技术领域technical field
本发明涉及一种眼用镜片材料及应用该眼用镜片材料制得的眼用镜片，尤其涉及一种硬性透氧性眼用镜片材料及应用该硬性透氧性眼用镜片材料制得的硬性透氧性眼用镜片。The invention relates to an ophthalmic lens material and an ophthalmic lens prepared by using the ophthalmic lens material, in particular to a rigid oxygen-permeable ophthalmic lens material and a rigid oxygen-permeable ophthalmic lens material prepared by using the rigid oxygen-permeable ophthalmic lens material Oxygen permeable ophthalmic lenses.
背景技术Background technique
近年来，随着近视人群的数量越来越多，隐形眼镜因其便携、美观的特性而被广泛使用，此外，对于高度近视者一般会通过将透明晶(晶状体)全摘除，然后植入眼内镜片(人工晶状体等)，以使高度近视者可以看清物体。因隐形眼镜、眼内镜片等眼用镜片直接覆盖在角膜的表面，若眼用镜片的透氧性不高，很容易使得角膜缺氧，引起角膜病变。In recent years, with the increasing number of people with myopia, contact lenses are widely used because of their portability and beauty. In addition, for people with high myopia, the clear lens (lens) is generally removed and then implanted into the eye. Inner lenses (intraocular lenses, etc.) to allow people with high myopia to see objects clearly. Because contact lenses, intraocular lenses and other ophthalmic lenses directly cover the surface of the cornea, if the oxygen permeability of the ophthalmic lenses is not high, it is easy to make the cornea hypoxia and cause corneal lesions.
此外，在角膜矫正术中，患者需要在夜间佩戴角膜塑型片，该角膜塑型片为硬性透氧性眼用镜片(硬性透氧性角膜接触镜)，佩戴过程中无法眨眼，使得镜片与角膜之间泪液交换不足，很容易造成角膜缺氧，严重影响角膜的健康。In addition, in orthokeratology, patients need to wear orthokeratology lenses at night, which are hard oxygen-permeable ophthalmic lenses (hard oxygen-permeable contact lenses). Insufficient tear exchange between the corneas can easily cause corneal hypoxia, which seriously affects the health of the cornea.
发明内容SUMMARY OF THE INVENTION
有鉴于此，有必要提供一种新的硬性透氧性眼用镜片材料，以解决上述问题。In view of this, it is necessary to provide a new rigid oxygen-permeable ophthalmic lens material to solve the above problems.
另，还有必要提供一种应用所述硬性透氧性眼用镜片材料制得的硬性透氧性眼用镜片。In addition, it is also necessary to provide a rigid oxygen-permeable ophthalmic lens prepared by using the rigid oxygen-permeable ophthalmic lens material.
一种硬性透氧性眼用镜片材料，其包含硅树脂、含氟化合物、丙烯酸酯单体及热引发剂。A rigid oxygen-permeable ophthalmic lens material comprises silicone resin, fluorine-containing compound, acrylate monomer and thermal initiator.
一种硬性透氧性眼用镜片，该硬性透氧性眼用镜片由硬性透氧性眼用镜片材料制得，该硬性透氧性眼用镜片材料包含硅树脂、含氟化合物、丙烯酸酯单体及热引发剂。A rigid oxygen-permeable ophthalmic lens, the rigid oxygen-permeable ophthalmic lens is made of a rigid oxygen-permeable ophthalmic lens material, the rigid oxygen-permeable ophthalmic lens material comprises silicone resin, fluorine-containing compound, acrylate monolayer body and thermal initiators.
本发明的硬性透氧性眼用镜片材料制得的硬性透氧性眼用镜片具有较高的透氧性，有利于使用者的角膜健康。该硬性透氧性眼用镜片还具有较高的透光性，便于使用者看清物体。The rigid oxygen-permeable ophthalmic lens made of the rigid oxygen-permeable ophthalmic lens material of the present invention has high oxygen permeability, which is beneficial to the cornea health of the user. The rigid oxygen-permeable ophthalmic lens also has high light transmittance, which is convenient for users to see objects clearly.
