技术领域technical field
本发明属于保健食品领域，本发明涉及一种纯天然黑茶含片的制备方法。The invention belongs to the field of health food, and relates to a preparation method of pure natural black tea lozenges.
背景技术Background technique
牙齿不仅代表着人的仪容仪表，更关系到全身的生命健康。随着现代人生活质量的提高和科学文明的飞速发展，人们的牙齿与口腔健康意识增强，都想拥有一副整洁美丽的牙齿，许多人已经认识到口腔健康的重要性。科学研究表明，健康的口腔可以预防口腔异味，保证人们在社交活动中的良好形象。能够拥有一口洁白整齐的牙齿，会为你增添更多的个人魅力，但现实却是，现代人由于吸烟等不健康生活方式导致大部分都有口腔疾病。据《2017年中国国民口腔健康状况调查报告》显示：91.6％的接受调查人群都曾受到口腔问题的困扰，其中女性用户的比例为92.0％，男性用户为91.4％，在口腔问题困扰方面，男女两者数据无明显性别差异。因此开发出有益口腔健康的保健品成为当前人们的迫切需要。Teeth not only represent a person's appearance, but also relate to the life and health of the whole body. With the improvement of the quality of life of modern people and the rapid development of scientific civilization, people's awareness of teeth and oral health has increased, and they all want to have a clean and beautiful set of teeth. Many people have realized the importance of oral health. Scientific research shows that a healthy mouth can prevent bad breath and ensure people's good image in social activities. Being able to have a mouthful of white and neat teeth will add more personal charm to you, but the reality is that most modern people have oral diseases due to unhealthy lifestyles such as smoking. According to the "2017 China National Oral Health Survey Report", 91.6% of the surveyed people have been troubled by oral problems, including 92.0% of female users and 91.4% of male users. In terms of oral problems, men and women There was no significant gender difference between the two data. Therefore develop the health product that is beneficial to oral health and become the urgent need of current people.
发明内容Contents of the invention
为弥补现有技术的不足，本发明提供一种纯天然黑茶含片的制备方法，该方法制备出具有护齿利咽功效的黑茶含片，该含片成分合理，配比得当，茶香明显，甜度适宜，成本较低，可以达到防治龋齿、清新口气、利咽清喉及维护口腔健康的目的，提高生活质量。In order to make up for the deficiencies in the prior art, the present invention provides a method for preparing pure natural black tea buccal tablets. The method prepares black tea buccal tablets with the effect of protecting teeth and relieving throat. The buccal tablets have reasonable ingredients and proper proportions. The fragrance is obvious, the sweetness is suitable, and the cost is low. It can achieve the purpose of preventing dental caries, refreshing breath, clearing throat and maintaining oral health, and improving the quality of life.
本发明的上述目的是通过以下技术方案实现的：Above-mentioned purpose of the present invention is achieved through the following technical solutions:
一种纯天然黑茶含片的制备方法，包括如下步骤：A preparation method of pure natural dark tea lozenges, comprising the steps of:
(1)按质量份数称取茯砖茶粉碎，过60目筛，获得茯砖茶粉；加入质量为茶粉总重25倍的水量在超声波提取装置中，室温下超声浸提30min，离心过滤得到提取液A和茶粉渣B；(1) Weigh Fuzhuan brick tea according to the number of parts by mass, pulverize it, and pass through a 60-mesh sieve to obtain Fuzhuan brick tea powder; add water with a quality 25 times the total weight of the tea powder in an ultrasonic extraction device, ultrasonically extract for 30 minutes at room temperature, and centrifugally filter to obtain Extract A and tea powder residue B;
(2)向茶粉渣B中加入其质量15倍的清水室温下超声浸提20min，离心过滤得到提取液C和茶粉渣D；(2) Add 15 times the mass of clear water to the tea powder B and ultrasonically extract at room temperature for 20 minutes, and centrifugally filter to obtain extract C and tea powder D;
(3)向茶粉渣D中加入其质量10倍的清水室温下超声浸提10min，离心过滤得到提取液E和茶粉渣F；(3) Add 10 times the mass of clear water to the tea powder D and ultrasonically extract at room temperature for 10 minutes, and centrifugally filter to obtain extract E and tea powder F;
(4)将提取液A、提取液C与提取液E均匀混合得到水提物G，减压浓缩(0.06Mpa)得浓缩液H，保存待用；(4) Uniformly mix the extract A, the extract C and the extract E to obtain the water extract G, and concentrate under reduced pressure (0.06Mpa) to obtain the concentrate H, which is stored for later use;
(5)按质量份数称取原料金银花，蒲公英，胖大海，板蓝根，桔梗，薄荷，甘草清洗，粉碎过60目筛，获得混合草药粉；加入质量为草药粉总重25倍的水量在超声波提取装置中，室温下超声浸提30min，离心过滤得到提取液I和茶粉渣J；(5) Take by weight raw material honeysuckle, dandelion, fat sea, Radix Isatidis, Campanulaceae, peppermint, licorice, wash, pulverize and pass through a 60 mesh sieve to obtain mixed herbal medicine powder; add quality 25 times of the total weight of herbal powder in ultrasonic In the extraction device, ultrasonic leaching at room temperature for 30 minutes, and centrifugal filtration to obtain extract I and tea powder residue J;
(6)向茶粉渣J中加入其质量15倍的清水室温下超声浸提20min，离心过滤得到提取液L和茶粉渣M；(6) Add 15 times the mass of clear water to the tea powder J and ultrasonically extract at room temperature for 20 minutes, and centrifugally filter to obtain extract L and tea powder M;
(7)向茶粉渣M中加入其质量10倍的清水室温下超声浸提10min，离心过滤得到提取液N和茶粉渣O；(7) Add 10 times the quality of water to the tea powder M at room temperature for ultrasonic extraction for 10 minutes, and centrifugally filter to obtain extract N and tea powder O;
(8)将提取液I、提取液L与提取液N均匀混合得到水提物P，减压浓缩(0.06Mpa)得浓缩液Q，保存待用；(8) Uniformly mix the extract I, the extract L and the extract N to obtain the water extract P, and concentrate under reduced pressure (0.06Mpa) to obtain the concentrate Q, which is stored for later use;
(9)将浓缩液H与浓缩液Q进行混合，加入填充剂和湿润剂后置混合机中充分混合20分钟，至色泽均匀一致；(9) Mix the concentrated solution H with the concentrated solution Q, add the filler and the wetting agent and mix them in the mixer for 20 minutes until the color is uniform;
(10)将上述混合后的物料喷雾制粒后加入自动压片机中，压制成片状物；(10) After spraying and granulating the above-mentioned mixed material, add it into an automatic tablet press, and press it into a tablet;
(11)将片状物置于紫外线灯下照射3-5min后进行包装，从而得到黑茶含片。(11) Put the flakes under an ultraviolet lamp and irradiate for 3-5 minutes before packaging, so as to obtain dark tea buccal tablets.
