CN107789017B - Mitral valve clip - Google Patents
Mitral valve clipDownload PDFInfo
- Publication number
- CN107789017B CN107789017BCN201610788399.3ACN201610788399ACN107789017BCN 107789017 BCN107789017 BCN 107789017BCN 201610788399 ACN201610788399 ACN 201610788399ACN 107789017 BCN107789017 BCN 107789017B
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- mitral valve
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- valve clip
- flaps
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- 230000003511endothelial effectEffects0.000claimsdescription3
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- 239000000463materialSubstances0.000claimsdescription3
- HLXZNVUGXRDIFK-UHFFFAOYSA-Nnickel titaniumChemical compound[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni]HLXZNVUGXRDIFK-UHFFFAOYSA-N0.000claimsdescription3
- 229910001000nickel titaniumInorganic materials0.000claimsdescription3
- 206010027727Mitral valve incompetenceDiseases0.000abstractdescription4
- 210000005240left ventricleAnatomy0.000description4
- 230000000694effectsEffects0.000description3
- 208000018578heart valve diseaseDiseases0.000description3
- 206010067171RegurgitationDiseases0.000description2
- 238000012986modificationMethods0.000description2
- 230000004048modificationEffects0.000description2
- 238000001356surgical procedureMethods0.000description2
- 229910001030Iron–nickel alloyInorganic materials0.000description1
- 230000032683agingEffects0.000description1
- 238000005452bendingMethods0.000description1
- 230000009286beneficial effectEffects0.000description1
- 201000010099diseaseDiseases0.000description1
- 208000037265diseases, disorders, signs and symptomsDiseases0.000description1
- 238000005516engineering processMethods0.000description1
- 208000014674injuryDiseases0.000description1
- 239000002184metalSubstances0.000description1
- 229910052751metalInorganic materials0.000description1
- 230000017074necrotic cell deathEffects0.000description1
- 230000005855radiationEffects0.000description1
- 230000008733traumaEffects0.000description1
- 238000002604ultrasonographyMethods0.000description1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
Abstract
Description
Technical Field
The present invention relates to a mitral valve clip.
Background
With the advent of aging population, the incidence of valvular heart disease has increased significantly. The traditional treatment mode for mitral regurgitation is valve repair or valve replacement, but the operation damage is large, and the related complications are more, so that many elderly patients with serious valvular disease cannot receive treatment. In recent years, surgical treatment of valvular heart disease is gradually minimally invasive, treatment of interventional valvular heart disease is rapidly developed due to the advantages of small trauma, relative safety, good curative effect and the like, indications of the treatment are continuously expanded, contraindications are relatively reduced, curative effect of interventional surgery is more certain, and some new technologies become new hotspots for interventional cardiology research.
Disclosure of Invention
The technical problem to be solved by the present invention is to overcome the drawbacks of the prior art and to provide a mitral valve clamp for treating a heart with a reduced risk of mitral regurgitation.
The invention solves the technical problems through the following technical scheme:
a mitral valve clip, comprising:
two first flaps, two second flaps and a central portion;
wherein one of both ends of each of the first sheets is connected to a central portion, one of both ends of each of the second sheets is connected to a central portion, the two first sheets are simultaneously openable and closable with respect to the central portion, and the two second sheets are simultaneously openable and closable with respect to the central portion;
when the two first sheets and the two second sheets are opened, the two first sheets are positioned at the same side of the two second sheets, and the first sheets and the second sheets form a clamp.
Preferably, the surface of the first sheet facing the second sheet is provided with barbs.
Preferably, the surfaces of the mitral valve clip are each coated with a fabric or surface treated so that endothelial tissue can climb the surface of the mitral valve clip.
Preferably, the material of the first and second flaps is nitinol.
Preferably, the mitral valve clip further comprises a cylindrical portion, the central portion comprises a first central piece and a second central piece sleeved outside the first central piece, the cylindrical portion is sleeved on the second central piece, the first central piece can slide relative to the second central piece, and the second central piece can slide relative to the cylindrical portion; the first sheet-like object and the second sheet-like object are both elastic components bent into a preset angle; one end of each of the two first sheets is connected with the first central piece, and one end of each of the two second sheets is connected with the second central piece.
Preferably, the first and second flaps are both thermoformed components.
Preferably, each of the first flaps includes a first leaf-shaped portion and a first rod-shaped portion, one end of the first rod-shaped portion is connected to the first central member, the other end of the first rod-shaped portion is connected to the first leaf-shaped portion, the first rod-shaped portion is bent to the predetermined angle, and the cross-sectional shape of the first leaf-shaped portion is an arc shape;
each second flap comprises a second leaf part and a second rod-shaped part, one end of the second rod-shaped part is connected with the second central piece, the other end of the second rod-shaped part is connected with the second leaf part, the second rod-shaped part is bent to the preset angle, and the cross section of the second leaf part is arc-shaped.