具体实施方式Detailed ways
基于本发明中的实施方式，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施方式，都属于本发明保护的范围。Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
本文所使用的所有的技术和科学术语与属于本发明的技术领域的技术人员通常理解的含义相同。本文中在本发明的说明书中所使用的术语只是为了描述具体的实施方式的目的，不是旨在于限制本发明。All technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the technical field of the invention. The terms used herein in the description of the present invention are for the purpose of describing specific embodiments only, and are not intended to limit the present invention.
本发明较佳实施方式提供一种硬性透氧性眼用镜片材料，其用于制备硬性透氧性眼用镜片。该硬性透氧性眼用镜片材料包含硅树脂、含氟化合物、丙烯酸酯单体及热引发剂。A preferred embodiment of the present invention provides a rigid oxygen-permeable ophthalmic lens material, which is used for preparing the rigid oxygen-permeable ophthalmic lens. The hard oxygen-permeable ophthalmic lens material includes silicone resin, fluorine-containing compound, acrylate monomer and thermal initiator.
所述硬性透氧性眼用镜片材料中，所述硅树脂的质量百分含量为5.35％～62.96％，所述含氟化合物的质量百分含量为 4.35％～28.95％，所述丙烯酸酯单体的质量百分含量为 32.08％～90.03％。In the hard oxygen-permeable ophthalmic lens material, the mass percentage content of the silicone resin is 5.35% to 62.96%, the mass percentage content of the fluorine-containing compound is 4.35% to 28.95%, and the acrylate monolayer The mass percentage of the body is 32.08% to 90.03%.
所述硬性透氧性眼用镜片材料中的热引发剂的含量没有限制，只要所述硬性透氧性眼用镜片材料中添加有热引发剂，在加热的时候，该热引发剂即可引发所述硅树脂、含氟化合物及丙烯酸酯单体发生聚合反应。The content of the thermal initiator in the hard oxygen-permeable ophthalmic lens material is not limited, as long as the thermal initiator is added to the hard oxygen-permeable ophthalmic lens material, the thermal initiator can be initiated when heated. The silicone resin, the fluorine-containing compound and the acrylate monomer undergo a polymerization reaction.
所述硅树脂包括但不限于四乙氧基硅烷(tetraethoxysilane， TEOS)、甲基三甲氧基硅烷(methyl-trimethoxysilane，MTMS)、及 3-(三甲氧基硅基)丙基甲基丙烯酸酯(3-(trimethoxysilyl)propyl methacrylate，MPTMS)中的一种或几种。The silicone resins include but are not limited to tetraethoxysilane (TEOS), methyl-trimethoxysilane (MTMS), and 3-(trimethoxysilyl)propyl methacrylate ( One or more of 3-(trimethoxysilyl)propyl methacrylate, MPTMS).
所述含氟化合物包括但不限于丙烯酸全氟庚酯 (perfluorohexylethylacrylate，PFHEA)、丙烯酸八氟戊酯 (Octafluoropentyl acrylate，OFPA)、及丙烯酸十二氟庚酯 (Dodecafluoroheptyl acrylate，DFHA)中的一种或几种。The fluorine-containing compound includes, but is not limited to, one of perfluorohexylethylacrylate (PFHEA), Octafluoropentylacrylate (OFPA), and Dodecafluoroheptylacrylate (DFHA). several.
所述丙烯酸酯单体包括但不限于甲基丙烯酸甲酯(methyl methacrylate，MMA)、甲基丙烯酸(methacrylic acid，MAA)、及甲基丙烯酸2-羟基乙酯(2-Hydroxyethylmethacrylate，HEMA)中的一种或几种。该丙烯酸酯单体在热引发剂的作用下可以聚合形成高分子聚合物。The acrylate monomers include, but are not limited to, methyl methacrylate (MMA), methacrylic acid (MAA), and 2-hydroxyethyl methacrylate (2-Hydroxyethylmethacrylate, HEMA). one or more. The acrylate monomer can be polymerized to form a high molecular polymer under the action of a thermal initiator.
