技术领域technical field
本发明涉及一种高性能半刚穿刺型微波消融天线，适用于无创或微创介入治疗手术，在支气管镜、胃镜、肠镜等高清晰内窥镜系统引导下对实体肿瘤实施微波消融治疗，属于医用微波技术应用领域。The invention relates to a high-performance semi-rigid puncture type microwave ablation antenna, which is suitable for non-invasive or minimally invasive interventional treatment operations, and performs microwave ablation treatment on solid tumors under the guidance of high-definition endoscope systems such as bronchoscopes, gastroscopes, and colonoscopes. It belongs to the application field of medical microwave technology.
背景技术Background technique
进入21世纪以来，随着现代影像技术的发展，国内外微创介入手术在临床应用上取得了日新月异的进展，其中微波消融治疗技术的拓展尤为迅速。近年来，肿瘤微波介入治疗愈益成熟，向着更加安全精准的目标迈进，而且悄然地向着无创介入的领域拓展。Since the beginning of the 21st century, with the development of modern imaging technology, the clinical application of minimally invasive interventional surgery at home and abroad has made rapid progress, among which the expansion of microwave ablation therapy technology is particularly rapid. In recent years, tumor microwave interventional therapy has become more and more mature, moving towards a safer and more precise goal, and quietly expanding to the field of non-invasive intervention.
在“高清晰内窥镜系统”的引导下，临床专家积极探索并成功地实践了无创伤性的对消化道、呼吸道、泌尿道治疗和微创伤性的胸腔、腹腔、关节腔等肿瘤治疗手术,如高频器械、氩等离子体、激光、射频等有源治疗技术纷纷成功地进入该领域。因此，微波技术向无创性治疗领域拓展必将为大势所趋。Under the guidance of "high-definition endoscopy system", clinical experts actively explored and successfully practiced non-invasive treatment of digestive tract, respiratory tract, urinary tract and micro-invasive thoracic cavity, abdominal cavity, joint cavity and other tumor treatment Surgery, such as high-frequency instruments, argon plasma, laser, radio frequency and other active treatment technologies have successfully entered the field. Therefore, the expansion of microwave technology to the field of non-invasive treatment is bound to be the general trend.
就医用微波技术而言，如何匹配在“高清晰内窥镜系统”引导下而安全有效地应用于无创性治疗领域，将成为关键性课题。As far as medical microwave technology is concerned, how to safely and effectively apply it to the field of non-invasive treatment under the guidance of the "high-definition endoscope system" will become a key issue.
目前，处于临床研究阶段的微波器械一种是纤维状微波消融针，其缺陷在于它采用的是编织型同轴电缆，因其细长（1.2-1.6米）针体，使之缺乏足够的柔韧度和前端足够的穿刺力，且针体外径又比较粗。另一种是半刚穿刺型水冷结构的微波消融针，其不足在于其结构外径较大，不适适宜配合较小内径的内窥镜引导，相对制约其在临床上的应用范围。At present, one of the microwave instruments in the clinical research stage is a fibrous microwave ablation needle. The defect is that it uses a braided coaxial cable. Because of its slender (1.2-1.6 meters) needle body, it lacks sufficient flexibility. The puncture force of the needle and the front end is sufficient, and the outer diameter of the needle is relatively thick. The other is a microwave ablation needle with a semi-rigid puncture type water-cooled structure, which has the disadvantage that its structure has a large outer diameter and is not suitable for guidance with an endoscope with a smaller inner diameter, which relatively restricts its clinical application range.
发明内容SUMMARY OF THE INVENTION
本发明分别克服了现有上述两种产品的缺陷和不足，提出一种高性能半刚穿刺型微波消融天线，能够在较小内径规格的内窥镜引导下进入人体腔道内，在内窥镜直视下按其导向穿刺介入靶向组织内，实施实体肿瘤的微波消融。The invention overcomes the defects and deficiencies of the two existing products respectively, and proposes a high-performance semi-rigid puncture microwave ablation antenna, which can enter the human body cavity under the guidance of an endoscope with a smaller inner diameter, and the endoscope Under direct vision, the guided puncture is inserted into the target tissue to perform microwave ablation of solid tumors.
