技术领域technical field
本发明涉及一种基于鱼类心电指标的水质评价方法、系统。The invention relates to a water quality evaluation method and system based on fish ECG indicators.
背景技术Background technique
对环境中的水质进行评价是水环境治理中的重要基础性工作。通过对水质监测得到的数据进行合理科学的评价，才能制定科学有效的规划整治，采取有效合理的措施。因此水质评价的合理性是相当重要的。The evaluation of water quality in the environment is an important basic work in water environment governance. Only by making a reasonable and scientific evaluation of the data obtained from water quality monitoring can we formulate scientific and effective planning and rectification and take effective and reasonable measures. Therefore, the rationality of water quality evaluation is very important.
目前，用来评价水质的方法有很多，在以往的水污染治理当中，人们一般采取的方法主要是理化监测值的监测方法，虽然能够合理有效的进行监测水质，但是在监测的过程之中，却会受到很多各方面因素的影响，这给水质监测工作带来了一定的困难。At present, there are many methods used to evaluate water quality. In the past water pollution control, people generally adopt the monitoring method of physical and chemical monitoring value. Although the water quality can be monitored reasonably and effectively, in the process of monitoring, However, it will be affected by many factors, which brings certain difficulties to the water quality monitoring work.
为了能够准确监测水环境的水质状况，越来越多的研究者利用生物来评价和监测水质环境，大部分生物水质监测方法具有复杂、不易执行的特点，因此，有必要研究具有实用价值的生物水质监测方法。In order to accurately monitor the water quality of the water environment, more and more researchers use organisms to evaluate and monitor the water quality environment. Most biological water quality monitoring methods are complex and difficult to implement. Therefore, it is necessary to study biological Water quality monitoring methods.
发明内容Contents of the invention
针对现有技术中存在的不足，本发明提供了一种基于鱼类心电指标的水质评价方法，本方法利用鱼类生物在不同浓度镉威胁源下的心电信号反应，反向评价出水源的污染物浓度，方法具有普适性，可以广泛应用于水质镉污染物的评价。Aiming at the deficiencies in the prior art, the present invention provides a water quality evaluation method based on fish ECG indicators. This method uses the ECG signal responses of fish organisms under different concentrations of cadmium threats to reversely evaluate the water source. The method is universal and can be widely used in the evaluation of cadmium pollutants in water quality.
本发明的技术方案为：Technical scheme of the present invention is:
基于鱼类心电指标的水质评价方法，包括：Water quality evaluation method based on fish ECG indicators, including:
在多个实验水源中分别放置不同浓度的镉威胁源；Place different concentrations of cadmium threat sources in multiple experimental water sources;
提取鱼类生物在所述不同浓度镉威胁源下的心电信号；Extracting the electrocardiographic signals of fish organisms under the threat sources of different concentrations of cadmium;
提取不同浓度下心电信号的波峰振幅以及各个波峰之间的时间间隔，所述波峰峰值包括P波振幅、Q波振幅、R波振幅、S波振幅、T波振幅，所述各个波峰之间的时间间隔包括PR波间期时长、QRS间期时长、ST波间期时长以及QT波间期时长；Extract the peak amplitudes of ECG signals at different concentrations and the time interval between each peak. The peaks include P wave amplitude, Q wave amplitude, R wave amplitude, S wave amplitude, and T wave amplitude. The time interval includes the duration of the PR wave interval, the duration of the QRS interval, the duration of the ST wave interval, and the duration of the QT wave interval;
根据不同浓度镉威胁源下的QRS间期时长，制作浓度时长关系对应表；According to the QRS interval duration under different concentrations of cadmium threat sources, make a concentration-time-length relationship correspondence table;
在待测水源中放入未知浓度的镉威胁源，将与上述鱼类生物同种的鱼类暴露在所述待测水源中，提取此时鱼类心电信号的QRS间期时长，通过查表获得待测水源的污染物浓度。A cadmium threat source of unknown concentration was put into the water source to be tested, and fish of the same species as the above-mentioned fish organisms were exposed to the water source to be tested, and the QRS interval duration of the fish ECG signal was extracted at this time. The table obtains the concentration of pollutants in the water source to be tested.