所述热引发剂包括但不限于偶氮二异丁腈(AIBN)、4,4'-偶氮双(4-氰基戊酸)(ACVA)、及2,2'-氮杂双(2-咪唑啉)二盐酸盐(AIP) 中的一种或两种。The thermal initiators include, but are not limited to, azobisisobutyronitrile (AIBN), 4,4'-azobis(4-cyanovaleric acid) (ACVA), and 2,2'-azabi(2 - one or both of imidazoline) dihydrochloride (AIP).
一种硬性透氧性眼用镜片，其可为隐形眼镜、眼内镜片(AIOL) 等，该眼内镜片可为人工晶状体(IOLs)等。该硬性透氧性眼用镜片由上述硬性透氧性眼用镜片材料制得。A rigid oxygen-permeable ophthalmic lens, which can be a contact lens, an intraocular lens (AIOL), etc., and the intraocular lens can be an intraocular lens (IOLs) and the like. The rigid oxygen-permeable ophthalmic lens is prepared from the above-mentioned rigid oxygen-permeable ophthalmic lens material.
一种硬性透氧性眼用镜片的制造方法，其包括以下步骤：A method for manufacturing a rigid oxygen-permeable ophthalmic lens, comprising the following steps:
步骤S1，提供硅树脂、含氟化合物、丙烯酸酯单体及热引发剂，将该硅树脂、该含氟化合物、该丙烯酸酯单体及热引发剂按照预定的比例混合均匀，得到混合溶液。Step S1, providing silicone resin, fluorine-containing compound, acrylate monomer and thermal initiator, and uniformly mixing the silicone resin, fluorine-containing compound, acrylate monomer and thermal initiator according to a predetermined ratio to obtain a mixed solution.
步骤S2，提供一眼用镜片模具，将上述混合溶液置于眼用镜片模具中，在一定温度下烘烤一段时间，使所述硅树脂、含氟化合物、丙烯酸酯单体在热引发剂的作用下发生聚合反应，压合，得到硬性透氧性眼用镜片片材。Step S2, providing an ophthalmic lens mold, placing the above mixed solution in the ophthalmic lens mold, and baking at a certain temperature for a period of time, so that the silicone resin, the fluorine-containing compound, and the acrylate monomer can act as a thermal initiator. A polymerization reaction occurs under the following conditions, and the sheets are pressed together to obtain a rigid oxygen-permeable ophthalmic lens sheet.
所述烘烤的温度可以为65～95℃。所述烘烤时间可以为0.5～12 小时。The baking temperature may be 65-95°C. The baking time may be 0.5-12 hours.
步骤S3，对所述硬性透氧性眼用镜片片材的表面进行切削加工，以得到硬性透氧性眼用镜片。Step S3, cutting the surface of the hard oxygen-permeable ophthalmic lens sheet to obtain a hard oxygen-permeable ophthalmic lens.
所述硬性透氧性眼用镜片材料在加热时，硅树脂、含氟化合物及丙烯酸酯单体在热引发剂的作用下会发生聚合反应，形成包括多条链的高分子聚合物。因所述硬性透氧性眼用镜片材料包括硅树脂及含氟化合物，因此，所述硬性透氧性眼用镜片材料含有硅原子及氟原子，该硅原子及氟原子可以使所形成的高分子聚合物的链与链之间有较大的空隙，如此可以增加氧气分子在高分子聚合物中的穿透能力，使得由所述硬性透氧性眼用镜片材料制得的硬性透氧性眼用镜片具有高透氧性。When the rigid oxygen-permeable ophthalmic lens material is heated, the silicone resin, the fluorine-containing compound and the acrylate monomer will undergo a polymerization reaction under the action of the thermal initiator to form a high molecular polymer including multiple chains. Because the hard oxygen-permeable ophthalmic lens material includes silicone resin and a fluorine-containing compound, the hard oxygen-permeable ophthalmic lens material contains silicon atoms and fluorine atoms, and the silicon atoms and fluorine atoms can make the formed high There are large gaps between the chains of the molecular polymer, which can increase the penetrating ability of oxygen molecules in the high molecular polymer, so that the rigid oxygen-permeable ophthalmic lens material made of the rigid oxygen-permeable ophthalmic lens material can be Ophthalmic lenses have high oxygen permeability.
