技术领域technical field
本发明涉及一种电刺激器系统，具体涉及一种带有充电功能的，用于提升器官收缩力的电刺激器系统。The invention relates to an electrical stimulator system, in particular to an electrical stimulator system with a charging function for improving organ contractility.
背景技术Background technique
慢性心力衰竭是心血管疾病的“最终归宿”，是一种高死亡率的恶性疾病，40％的患者在12个月内死亡，65％的患者在60个月内死亡。不仅如此，慢性心力衰竭的患者在所有慢性病患者中生活质量最差。收缩性慢性心力衰竭患者中，30％属于QRS波宽群体，对这部分患者，可以植入CRT(心脏再同步装置，Cardiac Resynchronization Therapy,CRT)。其余70％的患者，目前并无疗效显著的药物与治理器械。Chronic heart failure is the "final destination" of cardiovascular disease, a malignant disease with high mortality rate, 40% of patients die within 12 months, and 65% of patients die within 60 months. Not only that, but patients with chronic heart failure have the worst quality of life of all chronic diseases. Among the patients with systolic chronic heart failure, 30% belong to the wide QRS group. For these patients, a CRT (Cardiac Resynchronization Therapy, CRT) can be implanted. For the remaining 70% of patients, there is currently no effective drug or management device.
2型糖尿病是一种终身性疾病。一旦患病，需终生医疗。据《中国2型糖尿病防治指南2013》，我国糖尿病患者人口超过1亿，已成为世界上糖尿病患病人数最多的国家。同时，中国的肥胖症人口数量在过去15年里呈指数激增。据南华早报引自The Lancet的数据，截止2013年底，中国的肥胖人口为6200万人。在世界范围内，2型糖尿病患者中有超过60％同时属于肥胖人群。Type 2 diabetes is a lifelong disease. Once sick, need life-long medical treatment. According to the "Guidelines for the Prevention and Treatment of Type 2 Diabetes in China 2013", the population of diabetic patients in my country exceeds 100 million, making it the country with the largest number of diabetic patients in the world. Meanwhile, China's obesity population has exploded exponentially over the past 15 years. According to data from The Lancet quoted by the South China Morning Post, by the end of 2013, China had 62 million obese people. Worldwide, more than 60% of patients with type 2 diabetes are also obese.
现有针对慢性心力衰竭的CRT设备，不适用于QRS波窄的人群。而目前所有针对肥胖的电刺激疗法，都不足以产生高能的电刺激。已有研究证明，在心肌不应期释放高能电刺激，可以增强心脏收缩力，从而达到改善心衰的目的；另有研究证明，在胃部肌肉不应期释放高能电刺激，可以增强胃部收缩力，从而影响胃迷走神经，进而作用大脑中枢，以达到条件人体血糖分泌的功能。The existing CRT equipment for chronic heart failure is not suitable for people with narrow QRS waves. All current electrical stimulation therapies for obesity are insufficient to generate high-energy electrical stimulation. Studies have shown that the release of high-energy electrical stimulation during the refractory period of the myocardium can enhance the contractility of the heart, thereby achieving the purpose of improving heart failure; another study has proved that the release of high-energy electrical stimulation during the refractory period of the gastric muscle can strengthen the gastric muscle. Contraction force, thereby affecting the gastric vagus nerve, and then acting on the brain center to achieve the function of regulating the secretion of blood sugar in the human body.
因此，急需一种能够调控器官收缩力的高能、可充电电刺激器系统，用于治疗慢性心力衰竭、肥胖症伴2型糖尿病等疾病。Therefore, there is an urgent need for a high-energy, rechargeable electrical stimulator system capable of regulating organ contractility for the treatment of chronic heart failure, obesity with type 2 diabetes and other diseases.
发明内容Contents of the invention
本发明目的在于提供一种带有充电功能的电刺激器系统。The purpose of the present invention is to provide an electric stimulator system with charging function.