本发明高性能半刚穿刺型微波消融天线，包括：三棱锥形穿刺头、介质管、半刚同轴电缆和外导套，其特征在于：所述半刚同轴电缆的内导体装入三棱锥形穿刺头尾部的圆柱体盲孔中，采用焊接并辅以压铆固定；所述介质管装套在穿刺头尾部的圆柱体上，涂以粘接剂固定；所述外导套前端的内孔装套在介质管尾部的台肩外圆上，同时其中心孔装套于所述半刚同轴电缆上，对二者接触部位采用气密性焊接固定。由此构成本发明前端辐射电磁波（微波）的场源结构，使其天线性能稳定，结构简单合理，对肿瘤组织的微波消融范围易于控制。The high-performance semi-rigid puncture microwave ablation antenna of the present invention comprises: a triangular pyramid-shaped puncture head, a medium tube, a semi-rigid coaxial cable and an outer guide sleeve, and is characterized in that: the inner conductor of the semi-rigid coaxial cable is inserted into three The blind hole of the cylinder at the tail of the pyramid-shaped puncture head is fixed by welding and riveting; the medium tube is sleeved on the cylinder at the tail of the puncture head and fixed with adhesive; the front end of the outer guide sleeve is The inner hole is sleeved on the outer circle of the shoulder at the end of the medium pipe, and the center hole is sleeved on the semi-rigid coaxial cable, and the contact parts of the two are fixed by air-tight welding. Therefore, the field source structure of the front-end radiation electromagnetic wave (microwave) of the present invention is formed, the antenna performance is stable, the structure is simple and reasonable, and the microwave ablation range of tumor tissue is easy to control.
本发明的进一步特征如下：Further features of the present invention are as follows:
1、所述穿刺头优选使用三棱锥形或圆锥形，材质可为铜质或不锈钢质的金属材料，具有足够的机械强度与穿刺力。1. The puncture head is preferably a triangular pyramid or a cone, and the material can be copper or stainless steel, with sufficient mechanical strength and puncturing force.
2、在所述半刚同轴电缆外表面装套有螺旋弹簧并延伸到天线体尾部，所述螺旋弹簧与半刚同轴电缆为松动配合，二者间隙以保持相对自由弯曲运动为宜。所述螺旋弹簧选用特种不锈钢丝绕制而成，并经热处理具有一定的柔韧性。2. A coil spring is sleeved on the outer surface of the semi-rigid coaxial cable and extends to the tail of the antenna body. The coil spring and the semi-rigid coaxial cable are loosely matched, and the gap between the two is suitable to maintain relatively free bending movement. The coil spring is made of special stainless steel wire and has certain flexibility after heat treatment.
3、在所述外导套台肩外圆表面上开设轴向沟槽，用以嵌入螺旋弹簧前端的钢丝，再机械力铆紧并辅以焊锡固定，使外导套与螺旋弹簧之间形成紧固连接。3. An axial groove is provided on the outer surface of the shoulder of the outer guide sleeve to embed the steel wire at the front end of the coil spring, and then mechanically riveted and fixed with solder, so that the outer guide sleeve and the coil spring are formed. Tighten the connection.
4、在所述外导套台肩外圆与螺旋弹簧外表面装套四氟管或热塑聚四氟管，所述四氟管延伸至天线体尾部。4. A tetrafluoro tube or a thermoplastic polytetrafluoro tube is installed on the outer circumference of the shoulder of the outer guide sleeve and the outer surface of the coil spring, and the tetrafluoro tube extends to the tail of the antenna body.
5、采用钢丝喉箍或钢丝绑扎方式，将薄壁四氟管固定于外导套台肩外圆表面。为此在所述外导套台肩外圆柱表面设有环状沟槽，以保证紧固薄壁四氟管与外导套无发生轴向窜动的可能。5. The thin-walled PTFE tube is fixed on the outer surface of the outer guide sleeve shoulder by using the wire hose hoop or the wire binding method. For this reason, an annular groove is provided on the outer cylindrical surface of the shoulder of the outer guide sleeve to ensure that there is no possibility of axial movement when the thin-walled PTFE tube and the outer guide sleeve are fastened.
6、在所述半刚同轴电缆的尾部装焊射频连接器，以馈送微波能量，其中半刚同轴电缆与射频连接器的内、外导体必须分别焊接牢靠，不得形成短路。6. A radio frequency connector is welded on the tail of the semi-rigid coaxial cable to feed microwave energy, and the inner and outer conductors of the semi-rigid coaxial cable and the radio frequency connector must be welded firmly, and no short circuit shall be formed.