下面通过实施例来对本发明进行具体说明。The present invention will be specifically described below by way of examples.
实施例1Example 1
本实施例的硬性透氧性眼用镜片材料包含PFHEA、MPTMS、MMA、AIBN、及TEOS。The rigid oxygen-permeable ophthalmic lens material of this embodiment includes PFHEA, MPTMS, MMA, AIBN, and TEOS.
其中，PFHEA的质量百分含量为6.67％，MPTMS的质量百分含量为13.33％，MMA的质量百分含量为46.67％，AIBN的质量百分含量为0.82％，TEOS的质量百分含量为32.51％。Among them, the mass percentage of PFHEA is 6.67%, the mass percentage of MPTMS is 13.33%, the mass percentage of MMA is 46.67%, the mass percentage of AIBN is 0.82%, and the mass percentage of TEOS is 32.51% %.
本实施例的硬性透氧性眼用镜片通过以下步骤制得：将上述硬性透氧性眼用镜片材料混合均匀，得到混合溶液；将上述混合溶液置于眼用镜片模具中，在87℃下烘烤5个小时，压合，得到硬性透氧性眼用镜片片材；对该硬性透氧性眼用镜片片材的表面进行切削加工，得到硬性透氧性眼用镜片。The rigid oxygen-permeable ophthalmic lens of the present embodiment is prepared by the following steps: mixing the above-mentioned rigid oxygen-permeable ophthalmic lens material uniformly to obtain a mixed solution; placing the above-mentioned mixed solution in an ophthalmic lens mold, at 87° C. Baking for 5 hours and pressing to obtain a rigid oxygen-permeable ophthalmic lens sheet; cutting the surface of the rigid oxygen-permeable ophthalmic lens sheet to obtain a rigid oxygen-permeable ophthalmic lens.
本实施例的硬性透氧性眼用镜片的透光率为99.5％。The light transmittance of the rigid oxygen-permeable ophthalmic lens of this example was 99.5%.
本实施例的硬性透氧性眼用镜片的透氧值DK为150。The oxygen permeability value DK of the rigid oxygen-permeable ophthalmic lens of this embodiment is 150.
实施例2Example 2
本实施例的硬性透氧性眼用镜片材料包含PFHEA、MPTMS、 HEMA、AIBN、及TEOS。The rigid oxygen-permeable ophthalmic lens material of this embodiment includes PFHEA, MPTMS, HEMA, AIBN, and TEOS.
其中，PFHEA的质量百分含量为13.32％，MPTMS的质量百分含量为13.33％，HEMA的质量百分含量为45.28％，AIBN的质量百分含量为0.85％，TEOS的质量百分含量为27.22％。Among them, the mass percentage of PFHEA is 13.32%, the mass percentage of MPTMS is 13.33%, the mass percentage of HEMA is 45.28%, the mass percentage of AIBN is 0.85%, and the mass percentage of TEOS is 27.22 %.
本实施例的硬性透氧性眼用镜片通过以下步骤制得：将上述硬性透氧性眼用镜片材料混合均匀，得到混合溶液；将上述混合溶液置于眼用镜片模具中，在90℃下烘烤8个小时，压合，得到硬性透氧性眼用镜片片材；对该硬性透氧性眼用镜片片材的表面进行切削加工，得到硬性透氧性眼用镜片。The rigid oxygen-permeable ophthalmic lens of the present embodiment is prepared by the following steps: mixing the above-mentioned rigid oxygen-permeable ophthalmic lens materials uniformly to obtain a mixed solution; placing the above-mentioned mixed solution in an ophthalmic lens mold, at 90° C. Baking for 8 hours and pressing to obtain a rigid oxygen-permeable ophthalmic lens sheet; cutting the surface of the rigid oxygen-permeable ophthalmic lens sheet to obtain a rigid oxygen-permeable ophthalmic lens.