进一步的，步骤(1)中超声波提取装置功率为350W。Further, the power of the ultrasonic extraction device in step (1) is 350W.
进一步的，步骤(9)所述的填充剂为异麦芽糖醇和木糖醇。Further, the filler described in step (9) is isomalt and xylitol.
进一步的，步骤(9)所述的湿润剂为水。Further, the wetting agent described in step (9) is water.
上述纯天然黑茶含片的的制备方法制备具有护齿利咽功效的黑茶含片，包括如下质量份数的原料制备而成：茯砖茶30-40份，金银花20-30份，蒲公英10-15份，胖大海10-15份，板蓝根8-10份，桔梗8-10份，薄荷3-5份，异麦芽糖醇10-15份，木糖醇5-8份，甘草3-5份。The preparation method of the above-mentioned pure natural black tea buccal tablet prepares the black tea buccal tablet with the effect of protecting teeth and relieving throat. -15 parts, 10-15 parts of fat sea, 8-10 parts of isatidis, 8-10 parts of bellflower, 3-5 parts of mint, 10-15 parts of isomalt, 5-8 parts of xylitol, 3-5 parts of licorice .
进一步的，包括如下质量份数的原料制备而成：茯砖茶30份，金银花20份，蒲公英10份，胖大海10份，板蓝根8份，桔梗8份，薄荷3份，异麦芽糖醇10份，木糖醇5份，甘草3份。Further, it is prepared from the following raw materials in parts by mass: 30 parts of fuzhuan brick tea, 20 parts of honeysuckle, 10 parts of dandelion, 10 parts of fat sea, 8 parts of isatidis, 8 parts of bellflower, 3 parts of mint, 10 parts of isomalt, 5 parts of xylitol, 3 parts of licorice.
进一步的，包括如下质量份数的原料制备而成：茯砖茶35份，金银花25份，蒲公英12份，胖大海12份，板蓝根9份，桔梗9份，薄荷4份，异麦芽糖醇13份，木糖醇7份，甘草4份。Further, it is prepared from the following raw materials in parts by mass: 35 parts of Fuzhuan brick tea, 25 parts of honeysuckle, 12 parts of dandelion, 12 parts of Panda Dahai, 9 parts of Radix Radix, 9 parts of bellflower, 4 parts of mint, 13 parts of isomalt, 7 parts of xylitol, 4 parts of licorice.
进一步的，包括如下质量份数的原料制备而成：茯砖茶40份，金银花30份，蒲公英15份，胖大海15份，板蓝根10份，桔梗10份，薄荷5份，异麦芽糖醇15份，木糖醇8份，甘草5份。Further, it is prepared from the following raw materials in parts by mass: 40 parts of Fuzhuan brick tea, 30 parts of honeysuckle, 15 parts of dandelion, 15 parts of Panda Hai, 10 parts of Radix Radix, 10 parts of bellflower, 5 parts of mint, 15 parts of isomalt, 8 parts of xylitol, 5 parts of licorice.
茯砖茶属于六大茶类黑茶中的珍贵品种，自古就有“生命之茶”的美誉。茯砖茶中的多酚类化合物(儿茶素类、黄酮类、花青素和酚酸类等)是活性很强的抗氧化剂，不但能使烟草中的尼古丁发生沉淀，并随小便排出体外，还能清除烟气中的自由基，降低烟气对人体毒害作用；茶多酚能够抑制口臭的主要成分——甲硫醇的产生，能够很好的清新口气；再者，茶多酚具有清除自由基作用，可增强口腔黏膜抵抗力和代谢能力，从而保护口腔黏膜的完整性。不仅如此，茶多酚还可抑制溃疡面的细菌生长繁殖，增强黏膜的再生能力。Fuzhuan tea is a precious variety among the six major types of dark tea, and has been known as the "tea of life" since ancient times. The polyphenolic compounds (catechins, flavonoids, anthocyanins and phenolic acids, etc.) in Fuzhuan brick tea are highly active antioxidants, which can not only precipitate nicotine in tobacco, but also excrete it with urine. It can also remove free radicals in the smoke and reduce the toxic effect of smoke on the human body; tea polyphenols can inhibit the production of methyl mercaptan, the main component of bad breath, and can refresh the breath; moreover, tea polyphenols have the ability to remove The action of free radicals can enhance the resistance and metabolism of oral mucosa, thereby protecting the integrity of oral mucosa. Not only that, tea polyphenols can also inhibit the growth and reproduction of bacteria on the ulcer surface, and enhance the regeneration ability of the mucous membrane.
