CN110567746A - An experimental system for simulating in vivo prostate motion measurements - Google Patents

Abstract

Translated fromChinese

本发明公开了一种用于模拟体内前列腺运动测量的实验系统，它涉及医疗技术领域，所述的步进电机用来控制丝杠滑台的进给，丝杠滑台与支撑架之间通过螺纹连接，支撑架与气筒之间也通过螺纹连接，气球套在气筒前端位置并形成一体嵌套在保持架内，系统中的气球用来模拟膀胱，粘接于气球上的小球用来模拟前列腺，小球上的传感器用来检测小球随着气球的膨胀或收缩而引起的位置变化，并可通过上位机实时显示。利用该实验系统可以探究由于膀胱充盈度导致的前列腺运动变化规律，有利于提高前列腺癌的放疗精度。此外，可将模拟前列腺的运动数据进行采集，可为研究人员提供一定的数据支持。

The invention discloses an experimental system for simulating the measurement of prostate movement in the body, which relates to the field of medical technology. The stepping motor is used to control the feed of the lead screw slide table, and the lead screw slide table and the support frame pass through Threaded connection, the support frame and the gas cylinder are also connected by threads, the balloon is set at the front end of the gas cylinder and nested in the cage as a whole, the balloon in the system is used to simulate the bladder, and the small ball bonded to the balloon is used to simulate For the prostate, the sensor on the ball is used to detect the position change of the ball as the balloon expands or contracts, and can be displayed in real time through the host computer. The experimental system can be used to explore the changes in prostate motion caused by bladder filling, which is conducive to improving the accuracy of radiotherapy for prostate cancer. In addition, the motion data of the simulated prostate can be collected, which can provide researchers with certain data support.

Description

Translated fromChinese

一种用于模拟体内前列腺运动测量的实验系统An experimental system for simulating in vivo prostate motion measurements

技术领域technical field

本发明属于医疗技术领域，特别是一种用于模拟体内前列腺运动测量的实验系统。The invention belongs to the field of medical technology, in particular to an experimental system for simulating the measurement of prostate motion in vivo.

背景技术Background technique

目前，放疗技术仍是临床上治疗癌症的一种有效手段。在放疗时为了能够有效杀死肿瘤细胞，传统的方法是增大肿瘤的外放边界，使得肿瘤区域能完全被射线照射到，但这会损伤正常的组织细胞，极易引发术后并发症。研究学者们也相继提出可以采用呼吸门控技术、四维立体放疗等对患者的呼吸运动进行补偿。然而，对前列腺肿瘤进行放疗时仍然存在着一些不确定因素，其中，尚未解决的问题是膀胱充盈度也会导致前列腺发生位移，从而会影响前列腺的定位精度。尽管可以采用机械固定等方式来限制由于膀胱的充盈导致前列腺发生运动，但是也会损伤患者的身体，从而影响患者的治疗效果。因此，在进行临床手术放疗时考虑膀胱充盈度对前列腺位置的影响是很有必要的。At present, radiotherapy technology is still an effective means of clinical treatment of cancer. In order to effectively kill tumor cells during radiotherapy, the traditional method is to enlarge the outer boundary of the tumor so that the tumor area can be completely irradiated by radiation, but this will damage normal tissue cells and easily cause postoperative complications. Researchers have also successively proposed that respiratory gating technology and four-dimensional radiotherapy can be used to compensate the patient's respiratory movement. However, there are still some uncertainties in the radiotherapy of prostate tumors. Among them, the unresolved problem is that the filling of the bladder will also cause the displacement of the prostate, which will affect the positioning accuracy of the prostate. Although mechanical fixation and other methods can be used to limit the movement of the prostate due to the filling of the bladder, it will also damage the patient's body, thereby affecting the therapeutic effect of the patient. Therefore, it is necessary to consider the impact of bladder filling on the position of the prostate when performing clinical surgery and radiotherapy.