进一步的，可以对所述心电信号进行小波去噪处理，小波基可以选用sym4，层数根据信号的去噪效果进行调整。Further, wavelet denoising processing can be performed on the ECG signal, the wavelet base can be sym4, and the number of layers can be adjusted according to the denoising effect of the signal.
进一步的，采用基于Matlab的组织映射原理分析所述心电信号，对所述心电信号的波峰振幅以及各个波峰之间的时间间隔进行聚类分析，得到不同浓度镉威胁源下的各个峰值变化情况和各个时间间隔的变化情况。Further, the electrocardiographic signal is analyzed by using the principle of tissue mapping based on Matlab, and the peak amplitude of the electrocardiographic signal and the time interval between each peak are clustered and analyzed to obtain the peak changes under different concentrations of cadmium threat sources conditions and changes over time.
进一步的，将不同浓度镉威胁源下的各个峰值变化情况、各个时间间隔的变化情况与镉威胁源浓度的变化情况做对比，挑选与所述镉威胁源浓度变化趋势一致的QRS间期时长。Further, the change of each peak value and the change of each time interval under different concentrations of cadmium threat sources are compared with the changes of the concentration of cadmium threat sources, and the QRS interval length is selected that is consistent with the change trend of the concentration of cadmium threat sources.
具体采集过程中，每隔固定时间间隔提取鱼类生物在所述不同浓度镉威胁源下的心电信号，对同一浓度镉威胁源下的不同时刻提取的P波振幅、Q波振幅、R波振幅、S波振幅、T波振幅、PR波间期时长、QRS间期时长、ST波间期时长以及QT波间期时长进行平均，得到不同浓度镉威胁源下的心电信号平均值。In the specific collection process, the electrocardiographic signals of fish organisms under the threat sources of different concentrations of cadmium are extracted at regular intervals, and the P wave amplitude, Q wave amplitude, and R wave amplitude extracted at different times under the same concentration of cadmium threat source are extracted. Amplitude, S wave amplitude, T wave amplitude, PR wave interval duration, QRS interval duration, ST wave interval duration, and QT wave interval duration were averaged to obtain the average value of ECG signals under different concentrations of cadmium threat sources.
本发明又提出了一种基于鱼类心电指标的水质评价系统，包括：The present invention proposes a kind of water quality evaluation system based on electrocardiogram index of fish again, comprises:
试验平台，用于放置多个实验水源和待测水源，每个实验水源中放置鱼类生物，每个实验水源中的镉威胁源浓度为已知且不同，待测水源中的镉威胁源浓度未知；The test platform is used to place multiple experimental water sources and water sources to be tested. Fish organisms are placed in each experimental water source. The concentration of cadmium threat sources in each experimental water source is known and different. The concentration of cadmium threat sources in the test water sources is unknown;
采集装置，用于提取鱼类生物在实验水源中的心电信号和在待测水源中的心电信号；The acquisition device is used to extract the electrocardiographic signals of fish organisms in the experimental water source and the electrocardiographic signals in the water source to be tested;
计算终端，用于分析所述心电信号中的波峰振幅以及各个波峰之间的时间间隔，对比不同浓度镉威胁源下的波峰振幅变化、波峰之间的时间间隔变化与镉威胁源浓度变化的一致性，提取与所述镉威胁源浓度变化趋势相同的参数，制作所述参数与镉威胁源浓度的关系对应表；The calculation terminal is used to analyze the peak amplitude and the time interval between each peak in the electrocardiographic signal, and compare the changes of the peak amplitude and the time interval between the peaks and the concentration change of the cadmium threat source under different concentrations of cadmium threat sources. Consistency, extracting parameters with the same variation trend as the concentration of the cadmium threat source, making a corresponding table of the relationship between the parameters and the concentration of the cadmium threat source;
利用鱼类生物在待测水源中的心电信号，通过查表获得待测水源的水质；Using the ECG signal of fish organisms in the water source to be tested, the water quality of the water source to be tested is obtained by looking up the table;
在待测水源中放入未知浓度的镉威胁源，将与上述鱼类生物同种的鱼类暴露在所述待测水源中，提取此时鱼类心电信号的QRS间期时长，通过查表获得待测水源的污染物浓度。A cadmium threat source of unknown concentration was put into the water source to be tested, and fish of the same species as the above-mentioned fish organisms were exposed to the water source to be tested, and the QRS interval duration of the fish ECG signal was extracted at this time. The table obtains the concentration of pollutants in the water source to be tested.