茯砖茶中含氟量较高，每100克茶中含氟量为10毫克至15毫克，且80％为水溶性成分。若每人每天饮茶叶10克，则可以吸收水溶性氟1-5毫克，而且茶叶属碱性，可抑制人体钙质的减少，这对于预防龋齿、护齿、坚齿都是有益的。据有关资料显示，在小学生中进行“饭后茶疗漱口”实验，龋齿率可降低80％。The fluorine content in Fuzhuan brick tea is relatively high, and the fluorine content per 100 grams of tea is 10 mg to 15 mg, and 80% of them are water-soluble components. If each person drinks 10 grams of tea per day, they can absorb 1-5 mg of water-soluble fluorine, and tea is alkaline, which can inhibit the reduction of calcium in the human body, which is beneficial for preventing dental caries, protecting teeth, and strengthening teeth. According to relevant data, the dental caries rate can be reduced by 80% in the experiment of "gargling with tea after meals" among primary school students.
本发明中所用的金银花自古以来就以它的药用价值广泛而著名。其功效主要是清热解毒，还能抑制与杀灭咽喉部的病原菌；薄荷含有八种儿茶萘酚酸，对口腔有一定的消炎作用；蒲公英被称为天然抗生素，对牙周炎、牙龈炎、口腔炎等炎症有很好的疗效，能够改善因这些口腔炎症引起的口臭问题；板蓝根具有清热解毒，凉血利咽之功效；胖大海具有清肺热、利咽喉、解毒、润肠通便之功效。用于肺热声哑、咽喉疼痛、热结便秘以及用嗓过度等引发的声音嘶哑等症。甘草含有甘草酸、甘草甙等营养物质，能补脾益气，祛痰止咳，缓急止痛，调和诸药，常用于咽喉肿痛、咳嗽痰多、口腔溃疡等症；桔梗含有的桔梗皂苷对口腔、咽喉的直接刺激，有抗炎、宣开肺气等作用。The honeysuckle used in the present invention is just widely famous with its medicinal value since ancient times. Its effect is mainly to clear away heat and detoxify, and can also inhibit and kill pathogenic bacteria in the throat; peppermint contains eight kinds of catechin naphtholic acids, which have a certain anti-inflammatory effect on the oral cavity; It has a good curative effect on inflammations such as stomatitis and stomatitis, and can improve the bad breath caused by these stomatitis; Banlangen has the effect of clearing away heat and detoxification, cooling blood and relieving throat; Panda Dahai has the effect of clearing lung heat, benefiting throat, detoxifying, moistening intestines and defecating The effect. It is used for hoarseness caused by lung heat, sore throat, constipation caused by heat knot, and excessive voice use. Licorice root contains nutrients such as glycyrrhizic acid and glycyrrhizin, which can invigorate the spleen and Qi, eliminate phlegm and relieve cough, relieve spasm and relieve pain, and reconcile various medicines. , The direct stimulation of the throat has the effects of anti-inflammation and opening the lungs.
异麦芽糖醇是一种优良的蔗糖替代品，其独特的理化性质、生理功能和食用安全性已经实验充分证实，其用量近年来急剧上升，在欧美等发达国家，已占据无糖食品所使用甜味剂50％以上市场。异麦芽糖醇具有以下特性：(1)适合糖尿病病人食用，不会引起血糖和胰岛素上升。(2)非致龋齿性，口腔内的变形链球菌不能分解利用，不产生酸和葡聚糖，不会造成蛀牙，特别适合儿童食用。(3)低热量，适合高血压、高血脂、肥胖及害怕肥胖的人群食用。(4)甜味纯正天然，可与其它强力甜味剂(如甜蜜素、甜菊糖)配合使用，掩盖其它强力甜味剂的不良味道。(5)高稳定性，异麦芽糖醇为多元糖醇，非常稳定，不会和食品中其他成份发生化学反应。异麦芽糖醇不能被绝大多数微生物利用，因此，使用异麦芽糖醇生产的产品具有更长的货架期。(6)非吸湿性，与蔗糖、葡萄糖或某些低聚糖相比异麦芽糖醇具有非常低的吸湿性。在25℃相对湿度为70％时，基本没有吸湿，便于包装和运输。(7)异麦芽酮糖醇是一种优良的双歧杆菌增殖因子，可以被人体肠道中的双歧杆菌所分解利用，促进双歧杆菌的生长繁殖，维持肠道的微生态平衡，有利于人体的健康。木糖醇则属于惰性较强的物质，在保质期内不影响药物疗效。Isomalt is an excellent substitute for sucrose. Its unique physical and chemical properties, physiological functions and food safety have been fully confirmed by experiments. Its consumption has risen sharply in recent years. Flavoring agents account for more than 50% of the market. Isomalt has the following characteristics: (1) It is suitable for diabetic patients and will not cause blood sugar and insulin to rise. (2) Non-cariogenic, Streptococcus mutans in the oral cavity cannot be decomposed and utilized, does not produce acid and glucan, does not cause tooth decay, and is especially suitable for children. (3) Low-calorie, suitable for people with high blood pressure, high blood fat, obesity and people who are afraid of obesity. (4) The sweet taste is pure and natural, and it can be used in conjunction with other strong sweeteners (such as cyclamate and stevia) to cover up the bad taste of other strong sweeteners. (5) High stability. Isomalt is a polysaccharide alcohol, which is very stable and will not react chemically with other ingredients in food. Isomalt cannot be utilized by the vast majority of microorganisms, therefore, products produced using isomalt have a longer shelf life. (6) Non-hygroscopicity, compared with sucrose, glucose or certain oligosaccharides, isomalt has very low hygroscopicity. When the relative humidity is 70% at 25°C, there is basically no moisture absorption, which is convenient for packaging and transportation. (7) Isomalt is an excellent bifidobacteria proliferation factor, which can be decomposed and utilized by bifidobacteria in the human intestinal tract, promotes the growth and reproduction of bifidobacteria, maintains the micro-ecological balance of the intestinal tract, and is beneficial Human health. Xylitol is a relatively inert substance and will not affect the efficacy of the drug during the shelf life.
