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CN108152285A - A kind of fully-automatic intelligent urine iodine analyzer and its method of work - Google Patents

A kind of fully-automatic intelligent urine iodine analyzer and its method of work
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Publication number
CN108152285A
CN108152285ACN201810137209.0ACN201810137209ACN108152285ACN 108152285 ACN108152285 ACN 108152285ACN 201810137209 ACN201810137209 ACN 201810137209ACN 108152285 ACN108152285 ACN 108152285A
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vertical
sample
driving
turntable
displacement
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王鲁生
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Abstract

The present invention relates to a kind of fully-automatic intelligents to urinate iodine analyzer, including casing, sample carriers mechanism, reagent liquid-adding device, light path detection, sample integrated treatment mechanism, waste product slot and electric-control system, using Quantitative colorimetric method, by the way that reagent disc rotation is controlled to realize the point-to-point operation of classes of agents;Mixing to test agent is realized by using sample-adding agitating device, sample cross contamination is avoided, improves mixing efficiency;The addition function of color developing agent and oxidant is realized by using double reagent needle sample arm, shortens detection time, saves equipment inside and outside space;Have automatic interpretation result, automatic printing function of reporting, improve urine iodine and detect the degree of automation, efficiently avoid error caused by being loaded by hand, improve urine examination accuracy of detection and detection efficiency, reduce testing cost.

Description

A kind of fully-automatic intelligent urine iodine analyzer and its method of work
Technical field
The invention belongs to field of analytic instrument, and in particular to a kind of fully-automatic intelligent urinates iodine analyzer.
Background technology
Iodine is one of trace element with important biomolecule effect, and the growth and development, metabolism with human body are closely related,Therefore the Iodine nutrition situation of crowd is particularly important after accurate evaluation crowd's iodine deficiency degree and monitoring in time enriches the iodine.Urinate iodineExcretion is closely related with Iodine intake, is the important indicator for evaluating human body iodine nutrition level and the curative effect that enriches the iodine.Iodine is urinated by detectionCan diagnose human body whether iodine deficiency, so as to diagnose human body whether with certain disease or prediction disease.
However, the content of iodine in human urine is few, only million/zero is several, and matrix composition is complicated, individual differenceDifferent big, assay method requires all highers in sensitivity, accuracy, antijamming capability, stability, current overwhelming majority measure sideMethod is manual operations, and error is larger.In addition urinary fractions are complicated, and the substance for interfering Iodine assay is more, although the analysis method of iodineIt is numerous, but iodine is still one of element of more difficult measure in nonmetalloid analysis, therefore it is complex to urinate iodide determination work.
The problem of for current above-mentioned urine Iodine assay and analysis, currently existing scheme generally comprises following several typesNot:
1st, stress to improve the reagent of accuracy of detection or assay method and means:
King adds a kind of urine iodine test reagent kit disclosed in adopted CN1811394A patents, involved urine Iodine assay methodHave many advantages, such as at low cost, easy to be quick.Similarly there is a kind of urine iodine of patent of invention application No. is 201510431403.6Assay kit and its application, the new patent application No. is 201220196514.5 urinate iodine concentration detection device, application No. is201210135472.9 patent of invention urine iodine concentration detection method and device, but the above method only stresses certain single measurePerformance or method can not accomplish to automatically determine, and urine Iodine assay precision need to be improved.
2nd, manually-operated semi-automatic urine iodine analytical equipment is needed:
201611262242.3 patent of invention of Patent No. discloses urine iodinetric analysis system, including drop bottle, squeezes dressIt puts, detection reagent etc., has many advantages, such as easy to operate, reaction time consumption is few.Similarly also application No. is 201621402084.2Utility model patent it is a kind of urine iodine analyzer, application No. is a kind of 201110315676.6 quantitative determinations of patent of inventionThe method of iodine is urinated, grant number is 02234266.4 utility model patent iodine element automatic detector, and above-mentioned technology has been provided withCertain automatic detection function, but the structure having is also relatively complex, determination step is cumbersome, and measurement efficiency needs to be further improved.
3rd, tentatively has the urine iodine analytical equipment of full-automatic function:
The new patent of Patent No. 201620092824.0 discloses a kind of full-automatic urine iodine analyzer, real including rotationDisk is tested, sample loading gun mouth, sample cell, processing bottle and cuvette, has the mechanical arm of liquid conditioner function and reaction can be filledChemical agent addition bar of agent etc. is, it can be achieved that more completely urinate iodine analytic function.The device have structure is relatively simple, detection efficiency compared withThe advantages that high.Above-mentioned technology tentatively has urine iodine automatic measurement function, but also there are drawbacks for above-mentioned technology:According to patent201620092824.0 it is known that the additive being configured can only be added to processing bottle by the chemical agent addition bar in the programIn, and if when using the spectrophotometry in urine iodine analysis, color developing agent and oxidant need to be added step by step into test agent, and showToner and oxidant are separately stored and are individually filled, and relevant programme is not provided in the technical solution.Also, above-mentioned technologyIn, for the reagent that chemical addition agent and sample are mixed in processing bottle, the technological means and scheme of mixing are not provided, thisIt is unreasonable in practical applications;It is mentioned in this programme and negative pressure, but basis is taken out to liquid in processing bottle using inhaling negative pressure moduleActual conditions, processing bottle are shedding motion, and internal liquid remains an atmospheric pressure state, according to atmospheric pressure equilibrium principle,This kind of scheme is implemented obviously unreasonable;And mention in scheme and the liquid in processing bottle being mixed using sampling probe realization, butBe carry out to it is first processing bottle in liquid mixing after, sampling probe has just formed pollution sources, can not carry out it is secondary be used in mixed way,Cause the equipment that can only complete mixed once function.Finally, it is mentioned in the program using sample loading gun mouth using disposable rifle mouth, andAnd useless rifle mouth disk is additionally provided among experiment plate, but to realize continuous all automatic measurement, then need used rifle every timeMouth, which is pulled up, to be put into useless rifle mouth disk, it is clear that does not provide related enforcement body and corresponding method in the present invention.
To sum up, existing urine iodine analyser function is more single, even if having the equipment of higher automation, there is also larger disadvantagesDisease, degree of automation and efficiency are extremely limited, and it is extremely urgent how to design a kind of efficient, succinct, full automatic urine iodine analyzer.
Invention content
The purpose of the present invention is to provide a kind of realization automatically continue quantitative fixed point detection, avoid sample cross infection,Shorten detection stand-by period, the fully-automatic intelligent urine iodine analyzer for improving detection efficiency, improving level of integrated system.
The technical solution adopted by the present invention to solve the technical problems is:A kind of fully-automatic intelligent urinates iodine analyzer, includingCasing, sample carriers mechanism, reagent liquid-adding device, light path detection, sample integrated treatment mechanism, waste product slot and automatically controlled systemSystem, casing include top half and lower half portion, and sample integrated treatment mechanism is provided in top half, and lower half portion is equipped with sampleThis carrier body, reagent liquid-adding device, light path detection, sample integrated treatment mechanism, waste product slot and electric-control system, casingThe upper surface of lower half portion is provided with reagent adding trough, and the side of casing is equipped with power interface, communication interface, thermovent and power supplySwitch.
Sample carriers mechanism includes sample turntable, turntable transport mechanism, rotary disc driving mechanism.Sample turntable includes turntable diskBody, sample cell bit array, shaft open-work, test tube support disk body, specimen cup slot position support array, turntable disk body is with certain thicknessThe disc structure of degree is arranged on the upper surface of casing lower half portion, and three circle circular holes are uniformly distributed on turntable disk body, and circular hole is straightDiameter is slightly coarser than reagent pipe diameter, and the circular hole often enclosed is radially consistent along turntable disk body, and every group of corresponding three circular hole is radially alignedDistribution, the array of three circle circular hole compositions is sample cell bit array, and three circle circular holes are respectively from inner ring to outer ring:Liquid-transfering gun mouth slot battle arrayRow, specimen cup slot array, reaction cup slot array place liquid relief rifle mouth, specimen cup slot array, reaction on liquid-transfering gun mouth slot arrayCup slot array then places sample tube and reaction test tube respectively, and turntable disk body is provided centrally with the through-hole of major diameter, is shaftOpen-work to install turntable bearing, waste product slot is provided in the inner annular space of turntable bearing, is provided on test tube support disk bodySpecimen cup slot position supports array, and specimen cup slot position support array is corresponded with sample cell bit array position, sample cell bit arrayIt is set on test tube support disk body, totally three circles, the slot position often enclosed is radially consistent along test tube support disk body, every group of corresponding three slotThe radially aligned distribution in position, it is pyramidal structure that specimen cup slot position, which supports each slot position shape in array, and test tube support disk body is pacifiedDress is fixed on turntable disk body lower end, connect and fixes with turntable disk body, and rotated together with turntable disk body by stent.Turntable passesMechanism is sent to include turntable bearing, shaft, the driven synchronous pulley of turntable, turntable driving synchronous pulley, turntable synchronous belt, turntable bearingInner ring lower end connection shaft, the fixed turntable disk body of inner ring upper end connection and test tube support disk body, the outer shroud connection of turntable bearingIt is fixed on instrument support, shaft bottom end is provided with the driven synchronous pulley of turntable, and the driven synchronous pulley of turntable is synchronized by turntableBand is connect with turntable driving synchronous pulley, and turntable driving synchronous pulley is arranged on turntable driving motor, and electricity is driven by turntableThe driving of machine drives turntable driving synchronous pulley rotation.Rotary disc driving mechanism includes turntable driving motor, turntable driving motor branchFrame, turntable driving motor frame bottom are fixed on instrument, and turntable driving motor is mounted on turntable driving motor stent, turntableThe output revolving shaft of driving motor is fixed at turntable driving synchronous pulley axle center, and turntable driving motor is also connected with driving moduleIn corresponding motor driver.
Reagent liquid-adding device includes reagent pipetting volume mechanical arm, quantitatively pinpoints liquid feeding system, quantitatively pinpoints liquid feeding system and includesQuantitative plunger pump, liquid transfer gun head carrier, liquid feeding pipe-line system, quantitative plunger pump, liquid transfer gun head carrier, liquid feeding pipe-line system areTwo sets, liquid feeding pipe-line system is common pipe-line system, connects quantitative plunger pump and liquid transfer gun head carrier, quantitative plunger pump peace respectivelyDress is fixed on instrument internal stent, including color developing agent quantitative plunger pump and oxidant quantitative plunger pump, liquid transfer gun head carrier packetContaining color developing agent sample-adding bar, oxidant sample-adding bar, color developing agent is loaded bar and connects color developing agent quantitative plunger pump by liquid feeding pipe-line systemEntrance, oxidant sample-adding bar pass through liquid feeding pipe-line system connect oxidant quantitative plunger pump entrance.
Light path detection includes colorimetric carrier, light path detection module, and colorimetric carrier includes colorimetric pool, hood, colorimetricPond pillar, colorimetric pool are two layers inside and outside annular, inside and outside colorimetric pool between two layers can holding test tubes, outermost layer corresponds on turntable disk bodySample cell bit array it is corresponding with the annulate lamella of colorimetric pool, hood be ring sector structure, bottom hollow out, positioned at turntable disk bodyAbove the corresponding sample cell bit array of upper outermost layer, hood is fixed on the casing lower half portion above light path detection moduleUpper surface on, colorimetric pool pillar be elongated stanchions, quantity be four, colorimetric pool pillar upper end is fixed with colorimetric pool, lower end pacifyDress is fixed on casing.Light path detection module includes special light emitting diode, silicon photo diode, and special light emitting diode is arranged onThe outside of colorimetric pool cyclic structure, below hood, special light emitting diode is also connected with controller, silicon photo diode installationOn the opposite of special light emitting diode, in the inside of colorimetric pool cyclic structure, silicon photo diode and special light emitting diode are pairs ofIt uses, silicon photo diode is connected with controller.
System that sample integrated treatment mechanism includes horizontal displacement mechanism, vertical deviation mechanism, sample are quantitatively handled up moves back pipe machineStructure, waste product slot are rounded cylindrical structure, and the outer diameter of waste product slot is smaller than shaft open-work, and waste product slot is fixed in turntable disk bodyCentre.
