技术领域technical field
本发明涉及医疗器械技术领域，尤其是涉及一种引流型柔性微型支架及医疗器械。The invention relates to the technical field of medical devices, in particular to a drainage type flexible micro-stent and a medical device.
背景技术Background technique
目前，青光眼是一种在眼睛内的房水增加的疾病。在健康的眼睛中，睫状突分泌房水，然后房水穿过角膜和虹膜之间的角。青光眼看来像是小梁网阻塞的结果。这样的阻塞可以由细胞或其它残骸的脱落引起。当房水不从阻塞的网中适当地排出时，它就会增加而造成眼睛中，特别是在通向视神经的血管上的压力的增高。血管上的高压会导致视网膜神经节细胞死亡，并最终导致失明。Currently, glaucoma is a disease in which aqueous humor in the eye increases. In a healthy eye, the ciliary processes secrete aqueous humor, which then passes through the corner between the cornea and iris. Glaucoma appears to be the result of obstruction of the trabecular meshwork. Such blockage can be caused by the shedding of cells or other debris. When aqueous humor is not drained properly from the blocked mesh, it builds up causing increased pressure in the eye, especially on the blood vessels leading to the optic nerve. High pressure on blood vessels can cause retinal ganglion cells to die and eventually lead to blindness.
相关技术中，针对青光眼的外科手术治疗时会在眼中植入一种引流装置或分流管。该引流装置的作用是从前房排出房水，从而降低眼内压力。该引流装置典型地利用创伤性外科手术方法而植入。按照一个这样的手术，在巩膜中以外科方式形成一个薄片。该薄片向后折叠形成一个小的空洞，一个分流管通过该薄片嵌入眼中。这样的手术会因其植入体大而有较强的创伤性，并且会引起各种不良事件，例如感染和留下疤痕，导致需要重新进行手术。In the related art, a drainage device or shunt tube is implanted in the eye during surgical treatment of glaucoma. The purpose of this drainage device is to drain the aqueous humor from the anterior chamber, thereby reducing the pressure in the eye. The drainage device is typically implanted using invasive surgical methods. According to one such procedure, a thin flap is surgically formed in the sclera. The sheet is folded back to form a small cavity through which a shunt is inserted into the eye. Such surgery can be traumatic due to the large size of the implant, and can cause various adverse events, such as infection and scarring, leading to the need for reoperation.
目前用于治疗青光眼的装置和过程存在一些缺点，并且仅有中等的成功率。这种过程对眼睛有很大的创伤，还要求非常精确的外科技巧，例如在适当的位置适当地放置引流装置。此外，从前房到位于巩膜薄片下的结膜下水泡的引流的这种装置易于造成感染，并且可能堵塞和停止操作。这可能要求重新进行手术以移走该装置，并放置另一个装置，或者会导致进一步的外科手术。考虑到上述原因，需要改进用于治疗青光眼的装置和方法。The devices and procedures currently used to treat glaucoma suffer from several disadvantages and have only moderate success rates. This procedure is traumatic to the eye and requires very precise surgical skills, such as proper placement of the drainage device in the proper location. Furthermore, such devices that drain from the anterior chamber to subconjunctival vesicles located under the scleral lamina are prone to infection and possible blockage and cessation of operation. This may require reoperation to remove the device and place another, or may result in further surgery. In view of the foregoing, there is a need for improved devices and methods for treating glaucoma.
当然，相关技术中也有一些专利文献提及类似引流管的介绍，结合图1所示，分流管105设置于眼睛内，房水从前房115进入分流管105后流向脉络膜上腔。但是，该分流管仅仅只是提供一个流体通路，存在以下两点缺陷：Of course, there are some patent documents in the related art that mention the introduction of similar drainage tubes. As shown in FIG. 1 , the shunt tube 105 is set in the eye, and the aqueous humor enters the shunt tube 105 from the anterior chamber 115 and then flows to the suprachoroidal space. However, the shunt tube only provides a fluid path, and has the following two defects:
一、单腔分流管长时间的植入有可能在肌肉的压力下发生形变，导致管腔坍塌堵塞；1. Long-term implantation of the single-lumen shunt may deform under the pressure of the muscle, resulting in collapse and blockage of the lumen;
二、分流管在植入后，有可能会导致局部位置发生增殖和发炎的情况，产生其他的病变。2. After the shunt is implanted, it may cause proliferation and inflammation in the local area, and other lesions may occur.