本实施例的硬性透氧性眼用镜片的透光率为97％。The light transmittance of the rigid oxygen-permeable ophthalmic lens of this example was 97%.
本实施例的硬性透氧性眼用镜片的透氧值DK为160。The oxygen permeability value DK of the rigid oxygen-permeable ophthalmic lens of this embodiment is 160.
实施例3Example 3
本实施例的硬性透氧性眼用镜片材料包含PFHEA、MPTMS、 HEMA、MTMS、AIBN、及TEOS。The rigid oxygen-permeable ophthalmic lens material of this embodiment includes PFHEA, MPTMS, HEMA, MTMS, AIBN, and TEOS.
其中，PFHEA的质量百分含量为12.32％，MPTMS的质量百分含量为12.33％，HEMA的质量百分含量为43.85％，MTMS的质量百分含量为8.45％，AIBN的质量百分含量为0.85％，TEOS的质量百分含量为22.2％。Among them, the mass percentage of PFHEA is 12.32%, the mass percentage of MPTMS is 12.33%, the mass percentage of HEMA is 43.85%, the mass percentage of MTMS is 8.45%, and the mass percentage of AIBN is 0.85% %, the mass percentage of TEOS is 22.2%.
本实施例的硬性透氧性眼用镜片通过以下步骤制得：将上述硬性透氧性眼用镜片材料混合均匀，得到混合溶液；将上述混合溶液置于眼用镜片模具中，在90℃下烘烤8个小时，压合，得到硬性透氧性眼用镜片片材；对该硬性透氧性眼用镜片片材的表面进行切削加工，得到硬性透氧性眼用镜片。The rigid oxygen-permeable ophthalmic lens of the present embodiment is prepared by the following steps: mixing the above-mentioned rigid oxygen-permeable ophthalmic lens materials uniformly to obtain a mixed solution; placing the above-mentioned mixed solution in an ophthalmic lens mold, at 90° C. Baking for 8 hours and pressing to obtain a rigid oxygen-permeable ophthalmic lens sheet; cutting the surface of the rigid oxygen-permeable ophthalmic lens sheet to obtain a rigid oxygen-permeable ophthalmic lens.
本实施例的硬性透氧性眼用镜片的透光率为98％。The light transmittance of the rigid oxygen-permeable ophthalmic lens of this example is 98%.
本实施例的硬性透氧性眼用镜片的透氧值DK为150。The oxygen permeability value DK of the rigid oxygen-permeable ophthalmic lens of this embodiment is 150.
实施例4Example 4
本实施例的硬性透氧性眼用镜片材料包含OFPA、MPTMS、 MMA、MTMS、AIBN、及TEOS。The rigid oxygen-permeable ophthalmic lens material of this embodiment includes OFPA, MPTMS, MMA, MTMS, AIBN, and TEOS.
其中，OFPA的质量百分含量为13.42％，MPTMS的质量百分含量为13.51％，MMA的质量百分含量为40.69％，MTMS的质量百分含量为8.89％，AIBN的质量百分含量为0.9％，TEOS的质量百分含量为22.59％。Among them, the mass percentage of OFPA is 13.42%, the mass percentage of MPTMS is 13.51%, the mass percentage of MMA is 40.69%, the mass percentage of MTMS is 8.89%, and the mass percentage of AIBN is 0.9 %, the mass percentage of TEOS is 22.59%.