Electric-control system includes lower computer control system, upper computer control system, and lower computer control system includes controller, drivesDynamic model group, power module, communication module, controller are the control core of a whole set of instrument, are arranged on instrument internal, controller connectionModule, power module, communication module are driven, driving module includes multiple drivers, respectively drives turntable driving motor, traversing driveDynamic motor, horizontal displacement driving motor, vertical displacement driving motor, the input terminal connection power interface of power module, output terminalConnection driving module and communication module, communication module are connect with communication interface.Upper computer control system includes host computer computer, onThe electromechanical brain in position is connect by Serial Port Line with communication interface.
Specifically, reagent pipetting volume mechanical arm include vertical driving motor, vertical driving transmission system, photoelectric sensor system,Traversing driving motor, the vertical axis of reagent pipetting volume, reagent pipetting volume transverse arm, liquid feeding mechanical arm protective cover, adds laterally driven transmission systemLiquid machinery arm support.
Vertical driving motor is fixed on the downside of liquid feeding machinery arm support, the correspondence in vertical driving motor connection driving moduleMotor driver.
Vertical driving transmission system includes vertical driving and synchronizes belt tensioner pulley, vertical driving synchronous belt, vertical driving synchronizationBelt wheel, vertical driving synchronous belt tooth plate, vertical axis pallet, the output that vertical driving synchronous pulley is mounted on vertical driving motor turnOn axis, vertical driving synchronizes belt tensioner pulley and is mounted remotely from vertical driving synchronous pulley side by shaft, and vertical driving synchronizesBelt tensioner pulley and vertical driving synchronous pulley are in approximately the same plane, and axle axis is parallel, and vertical driving synchronous pulley is sleeved onOn the vertical axis of reagent pipetting volume, by bearing and the vertical axis connection of reagent pipetting volume, and the vertical axis of reagent pipetting volume can be same in vertical drivingIt is moved up and down in bearing at step belt wheel axle center, vertical driving synchronous belt is fixed on the inside of vertical driving synchronous belt tooth plateOn, the component that need to be driven is installed in outside, and vertical driving synchronous belt tooth plate is also connected with being fixed on vertical axis pallet, vertical axis palletShape is semicircle slab construction, connect fixation with the lower end of the vertical axis of reagent pipetting volume by bearing at axle center, side with it is verticalIt drives synchronous belt truss plate connection and fixation, the vertical axis of reagent pipetting volume can rotate, and moved up with vertical axis pallet around vertical axis palletIt slides.
Photoelectric sensor system is photoelectric sensor, including transmitting module, receiving module and Signal-regulated kinase, totally two sets,The side of vertical driving synchronous belt and traversing driving synchronous belt is mounted on by stent respectively.
Traversing driving motor is fixed on the instrument liquid feeding machinery arm support above vertical driving motor, vertical to setIt puts, traversing driving motor is also connected with corresponding motor driver in driving module.
Laterally driven transmission system include it is traversing driving synchronous pulley, it is traversing driving synchronous belt, traversing driven synchronous pulley,Traversing vertical connecting rod, traversing swing arm, vertical slip transverse arm, traversing driving synchronous pulley are mounted on the shaft of traversing driving motorOn, traversing driving synchronous belt is socketed between traversing driving synchronous pulley and traversing driven synchronous pulley, traversing driven synchronous beltWheel is socketed on the vertical axis of reagent pipetting volume, and traversing driven synchronous pulley drives synchronous pulley in the same plane with traversing, traversingVertical connecting rod is elongated straight rod structure, and traversing vertical small end is fixed on the inside of the disk border of vertical driving synchronous pulley,The eccentric wheeling disk structure of composition drives traversing vertical connecting rod to be rotated with certain radius by the rotation of vertical driving synchronous pulley, intoAnd traversing swing arm is driven to rotate, traversing swing arm shape is oval strip slab construction, and the head end of traversing swing arm is connected by shaftIt on the bottom end platform of liquid feeding machinery arm support, can be rotated around the shaft at head end, the end of traversing swing arm is fixed with traversing hang downTo connecting rod, vertical slip transverse arm is strip slab construction, one end upper surface of vertical slip transverse arm and the vertical axis of reagent pipetting volumeLower face connection is fixed, and the upper surface of vertical slip transverse arm strip slab construction contacts and connects with the lower face of vertical axis palletConnect fixation, the other end of vertical slip transverse arm is vertically provided with open-work at center, and traversing vertical connecting rod is from open-workIn pass through, the vertical axis of reagent pipetting volume be circular shaft, be arranged at traversing driven synchronous pulley axle center by bearing arrangement, can be verticalDirection moves up and down, and the vertical axis lower end of reagent pipetting volume is fastened on vertical axis pallet.
Reagent pipetting volume transverse arm is horizontal cross plate structure, and the side of reagent pipetting volume transverse arm is fastened on the vertical axis of reagent pipetting volumeUpper end, other side are fixed with liquid transfer gun head carrier, and liquid feeding mechanical arm protective cover is plektron, lower openings, inner hollow, socketOn reagent pipetting volume transverse arm, liquid feeding machinery arm support is MULTILAYER COMPOSITE mechanism, is vertical driving motor, vertical driving power trainSystem, photoelectric sensor system, traversing driving motor, laterally driven transmission system, the vertical axis of reagent pipetting volume installation immobilization carrier, addThe installation of liquid machinery arm support is scheduled on the inside of casing lower half portion.
Specifically, horizontal displacement mechanism includes horizontal displacement driving motor, horizontal displacement synchronous belt, horizontal displacement synchronous beltTensioning wheel, horizontal displacement synchronous belt driving wheel, horizontal displacement synchronous belt tooth plate, horizontal displacement straight line slide unit, horizontal displacement stent,Horizontal displacement photoelectric sensor, horizontal displacement driving motor are mounted on horizontal displacement stent, and horizontal displacement driving motor also connectsThe respective drivers in driving module are connect, horizontal displacement synchronous belt is interior toothed timing, is socketed in the tensioning of horizontal displacement synchronous beltBetween wheel and horizontal displacement synchronous belt driving wheel, horizontal displacement synchronizes belt tensioner pulley and is mounted on horizontal displacement stent by shaftOn, mounting plane is consistent with plane where horizontal displacement synchronous belt driving wheel, and horizontal displacement synchronous belt driving wheel is mounted on levelOn the output revolving shaft of displacement drive motor, horizontal displacement synchronous belt tooth plate is the flat bed platform that can be fixed on synchronous belt, horizontalIt is fixed on horizontal displacement synchronous belt on the inside of displacement synchronous band tooth plate, on the fixed horizontal displacement straight line slide unit of outside installationHorizontal displacement slide unit ontology, horizontal displacement straight line slide unit include horizontal displacement slide unit ontology, horizontal displacement slide unit sliding block, horizontal positionShifting slide unit ontology is horizontal on horizontal displacement stent, and horizontal displacement slide unit sliding block can be acted in the band of horizontal displacement synchronous belt tooth plateIt is moved forward and backward, is also connect on horizontal displacement slide unit sliding block with vertical displacement pedestal upper end solid along horizontal displacement slide unit ontology with lowerFixed, horizontal displacement stent is slab construction, and the lower end of horizontal displacement stent connect fixation with casing internal, and horizontal displacement stent leads toIt crosses bolt nut structure and is fixedly connected with horizontal displacement driving motor, horizontal displacement synchronization belt tensioner pulley, horizontal displacement synchronous beltDriving wheel, horizontal displacement straight line slide unit, horizontal displacement photoelectric sensor include transmitting module, receiving module and signal condition mouldBlock, horizontal displacement photoelectric sensor by stent be mounted on horizontal displacement synchronous belt side, horizontal displacement photoelectric sensor withHorizontal displacement driving motor, horizontal displacement synchronous belt, horizontal displacement synchronizes belt tensioner pulley, horizontal displacement synchronous belt driving wheel is formedClosed-loop control system.
Vertical deviation mechanism include vertical displacement driving motor, vertical displacement synchronous belt, vertical displacement synchronize belt tensioner pulley,Vertical displacement synchronous belt driving wheel, vertical displacement synchronous belt tooth plate, vertical displacement straight line slide unit, vertical displacement stent, vertical positionPhotoelectric sensor, backplate are moved, vertical displacement driving motor is mounted on vertical displacement stent, and vertical displacement driving motor is also connected withThe respective drivers in module are driven, it is synchronous with vertical displacement that vertical displacement synchronous belt is socketed in vertical displacement synchronization belt tensioner pulleyBand driving wheel between, vertical displacement synchronize belt tensioner pulley by shaft be mounted on vertical displacement stent on, mounting plane with it is verticalPlane where displacement synchronous band driving wheel is consistent, and vertical displacement synchronous belt driving wheel is mounted on the output of vertical displacement driving motorIt in shaft, is fixed on vertical displacement synchronous belt on the inside of vertical displacement synchronous belt tooth plate, outside installation fixed vertical displacementVertical displacement slide unit ontology on straight line slide unit, vertical displacement straight line slide unit includes vertical displacement slide unit ontology, vertical displacement is slidedPlatform sliding block, vertical displacement slide unit ontology are vertically arranged on vertical displacement stent, and vertical displacement slide unit sliding block is same in vertical displacementIt is moved under drive of the step with tooth plate along vertical above and below vertical displacement slide unit ontology, vertical displacement pedestal upper end is fixed on horizontal displacementOn slide unit sliding block, it is same that vertical displacement stent by bolt nut structure is fixedly connected with vertical displacement driving motor, vertical displacementBelt tensioner pulley, vertical displacement synchronous belt driving wheel, vertical displacement straight line slide unit are walked, vertical displacement photoelectric sensor includes transmitting mouldBlock, receiving module and Signal-regulated kinase, vertical displacement photoelectric sensor are mounted on the side of vertical displacement synchronous belt by stentFace, the synchronous belt tensioner pulley of vertical displacement photoelectric sensor and vertical displacement driving motor, vertical displacement synchronous belt, vertical displacement,Vertical displacement synchronous belt driving wheel forms closed-loop control system, and backplate is laminar right angle angle bar, mounted on vertical displacement stentOn, positioned at vertical displacement driving motor, vertical displacement synchronous belt, vertical displacement synchronize belt tensioner pulley, vertical displacement synchronous belt drivesDriving wheel, vertical displacement synchronous belt tooth plate, vertical displacement straight line slide unit outside.
Sample is quantitatively handled up, and system includes sample plunger pump, sample-adding bar, sample are quantitatively handled up pipe-line system, sample plunger pumpComprising pump head and motor, sample plunger pump is fixed on instrument internal stent, and sample-adding bar is cylinder hollow structure, is loaded barHead end for pyramidal structure, sample-adding bar is fixed on vertical displacement slide unit sliding block, and sample quantitatively handles up pipe-line system for pipeRoad structure, sample quantitatively handle up pipe-line system head end connection sample-adding bar end outlet, sample quantitatively handles up pipe-line systemEnd connects sample plunger pump intake.
Tui Guan mechanisms include moving back pipe baffle ring, move back pipe baffle ring as circular ring structure, vertical displacement branch is fixed on by stentIt below frame, is socketed in above sample-adding bar, the diameter for moving back pipe baffle ring is more than the diameter of sample-adding bar.
Further, turntable synchronous belt, vertical driving synchronous belt, traversing driving synchronous belt, horizontal displacement synchronous belt, verticalDisplacement synchronous band is belt composition or chain structure.Turntable transport mechanism, vertical driving transmission system, laterally driven power trainSystem, horizontal displacement mechanism and vertical deviation mechanism are belt transmission or gear drive.
Further, turntable driving motor, traversing driving motor, horizontal displacement driving motor, vertical displacement driving motorFor one kind in stepper motor, servo motor or direct current generator, turntable driving motor shaft end is set by encoder.
Further, the quantitative plunger pump in reagent liquid-adding device, liquid transfer gun head carrier and liquid feeding pipe-line system are moreIt is a.
Further, the diameter and the number of teeth of the driven synchronous pulley of turntable transport mechanism turntable and turntable driving synchronous pulleyIt can adjust according to actual needs, also can adjust rotating speed tune of the turntable driving motor realization in rotary disc driving mechanism to sample turntableIt is whole.
