A kind of immune labeled slide turntable placement rackTechnical field
The present invention relates to field of medical device, and in particular to a kind of immune labeled slide turntable placement rack is specifically for use inThe biological respinse of immune labeled class.
Background technique
It is immune labeled, it is that applied immunology basic principle --- antigen-antibody reaction, i.e., antigen is in conjunction with antibody specificityPrinciple, make the color developing agent (fluorescein, enzyme, metal ion, isotope) of labelled antibody develop the color to determine group by chemically reactingIntracellular antigen (peptide and protein) is knitted, it is positioned, qualitative and relative quantification research, referred to as immunohistochemistryTechnology or immunocytochemical technique.
Immune labeled instrument generally can be all applied to when carrying out immune processing or label to cell, present immune markNote instrument mainly consists of two parts, label slide turntable and slide turntable placement rack, but present slide turntable placement rack oneAs all only play the role of to slide turntable place, that functionally compares is single, can not adjust the state of glass frame.
Summary of the invention
It is relatively simple and can adjust the immune labeled slide turntable of glass frame state that the present invention is desirable to provide a kind of structurePlacement rack, concrete scheme are as follows:
A kind of immune labeled slide turntable placement rack, including mounting rack, linear motor, bracket, pallet draw needle, locating shaft, rotationMotor, waste liquid tank, turntable and glass frame are equipped with linear motor and locating shaft on the mounting rack, and the linear motor includesFeed screw nut, the feed screw nut are equipped with bracket, and pallet is equipped on the bracket, and drawing needle, institute are equipped on the palletIt states and waste liquid tank is installed on locating shaft and linear motor, it (is to pass through locating shaft in equipment that waste liquid tank is equipped on the locating shaftWith support column installation, so that waste liquid tank installation is more stable, this, which is also due to waste liquid tank, will also hang rotating electric machine), it is described uselessLiquid bath is equipped with rotating electric machine, the turntable driven by rotating electric machine is equipped with above the rotating electric machine, if being equipped on the turntableDry glass frame, the glass frame and drawing needle are correspondingly arranged.
The locating shaft is slidably connected by one end of sliding block and pallet.Pallet two sides can be made to be supported more steadyIt is fixed.
The linear motor includes motor, screw rod, feed screw nut and fixing axle, is equipped with sensor in the fixing axle,Sensor baffle is installed on the feed screw nut.Sensor can cooperate sensor baffle to learn that the position for drawing needle (passes through senseThe position of feed screw nut is answered, to incude bracket, learns the position of pallet, further confirms that and draws the location of needle).
The glass frame includes glass frame upper cover, glass frame pedestal and glass frame bracket, and glass frame pedestal one end is logicalIt crosses shaft one and glass frame upper cover is installed, glass frame pedestal one end is equipped with glass frame bracket, the glass by shaft twoHorse upper cover one end is equipped with leakage fluid dram and liquid injection port, and the glass frame upper cover is drained close to the one side of glass frame pedestal equipped with L-typeSlot, the L-type drainage trough and liquid injection port are equipped with, and for the glass frame pedestal with spring is equipped between turntable, the glass frame is logicalGlass frame bracket is crossed to be mounted on turntable.The setting of spring can allow glass frame to keep state that is vertical or lying low.
Glass frame pedestal lower part is equipped with pull ring.Glass frame needs to be mounted on turntable by glass frame bracket, and needsIt to be adjusted between lying status vertical, the addition of pull ring can cooperate drawing needle, thus by glass frame from vertical shapeState pulls into lying status.
The glass frame upper cover is equipped with buckle relative to the other end of shaft one, and the glass frame pedestal is equipped with groove, instituteIt states buckle and groove is equipped with.So as to which glass frame upper cover and the fitting of glass frame pedestal (are reached the mesh of fixed glass slide).
The buckle is two, described to buckle the two sides for being located at glass frame upper cover.It can preferably guarantee glass frameUpper cover and the fitting of glass frame pedestal.
