技术领域Technical field
本发明涉及气溶胶发生器，特别是涉及一种微量粉尘气溶胶发生器。The present invention relates to an aerosol generator, in particular to a trace dust aerosol generator.
背景技术Background technique
吸入毒理学是研究可吸入物对机体毒作用发生、发展和消除的各种条件、规律和机制及对可吸入物进行危险性评价的一门科学。其专业研究内容主要有：空气中各种物质的理化特性；呼吸道的基础生物学；吸入物在体内的沉积和滞留及其与体内重要系统、器官间的相互作用；这些相互作用是如何导致疾病产生的。Inhalation toxicology is a science that studies the various conditions, laws and mechanisms of the occurrence, development and elimination of toxic effects of inhalable substances on the body and evaluates the risk of inhalable substances. Its professional research contents mainly include: the physical and chemical properties of various substances in the air; the basic biology of the respiratory tract; the deposition and retention of inhaled substances in the body and their interactions with important systems and organs in the body; how these interactions lead to diseases produced.
随着国际吸入毒理学研究日趋活跃，国内许多专家也充分认识到了吸入毒理学的重要意义。从研究的对象来看，有对人群的调查，也有对动物包括大鼠、小鼠、家兔、仓鼠等的研究；从研究的对象来看，都采用静式染毒；从研究的方法来看，有采用流行病学方法的，有利用超声诊断技术、同位素标记法、放射性气溶胶肺通气现象技术、荧光抗体技术等等；最长染毒时间有连续染毒8小时的，也有对接触5年以上人群进行流行病学调查的；有进行整体动物肺灌洗实验的，也有进行离体支气管肺泡灌洗液分析的；研究毒物的种类更达到包括氯气、沙漠尘、偏二甲基珙、柴油机排出物、汽车尾气颗粒物等几十余种；分析的指标有大鼠嗅觉粘膜毒性的酶组织化学改变、肺灌洗液中各种酶的变化、脾脏NK细胞和K细胞、肝微粒体钙泵、血小板等几十种。As international inhalation toxicology research becomes increasingly active, many domestic experts have fully realized the importance of inhalation toxicology. From the perspective of the research objects, there are surveys on the population, and there are also studies on animals including rats, mice, rabbits, hamsters, etc.; from the research objects, static poisoning is used; from the research methods Look, some use epidemiological methods, some use ultrasonic diagnostic technology, isotope labeling methods, radioactive aerosol lung ventilation technology, fluorescent antibody technology, etc.; the longest exposure time is 8 hours in a row, and some are exposed to the virus. Epidemiological surveys were conducted on people with more than 5 years of age; some conducted whole animal lung lavage experiments, and some conducted analysis of isolated bronchoalveolar lavage fluid; the types of poisons studied even included chlorine, desert dust, and metadimethylcondensate. , diesel engine exhaust, automobile exhaust particulate matter, etc.; the indicators analyzed include enzyme histochemical changes of rat olfactory mucosal toxicity, changes in various enzymes in lung lavage fluid, spleen NK cells and K cells, liver microsomes Calcium pumps, platelets, and dozens more.
现有的吸入毒理学研究中，研究的主要毒物之一为气溶胶，气溶胶包括粉尘气溶胶，现有的粉尘气溶胶发生器有旋转刷式的粉尘发生器（专利号201320577636.3）、齿带原理的粉尘发生器（专利号201110047698.9）和转盘式原理的粉尘发生器（专利号201010136283.4）等，对于中小量的粉末样品发生提出了较好的解决方案，但是针对微量样品，比如实验室的研究制备的微量生物蛋白干粉、昂贵的铂金粉、PM2.5粉尘等等，样品量常常小于1克甚至只有几毫克的量，目前技术的粉尘气溶胶发生器将无法连续稳定地将样品发生气溶胶。因此，如何针对微量粉尘来将其发生成气溶胶是气溶胶发生领域需要解决的问题。In the existing inhalation toxicology research, one of the main poisons studied is aerosol, which includes dust aerosol. The existing dust aerosol generators include rotating brush dust generator (Patent No. 201320577636.3), toothed belt The dust generator based on the principle (Patent No. 201110047698.9) and the dust generator based on the rotating disk principle (Patent No. 201010136283.4) have proposed better solutions for the generation of small and medium-sized powder samples, but for trace samples, such as laboratory research The prepared trace biological protein dry powder, expensive platinum powder, PM2.5 dust, etc. are often less than 1 gram or even only a few milligrams. The current technology dust aerosol generator will not be able to continuously and stably aerosolize the sample. . Therefore, how to generate trace amounts of dust into aerosols is a problem that needs to be solved in the field of aerosol generation.