7、所述螺旋弹簧和薄壁四氟套管的长度均比半刚同轴电缆长度短10-15毫米，以不干涉天线体的自由弯曲为宜。7. The lengths of the helical spring and the thin-walled PTFE sleeve are both 10-15 mm shorter than the length of the semi-rigid coaxial cable, so as not to interfere with the free bending of the antenna body.
8、在天线体尾部装配有手柄，其射频连接器压配并辅以粘接剂固定，柄管再从天线体前端装套与柄座粘接固定。8. A handle is installed at the end of the antenna body, and the radio frequency connector is press-fitted and fixed with an adhesive. The handle tube is then sleeved from the front end of the antenna body and fixed with the handle base.
综上所述，本发明的突出特点在于：（1）穿刺头有效地增加了半刚微波天线的穿刺力。（2）半刚同轴电缆作为本发明的微波传输同轴线与现有纤维状微波消融针的编织型同轴线相比较，提高了天线体的柔韧度，并有效地减少其微波传输损耗和发热量。（3）包裹在半刚同轴电缆外的螺旋密绕弹簧，不仅进一步增强了本发明天线体柔韧性，且有效地起到隔热与缓冲半刚同轴电缆热量对外围的辐射。由此与现有纤维状微波消融针相比，多一层隔热材料。（4）本发明天线体最外层的薄壁四氟管，不仅为本天线体隔热，而且其与内窥镜管壁之间具有很好的自润滑性。（5）本发明的天线体结构紧凑，有效地减小其自身外径，因此本发明可配套并适用于目前医院临床常用的进口高清晰内窥镜系统。To sum up, the outstanding features of the present invention are: (1) The puncturing head effectively increases the puncturing force of the semi-rigid microwave antenna. (2) The semi-rigid coaxial cable as the microwave transmission coaxial wire of the present invention improves the flexibility of the antenna body and effectively reduces the microwave transmission loss compared with the braided coaxial wire of the existing fibrous microwave ablation needle. and heat generation. (3) The helical densely wound spring wrapped outside the semi-rigid coaxial cable not only further enhances the flexibility of the antenna body of the present invention, but also effectively insulates and buffers the radiation of the semi-rigid coaxial cable heat to the periphery. Therefore, compared with the existing fibrous microwave ablation needle, there is an additional layer of heat insulating material. (4) The thin-walled tetrafluorotube in the outermost layer of the antenna body of the present invention not only insulates the antenna body, but also has good self-lubrication with the endoscope tube wall. (5) The antenna body of the present invention has a compact structure and can effectively reduce its own outer diameter, so the present invention can be matched and applied to imported high-definition endoscope systems commonly used in clinical clinics at present.
总之，本发明为肿瘤微波介入治疗技术在清晰可视的内窥镜引导下进入无创性治疗领域跨上了一个新的台阶。In a word, the present invention has reached a new level for the tumor microwave interventional therapy technology to enter the field of non-invasive therapy under the guidance of a clearly visible endoscope.
附图说明Description of drawings
下面结合附图对本发明作进一步的说明。The present invention will be further described below in conjunction with the accompanying drawings.
图1为本实施例一高性能半刚穿刺型微波消融天线前端结构示意图。FIG. 1 is a schematic structural diagram of the front end of a high-performance semi-rigid puncture microwave ablation antenna according to the present embodiment.
图2是本实施例一高性能半刚穿刺型微波消融天线尾部结构示意图。FIG. 2 is a schematic diagram of the structure of the tail of a high-performance semi-rigid puncture microwave ablation antenna according to the present embodiment.
图中的标号示意如下：The symbols in the figure are as follows:
1-三棱锥形穿刺头，2-介质管，3-半刚同轴电缆，4-外导套，5-钢丝卡箍，6-薄壁四氟管，7-螺旋弹簧，8-手柄管，9-手柄座，10-射频连接器。1-Triangular pyramid puncture head, 2-Media tube, 3-Semi-rigid coaxial cable, 4-Outer guide sleeve, 5-Wire clamp, 6-Thin-wall PTFE tube, 7-Coil spring, 8-Handle tube , 9-handle base, 10-RF connector.
