Disclosure of Invention
In order to solve all or part of the above problems, the present invention provides a blood centrifuge module for a centrifuge, which not only can collect various products generated after blood is separated without requiring an operator to have a high level of professional operation, but also can reduce the risk of bacteria invading during the collection.
The present invention provides a blood centrifugation assembly for a centrifuge, comprising: a horizontal vessel mountable in parallel on a chuck rotor of the centrifuge, the horizontal vessel having left and right centrifugal chambers spaced apart along an axial direction thereof; the exhaust valve is arranged on the horizontal container and is connected with the left centrifugal cavity and the right centrifugal cavity; the pipeline assembly comprises a flexible trunk, a first flexible branch and a second flexible branch, wherein the structures of the first flexible branch and the second flexible branch are the same, one end of the flexible trunk is simultaneously connected with the first end of the first flexible branch and the first end of the second flexible branch, the other end of the flexible trunk is used for injecting blood and extracting products generated after blood is separated, the second end of the first flexible branch is connected with the left end of the horizontal container and is communicated with the left centrifugal cavity, and the second flexible branch is connected with the right end of the horizontal container and is communicated with the right centrifugal cavity.
Compared with the prior art, the blood centrifugal component for the centrifugal machine adopts the horizontal container to be arranged on the chuck type rotor of the centrifugal machine in parallel, so that the left centrifugal cavity and the right centrifugal cavity do not rotate around the axis of the left centrifugal cavity and the right centrifugal cavity, but rotate around the axis of the chuck type rotor, the blood can be ensured to generate larger centrifugal force in the separation process, and the blood centrifugal component is promoted to separate the blood more efficiently. Meanwhile, the blood centrifugal component can collect various products generated after blood is separated without a high professional operation level of an operator, and the blood and various products generated after the blood is separated can not be basically contacted with external air in the separation process and the collection process, so that the risk of bacteria introduced by the operator in the collection process can be effectively reduced.
The blood centrifugal component for the centrifugal machine has the advantages of simple structure, convenient manufacture, safe and reliable use and convenient implementation, popularization and application.
Detailed Description
Embodiments of the technical scheme of the present invention will be described in detail below with reference to the accompanying drawings. The following examples are only for more clearly illustrating the technical aspects of the present invention, and thus are merely examples, and are not intended to limit the scope of the present invention.
FIG. 1 is a perspective view of a blood centrifugation assembly for a centrifuge according to a first embodiment of the present invention; fig. 2 is a cross-sectional view of a horizontal vessel for a blood centrifugation assembly for a centrifuge according to a first embodiment of the present invention. As shown in fig. 1 and 2, the blood centrifugation assembly 10 mainly includes a horizontal vessel 1, a tube assembly 2, and an exhaust valve 3. The horizontal vessel 1 can be mounted parallel (i.e. perpendicular to the axis of the chuck rotor) to the chuck rotor of the centrifuge so that the chuck rotor of the centrifuge can rotate the horizontal vessel 1 about the axis of the chuck rotor. The horizontal container 1 is preferably in the shape of a solid of revolution, and preferably has a cylindrical shape with both ends tapered. The horizontal vessel 1 has left and right centrifugal chambers 14, 15 spaced apart along its axis. The exhaust valve 3 is provided on the horizontal vessel 1 and connected to the left and right centrifugal chambers 14 and 15 for exhausting gas in the left and right centrifugal chambers 14 and 15 to allow blood to enter into the respective chambers. The line assembly 2 comprises a first flexible branch 21 and a second flexible branch 22 and a flexible trunk 23. The first flexible branch 21 and the second flexible branch 22 have the same structure, so as to ensure that the fluid in the pipeline assembly 2 (i.e. the blood or the product generated by the separated blood) flows synchronously and uniformly in the left centrifugal cavity 14 and the right centrifugal cavity 15. One end of the flexible trunk 23 is connected to both the first end of the first flexible branch 21 and the first end of the second flexible branch 22, while the other end of the flexible trunk 23 is used for injecting blood and extracting products produced by separating blood, the second end of the first flexible branch 21 is connected to the left end 1a of the horizontal container 1 and communicates with the left centrifugal chamber 14, and the second flexible branch 22 is connected to the right end 1b of the horizontal container 1 and communicates with the right centrifugal chamber 15.