其中，所述计算终端包括处理器，用于实现各指令；以及存储设备，用于存储多条指令，所述指令由处理器加载并执行以下处理：Wherein, the computing terminal includes a processor for implementing each instruction; and a storage device for storing a plurality of instructions, the instructions are loaded by the processor and perform the following processing:
分析P波振幅、Q波振幅、R波振幅、S波振幅、T波振幅、PR波间期时长、QRS间期时长、ST波间期时长以及QT波间期时长；采用基于Matlab的组织映射原理对所述各个波的振幅和波峰之间的时间间隔进行聚类分析，对比不同浓度镉威胁源下的各个波振幅变化、波峰之间的时间间隔变化与镉威胁源浓度变化的一致性，提取与所述镉威胁源浓度变化趋势相同的参数。Analysis of P wave amplitude, Q wave amplitude, R wave amplitude, S wave amplitude, T wave amplitude, PR interval duration, QRS interval duration, ST interval duration, and QT interval duration; using Matlab-based tissue mapping The principle is to carry out cluster analysis on the amplitude of each wave and the time interval between the peaks, and compare the consistency of the amplitude change of each wave, the time interval between the peaks and the concentration change of the cadmium threat source under different concentrations of cadmium threat sources, Extract the same parameters as the change trend of the cadmium threat source concentration.
进一步的，选取不同浓度镉威胁源下的QRS间期时长作为与镉威胁源浓度变化趋势相同的参数，制作浓度时长关系对应表。Further, the QRS interval duration under different concentrations of cadmium threat sources was selected as a parameter with the same trend as the concentration of cadmium threat sources, and the concentration-time-length relationship correspondence table was made.
进一步的，本系统还包括有显示装置，与所述计算终端相连，用于显示波峰振幅以及各个波峰之间的时间间隔，以及不同浓度镉威胁源下的波峰振幅变化情况、波峰之间的时间间隔变化情况。Further, the system also includes a display device connected to the computing terminal for displaying the peak amplitude and the time interval between each peak, as well as the change of the peak amplitude and the time between the peaks under different concentrations of cadmium threat sources interval changes.
本系统所述试验平台为敞口的壳体，壳体内部放置有柔性吸附材料。The test platform described in this system is an open shell, and flexible adsorption materials are placed inside the shell.
本发明的有益效果：Beneficial effects of the present invention:
本发明可以研究出在不同的环境胁迫下，斑马鱼的心电会出现不同的变化。经过实验发现，QRS间期和CdCl2胁迫有明显的相关性。通过研究观察和分析QRS间期是监测水质的好方法。The present invention can study that under different environmental stresses, the electrocardiogram of the zebrafish will undergo different changes. After experiments, it was found that there was a clear correlation between QRS interval and CdCl2 stress. Observing and analyzing the QRS interval through research is a good way to monitor water quality.
通过大量的实验发现，QRS间期是心电图参数中最显著的特征之一，QRS间期可以为心率的计算提供了重要的信息。因此，此检测方法可以利用心电图QRS间期来评价水质。Through a large number of experiments, it is found that the QRS interval is one of the most significant characteristics of the ECG parameters, and the QRS interval can provide important information for the calculation of the heart rate. Therefore, this detection method can use the QRS interval of the electrocardiogram to evaluate the water quality.