Preferably, the predetermined angle is 100-120 degrees.
Preferably, the predetermined angle is 110 degrees.
Preferably, two notches are respectively opened on two opposite side surfaces of the cylindrical part, and the notches are formed to be recessed from one end of the cylindrical part to the other end.
Preferably, the mitral valve clip further includes a control portion that is fixed to the cylindrical portion, and the control portion is connected to the first center piece and the second center piece, respectively, and controls sliding of the first center piece and the second center piece.
Preferably, the control portion includes a control tube and two control rods, the two control rods are located in the control tube, the control tube is fixedly connected to the cylindrical portion, and the two control rods are respectively connected to the first center piece and the second center piece and control sliding of the first center piece and the second center piece.
The positive progress effects of the invention are as follows: the mitral valve clamp can be passed through a catheter into the heart and clamp the normally unoccluded mitral valve by creating a clamp between the first flap and the second flap, thereby preventing mitral regurgitation.
Drawings
FIG. 1 is a front view of a mitral valve clip according to an embodiment of the present invention;
FIG. 2 is a front view of a mitral valve clip according to an embodiment of the present invention, wherein the second flap is open;
FIG. 3 is a schematic front view of a mitral valve clip according to an embodiment of the present invention, wherein the first flap and the second flap are both open;
fig. 4 is a front view of the mitral valve clip of fig. 2 with the cylindrical portion removed.
Detailed Description
The present invention is further illustrated by way of example and not by way of limitation in the scope of the described embodiments in connection with the accompanying drawings.
As shown in fig. 1-4,mitral valve clip 10 comprises: twofirst sheets 11, twosecond sheets 12, a central portion and acylindrical portion 15.
The central part comprises a firstcentral part 13 and a secondcentral part 14 sleeved outside the firstcentral part 13, acylindrical part 15 is sleeved on the secondcentral part 14, the firstcentral part 13 can slide relative to the secondcentral part 14, and the secondcentral part 14 can slide relative to thecylindrical part 15.
Twonotches 151 are opened in opposite side surfaces of thecylindrical portion 15, respectively, and thenotches 151 are formed to be recessed from one end of thecylindrical portion 15 toward the other end.
Thefirst sheet 11 and thesecond sheet 12 are each an elastic member bent at a predetermined angle; one end of each of the twofirst flaps 11 is connected to a firstcentral piece 13 and one end of each of the twosecond flaps 12 is connected to a secondcentral piece 14.
The twofirst flaps 11 can be simultaneously opened and simultaneously closed with respect to the firstcentral member 13, and the twosecond flaps 12 can be simultaneously opened and simultaneously closed with respect to the secondcentral member 14. When both first andsecond flaps first flaps 11 are in the same direction as bothsecond flaps 12 and thefirst flaps 11 form a grip with thesecond flaps 12.
The first andsecond flaps
Each of thefirst sheets 11 includes afirst leaf portion 111 and afirst rod portion 112, one end of thefirst rod portion 112 is connected to the firstcentral member 13, the other end of thefirst rod portion 112 is connected to thefirst leaf portion 111, the first rod portion is bent at a predetermined angle, and the cross-sectional shape of thefirst leaf portion 111 is arc-shaped. The predetermined angle is preferably 100-120 degrees, more preferably 110 degrees, to better conform to the upper surface of the mitral valve.
Eachsecond flap 12 includes asecond leaf 121 and asecond rod 122, one end of thesecond rod 122 is connected to the secondcentral element 14, the other end of thesecond rod 122 is connected to thesecond leaf 121, the second rod is bent at a predetermined angle, and the cross-sectional shape of thesecond leaf 121 is arc-shaped. As shown in fig. 4, the predetermined angle R is preferably 100 degrees and 120 degrees, and more preferably 110 degrees, to better conform to the inferior surface of the mitral valve.
Themitral valve clip 10 further includes a control portion that is fixed to thecylindrical portion 15, is connected to the first andsecond centerpieces second centerpieces cylindrical portion 15, and two control rods connected to the first andsecond centerpieces second centerpieces
The surface of thefirst sheet 11 facing thesecond sheet 12 is provided with barbs. The barb structure is beneficial to better clamping the mitral valve leaflets and can not cause necrosis of the cells of the leaflets.
The surfaces of themitral valve clip 10 are each coated with a fabric or surface treated so that the endothelial tissue can climb the surface of themitral valve clip 10.