本发明与现有技术相比的有益效果是：The beneficial effect of the present invention compared with prior art is:
(1)本发明的含片的主要成分均取材于纯天然中草药等，配比合理，在保留黑茶茶多酚多种功效的同时，富含微量元素、蛋白质、多种氨基酸、矿物质、有机酸、维生素及多种中药活性物质等成分，可清热解毒、凉血利咽、防治龋齿，清新口气，维护口腔健康。(1) The main components of the buccal tablet of the present invention are all drawn from pure natural Chinese herbal medicines, etc., with reasonable proportions. While retaining the multiple effects of black tea polyphenols, it is rich in trace elements, proteins, various amino acids, minerals, organic It can clear away heat and detoxify, cool blood and sore throat, prevent dental caries, freshen breath and maintain oral health.
(2)本发明无添加任何化学防腐剂、人造香精等成分，对人体无毒副作用。其中黑茶茶多酚具有抗菌广谱性，几乎涵盖了对自然界几乎所有的动、植物病原细菌的抑制能力，且不会使细菌产生耐药性；同时使用异麦芽糖醇、木糖醇可以保证产品不受空气中微生物的影响，保持原有特性及货架期。(2) The present invention does not add any chemical preservatives, artificial flavors and other ingredients, and has no toxic and side effects on the human body. Among them, black tea polyphenols have broad-spectrum antibacterial properties, covering almost all animal and plant pathogenic bacteria in nature, and will not make bacteria resistant; using isomalt and xylitol at the same time can ensure that the product It is not affected by microorganisms in the air and maintains its original characteristics and shelf life.
(3)本发明的黑茶含片兼有增强免疫力、调节肠胃功能、降脂、解食毒等养生功能，还可用于辅助治疗因吸烟造成的咽喉炎、气管炎、肺气肿等疾病，有助于呼吸道、肺部组织的康复。(3) The black tea buccal tablet of the present invention has the functions of enhancing immunity, regulating gastrointestinal function, reducing fat, detoxification, etc., and can also be used to assist in the treatment of pharyngitis, tracheitis, emphysema and other diseases caused by smoking , Contribute to the rehabilitation of respiratory tract and lung tissue.
(4)目前市面上的口含片为维持口感调节甜味而常常使用易吸湿的辅料如山梨醇等，因此市售的口含片往往会因吸湿过多而造成外观的变化甚至主药含量的下降。虽然各生产厂家采取了铝塑包装或铝袋包装等密封性较好的包装方法，但仍不能解决根本问题。因此本产品选取异麦芽糖醇为主要辅料，它大大降低了产品生产过程的吸湿，可显著增加产品的稳定性。(4) The buccal tablets currently on the market often use hygroscopic excipients such as sorbitol in order to maintain the taste and adjust the sweetness. Decline. Although each manufacturer has adopted better packaging methods such as aluminum-plastic packaging or aluminum bag packaging, the fundamental problem cannot be solved. Therefore, this product uses isomalt as the main auxiliary material, which greatly reduces the moisture absorption in the production process of the product and can significantly increase the stability of the product.
(5)传统饮茶方式虽不麻烦但也较为耗时，本发明利用现代制剂技术将茶叶与中草药由耗时的加工方式转变成携带、运输、服用均较方便的含片，且口感佳，质量好，功效强，天然绿色，成为一种全新的广大消费者保护口腔健康的优良选择，具有广阔的经济和社会效益前景。(5) Although the traditional method of drinking tea is not troublesome, it is also time-consuming. The present invention uses modern preparation technology to transform tea and Chinese herbal medicine from a time-consuming processing method into a lozenge that is more convenient to carry, transport, and take, and has a good taste. Good quality, strong efficacy, natural green, become a brand-new excellent choice for consumers to protect oral health, and have broad economic and social benefit prospects.
(6)对于长期吸烟人群来说，一支香烟可以破坏25～100mg维生素C。研究发现，吸烟者比不吸烟者血液中的维C少30％～50％，这是因为机体为对抗烟中的有害物质，消耗了更多的维生素C，身体内维生素C长期处于低水平而得不到补充，就会引发疾病。我国营养学会提出，维生素C对吸烟者的供给量应该是不吸烟者的2倍。本发明利用茶多酚与维生素C的增效作用使二者更利于人体吸收。原料中中草药的加入不仅增加了抗氧化功效，更重要的是都含有大量维生素C，能增强茶多酚对各种自由基的清除能力，可提高机体免疫力，保护吸烟人士身体健康。(6) For long-term smokers, a cigarette can destroy 25-100 mg of vitamin C. Studies have found that smokers have 30% to 50% less vitamin C in their blood than non-smokers. If it is not supplemented, it will cause disease. The Nutrition Society of my country proposes that the supply of vitamin C to smokers should be twice that of non-smokers. The present invention utilizes the synergistic effect of tea polyphenols and vitamin C to make the two more conducive to human body absorption. The addition of Chinese herbal medicine in the raw materials not only increases the antioxidant effect, but more importantly, it contains a large amount of vitamin C, which can enhance the ability of tea polyphenols to scavenge various free radicals, improve the body's immunity, and protect the health of smokers.
(7)金银花又名忍冬，有清热解毒、疏散风热的功效，具有“中药抗生素”、“绿色抗菌素”之称。金银花中含有的有机酸类包括绿原酸、异绿原酸和咖啡酸，不但对人体的新陈代谢也有着很好的改善作用，还能与蒲公英所含有的苦味质皂苷、天门冬素等成分共同作用，滋润肺腑，祛湿化痰。(7) Honeysuckle, also known as honeysuckle, has the effects of clearing away heat and detoxifying, evacuating wind-heat, and is known as "Chinese medicine antibiotic" and "green antibiotic". The organic acids contained in honeysuckle include chlorogenic acid, isochlorogenic acid and caffeic acid, which not only have a good effect on improving the metabolism of the human body, but also work together with the bitter saponins and asparagine contained in dandelion. Function, nourishes the lungs and organs, dispels dampness and resolves phlegm.