发明内容Contents of the invention
针对现有技术存在的不足，本发明的目的在于提供一种可对微量粉尘进行操作、稳定性高的微量粉尘气溶胶发生器。In view of the shortcomings of the existing technology, the purpose of the present invention is to provide a trace dust aerosol generator that can operate on trace amounts of dust and has high stability.
为实现上述目的，本发明提供了如下技术方案： 一种微量粉尘气溶胶发生器， 包括控制组件和气溶胶发生组件，所述气溶胶发生组件包括震动喇叭，所述震动喇叭扩开口一侧可拆卸固定安装有震动片，所述震动片背向所述震动喇叭一侧设置有漩涡气流发生装置，所述漩涡气流发生装置背向所述震动片一侧连通有气溶胶发生舱；In order to achieve the above objects, the present invention provides the following technical solutions: A trace dust aerosol generator, including a control component and an aerosol generating component. The aerosol generating component includes a vibrating horn, and one side of the expanded opening of the vibrating horn is detachable. A vibrating plate is fixedly installed, and a vortex airflow generating device is provided on the side of the vibrating plate facing away from the vibrating horn. The vortex airflow generating device is connected to an aerosol generating cabin on the side facing away from the vibrating plate;
所述震动片配置成于朝向漩涡气流发生装置一侧放置粉尘颗粒；The vibration piece is configured to place dust particles on the side facing the vortex airflow generating device;
所述震动喇叭配置成带动震动片震动；The vibrating horn is configured to drive the vibrating piece to vibrate;
所述漩涡气流发生装置包括用于固定所述震动片的压膜，所述压膜包括喷气腔室，所述喷气腔室配置成容纳震动片上的粉尘颗粒；且The vortex airflow generating device includes a pressure film for fixing the vibration plate, the pressure film includes a jet chamber, the jet chamber is configured to accommodate dust particles on the vibration plate; and
所述喷气腔室包括周壁，所述周壁上安装有喷气头，所述喷气头设置为多个且多个喷气头绕所述喷气腔室周壁排列，多个喷气头通过通气管连通，所述多个喷气头喷气方向斜向下设置；The jet chamber includes a peripheral wall, and a jet head is installed on the peripheral wall. The plurality of jet heads are arranged around the peripheral wall of the jet chamber. The plurality of jet heads are connected through a vent pipe. The jet direction of multiple jet heads is set obliquely downward;
所述气溶胶发生舱与所述喷气腔室连通，且所述气溶胶发生舱包括气溶胶出口；The aerosol generating cabin is connected with the jet chamber, and the aerosol generating cabin includes an aerosol outlet;
所述控制组件包括与所述喷气头连通的气泵以及用于控制震动喇叭震动的电源；The control assembly includes an air pump connected to the jet head and a power source for controlling the vibration of the vibrating horn;
所述气泵配置成通过喷气头向所述喷气腔室内喷送洁净空气。The air pump is configured to inject clean air into the air injection chamber through an air jet head.