The glass frame pedestal be equipped with temperature sensor and heater, the glass frame pedestal far from glass frame upper cover oneSide has fin structure.Due to higher to temperature requirement in immune labeled reaction process, joined temperature sensor canThe temperature of glass frame is more accurately detected, and heater can play the role of heating glass frame.The temperature sensor, heatingDevice and glass frame pedestal use integral structure.To avoid temperature losses.Fin structure is produced when can be in conjunction with high speed rotationRaw air-flow realizes cooling faster.
The turntable is equipped with magnetite, and the magnetite is correspondingly arranged with glass frame.Magnetite can when glass frame is vertical withSpring cooperation preferably allows glass frame to keep vertical state.
Elastic connecting contact pilotage is installed, the elastic connecting contact pilotage is equipped with turntable on the pallet.Due in glass frameEquipped with heater, therefore when pallet moves upwards, elastic connecting contact pilotage can be contacted with turntable by the electric wire that sets to plusHot device heat supply.
The invention has the following advantages that
(1) present invention includes turntable, can centrifugal force produced by the high speed rotation by turntable can be by the bubble in glass frameSqueeze discharge.
(2) because drawing needle synchronization lifting to realize the setting of glass frame and lying posture and turn during pallet liftIt changes, is acted so as to carry out the switching between different reagents and emptying when turntable rotates.(when glass frame is needed from tiling to erectingWhen straight state, linear motor drives bracket, to drive pallet, and drives and needle is drawn to rise, so that glass frame is from tiled state quiltDraw needle top to vertical state, when glass frame need from vertically to tiled state when, rotating electric machine of the invention with sensor andController, can control the rotational angle of turntable, to make that needle is drawn to catch on the pull ring of glass frame, thus by glass frame from vertical shapeState is adjusted to tiled state, and when glass frame is in tiled state, it is certain that rotating electric machine of the invention can control turntable rotationAngle will draw needle to break off relations (pull ring of glass frame), later turntable return, needle drawn to continue to move downward with bracket, in turntable high speedIt when rotation, is required to that needle will be drawn to decline, the setting of sensor and sensor baffle on linear motor, is exactly because the above process needsPerceive the position for drawing needle)
(3) glass frame of the invention uses L-type drainage trough, is due to the present invention for the dosage for reducing reagent to the greatest extent, simultaneouslyGuarantee reagent full sheet covering, so the cavity volume between glass frame upper cover and glass slide to be compressed to it is minimum but too smallCavity volume can be conducive to the generation with bubble, and be unfavorable for the elimination of bubble generated, using L-type drainage troughAbove-mentioned contradiction is allowed to reach balance.
(4) due to higher to temperature requirement in immune labeled reaction process, glass frame of the invention joined temperatureSensor can more accurately detect the temperature of glass frame, and the addition of heater can be played the role of heating glass frame.AndAnd glass frame of the invention can combine generated air-flow when high speed rotation to realize cooling faster with fin structure.
Detailed description of the invention
A kind of structural schematic diagram one of immune labeled slide turntable placement rack of Fig. 1 present invention (draws needle to be in upper, slideFrame is in a vertical state)；
A kind of partial structure diagram one of immune labeled slide turntable placement rack of Fig. 2 present invention (draws needle to be in upper, slideFrame is in a vertical state)；
A kind of partial structure diagram two of immune labeled slide turntable placement rack of Fig. 3 present invention (draws needle to be in bottom, slideFrame is in tiled state)；
A kind of partial structure diagram three of immune labeled slide turntable placement rack of Fig. 4 present invention (draws needle to be in bottom, slideFrame is in tiled state)；
Glass frame opening (beat by glass frame upper cover and glass frame pedestal in a kind of immune labeled slide turntable placement rack of Fig. 5 present inventionOpen) structural schematic diagram one of state；
Glass frame opening (beat by glass frame upper cover and glass frame pedestal in a kind of immune labeled slide turntable placement rack of Fig. 6 present inventionOpen) structural schematic diagram two of state；
Glass frame opening (beat by glass frame upper cover and glass frame pedestal in a kind of immune labeled slide turntable placement rack of Fig. 7 present inventionOpen) structural schematic diagram three of state；
(glass frame upper cover and glass frame pedestal close glass frame closure in a kind of immune labeled slide turntable placement rack of Fig. 8 present inventionClose) structural schematic diagram one of state；
(glass frame upper cover and glass frame pedestal close glass frame closure in a kind of immune labeled slide turntable placement rack of Fig. 9 present inventionClose) structural schematic diagram two of state；
Wherein label: 1. glass frames；11. glass frame upper cover；12. glass frame pedestal；13. shaft one；14. shaft two；15. slideFrame bracket；16. pull ring；17. buckle；18. groove；19. liquid injection port；110. leakage fluid dram；111.L type drainage trough；112. glass slide；113. fin structure；2. mounting rack；3. linear motor；31. motor；32. screw rod；33. feed screw nut；34. fixing axle；35. passingSensor；36. sensor baffle；4. waste liquid tank；41. 5. locating shaft of support column；51. sliding block；61. turntable；62. rotating electric machine；71.Bracket；72. pallet；73. drawing needle；74. circuit elastic connecting contact pilotage；8. magnetite；9. spring.