本实施例的硬性透氧性眼用镜片通过以下步骤制得：将上述硬性透氧性眼用镜片材料混合均匀，得到混合溶液；将上述混合溶液置于眼用镜片模具中，在90℃下烘烤8个小时，压合，得到硬性透氧性眼用镜片片材；对该硬性透氧性眼用镜片片材的表面进行切削加工，得到硬性透氧性眼用镜片。The rigid oxygen-permeable ophthalmic lens of the present embodiment is prepared by the following steps: mixing the above-mentioned rigid oxygen-permeable ophthalmic lens materials uniformly to obtain a mixed solution; placing the above-mentioned mixed solution in an ophthalmic lens mold, at 90° C. Baking for 8 hours and pressing to obtain a rigid oxygen-permeable ophthalmic lens sheet; cutting the surface of the rigid oxygen-permeable ophthalmic lens sheet to obtain a rigid oxygen-permeable ophthalmic lens.
本实施例的硬性透氧性眼用镜片的透光率为98％。The light transmittance of the rigid oxygen-permeable ophthalmic lens of this example is 98%.
本实施例的硬性透氧性眼用镜片的透氧值DK为180。The oxygen permeability value DK of the rigid oxygen-permeable ophthalmic lens of this embodiment is 180.
本发明的硬性透氧性眼用镜片材料制得的硬性透氧性眼用镜片具有较高的透氧性，有利于使用者的角膜健康。此外，该硬性透氧性眼用镜片还具有较高的透光性，便于使用者看清物体。The rigid oxygen-permeable ophthalmic lens made of the rigid oxygen-permeable ophthalmic lens material of the present invention has high oxygen permeability, which is beneficial to the cornea health of the user. In addition, the rigid oxygen-permeable ophthalmic lens also has high light transmittance, which is convenient for users to see objects clearly.
另外，以上所述，仅是本发明的较佳实施方式而已，并非对本发明任何形式上的限制，虽然本发明已将较佳实施方式揭露如上，但并非用以限定本发明，任何熟悉本专业的技术人员，在不脱离本发明技术方案范围内，当可利用上述揭示的技术内容做出些许更动或修饰为等同变化的等效实施方式，但凡是未脱离本发明技术方案内容，依据本发明的技术实质对以上实施方式所做的任何简单修改、等同变化与修饰，均仍属于本发明技术方案的范围内。In addition, the above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention in any form. Although the preferred embodiments of the present invention have been disclosed as above, they are not intended to limit the present invention. Those skilled in the art, without departing from the scope of the technical solution of the present invention, can make some changes or modifications to equivalent embodiments of equivalent changes by using the technical content disclosed above. Any simple modifications, equivalent changes and modifications made to the above embodiments by the technical essence of the invention still fall within the scope of the technical solutions of the present invention.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711045111.4ACN109725439A (en) | 2017-10-31 | 2017-10-31 | Hard oxygen permeable ophthalmic lens material and rigid oxygen permeable ophthalmic lens |
| Application Number | Priority Date | Filing Date | Title |
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| CN201711045111.4ACN109725439A (en) | 2017-10-31 | 2017-10-31 | Hard oxygen permeable ophthalmic lens material and rigid oxygen permeable ophthalmic lens |
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| CN109725439Atrue CN109725439A (en) | 2019-05-07 |
| Application Number | Title | Priority Date | Filing Date |
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| CN201711045111.4APendingCN109725439A (en) | 2017-10-31 | 2017-10-31 | Hard oxygen permeable ophthalmic lens material and rigid oxygen permeable ophthalmic lens |
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|---|---|---|---|---|
| CN114516942A (en)* | 2020-11-18 | 2022-05-20 | 亨泰光学股份有限公司 | Hard oxygen-permeable contact lens polymer material and polymerization method thereof |
| CN114516941A (en)* | 2020-11-18 | 2022-05-20 | 亨泰光学股份有限公司 | Polymerization method of polymer material for rigid oxygen permeable contact lens |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114516942A (en)* | 2020-11-18 | 2022-05-20 | 亨泰光学股份有限公司 | Hard oxygen-permeable contact lens polymer material and polymerization method thereof |
| CN114516941A (en)* | 2020-11-18 | 2022-05-20 | 亨泰光学股份有限公司 | Polymerization method of polymer material for rigid oxygen permeable contact lens |
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| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | Application publication date:20190507 |