技术领域technical field
本发明涉及医疗用品的结构设计和应用技术领域，特别提供一种用于完全替代人体颈椎椎间盘的多孔终板式人工颈椎间盘假体。The invention relates to the technical field of structural design and application of medical supplies, and in particular provides a porous endplate type artificial cervical intervertebral disc prosthesis for completely replacing human cervical intervertebral discs.
背景技术Background technique
颈椎前路间盘切除植骨融合内固定术(ACDF)多年来一度成为治疗颈椎间盘退变的“金标准”。然而尽管该项手术能有效解除病变节段症状，但融合术后会导致病变节段生理活动度丧失，相邻节段运动及负荷增加，将在一定程度上加速邻近节段退变(参见参考文献1.Carrier CS,Bono CM,Lebl DR.Evidence-based analysis of adjacent segmentdegeneration and disease after ACDF:a systematic review.The spinejournal.2013；13:1370-8.)。其它ACDF的并发症还包括骨不愈合、内固定物移位等。为解决以上问题，人工颈椎间盘假体应运而生。人工颈椎间盘置换手术(ACDR)既保留了原有椎间高度，又有效维持了手术节段的生理活动度，减少了对邻近节段生物力学的影响，从而与ACDF相比可减缓手术邻近节段椎间盘的退变速度，具有替代ACDF的潜力。Anterior cervical discectomy, fusion and internal fixation (ACDF) has been the "gold standard" for the treatment of cervical disc degeneration for many years. However, although this operation can effectively relieve the symptoms of the diseased segment, the fusion will lead to the loss of physiological activity of the diseased segment, and the increase of motion and load of the adjacent segment, which will accelerate the degeneration of the adjacent segment to a certain extent (see reference Literature 1. Carrier CS, Bono CM, Lebl DR. Evidence-based analysis of adjacent segment degeneration and disease after ACDF: a systematic review. The spinejournal.2013; 13:1370-8.). Other complications of ACDF include bone nonunion and displacement of internal fixation. In order to solve the above problems, artificial cervical disc prosthesis came into being. Artificial cervical disc replacement (ACDR) not only retains the original intervertebral height, but also effectively maintains the physiological activity of the surgical segment, and reduces the impact on the biomechanics of adjacent segments, thus slowing down the operation of adjacent segments compared with ACDF. The degeneration rate of segmental intervertebral disc has the potential to replace ACDF.
尽管ACDR在治疗颈椎间盘退变上比ACDF具有更多的优势，但近年来也发现了ACDR相关并发症，比如椎体骨折、人工间盘假体移位、关节面磨损、终板沉陷等，其中终板沉陷发生率据报道可达10％(参见参考文献2.Thaler M,Hartmann S,Gstottner M,etal.Footprint mismatch in total cervical disc arthroplasty.Eur Spine J.2013；22:759–65)。为了避免人工颈椎间盘假体沉陷的发生率，术中充分的椎体终板准备是十分必要的。而目前市场绝大多数人工间盘假体终板表面为平面结构，术中需要切除椎体结构以适应假体终板形态，这就更多的破坏了颈椎椎体结构，增加了并发症发生率。人工颈椎间盘植入人体后，多采用机械方法，使之紧密附着于上下椎体，防止近期移位。螺钉固定易保证假体早期固定的稳定性，但会限制假体进入椎体间的深度，难以实现准确的中线对齐。龙骨固定稳定性好，不易脱出，但植入时需进行额外的椎体骨切除，在某些病例中还会在邻近节段假体植入和植入物翻修术中引起椎体骨折。此外，人工间盘假体长期置入后的移位是ACDR的另一并发症，基于此，人工颈椎间盘表面喷涂特殊涂层的出现有利于假体的长期稳定性。常见喷涂材料有磷酸钙、羟基磷灰石。虽然涂层具有良好生物相容性，但随着涂层的体内吸收，骨-假体界面松动问题随之而来，人工间盘假体的长期稳定性仍得不到很好的维持。Although ACDR has more advantages than ACDF in the treatment of cervical disc degeneration, ACDR-related complications have also been found in recent years, such as vertebral fractures, artificial disc prosthesis displacement, articular surface wear, endplate subsidence, etc. Among them, the incidence of endplate subsidence is reported to be as high as 10% (see reference 2. Thaler M, Hartmann S, Gstottner M, et al. Footprint mismatch in total cervical disc arthritis. Eur Spine J. 2013; 22:759–65). In order to avoid the incidence of artificial cervical disc prosthesis subsidence, adequate preparation of the vertebral endplate during the operation is very necessary. At present, the surface of the endplate of most artificial intervertebral disc prosthesis in the market is a planar structure, and the vertebral structure needs to be removed during the operation to adapt to the shape of the endplate of the prosthesis, which will destroy the structure of the cervical vertebral body more and increase the occurrence of complications. Rate. After the artificial cervical intervertebral disc is implanted in the human body, mechanical methods are often used to make it tightly attached to the upper and lower vertebral bodies to prevent recent displacement. Screw fixation can easily ensure the stability of the early fixation of the prosthesis, but it will limit the depth of the prosthesis into the intervertebral body, making it difficult to achieve accurate midline alignment. Keel fixation has good stability and is not easy to prolapse, but additional vertebral bone resection is required for implantation, and in some cases, vertebral fractures may be caused during adjacent segmental prosthetic implantation and implant revision. In addition, the displacement of artificial intervertebral disc prosthesis after long-term implantation is another complication of ACDR. Based on this, the appearance of special coating on the surface of artificial cervical intervertebral disc is beneficial to the long-term stability of the prosthesis. Common spray materials include calcium phosphate and hydroxyapatite. Although the coating has good biocompatibility, with the in vivo absorption of the coating, the loosening of the bone-prosthesis interface follows, and the long-term stability of the artificial disc prosthesis is still not well maintained.