In use, the blood centrifuge module 10 for a centrifuge according to an embodiment of the present invention is configured such that the horizontal container 1 is first mounted in parallel on the chuck rotor of the centrifuge, and then blood is simultaneously and uniformly added into the left and right centrifugal chambers 14 and 15 of the horizontal container 1 through an injector (e.g., a medical syringe) connected to the tube module 2, and after the blood adding operation is completed, the centrifuge is started, so that the horizontal container 1 rotates at a high speed along with the chuck rotor about its axis under the action of the centrifuge, and the left and right centrifugal chambers 14 and 15 can separate the blood therein independently until the components in the blood are completely separated, and then the centrifuge is closed again after the collection is completed by drawing the components (i.e., the separated matters in the blood) in the left and right centrifugal chambers 14 and 15 layer by layer through an extractor (e.g., a medical syringe) connected to the tube module 2 without closing the centrifuge. Compared with the prior art, the blood centrifugal component 10 for the centrifugal machine adopts the horizontal container 1 to be arranged on the chuck type rotor of the centrifugal machine in parallel, so that the left centrifugal cavity 14 and the right centrifugal cavity 15 do not directly rotate around the axis of the left centrifugal cavity and the right centrifugal cavity but rotate around the axis of the chuck type rotor, the blood is ensured to generate larger centrifugal force in the separation process, and the blood centrifugal component 10 is promoted to separate the blood more efficiently.
Meanwhile, the blood centrifuge module 10 for a centrifuge according to the embodiment of the present invention can collect various products generated after separation of blood without requiring an operator to have a high level of professional operations at all, and can effectively reduce the risk of introducing bacteria during the collection by the operator since the blood and various products generated after separation thereof can be substantially free from external air during the separation and collection.
Since the contents of the various components in the blood are not the same, in order to facilitate more accurate collection of the components having the smaller contents, the blood centrifuge assembly 10 may be constructed such that the radial dimension of the left end of the left centrifuge chamber 14 becomes smaller gradually in the right-to-left direction, and the radial dimension of the right portion of the right centrifuge chamber 15 becomes smaller gradually in the left-to-right direction, wherein the horizontal vessel 1, the left centrifuge chamber 14, the right centrifuge chamber 15, the liquid inlet and outlet 14a of the left centrifuge chamber 14, and the liquid inlet and outlet 15a of the right centrifuge chamber 15 are coaxial. Through a number of experiments, it was verified that the collection of the components of the blood, which are relatively small, is more advantageous when both the left end of the left centrifugal chamber 14 and the right portion of the right centrifugal chamber 15 are tapered to be (13-14): 32-33. Since the left centrifugal cavity 14 and the right centrifugal cavity 15 can also influence the external shape of the horizontal container 1, when the left end of the left centrifugal cavity 14 and the right part of the right centrifugal cavity 15 are both in a conical shape with the taper of (13-14): (32-33), more convenient packaging and transportation are facilitated.
In this embodiment, the horizontal container 1 comprises a left cup 11 connected to a first flexible branch 21 and a right cup 12 connected to a second flexible branch 22, and an intermediate connecting block 13 connecting the left cup 11 and the right cup 12 at the same time and capable of mounting the exhaust valve 3. Wherein a left centrifugal chamber 14 is formed between the left cup 11 and the intermediate connecting block 13, and a right centrifugal chamber 15 is formed between the right cup 12 and the intermediate connecting block 13. The connection between the left cup 11 and the middle connecting block 13 and the connection between the right cup 12 and the middle connecting block 13 can be detachable connection or fixed connection, such as bolt connection, welding, bonding or integral molding. Preferably, the left centrifugal cavity 14 and the right centrifugal cavity 15 are mirror symmetrical with respect to the middle connecting block 13, so that the left centrifugal cavity 14 and the right centrifugal cavity 15 can synchronously separate equal amounts of blood, and can synchronously and uniformly output various products generated after the blood is separated, so that the situation that one of the products is equal to the other product is avoided.