实现本发明目的的技术方案为：一种带有充电功能的电刺激器系统，包括体内系统和体外系统；The technical solution for realizing the purpose of the present invention is: an electrical stimulator system with a charging function, including an in vivo system and an in vitro system;
体内系统包括：Internal systems include:
刺激单元，用于产生电刺激的电流源或刺激电压源；A stimulation unit, a current source or a stimulation voltage source for generating electrical stimulation;
至少一对刺激电极，用于将电刺激信号施加到目标器官；at least one pair of stimulating electrodes for applying electrical stimulation signals to the target organ;
感知单元，用于对传感器采集的信息进行自适应放大；The perception unit is used to adaptively amplify the information collected by the sensor;
至少一对感知电极，用于采集器官表面的电活动；At least one pair of sensing electrodes for collecting electrical activity on the surface of the organ;
传感器，包括固定在刺激器壳体上，用于感知人体动作的加速度计传感器以及固定在感知电极导线上，用于感知器官表面肌肉运动或器官内部血流的压力传感器；Sensors, including accelerometer sensors fixed on the stimulator shell for sensing human body movements, and pressure sensors fixed on sensing electrode wires for sensing muscle movement on the surface of organs or blood flow inside organs;
体内充电单元，用于为体内系统供电；an in-body charging unit for powering the in-body system;
体内通讯单元，用于与体外系统进行通讯；an in vivo communication unit for communicating with an in vitro system;
信号存储与处理单元，用于存储电极采集到的人体生理数据，并根据不同的应用产生不同的刺激；The signal storage and processing unit is used to store the human physiological data collected by the electrodes and generate different stimuli according to different applications;
控制与电压转换单元，用于将电池电压转换为系统工作所需电压，并控制整个体内系统运转；The control and voltage conversion unit is used to convert the battery voltage into the voltage required by the system and control the operation of the entire internal system;
体外系统包括：In vitro systems include:
充电器，用于对体内充电单元进行充电，并获得体内充电相关信息，将这些信息与处理器通讯；The charger is used to charge the charging unit in the body, obtain information related to charging in the body, and communicate the information with the processor;
处理器，用于可调参数的输入，并通过无线通讯写入体内的信号存储与处理单元；同时，读取体内系统存储的信息。The processor is used for the input of adjustable parameters, and writes into the signal storage and processing unit in the body through wireless communication; at the same time, reads the information stored in the system in the body.
与现有技术相比，本发明的显著优点为：Compared with prior art, remarkable advantage of the present invention is:
本发明是一种全植入式的，能够应用于治疗慢性心力衰竭、治疗肥胖症、2型糖尿病等疾病的电刺激系统；The present invention is a fully implantable electrical stimulation system that can be applied to the treatment of chronic heart failure, obesity, type 2 diabetes and other diseases;
通过高能电刺激调节心肌收缩力，治疗慢性心力衰竭(QRS波窄)；本发明通过在心肌绝对不应期进行非兴奋性电刺激，来增强心室收缩的强度和心脏的泵送能力；病人植入该设备后，心脏射血能力以及心脏摄氧峰量会增加，住院率及死亡率会大幅下降。该设备外观类似于心脏起搏器，植入位置在人体锁骨下部；医生可以通过微创手术植入，体外配有充电设备，约一周充电一次。Regulate myocardial contractility through high-energy electrical stimulation to treat chronic heart failure (narrow QRS wave); the present invention enhances the intensity of ventricular contraction and the pumping capacity of the heart by performing non-excitatory electrical stimulation during the absolute refractory period of the myocardium; After entering the device, the heart's ejection capacity and peak oxygen uptake of the heart will increase, and the hospitalization rate and mortality rate will be greatly reduced. The appearance of the device is similar to that of a cardiac pacemaker, and it is implanted in the lower part of the human clavicle; doctors can implant it through minimally invasive surgery, and it is equipped with a charging device outside the body, which can be charged about once a week.
通过恒定低能电刺激产生饱腹感及高能电刺激调节胃肌肉收缩力，以治疗肥胖症为主，并治疗2型糖尿病；本发明通过在胃部肌肉绝对不应期进行非兴奋性电刺激来增强胃收缩的强度，同时，对胃部肌肉或胃迷走神经进行长期低能量刺激；外观类似于心脏起搏器，植入位置在人体腹部。医生可以通过腹腔镜手术植入，体外配有充电设备，约一周充电一次。Generating satiety through constant low-energy electrical stimulation and regulating gastric muscle contractility through high-energy electrical stimulation, mainly to treat obesity and type 2 diabetes; Enhance the strength of gastric contraction, and at the same time, provide long-term low-energy stimulation to gastric muscles or gastric vagus nerve; the appearance is similar to a cardiac pacemaker, and the implantation position is in the human abdomen. Doctors can implant it through laparoscopic surgery, equipped with charging equipment outside the body, and charge it about once a week.