鉴于目前该技术领域的这种状况，人工颈椎间盘假体作为极具发展前景的植入器械，还存在诸多不足，人们迫切希望获得一种结构合理的新型人工椎间盘假体，以便于更好的适用于颈椎的解剖和生物力学性能要求，用以完全替代颈椎椎间盘，治疗颈椎椎间盘疾病。In view of the current situation in this technical field, the artificial cervical intervertebral disc prosthesis, as a very promising implantation device, still has many deficiencies. Applicable to the anatomical and biomechanical performance requirements of the cervical spine, it is used to completely replace the cervical intervertebral disc and treat cervical intervertebral disc diseases.
发明内容Contents of the invention
本发明的目的在于提供一种多孔终板式人工颈椎间盘假体，用于治疗颈椎间盘疾病而进行人工椎间盘假体置换术，可有效的解决上述问题。The purpose of the present invention is to provide a porous endplate type artificial cervical intervertebral disc prosthesis, which is used for artificial intervertebral disc prosthesis replacement in the treatment of cervical intervertebral disc diseases, which can effectively solve the above problems.
本发明的技术方案是：一种多孔终板式人工颈椎间盘假体，包括：上终板1和下终板2；The technical solution of the present invention is: a porous endplate type artificial cervical intervertebral disc prosthesis, comprising: an upper endplate 1 and a lower endplate 2;
所述上终板1的上表面设有具有多孔结构的球面穹顶Ⅰ1a，所述上终板1的下表面设有半球形凸起1b，所述上终板1的上表面设有穿透具有多孔结构的球面穹顶Ⅰ1a的锥形凸起Ⅰ1c，所述上终板1的侧边缘设有向上延伸的夹持凸台Ⅰ1d；The upper surface of the upper end plate 1 is provided with a spherical dome I1a having a porous structure, the lower surface of the upper end plate 1 is provided with a hemispherical protrusion 1b, and the upper surface of the upper end plate 1 is provided with a penetrating The conical protrusion I1c of the spherical dome I1a of the porous structure, the side edge of the upper end plate 1 is provided with an upwardly extending clamping boss I1d;
所述下终板2的下表面设有具有多孔结构的球面穹顶Ⅱ2a，所述下终板2的上表面设有椭球形凹槽2b，所述半球形凸起1b与椭球形凹槽2b匹配构成球槽关节，所述下终板2的下表面设有穿透具有多孔结构的球面穹顶Ⅱ2a的锥形凸起Ⅱ2c，所述下终板2的侧边缘设有向下延伸的夹持凸台Ⅱ2d。The lower surface of the lower endplate 2 is provided with a spherical dome II2a having a porous structure, and the upper surface of the lower endplate 2 is provided with an ellipsoidal groove 2b, and the hemispherical protrusion 1b is matched with the ellipsoidal groove 2b A ball-socket joint is formed, the lower surface of the lower endplate 2 is provided with a conical protrusion II2c penetrating the spherical dome II2a with a porous structure, and the side edge of the lower endplate 2 is provided with a clamping protrusion extending downward. Taiwan II 2d.
优选的，所述锥形凸起Ⅰ1c和锥形凸起Ⅱ2c的数量均为3个。Preferably, there are three conical protrusions I1c and three conical protrusions II2c.
优选的，所述锥形凸起Ⅰ1c和锥形凸起Ⅱ2c均为三棱锥。Preferably, both the conical protrusions I1c and the conical protrusions II2c are triangular pyramids.
优选的，所述夹持凸台Ⅰ1d和夹持凸台Ⅱ2d的数量均为2个。Preferably, there are two clamping bosses I1d and two clamping bosses II2d.