基于以上现状，设计一种用于模拟体内前列腺运动测量的实验系统就显得尤为重要。利用该实验系统可以探究由于膀胱充盈度导致的前列腺运动变化规律，有利于提高前列腺癌的放疗精度。此外，可将前列腺的运动数据进行采集，可为研究人员提供一定的数据支持。Based on the above situation, it is particularly important to design an experimental system for simulating the measurement of prostate motion in vivo. The experimental system can be used to explore the changes in prostate motion caused by bladder filling, which is conducive to improving the accuracy of radiotherapy for prostate cancer. In addition, the movement data of the prostate can be collected, which can provide certain data support for researchers.

发明内容Contents of the invention

针对上述问题，本发明要解决的技术问题是提供一种用于模拟体内前列腺运动测量的实验系统。In view of the above problems, the technical problem to be solved by the present invention is to provide an experimental system for simulating the measurement of prostate motion in vivo.

本发明的一种用于模拟体内前列腺运动测量的实验系统，它包含小球、保持架、气筒、支撑架、丝杠滑台、步进电机、驱动器、控制器、底板A、固定板、底板B、气球、传感器，其特征在于：所述的小球与气球粘接连接并形成一体，保持架包括孔A、孔B、孔C以及保持架主体，保持架与底板A之间通过螺钉连接，气筒通过孔B、孔C嵌套在保持架内，气球套在气筒前端位置并形成一体，并与孔C之间形成过盈配合，支撑架包括螺纹孔A、螺纹孔B以及支撑架主体，气筒与支撑架之间通过螺纹连接，丝杠滑台与支撑架之间通过螺纹连接，驱动器置于底板A上表面，控制器置于底板A上表面，固定板置于底板A上表面，固定板与底板A之间通过螺纹连接，底板B置于底板A上表面并通过螺钉连接，传感器与小球之间粘接连接。The present invention is an experimental system for simulating the measurement of prostate movement in vivo, which includes a small ball, a cage, an air cylinder, a support frame, a lead screw slide, a stepping motor, a driver, a controller, a base plate A, a fixed plate, and a base plate B. The balloon and the sensor are characterized in that: the small ball and the balloon are bonded and connected to form a whole, the cage includes hole A, hole B, hole C and the cage main body, and the cage and the bottom plate A are connected by screws , the gas cylinder is nested in the cage through hole B and hole C, the balloon sleeve is integrated at the front end of the gas cylinder, and forms an interference fit with hole C, and the support frame includes threaded hole A, threaded hole B and the main body of the support frame , the gas cylinder and the support frame are connected by threads, the screw slide table and the support frame are connected by threads, the driver is placed on the upper surface of the bottom plate A, the controller is placed on the upper surface of the bottom plate A, the fixing plate is placed on the upper surface of the bottom plate A, The fixed plate and the bottom plate A are connected by threads, the bottom plate B is placed on the upper surface of the bottom plate A and connected by screws, and the sensor and the small ball are bonded.

作为优选，所述的传感器可通过USB转TTL串口与计算机连接，通过上位机可以实时显示小球的位置变化，并可将小球的数据输出，可为研究人员提供一个数据平台。Preferably, the sensor can be connected to a computer through a USB-to-TTL serial port, and the host computer can display the position change of the ball in real time, and can output the data of the ball, which can provide a data platform for researchers.

本发明的有益效果为：The beneficial effects of the present invention are:

（1）利用建立的实验系统可以探究由于膀胱充盈度导致的前列腺运动变化规律，有利于提高前列腺癌的放疗精度。(1) The established experimental system can be used to explore the changes in prostate motion caused by bladder filling, which is conducive to improving the accuracy of radiotherapy for prostate cancer.

（2）传感器可通过USB转TTL串口与计算机连接，通过上位机可以实时显示小球的位置变化，并可将小球的数据输出，可为研究人员提供一个数据平台。(2) The sensor can be connected to the computer through the USB-to-TTL serial port, and the position change of the ball can be displayed in real time through the host computer, and the data of the ball can be output, which can provide a data platform for researchers.