The material of the first andsecond flaps first sheet 11 and thesecond sheet 12 are accurately bent to a predetermined angle by using the shape memory thereof.
The manner in which themitral valve clip 10 is used is briefly described below.
The operator first makes a puncture from the left chest incision and the apex of the heart of the patient, then inserts the catheter into the left ventricle along the opening, and then sends themitral valve clip 10 from the catheter into the left ventricle via the delivery device, from where it enters the mitral valve via ultrasound and radiation guidance. Themitral valve clip 10 is in a collapsed state in the catheter, as shown in fig. 1, with both thefirst flap 11 and thesecond flap 12 collapsed in thecylindrical portion 15. After themitral valve clip 10 enters the left ventricle, the sliding of the first andsecond centerpieces second core member 14 is slid upward until the bent portion of thesecond sheet 12 is disengaged from thecylindrical portion 15, and thesecond sheet 12 is opened, as shown in fig. 2. The upper surface of thesecond flap 12 is then caused to conform to the lower surface of the mitral valve. Then, the control unit controls thefirst centering element 13 to slide upward until the bending portion of thefirst sheet 11 is separated from thesecond centering element 14, thefirst sheet 11 is opened, and the openedfirst sheet 11 forms a clamp with thesecond sheet 12 therebelow, as shown in fig. 3, so as to clamp the two leaflets of the mitral valve, and then detects whether the mitral valve has regurgitation or has a significantly reduced regurgitation phenomenon to determine whether themitral valve clamp 10 is clamped in the correct position. If it is judged that themitral valve clip 10 has been clipped in the correct position, the first andsecond center pieces second sheets cylindrical portion 15 and the leaflets held by both are also firmly clipped in themitral valve clip 10 through thenotches 151 of thecylindrical portion 15.
After this, themitral valve clip 10 is disengaged from the delivery device, which is then withdrawn from the left ventricle and the patient's apex puncture site and left chest incision are sutured.
The invention has shorter path through interventional operation, is easier to operate in the operation, can accurately find the proper clamping position of the mitral valve, has shorter operation time and higher operation success rate.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
While specific embodiments of the invention have been described above, it will be appreciated by those skilled in the art that this is by way of example only, and that the scope of the invention is defined by the appended claims. Various changes and modifications to these embodiments may be made by those skilled in the art without departing from the spirit and scope of the invention, and these changes and modifications are within the scope of the invention.
Claims (9)
1. A mitral valve clip, comprising:
two first flaps, two second flaps and a central portion;
wherein one of both ends of each of the first sheets is connected to a central portion, one of both ends of each of the second sheets is connected to a central portion, the two first sheets are simultaneously openable and closable with respect to the central portion, and the two second sheets are simultaneously openable and closable with respect to the central portion;
when the two first sheets and the two second sheets are opened, the two first sheets are positioned at the same side of the two second sheets, and the first sheets and the second sheets form a clamp;
the mitral valve clamp further comprises a cylindrical part, the central part comprises a first central piece and a second central piece sleeved outside the first central piece, the cylindrical part is sleeved on the second central piece, the first central piece can slide relative to the second central piece, and the second central piece can slide relative to the cylindrical part; the first sheet-like object and the second sheet-like object are both elastic components bent into a preset angle; one end of each of the two first sheets is connected with the first central piece, and one end of each of the two second sheets is connected with the second central piece;
the first and second flaps are both thermoformed components;
two notches are respectively formed in two opposite side faces of the cylindrical portion, and the notches are formed to be recessed from one end of the cylindrical portion to the other end of the cylindrical portion.
2. The mitral valve clip of claim 1, wherein a surface of the first flap facing the second flap is provided with barbs.
3. The mitral valve clip of claim 1, wherein surfaces of the mitral valve clip are each coated with a fabric or surface treated so that endothelial tissue can climb the surface of the mitral valve clip.
4. The mitral valve clip of claim 1, wherein the material of the first and second flaps is nitinol.
5. The mitral valve clip of claim 1, wherein each of the first flaps comprises a first leaflet and a first stem, one end of the first stem being connected to the first hub and the other end of the first stem being connected to the first leaflet, the first stem being bent at the predetermined angle, the first leaflet having a cross-sectional shape that is an arc;
each second flap comprises a second leaf part and a second rod-shaped part, one end of the second rod-shaped part is connected with the second central piece, the other end of the second rod-shaped part is connected with the second leaf part, the second rod-shaped part is bent to the preset angle, and the cross section of the second leaf part is arc-shaped.