Further, the sample cell bit array being made of three circle circular holes, three circle circular holes are respectively liquid relief from inner ring to outer ringRifle mouth slot array, specimen cup slot array, reaction cup slot array can also convert liquid-transfering gun mouth slot array, specimen cup slot according to demandThe position of array, reaction cup slot array.
Patent of the present invention does not only disclose a kind of fully-automatic intelligent urine iodine analyzer, but also including corresponding work sideMethod.The method of work of above-mentioned fully-automatic intelligent urine iodine analyzer, includes the following steps:
(1) communicating step:
1) staff sets working method in host computer computer.
2) host computer computer inputs staff instruction morphing, and passes through Serial Port Line and be transferred in communication module, andIt is finally-transmitted in controller.
3) running parameter of itself, state and the sensing data of acquisition are transferred to by controller energy communication control moduleHost computer computer, the parameter received and data are checked for staff, is analyzed, is stored for host computer computer and decision.
(2) test sample addition step:
1) placing response is used on reaction cup slot array of the staff in the outermost sample cell bit array of sample turntableTest tube, place specimen bottle in intermediate specimen cup slot array, placed on the liquid-transfering gun mouth slot array of innermost ring cleanSuction nozzle sets relevant parameter in host computer computer and starts machine.
2) controller control driving module driving disc driving motor rotation drives sample turntable by turntable transport mechanismRotation drives the pending reagent sample of first row to rotate to designated position.
3) the horizontal displacement mechanism and vertical deviation machine in controller control driving module driving sample integrated treatment mechanismStructure moves, and sample-adding bar is driven to move to right over liquid-transfering gun mouth slot array.
4) the vertical deviation mechanism in controller control driving module driving sample integrated treatment mechanism moves downward, and drivesSample-adding bar continues to move downward, and is loaded bar and suction nozzle thereon is inserted into inside suction nozzle clean on liquid-transfering gun mouth slot array, completeSuction nozzle function is installed.
5) the horizontal displacement mechanism and vertical deviation machine in controller control driving module driving sample integrated treatment mechanismStructure moves, and the sample-adding bar for being inserted with clean suction nozzle is driven to move to right over pending specimen cup slot array.
6) the vertical deviation mechanism in controller control driving module driving sample integrated treatment mechanism moves downward, and drivesSample-adding bar moves downward, and the suction nozzle on sample-adding bar is driven to be inserted into specimen cup slot array inside sample to be tested, and controller control is fixedAmount fixed point liquid feeding system acting, draws a certain amount of liquid to be tested.
7) the horizontal displacement mechanism and vertical deviation machine in controller control driving module driving sample integrated treatment mechanismStructure moves, and the suction nozzle that driving the suction on sample-adding bar has testing liquid moves to the reaction examination of pending first row reaction cup slot arrayThe surface of pipe.
8) quantitatively a certain amount of liquid to be tested of fixed point liquid feeding system discharge to pending first row tests examination for controller controlGuan Zhong completes test sample out of test tube on specimen cup slot array to the invisible spectro addition on reaction cup slot array.
(3) auxiliary reagent addition step:
1) it is pollution-free that color developing agent of the staff on liquid transfer gun head carrier is loaded bar, oxidant is loaded installation two on barCompletely new suction nozzle.
2) in above-mentioned sample adding procedure, controller control driving module driving disc driving motor is rotated further, and is led toIt crosses turntable transport mechanism and drives the rotation of sample turntable, the pending reagent sample of first row is driven to rotate to designated position.
3) controller control driving module drives traversing driving motor and then drives laterally driven transmission system action, drivesColor developing agent sample-adding bar, oxidant sample-adding bar on liquid transfer gun head carrier on reagent pipetting volume transverse arm and rifle mouth thereon add around reagentThe vertical axis of sample is rotated to reagent adding trough.
4) controller control driving module drives vertical driving motor rotation, and liquid relief is driven by vertical driving transmission systemColor developing agent sample-adding bar, oxidant sample-adding bar on pipette tips carrier and suction nozzle thereon decline and are inserted into auxiliary reagent pond.
5) controller control quantitatively fixed point liquid feeding system work so that two suction nozzles on liquid transfer gun head carrier are quantitative respectivelyFixed point draws a certain amount of auxiliary reagent.
6) controller control driving module drives vertical driving motor rotation, and liquid relief is driven by vertical driving transmission systemThe suction nozzle that color developing agent sample-adding bar, oxidant sample-adding bar and suction on pipette tips carrier have reagent rises and leaves auxiliary reagent pond.
7) as needed, controller control driving module drives traversing driving motor and then drives laterally driven transmission systemAction drives the suction nozzle on the color developing agent sample-adding bar on the liquid transfer gun head carrier on reagent pipetting volume transverse arm around the vertical axis of reagent pipetting volumeIt rotates to the reaction tube on reaction cup slot array to be measured.
8) controller control quantitatively fixed point liquid feeding system work so that on the color developing agent sample-adding bar on liquid transfer gun head carrierSuction nozzle quantitatively pinpoints a certain amount of auxiliary reagent that spues.
9) as needed, controller control driving module drives traversing driving motor and then drives laterally driven transmission systemAction drives the suction nozzle on the oxidant sample-adding bar on the liquid transfer gun head carrier on reagent pipetting volume transverse arm around the vertical axis of reagent pipetting volumeRotation realize position micro-shifting, by oxidant be loaded bar on suction nozzle be moved to the reaction tube on reaction cup slot array to be measured just onSide.
10) controller control quantitatively fixed point liquid feeding system work so that on liquid transfer gun head carrier on oxidant sample-adding barSuction nozzle quantitatively pinpoints a certain amount of auxiliary reagent that spues, and addition auxiliary reagent operation is so far completed in sample to be tested test tube.
11) controller control control driving module drives vertical driving motor rotation, passes through vertical driving transmission system bandColor developing agent sample-adding bar, oxidant sample-adding bar on dynamic liquid transfer gun head carrier set back, and complete primary sample-adding operation.
(4) test sample whipping step:
1) after completing auxiliary reagent addition operation, controller control driving module driving disc driving motor rotation passes throughTurntable transport mechanism drives the rotation of sample turntable, and the pending reagent sample tube for being added to auxiliary reagent is driven to rotate to specifiedPosition.
2) the horizontal displacement mechanism and vertical deviation machine in controller control driving module driving sample integrated treatment mechanismStructure moves, and the sample-adding bar for being inserted with suction nozzle is driven to move to right over the reaction cup test tube in specimen cup slot array.
3) the vertical deviation mechanism in controller control driving module driving sample integrated treatment mechanism moves downward, and drivesSample-adding bar and suction nozzle thereon move downward, and the suction nozzle on sample-adding bar is driven to be inserted into the reaction cup test tube in specimen cup slot arrayIn.
4) quantitatively fixed point liquid feeding system draws a certain amount of sample liquid to be tested for controller control.
5) the vertical deviation mechanism in controller control driving module driving sample integrated treatment mechanism moves upwards, and drivesSample-adding bar and suction nozzle thereon move upwards and leave reaction cup test tube rim of a cup a distance in specimen cup slot array.
6) controller control quantitatively pinpoints liquid feeding system discharge all liquid to be tested, so far completes once to specimen cup slotLiquid mixing in reaction cup test tube in array.
7) 3) -6 are repeated the above steps) once, second is completed to the liquid in the reaction cup test tube in specimen cup slot arrayBody mixed function.
8) as needed be repeated twice and above-mentioned steps 3 more than twice) -6), realize to liquid in test tube to be measuredUniformly mixing.
(5) pipe step is moved back:
1) after controller, which controls, completes test sample addition and hybrid manipulation, controller control driving module driving sampleHorizontal displacement mechanism and vertical deviation mechanism kinematic in integrated treatment mechanism drive the sample-adding bar for being inserted with suction nozzle to move to waste productRight over slot.
2) the vertical deviation mechanism in controller control driving module driving sample integrated treatment mechanism continues up,Sample-adding bar and suction nozzle thereon is driven to move upwards, until suction nozzle, which is topmost touched in Tui Guan mechanisms, moves back pipe baffle ring, at this timeSuction nozzle is moved back pipe baffle ring and is backed off, and is fallen into waste product slot, and pipe operation is moved back in completion.
(6) urine iodine concentration step is calculated:
1) controller control driving module driving disc driving motor rotation drives sample turntable by turntable transport mechanismRotation drives the reaction cup test tube being added on the reaction cup slot array of test agent between light path detection module.
2) controller controls special LED operation, and silicon light is reached through colorimetric pool, test sample test tube, liquid to be testedIn diode.
3) controller control silicon photo diode work, receives the light of specific wavelength and senses intensity of illumination, controller rootUrine iodine concentration is calculated according to intensity of illumination.
The invention has the advantages that:The fully-automatic intelligent urine iodine analyzer of the present invention is led to using Quantitative colorimetric methodCross the point-to-point operation that classes of agents is realized in control reagent disc rotation;It is realized by using sample-adding agitating device to test agentMixing avoids sample cross contamination, improves mixing efficiency;Color developing agent and oxidant are realized by using double reagent needle sample armFunction is added, shortens detection time, saves equipment inside and outside space;Have automatic interpretation result, automatic printing function of reporting, carryHeight urine iodine detects the degree of automation, efficiently avoids error caused by being loaded by hand, improves urine examination accuracy of detection and detection is imitatedRate reduces testing cost.
Description of the drawings
Fig. 1 is the dimensional structure diagram of fully-automatic intelligent urine iodine analyzer of the present invention.
Fig. 2 is that fully-automatic intelligent urine iodine analyzer complete machine of the present invention removes the entirety perspective view after casing.
Fig. 3 is that fully-automatic intelligent urine iodine analyzer complete machine of the present invention removes the whole main structure diagram after casing.
Fig. 4 is that fully-automatic intelligent urine iodine analyzer complete machine of the present invention removes the whole left view structural representation after casing.
Fig. 5 is that fully-automatic intelligent urine iodine analyzer complete machine of the present invention removes the whole right side structural representation after casing.
Fig. 6 is that fully-automatic intelligent urine iodine analyzer complete machine of the present invention removes the whole backsight structural representation after casing.
Fig. 7 is that fully-automatic intelligent urine iodine analyzer complete machine of the present invention removes the whole overlooking the structure diagram after casing.
Fig. 8 is the partial enlargement structural representation of the reagent liquid-adding device of fully-automatic intelligent urine iodine analyzer of the present invention.
Fig. 9 is that fully-automatic intelligent urine iodine analyzer of the present invention removes the main structure diagram after casing and backplate.
Figure 10 is that fully-automatic intelligent urine iodine analyzer of the present invention removes the left view structural representation after casing and backplate.
Figure 11 is that fully-automatic intelligent urine iodine analyzer of the present invention removes the right side structural representation after casing and backplate.
Figure 12 is fully-automatic intelligent urine iodine analyzer complete machine main structure diagram of the present invention.
Figure 13 is fully-automatic intelligent urine iodine analyzer complete machine left view structural representation of the present invention.
Figure 14 is fully-automatic intelligent urine iodine analyzer complete machine right side structural representation of the present invention.
Figure 15 is fully-automatic intelligent urine iodine analyzer complete machine overlooking the structure diagram of the present invention.
Figure 16 is fully-automatic intelligent urine iodine analyzer complete machine backsight structural representation of the present invention.
Figure 17 is the dimensional structure diagram of upper computer control system in fully-automatic intelligent urine iodine analyzer of the present invention.
Specific embodiment
The following is specific embodiments of the present invention, and technical scheme of the present invention is described further, but the present inventionProtection domain is not limited to these embodiments.It is every to be included in the present invention without departing substantially from the change of present inventive concept or equivalent substituteProtection domain within.
As shown in Fig. 1-17, a kind of fully-automatic intelligent urinates iodine analyzer, including casing 100, sample carriers mechanism 200, examinationAgent liquid-adding device 300, light path detection 400, sample integrated treatment mechanism 500, waste product slot 600 and electric-control system 700, casing100 include top half and lower half portion, and casing 100 is alloy material, and outside is painted to improve insulation and anti-static function, underHalf portion is divided into rectangular parallelepiped structure, and rear side sets removable end cap to facilitate maintenance overhaul, and top half is according to reagent integrated treatment500 appearance profile of mechanism sets to realize the defencive function to internal executing agency etc..Sample synthesis is provided in top halfProcessing mechanism 500, lower half portion are equipped with sample carriers mechanism 200, reagent liquid-adding device 300, light path detection 400, sampleIntegrated treatment mechanism 500, waste product slot 600 and electric-control system 700, the upper surface of the lower half portion of casing 100 are provided with reagent and addAdd slot 110, the side of casing 100 is equipped with power interface 120, communication interface 130, thermovent 140 and power switch 150.