In this embodiment, the horizontal container 1 comprises a left elbow 16 arranged between the first flexible branch 21 and the left cup 11 and a right elbow 17 arranged between the second flexible branch 22 and the right cup 12, wherein the port 16a of the left elbow 16 connected with the first flexible branch 21 is opposite to the direction of the exhaust port 3a of the exhaust valve 3, and the port 17a of the right elbow 17 connected with the second flexible branch 22 is opposite to the direction of the exhaust port 3a of the exhaust valve 3. During use, the exhaust port 3a of the exhaust valve 3 faces upwards, and the port 16a of the right elbow 17 and the port 17a of the right elbow 17 face downwards at the same time, so that the exhaust valve 3 can perform smooth exhaust, and meanwhile, the first flexible branch 21 and the second flexible branch 22 are not easy to generate large bending at the positions corresponding to the elbows to prevent the flow of fluid therein.
In this embodiment, the first flexible branch 21 and the second flexible branch 22 are flexible branch pipes, and the flexible trunk 23 includes a flexible trunk pipe 231 and a tee 232, wherein three openings of the tee 232 are sequentially connected to a first end of the flexible trunk pipe 231, the flexible branch pipe of the first flexible branch 21, and the flexible branch pipe of the second flexible branch 22, and a second end of the flexible trunk pipe 231 is used for injecting blood and extracting a product generated by separating blood. The flexible trunk tube 231 is made of the same material as the flexible trunk tube, and may be made of non-toxic and harmless rubber, resin, etc., but is preferably a medical infusion tube. Preferably, the through-flow cross-sectional area of the first flexible branch 21 gradually decreases from the horizontal container 1 toward the tee 232, so that the fluid in the first flexible branch has higher transparency as the fluid is closer to the tee 232, so as to facilitate people to accurately distinguish various products generated by blood separation, and further help people to accurately collect various products, such as autologous platelet rich plasma (PRP for short).
In this embodiment, a guide channel 13a is provided on the intermediate link 13, which is not in communication with both the left centrifugal chamber 14 and the right centrifugal chamber 15, the guide channel 13a being capable of receiving the flexible trunk pipe 231 and allowing the flexible trunk pipe 231 to pass out of the intermediate link 13 after being bent therein. In fact, the connection between the first flexible branch 21 and the left elbow 16 and the connection between the second flexible branch 22 and the right elbow 17 are extremely breakable, but are constructed in the manner described above, even if one pulls and retracts the pipeline assembly 2 continuously and repeatedly, the connection between the first flexible branch 21 and the left elbow 16 and the connection between the second flexible branch 22 and the right elbow 17 are not easily breakable. In addition, the structure can facilitate the pipeline component 2 to extend out of or penetrate through the chuck-type rotor along the radial direction of the chuck-type rotor, so that the pipeline component 2 can automatically relieve adverse phenomena caused by torsion, such as coiling, knotting or stacking, in the rotation process of the chuck-type rotor.
The embodiment shown in fig. 3 differs from the embodiment shown in fig. 1 or 2 only in that the line assembly 2 further comprises a fork line 24 and a tubular fitting 25. In detail, in the embodiment shown in fig. 3, the pipeline assembly 2 further comprises more than two fork tubes 24, wherein the more than two fork tubes 24 are each connected to the second end of the flexible trunk tube 231. If the number of the cross-pipes 24 is two, one of them may be used for the injection of blood and the other may be used for the extraction of products (e.g. PRP) resulting from the separation of blood, of course the cross-pipes 24 injected with blood are also used for the extraction of products (e.g. serum and red blood cells) resulting from the separation of blood after the injection has been completed. In the embodiment shown in fig. 3, the line assembly 2 further comprises an externally threaded tubular fitting 25, the tubular fitting 25 being provided on the end of the fork tube 24 remote from the flexible trunk tube 231. Wherein the external threads on the tubular fitting 25 are primarily used to connect an injector or an extractor, providing stability and tightness of the connection therebetween.
In the description of the present application, it should be understood that the terms "upper," "lower," "left," "right," "axial," "radial," "circumferential," and the like indicate an orientation or a positional relationship based on that shown in the drawings, and are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the apparatus or element in question must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. In the description of the present invention, the meaning of "plurality" is two or more unless specifically defined otherwise.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and not for limiting the same; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the invention, and are intended to be included within the scope of the appended claims and description. In particular, the technical features mentioned in the respective embodiments may be combined in any manner as long as there is no structural conflict. The present invention is not limited to the specific embodiments disclosed herein, but encompasses all technical solutions falling within the scope of the claims.