发明内容Contents of the invention
本发明的目的在于提供一种引流型柔性微型支架及医疗器械，以解决现有技术中存在的单腔分流管长时间的植入有可能在肌肉的压力下发生形变，导致管腔坍塌堵塞；分流管在植入后，有可能会导致局部位置发生增殖和发炎的情况，产生其他的病变的技术问题。The purpose of the present invention is to provide a drainage-type flexible micro-stent and a medical device to solve the problem in the prior art that the single-lumen shunt may be deformed under the pressure of the muscle after being implanted for a long time, resulting in collapse and blockage of the lumen; After the shunt is implanted, it may cause proliferation and inflammation in the local area, and cause other technical problems of pathological changes.
为解决上述技术问题，本发明提供一种引流型柔性微型支架，其包括多腔型的引流管，所述多腔型的引流管沿着从前房眼睛的巩膜突进入脉络膜上腔内的路径穿过，其中，所述多腔型的引流管至少包括：In order to solve the above technical problems, the present invention provides a drainage-type flexible micro-stent, which includes a multi-lumen drainage tube, and the multi-lumen drainage tube passes through the path from the scleral protrusion of the anterior chamber eye into the suprachoroidal space. However, wherein the multi-lumen drainage tube at least includes:
一个流体通路，所述流体通路沿所述引流管的中心贯通设置，其具有流入口和流出口；A fluid passage, the fluid passage is arranged through the center of the drainage tube, and it has an inflow port and an outflow port;
多个药物填充腔，多个所述药物填充腔设置于所述流体通路的外围，且分别沿所述引流管的周向贯通设置；A plurality of drug-filled cavities, the plurality of drug-filled cavities are arranged on the periphery of the fluid passage, and are respectively arranged through the circumferential direction of the drainage tube;
多个药物释放孔，多个所述药物释放孔均开设于所述引流管的外壁上，且与其所对应位置的药物填充腔相连。A plurality of drug release holes are all opened on the outer wall of the drainage tube and connected to the drug filling cavity at the corresponding position.
进一步地，所述药物填充腔的内部设有用于存放药物的填充空间，所述药物通过超声雾化的形式填充于所述药物填充腔内部的填充空间内。Further, a filling space for storing medicine is provided inside the medicine filling chamber, and the medicine is filled into the filling space inside the medicine filling chamber in the form of ultrasonic atomization.
进一步地，所述药物包括：丝裂霉素、肝霉素、肝素混、雷帕霉素、聚乳酸、聚乙醇酸共聚物、聚碳酸酯、磷酸胆碱、含氟聚合物中的一种或任意几种组合。Further, the drug includes: one of mitomycin, heparin, heparin mixture, rapamycin, polylactic acid, polyglycolic acid copolymer, polycarbonate, phosphorylcholine, and fluoropolymer or any combination of several.
进一步地，所述流体通路的截面形状为圆形、椭圆形或者矩形。Further, the cross-sectional shape of the fluid channel is circular, elliptical or rectangular.
进一步地，所述药物填充腔的截面形状为扁平状。Further, the cross-sectional shape of the medicine filling cavity is flat.
进一步地，所述药物填充腔的数量为五个。Further, the number of the medicine filling cavities is five.
进一步地，所述引流管采用生物相容性材料制成。Further, the drainage tube is made of biocompatible materials.
进一步地，所述引流管的外壁上设置有限位组件，所述限位组件用于固定所述引流管在使用状态的相对位置。Further, a limiting component is provided on the outer wall of the drainage tube, and the limiting component is used to fix the relative position of the drainage tube in the use state.
进一步地，所述引流管的外壁上设置有标识组件，所述标识组件用于标记所述引流管在使用状态的相对位置。Further, an identification component is provided on the outer wall of the drainage tube, and the identification component is used to mark the relative position of the drainage tube in a state of use.
