A kind of glioma diagnosing and treating apparatusTechnical field
The invention belongs to medical instruments fields, more particularly, to a kind of glioma diagnosing and treating apparatus.
Background technique
Glioma is brain and spinal cord spongiocyte source, the most common primary pernicious intracranial tumour.For brain glueThe treatment method of matter tumor is usually perform the operation excision plus postoperative chemotherapy, radiotherapy.But glioma, especially High Grade Gliomas are notIt recurs avoidablely, poor prognosis.Therefore, it is necessary to one kind to be applied multiple times after surgery, and lesser to patient traumaClinics recur the state of an illness to treat glioma.
Photodynamic therapy is a kind of emerging tumor therapeuticing method, and principle is that specific sensitising agent is injected with human bodyInterior, in certain time window, at this moment photosensitizer can be shone in the enrichment of tumor tissue specificity using the light source of specific wavelengthIt penetrates, photosensitization chemical reaction can be generated, generate bio-toxicity substance, kill tumor tissues.
But conventional photodynamic therapy needs to expose tissue, it is difficult to be applied multiple times glioma is postoperative.Chinese patent2011101389070 (application numbers) propose a kind of glioma treatment device that can be fixed on skull, can be to avoid lightExposure brain tissue in dynamic therapy reduces the damage of patient, and infection rate is low.But the apparatus structure is complicated, and volume is larger, uncomfortableFor being chronically implanted on head, it is difficult to be used for multiple times for a long time；Irradiation end is fixed, it is difficult to be realized to different parts tumor tissuesPrecisely irradiation；It is not suitable for deep tumor light power irradiation treatment；Use process is cumbersome, complicated, and the practicability is poor.In addition, the dressIt sets and is simply possible to use in treatment, need to rely on imaging methods and judge that brain tumor recurs the state of an illness.
Summary of the invention
The purpose of the present invention is to provide a kind of glioma diagnosing and treating apparatus, and mainly solving existing apparatus, structure is complicated, noSuitable for being chronically implanted on head, being difficult to the problem of being used for multiple times for a long time.
To achieve the above object, the technical solution used in the present invention is:
A kind of glioma diagnosing and treating apparatus, it is characterised in that: including the light power irradiation conduit being used in conjunction with each other and plantEnter conduit.
Further, the smooth power irradiation conduit includes irradiation catheter tube, and the irradiation catheter tube is built-in with lightPower irradiation optical fiber；One end of the smooth power irradiation optical fiber is located at the lower end surface of irradiation catheter tube, and the other end is connected with lightPower interface.
Further, the irradiation end of the irradiation catheter tube is additionally provided with image-forming block.
Further, the irradiation end of the irradiation catheter tube is additionally provided with lighting source.
Further, the lighting source includes lighting fiber, and one end of the lighting fiber is located at irradiation catheter tubeLower end surface, the other end is connected with lighting interface.
Further, the irradiation catheter tube lower part is active bending portion.
Further, the active bending portion is fin tube structure.
Further, the irradiation catheter tube top is handle, is additionally provided on the handle for controlling active bendingThe regulating mechanism in portion.
Further, the regulating mechanism includes two angulation knobs, positive and negative on each angulation knob to be wound with two and leadDraw silk, the end of the traction fiber is connect with the edge of the lower end surface of irradiation catheter tube, and four traction fibers are along irradiation catheter tubeBody lower end surface even circumferential arranges that two traction fibers on same angulation knob are positioned opposite.
Further, the implantation catheter is up big and down small flared structure, and upper end is equipped with catheter stopper.
The invention has the benefit that
(1) it is directed to the characteristic easy to recur of glioma, the present invention is led using split type light power irradiation conduit and implantationPipe, the two structure is simple, is that a kind of can extract the needle of the Micro trauma that postoperative patient head is long-term, is applied multiple times in gliomaTo the diagnoses and treatment instrument of tumor recurrence, diagnosis is sensitive, quick, and treatment is accurate.Human body implant part structure of the invention is simple,It is small in size, it can be chronically implanted, and will not influence patient's appearance and daily life.
(2) built in video of the present invention shoots structure, cooperates lighting source, can it is simple, quick, sensitively to patient's brain glueMatter tumor recurrence is diagnosed, and can implement photodynamic therapy, and patient's damage is small.The present invention may be implemented to recurrence portionThe sensitive diagnosis of position and precisely treatment, improve patients ' recovery effect；Universality is high, all suitable to the glioma illness of different depthWith；It is easy to operate, practical.
(3) present invention is provided with active bending portion, and when treatment can precisely be directed at irradiation to tumor tissues, to surface layer and depthPortion's glioma is all suitable for, and structure is simple, using simple.
(4) the configuration of the present invention is simple, at low cost, infection risk when being treated for reduction patient, light power photograph of the inventionPenetrating conduit can be disposable component.
Detailed description of the invention
Fig. 1 is overall schematic of the invention.
Fig. 2 is lower end surface (irradiation end) schematic diagram for irradiating catheter tube.
Fig. 3 be install traction fiber before and after active bending portion schematic diagram (in figure A for installation traction fiber before, B be installation tractionAfter silk).
Fig. 4 is the schematic diagram when present invention uses.
In figure: 1, implantation catheter tube body, 2, catheter stopper, 3, irradiation catheter tube, 4, active bending portion, 5, handle, 6, photographBright interface, 7, light power interface, 8, video interface, 9, angulation knob, 10, lighting fiber, 11, light power irradiation optical fiber, 12, atAs component, 13, traction fiber, 14, fin, 15, tumour chamber.