Sample carriers mechanism 200 includes sample turntable 210, turntable transport mechanism 220, rotary disc driving mechanism 230.Sample turnsDisk 210 includes turntable disk body 211, sample cell bit array 212, shaft open-work 213, test tube support disk body 214, specimen cup slot positionArray 215 is supported, turntable disk body 211 is with certain thickness disc structure, is arranged on the upper surface of 100 lower half portion of casingOn, three circle circular holes are uniformly distributed on turntable disk body 211, Circularhole diameter is slightly coarser than reagent pipe diameter, and the circular hole often enclosed is along turntableDisk body 211 is radially consistent, every group of radially aligned distribution of corresponding three circular holes, and the array of three circle circular hole compositions is sample cell positionArray 212, three circle circular holes are respectively from inner ring to outer ring:Liquid-transfering gun mouth slot array 212-a, specimen cup slot array 212-b, reactionLiquid relief rifle mouth, specimen cup slot array 212-b, reaction cup slot are placed on cup slot array 211-c, liquid-transfering gun mouth slot array 212-aArray 211-c then places sample tube and reaction test tube respectively, and turntable disk body 211 is provided centrally with the through-hole of major diameter, isShaft open-work 213, to install turntable bearing 221.Support array in specimen cup slot position is provided on test tube support disk body 214215, specimen cup slot position support array 215 is corresponded with 212 position of sample cell bit array, and sample cell bit array 212 is in test tubeIt is set on support disk body 214, totally three circles, the slot position often enclosed is radially consistent along test tube support disk body 214, every group of corresponding three slotThe radially aligned distribution in position, each slot position shape in specimen cup slot position support array 215 are pyramidal structure, it can be achieved to be measuredThe supporting role of test tube.Test tube support disk body 214 is fixed on 211 lower end of turntable disk body, passes through stent and turntable disk body211 connect and fix, and rotated together with turntable disk body 211.The allomeric function of sample turntable 210 is:Pass through turntable disk body211st, sample cell bit array 212, test tube support disk body 214 and specimen cup slot position support array 215 form and sample to be tested are testedRequired utensil (liquid-transfering gun mouth, specimen cup test tube, reaction cup test tube etc.) provides support and holds carrier platform, while sets and turnAxis open-work 213 is placing waste product slot 600.
Turntable transport mechanism 220 includes turntable bearing 221, shaft 222, the driven synchronous pulley 223 of turntable, turntable driving togetherWalk belt wheel 224, turntable synchronous belt 225, the inner ring lower end connection shaft 222 of turntable bearing 221, the fixed turntable of inner ring upper end connectionDisk body 211 and test tube support disk body 214, the outer shroud of turntable bearing 221 are fastened on instrument support, and 222 bottom end of shaft is setThe driven synchronous pulley 223 of turntable is equipped with, the driven synchronous pulley 223 of turntable drives synchronous belt by turntable synchronous belt 225 and turntable224 connection of wheel, turntable driving synchronous pulley 224 are arranged on turntable driving motor 231, pass through the drive of turntable driving motor 231It is dynamic that turntable driving synchronous pulley 224 is driven to rotate.220 allomeric function of turntable transport mechanism is:Turntable driving motor 231 drivesTurntable drives synchronous pulley 224, realizes that driven synchronous pulley 223 drives, and then with turn to turntable by turntable synchronous belt 225Axis 222 rotates, the final driving function realized to turntable disk body 211 and test tube support disk body 214.
Rotary disc driving mechanism 230 includes turntable driving motor 231, turntable driving motor stent 232, turntable driving motor branch232 bottom of frame is fixed on instrument, and turntable driving motor 231 is mounted on turntable driving motor stent 232, turntable driving electricityThe output revolving shaft of machine 231 is fixed at 224 axle center of turntable driving synchronous pulley, and turntable driving motor 231 is also connected with drivingCorresponding motor driver in module 712.230 allomeric function of rotary disc driving mechanism is:Realize consolidating to turntable driving motor 231It is fixed, and driving disc drives synchronous pulley 224 and drives and subsequently links structure operating.
Reagent liquid-adding device 300 includes reagent pipetting volume mechanical arm 310, quantitatively fixed point liquid feeding system 320.Reagent pipetting volume machineryArm 310 includes vertical driving motor 311, vertical driving transmission system 312, photoelectric sensor system 313, traversing driving motor314th, the vertical axis 316 of laterally driven transmission system 315, reagent pipetting volume, reagent pipetting volume transverse arm 317, liquid feeding mechanical arm protective cover318th, liquid feeding machinery arm support 319.
Vertical driving motor 311 is fixed on 319 downside of liquid feeding machinery arm support, the vertical connection of driving motor 311 driving mouldCorrespondence motor driver in group 712.Vertical driving transmission system 312 includes vertical driving and synchronizes belt tensioner pulley 312-a, hangs downTo driving synchronous belt 312-b, vertical driving synchronous pulley 312-c, vertical driving synchronous belt tooth plate 312-d, vertical axis pallet312-e, vertical driving synchronous pulley 312-c are mounted on the output revolving shaft of vertical driving motor 311, vertical driving synchronous beltBearing up pulley 312-a is mounted remotely from vertical driving synchronous pulley 312-c sides by shaft, and vertical driving synchronizes belt tensioner pulley312-a and vertical driving synchronous pulley 312-c is in approximately the same plane, and axle axis is parallel, vertical driving synchronous pulley312-c is sleeved on the vertical axis 316 of reagent pipetting volume, is connect, and the vertical axis of reagent pipetting volume by bearing axis 316 vertical with reagent pipetting volume316 can move up and down in the bearing at vertical driving synchronous pulley 312-c axle center, in vertical driving synchronous belt tooth plate 312-dSide is fixed on vertical driving synchronous belt 312-b, the component that outside installation need to drive, vertical driving synchronous belt tooth plate 312-D is also connected with being fixed on vertical axis pallet 312-e, and vertical axis pallet 312-e shapes are semicircle slab construction, are passed through at axle centerThe lower end of bearing axis 316 vertical with reagent pipetting volume connect fixation, and side connect and consolidates with vertical driving synchronous belt tooth plate 312-dFixed, the vertical axis 316 of reagent pipetting volume can rotate, and move up slip with vertical axis pallet 312-e around vertical axis pallet 312-e.It is verticalDriving transmission system 312 allomeric function be:Realize driving force from vertical driving synchronous pulley 312-c to vertical driving synchronous beltThe transmission effect of the vertical driving synchronous belt tooth plate 312-d of 312-b most Zhongdao, it is vertical so as to fulfill axis 316 vertical to reagent pipetting volumeDirection moves up and down.
Photoelectric sensor system 313 is photoelectric sensor, including transmitting module, receiving module and Signal-regulated kinase, totally twoSet is mounted on the side of vertical driving synchronous belt 312-b and traversing driving synchronous belt 315-b by stent respectively, can be real respectivelyNow to the micro-displacement signal detection of vertical driving synchronous belt 312-b and traversing driving synchronous belt 315-b, thus with vertical drivingMotor 311, vertical driving transmission system 312 and traversing driving motor 314, laterally driven transmission system 315 form closed-loop controlSystem increases control accuracy.Traversing driving motor 314 is fixed on the instrument liquid feeding machinery of vertical 311 top of driving motorOn arm support 319, vertical setting, traversing driving motor 314 is also connected with corresponding motor driver in driving module 712.
Laterally driven transmission system 315 includes traversing driving synchronous pulley 315-a, traversing driving synchronous belt 315-b, traversingDriven synchronous pulley 315-c, traversing vertical connecting rod 315-d, traversing swing arm 315-e, vertical slip transverse arm 315-f, traversing drivingSynchronous pulley 315-a is mounted in the shaft of traversing driving motor 314, and traversing driving synchronous belt 315-b is socketed in traversing drivingBetween synchronous pulley 315-a and traversing driven synchronous pulley 315-c, traversing driven synchronous pulley 315-c is socketed in reagent pipetting volumeOn vertical axis 316, traversing driven synchronous pulley 315-c drives synchronous pulley 315-a in the same plane with traversing, traversing driveThe length of dynamic the distance between synchronous pulley 315-a and traversing driven synchronous pulley 315-c and traversing driving synchronous belt 315-bIt is related.Traversing vertical connecting rod 315-d is elongated straight rod structure, and traversing vertical connecting rod 315-d upper ends are fixed on vertical driving and synchronizeOn the inside of the disk border of belt wheel 312-c, eccentric wheeling disk structure is formed, is driven by the rotation of vertical driving synchronous pulley 312-cTraversing vertical connecting rod 315-d is rotated with certain radius, and then drives traversing swing arm 315-e rotations, traversing vertical connecting rod 315-dIt primarily serves power and transmits function vector, rotary driving force is transferred to traversing swing arm from vertical driving synchronous pulley 312-cOn 315-e.Traversing swing arm 315-e shapes are oval strip slab construction, and the head end of traversing swing arm 315-e is connected to by shaftOn the bottom end platform of liquid feeding machinery arm support 319, it can be rotated around the shaft at head end, the end of traversing swing arm 315-e is fixed withTraversing vertical connecting rod 315-d, by the rotation of traversing vertical connecting rod 315-d, so as to which traversing swing arm 315-e be driven to turn around its endShaft rotation is moved, and plays the role of the traversing vertical connecting rod 315-d of support.Vertical slip transverse arm 315-f be strip slab construction, vertical cunningThe lower face of one end upper surface axis 316 vertical with reagent pipetting volume of dynamic transverse arm 315-f connect fixation, and vertical slip transverse arm 315-The upper surface of f strip slab constructions contacts with the lower face of vertical axis pallet 312-e and connects fixation.Vertical slip transverse arm 315-The other end of f is vertically provided with open-work at center, and open-work diameter is slightly larger than traversing vertical connecting rod 315-d, and horizontalVertical connecting rod is moved to pass through from above-mentioned open-work, it is upper on traversing vertical connecting rod 315-d so as to fulfill vertical slip transverse arm 315-fLower slider function;In addition when traversing vertical connecting rod 315-d is axis rotation with the vertical axis 316 of reagent pipetting volume, drive can be passed throughVertical slip transverse arm 315-f rotations, and then vertical axis pallet 312-e rotations are driven, so as to drive 316 turns of the vertical axis of reagent pipetting volumeIt is dynamic.The major function of laterally driven transmission system 315 is:By the gearing of traversing driving synchronous belt 315-b, by traversing driveThe driving force of dynamic synchronous pulley 315-a is transferred on traversing vertical connecting rod 315-d, and then drives vertical slip transverse arm 315-f pendulumDynamic, final realize drives vertical 316 rotating function of axis of reagent pipetting volume.
The vertical axis 316 of reagent pipetting volume is circular shaft, and traversing driven synchronous pulley 315-c axle center is arranged on by bearing arrangementPlace lower in vertical direction can move, and vertical 316 lower end of axis of reagent pipetting volume is fastened on vertical axis pallet 312-e.ReagentIt is loaded vertical axis 316 and relies primarily on traversing driving synchronous pulley 315-a → traversing driving synchronous belt 315-b → traversing driven synchronizationBelt wheel 315-c → vertical axis 316 of → traversing vertical connecting rod 315-d → vertical slip transverse arm 315-f → reagent pipetting volume realizes rotationFunction;The vertical axis 316 of reagent pipetting volume rely primarily on vertical driving synchronous pulley 312-c → vertical driving synchronous belt 312-b → hang downUp and down motion function is realized to the vertical axis 316 of driving synchronous belt tooth plate 312-d → vertical axis pallet 312-e → reagent pipetting volume.AndIn above-mentioned rotation and locomotive function, due to adding in vertical axis pallet 312-e, traversing swing arm 315-e and vertical slip transverse arm 315-fSo as to fulfill the decoupling function of two kinds of operation forms, i.e. horizontal movement and vertical movement is non-interference.