为解决上述技术问题，本发明还提供一种医疗器械，其包括输送装置，所述输送装置用于输送所述的引流型柔性微型支架，其同样包括多腔型的引流管，所述多腔型的引流管沿着从前房眼睛的巩膜突进入脉络膜上腔内的路径穿过，其中，所述多腔型的引流管至少包括：一个流体通路、多个药物填充腔和多个药物释放孔；所述流体通路沿所述引流管的中心贯通设置，其具有流入口和流出口；多个所述药物填充腔设置于所述流体通路的外围，且分别沿所述引流管的周向贯通设置；多个所述药物释放孔均开设于所述引流管的外壁上，且与其所对应位置的药物填充腔相连。In order to solve the above technical problems, the present invention also provides a medical device, which includes a delivery device, which is used to deliver the drainage-type flexible micro-stent, which also includes a multi-lumen drainage tube, and the multi-lumen The multi-lumen type drainage tube passes along the path from the scleral process of the anterior chamber eye into the suprachoroidal space, wherein the multi-lumen type drainage tube at least includes: a fluid passage, a plurality of drug filling cavities and a plurality of drug release holes The fluid passage is provided through the center of the drainage tube, which has an inlet and an outlet; a plurality of the drug filling chambers are arranged on the periphery of the fluid passage, and are respectively penetrated along the circumference of the drainage tube Setting; a plurality of drug release holes are all opened on the outer wall of the drainage tube, and connected to the drug filling cavity at the corresponding position.
采用上述技术方案，本发明具有如下有益效果：Adopt above-mentioned technical scheme, the present invention has following beneficial effect:
本发明提供一种引流型柔性微型支架，在眼睛的角膜上形成一个切口，将该微型支架经过该切口固定在眼睛的前房内。该微型支架沿着从前房眼睛的巩膜突进入脉络膜上腔内的路径穿过，微型支架的流体通路通过引导前房的房水流入脉络膜上腔以达到降低眼内压的目的。同时，药物填充腔能够将药物有效、持久地在固定位置进行释放，大大的减小了固定位置增殖和发炎的情况。The invention provides a drainage type flexible micro-stent, an incision is formed on the cornea of the eye, and the micro-stent is fixed in the anterior chamber of the eye through the incision. The micro-stent passes along the path from the scleral protrusion of the anterior chamber eye into the suprachoroidal space, and the fluid passage of the micro-stent guides the aqueous humor in the anterior chamber to flow into the suprachoroidal space to reduce the intraocular pressure. At the same time, the drug-filled cavity can effectively and permanently release the drug at the fixed position, greatly reducing the proliferation and inflammation of the fixed position.
附图说明Description of drawings
为了更清楚地说明本发明具体实施方式或现有技术中的技术方案，下面将对具体实施方式或现有技术描述中所需要使用的附图作简单的介绍，显而易见地，下面描述中的附图是本发明的一些实施方式，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings that need to be used in the description of the specific embodiments or the prior art. Obviously, the accompanying drawings in the following description The drawings show some implementations of the present invention, and those skilled in the art can obtain other drawings based on these drawings without any creative work.
图1为眼睛的前房和后房的一部分眼睛的剖视立体图；Figure 1 is a cutaway perspective view of a part of the anterior chamber and posterior chamber of the eye;
图2为眼睛的横截面视图；Figure 2 is a cross-sectional view of the eye;
图3为本发明实施例提供的引流型柔性微型支架的结构示意图；Figure 3 is a schematic structural view of a drainage-type flexible micro-stent provided by an embodiment of the present invention;
图4为本发明实施例提供的引流型柔性微型支架的侧面示意图。Fig. 4 is a schematic side view of a drainage-type flexible micro-stent provided by an embodiment of the present invention.
附图标记：Reference signs:
1-流体通路； 2-药物填充腔； 3-药物释放孔。1 - fluid pathway; 2 - drug filling cavity; 3 - drug release hole.
具体实施方式detailed description
下面将结合附图对本发明的技术方案进行清楚、完整地描述，显然，所描述的实施例是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。The technical solutions of the present invention will be clearly and completely described below in conjunction with the accompanying drawings. Apparently, the described embodiments are some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
在本发明的描述中，需要说明的是，术语“中心”、“上”、“下”、“左”、“右”、“竖直”、“水平”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。此外，术语“第一”、“第二”、“第三”仅用于描述目的，而不能理解为指示或暗示相对重要性。In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, or in a specific orientation. construction and operation, therefore, should not be construed as limiting the invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and should not be construed as indicating or implying relative importance.