附图说明Description of drawings
图1是本发明的带有充电功能的电刺激器系统原理图。Fig. 1 is a schematic diagram of the electric stimulator system with charging function of the present invention.
图2是本发明的应用框图。Fig. 2 is an application block diagram of the present invention.
图3是单相脉冲示意图。Figure 3 is a schematic diagram of a single-phase pulse.
图4是幅度、脉宽可调的刺激脉冲示意图。Fig. 4 is a schematic diagram of stimulation pulses with adjustable amplitude and pulse width.
图5是脉冲串示意图。Fig. 5 is a schematic diagram of a pulse train.
图6是双相脉冲示意图。Figure 6 is a schematic diagram of a biphasic pulse.
具体实施方式detailed description
结合图1、图2，一种带有充电功能的电刺激器系统，包括体内系统和体外系统；Combining Figure 1 and Figure 2, an electric stimulator system with charging function, including an in vivo system and an in vitro system;
体内系统包括：Internal systems include:
刺激单元，用于产生电刺激的电流源或刺激电压源；A stimulation unit, a current source or a stimulation voltage source for generating electrical stimulation;
至少一对刺激电极，用于将电刺激信号施加到目标器官；at least one pair of stimulating electrodes for applying electrical stimulation signals to the target organ;
感知单元，用于对传感器采集的信息进行自适应放大；The perception unit is used to adaptively amplify the information collected by the sensor;
至少一对感知电极，用于采集器官表面的电活动；At least one pair of sensing electrodes for collecting electrical activity on the surface of the organ;
传感器，包括固定在刺激器壳体上，用于感知人体动作的加速度计传感器以及固定在感知电极导线上，用于感知器官表面肌肉运动或器官内部血流的压力传感器；Sensors, including accelerometer sensors fixed on the stimulator shell for sensing human body movements, and pressure sensors fixed on sensing electrode wires for sensing muscle movement on the surface of organs or blood flow inside organs;
体内充电单元，用于为体内系统供电；an in-body charging unit for powering the in-body system;
体内通讯单元，用于与体外系统进行通讯；an in vivo communication unit for communicating with an in vitro system;
信号存储与处理单元，用于存储电极采集到的人体生理数据，并根据不同的应用产生不同的刺激；The signal storage and processing unit is used to store the human physiological data collected by the electrodes and generate different stimuli according to different applications;
控制与电压转换单元，用于将电池电压转换为系统工作所需电压，并控制整个体内系统运转；The control and voltage conversion unit is used to convert the battery voltage into the voltage required by the system and control the operation of the entire internal system;
体外系统包括：In vitro systems include:
充电器，用于对体内充电单元进行充电，并获得体内充电相关信息，将这些信息与处理器通讯；The charger is used to charge the charging unit in the body, obtain information related to charging in the body, and communicate the information with the processor;
处理器，用于可调参数的输入，并通过无线通讯写入体内的信号存储与处理单元；同时，读取体内系统存储的信息。The processor is used for the input of adjustable parameters, and writes into the signal storage and processing unit in the body through wireless communication; at the same time, reads the information stored in the system in the body.
进一步的，所述感知单元具有100-1200倍的自适应可调放大范围。Further, the sensing unit has an adaptive adjustable magnification range of 100-1200 times.
进一步的，所述系统被配置以对心脏施加电压源，传感器检测人体动作以及心脏内血流压力。Further, the system is configured to apply a voltage source to the heart, and the sensor detects human motion and blood flow pressure in the heart.
进一步的，所述系统被配置以对胃施加电流源，传感器检测胃部肌肉运动，判断是否在进食。Further, the system is configured to apply a current source to the stomach, and the sensor detects the movement of the stomach muscles to determine whether it is eating.
进一步的，所述体内充电单元还包括温度控制模块，用于监测体内充电单元温度和充电速度。充电速度至少为75mA/h，且植入体周围组织升温不超过2摄氏度。体内充电单元的容量在100-400mAh。Further, the charging unit in the body also includes a temperature control module for monitoring the temperature and charging speed of the charging unit in the body. The charging speed is at least 75mA/h, and the temperature of the surrounding tissue of the implant does not exceed 2 degrees Celsius. The capacity of the charging unit in the body is 100-400mAh.