（3）整套系统结构简单，多处为螺纹连接，便于维修使用，且对环境污染小，具有一定的实用性。(3) The entire system has a simple structure, and many parts are threaded connections, which is convenient for maintenance and use, and has little environmental pollution, so it has certain practicability.

附图说明：Description of drawings:

为了易于说明，本发明由下述的具体实施及附图作以详细描述。For ease of illustration, the present invention is described in detail by the following specific implementations and accompanying drawings.

图1为系统的整体结构示意图Figure 1 is a schematic diagram of the overall structure of the system

图2为保持架的结构示意图Figure 2 is a schematic diagram of the structure of the cage

图3为支撑架的结构示意图Figure 3 is a schematic diagram of the structure of the support frame

图中：1小球、2保持架、2-1孔A、2-2孔B、2-3孔C、2-4保持架主体、3气筒、4支撑架、4-1螺纹孔A、4-2螺纹孔B、4-3支撑架主体、5丝杠滑台、6步进电机、7驱动器、8控制器、9底板A、10固定板、11底板B、12气球、13传感器。In the figure: 1 small ball, 2 cage, 2-1 hole A, 2-2 hole B, 2-3 hole C, 2-4 cage body, 3 gas cylinder, 4 support frame, 4-1 threaded hole A, 4-2 Threaded hole B, 4-3 Main body of support frame, 5 Lead screw slide, 6 Stepper motor, 7 Driver, 8 Controller, 9 Bottom plate A, 10 Fixed plate, 11 Bottom plate B, 12 Balloon, 13 Sensor.

具体实施方式：Detailed ways:

为使本发明的目的、技术方案和优点更加清楚明了，下面通过附图中示出的具体实施例来描述本发明。但是应该理解，这些描述只是示例性的，而并非要限制本发明的范围。此外，在以下说明中，省略了对公知结构和技术的描述，以避免不必要地混淆本发明的概念。In order to make the object, technical solution and advantages of the present invention clearer, the present invention is described below through specific embodiments shown in the accompanying drawings. It should be understood, however, that these descriptions are illustrative only and are not intended to limit the scope of the present invention. Also, in the following description, descriptions of well-known structures and techniques are omitted to avoid unnecessarily obscuring the concept of the present invention.

实施例1：如图1、图2、图3所示，本发明具体实施方式采用以下技术方案：一种用于模拟体内前列腺运动测量的实验系统，它包含小球1、保持架2、气筒3、支撑架4、丝杠滑台5、步进电机6、驱动器7、控制器8、底板A9、固定板10、底板B11、气球12、传感器13，其特征在于：所述的小球1与气球12粘接连接并形成一体，保持架2包括孔A2-1、孔B2-2、孔C2-3以及保持架主体2-4，保持架2与底板A9之间通过螺钉连接，气筒3通过孔B2-2、孔C2-3嵌套在保持架2内，气球12套在气筒3前端位置并形成一体，并与孔C2-3之间形成过盈配合，支撑架4包括螺纹孔A4-1、螺纹孔B4-2以及支撑架主体4-3，气筒3与支撑架4之间通过螺纹连接，丝杠滑台5与支撑架4之间通过螺纹连接，驱动器7置于底板A9上表面，控制器8置于底板A9上表面，固定板10置于底板A9上表面，固定板10与底板A9之间通过螺纹连接，底板B11置于底板A9上表面并通过螺钉连接，传感器（13）与小球1之间粘接连接。Embodiment 1: as shown in Fig. 1, Fig. 2, Fig. 3, the specific embodiment of the present invention adopts following technical proposal: a kind of experimental system for simulating in vivo prostate motion measurement, it comprises bead 1, cage 2, gas cylinder 3. Support frame 4, screw slide table 5, stepping motor 6, driver 7, controller 8, base plate A9, fixed plate 10, base plate B11, balloon 12, sensor 13, characterized in that: the small ball 1 It is bonded and connected with the balloon 12 and formed into one body. The cage 2 includes hole A2-1, hole B2-2, hole C2-3 and the cage main body 2-4. The cage 2 and the bottom plate A9 are connected by screws. The air cylinder 3 The hole B2-2 and the hole C2-3 are nested in the cage 2, the balloon 12 is set at the front end of the gas cylinder 3 and formed into one body, and forms an interference fit with the hole C2-3, and the support frame 4 includes a threaded hole A4 -1. Threaded hole B4-2 and the main body of the support frame 4-3, the air cylinder 3 and the support frame 4 are connected by threads, the screw slide table 5 and the support frame 4 are connected by threads, and the driver 7 is placed on the bottom plate A9 On the surface, the controller 8 is placed on the upper surface of the base plate A9, the fixed plate 10 is placed on the upper surface of the base plate A9, the fixed plate 10 and the base plate A9 are connected by threads, the base plate B11 is placed on the upper surface of the base plate A9 and connected by screws, and the sensor (13 ) and the adhesive connection between the ball 1.