在本发明的描述中，需要说明的是，除非另有明确的规定和限定，术语“安装”、“相连”、“连接”应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或一体地连接；可以是机械连接，也可以是电连接；可以是直接相连，也可以通过中间媒介间接相连，可以是两个元件内部的连通。对于本领域的普通技术人员而言，可以根据具体情况理解上述术语在本发明中的具体含义。In the description of the present invention, it should be noted that unless otherwise specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection. Connected, or integrally connected; it can be mechanically connected or electrically connected; it can be directly connected or indirectly connected through an intermediary, and it can be the internal communication of two components. Those of ordinary skill in the art can understand the specific meanings of the above terms in the present invention according to specific situations.
以下结合附图对本发明的具体实施方式进行详细说明。应当理解的是，此处所描述的具体实施方式仅用于说明和解释本发明，并不用于限制本发明。Specific embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings. It should be understood that the specific embodiments described here are only used to illustrate and explain the present invention, and are not intended to limit the present invention.
实施例一Embodiment one
为了方便理解，在介绍本实施例之间先对眼睛的前房和后房的构造进行简单描述。结合图2所示，眼睛一般是球状的，并且由巩膜S覆盖其外。视网膜R布满在眼睛内的后半部分内。视网膜记录光，并经由视神经发送信号到大脑。眼睛大部分由玻璃体所充满和支撑，玻璃体是一种清澈的、果冻状的物质。For the convenience of understanding, before introducing this embodiment, the structure of the anterior chamber and the posterior chamber of the eye will be briefly described. As shown in FIG. 2 , the eye is generally spherical and covered by the sclera S. The retina R covers the posterior half of the eye. The retina records light and sends signals to the brain via the optic nerve. The eye is mostly filled and supported by the vitreous, a clear, jelly-like substance.
弹性晶状体L位于眼睛前部附近。晶状体L提供焦点的调整，并且被悬挂在来自睫状体CB的囊袋内，睫状体CB包含改变晶状体焦距的肌肉。晶状体L前面的空间被虹膜I分割成两部分，虹膜控制晶状体的孔径和到达视网膜的光量。瞳孔是位于虹膜I中心的一个孔，光经由瞳孔通过。在虹膜I和晶状体L之间的空间是后房PC。在虹膜I和角膜之间的空间是前房AC。前房和后房充满被称为房水的清澈的流体。The elastic lens L is located near the front of the eye. The lens L provides adjustment of focus and is suspended within a capsular bag from the ciliary body CB, which contains the muscles that change the focal length of the lens. The space in front of the lens L is divided in two by the iris I, which controls the aperture of the lens and the amount of light that reaches the retina. The pupil is a hole in the center of the iris I through which light passes. The space between the iris I and the lens L is the posterior chamber PC. The space between the iris I and the cornea is the anterior chamber AC. The anterior and posterior chambers are filled with a clear fluid called aqueous humor.
睫状体CB通过来自血管的分泌物不断地在后房PC中形成房水。房水在晶状体L和虹膜I周围流动进入前房，并通过小梁网离开眼睛，小梁网是一种位于虹膜I和眼球壁的角(该角也被称为房角)的筛状结构。一些房水通过小梁网过滤进入Schlemm氏管，Schlemm氏管是引流进入眼睛静脉的一条小通道。更小部分在经过睫状体，并最终经过巩膜(巩膜路线)之后再次加入静脉循环。The ciliary body CB continuously forms aqueous humor in the posterior chamber PC through secretions from blood vessels. Aqueous humor flows around the lens L and iris I into the anterior chamber and exits the eye through the trabecular meshwork, a sieve-like structure at the corner of the iris I and eye wall (this angle is also called the angle of the chamber) . Some of the aqueous humor filters through the trabecular meshwork into Schlemm's canal, a small channel that drains into the veins of the eye. A smaller portion rejoins the venous circulation after passing through the ciliary body and eventually the sclera (scleral route).