进一步的，所述处理器包括信号处理与显示单元、控制与输入单元、体外通讯单元和存储与上传单元；Further, the processor includes a signal processing and display unit, a control and input unit, an in vitro communication unit, and a storage and upload unit;
信号处理与显示单元用于对体内存储的信息进行感知及刺激信息处理并显示；The signal processing and display unit is used to process and display the information stored in the body for perception and stimulation information;
控制与输入单元用于可调参数的输入；The control and input unit is used for the input of adjustable parameters;
体外通讯单元用于与体内通讯单元通讯；The external communication unit is used for communicating with the internal communication unit;
存储与上传单元用于存储收集的信息并上传至服务器。The storage and upload unit is used to store the collected information and upload it to the server.
进一步的，所述体内通讯单元的通讯方式为近场通讯、射频通讯或蓝牙通讯。Further, the communication mode of the in-body communication unit is near field communication, radio frequency communication or bluetooth communication.
进一步的，所述充电器包括充电单元和通讯单元，分别用于充电和获取体内充电单元信息。Further, the charger includes a charging unit and a communication unit, which are respectively used for charging and obtaining information about the charging unit in the body.
本发明刺激单元产生的刺激波形范围如下：The scope of the stimulation waveform produced by the stimulation unit of the present invention is as follows:
单相脉冲：单相是指刺激脉冲只有一个相位，如图3所示。Monophasic pulse: Monophasic means that the stimulation pulse has only one phase, as shown in Figure 3.
以下单相脉冲的具体数据：Specific data for the following monophasic pulses:
刺激脉冲的幅度、脉宽均可调，如图4所示。The amplitude and pulse width of the stimulation pulse can be adjusted, as shown in Figure 4.
采用脉冲串形式，刺激频率1-1000Hz，如图5所示。The form of pulse train is adopted, and the stimulation frequency is 1-1000 Hz, as shown in Fig. 5 .
双相脉冲：双相是指刺激脉冲有两个相位，正负对称，如图6所示。Biphasic pulse: Biphasic means that the stimulation pulse has two phases, positive and negative symmetrical, as shown in Figure 6.
下面结合实施例对本发明进行详细说明。The present invention will be described in detail below in conjunction with examples.
实施例1Example 1
本实施例的电刺激系统用作在心肌不应期，采用高能电刺激治疗慢性心力衰竭；The electrical stimulation system of this embodiment is used to treat chronic heart failure with high-energy electrical stimulation during the myocardial refractory period;
电刺激器系统包括位于体内的植入体刺激器、电极，以及位于体外的处理器和充电器；The electrical stimulator system includes an implanted stimulator and electrodes located inside the body, and a processor and charger located outside the body;
植入体刺激器包括：Implant stimulators include:
刺激单元，用于产生刺激电压源；a stimulation unit, used to generate a stimulation voltage source;
一组置于右心房的双极起搏器电极，用于检测心电信号；A set of bipolar pacemaker electrodes placed in the right atrium to detect electrical signals from the heart;
一组或两组置于右心室的双极起搏器电极，用于检测心电信号并产生高能电刺激；One or two sets of bipolar pacemaker electrodes placed in the right ventricle to detect electrical signals from the heart and generate high-energy electrical stimulation;
传感器，包括固定在刺激器壳体上，用于感知人体动作的加速度计传感器以及固定在目标器官上，用于感知器官表面肌肉运动或器官内部血流的压力传感器；Sensors, including accelerometer sensors fixed on the stimulator shell for sensing human body movements and pressure sensors fixed on the target organ for sensing muscle movement on the surface of the organ or blood flow inside the organ;
感知单元，用于对传感器采集的信息进行自适应放大；The perception unit is used to adaptively amplify the information collected by the sensor;
体内充电单元，用于为体内系统供电；an in-body charging unit for powering the in-body system;
体内通讯单元，用于与体外系统进行通讯；an in vivo communication unit for communicating with an in vitro system;
信号存储与处理单元，用于存储电极采集到的人体生理数据，并根据不同的应用产生不同的刺激；The signal storage and processing unit is used to store the human physiological data collected by the electrodes and generate different stimuli according to different applications;
控制与电压转换单元，用于将电池电压转换为系统工作所需电压，并控制整个体内系统运转；The control and voltage conversion unit is used to convert the battery voltage into the voltage required by the system and control the operation of the entire internal system;
体外的充电器用于对体内充电单元进行充电，并获得体内充电相关信息，将这些信息与处理器通讯；The charger outside the body is used to charge the charging unit inside the body, and obtain information related to charging inside the body, and communicate this information with the processor;
体外的处理器用于可调参数的输入，并通过无线通讯写入体内的信号存储与处理单元；同时，读取体内系统存储的信息。The processor outside the body is used for inputting adjustable parameters, which are written into the signal storage and processing unit inside the body through wireless communication; at the same time, the information stored in the system inside the body is read.