本发明具有以下有益的效果：The present invention has the following beneficial effects:
1、本发明通过多孔球面穹顶结构设计，更好匹配椎体解剖形态，降低假体沉陷发生率。1. The present invention better matches the anatomical shape of the vertebral body and reduces the incidence of prosthesis subsidence through the design of the porous spherical dome structure.
2、本发明中终板表面多孔结构利于骨-假体假面骨长入，增加假体远期稳定性。2. The porous structure on the surface of the end plate in the present invention is beneficial to the bone-prosthesis prosthetic bone ingrowth, and increases the long-term stability of the prosthesis.
3、本发明中终板表面锥形凸起可使假体固定，防止假体移位。3. In the present invention, the conical protrusion on the surface of the end plate can fix the prosthesis and prevent the prosthesis from shifting.
4、本发明中球槽关节能够合理地保持所在节段的活动范围和承载功能，从而达到理想的人工椎间盘假体置换效果。4. The ball-and-socket joint in the present invention can reasonably maintain the range of motion and bearing function of the segment where it is located, so as to achieve an ideal artificial intervertebral disc prosthesis replacement effect.
5、本发明在术中可通过专用夹具夹持各终板，从而保证各终板置于合适的固定位置。5. In the present invention, each endplate can be clamped by a special clamp during the operation, so as to ensure that each endplate is placed in a suitable fixed position.
附图说明Description of drawings
图1本发明的结构示意图；Fig. 1 structural representation of the present invention;
图2本发明中上终板的局部结构示意图；Fig. 2 is a schematic diagram of the local structure of the upper endplate in the present invention;
图3本发明中下终板的局部结构示意图；Fig. 3 is a schematic diagram of the partial structure of the middle and lower endplate of the present invention;
图中：1、上终板；1a、具有多孔结构的球面穹顶Ⅰ；1b、半球形凸起；1c、锥形凸起Ⅰ；1d、夹持凸台Ⅰ；2、下终板；2a、具有多孔结构的球面穹顶Ⅱ；2b、椭球形凹槽；2c、锥形凸起Ⅱ；2d、夹持凸台Ⅱ。In the figure: 1, upper endplate; 1a, spherical dome with porous structure Ⅰ; 1b, hemispherical protrusion; 1c, conical protrusion Ⅰ; 1d, clamping boss Ⅰ; 2, lower endplate; 2a, Spherical dome II with porous structure; 2b, ellipsoidal groove; 2c, conical protrusion II; 2d, clamping boss II.
具体实施方式detailed description
下面结合附图和实施例对本发明进行详细描述。The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.
如图1-3所示，一种多孔终板式人工颈椎间盘假体，包括：上终板1和下终板2；As shown in Figure 1-3, a porous endplate type artificial cervical intervertebral disc prosthesis includes: an upper endplate 1 and a lower endplate 2;
上终板1的上表面设有具有多孔结构的球面穹顶Ⅰ1a，上终板1的下表面设有半球形凸起1b，上终板1的上表面设有穿透具有多孔结构的球面穹顶Ⅰ1a的锥形凸起Ⅰ1c，上终板1的侧边缘设有向上延伸的夹持凸台Ⅰ1d。The upper surface of the upper endplate 1 is provided with a spherical dome I1a with a porous structure, the lower surface of the upper endplate 1 is provided with a hemispherical protrusion 1b, and the upper surface of the upper endplate 1 is provided with a penetrating spherical dome I1a with a porous structure The tapered protrusion I1c is provided, and the side edge of the upper endplate 1 is provided with an upwardly extending clamping boss I1d.
下终板2的下表面设有具有多孔结构的球面穹顶Ⅱ2a，下终板2的上表面设有椭球形凹槽2b，半球形凸起1b与椭球形凹槽2b匹配构成球槽关节，下终板2的下表面设有穿透具有多孔结构的球面穹顶Ⅱ2a的锥形凸起Ⅱ2c，下终板2的侧边缘设有向下延伸的夹持凸台Ⅱ2d。The lower surface of the lower endplate 2 is provided with a spherical dome II 2a with a porous structure, the upper surface of the lower endplate 2 is provided with an ellipsoidal groove 2b, and the hemispherical protrusion 1b matches the ellipsoidal groove 2b to form a ball-slot joint. The lower surface of the endplate 2 is provided with a conical projection II2c penetrating through the spherical dome II2a with a porous structure, and the side edge of the lower endplate 2 is provided with a clamping boss II2d extending downward.