进一步的，所述的传感器13可通过USB转TTL串口与计算机连接，通过上位机可以实时显示小球1的位置变化，并可将小球1的数据输出，可为研究人员提供一个数据平台。Further, the sensor 13 can be connected to a computer through a USB to TTL serial port, and the host computer can display the position change of the ball 1 in real time, and can output the data of the ball 1, which can provide a data platform for researchers.

以上显示和描述了本发明的基本原理和主要特征和本发明的优点。本行业的技术人员应该了解，本发明不受上述实施例的限制，上述实施例和说明书中描述的只是说明本发明的原理，在不脱离本发明精神和范围的前提下，本发明还会有各种变化和改进，这些变化和改进都落入要求保护的本发明范围内。本发明要求保护范围有所附的权利要求书及其等效物界定。The basic principles and main features of the present invention and the advantages of the present invention have been shown and described above. Those skilled in the industry should understand that the present invention is not limited by the above-mentioned embodiments. What are described in the above-mentioned embodiments and the description only illustrate the principle of the present invention. Without departing from the spirit and scope of the present invention, the present invention will also have Variations and improvements are possible, which fall within the scope of the claimed invention. The protection scope of the present invention is defined by the appended claims and their equivalents.

Claims (2)

1. The utility model provides an experimental system for be used for simulating internal prostate motion measurement, it contains bobble (1), holder (2), inflator (3), support frame (4), lead screw slip table (5), step motor (6), driver (7), controller (8), bottom plate A (9), fixed plate (10), bottom plate B (11), balloon (12), sensor (13), its characterized in that: the small ball (1) is connected with the balloon (12) in an adhesive way and is integrated, the retainer (2) comprises a hole A (2-1), a hole B (2-2), a hole C (2-3) and a retainer main body (2-4), the retainer (2) is connected with the bottom plate A (9) through a screw, the inflator (3) is embedded in the retainer (2) through the hole B (2-2) and the hole C (2-3), the balloon (12) is sleeved at the front end of the inflator (3) and is integrated with the hole C (2-3) in an interference fit way, the support frame (4) comprises a threaded hole A (4-1), a threaded hole B (4-2) and a support frame main body (4-3), the inflator (3) is connected with the support frame (4) through threads, the lead screw sliding table (5) is connected with the support frame (4) through threads, the driver (7) is arranged on the upper surface of the base plate A (9), the controller (8) is arranged on the upper surface of the base plate A (9), the fixing plate (10) is in threaded connection with the base plate A (9), the base plate B (11) is arranged on the upper surface of the base plate A (9) and is in screw connection with the base plate A (9), and the sensor (13) is in adhesive connection with the small ball (1).

2. an experimental system for simulating in vivo prostate movement measurements according to claim 1, characterized in that: the sensor (13) can be connected with a computer through a USB-to-TTL serial port, the position change of the small ball (1) can be displayed in real time through the upper computer, the data of the small ball (1) can be output, and a data platform can be provided for researchers.