具体实施方式Detailed ways
实施例一Example 1
如图1、图2所示，本实施例一的高性能半刚穿刺型微波消融天线，其组成三棱锥形穿刺头1，介质管2，半刚同轴电缆3，外导套4，薄壁四氟管6，钢丝卡箍5，螺旋弹簧7，手柄管8，手柄座9，射频连接器10。半刚同轴电缆3的内导体装入三棱锥形穿刺头1尾部的圆柱体盲孔中，采用焊接并辅以压铆固定；介质管2装套在三棱锥形穿刺头1尾部的圆柱体上，涂以粘接剂固定；外导套4前端的内孔装套在介质管2尾部的台肩外圆上，同时其中心孔装套于半刚同轴电缆3上，对二者接触部位采用气密性焊接固定。半刚同轴电缆3外套装有延伸至天线尾部的螺旋弹簧7，螺旋弹簧7与半刚同轴电缆3之间为松动配合。外导套2的尾部开设轴向沟槽，螺旋弹簧7前端的钢丝嵌入该轴向沟槽内进行固定，并通过机械力铆紧并辅以焊锡固定，使外导套与螺旋弹簧之间形成紧固连接。薄壁四氟管6套于螺旋弹簧7和外导套4外，并且其前端与外导套4固定。具体的，外导套4的外圆表面设有环状沟槽，通过钢丝卡箍5将薄壁四氟管6前端卡入环状沟槽内实现薄壁四氟管6的固定。As shown in Figures 1 and 2, the high-performance semi-rigid puncture microwave ablation antenna of the first embodiment consists of a triangular pyramid puncture head 1, a medium tube 2, a semi-rigid coaxial cable 3, an outer guide sleeve 4, a thin Wall PTFE tube 6, steel wire clamp 5, coil spring 7, handle tube 8, handle seat 9, radio frequency connector 10. The inner conductor of the semi-rigid coaxial cable 3 is installed in the blind hole of the cylinder at the tail of the triangular pyramid piercing head 1, and is fixed by welding and riveting; The inner hole at the front end of the outer guide sleeve 4 is fitted on the outer circle of the shoulder at the end of the medium tube 2, and the center hole is fitted on the semi-rigid coaxial cable 3, so that the two are in contact with each other. The parts are fixed by air-tight welding. The outer jacket of the semi-rigid coaxial cable 3 is provided with a coil spring 7 extending to the tail of the antenna, and the coil spring 7 and the semi-rigid coaxial cable 3 are loosely fitted. The tail of the outer guide sleeve 2 is provided with an axial groove, and the steel wire at the front end of the coil spring 7 is embedded in the axial groove for fixing, and is riveted by mechanical force and fixed with solder, so that the outer guide sleeve and the coil spring are formed. Tighten the connection. The thin-walled PTFE tube 6 is sheathed outside the coil spring 7 and the outer guide sleeve 4 , and its front end is fixed with the outer guide sleeve 4 . Specifically, the outer surface of the outer guide sleeve 4 is provided with an annular groove, and the front end of the thin-walled PTFE tube 6 is clamped into the annular groove through the steel wire clamp 5 to realize the fixation of the thin-walled PTFE tube 6 .
本实施例天线前端结构的装配流程如下：The assembly process of the antenna front-end structure in this embodiment is as follows:
首先，将半刚同轴电缆3的内导体装入三棱锥形穿刺头1尾部圆柱体的盲孔中，采用焊接并辅以压铆固定。然后，将介质管2装套在穿刺辐射头1尾部的圆柱体上，配合表面可涂粘接剂以固定,将外导套4装套在介质管2尾部的台肩外圆上，配合表面可涂粘接剂以固定,同时外导套4的中心孔也装套在半刚同轴电缆3的外导体表面上，对其二者接触部位采用气密性焊接固定。至此，即完成了本实施例前端辐射电磁波的场源结构之装配与组焊。First, put the inner conductor of the semi-rigid coaxial cable 3 into the blind hole of the tail cylinder of the triangular pyramid piercing head 1, and fix it by welding and riveting. Then, put the medium tube 2 on the cylinder at the tail of the puncture radiation head 1, and the mating surface can be coated with adhesive to fix it, and put the outer guide sleeve 4 on the outer circle of the shoulder at the tail of the medium tube 2, and the mating surface Adhesive can be applied to fix it, and at the same time, the center hole of the outer guide sleeve 4 is also sleeved on the surface of the outer conductor of the semi-rigid coaxial cable 3, and the contact parts of the two are fixed by air-tight welding. So far, the assembly and welding of the field source structure for radiating electromagnetic waves at the front end of this embodiment are completed.