甘草本身补脾益气，其中含有的化学成分甘草甜素为清热泻火的主要成份；蒲公英性寒，又含有菊糖、胆碱等物质，两者协同作用可使解毒降火的作用更加显著；桔梗味苦，具有宣肺利咽、祛痰排脓的作用，主要成分为皂苷类及黄酮类化合物，可提升甘草抗炎物质的含量，此二者伍用，取甘草之泻火解毒以固本，取桔梗之宣通肺气以化痰止咳，标本兼顾，相得益彰，故其宣肺止咳，利咽解毒，祛痰排脓之功增强。另胖大海与甘草均入肺经，二者可以共清肺经之火，更好的治疗肺热引起的咽喉红肿、疼痛，声音嘶哑等症。Licorice itself nourishes the spleen and nourishes qi, and the chemical component glycyrrhizin contained in it is the main component of clearing heat and purging fire; dandelion is cold in nature, and contains inulin, choline and other substances. The synergistic effect of the two can make the effect of detoxification and reducing fire more significant ; Platycodon grandiflora is bitter in taste, has the functions of clearing the lung, relieving the throat, eliminating phlegm and discharging pus. The main components are saponins and flavonoids, which can increase the content of anti-inflammatory substances in licorice. Consolidate the root, take Platycodon grandiflorum to promote lung qi to reduce phlegm and relieve cough, taking into account both specimens and complementing each other, so it has the functions of promoting lung and relieving cough, relieving throat and detoxification, and eliminating phlegm and discharging pus. In addition, Panda Dahai and Licorice both enter the lung meridian, the two can clear the fire of the lung meridian together, and better treat throat redness, pain, hoarseness and other diseases caused by lung heat.
薄荷性凉，疏散风热，清利头目，且可解毒利咽；金银花、甘草气味芳香，既疏散风热，又清热解毒，又辟秽化浊，三者配伍，加强加强疏风散热之功，且可缓解咽痛症状。黑茶是后发酵茶，性温，去寒，和蒲公英、薄荷等一同配伍，可中和其寒性，使配方不会过温过凉而伤正，并且养胃解毒，生津去热，还可有效改善由于吸烟等口腔里残留的异味，起到清新口气的作用。Peppermint is cool in nature, disperses wind-heat, clears the head, and can detoxify and sore throat; honeysuckle and licorice are fragrant, not only evacuate wind-heat, but also clear away heat and detoxify, and repel filth and turbidity. , and can relieve sore throat symptoms. Dark tea is a post-fermented tea, warm in nature, cold-removing, compatible with dandelion, mint, etc., can neutralize its coldness, so that the formula will not be overheated or too cold and hurt the body. It can effectively improve the residual odor in the mouth due to smoking, etc., and play a role in refreshing breath.
(8)该含片的制作原料价格低，功效好，性价比极高，适宜长期食用；操作流程简单，便于制作。本发明中重要原料黑茶主要产自贵州省铜仁地区，有助于具有地方特色的保健食品业的发展。(8) The buccal tablet has low raw material prices, good efficacy, high cost performance, and is suitable for long-term consumption; the operation process is simple and convenient for production. The black tea, the important raw material of the present invention, is mainly produced in Tongren, Guizhou Province, which contributes to the development of the health food industry with local characteristics.
具体实施方式Detailed ways
下面通过具体实施例详述本发明，但不限制本发明的保护范围。如无特殊说明，本发明所采用的实验方法均为常规方法，所用实验器材、材料、试剂等均可从商业途径获得。The present invention is described in detail below through specific examples, but the protection scope of the present invention is not limited. Unless otherwise specified, the experimental methods used in the present invention are conventional methods, and the experimental equipment, materials, reagents, etc. used can be obtained from commercial sources.
实施例1Example 1
(1)按质量份数称取30份茯砖茶粉碎，过60目筛，获得茯砖茶粉；加入质量为茶粉总重25倍的水量在超声波提取装置中，室温下超声浸提30min，离心过滤得到提取液A和茶粉渣B；(1) Take 30 parts of Fuzhuan brick tea by weight and pulverize them, and pass through a 60-mesh sieve to obtain Fuzhuan brick tea powder; add water with a quality of 25 times the total weight of the tea powder in an ultrasonic extraction device, ultrasonically extract at room temperature for 30 minutes, and centrifuge Filter to obtain extract A and tea powder residue B;
(2)向茶粉渣B中加入其质量15倍的清水室温下超声浸提20min，离心过滤得到提取液C和茶粉渣D；(2) Add 15 times the mass of clear water to the tea powder B and ultrasonically extract at room temperature for 20 minutes, and centrifugally filter to obtain extract C and tea powder D;
(3)向茶粉渣D中加入其质量10倍的清水室温下超声浸提10min，离心过滤得到提取液E和茶粉渣F；(3) Add 10 times the mass of clear water to the tea powder D and ultrasonically extract at room temperature for 10 minutes, and centrifugally filter to obtain extract E and tea powder F;
(4)将提取液A、提取液C与提取液E均匀混合得到水提物G，减压浓缩(0.06Mpa)得浓缩液H，保存待用；(4) Uniformly mix the extract A, the extract C and the extract E to obtain the water extract G, and concentrate under reduced pressure (0.06Mpa) to obtain the concentrate H, which is stored for later use;
(5)按质量份数称取原料金银花20份，蒲公英10份，胖大海10份，板蓝根8份，桔梗8份，薄荷3份，异麦芽糖醇10份，木糖醇5份，甘草3份。将中草药清洗粉碎过60目筛，获得混合草药粉；加入质量为草药粉总重25倍的水量在超声波提取装置中，室温下超声浸提30min，离心过滤得到提取液I和茶粉渣J；(5) Weigh 20 parts of honeysuckle, 10 parts of dandelion, 10 parts of fat sea, 8 parts of Radix Radix, 8 parts of Campanulaceae, 3 parts of peppermint, 10 parts of isomalt, 5 parts of xylitol, and 3 parts of licorice . Wash and pulverize the Chinese herbal medicine through a 60-mesh sieve to obtain mixed herbal medicine powder; add water with a mass 25 times the total weight of the herbal medicine powder in an ultrasonic extraction device, perform ultrasonic extraction at room temperature for 30 minutes, and centrifugally filter to obtain the extract I and tea powder residue J;