通过采用上述技术方案，电源控制震动喇叭工作，震动喇叭带动震动片震动，使得震动片上的粉尘颗粒震动，多个喷气头斜向下方向喷气，可以使得喷出的气体形成涡旋气流，带动震动的粉尘颗粒向上移动进入气溶胶发生舱中跟气溶胶发生舱的舱壁壁发生碰撞，从而小颗粒粉尘形成气溶胶流出，大颗粒粉尘因重力重新落在震动片上，该装置结构简单，可对微量粉尘进行操作，不会产生粉尘颗粒太多而发生堵塞的现象，稳定性较好。By adopting the above technical solution, the power supply controls the operation of the vibrating horn. The vibrating horn drives the vibrating plate to vibrate, causing the dust particles on the vibrating plate to vibrate. Multiple jet heads eject air obliquely downward, which can cause the ejected gas to form a vortex airflow and drive vibration. The dust particles move upward into the aerosol generating chamber and collide with the bulkhead of the aerosol generating chamber, so that small particles of dust form aerosols and flow out, and large particles of dust fall back on the vibrating plate due to gravity. The device has a simple structure and can When operating with trace amounts of dust, there will be no clogging caused by too many dust particles, and the stability is good.
本发明进一步设置为：还包括外壳，所述外壳包括置物腔，所述震动喇叭安装在所述置物腔内，所述震动片、漩涡气流发生装置、气溶胶发生舱安装在所述置物腔外；The present invention is further configured to: also include a shell, the shell includes a storage cavity, the vibration horn is installed in the storage cavity, and the vibration piece, the vortex airflow generating device, and the aerosol generating cabin are installed outside the storage cavity. ;
所述压膜可拆卸固定安装在所述外壳上，且所述压膜通过卡箍与所述气溶胶发生舱固定连接。The pressed film is detachably and fixedly installed on the housing, and the pressed film is fixedly connected to the aerosol generating cabin through a clamp.
通过采用上述技术方案，压膜可拆卸固定在外壳上固定震动片，使得压膜和震动片均可拆卸，方便对震动片的清洗和更换。By adopting the above technical solution, the pressing film can be detachably fixed on the outer casing to fix the vibration piece, so that both the pressing film and the vibration piece are detachable, which facilitates the cleaning and replacement of the vibration piece.
本发明进一步设置为：所述置物腔内设置有调频器，所述调频器与所述震动喇叭连接，且所述调频器配置成调节震动喇叭的震动频率。The present invention is further configured such that: a frequency modulator is provided in the storage cavity, the frequency modulator is connected to the vibrating speaker, and the frequency modulator is configured to adjust the vibration frequency of the vibrating speaker.
通过采用上述技术方案，调频器可以调节震动喇叭的震动频率，可以根据工作需要来调节震动喇叭的震动频率，从而调节震动片的震动来控制进入气溶胶发生舱中的粉尘颗粒的多少以及速率等，方便控制。By adopting the above technical solution, the frequency modulator can adjust the vibration frequency of the vibrating speaker according to work needs, thereby adjusting the vibration of the vibrating piece to control the amount and rate of dust particles entering the aerosol generating chamber. , easy to control.
本发明进一步设置为：所述通气管连接有浮子流量计，所述浮子流量计配置成监测通气管内的气体流量。The present invention is further configured such that the vent pipe is connected with a float flow meter, and the float flow meter is configured to monitor the gas flow in the vent pipe.
通过采用上述技术方案，方便对洁净空气流量进行监测和调节控制。By adopting the above technical solution, it is convenient to monitor and regulate the clean air flow.
本发明进一步设置为：所述外壳上安装有散热风扇。The present invention is further configured such that a cooling fan is installed on the housing.
通过采用上述技术方案，散热风扇的设置，便于对外壳散热，避免置物腔室内的控制组件工作时发热严重而影响使用寿命。By adopting the above technical solution, the setting of the cooling fan facilitates heat dissipation of the casing and prevents the control components in the storage chamber from generating serious heat during operation and affecting the service life.
本发明进一步设置为：所述震动片设置为硅胶薄膜。The present invention is further configured that: the vibration piece is configured as a silicone film.
通过采用上述技术方案，硅胶薄膜材质较软，拆卸和安装过程中容易操作，不会出现破裂、损坏等情况，易于更换，且因环境变化影响不大。By adopting the above technical solution, the silicone film material is soft, easy to operate during disassembly and installation, will not be broken or damaged, is easy to replace, and has little impact due to environmental changes.
