通过采集不同波长下的透射光信号还能够进一步提高血糖检测的稳定性及准确性。The above embodiments can make the overall volume of the blood glucose measurement system smaller, easy to carry, easy to operate, easy to use, and can obtain relatively stable data information under the condition of low power consumption. In addition, the use of photoplethysmography for analysis can reduce the influence of human skin tissue, skin color, roughness and measurement position changes on the measurement results, and at the same time avoid the trauma caused to the human body by invasive and minimally invasive blood collection methods. In addition, the above embodiments can further improve the stability and accuracy of blood glucose detection by collecting transmitted light signals at different wavelengths.
根据本发明的示例性实施例还提供一种存储有计算机程序的计算机可读存储介质。该计算机可读存储介质存储有当被处理器执行时使得处理器执行根据本发明的用于检测血糖的方法的计算机程序。该计算机可读记录介质是可存储由计算机系统读出的数据的任意数据存储装置。计算机可读记录介质的示例包括：只读存储器、随机存取存储器、只读光盘、磁带、软盘、光数据存储装置和载波(诸如经有线或无线传输路径通过互联网的数据传输)。Exemplary embodiments according to the present invention also provide a computer-readable storage medium storing a computer program. The computer-readable storage medium stores a computer program that, when executed by a processor, causes the processor to execute the method for detecting blood sugar according to the present invention. The computer-readable recording medium is any data storage device that can store data read by a computer system. Examples of computer-readable recording media include: read-only memory, random-access memory, optical disc, magnetic tape, floppy disk, optical data storage devices, and carrier waves (such as data transmission over the Internet via wired or wireless transmission paths).
根据本发明的示例性实施例还提供一种计算机设备。该计算机设备包括处理器和存储器。存储器用于存储计算机程序。所述计算机程序被处理器执行使得处理器执行根据本发明的用于检测血糖的方法的计算机程序。There is also provided a computer device according to an exemplary embodiment of the present invention. The computer device includes a processor and memory. Memory is used to store computer programs. The computer program is executed by the processor so that the processor executes the computer program of the method for detecting blood sugar according to the present invention.
尽管已参照优选实施例表示和描述了本申请，但本领域技术人员应该理解，在不脱离由权利要求限定的本申请的精神和范围的情况下，可以对这些实施例进行各种修改和变换。Although the present application has been shown and described with reference to preferred embodiments, it will be understood by those skilled in the art that various modifications and changes may be made to these embodiments without departing from the spirit and scope of the present application as defined by the claims .
| Application Number | Priority Date | Filing Date | Title |
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| CN201910812317.8ACN110575182A (en) | 2019-08-30 | 2019-08-30 | Method and device for detecting blood sugar |
| Application Number | Priority Date | Filing Date | Title |
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| CN201910812317.8ACN110575182A (en) | 2019-08-30 | 2019-08-30 | Method and device for detecting blood sugar |
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| CN110575182Atrue CN110575182A (en) | 2019-12-17 |
| Application Number | Title | Priority Date | Filing Date |
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| CN201910812317.8APendingCN110575182A (en) | 2019-08-30 | 2019-08-30 | Method and device for detecting blood sugar |
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