(6)向茶粉渣J中加入其质量15倍的清水室温下超声浸提20min，离心过滤得到提取液L和茶粉渣M；(6) Add 15 times the mass of clear water to the tea powder J and ultrasonically extract at room temperature for 20 minutes, and centrifugally filter to obtain extract L and tea powder M;
(7)向茶粉渣M中加入其质量10倍的清水室温下超声浸提10min，离心过滤得到提取液N和茶粉渣O；(7) Add 10 times the quality of water to the tea powder M at room temperature for ultrasonic extraction for 10 minutes, and centrifugally filter to obtain extract N and tea powder O;
(8)将提取液I、提取液L与提取液N均匀混合得到水提物P，减压浓缩(0.06Mpa)得浓缩液Q，保存待用；(8) Uniformly mix the extract I, the extract L and the extract N to obtain the water extract P, and concentrate under reduced pressure (0.06Mpa) to obtain the concentrate Q, which is stored for later use;
(9)将浓缩液H与浓缩液Q进行混合，加入填充剂和湿润剂后置混合机中充分混合20分钟，至色泽均匀一致；(9) Mix the concentrated solution H with the concentrated solution Q, add the filler and the wetting agent and mix them in the mixer for 20 minutes until the color is uniform;
(10)将上述混合后的物料喷雾制粒后加入自动压片机中，压制成片状物。(10) Spray and granulate the above-mentioned mixed materials and put them into an automatic tablet press, and press them into tablets.
步骤(1)中超声波提取装置功率为350W。In step (1), the power of the ultrasonic extraction device is 350W.
步骤(9)所述的填充剂为异麦芽糖醇和木糖醇。The filler described in step (9) is isomalt and xylitol.
步骤(9)所述的湿润剂为水。The wetting agent described in step (9) is water.
实施例2Example 2
(1)按质量份数称取35份茯砖茶粉碎，过60目筛，获得茯砖茶粉；加入质量为茶粉总重25倍的水量在超声波提取装置中，室温下超声浸提30min，离心过滤得到提取液A和茶粉渣B；(1) Take 35 parts of Fuzhuan brick tea by weight and pulverize them, and pass through a 60-mesh sieve to obtain Fuzhuan brick tea powder; add water with a quality of 25 times the total weight of the tea powder in an ultrasonic extraction device, ultrasonically extract at room temperature for 30 minutes, and centrifuge Filter to obtain extract A and tea powder residue B;
(2)向茶粉渣B中加入其质量15倍的清水室温下超声浸提20min，离心过滤得到提取液C和茶粉渣D；(2) Add 15 times the mass of clear water to the tea powder B and ultrasonically extract at room temperature for 20 minutes, and centrifugally filter to obtain extract C and tea powder D;
(3)向茶粉渣D中加入其质量10倍的清水室温下超声浸提10min，离心过滤得到提取液E和茶粉渣F；(3) Add 10 times the mass of clear water to the tea powder D and ultrasonically extract at room temperature for 10 minutes, and centrifugally filter to obtain extract E and tea powder F;
(4)将提取液A、提取液C与提取液E均匀混合得到水提物G，减压浓缩(0.06Mpa)得浓缩液H，保存待用；(4) Uniformly mix the extract A, the extract C and the extract E to obtain the water extract G, and concentrate under reduced pressure (0.06Mpa) to obtain the concentrate H, which is stored for later use;
(5)按质量份数称取原料金银花25份，蒲公英12份，胖大海12份，板蓝根9份，桔梗9份，薄荷4份，异麦芽糖醇13份，木糖醇7份，甘草4份。将中草药清洗粉碎过60目筛，获得混合草药粉；加入质量为草药粉总重25倍的水量在超声波提取装置中，室温下超声浸提30min，离心过滤得到提取液I和茶粉渣J；(5) Weigh 25 parts of honeysuckle, 12 parts of dandelion, 12 parts of fat sea, 9 parts of isatidis, 9 parts of platycodon, 4 parts of peppermint, 13 parts of isomalt, 7 parts of xylitol, and 4 parts of licorice. . Wash and pulverize the Chinese herbal medicine through a 60-mesh sieve to obtain mixed herbal medicine powder; add water with a mass 25 times the total weight of the herbal medicine powder in an ultrasonic extraction device, perform ultrasonic extraction at room temperature for 30 minutes, and centrifugally filter to obtain the extract I and tea powder residue J;
(6)向茶粉渣J中加入其质量15倍的清水室温下超声浸提20min，离心过滤得到提取液L和茶粉渣M；(6) Add 15 times the mass of clear water to the tea powder J and ultrasonically extract at room temperature for 20 minutes, and centrifugally filter to obtain extract L and tea powder M;
(7)向茶粉渣M中加入其质量10倍的清水室温下超声浸提10min，离心过滤得到提取液N和茶粉渣O；(7) Add 10 times the quality of water to the tea powder M at room temperature for ultrasonic extraction for 10 minutes, and centrifugally filter to obtain extract N and tea powder O;
(8)将提取液I、提取液L与提取液N均匀混合得到水提物P，减压浓缩(0.06Mpa)得浓缩液Q，保存待用；(8) Uniformly mix the extract I, the extract L and the extract N to obtain the water extract P, and concentrate under reduced pressure (0.06Mpa) to obtain the concentrate Q, which is stored for later use;
(9)将浓缩液H与浓缩液Q进行混合，加入填充剂和湿润剂后置混合机中充分混合20分钟，至色泽均匀一致；(9) Mix the concentrated solution H with the concentrated solution Q, add the filler and the wetting agent and mix them in the mixer for 20 minutes until the color is uniform;
(10)将上述混合后的物料喷雾制粒后加入自动压片机中，压制成片状物。(10) Spray and granulate the above-mentioned mixed materials and put them into an automatic tablet press, and press them into tablets.