Reagent pipetting volume transverse arm 317 is horizontal cross plate structure, and the side of reagent pipetting volume transverse arm 317 is fastened on reagent pipetting volumeVertical 316 upper end of axis, other side are fixed with liquid transfer gun head carrier 322, play the vertical axis 316 of connection reagent pipetting volume and liquid-transfering gunThe effect of head carrier 322.Liquid feeding mechanical arm protective cover 318 be plektron, lower openings, inner hollow, be socketed in reagent pipetting volume horizontal strokeOn arm 317, realize to the exposed reagent pipetting volume transverse arm 317 outside instrument and vertical 316 defencive function of axis of reagent pipetting volume.
Liquid feeding machinery arm support 319 is MULTILAYER COMPOSITE mechanism, is vertical driving motor 311, vertical driving transmission system312nd, the peace of the vertical axis 316 of photoelectric sensor system 313, traversing driving motor 314, laterally driven transmission system 315, reagent pipetting volumeImmobilization carrier is filled, the installation of liquid feeding machinery arm support 319 is scheduled on the inside of 100 lower half portion of casing.
The allomeric function of reagent pipetting volume mechanical arm 310 is:Vertical driving motor 311 is by driving vertical driving transmission system312 realize the vertical driving of the vertical axis 316 to reagent pipetting volume, and traversing driving motor 314 is by driving laterally driven transmission system315 realize to reagent pipetting volume vertical axis 316 it is laterally driven.Photoelectric sensor system 313 then can be achieved to vertical driving motor311st, vertical driving transmission system 312 and traversing driving motor 314, laterally driven transmission system 315 form closed-loop control system,Increase control accuracy.Reagent pipetting volume transverse arm 317 realizes the rising of drive external equipment and rotation by connecting the vertical axis 316 of reagent pipetting volumeTranshipment is dynamic, thus by oxidant and color developing agent to be added in liquid transfer gun head carrier 322 and its liquid transfer gun head and pipette tips of insideIt is transferred to 210 suitable position of sample turntable.
Quantitatively fixed point liquid feeding system 320 includes quantitative plunger pump 321, liquid transfer gun head carrier 322, liquid feeding pipe-line system 323,Quantitative plunger pump 321, liquid transfer gun head carrier 322, liquid feeding pipe-line system 323 are two sets, and liquid feeding pipe-line system 323 is common tubeRoad system, connects quantitative plunger pump 321 and liquid transfer gun head carrier 322 respectively, and quantitative plunger pump 321 is fixed on instrument internalOn stent, including color developing agent quantitative plunger pump 321-a and oxidant quantitative plunger pump 321-b, liquid transfer gun head carrier 322 includes aobviousToner sample-adding bar 322-a, oxidant sample-adding bar 322-b, it is aobvious by the connection of liquid feeding pipe-line system 323 that color developing agent is loaded bar 322-aThe entrance of toner quantitative plunger pump 321-a, oxidant are loaded bar 322-b and are quantified by the connection oxidant of liquid feeding pipe-line system 323The entrance of plunger pump 321-b.Liquid transfer gun head carrier 322, which is mainly realized, inserts liquid transfer gun head function, while also controllable liquid-transfering gunHead is drawn by the liquid in oxidant pond and color developing agent pond and discharge function.Liquid feeding pipe-line system 323 realizes liquid or gasThe Pipe transfer function of body.
The comprehensive function of reagent liquid-adding device 300 is:It is realized by quantitative fixed point liquid feeding system 320 to external oxidant pondWith the reagent absorption in color developing agent pond, reagents sample-adding mechanical arm 310 realizes that the pipette tips by required liquid feeding are transferred to sample and turnThe addition function of the color developing agent and oxidant to test agent is realized in 210 suitable position of disk.
Light path detection 400 includes colorimetric carrier 410, light path detection module 420, and colorimetric carrier 410 includes colorimetric pool411st, hood 412, colorimetric pool pillar 413, colorimetric pool 411 are two layers inside and outside annular, can be put between two layers inside and outside colorimetric pool 411Test tube is put, the corresponding sample cell bit array 212 of outermost layer is corresponding with the annulate lamella of colorimetric pool 411 on turntable disk body 211, colorimetric pool411 light for primarily serving through specific wavelength are allowed to reach on testing liquid, realize that relevant parameter measures.Hood 412 is ringShape sector structure, bottom hollow out, above the corresponding sample cell bit array 212 of outermost layer on turntable disk body 211, hood412 are fixed on the upper surface of 100 lower half portion of casing of 420 top of light path detection module, play and detect mould for light path420 shaded effect of block improves light path detection module 420 and detects accurately.Colorimetric pool pillar 413 is elongated stanchions, and quantity is four,413 upper end of colorimetric pool pillar is fixed with colorimetric pool 411, and lower end is fixed on casing 100, is played as light path detection module420 shaded effects improve light path detection module 420 and detect accurately.Light path detection module 420 include special light emitting diode 421,Silicon photo diode 422, special light emitting diode 421 are the diode that can send out specific wavelength, and special light emitting diode 421 is setIt puts in the outside of 411 cyclic structure of colorimetric pool, close to 412 lower section of hood, special light emitting diode 421 is also connected with controller711, realize being switched on and off for controllability.Silicon photo diode 422 is particular diode, is subjected to the illumination of specific wavelength, togetherWhen can sense the illumination of varying strength, according to the luminous absorption degree from special light emitting diode 421 of reception, so as to calculate iodineConcentration.Silicon photo diode 422 is mounted on the opposite of special light emitting diode 421, in the inside of 411 cyclic structure of colorimetric pool,Silicon photo diode 422 uses in pairs with special light emitting diode 421, between special light emitting diode 421 and silicon photo diode 422Light path transmitting and receive by colorimetric pool 411.Silicon photo diode 422 is connected with controller 711.Light path detection module 420Allomeric function be:Emit the light of specific wavelength by special light emitting diode 421, after colorimetric pool 411, into silicon lightDiode 422, silicon photo diode 422 can experience intensity of illumination, so as to calculate the concentration of iodine according to the degree of absorption of light, by signalIt send to controller 711 and analyzes and processes.
The comprehensive function of light path detection 400 is:Testing liquid passes through particular organization (colorimetric pool 411), passes through light pathDetection module 420, which is realized, measures the iodine concentration by the liquid in colorimetric pool 411.
Sample integrated treatment mechanism 500 includes horizontal displacement mechanism 510, vertical deviation mechanism 520, sample and quantitatively handles up and beSystem 530, Tui Guan mechanisms 540, horizontal displacement mechanism 510 include horizontal displacement driving motor 511, horizontal displacement synchronous belt 512,Horizontal displacement synchronizes belt tensioner pulley 513, horizontal displacement synchronous belt driving wheel 514, horizontal displacement synchronous belt tooth plate 515, horizontal positionMove straight line slide unit 516, horizontal displacement stent 517, horizontal displacement photoelectric sensor 518.Horizontal displacement driving motor 511 is mounted onOn horizontal displacement stent 517, horizontal displacement driving motor 511 is also connected with the respective drivers in driving module 712.Horizontal displacementSynchronous belt 512 is interior toothed timing, is socketed in horizontal displacement and synchronizes belt tensioner pulley 513 and horizontal displacement synchronous belt driving wheel 514Between, the length belt tensioner pulley 513 synchronous with horizontal displacement and horizontal displacement synchronous belt driving wheel of horizontal displacement synchronous belt 512The distance between 514 is related.Horizontal displacement synchronizes belt tensioner pulley 513 and is mounted on horizontal displacement stent 517 by shaft, installationPlane is consistent with 514 place plane of horizontal displacement synchronous belt driving wheel, and horizontal displacement synchronous belt driving wheel 514 is mounted on horizontal positionIt moves on the output revolving shaft of driving motor 511.Horizontal displacement synchronous belt tooth plate 515 is the flat bed platform that can be fixed on synchronous belt,515 inside of horizontal displacement synchronous belt tooth plate is fixed on horizontal displacement synchronous belt 512, and the portion that need to be driven then is installed in outsidePart is in the present invention the horizontal displacement slide unit ontology 516-a on fixed horizontal displacement straight line slide unit 516.Horizontal displacement straight lineSlide unit 516 includes horizontal displacement slide unit ontology 516-a, horizontal displacement slide unit sliding block 516-b, horizontal displacement slide unit ontology 516-aIt is horizontal on horizontal displacement stent 517, horizontal displacement slide unit sliding block 516-b can be in the drive of horizontal displacement synchronous belt tooth plate 515Be moved forward and backward under effect along horizontal displacement slide unit ontology 516-a, on horizontal displacement slide unit sliding block 516-b also with vertical displacement stentThe connection of 527 upper ends is fixed.Horizontal displacement stent 517 is slab construction, the lower end of horizontal displacement stent 517 with inside casing 100Connection is fixed, and horizontal displacement stent 517 is fixedly connected with horizontal displacement driving motor 511, horizontal position by bolt nut structureSynchronous belt tensioner pulley 513, horizontal displacement synchronous belt driving wheel 514, horizontal displacement straight line slide unit 516 are moved, realizes that support platform is madeWith.Horizontal displacement photoelectric sensor 518 includes transmitting module, receiving module and Signal-regulated kinase, horizontal displacement photoelectric sensingDevice 518 is mounted on the side of horizontal displacement synchronous belt 512 by stent, realizes the micro-displacement to horizontal displacement synchronous belt 512Signal detection, horizontal displacement photoelectric sensor 518 and horizontal displacement driving motor 511, horizontal displacement synchronous belt 512, horizontal positionMove synchronous belt tensioner pulley 513, horizontal displacement synchronous belt driving wheel 514 forms closed-loop control system.Horizontal displacement mechanism 510Allomeric function is:Horizontal displacement driving motor 511 is tensioned by horizontal displacement synchronous belt driving wheel 514, horizontal displacement synchronous beltWheel 513 realizes that the rotation to horizontal displacement synchronous belt 512 drives, horizontal so as to which horizontal displacement synchronous belt tooth plate 515 be driven to slideDisplacement synchronous can then be driven with tooth plate 515 in horizontal displacement straight line slide unit 516 horizontal displacement slide unit sliding block 516-b (and itsOn other subsidiary bodies:Vertical displacement stent 527) it is moved forward and backward.In the process, horizontal displacement photoelectric sensor 518 is thenThe micro-displacement signal detection to horizontal displacement synchronous belt 512 can be achieved, improve system control accuracy.