本发明中具有多孔结构的球面穹顶Ⅰ1a和具有多孔结构的球面穹顶Ⅱ2a能分别与相邻椎体的终板的解剖曲面相契合(与所置换椎体相应一侧接触)，并通过锥形凸起Ⅰ1c和锥形凸起Ⅱ2c进行固定。锥形凸起Ⅰ1c和锥形凸起Ⅱ2c的数量均为3个，形状为三棱锥，使之固定稳定。夹持凸台Ⅰ1d和夹持凸台Ⅱ2d的数量均为2个，夹持凸台Ⅰ1d和夹持凸台Ⅱ2d上分别设有与专用夹具配合的孔；术中，可通过专用夹具夹持本发明中的夹持凸台Ⅰ1d和夹持凸台Ⅱ2d，并将上下终板安装于合适位置，在提高手术效率的同时，保证了假体的安装位置，提高了手术效果。In the present invention, the spherical dome I1a with a porous structure and the spherical dome II2a with a porous structure can respectively fit the anatomical curved surface of the end plate of the adjacent vertebral body (contact with the corresponding side of the replaced vertebral body), and pass through the conical convex Lift I1c and tapered protrusion II2c for fixation. The number of the conical protrusions I1c and the conical protrusions II2c are three, and the shape is a triangular pyramid, so that they are fixed and stable. The number of the clamping boss I1d and the clamping boss II2d are two, and the clamping boss I1d and the clamping boss II2d are respectively provided with holes for matching with special fixtures; The clamping boss I1d and the clamping boss II2d in the invention install the upper and lower endplates in proper positions, which not only improves the operation efficiency, but also ensures the installation position of the prosthesis and improves the operation effect.
本发明在术中能够保留上下椎体的解剖曲面，减少椎体原有结构破坏，且多孔终板结构具有促进骨长入潜能，使人工颈椎间盘假体具有长期稳定能力；球槽关节具有旋转、屈伸、侧弯等三维多个自由度活动，满足人体内正常椎间盘的运动功能，本发明在此领域内具有良好的应用前景。The present invention can retain the anatomical curved surface of the upper and lower vertebral bodies during the operation, reduce the damage to the original structure of the vertebral body, and the porous endplate structure has the potential to promote bone ingrowth, so that the artificial cervical intervertebral disc prosthesis has long-term stability; the ball-socket joint has the ability to rotate , flexion and extension, lateral bending and other three-dimensional multi-degree-of-freedom activities can meet the movement functions of normal intervertebral discs in the human body. The present invention has a good application prospect in this field.
上述实施例只为说明本发明的技术构思及特点，其目的在于让熟悉此项技术的人士能够了解本发明的内容并据以实施，并不能以此限制本发明的保护范围。凡根据本发明精神实质所作的等效变化或修饰，都应涵盖在本发明的保护范围之内。The above-mentioned embodiments are only to illustrate the technical concept and characteristics of the present invention, and the purpose is to enable those skilled in the art to understand the content of the present invention and implement it accordingly, and not to limit the protection scope of the present invention. All equivalent changes or modifications made according to the spirit of the present invention shall fall within the protection scope of the present invention.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710711122.5ACN107374790A (en) | 2017-08-18 | 2017-08-18 | A kind of porous soleplate formula cervical artificial disc prosthese |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710711122.5ACN107374790A (en) | 2017-08-18 | 2017-08-18 | A kind of porous soleplate formula cervical artificial disc prosthese |
| Publication Number | Publication Date |
|---|---|
| CN107374790Atrue CN107374790A (en) | 2017-11-24 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710711122.5APendingCN107374790A (en) | 2017-08-18 | 2017-08-18 | A kind of porous soleplate formula cervical artificial disc prosthese |
| Country | Link |
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| CN (1) | CN107374790A (en) |
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| CN108095863A (en)* | 2018-01-20 | 2018-06-01 | 西安市红会医院 | A kind of 3D printing cervical artificial disc prosthese |
| CN108814776A (en)* | 2018-05-07 | 2018-11-16 | 福州大学 | Have both the artificial disc after arthroplasty of elasticity and locomitivity |
| CN112089510A (en)* | 2020-10-12 | 2020-12-18 | 四川大学华西医院 | Cervical vertebra intervertebral height maintaining device with shock-absorbing implant-bone interface load effect |
| WO2021114577A1 (en)* | 2019-12-10 | 2021-06-17 | 佛山市逸合生物科技有限公司 | Movable intervertebral disc prosthesis |
| CN113693794A (en)* | 2021-08-31 | 2021-11-26 | 郝定均 | Bionic anatomical artificial cervical intervertebral disc prosthesis and holder |
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| CN104434347A (en)* | 2014-11-13 | 2015-03-25 | 四川大学华西医院 | cervical intervertebral disc prosthesis |
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| CN201977964U (en)* | 2011-02-24 | 2011-09-21 | 四川大学华西医院 | Artificial intervertebral disc |
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| CN204839838U (en)* | 2015-06-23 | 2015-12-09 | 深圳兰度生物材料有限公司 | Artifical neck intervertebral disc false body |
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| CN108814776A (en)* | 2018-05-07 | 2018-11-16 | 福州大学 | Have both the artificial disc after arthroplasty of elasticity and locomitivity |
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