附图说明Description of drawings
图1是本方法用于采集心电信号的仪器及装置结构示意图；Fig. 1 is that this method is used for collecting the instrument and device structural representation of electrocardiographic signal;
图2是本方法一实施例采集到的斑马鱼的原始的心电图；Fig. 2 is the original electrocardiogram of the zebrafish collected by an embodiment of the method;
图3是本方法一实施例的原始心电图进行滤波去除干扰处理后的心电图；Fig. 3 is the electrocardiogram after the original electrocardiogram of an embodiment of the method is filtered to remove interference;
图4是本方法一实施例：氯化镉胁迫(环境压力)下斑马鱼心电特征的SOM图；Fig. 4 is an embodiment of the present method: the SOM figure of zebrafish ECG characteristics under cadmium chloride stress (environmental pressure);
图5是本方法一实施例：QRS间期与氯化镉胁迫(环境压力)的关系图。Fig. 5 is an embodiment of the method: a relation diagram between QRS interval and cadmium chloride stress (environmental pressure).
图1中，①是导线；②是铁架台；③是银制电极；④是海绵块中心位置的固定鱼体的凹槽；⑤是装有海绵的盒式容器；⑥是鱼体；⑦是多道生理信息采集系统仪器。In Fig. 1, ① is the wire; ② is the iron stand; ③ is the silver electrode; ④ is the groove for fixing the fish body in the center of the sponge block; ⑤ is the box container with the sponge; ⑥ is the fish body; ⑦ is Multi-channel physiological information collection system instrument.
具体实施方式：Detailed ways:
下面结合附图与实施例对本发明作进一步说明：Below in conjunction with accompanying drawing and embodiment the present invention will be further described:
应该指出，以下详细说明都是例示性的，旨在对本申请提供进一步的说明。除非另有指明，本文使用的所有技术和科学术语具有与本申请所属技术领域的普通技术人员通常理解的相同含义。It should be pointed out that the following detailed description is exemplary and intended to provide further explanation to the present application. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.
需要注意的是，这里所使用的术语仅是为了描述具体实施方式，而非意图限制根据本申请的示例性实施方式。如在这里所使用的，除非上下文另外明确指出，否则单数形式也意图包括复数形式，此外，还应当理解的是，当在本说明书中使用术语“包含”和/或“包括”时，其指明存在特征、步骤、操作、器件、组件和/或它们的组合。It should be noted that the terminology used here is only for describing specific implementations, and is not intended to limit the exemplary implementations according to the present application. As used herein, unless the context clearly dictates otherwise, the singular is intended to include the plural, and it should also be understood that when the terms "comprising" and/or "comprising" are used in this specification, they mean There are features, steps, operations, means, components and/or combinations thereof.
本发明的一种典型实施例是一种基于鱼类心电指标的水质评价方法与系统，方法包括：A typical embodiment of the present invention is a water quality evaluation method and system based on fish ECG indicators, the method includes:
在多个实验水源中分别放置不同浓度的镉威胁源；Place different concentrations of cadmium threat sources in multiple experimental water sources;
提取鱼类生物在所述不同浓度镉威胁源下的心电信号；Extracting the electrocardiographic signals of fish organisms under the threat sources of different concentrations of cadmium;
提取不同浓度下心电信号的波峰振幅以及各个波峰之间的时间间隔，所述波峰峰值包括P波振幅、Q波振幅、R波振幅、S波振幅、T波振幅，所述各个波峰之间的时间间隔包括PR波间期时长、QRS间期时长、ST波间期时长以及QT波间期时长；Extract the peak amplitudes of ECG signals at different concentrations and the time interval between each peak. The peaks include P wave amplitude, Q wave amplitude, R wave amplitude, S wave amplitude, and T wave amplitude. The time interval includes the duration of the PR wave interval, the duration of the QRS interval, the duration of the ST wave interval, and the duration of the QT wave interval;
根据不同浓度镉威胁源下的QRS间期时长，制作浓度时长关系对应表；According to the QRS interval duration under different concentrations of cadmium threat sources, make a concentration-time-length relationship correspondence table;
在待测水源中放入未知浓度的镉威胁源，将与上述鱼类生物同种的鱼类暴露在所述待测水源中，提取此时鱼类心电信号的QRS间期时长，通过查表获得待测水源的污染物浓度。A cadmium threat source of unknown concentration was put into the water source to be tested, and fish of the same species as the above-mentioned fish organisms were exposed to the water source to be tested, and the QRS interval duration of the fish ECG signal was extracted at this time. The table obtains the concentration of pollutants in the water source to be tested.