接着，将螺旋弹簧7沿着半刚同轴电缆3的尾部装套并抵到外导套4的尾端，将螺旋弹簧7端面钢丝弯成90°，然后将其钢丝卡入外导套4台肩外圆表面的轴向沟槽内，并施以机械力铆压再辅以焊接固定在外导套上。注意：螺旋弹簧7长度应比半刚同轴电缆3长度要短10-15毫米，以不干涉天线体的自由弯曲。Next, wrap the coil spring 7 along the tail of the semi-rigid coaxial cable 3 and push it to the tail end of the outer guide sleeve 4, bend the steel wire of the end face of the coil spring 7 into 90°, and then clamp the steel wire into the outer guide sleeve 4 In the axial groove on the outer surface of the shoulder, it is fixed on the outer guide sleeve by mechanical force riveting and then supplemented by welding. Note: The length of the coil spring 7 should be 10-15mm shorter than the length of the semi-rigid coaxial cable 3 so as not to interfere with the free bending of the antenna body.
最后，将薄壁四氟管6沿螺旋弹簧7尾部装套至外导套4的台肩外圆上，然后用钢丝卡箍5对位于外导套4的径向环槽将薄壁四氟管6牢牢地卡在径向环槽内。注意：薄壁四氟管长度应比半刚同轴电缆3长度也要短10-15毫米，以不干涉天线体的自由弯曲。Finally, fit the thin-walled PTFE tube 6 to the outer circle of the shoulder of the outer guide sleeve 4 along the tail of the coil spring 7, and then use the wire clamp 5 to align the thin-walled PTFE with the radial groove located on the outer guide sleeve 4. Tube 6 is firmly snapped into the radial ring groove. Note: The length of the thin-walled PTFE tube should also be 10-15 mm shorter than the length of the semi-rigid coaxial cable 3, so as not to interfere with the free bending of the antenna body.
至此，完成高性能半刚穿刺型微波消融天线前端零件的装配。So far, the assembly of the front-end parts of the high-performance semi-rigid puncture microwave ablation antenna is completed.
本实施例天线尾部结构的装配流程如下：The assembly process of the antenna tail structure in this embodiment is as follows:
首先，将半刚同轴电缆3的内、外导体分别于射频连接器10的内、外导体焊接牢固，不得短路，再完成射频连接器10座体焊接。First, the inner and outer conductors of the semi-rigid coaxial cable 3 are respectively welded to the inner and outer conductors of the RF connector 10 firmly without short circuit, and then the base body of the RF connector 10 is welded.
接着，将手柄座9装套于射频连接器10座体外圆，并粘接牢固。Next, the handle base 9 is sleeved on the outer circumference of the radio frequency connector 10 base, and is firmly bonded.
最后，将手柄管8沿天线体（穿刺头）前端装套与手柄座9子口对位粘接牢固。Finally, the handle tube 8 is fitted along the front end of the antenna body (puncturing head) and is firmly bonded to the sub-port of the handle base 9 in alignment.
至此完成本发明高性能半刚穿刺型微波消融天线的实施例一之装配，就其重要微波性能检测和负载试验的结果如下：So far, the assembly of Embodiment 1 of the high-performance semi-rigid puncture microwave ablation antenna of the present invention has been completed, and the results of its important microwave performance detection and load test are as follows:
1、用矢量网络分析仪测试，本发明实施例样件在空载状态下的电压驻波比为2.65＜3.0（部颁标准）；在负载状态下的电压驻波比为1.35＜1.5（部颁标准）。1. Tested with a vector network analyzer, the voltage standing wave ratio of the sample of the present invention under no-load state is 2.65 < 3.0 (Ministry standard); standard).
2、在微波热凝离体猪肝试验中，当热凝范围为 3.0 X 2.0公分时，本发明实施例样件的天线体外表面温度不高于45℃。2. In the microwave thermal coagulation in vitro pig liver test, when the thermal coagulation range is 3.0 × 2.0 cm, the external surface temperature of the antenna of the sample of the embodiment of the present invention is not higher than 45°C.
通过检测性能指标与试验数据证明：本发明能够安全有效地地适用于在“高清晰内窥镜系统”引导下，实施可视化的无创伤性或微创伤性的实体肿瘤微波介入治疗。The detection performance index and the test data prove that the present invention can be safely and effectively applied to the visible non-invasive or micro-invasive microwave interventional treatment of solid tumors under the guidance of the "high-definition endoscope system".