Specific embodiment
It below with reference to Fig. 1-9, is further described, a kind of immune labeled slide turntable placement rack, including mounting rack 2,Linear motor 3, bracket 71, pallet 72 draw needle 73, locating shaft 5, rotating electric machine 62, waste liquid tank 4, turntable 61 and glass frame 1, peaceIt shelves and linear motor 3 and locating shaft 5 is installed on 2, linear motor 3 includes feed screw nut 33, and feed screw nut 33 is equipped with bracket71, pallet 72 is installed on bracket 71, is equipped on pallet 72 and draws needle 73, waste liquid tank is installed on locating shaft 5 and linear motor 34, being equipped in waste liquid tank 4(equipment on locating shaft 5 is installed by locating shaft 5 and support column 41, so that waste liquid tank 4 is installedMore stable, this, which is also due to waste liquid tank 4, will also hang rotating electric machine 62), waste liquid tank 4 is equipped with rotating electric machine 62, rotating electric machine 62Top is equipped with the turntable 61 driven by rotating electric machine 62, and several glass frames 1 are equipped on turntable 61, and glass frame 1 and drawing needle 73 are rightIt should be arranged.Locating shaft 5 is slidably connected by sliding block 51 and one end of pallet 72.72 two sides of pallet can be made to be supported moreStablize.Linear motor 3 includes motor 31, screw rod 32, feed screw nut 33 and fixing axle 34, is equipped with sensor in fixing axle 3435, sensor baffle 36 is installed on feed screw nut 33.Sensor 35 cooperates sensor baffle 36 that can learn the position for drawing needle 73It sets and (position of pallet 72 is learnt to incude bracket 71 by the position of induction feed screw nut 33, further confirms that and draws needle 73Location).
Glass frame 1 includes glass frame upper cover 11, glass frame pedestal 12 and glass frame bracket 15, and 12 one end of glass frame pedestal is logicalIt crosses shaft 1 and glass frame upper cover 11 is installed, 12 one end of glass frame pedestal is equipped with glass frame bracket 15 by shaft 2 14,11 one end of glass frame upper cover is equipped with leakage fluid dram 110 and liquid injection port 19, and glass frame upper cover 11 is set on one side close to glass frame pedestal 12Have L-type drainage trough 111, L-type drainage trough 111 and liquid injection port 19 are equipped with, glass frame pedestal 12 between turntable 61 be equipped with spring9, glass frame 1 is mounted on turntable 61 by glass frame bracket 15.The setting of spring 9 can allow glass frame 1 keep it is vertical orThe state to lie low.12 lower part of glass frame pedestal is equipped with pull ring 16.Glass frame 1 needs to be mounted on turntable 61 by glass frame bracket 15On, and need to be adjusted between lying status vertical, the addition of pull ring 16, which can cooperate, draws needle 73, thus by glass frame1 pulls into lying status from vertical state.
It is two that glass frame upper cover 11, which is equipped with buckle 17(buckle 17 relative to the other end of shaft 1,17 difference of bucklePositioned at the two sides of glass frame upper cover 11.Can preferably guarantee that glass frame upper cover 11 and glass frame pedestal 12 are bonded), glass frame bottom12 are equipped with groove 18, and buckle 17 and groove 18 are equipped with.So as to which glass frame upper cover 11 and glass frame pedestal 12 are pastedIt closes (achieving the purpose that fixed glass slide 112).