系统包括：The system includes:
试验平台，用于放置多个实验水源和待测水源，每个实验水源中放置鱼类生物，每个实验水源中的镉威胁源浓度为已知且不同，待测水源中的镉威胁源浓度未知；The test platform is used to place multiple experimental water sources and water sources to be tested. Fish organisms are placed in each experimental water source. The concentration of cadmium threat sources in each experimental water source is known and different. The concentration of cadmium threat sources in the test water sources is unknown;
采集装置，用于提取鱼类生物在实验水源中的心电信号和在待测水源中的心电信号；The acquisition device is used to extract the electrocardiographic signals of fish organisms in the experimental water source and the electrocardiographic signals in the water source to be tested;
计算终端，用于分析所述心电信号中的波峰振幅以及各个波峰之间的时间间隔，对比不同浓度镉威胁源下的波峰振幅变化、波峰之间的时间间隔变化与镉威胁源浓度变化的一致性，提取与所述镉威胁源浓度变化趋势相同的参数，制作所述参数与镉威胁源浓度的关系对应表；The calculation terminal is used to analyze the peak amplitude and the time interval between each peak in the electrocardiographic signal, and compare the changes of the peak amplitude and the time interval between the peaks and the concentration change of the cadmium threat source under different concentrations of cadmium threat sources. Consistency, extracting parameters with the same variation trend as the concentration of the cadmium threat source, making a corresponding table of the relationship between the parameters and the concentration of the cadmium threat source;
利用鱼类生物在待测水源中的心电信号，通过查表获得待测水源的水质；Using the ECG signal of fish organisms in the water source to be tested, the water quality of the water source to be tested is obtained by looking up the table;
在待测水源中放入未知浓度的镉威胁源，将与上述鱼类生物同种的鱼类暴露在所述待测水源中，提取此时鱼类心电信号的QRS间期时长，通过查表获得待测水源的污染物浓度。A cadmium threat source of unknown concentration was put into the water source to be tested, and fish of the same species as the above-mentioned fish organisms were exposed to the water source to be tested, and the QRS interval duration of the fish ECG signal was extracted at this time. The table obtains the concentration of pollutants in the water source to be tested.
为了实现在未知浓度水源中评价污染物，我们首先进行实验，制作与镉威胁源变化趋势相一致的参数关系对应表。In order to realize the evaluation of pollutants in water sources with unknown concentrations, we first conduct experiments and make a parameter relationship correspondence table that is consistent with the changing trend of cadmium threat sources.