(11)将片状物置于紫外线灯下照射3-5min后进行包装，从而得到黑茶含片。(11) Put the flakes under an ultraviolet lamp and irradiate for 3-5 minutes before packaging, so as to obtain dark tea buccal tablets.
步骤(1)中超声波提取装置功率为350W。In step (1), the power of the ultrasonic extraction device is 350W.
步骤(9)所述的填充剂为异麦芽糖醇和木糖醇。The filler described in step (9) is isomalt and xylitol.
步骤(9)所述的湿润剂为水。The wetting agent described in step (9) is water.
实施例3Example 3
(1)按质量份数称取40份茯砖茶粉碎，过60目筛，获得茯砖茶粉；加入质量为茶粉总重25倍的水量在超声波提取装置中，室温下超声浸提30min，离心过滤得到提取液A和茶粉渣B；(1) Take 40 parts of Fuzhuan brick tea by weight and pulverize them, and pass through a 60-mesh sieve to obtain Fuzhuan brick tea powder; add water with a quality of 25 times the total weight of the tea powder in an ultrasonic extraction device, ultrasonically extract at room temperature for 30 minutes, and centrifuge Filter to obtain extract A and tea powder residue B;
(2)向茶粉渣B中加入其质量15倍的清水室温下超声浸提20min，离心过滤得到提取液C和茶粉渣D；(2) Add 15 times the mass of clear water to the tea powder B and ultrasonically extract at room temperature for 20 minutes, and centrifugally filter to obtain extract C and tea powder D;
(3)向茶粉渣D中加入其质量10倍的清水室温下超声浸提10min，离心过滤得到提取液E和茶粉渣F；(3) Add 10 times the mass of clear water to the tea powder D and ultrasonically extract at room temperature for 10 minutes, and centrifugally filter to obtain extract E and tea powder F;
(4)将提取液A、提取液C与提取液E均匀混合得到水提物G，减压浓缩(0.06Mpa)得浓缩液H，保存待用；(4) Uniformly mix the extract A, the extract C and the extract E to obtain the water extract G, and concentrate under reduced pressure (0.06Mpa) to obtain the concentrate H, which is stored for later use;
(5)按质量份数称取原料金银花30份，蒲公英15份，胖大海15份，板蓝根10份，桔梗10份，薄荷5份，异麦芽糖醇15份，木糖醇8份，甘草5份。(5) Weigh 30 parts of honeysuckle, 15 parts of dandelion, 15 parts of fat sea, 10 parts of isatidis, 10 parts of bellflower, 5 parts of peppermint, 15 parts of isomalt, 8 parts of xylitol, and 5 parts of licorice .
将中草药清洗粉碎过60目筛，获得混合草药粉；加入质量为草药粉总重25倍的水量在超声波提取装置中，室温下超声浸提30min，离心过滤得到提取液I和茶粉渣J；Wash and pulverize the Chinese herbal medicine through a 60-mesh sieve to obtain mixed herbal medicine powder; add water with a mass 25 times the total weight of the herbal medicine powder in an ultrasonic extraction device, perform ultrasonic extraction at room temperature for 30 minutes, and centrifugally filter to obtain the extract I and tea powder residue J;
(6)向茶粉渣J中加入其质量15倍的清水室温下超声浸提20min，离心过滤得到提取液L和茶粉渣M；(6) Add 15 times the mass of clear water to the tea powder J and ultrasonically extract at room temperature for 20 minutes, and centrifugally filter to obtain extract L and tea powder M;
(7)向茶粉渣M中加入其质量10倍的清水室温下超声浸提10min，离心过滤得到提取液N和茶粉渣O；(7) Add 10 times the quality of water to the tea powder M at room temperature for ultrasonic extraction for 10 minutes, and centrifugally filter to obtain extract N and tea powder O;
(8)将提取液I、提取液L与提取液N均匀混合得到水提物P，减压浓缩(0.06Mpa)得浓缩液Q，保存待用；(8) Uniformly mix the extract I, the extract L and the extract N to obtain the water extract P, and concentrate under reduced pressure (0.06Mpa) to obtain the concentrate Q, which is stored for later use;
(9)将浓缩液H与浓缩液Q进行混合，加入填充剂和湿润剂后置混合机中充分混合20分钟，至色泽均匀一致；(9) Mix the concentrated solution H with the concentrated solution Q, add the filler and the wetting agent and mix them in the mixer for 20 minutes until the color is uniform;
(10)将上述混合后的物料喷雾制粒后加入自动压片机中，压制成片状物。(10) Spray and granulate the above-mentioned mixed materials and put them into an automatic tablet press, and press them into tablets.
(11)将片状物置于紫外线灯下照射3-5min后进行包装，从而得到黑茶含片。(11) Put the flakes under an ultraviolet lamp and irradiate for 3-5 minutes before packaging, so as to obtain dark tea buccal tablets.
步骤(1)中超声波提取装置功率为350W。In step (1), the power of the ultrasonic extraction device is 350W.
步骤(9)所述的填充剂为异麦芽糖醇和木糖醇。The filler described in step (9) is isomalt and xylitol.
步骤(9)所述的湿润剂为水。The wetting agent described in step (9) is water.