Glass frame pedestal 12 is equipped with temperature sensor and heater, side of the glass frame pedestal 12 far from glass frame upper cover 11With fin structure 113.Due to higher to temperature requirement in immune labeled reaction process, joined temperature sensor canThe temperature of glass frame is more accurately detected, and heater can play the role of heating glass frame.Temperature sensor, heater andGlass frame pedestal uses integral structure.To avoid temperature losses.Fin structure 113 is produced when can be in conjunction with high speed rotationAir-flow realize cooling faster.
Turntable 61 is equipped with magnetite 8, and magnetite 8 is correspondingly arranged with glass frame 1.Magnetite 8 can be when glass frame 1 be vertical and bulletSpring 9, which cooperates, preferably allows glass frame to keep vertical state.
Elastic connecting contact pilotage 74 is installed, elastic connecting contact pilotage 74 is equipped with turntable 61 on pallet 72.Due in glass frame 1Equipped with heater, therefore when pallet moves upwards, elastic connecting contact pilotage 74 can contact the electric wire by setting with turntable 61Give heater heat supply.
The present invention includes turntable 61, can centrifugal force produced by the high speed rotation by turntable 61 can will be in glass frame 1Bubble squeeze discharge.
In 61 lifting process of slide turntable of the present invention because draw 73 synchronization lifting of needle to realize the setting of glass frame 1 withThe many attitude that lies low conversion, so as to carry out the switching and emptying movement between different reagents when turntable 61 rotates.(work as slideWhen frame 1 is needed from tiling to vertical state, linear motor 3 drives bracket 71, to drive pallet 72, and drives and draws on needle 73Rise, so that glass frame 1 is pushed up by drawing needle 73 to vertical state from tiled state, when glass frame 1 need from vertically to tiled state when,Rotating electric machine 62 of the invention has sensor and controller, can control the rotational angle of turntable 61, to make that needle 73 is drawn to hookThe firmly pull ring 73 of glass frame 1 is in tiled state in glass frame 1 so that glass frame 1 is adjusted to tiled state from vertical stateWhen, rotating electric machine 62 of the invention can control turntable 61 and turn an angle, and will draw the unhook (pull ring of glass frame 1 of needle 7316), 61 return of turntable, drawing needle 73 continue to move downward, in turntable high-speed rotation, are required to that needle 73 will be drawn with bracket 71 laterDecline, the setting of sensor 35 and sensor baffle 36 on linear motor 3, exactly because the above process, which needs to perceive, draws needle 73Position)
Glass frame 1 of the invention uses L-type drainage trough 111, is due to the present invention for the dosage for reducing reagent to the greatest extent, simultaneouslyGuarantee reagent full sheet covering, so the cavity volume between glass frame upper cover 11 and glass slide 112 to be compressed to it is minimum (simultaneouslyVolume is minimum can also to reduce volatilization as far as possible, will lead to sample and reagent insufficient contact after reagent volatilization or entirely without connecingTouching carries out insufficient or directly results in failure so as to cause immune labeled reaction), but too small cavity volume can be conducive toThe generation of bubble, and it is unfavorable for the elimination of bubble generated, above-mentioned contradiction can be allowed to reach using L-type drainage trough 111Balance.
Due to higher to temperature requirement in immune labeled reaction process, glass frame 1 of the invention joined temperature biographySensor can more accurately detect the temperature of glass frame 1, and the addition of heater can be played the role of heating glass frame 1.AndAnd glass frame 1 of the invention can combine generated air-flow when high speed rotation to realize cooling faster with fin structure 113.
The above content is combine the preferred embodiment of the present invention to made by provided technical solution further specificallyIt is bright, and it cannot be said that the present invention specific implementation be confined to it is above-mentioned these explanation, for the common skill of the technical field of the inventionFor art personnel, without departing from the inventive concept of the premise, the simple deduction or replace made all should be considered as this hairBright protection scope.