具体的，通过一种在线采集心电信号的方法与系统对鱼的心电信号进行采集(见图1)，该采集装置主要包括RM-6240C多道生理信息采集系统仪器、鱼体固定装置、导线、电极、主机等；该采集方法能够较为稳定的采集心电信号(见图2)，也能够尽最大努力减少外界的干扰对信号采集带来的影响；然后通过对采集到的心电图进行滤波和去除干扰处理，得到更为清晰的心电图(见图3)；然后通过计算终端的系统软件进行心电图分析，将分析后的数据进行处理，再将处理后的数据用Matlab进行分析，并用组织映射SOM图进行表征出来(见图4)，根据数据差异判断心电的变化。Specifically, the electrocardiographic signals of fish are collected through a method and system for collecting electrocardiographic signals online (see Figure 1), the collection device mainly includes RM-6240C multi-channel physiological information collection system instrument, fish body fixing device Wires, electrodes, hosts, etc.; this acquisition method can collect ECG signals more stably (see Figure 2), and can also try its best to reduce the impact of external interference on signal acquisition; and then filter the collected ECG and remove interference processing to obtain a clearer ECG (see Figure 3); then analyze the ECG through the system software of the computing terminal, process the analyzed data, and then analyze the processed data with Matlab and use tissue mapping The SOM diagram is used to characterize (see Figure 4), and the ECG changes can be judged according to the data difference.
首先将斑马鱼暴露在氯化镉溶液中，氯化镉对于斑马鱼的48h半致死浓度为42.6mg/l，记为1毒性单位(1TU)，将斑马鱼暴露在不同浓度的氯化镉中作处理，暴露浓度分别为4.26mg/l，21.3mg/l和42.6mg/l(0.1TU，0.5TU和1TU)。每个暴露浓度中都分别在特定的时间点(0h，2h，4h，8h，16h，32h，48h)对暴露中的斑马鱼进行采集测取心电信号，每个时间点采集10条斑马鱼的心电信号，每条斑马鱼心电信号采集时间为3分钟。Firstly, zebrafish were exposed to cadmium chloride solution. The semi-lethal concentration of cadmium chloride for zebrafish was 42.6 mg/l in 48 hours, recorded as 1 toxicity unit (1TU), and zebrafish were exposed to different concentrations of cadmium chloride. For treatment, exposure concentrations were 4.26mg/l, 21.3mg/l and 42.6mg/l (0.1TU, 0.5TU and 1TU). In each exposure concentration, the exposed zebrafish were collected at specific time points (0h, 2h, 4h, 8h, 16h, 32h, 48h) to measure ECG signals, and 10 zebrafish were collected at each time point The ECG signal of each zebrafish was collected for 3 minutes.
我们的试验平台为敞口的壳体，壳体内部放置有柔性吸附材料，在本实施例中，柔性吸附材料选择高密度海绵，根据鱼体大小在海绵中心位置设计一个鱼体模型的凹槽，使鱼体可以恰好固定在模型里。注入标准水质的水，直至水平面高于海绵块上表面；将斑马鱼鱼体放置于海绵块中心位置的鱼型凹槽里。Our test platform is an open shell, and a flexible absorbent material is placed inside the shell. In this example, the flexible absorbent material is a high-density sponge, and a fish body model groove is designed in the center of the sponge according to the size of the fish body. , so that the fish body can be exactly fixed in the model. Inject standard water quality water until the water level is higher than the upper surface of the sponge block; place the zebrafish body in the fish-shaped groove at the center of the sponge block.
将银制采集电极埋入斑马鱼的围心腔内，而参考电极埋入斑马鱼的泄殖孔附近，埋入鱼体的电极长度相等，约为2—4mm，采集到的心电信号通过多道生理信息采集系统输出到计算终端；计算终端可分析鱼体心电信息,通过多通道生理信号处理器将采集到的心电信号输出到文本文档；主计算终端自接受到的鱼体心电信号中提取P波振幅、Q波振幅、R波振幅、S波振幅、T波振幅和P波-R波间期时长、QRS间期时长、S波-T波间期时长以及Q波-T波间期时长9个指标。通过Matlab进行数据处理和分析，并用组织映射SOM图进行表征出来，根据数据差异判断心电的变化。The silver acquisition electrode was embedded in the pericardial cavity of the zebrafish, and the reference electrode was embedded near the cloaca of the zebrafish. The length of the electrodes embedded in the fish body was equal, about 2-4mm, and the collected ECG signals were passed through The multi-channel physiological information collection system outputs to the computing terminal; the computing terminal can analyze the electrocardiographic information of the fish body, and output the collected electrocardiographic signal to a text file through the multi-channel physiological signal processor; Extract P wave amplitude, Q wave amplitude, R wave amplitude, S wave amplitude, T wave amplitude, P wave-R wave interval duration, QRS interval duration, S wave-T wave interval duration, and Q wave- There are 9 indicators for the length of the T wave interval. The data is processed and analyzed by Matlab, and the tissue map SOM diagram is used to represent it, and the changes of ECG are judged according to the data difference.