附图说明Description of the drawings
后文将参照附图以及实施例而非限制性的方式详细描述本发明的一些具体实施例。附图中相同的附图标记标示了相同或类似的部件或部分。本领域技术人员应该理解，这些附图未必是按照比例绘制的。Some specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings and examples and not by way of limitation. The same reference numbers in the drawings identify the same or similar parts or portions. Those skilled in the art will appreciate that these drawings are not necessarily drawn to scale.
图1为本发明微量粉尘气溶胶发生器的分解示意图；Figure 1 is an exploded schematic diagram of the trace dust aerosol generator of the present invention;
图2为本发明微量粉尘气溶胶发生器的一个结构示意图；Figure 2 is a schematic structural diagram of the trace dust aerosol generator of the present invention;
图3为本发明微量粉尘气溶胶发生器的另一个结构示意图。Figure 3 is another structural schematic diagram of the trace dust aerosol generator of the present invention.
附图中：1.气溶胶发生舱；2.上卡箍接口；3.卡箍；4.压膜；5.下卡箍接口；6；通气管；7.喷气头；8.震动喇叭；9.硅胶薄膜；10.浮子流量计；11.调频器；12.散热风扇；13.外壳；14.电源插口；15.进气口。In the attached picture: 1. Aerosol generation cabin; 2. Upper clamp interface; 3. Clamp; 4. Press film; 5. Lower clamp interface; 6; Ventilation pipe; 7. Jet head; 8. Vibrating horn; 9. Silicone film; 10. Float flow meter; 11. Frequency regulator; 12. Cooling fan; 13. Shell; 14. Power socket; 15. Air inlet.
具体实施方式Detailed ways
为使本发明实施例的目的、技术方案和优点更加清楚，下面将参照图1至图3对本发明可伸缩式动物笼具的实施例做进一步说明。In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the retractable animal cage of the present invention will be further described below with reference to FIGS. 1 to 3 .
一种微量粉尘气溶胶发生器，包括外壳13，外壳13包括置物腔室，置物腔室内安装有调频器11，调频器11连接有电源和震动喇叭8，外壳13上设置有电源插口14和用于调节调频器11的按钮（图中未表示出），所述震动喇叭8位于置物腔内且震动喇叭8的扩开口处朝向外壳13的顶部，外壳13的顶部上设有通孔，且外壳13的顶部外侧安装有漩涡气流发生装置，漩涡气流发生装置包括压膜4，所述压膜4包括喷气腔室和连接部（图中未表示出），所述连接部上设置通孔，外壳13的顶部设置螺纹孔，压膜4通过螺钉与外壳13的顶部固定连接，所述压膜4和外壳13的顶部之间固定有震动片，所述震动片为硅胶薄膜9，硅胶薄膜9被压膜4压在外壳13的顶部上。A trace dust aerosol generator includes a shell 13. The shell 13 includes a storage chamber. A frequency modulator 11 is installed in the storage chamber. The frequency modulator 11 is connected to a power supply and a vibration speaker 8. The shell 13 is provided with a power socket 14 and a user interface. For adjusting the button of the frequency modulator 11 (not shown in the figure), the vibration speaker 8 is located in the storage cavity and the expanded opening of the vibration speaker 8 faces the top of the housing 13. The top of the housing 13 is provided with a through hole, and the housing A vortex airflow generating device is installed on the outside of the top of 13. The vortex airflow generating device includes a pressure film 4. The pressure film 4 includes a jet chamber and a connecting part (not shown in the figure). A through hole is provided on the connecting part, and the outer casing A threaded hole is provided on the top of 13, and the pressing film 4 is fixedly connected to the top of the housing 13 through screws. A vibration piece is fixed between the pressing film 4 and the top of the housing 13. The vibration piece is a silicone film 9, and the silicone film 9 is The pressing film 4 presses on the top of the housing 13 .