除上述实施例外，本发明还可以有其他实施方式。凡采用等同替换或等效变换形成的技术方案，均落在本发明权利要求的保护范围。In addition to the above-described embodiments, the present invention may also have other embodiments. All technical solutions formed by equivalent replacement or equivalent transformation fall within the protection scope of the claims of the present invention.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910322654.9ACN109938832A (en) | 2019-04-22 | 2019-04-22 | A high-performance semi-rigid puncture microwave ablation antenna |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910322654.9ACN109938832A (en) | 2019-04-22 | 2019-04-22 | A high-performance semi-rigid puncture microwave ablation antenna |
| Publication Number | Publication Date |
|---|---|
| CN109938832Atrue CN109938832A (en) | 2019-06-28 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910322654.9APendingCN109938832A (en) | 2019-04-22 | 2019-04-22 | A high-performance semi-rigid puncture microwave ablation antenna |
| Country | Link |
|---|---|
| CN (1) | CN109938832A (en) |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2101501U (en)* | 1991-08-09 | 1992-04-15 | 上海长海医院 | 2450 mhz microwave aerial for heating therapy |
| US5344441A (en)* | 1991-07-03 | 1994-09-06 | Volker Gronauer | Antenna arrangement with supply cable for medical applications |
| US20060259024A1 (en)* | 2005-05-10 | 2006-11-16 | Roman Turovskiy | Reinforced high strength microwave antenna |
| CN102903447A (en)* | 2012-11-08 | 2013-01-30 | 焦作市宝丰电缆有限公司 | 6-35 KV mechanical impact resistance three-core fireproof power cable |
| CN202871367U (en)* | 2012-10-18 | 2013-04-10 | 常州市新东方电缆有限公司 | Fireproof single-core medium-voltage cable |
| CN103340684A (en)* | 2013-03-27 | 2013-10-09 | 杨兴瑞 | Semi-rigid water-cooling microwave ablation antenna |
| CN206273253U (en)* | 2016-08-03 | 2017-06-23 | 南京微创医学科技股份有限公司 | One kind can cross microwave melt needle under seal wire Non-water-cooled scope |
| CN108135656A (en)* | 2015-10-19 | 2018-06-08 | 科瑞欧医疗有限公司 | Electrosurgical instrument |
| CN108992166A (en)* | 2018-05-25 | 2018-12-14 | 南京亿高微波系统工程有限公司 | A kind of spiral type micro-wave temperature control varicose treatment conduit |
| CN109259857A (en)* | 2018-10-22 | 2019-01-25 | 广东百德医疗有限公司 | One kind semi-rigid penetration type water cooling Microwave Coagulation Therapy instrument under endoscope guidance |
| CN210095903U (en)* | 2019-04-22 | 2020-02-21 | 南京长城医疗设备有限公司 | High-performance semi-rigid puncture type microwave ablation antenna |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5344441A (en)* | 1991-07-03 | 1994-09-06 | Volker Gronauer | Antenna arrangement with supply cable for medical applications |
| CN2101501U (en)* | 1991-08-09 | 1992-04-15 | 上海长海医院 | 2450 mhz microwave aerial for heating therapy |
| US20060259024A1 (en)* | 2005-05-10 | 2006-11-16 | Roman Turovskiy | Reinforced high strength microwave antenna |
| CN202871367U (en)* | 2012-10-18 | 2013-04-10 | 常州市新东方电缆有限公司 | Fireproof single-core medium-voltage cable |
| CN102903447A (en)* | 2012-11-08 | 2013-01-30 | 焦作市宝丰电缆有限公司 | 6-35 KV mechanical impact resistance three-core fireproof power cable |
| CN103340684A (en)* | 2013-03-27 | 2013-10-09 | 杨兴瑞 | Semi-rigid water-cooling microwave ablation antenna |
| CN108135656A (en)* | 2015-10-19 | 2018-06-08 | 科瑞欧医疗有限公司 | Electrosurgical instrument |
| CN206273253U (en)* | 2016-08-03 | 2017-06-23 | 南京微创医学科技股份有限公司 | One kind can cross microwave melt needle under seal wire Non-water-cooled scope |
| CN108992166A (en)* | 2018-05-25 | 2018-12-14 | 南京亿高微波系统工程有限公司 | A kind of spiral type micro-wave temperature control varicose treatment conduit |
| CN109259857A (en)* | 2018-10-22 | 2019-01-25 | 广东百德医疗有限公司 | One kind semi-rigid penetration type water cooling Microwave Coagulation Therapy instrument under endoscope guidance |
| CN210095903U (en)* | 2019-04-22 | 2020-02-21 | 南京长城医疗设备有限公司 | High-performance semi-rigid puncture type microwave ablation antenna |
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| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication | Application publication date:20190628 |