高能电刺激是由双相脉冲构成的一组脉冲串；每组脉冲串包括3-10对双相脉冲；双相脉冲振幅约为5-10V，且振幅调整不大于0.5V；High-energy electrical stimulation is a group of pulse trains composed of biphasic pulses; each group of pulse trains includes 3-10 pairs of biphasic pulses; the amplitude of biphasic pulses is about 5-10V, and the amplitude adjustment is not greater than 0.5V;
植入体刺激通路包括1-2路电压源；The implant stimulation pathway includes 1-2 voltage sources;
植入体测量通路包括1-2路测量电路，AD分辨率大于等于12bit，采样率1kHz；测量电路放大倍数100-1200可调，滤波器截止频率0.05-100Hz可调；The implant measurement channel includes 1-2 measurement circuits, the AD resolution is greater than or equal to 12bit, and the sampling rate is 1kHz; the measurement circuit magnification is adjustable from 100-1200, and the filter cut-off frequency is adjustable from 0.05-100Hz;
所述监测与刺激方法：在检测通路检测到了心肌不应期产生时(QRS波开始时)，刺激通路开始产生一组高能脉冲串(作用在右心室)。这样既不会影响正常的心电活动，又不会诱发室性心律失常。可通过处理器设置监测到不应期与刺激开始的延迟时间。但要确保刺激在不应期内发放完毕。一个典型的电刺激是一组6个脉冲(持续时长约30ms)，双相脉冲振幅7.5伏。The monitoring and stimulation method: when the detection pathway detects the generation of myocardial refractory period (when the QRS wave begins), the stimulation pathway starts to generate a group of high-energy pulse trains (acting on the right ventricle). This will neither affect the normal electrical activity of the heart nor induce ventricular arrhythmia. The delay time between the monitored refractory period and the onset of stimulation can be set by the processor. But make sure the stimulus is delivered within the refractory period. A typical electrical stimulation is a set of 6 pulses (approximately 30 ms in duration) with a biphasic pulse amplitude of 7.5 volts.
实施例2Example 2
本实施例的电刺激系统是一种治疗肥胖症及二型糖尿病治疗的植入式电刺激系统。The electrical stimulation system of this embodiment is an implantable electrical stimulation system for treating obesity and type 2 diabetes.
电刺激器系统包括位于体内的植入体刺激器、电极，以及位于体外的处理器和充电器；The electrical stimulator system includes an implanted stimulator and electrodes located inside the body, and a processor and charger located outside the body;
植入体刺激器包括：Implant stimulators include:
刺激单元，用于产生刺激电流源；a stimulating unit, used to generate a stimulating current source;
一组或两组至于胃窦的双极分叉电极，用于检测胃慢波信号，并释放高能量刺激与/或低能量刺激；One or two sets of bipolar bipolar electrodes on the gastric antrum to detect gastric slow wave signals and release high-energy stimulation and/or low-energy stimulation;
一条至于胃靠近食道部位的3维动态传感器，通过检测胃顶部的肌肉相对位置变化来检测进食事件；A 3D dynamic sensor on the stomach near the esophagus, which detects eating events by detecting changes in the relative position of the muscles at the top of the stomach;
固定在刺激器壳体上，用于感知人体动作的加速度计传感器；An accelerometer sensor fixed on the stimulator shell for sensing human motion;
感知单元，用于对传感器采集的信息进行自适应放大；The perception unit is used to adaptively amplify the information collected by the sensor;
体内充电单元，用于为体内系统供电；an in-body charging unit for powering the in-body system;
体内通讯单元，用于与体外系统进行通讯；an in vivo communication unit for communicating with an in vitro system;
信号存储与处理单元，用于存储电极采集到的人体生理数据，并根据不同的应用产生不同的刺激；The signal storage and processing unit is used to store the human physiological data collected by the electrodes and generate different stimuli according to different applications;
控制与电压转换单元，用于将电池电压转换为系统工作所需电压，并控制整个体内系统运转；The control and voltage conversion unit is used to convert the battery voltage into the voltage required by the system and control the operation of the entire internal system;
置于体外的充电器用于对体内充电单元进行充电，并获得体内充电相关信息，将这些信息与处理器通讯；The charger placed outside the body is used to charge the charging unit in the body, and obtain information related to charging in the body, and communicate the information with the processor;
置于体外的处理器用于可调参数的输入，并通过无线通讯写入体内的信号存储与处理单元；同时，读取体内系统存储的信息。The processor placed outside the body is used for the input of adjustable parameters, which are written into the signal storage and processing unit in the body through wireless communication; at the same time, the information stored in the system in the body is read.