6. The mitral valve clip of claim 1, wherein the predetermined angle is 100 degrees and 120 degrees.
7. The mitral valve clip of claim 6, wherein the predetermined angle is 110 degrees.
8. The mitral valve clip of claim 1, further comprising a control portion secured to the cylindrical portion, the control portion being connected to and controlling sliding of the first and second centerpieces, respectively.
9. The mitral valve clamp of claim 8, wherein the control portion includes a control tube and two control rods, the two control rods being located in the control tube, the control tube being secured to the cylindrical portion, the two control rods being connected to and controlling sliding of the first and second centerpieces, respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610788399.3ACN107789017B (en) | 2016-08-31 | 2016-08-31 | Mitral valve clip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610788399.3ACN107789017B (en) | 2016-08-31 | 2016-08-31 | Mitral valve clip |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107789017A CN107789017A (en) | 2018-03-13 |
| CN107789017Btrue CN107789017B (en) | 2020-12-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610788399.3AActiveCN107789017B (en) | 2016-08-31 | 2016-08-31 | Mitral valve clip |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107789017B (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US10517719B2 (en) | 2008-12-22 | 2019-12-31 | Valtech Cardio, Ltd. | Implantation of repair devices in the heart |
| US8449599B2 (en) | 2009-12-04 | 2013-05-28 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
| US9439763B2 (en) | 2013-02-04 | 2016-09-13 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
| US9622863B2 (en) | 2013-11-22 | 2017-04-18 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
| WO2016090308A1 (en) | 2014-12-04 | 2016-06-09 | Edwards Lifesciences Corporation | Percutaneous clip for repairing a heart valve |
| EP3294219B1 (en) | 2015-05-14 | 2020-05-13 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
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| US10973638B2 (en) | 2016-07-07 | 2021-04-13 | Edwards Lifesciences Corporation | Device and method for treating vascular insufficiency |
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| US11065117B2 (en) | 2017-09-08 | 2021-07-20 | Edwards Lifesciences Corporation | Axisymmetric adjustable device for treating mitral regurgitation |
| US11040174B2 (en) | 2017-09-19 | 2021-06-22 | Edwards Lifesciences Corporation | Multi-direction steerable handles for steering catheters |
| US10123873B1 (en) | 2018-01-09 | 2018-11-13 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
| FI3964175T3 (en) | 2018-01-09 | 2024-12-03 | Edwards Lifesciences Corp | Native valve repair devices |
| US10231837B1 (en) | 2018-01-09 | 2019-03-19 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
| US10111751B1 (en) | 2018-01-09 | 2018-10-30 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
| US10945844B2 (en) | 2018-10-10 | 2021-03-16 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
| CN113226223A (en) | 2018-11-20 | 2021-08-06 | 爱德华兹生命科学公司 | Deployment tools and methods for delivering devices to native heart valves |
| CA3118988A1 (en) | 2018-11-21 | 2020-05-28 | Edwards Lifesciences Corporation | Heart valve sealing devices, delivery devices therefor, and retrieval devices |
| CR20210312A (en) | 2018-11-29 | 2021-09-14 | Edwards Lifesciences Corp | Catheterization method and apparatus |
| ES2969252T3 (en) | 2019-02-14 | 2024-05-17 | Edwards Lifesciences Corp | Heart valve sealing devices and delivery devices therefor |
| WO2021082821A1 (en)* | 2019-10-31 | 2021-05-06 | 杭州德晋医疗科技有限公司 | Valve clamp capable of detecting valve gripped state, and valve clamping system |
| EP3915493B1 (en)* | 2020-03-30 | 2022-08-10 | Lepu Medical Technology (Beijing) Co., Ltd. | Heart valve clip |
| US12133799B2 (en)* | 2020-06-24 | 2024-11-05 | Medtronic Vascular, Inc. | Ligating devices and methods for heart valve repair |
| CN112168427A (en)* | 2020-11-02 | 2021-01-05 | 上海竑宇医疗科技有限公司 | Heart apex implantation cusp clamping device and heart apex implantation cusp clamping method |
| USD1071198S1 (en) | 2023-06-28 | 2025-04-15 | Edwards Lifesciences Corporation | Cradle |
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| US8945177B2 (en)* | 2011-09-13 | 2015-02-03 | Abbott Cardiovascular Systems Inc. | Gripper pusher mechanism for tissue apposition systems |
| CN105877803B (en)* | 2016-05-27 | 2020-04-07 | 苏州法兰克曼医疗器械有限公司 | Hemostatic clamp |
| CN106175986B (en)* | 2016-07-26 | 2017-12-01 | 复旦大学附属中山医院 | A kind of valve clamping machine |
- 2016
- 2016-08-31CNCN201610788399.3Apatent/CN107789017B/enactiveActive
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| CN107789017A (en) | 2018-03-13 |
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