压膜4形状不限，本发明中优选为圆形，压膜4的周壁上设置有通气孔（图中未表示出），通气孔中设有喷气头7，通气孔和喷气头7均设为多个且一一对应，本发明优选为喷气头7为四个且四个喷气头绕压膜4的轴线均列；漩涡气流发生装置还包括通气管6，通气管6将相邻两个喷气头7连通且通气管6与喷气头7一体焊接设置；，四个喷气头7的顺时针沿压膜4的轴线斜向下设置，沿压膜4的径线斜向下设置，具体为喷气头7于喷气腔室内的延伸方向与水平面夹角为15°～60°且与竖直面的夹角为15°～60°，本发明均优选为45°；外壳13上设置有进气孔和出气孔，通气管6与外壳上的出气孔连通，进气孔处通过管路与气泵连接，且进气孔与出气孔通过管路连接（图中均未表示出）。The shape of the pressing film 4 is not limited. In the present invention, it is preferably circular. A vent hole (not shown in the figure) is provided on the peripheral wall of the pressing film 4. An air jet head 7 is provided in the vent hole. Both the vent hole and the air jet head 7 are provided with a vent hole. There are multiple and one-to-one correspondences. In the present invention, it is preferred that the number of air jet heads 7 is four and the four air jet heads are evenly arranged around the axis of the pressure film 4; the vortex airflow generating device also includes a breather tube 6, and the breather tube 6 will have two adjacent ones. The air jet heads 7 are connected and the breather pipe 6 and the air jet head 7 are integrally welded. The four air jet heads 7 are arranged obliquely downward along the axis of the pressure film 4 clockwise and obliquely downward along the diameter of the pressure film 4, specifically as follows: The angle between the extension direction of the jet head 7 in the jet chamber and the horizontal plane is 15°-60° and the angle between the vertical plane and the vertical plane is 15°-60°. In the present invention, the angle is preferably 45°; the outer casing 13 is provided with an air inlet. The vent pipe 6 is connected with the air outlet on the shell, the air inlet is connected to the air pump through a pipeline, and the air inlet and the air outlet are connected through a pipeline (neither shown in the figure).
压膜4的上部连接有卡箍3，压膜4通过卡箍3与气溶胶发生舱1连接，具体实施方式为：压膜4销钉或者螺钉连接有下卡箍接口5，气溶胶发生舱1销钉或者螺钉连接有上卡箍接口2，卡箍3分别与上卡箍接口2和下卡箍接口5固定连接完成压膜4和气溶胶发生舱1的固定连接，喷气腔室与气溶胶发生舱1连通，气溶胶发生舱1顶部设有气溶胶流通口（图中未表示出）。The upper part of the pressing film 4 is connected with a clamp 3, and the pressing film 4 is connected to the aerosol generating cabin 1 through the clamp 3. The specific implementation method is: the pressing film 4 is connected with a lower clamp interface 5 with a pin or screw, and the aerosol generating cabin 1 The upper clamp interface 2 is connected with pins or screws, and the clamp 3 is fixedly connected to the upper clamp interface 2 and the lower clamp interface 5 respectively to complete the fixed connection between the pressure film 4 and the aerosol generating cabin 1, and the jet chamber and the aerosol generating cabin 1 is connected, and the top of the aerosol generating cabin 1 is provided with an aerosol flow port (not shown in the figure).
本发明的优选实施例为：外壳13上进气孔和出气孔之间的管路连接有浮子流量计10，外壳13上还安装有散热风扇12.The preferred embodiment of the present invention is: a float flowmeter 10 is connected to the pipeline between the air inlet and the air outlet on the housing 13, and a cooling fan 12 is also installed on the housing 13.