Vertical deviation mechanism 520 includes vertical displacement driving motor 521, vertical displacement synchronous belt 522, vertical displacement synchronizationBelt tensioner pulley 523, vertical displacement synchronous belt driving wheel 524, vertical displacement synchronous belt tooth plate 525, vertical displacement straight line slide unit526th, vertical displacement stent 527, vertical displacement photoelectric sensor 528, backplate 529.Vertical displacement driving motor 521, which is mounted on, to hang downOn straight displacement stent 527, vertical displacement driving motor 521 is also connected with the respective drivers in driving module 712, and vertical displacement is sameStep band 522 is interior toothed timing, be socketed in vertical displacement synchronize belt tensioner pulley 523 and vertical displacement synchronous belt driving wheel 524 itBetween, the length of vertical displacement synchronous belt 522 belt tensioner pulley 523 synchronous with the vertical displacement and vertical displacement synchronous belt driving wheelThe distance between 524 is related.Vertical displacement synchronizes belt tensioner pulley 523 and is mounted on vertical displacement stent 527 by shaft, installationPlane is consistent with 524 place plane of vertical displacement synchronous belt driving wheel, and vertical displacement synchronous belt driving wheel 524 is mounted on vertical positionIt moves on the output revolving shaft of driving motor 521,525 inside of vertical displacement synchronous belt tooth plate is fixed on vertical displacement synchronous beltOn 522, the component that need to be driven then is installed in outside, in the present invention, the vertical position on installation fixed vertical displacement straight line slide unit 526Move slide unit ontology 526-a.Vertical displacement straight line slide unit 526 includes vertical displacement slide unit ontology 526-a, vertical displacement slide unit sliding block526-b, vertical displacement slide unit ontology 526-a are vertically arranged on vertical displacement stent 527, vertical displacement slide unit sliding block 526-bIt is moved under the drive of vertical displacement synchronous belt tooth plate 525 along above and below vertical displacement slide unit ontology 526-a is vertical, vertical displacement is slidedSample-adding bar 532 is mounted on platform sliding block 526-b, before sample-adding bar 532 being driven to carry out by vertical displacement slide unit sliding block 526-bAfter move.527 upper end of vertical displacement stent is fixed on horizontal displacement slide unit sliding block 516-b, and vertical displacement stent 527 passes through spiral shellBolt nut structure is fixedly connected with vertical displacement driving motor 521, vertical displacement synchronizes belt tensioner pulley 523, vertical displacement synchronizesBand driving wheel 524, vertical displacement straight line slide unit 526, vertical displacement photoelectric sensor 528 include transmitting module, receiving module andSignal-regulated kinase, vertical displacement photoelectric sensor 528 are mounted on the side of vertical displacement synchronous belt 522 by stent, realizeTo the micro-displacement signal detection of vertical displacement synchronous belt 522, vertical displacement photoelectric sensor 528 and vertical displacement driving motor521st, vertical displacement synchronous belt 522, vertical displacement synchronize belt tensioner pulley 523, the composition closed loop of vertical displacement synchronous belt driving wheel 524Control system, backplate 529 are laminar right angle angle bar, and length is consistent with vertical deviation mechanism 520, mounted on vertical displacement stentOn 527, positioned at 520 front side of vertical deviation mechanism, to vertical displacement driving motor 521, vertical displacement synchronous belt 522, vertical positionMove synchronous belt tensioner pulley 523, vertical displacement synchronous belt driving wheel 524, vertical displacement synchronous belt tooth plate 525, vertical displacement straight line526 grade transmission parts of slide unit shield.The allomeric function of vertical deviation mechanism 520 is:Vertical displacement driving motor 521 is logicalCross vertical displacement synchronous belt driving wheel 524, vertical displacement synchronizes belt tensioner pulley 523 and realizes and vertical displacement synchronous belt 522 is turnedDynamic driving, so as to which vertical displacement synchronous belt tooth plate 525 be driven to slide, vertical displacement synchronous belt tooth plate 525 can then drive vertical positionMove vertical displacement slide unit sliding block 526-b (and other subsidiary bodies thereon in straight line slide unit 526:It is loaded bar 532) up and downVertical movement.In the process, the small position to vertical displacement synchronous belt 522 then can be achieved in vertical displacement photoelectric sensor 528Shifting signal detects, and improves system control accuracy.
Sample is quantitatively handled up, and system 530 includes sample plunger pump 531, sample-adding bar 532, sample are quantitatively handled up pipe-line system533, sample plunger pump 531 includes pump head and motor, and sample plunger pump 531 is fixed on instrument internal stent, is loaded bar532 be cylinder hollow structure, and the head end of sample-adding bar 532, to facilitate insertion suction nozzle, is loaded the installation of bar 532 and fixes for pyramidal structureOn vertical displacement slide unit sliding block 526-b, sample quantitatively handles up pipe-line system 533 for pipeline configuration, and sample is quantitatively handled up pipelineSystem 533 head end connection sample-adding bar 532 end outlet, sample quantitatively handle up pipe-line system 533 end connection sample columnPlug 531 entrances of pump.Quantitatively the handle up allomeric function of system 530 of sample is:Sample plunger pump 531 is quantitatively handled up pipeline by sampleSystem 533 realizes the absorption to suction nozzle on sample-adding bar 532 or discharge effect, so as to fulfill suction nozzle on sample-adding bar 532 in test tubeThe absorption of liquid or discharge function.
Tui Guan mechanisms 540 include moving back pipe baffle ring 541, move back pipe baffle ring 541 as circular ring structure, are fixed on by stent verticalStraight 527 lower section of displacement stent, is socketed in 532 top of sample-adding bar, and the diameter for moving back pipe baffle ring 541 is more slightly larger than the diameter for being loaded bar 532,It is more slightly smaller than with sample-adding 532 matching used suction nozzle end diameter of bar, when suction nozzle use finishes, vertical displacement slide unit sliding block 526-B drives vertical displacement stent 527 to move up, and pipe baffle ring 541 is moved back when the suction nozzle connected on vertical displacement stent 527 touchesAfterwards, it is just detached from and falls on pipe baffle ring 541 from moving back, pipe function is moved back in realization.
The comprehensive function of sample integrated treatment mechanism 500 is:Horizontal displacement mechanism 510 and vertical deviation mechanism 520 are distinguishedIt realizes that level and vertical deviation to being loaded bar 532 move, moves so as to fulfill two dimensional surface, quantitatively handled up system by sample530 can be achieved, to absorption or discharge function of the suction nozzle on sample-adding bar 532 to examination liquid in pipe, to pass through the Tui Guan mechanisms 540It then can be achieved to move back pipe function to suction nozzle on sample-adding bar 532.
Waste product slot 600 is rounded cylindrical structure, and the outer diameter of waste product slot 600 is smaller than shaft open-work 213, and waste product slot 600 is installedIt is fixed on 211 center of turntable disk body.When the horizontal displacement mechanism 510 and vertical deviation mechanism in sample integrated treatment mechanism 500When suction nozzle on 520 drive sample-adding bars 532 moves to waste product 600 top of slot, the suction nozzle being detached from by Tui Guan mechanisms 540 is just fallenEnter in waste product slot 600, realize the recycling of discarded suction nozzle.
Electric-control system 700 includes lower computer control system 710, upper computer control system 720, lower computer control system 710Including controller 711, driving module 712, power module 713, communication module 714, controller 711 is the control core of a whole set of instrumentThe heart is arranged on instrument internal, the connection driving of controller 711 module 712, power module 713, communication module 714.Controller 711Main function it is as follows:
1. control driving module 712 works, and then realizes to turntable driving motor 231, traversing driving motor 314, levelThe driving effect of displacement drive motor 511, vertical displacement driving motor 521;
2. driving photoelectric sensor system 313 works, realize to vertical driving synchronous belt 312-b and traversing driving synchronous beltThe micro-displacement signal detection of 315-b displacements increases control accuracy;
3. control quantitative plunger pump 321 works, the quantitative accurate extraction to reagent is realized;
4. control light path detection module 420 works, the concentration of iodine is calculated according to the degree of absorption of light;
5. driving horizontal displacement photoelectric sensor 518 and vertical displacement photoelectric sensor 528 work, realize to horizontal displacement522 micro-displacement signal detection of synchronous belt 512 and vertical displacement synchronous belt respectively constitutes closed-loop control system and improves control essenceDegree;
Sample plunger pump 531 6. control sample is quantitatively handled up in system 530 works, and realizes to suction nozzle on sample-adding bar 532Absorption or discharge effect.
Module 712 is driven to include multiple drivers, respectively drives turntable driving motor 231, traversing driving motor 314, waterProsposition moves driving motor 511, vertical displacement driving motor 521, and power module 713 is mounted on instrument internal, primarily serves transformationThe functions such as rectification, the input terminal connection power interface 120 of power module 713, output terminal connection driving module 712 and communication module714 and provide electric energy for it.Communication module 714 is connect with communication interface 130, and communication module 714 can be by the logical of controller 711News parameter is transmitted to communication interface 130 and is analyzed for host computer computer 721, can also receive parameter and biography from communication interface 130Controller 711 is defeated by for instruction execution etc..The major function of lower computer control system 710 is:Controller 711 realizes the number of instrumentAccording to the functions such as processing and control, driving module 712 is then realized to instrument internal executing agency (turntable driving motor 231, traversing driveDynamic motor 314, horizontal displacement driving motor 511, vertical displacement driving motor 521 etc.) driving, power module 713 then realizesVoltage is converted and power supply function of supplying power, and the communication work(between instrument and external host computer computer 721 then can be achieved in communication module 714Energy.
Upper computer control system 720 include host computer computer 721, host computer computer 721 be industrial personal computer computer, upper electromechanicsBrain 721 is connect by Serial Port Line with communication interface 130, is subjected to parameter and status information from instrument and equipment etc..Host computerBe equipped in computer 721 with the matching used control software of this instrument and equipment, realize to sample carriers mechanism 200, reagent liquid feedingThe calibration effect of each executing agency, realizes the Various types of data sent to instrument in device 300 and sample integrated treatment mechanism 500It the functions such as analyzed, handled, stored and is inquired, can also receive the operational order from staff, be converted into code commandIt is transferred in lower computer control system 710 by Serial Port Line, realizes manipulation function of the staff to instrument and equipment.
The allomeric function of electric-control system 700 is:Lower computer control system 710 mainly realize the control of instrument and equipment, power supply,The functions such as communication, upper computer control system 720 then can be achieved and 710 communication function of lower computer control system, while can also handleData from lower computer control system 710, and to functions such as data analysis, processing, storage and inquiries, in addition PC controlSystem 720 can also send control instruction to realize the control and operation to instrument and equipment to lower computer control system 710.
Further, turntable synchronous belt 225, vertical driving synchronous belt 312-b, traversing driving synchronous belt 315-b, horizontal positionMove synchronous belt 512, vertical displacement synchronous belt 522 is belt composition or chain structure.Turntable transport mechanism 220, vertical driving passDynamic system 312, laterally driven transmission system 315, horizontal displacement mechanism 510 and vertical deviation mechanism 520 are belt transmission or toothWheel transmission.
Further, turntable driving motor 231, traversing driving motor 314, horizontal displacement driving motor 511, vertical displacementDriving motor 521 is one kind in stepper motor, servo motor or direct current generator, and 231 shaft end of turntable driving motor is set by compilingCode device.
Further, the quantitative plunger pump 321 in reagent liquid-adding device 300, liquid transfer gun head carrier 322 and liquid feeding pipeline systemSystem 323 is multiple.
The method of work of above-mentioned fully-automatic intelligent urine iodine analyzer, includes the following steps:
(1) communicating step:
1) staff sets working method in host computer computer 721.
2) host computer computer 721 inputs staff instruction morphing, and passes through Serial Port Line and be transferred to communication module 714In, and be finally-transmitted in controller 711.
3) controller 711 can communication control module 714 by the running parameter of itself, state and the sensing data of acquisitionHost computer computer 721 is transferred to, the parameter received and data for staff are checked, analyzed, stored by host computer computer 721And decision.
(2) test sample addition step:
1) on reaction cup slot array 211-c of the staff in 210 outermost sample cell bit array 212 of sample turntableThe test tube of placing response places specimen bottle, in the liquid-transfering gun mouth slot battle array of innermost ring in intermediate specimen cup slot array 212-bClean suction nozzle is placed on row 212-a, relevant parameter is set in host computer computer 721 and starts machine.
2) control of controller 711 driving 712 driving disc driving motor 231 of module rotates, and passes through turntable transport mechanism 220Sample turntable 210 is driven to rotate, the pending reagent sample of first row is driven to rotate to designated position.
3) control of controller 711 driving module 712 drives the horizontal displacement mechanism 510 in sample integrated treatment mechanism 500It is moved with vertical deviation mechanism 520, sample-adding bar 532 is driven to move to right over liquid-transfering gun mouth slot array 212-a.
4) control of controller 711 driving module 712 drives the vertical deviation mechanism 520 in sample integrated treatment mechanism 500It moves downward, sample-adding bar 532 is driven to continue to move downward, be loaded bar 532 and suction nozzle thereon is inserted into liquid-transfering gun mouth slot arrayInside the upper clean suction nozzles of 212-a, installation suction nozzle function is completed.
5) control of controller 711 driving module 712 drives the horizontal displacement mechanism 510 in sample integrated treatment mechanism 500It is moved with vertical deviation mechanism 520, the sample-adding bar 532 for being inserted with clean suction nozzle is driven to move to pending specimen cup slot arrayRight over 212-b.
6) control of controller 711 driving module 712 drives the vertical deviation mechanism 520 in sample integrated treatment mechanism 500It moves downward, sample-adding bar 532 is driven to move downward, the suction nozzle on sample-adding bar 532 is driven to be inserted into specimen cup slot array 212-b and is treatedSurvey sample interior, controller 711 control quantitatively fixed point liquid feeding system 320 act, draw a certain amount of liquid to be tested.