将制成的黑茶含片进行感官评定，结果如下表1：The dark tea buccal tablet of making is carried out sensory evaluation, and result is as follows table 1:
表1黑茶含片感官评价表Table 1 Sensory evaluation form of dark tea lozenges
由上表1可知本产品发明制备的天然黑茶含片有明显草药香，茶香明显，外形光滑完整。与市售某茶含片相比，入口融化更慢，甜度适宜，更易被人们喜爱与接受。It can be seen from the above table 1 that the natural black tea buccal tablet prepared by the invention of this product has obvious herbal fragrance, obvious tea fragrance, smooth and complete shape. Compared with a commercially available tea lozenge, it melts more slowly in the mouth, has a suitable sweetness, and is easier to be loved and accepted by people.
临床实验clinical experiments
选取40名年龄在20-30岁的患有慢性咽炎、口腔溃疡、龋齿等症状的患者，平均分为两组，男女各半，分别服用实施例3制得含片和市售某具有保护口腔健康功能的含片，每隔1-2个小时含一次，一天使用6-8片，使用半个月，在使用该药物的过程中，不使用其他同类型药物，保持正常饮食作息，结果如下表2：Select 40 patients aged 20-30 years old who suffer from symptoms such as chronic pharyngitis, oral ulcers, and dental caries, and divide them into two groups on average, half men and half women, and take respectively the buccal tablets prepared in Example 3 and a commercially available certain oral cavity-protecting medicine. The lozenges with health function, containing once every 1-2 hours, use 6-8 tablets a day, use for half a month, in the process of using this drug, do not use other drugs of the same type, maintain normal diet and rest, the results are as follows Table 2:
表2患者服药效果表Table 2 Patient Medication Effect Table
典型案例分析Typical case analysis
病例1：曹某，男，26岁，患有轻度龋齿，牙周炎，常感咬合无力、钝痛，继发性牙龈出血。2018年12月开始服用实施例3的含片，服用5天左右，症状有所缓解，二十天后症状得以极大减轻。Case 1: Cao, male, 26 years old, suffered from mild dental caries, periodontitis, often felt occlusal weakness, dull pain, and secondary gingival bleeding. Begin to take the lozenge of embodiment 3 in December, 2018, take about 5 days, and symptom alleviates to some extent, and symptom can be greatly alleviated after 20 days.
病例2：蒋某，男，27岁，慢性咽喉炎4年，发病时咽部有异物感、发痒、咽干、咽痛、灼热、咳嗽、痰多不易咳净，讲话易疲劳，或于刷牙漱口，讲话多时易恶心作呕等。2018年12月开始服用实施例3的含片，服用4天左右，症状有所缓解，半个月后症状得以极大减轻。Case 2: Jiang, male, 27 years old, had chronic pharyngitis for 4 years. At the time of onset, there was a foreign body sensation in the throat, itching, dry throat, sore throat, burning, coughing, excessive phlegm that was difficult to clear, and fatigue when speaking. Brush your teeth and rinse your mouth, feel nauseous when you talk for a long time, etc. I started to take the lozenge of Example 3 in December 2018, and after taking it for about 4 days, the symptoms were relieved, and the symptoms were greatly relieved after half a month.
病例3：王某，男，25岁，口腔溃疡，2018年12月开始服用实施例3的含片，服用3天左右，症状有所减轻，1周左右痊愈。Case 3: Wang, male, 25 years old, suffered from oral ulcers. He began to take the lozenge of Example 3 in December 2018. After taking about 3 days, the symptoms were alleviated and healed in about 1 week.
病例4：蓝某，男，27岁，急性咽喉炎，初起出现咽部干燥、灼热，继之疼痛，吞咽及咳嗽时加重，并可出现声音嘶哑，讲话困难，有时伴发热，全身不适及食欲不振等。2018年12月开始服用实施例3的含片，服用3天左右，症状有所减轻，1周左右痊愈。Case 4: Lan, male, 27 years old, had acute pharyngitis. At the beginning, the throat was dry and hot, followed by pain, which aggravated when swallowing and coughing, and hoarseness, difficulty in speaking, sometimes accompanied by fever, general malaise and loss of appetite etc. Begin to take the lozenge of embodiment 3 in December, 2018, take about 3 days, symptom alleviates to some extent, recovers from illness in about 1 week.
以上所述实施方式仅为本发明的优选实施例，而并非本发明可行实施的全部实施例。对于本领域一般技术人员而言，在不背离本发明原理和精神的前提下对其所作出的任何显而易见的改动，都应当被认为包含在本发明的权利要求保护范围之内。The implementation manners described above are only preferred embodiments of the present invention, but not all feasible embodiments of the present invention. For those skilled in the art, any obvious changes made without departing from the principle and spirit of the present invention should be considered to be included in the protection scope of the claims of the present invention.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910875332.7ACN110522823A (en) | 2019-09-17 | 2019-09-17 | A kind of preparation method of pure natural dark tea buccal tablet |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910875332.7ACN110522823A (en) | 2019-09-17 | 2019-09-17 | A kind of preparation method of pure natural dark tea buccal tablet |
| Publication Number | Publication Date |
|---|---|
| CN110522823Atrue CN110522823A (en) | 2019-12-03 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910875332.7APendingCN110522823A (en) | 2019-09-17 | 2019-09-17 | A kind of preparation method of pure natural dark tea buccal tablet |
| Country | Link |
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| CN (1) | CN110522823A (en) |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116898085A (en)* | 2023-07-26 | 2023-10-20 | 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） | Instant wild jujube leaf worm tea lozenge and preparation method thereof |
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| CN1422655A (en)* | 2002-12-04 | 2003-06-11 | 西安高科陕西金方药业公司 | Throat lozenge |
| CN108740180A (en)* | 2018-05-04 | 2018-11-06 | 任秀江 | A kind of black tea lozenge and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116898085A (en)* | 2023-07-26 | 2023-10-20 | 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） | Instant wild jujube leaf worm tea lozenge and preparation method thereof |
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| RJ01 | Rejection of invention patent application after publication | Application publication date:20191203 | |
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