本发明微量粉尘气溶胶发生器工作时，硅胶薄膜9上放置粉尘颗粒且粉尘颗粒9被压膜4限制在喷气腔室内，于电源插口14处接通电源，使得调频器11工作，震动喇叭8震动，从而带动硅胶薄膜9震动，旋转按钮可以调节调频器11的频率从而调节震动喇叭8的震动频率，改变硅胶薄膜9的震动频率。打开气泵，向通气管6和喷气头7处通洁净空气，四个喷气头7的喷气方向设置，保证喷气头7处喷出的气流形成涡旋气流，吹动硅胶薄膜9上的粉尘颗粒向上运动，浮子流量计10可以监测气体流量，随时根据实验需求来对通气流量进行调节。震动喇叭8带动硅胶薄膜9震动，硅胶薄膜9上的粉尘颗粒震动并在喷气肉7喷出的洁净空气的吹动下向上运动，进入到气溶胶发生舱1内，此时，粉尘颗粒与气溶胶发生舱1的管壁发生碰撞，此时小的粉尘颗粒继续向上移动经由气溶胶流通口流出形成气溶胶，大的粉尘颗粒在重力作用下重新落在硅胶薄膜9上，继续震动碰撞。When the trace dust aerosol generator of the present invention is working, dust particles are placed on the silica gel film 9 and the dust particles 9 are restricted in the air jet chamber by the pressure film 4. The power is turned on at the power socket 14, so that the frequency modulator 11 works and the vibration horn 8 The vibration causes the silicone film 9 to vibrate. The rotating button can adjust the frequency of the frequency modulator 11 to adjust the vibration frequency of the vibration speaker 8 and change the vibration frequency of the silicone film 9 . Turn on the air pump and pass clean air to the ventilation pipe 6 and the air nozzle 7. The air jet directions of the four air nozzles 7 are set to ensure that the air flow ejected from the air nozzle 7 forms a vortex airflow and blows the dust particles on the silica gel film 9 upward. Movement, the float flowmeter 10 can monitor the gas flow and adjust the ventilation flow according to the experimental needs at any time. The vibrating horn 8 drives the silica gel film 9 to vibrate, and the dust particles on the silica gel film 9 vibrate and move upward under the blowing of the clean air ejected from the air jet meat 7, and enter the aerosol generating cabin 1. At this time, the dust particles and the air The pipe wall of the aerosol generation chamber 1 collides. At this time, the small dust particles continue to move upward and flow out through the aerosol flow port to form aerosol. The large dust particles fall back on the silicone film 9 under the action of gravity and continue to vibrate and collide.
本发明结构简单，操作方便，且可针对微量粉尘进行操作，稳定性好；硅胶薄膜9被可拆卸的压膜4固定压在外壳13上，易于更换和清洗，且材质较软，在更换或清洗时不宜损坏；当工作时间较长，外壳13内装置发热时，启动散热风扇12对外壳13的置物腔内进行散热，避免因温度过高发生危险等。The invention has a simple structure, is easy to operate, can operate on trace amounts of dust, and has good stability; the silicone film 9 is fixed and pressed on the housing 13 by the detachable pressing film 4, which is easy to replace and clean, and the material is soft, so when replacing or It should not be damaged during cleaning; when the working time is long and the device inside the casing 13 generates heat, start the cooling fan 12 to dissipate heat in the storage cavity of the casing 13 to avoid danger due to excessive temperature.
以上所述仅是本发明的优选实施方式，应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明原理的前提下，所作出的任何改进和润饰也应视为本发明的保护范围。The above are only the preferred embodiments of the present invention. It should be pointed out that for those of ordinary skill in the art, any improvements and modifications made without departing from the principles of the present invention should also be regarded as modifications and modifications of the present invention. protected range.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710845671.1ACN109513403B (en) | 2017-09-19 | 2017-09-19 | Trace dust aerosol generator |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710845671.1ACN109513403B (en) | 2017-09-19 | 2017-09-19 | Trace dust aerosol generator |
| Publication Number | Publication Date |
|---|---|
| CN109513403A CN109513403A (en) | 2019-03-26 |
| CN109513403Btrue CN109513403B (en) | 2024-03-19 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710845671.1AActiveCN109513403B (en) | 2017-09-19 | 2017-09-19 | Trace dust aerosol generator |
| Country | Link |
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| CN (1) | CN109513403B (en) |
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