7) control of controller 711 driving module 712 drives the horizontal displacement mechanism 510 in sample integrated treatment mechanism 500It is moved with vertical deviation mechanism 520, it is anti-that the suction nozzle that driving the suction on sample-adding bar 532 has testing liquid moves to pending first rowAnswer the surface of the reaction tube of cup slot array 211-c.
8) controller 711 control quantitatively fixed point liquid feeding system 320 spue a certain amount of liquid to be tested to pending first rowIn test tube, test sample is completed out of test tube on specimen cup slot array 212-b to the examination on reaction cup slot array 211-cAddition in pipe.
(3) auxiliary reagent addition step:
1) on color developing agent sample-adding bar 322-a, oxidant sample-adding bar 322-b of the staff on liquid transfer gun head carrier 322Two pollution-free completely new suction nozzles are installed.
2) in above-mentioned sample adding procedure, controller 711 control driving 712 driving disc driving motor 231 of module afterContinuous rotation drives sample turntable 210 to rotate by turntable transport mechanism 220, drive the pending reagent sample of first row rotate toDesignated position.
3) control of controller 711 driving module 712 drives traversing driving motor 314 and then drives laterally driven transmission system315 actions drive the sample-adding bar of the color developing agent on the liquid transfer gun head carrier 322 on reagent pipetting volume transverse arm 317 322-a, oxidant to addSample bar 322-b and rifle mouth thereon are rotated around the vertical axis 316 of reagent pipetting volume to reagent adding trough 110.
4) control of controller 711 driving module 712 drives vertical driving motor 311 to rotate, and passes through vertical driving power trainSystem 312 drives color developing agent sample-adding bar 322-a, the oxidant sample-adding bar 322-b on liquid transfer gun head carrier 322 and suction nozzle thereonDecline and be inserted into auxiliary reagent pond.
5) controller 711 control quantitatively fixed point liquid feeding system 320 work so that two suctions on liquid transfer gun head carrier 322Quantitative fixed point draws a certain amount of auxiliary reagent to head respectively.
6) control of controller 711 driving module 712 drives vertical driving motor 311 to rotate, and passes through vertical driving power trainColor developing agent sample-adding bar 322-a, oxidant sample-adding bar 322-b and suction on 312 drive liquid transfer gun head carrier 322 of system have reagentSuction nozzle rises and leaves auxiliary reagent pond.
7) as needed, the control of controller 711 driving module 712, which drives traversing driving motor 314 and then drives, laterally drivesDynamic transmission system 315 acts, and drives the color developing agent sample-adding bar 322-a on the liquid transfer gun head carrier 322 on reagent pipetting volume transverse arm 317On suction nozzle right over the reaction tube that the vertical axis 316 of reagent pipetting volume rotates on reaction cup slot array 211-c to be measured.
8) controller 711 control quantitatively fixed point liquid feeding system 320 work so that the color developing agent on liquid transfer gun head carrier 322Suction nozzle on sample-adding bar 322-a quantitatively pinpoints a certain amount of auxiliary reagent that spues.
9) as needed, the control of controller 711 driving module 712, which drives traversing driving motor 314 and then drives, laterally drivesDynamic transmission system 315 acts, and drives the oxidant sample-adding bar 322-b on the liquid transfer gun head carrier 322 on reagent pipetting volume transverse arm 317On suction nozzle realize position micro-shifting around the rotation of reagent pipetting volume vertical axis 316, the suction nozzle on oxidant sample-adding bar 322-b is moved toRight over reaction tube on reaction cup slot array 211-c to be measured.
10) controller 711 control quantitatively fixed point liquid feeding system 320 work so that oxidant adds on liquid transfer gun head carrier 322Suction nozzle on sample bar 322-b quantitatively pinpoints a certain amount of auxiliary reagent that spues, and addition auxiliary examination is so far completed in sample to be tested test tubeAgent operation.
11) control of controller 711 control driving module 712 drives vertical driving motor 311 to rotate, and is passed by vertical drivingDynamic system 312 drives color developing agent sample-adding bar 322-a, oxidant sample-adding bar 322-b on liquid transfer gun head carrier 322 to set back,Complete primary sample-adding operation.
(4) test sample whipping step:
1) after completing auxiliary reagent addition operation, the control driving 712 driving disc driving motor 231 of module of controller 711Rotation drives sample turntable 210 to rotate, drives the pending reagent for being added to auxiliary reagent by turntable transport mechanism 220Sample tube is rotated to designated position.
2) control of controller 711 driving module 712 drives the horizontal displacement mechanism 510 in sample integrated treatment mechanism 500It is moved with vertical deviation mechanism 520, the sample-adding bar 532 for being inserted with suction nozzle is driven to move to the reaction in specimen cup slot array 212-bRight over cup test tube.
3) control of controller 711 driving module 712 drives the vertical deviation mechanism 520 in sample integrated treatment mechanism 500It moves downward, sample-adding bar 532 and suction nozzle thereon is driven to move downward, the suction nozzle on sample-adding bar 532 is driven to be inserted into specimen cup slotIn reaction cup test tube in array 212-b.
4) controller 711 control quantitatively fixed point liquid feeding system 320 draw a certain amount of sample liquid to be tested.
5) control of controller 711 driving module 712 drives the vertical deviation mechanism 520 in sample integrated treatment mechanism 500It moves upwards, sample-adding bar 532 and suction nozzle thereon is driven to move upwards and leave the examination of the reaction cup in specimen cup slot array 212-bPipe rim of a cup a distance.
6) controller 711 control quantitatively fixed point liquid feeding system 320 spue all liquid to be tested, so far complete once to sampleLiquid mixing in reaction cup test tube in product cup slot array 212-b.
7) 3) -6 are repeated the above steps) once, second is completed in the reaction cup test tube in specimen cup slot array 212-bLiquid mixed function.
8) as needed be repeated twice and above-mentioned steps 3 more than twice) -6), realize to liquid in test tube to be measuredUniformly mixing.
(5) pipe step is moved back:
1) after controller 711, which controls, completes test sample addition and hybrid manipulation, the control driving module of controller 711Horizontal displacement mechanism 510 and vertical deviation mechanism 520 in 712 driving sample integrated treatment mechanisms 500 move, and drive is inserted with suctionThe sample-adding bar 532 of head is moved to right over waste product slot 600.
2) control of controller 711 driving module 712 drives the vertical deviation mechanism 520 in sample integrated treatment mechanism 500It continues up, sample-adding bar 532 and suction nozzle thereon is driven to move upwards, until suction nozzle topmost touches Tui Guan mechanismsPipe baffle ring 541 is moved back in 540, suction nozzle is moved back pipe baffle ring 541 and backed off at this time, is fallen into waste product slot 600, and pipe operation is moved back in completion.
(6) urine iodine concentration step is calculated:
1) control of controller 711 driving 712 driving disc driving motor 231 of module rotates, and passes through turntable transport mechanism 220Sample turntable 210 is driven to rotate, drives the reaction cup test tube that has been added on the reaction cup slot array 211-c of test agent to lightBetween road detection module 420.
2) controller 711 controls special light emitting diode 421 to work, through colorimetric pool 411, test sample test tube, test solutionBody is reached in silicon photo diode 422.
3) controller 711 controls silicon photo diode 422 to work, and receives the light of specific wavelength and senses intensity of illumination, controlsDevice 711 processed calculates urine iodine concentration according to intensity of illumination.

Claims (7)

1. a kind of fully-automatic intelligent urinates iodine analyzer, which is characterized in that including casing, sample carriers mechanism, reagent liquid-adding device,Light path detection, sample integrated treatment mechanism, waste product slot and electric-control system, casing include top half and lower half portion, onSample integrated treatment mechanism is provided in half part, lower half portion is equipped with sample carriers mechanism, reagent liquid-adding device, light path detectionSystem, sample integrated treatment mechanism, waste product slot and electric-control system, the upper surface of the lower half portion of casing are provided with reagent additionSlot, the side of casing are equipped with power interface, communication interface, thermovent and power switch;
Sample carriers mechanism includes sample turntable, turntable transport mechanism, rotary disc driving mechanism;Sample turntable include turntable disk body,Sample cell bit array, shaft open-work, test tube support disk body, specimen cup slot position support array, turntable disk body is with certain thicknessDisc structure, be arranged on the upper surface of casing lower half portion, three circle circular holes, Circularhole diameter be uniformly distributed on turntable disk bodySlightly it is coarser than reagent pipe diameter, the circular hole often enclosed is radially consistent along turntable disk body, every group of corresponding radially aligned point of three circular holeCloth, the array of three circle circular hole compositions is sample cell bit array, and three circle circular holes are respectively from inner ring to outer ring:Liquid-transfering gun mouth slot battle arrayRow, specimen cup slot array, reaction cup slot array place liquid relief rifle mouth, specimen cup slot array, reaction on liquid-transfering gun mouth slot arrayCup slot array then places sample tube and reaction test tube respectively, and turntable disk body is provided centrally with the through-hole of major diameter, is shaftOpen-work to install turntable bearing, waste product slot is provided in the inner annular space of turntable bearing, is provided on test tube support disk bodySpecimen cup slot position supports array, and specimen cup slot position support array is corresponded with sample cell bit array position, sample cell bit arrayIt is set on test tube support disk body, totally three circles, the slot position often enclosed is radially consistent along test tube support disk body, every group of corresponding three slotThe radially aligned distribution in position, it is pyramidal structure that specimen cup slot position, which supports each slot position shape in array, and test tube support disk body is pacifiedDress is fixed on turntable disk body lower end, connect and fixes with turntable disk body, and rotated together with turntable disk body by stent;Turntable passesMechanism is sent to include turntable bearing, shaft, the driven synchronous pulley of turntable, turntable driving synchronous pulley, turntable synchronous belt, turntable bearingInner ring lower end connection shaft, the fixed turntable disk body of inner ring upper end connection and test tube support disk body, the outer shroud connection of turntable bearingIt is fixed on instrument support, shaft bottom end is provided with the driven synchronous pulley of turntable, and the driven synchronous pulley of turntable is synchronized by turntableBand is connect with turntable driving synchronous pulley, and turntable driving synchronous pulley is arranged on turntable driving motor, and electricity is driven by turntableThe driving of machine drives turntable driving synchronous pulley rotation;Rotary disc driving mechanism includes turntable driving motor, turntable driving motor branchFrame, turntable driving motor frame bottom are fixed on instrument, and turntable driving motor is mounted on turntable driving motor stent, turntableThe output revolving shaft of driving motor is fixed at turntable driving synchronous pulley axle center, and turntable driving motor is also connected with driving moduleIn corresponding motor driver;
Reagent liquid-adding device includes reagent pipetting volume mechanical arm, quantitatively pinpoints liquid feeding system, quantitatively pinpoints liquid feeding system and includes quantifyingPlunger pump, liquid transfer gun head carrier, liquid feeding pipe-line system, quantitative plunger pump, liquid transfer gun head carrier, liquid feeding pipe-line system are twoSet, liquid feeding pipe-line system are common pipe-line system, connect quantitative plunger pump and liquid transfer gun head carrier, quantitative plunger pump installation respectivelyIt is fixed on instrument internal stent, including color developing agent quantitative plunger pump and oxidant quantitative plunger pump, liquid transfer gun head carrier includesColor developing agent sample-adding bar, oxidant sample-adding bar, color developing agent are loaded bar and connect color developing agent quantitative plunger pump by liquid feeding pipe-line systemEntrance, oxidant are loaded the entrance that bar connects oxidant quantitative plunger pump by liquid feeding pipe-line system;
Light path detection includes colorimetric carrier, light path detection module, and colorimetric carrier includes colorimetric pool, hood, colorimetric pool branchColumn, colorimetric pool are two layers inside and outside annular, inside and outside colorimetric pool between two layers can holding test tubes, the corresponding sample of outermost layer on turntable disk bodyProduct slot bit array is corresponding with the annulate lamella of colorimetric pool, hood be ring sector structure, bottom hollow out, on turntable disk body mostAbove the corresponding sample cell bit array of outer layer, hood is fixed on the upper of the casing lower half portion above light path detection moduleOn end face, colorimetric pool pillar is elongated stanchions, and quantity is four, and colorimetric pool pillar upper end is fixed with colorimetric pool, and lower end installation is solidIt is scheduled on casing;Light path detection module includes special light emitting diode, silicon photo diode, and special light emitting diode is arranged on colorimetricThe outside of pond cyclic structure, below hood, special light emitting diode is also connected with controller, and silicon photo diode is mounted on spyThe opposite of light emitting diode processed, in the inside of colorimetric pool cyclic structure, silicon photo diode uses in pairs with special light emitting diode,Silicon photo diode is connected with controller;
Electric-control system includes lower computer control system, upper computer control system, and lower computer control system includes controller, driving mouldGroup, power module, communication module, controller are the control core of a whole set of instrument, are arranged on instrument internal, controller connection drivingModule, power module, communication module, driving module include multiple drivers, respectively drive turntable driving motor, traversing driving electricityMachine, horizontal displacement driving motor, vertical displacement driving motor, the input terminal connection power interface of power module, output terminal connectionDriving module and communication module, communication module are connect with communication interface;Upper computer control system includes host computer computer, host computerComputer is connect by Serial Port Line with communication interface.