本系统还包括有显示装置，与计算终端相连，可以显示波峰振幅以及各个波峰之间的时间间隔，以及不同浓度镉威胁源下的波峰振幅变化情况、波峰之间的时间间隔变化情况。The system also includes a display device, which is connected to the computing terminal, and can display the peak amplitude and the time interval between each peak, as well as the change of the peak amplitude and the time interval between the peaks under different concentrations of cadmium threats.
在心电各参数中，通过组织映射(SOM)表明，P波、R波和T波变化趋势相似，R波和T波变化趋势是相似的；最重要的是，在包括氯化镉胁迫和所有心电参数的分类数据模式中，QRS间期与环境压力极其相似。这表明QRS间期的时长与环境压力E有关。(见图4)Among the various parameters of ECG, it was shown by tissue mapping (SOM) that the change trends of P wave, R wave and T wave were similar, and the change trend of R wave and T wave was similar; Among the categorical data patterns of ECG parameters, the QRS interval was very similar to environmental stress. This indicates that the length of the QRS interval is related to the environmental stress E. (See Figure 4)
基于线性回归的QRS间期与环境压力的相关分析表明，相关系数r＝0.729和相关显著性p＜0.01存在极显著关系(见图5)。在这种情况下，可以得出结论，QRS间期可以用作镉胁迫评估中的一个指标。The correlation analysis between QRS interval and environmental pressure based on linear regression showed that there was a very significant relationship between the correlation coefficient r=0.729 and the correlation significance p<0.01 (see Figure 5). In this case, it can be concluded that the QRS interval can be used as an indicator in the assessment of cadmium stress.
本发明研究得到了在不同的环境胁迫下，斑马鱼的心电会出现不同的变化。经过实验发现，QRS间期和CdCl2胁迫有明显的相关性。通过研究观察和分析QRS间期是监测水质的好方法。According to the research of the present invention, under different environmental stresses, different changes will appear in the electrocardiogram of zebrafish. After experiments, it was found that there was a clear correlation between QRS interval and CdCl2 stress. Observing and analyzing the QRS interval through research is a good way to monitor water quality.
事实上，QRS间期可能是心电图参数中最显著的特征之一，QRS间期可以为心率的计算提供了重要的信息。因此，此检测方法可以利用心电图QRS间期来评价水质。In fact, the QRS interval may be one of the most salient features among ECG parameters, and the QRS interval can provide important information for the calculation of heart rate. Therefore, this detection method can use the QRS interval of the electrocardiogram to evaluate the water quality.
以上所述仅为本申请的优选实施例而已，并不用于限制本申请，对于本领域的技术人员来说，本申请可以有各种更改和变化。凡在本申请的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本申请的保护范围之内。The above descriptions are only preferred embodiments of the present application, and are not intended to limit the present application. For those skilled in the art, there may be various modifications and changes in the present application. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of this application shall be included within the protection scope of this application.
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| CN201710743232.XACN107643377B (en) | 2017-08-25 | 2017-08-25 | Water quality evaluation method and system based on fish electrocardio indexes |
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| CN201710743232.XACN107643377B (en) | 2017-08-25 | 2017-08-25 | Water quality evaluation method and system based on fish electrocardio indexes |
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| CN201710743232.XAActiveCN107643377B (en) | 2017-08-25 | 2017-08-25 | Water quality evaluation method and system based on fish electrocardio indexes |
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