治疗方法：在检测到进食事件时，产生高能双相刺激；平时产生低能量单相脉冲串刺激。Treatment: high-energy biphasic stimulation when a feeding event is detected; low-energy monophasic burst stimulation at ordinary times.
高能/进食部分：High energy/feeding portion:
所述高能电刺激是由双相脉冲构成的一组脉冲串；每组脉冲串包括3-10对双相脉冲；双相脉冲振幅约为5-15mA，且振幅调整不大于0.6mA；The high-energy electrical stimulation is a group of pulse trains composed of biphasic pulses; each group of pulse trains includes 3-10 pairs of biphasic pulses; the amplitude of the biphasic pulses is about 5-15mA, and the amplitude adjustment is not greater than 0.6mA;
植入体刺激通路包括1-4路电流源；Implant stimulation pathways include 1-4 current sources;
植入体测量通路包括1-4路测量电路，AD分辨率大于等于12bit，采样率1kHz；测量电路放大倍数100-1200可调，滤波器截止频率0.05-100Hz可调；The implant measurement channel includes 1-4 measurement circuits, the AD resolution is greater than or equal to 12bit, and the sampling rate is 1kHz; the measurement circuit magnification is adjustable from 100-1200, and the filter cut-off frequency is adjustable from 0.05-100Hz;
本实施例的监测与刺激方法：在检测通路检测到了胃部平滑肌肌不应期产生时(胃慢波的上升期)，刺激通路开始产生一组高能脉冲串。这样不会打断正常的胃电活动。可以通过处理器设置监测到不应期与刺激开始的延迟时间。但要确保刺激在不应期内发放完毕。一个典型的电刺激是一组5-10个脉冲，双相脉冲振幅7.5mA。最终达到的效果就是胃的慢波幅度被人为的增强了，增加了胃的收缩力。The monitoring and stimulation method of this embodiment: when the detection channel detects the generation of gastric smooth muscle refractory period (rising period of gastric slow wave), the stimulation channel starts to generate a group of high-energy pulse trains. This will not interrupt the normal electrical activity of the stomach. The delay time between detection of refractory period and stimulus onset can be set by processor. But make sure the stimulus is delivered within the refractory period. A typical electrical stimulation is a set of 5-10 pulses with a biphasic pulse amplitude of 7.5 mA. The final effect is that the slow wave amplitude of the stomach is artificially enhanced, increasing the contractility of the stomach.
以上监测与刺激方法仅仅在传感器检测到进食事件之后触发。一旦被触发，将维持一个时长60-90分钟的胃部收缩力增强刺激。The above monitoring and stimulation method is only triggered after the sensor detects an eating event. Once triggered, a gastric contractility enhancing stimulus is maintained for 60-90 minutes.
低能/平时部分：Low energy/normal part:
在平时，胃部维持一个脉宽大于1ms的单相脉冲串，其刺激率为30-100Hz，刺激幅度为5-10mA，这个刺激用于抑制胃动力，刺激将维持2s刺激，2s停止。一个典型的电刺激是脉宽为3-5ms，刺激率为50Hz，刺激幅度为6mA。In normal times, the stomach maintains a monophasic pulse train with a pulse width greater than 1ms, the stimulation rate is 30-100Hz, and the stimulation amplitude is 5-10mA. This stimulation is used to inhibit gastric motility. The stimulation will last for 2s and stop for 2s. A typical electrical stimulation has a pulse width of 3-5ms, a stimulation rate of 50Hz, and a stimulation amplitude of 6mA.
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| CN201710554053.1APendingCN107261324A (en) | 2017-07-09 | 2017-07-09 | Egersimeter system with charge function |
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