Vertical driving transmission system include vertical driving synchronize belt tensioner pulley, vertical driving synchronous belt, vertical driving synchronous pulley,Vertical driving synchronous belt tooth plate, vertical axis pallet, vertical driving synchronous pulley are mounted on the output revolving shaft of vertical driving motor,Vertical driving synchronizes belt tensioner pulley and is mounted remotely from vertical driving synchronous pulley side, vertical driving synchronous belt tensioning by shaftWheel and vertical driving synchronous pulley are in approximately the same plane, and axle axis is parallel, and vertical driving synchronous pulley is sleeved on reagent and addsOn the vertical axis of sample, by bearing and the vertical axis connection of reagent pipetting volume, and the vertical axis of reagent pipetting volume can be in vertical driving synchronous pulleyIt moves up and down, is fixed on vertical driving synchronous belt on the inside of vertical driving synchronous belt tooth plate, outside in bearing at axle centerThe component that need to be driven is installed, vertical driving synchronous belt tooth plate is also connected with being fixed on vertical axis pallet, and vertical axis tray outline isSemicircle slab construction connect fixation with the lower end of the vertical axis of reagent pipetting volume at axle center by bearing, and side and vertical driving are sameStep band truss plate connection and fixation, the vertical axis of reagent pipetting volume can rotate, and move up slip with vertical axis pallet around vertical axis pallet;
Laterally driven transmission system includes traversing driving synchronous pulley, traversing driving synchronous belt, traversing driven synchronous pulley, traversingVertical connecting rod, traversing swing arm, vertical slip transverse arm, traversing driving synchronous pulley is mounted in the shaft of traversing driving motor, horizontalIt moves driving synchronous belt to be socketed between traversing driving synchronous pulley and traversing driven synchronous pulley, traversing driven synchronous pulley socketOn the vertical axis of reagent pipetting volume, traversing driven synchronous pulley drives synchronous pulley in the same plane with traversing, traversing vertical companyBar is elongated straight rod structure, and traversing vertical small end is fixed on the inside of the disk border of vertical driving synchronous pulley, and composition is inclinedHeart wheeling disk structure drives traversing vertical connecting rod to be rotated with certain radius, and then drive by the rotation of vertical driving synchronous pulleyTraversing swing arm rotation, traversing swing arm shape are oval strip slab construction, and the head end of traversing swing arm is connected to liquid feeding by shaftOn the bottom end platform of mechanical arm support, it can be rotated around the shaft at head end, the end of traversing swing arm is fixed with traversing vertical connecting rod,Vertical slip transverse arm is strip slab construction, and one end upper surface of vertical slip transverse arm connects with the lower face of the vertical axis of reagent pipetting volumeFixation is connect, and the upper surface of vertical slip transverse arm strip slab construction contacts with the lower face of vertical axis pallet and connects fixation,The other end of vertical slip transverse arm is vertically provided with open-work at center, and traversing vertical connecting rod is passed through from open-work,The vertical axis of reagent pipetting volume is circular shaft, is arranged at traversing driven synchronous pulley axle center by bearing arrangement, can be in vertical directionLower movement, the vertical axis lower end of reagent pipetting volume are fastened on vertical axis pallet;
Reagent pipetting volume transverse arm is horizontal cross plate structure, and the side of reagent pipetting volume transverse arm is fastened on the vertical axis of reagent pipetting volumeEnd, other side are fixed with liquid transfer gun head carrier, and liquid feeding mechanical arm protective cover is plektron, lower openings, and inner hollow is socketed inOn reagent pipetting volume transverse arm, liquid feeding machinery arm support be MULTILAYER COMPOSITE mechanism, be vertical driving motor, vertical driving transmission system,Photoelectric sensor system, traversing driving motor, laterally driven transmission system, the vertical axis of reagent pipetting volume installation immobilization carrier, liquid feedingMechanical arm support installation is scheduled on the inside of casing lower half portion.
3. fully-automatic intelligent as claimed in claim 2 urinates iodine analyzer, which is characterized in that the horizontal displacement mechanism includes waterProsposition moves driving motor, horizontal displacement synchronous belt, horizontal displacement synchronization belt tensioner pulley, horizontal displacement synchronous belt driving wheel, levelDisplacement synchronous band tooth plate, horizontal displacement straight line slide unit, horizontal displacement stent, horizontal displacement photoelectric sensor, horizontal displacement drivingMotor is mounted on horizontal displacement stent, and horizontal displacement driving motor is also connected with the respective drivers in driving module, horizontal positionShifting synchronous belt is interior toothed timing, is socketed in horizontal displacement and synchronizes between belt tensioner pulley and horizontal displacement synchronous belt driving wheel, waterProsposition moves synchronous belt tensioner pulley and is mounted on horizontal displacement stent by shaft, mounting plane and horizontal displacement synchronous belt driving wheelPlace plane is consistent, and horizontal displacement synchronous belt driving wheel is mounted on the output revolving shaft of horizontal displacement driving motor, horizontal displacementSynchronous belt tooth plate is the flat bed platform that can be fixed on synchronous belt, and horizontal position is fixed on the inside of horizontal displacement synchronous belt tooth plateIt moves on synchronous belt, the horizontal displacement slide unit ontology on the fixed horizontal displacement straight line slide unit of outside installation, horizontal displacement straight line slide unitIncluding horizontal displacement slide unit ontology, horizontal displacement slide unit sliding block, horizontal displacement slide unit ontology is horizontal on horizontal displacement stent, waterProsposition moves slide unit sliding block and can be moved forward and backward under the induced effect of horizontal displacement synchronous belt tooth plate along horizontal displacement slide unit ontology, waterProsposition moves on slide unit sliding block and also connect fixation with vertical displacement pedestal upper end, and horizontal displacement stent is slab construction, horizontal displacementThe lower end of stent connect fixation with casing internal, and horizontal displacement stent is fixedly connected with horizontal displacement by bolt nut structure and drivesDynamic motor, horizontal displacement synchronize belt tensioner pulley, horizontal displacement synchronous belt driving wheel, horizontal displacement straight line slide unit, horizontal displacement lightElectric transducer includes transmitting module, receiving module and Signal-regulated kinase, and horizontal displacement photoelectric sensor is mounted on by stentThe side of horizontal displacement synchronous belt, horizontal displacement photoelectric sensor and horizontal displacement driving motor, horizontal displacement synchronous belt, levelDisplacement synchronous belt tensioner pulley, horizontal displacement synchronous belt driving wheel form closed-loop control system;
Vertical deviation mechanism includes vertical displacement driving motor, vertical displacement synchronous belt, vertical displacement synchronize belt tensioner pulley, verticalDisplacement synchronous band driving wheel, vertical displacement synchronous belt tooth plate, vertical displacement straight line slide unit, vertical displacement stent, vertical displacement lightElectric transducer, backplate, vertical displacement driving motor are mounted on vertical displacement stent, and vertical displacement driving motor is also connected with drivingRespective drivers in module, vertical displacement synchronous belt are socketed in vertical displacement and synchronize belt tensioner pulley and the drive of vertical displacement synchronous beltBetween driving wheel, vertical displacement synchronizes belt tensioner pulley and is mounted on vertical displacement stent by shaft, mounting plane and vertical displacementPlane where synchronous belt driving wheel is consistent, and vertical displacement synchronous belt driving wheel is mounted on the output revolving shaft of vertical displacement driving motorOn, it is fixed on vertical displacement synchronous belt on the inside of vertical displacement synchronous belt tooth plate, outside installation fixed vertical displacement straight lineVertical displacement slide unit ontology on slide unit, vertical displacement straight line slide unit includes vertical displacement slide unit ontology, vertical displacement slide unit is slidedBlock, vertical displacement slide unit ontology are vertically arranged on vertical displacement stent, and vertical displacement slide unit sliding block is in vertical displacement synchronous beltIt is moved under the drive of tooth plate along vertical above and below vertical displacement slide unit ontology, vertical displacement pedestal upper end is fixed on horizontal displacement slide unitOn sliding block, vertical displacement stent is fixedly connected with vertical displacement driving motor, vertical displacement synchronous belt by bolt nut structureTensioning wheel, vertical displacement synchronous belt driving wheel, vertical displacement straight line slide unit, vertical displacement photoelectric sensor include transmitting module,Receiving module and Signal-regulated kinase, vertical displacement photoelectric sensor are mounted on the side of vertical displacement synchronous belt by stent,It is the synchronous belt tensioner pulley of vertical displacement photoelectric sensor and vertical displacement driving motor, vertical displacement synchronous belt, vertical displacement, verticalDisplacement synchronous band driving wheel forms closed-loop control system, and backplate is laminar right angle angle bar, on vertical displacement stent, positionIn vertical displacement driving motor, vertical displacement synchronous belt, vertical displacement synchronize belt tensioner pulley, vertical displacement synchronous belt driving wheel,The outside of vertical displacement synchronous belt tooth plate, vertical displacement straight line slide unit;
CN201810137209.0A2018-02-102018-02-10A kind of fully-automatic intelligent urine iodine analyzer and its method of workPendingCN108152285A (en)

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CN109297952A (en)*2018-11-092019-02-01南京信息工程大学 Discrimination system of rice paper quality based on laser-induced breakdown spectroscopy
CN109541244A (en)*2018-10-302019-03-29长沙塞克陆德医疗科技有限公司A kind of iodine element automatic detector and its control method
CN110275033A (en)*2019-07-152019-09-24杭州德译医疗科技有限公司 A human urine automatic detection system
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CN109541244A (en)*2018-10-302019-03-29长沙塞克陆德医疗科技有限公司A kind of iodine element automatic detector and its control method
CN109297952B (en)*2018-11-092024-02-06南京信息工程大学Rice paper quality identification system based on laser-induced breakdown spectroscopy technology
CN109297952A (en)*2018-11-092019-02-01南京信息工程大学 Discrimination system of rice paper quality based on laser-induced breakdown spectroscopy
CN110275033A (en)*2019-07-152019-09-24杭州德译医疗科技有限公司 A human urine automatic detection system
CN110665558A (en)*2019-11-112020-01-10马冬梅Automatic reagent precise adding device
CN111044742A (en)*2020-01-062020-04-21无锡集佳智能科技有限公司Intelligent sample processing and detecting device
CN112116753A (en)*2020-08-312020-12-22同济大学Self-service outpatient service machine
CN113219190A (en)*2021-05-172021-08-06青岛市三凯医学科技有限公司Full-automatic layered heating and cooling detection equipment and method
CN113219190B (en)*2021-05-172022-05-24青岛市三凯医学科技有限公司Full-automatic layered heating and cooling detection equipment and method
WO2023005049A1 (en)*2021-07-292023-02-02中国人民解放军陆军军医大学第一附属医院Automated synthesis instrument for cartilage biomimetic matrix gel
CN113447669A (en)*2021-08-132021-09-28成都斯马特科技有限公司Immunoassay appearance
CN113466159A (en)*2021-09-032021-10-01江苏海枫达生物科技有限公司Intelligent chemical analyzer capable of avoiding cross contamination
CN113466159B (en)*2021-09-032021-11-02江苏海枫达生物科技有限公司Intelligent chemical analyzer capable of avoiding cross contamination
CN113866444A (en)*2021-09-242021-12-31无锡集佳智能科技有限公司 A kind of automatic sample adding and mixing device for spectrophotometry pretreatment
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