Specific embodiment
For a better understanding of the present invention, technical solution of the present invention is done further below with reference to embodiment and attached drawingExplanation.
A kind of glioma diagnosing and treating apparatus, including the light power irradiation conduit being used in conjunction with each other and implantation catheter.
As shown in Figure 1, wherein the implantation catheter includes implantation catheter tube body 1, the implantation catheter tube body 1 be it is upper it is big underSmall flared structure, upper end are equipped with catheter stopper 2.
The smooth power irradiation conduit includes irradiation catheter tube 3, and 3 top of irradiation catheter tube is handle 5, describedActive bending portion 4 is fin tube structure.
5 top of handle is equipped with light power interface 7, lighting interface 6 and video interface 8, in the irradiation catheter tube 3Be equipped with light power irradiation optical fiber 11 and lighting fiber 10, the smooth power irradiation optical fiber 11 and lighting fiber 10 be plastic optical fiber orThe lower end of glass optical fiber or silica fibre, the smooth power irradiation optical fiber 11 and lighting fiber 10 is respectively positioned on irradiation catheter tube 3Lower end surface on, the upper end of the smooth power irradiation optical fiber 11 and lighting fiber 10 respectively with light power interface 7 and lighting interface 6Connection, the lighting interface 6 are connect with lighting for medical use light source, and the smooth power interface 7 is connect with clinical light power light source.InstituteStating image-forming block 12 is image transmission optical fibre or miniature electronic image-forming component, and the image-forming block 12 is also mounted at irradiation catheter tubeOn 3 lower end surface, and it is connect by video interface 8 with exterior display device.
The implantation catheter tube body 1, catheter stopper 2 and irradiation catheter tube 3 are by silica gel, polyurethane or other biological compatibilityIt is good that there is high molecular material flexible to be made.There are many length scales for the implantation catheter tube body 1 and irradiation catheter tube 3Lattice can be selected according to knub position depth.Volume can be increased inside the implantation catheter tube body 1 and irradiation catheter tube 3To enhance tube body supportive, mesh grid is the compatible metal net of nuclear-magnetism for knitmesh.The catheter stopper 2 and implantation catheter tube body 1It closed can plug together.
The regulating mechanism for controlling active bending portion 4 is additionally provided on the handle 5, the regulating mechanism includes two anglesKnob 9 is spent, it is positive and negative on each angulation knob 9 to be wound with two traction fibers 13, the end of the traction fiber 13 and irradiation catheter tubeThe edge of the lower end surface of body 3 connects, and four traction fibers 13 are along irradiation 3 lower end surface even circumferential of catheter tube arrangement, same angleTwo traction fibers 13 on knob 9 are positioned opposite；The lower end of one control irradiation catheter tube 3 of angulation knob 9 is forward and backwardOr left and right directions turns to (as shown in Figure 3).The traction fiber 13 runs in the guide irradiation 3 outer wall of catheter tube (packet with free stateInclude the fin 14 that free state runs through active bending portion 4) in, described 13 one end of traction fiber is fixed on irradiation catheter tube 3The edge of lower end surface, one end are fixed on the angulation knob 9 on handle, drive traction fiber 13, traction by rotation angulation knob 9Silk 13 is pullled so that active bending portion 4 is bent towards the direction of needs.The traction fiber 13 can be stainless steel wire or titanium-nickel wire,Crooked position front end for fixed traction silk 13 is metal or rigid plastic components.
Application method of the invention:
(1) after operation extracts glioma, the lower end of implantation catheter is placed in tumour chamber 15, as shown in figure 4, describedImplantation catheter tube body 1 is implanted in brain and fixes at operative region skull, and only catheter stopper 2 is exposed under scalp.
(2) surgical removal Puncture in Brain Glioma Patients carries out recurrence diagnosis using diagnosing and treating apparatus of the present invention in checkProcess is: intravenous administration clinic glioma mark fluorescent agent, under aseptic operation environment, opens catheter stopper 2, will irradiateCatheter tube 3 is inserted into the inner hole of implantation catheter tube body 1, and then enters tumour chamber 15.Lighting fiber 10 shines to tumour chamber15 carry out diagnosis illumination, issue fluorescence with the agent of glioma mark fluorescent by the way that excitation is clinical, and with image-forming block 12 in real time atAs judging glioma recurrence.Cooperate doctor's operation that entire tumor chamber may be implemented by operating the angulation knob 9Diagnostic observation, it is easy to operate, detection it is sensitive.
(3) when discovery is there are the glioma recurrence state of an illness and determines treatment, intravenous administration clinic glioma lightDynamic therapy photosensitizer cooperates doctor's operation that will irradiate catheter tube under the guide of image-forming block 12 by work angle knob 93 lower end of body is close to alignment recurrent tumor tissue, and light power irradiation optical fiber 11 is connect with clinic with photodynamic therapy light source, to recurrenceTumor tissues carry out light power irradiation treatment.
(4) after treatment end, irradiation catheter tube 3 is extracted, catheter stopper 2 is stoppered again, and do the anti-infective place of disinfectionReason.
Described above is only Application Example of the invention, cannot limit the right model of the present invention with this certainlyIt encloses, therefore according to equivalence changes made by scope of the present invention patent, still belongs to protection scope of the present invention.