如图3、图4所示，本实施例一提供的引流型柔性微型支架，其包括多腔型的引流管，所述多腔型的引流管沿着从前房眼睛的巩膜突进入脉络膜上腔内的路径穿过，其中，所述多腔型的引流管至少包括：As shown in Figure 3 and Figure 4, the drainage-type flexible micro-stent provided by the first embodiment includes a multi-chamber drainage tube, and the multi-chamber drainage tube enters the suprachoroidal space along the scleral protrusion of the anterior chamber eye The inner path passes through, wherein the multi-lumen drainage tube at least includes:
一个流体通路1，所述流体通路1沿所述引流管的中心贯通设置，其具有流入口和流出口，该流体通路1通过引导前房的房水流入脉络膜上腔以达到降低眼内压的目的。A fluid channel 1, the fluid channel 1 is arranged through the center of the drainage tube, it has an inflow port and an outflow port, the fluid channel 1 can reduce the intraocular pressure by guiding the aqueous humor in the anterior chamber to flow into the suprachoroidal space Purpose.
多个药物填充腔2，多个所述药物填充腔2设置于所述流体通路1的外围，且分别沿所述引流管的周向贯通设置，药物填充腔2能够将药物有效、持久地在固定位置进行释放，大大的减小了固定位置增殖和发炎的情况；A plurality of medicine filling chambers 2, a plurality of medicine filling chambers 2 are arranged on the periphery of the fluid passage 1, and are respectively arranged through the circumferential direction of the drainage tube, the medicine filling chambers 2 can effectively and durably store medicine in the Release at a fixed position, greatly reducing the proliferation and inflammation of the fixed position;
多个药物释放孔3，多个所述药物释放孔3均开设于所述引流管的外壁上，且与其所对应位置的药物填充腔2相连。A plurality of drug release holes 3 are provided on the outer wall of the drainage tube and connected to the drug filling cavity 2 at the corresponding position.
可见，本实施例一种的多腔型的引流管，中间空心允许房水通过，多孔又能保证材料的足够韧性，使其能长时间保持房水引流功能不变形，药物填充腔2可以持续、稳定的释放药物减小支架固定位置发生病变的几率。It can be seen that the multi-chamber drainage tube of this embodiment is hollow in the middle to allow aqueous humor to pass through, and the holes can ensure sufficient toughness of the material, so that it can maintain the aqueous humor drainage function without deformation for a long time, and the drug filling cavity 2 can continue , Stable drug release reduces the probability of lesions occurring at the fixed position of the stent.
该引流型柔性微型支架，在所述药物填充腔2的内部设有用于存放药物的填充空间，所述药物通过超声雾化的形式填充于所述药物填充腔2内部的填充空间内。The drainage-type flexible micro-stent has a filling space for storing medicine inside the medicine filling cavity 2 , and the medicine is filled in the filling space inside the medicine filling cavity 2 in the form of ultrasonic atomization.
具体地，所述药物包括：丝裂霉素、肝霉素、肝素混、雷帕霉素、聚乳酸、聚乙醇酸共聚物、聚碳酸酯、磷酸胆碱、含氟聚合物中的一种或任意几种组合。Specifically, the drug includes: one of mitomycin, heparin, heparin, rapamycin, polylactic acid, polyglycolic acid copolymer, polycarbonate, phosphorylcholine, and fluoropolymer or any combination of several.
对于引流型柔性微型支架的具体结构以及尺寸大小，可根据实际情况灵活调整。下面以其中几种优选的实例进行说明。The specific structure and size of the drainage-type flexible micro-stent can be flexibly adjusted according to the actual situation. Several preferred examples thereof will be described below.
优选地，所述流体通路1的截面形状为圆形、椭圆形或者矩形。在本实施例中流体通路1的截面形状为圆形。Preferably, the cross-sectional shape of the fluid channel 1 is circular, oval or rectangular. In this embodiment, the cross-sectional shape of the fluid channel 1 is circular.
优选地，所述药物填充腔2的截面形状为扁平状。例如：其形状为两头扁尖的长圆形，当然其他形状也可以，此处不再一一列举。Preferably, the cross-sectional shape of the medicine filling chamber 2 is flat. For example: the shape is an oblong shape with flat ends at both ends, and of course other shapes are also possible, which will not be listed one by one here.
具体地，所述药物填充腔2的数量为五个，五个药物填充腔2均匀地分布在所述流体通路1的四周。Specifically, the number of the medicine filling chambers 2 is five, and the five medicine filling chambers 2 are evenly distributed around the fluid passage 1 .
本实施例中，所述引流管采用生物相容性材料制成。In this embodiment, the drainage tube is made of biocompatible materials.
例如：所述引流管可以采用生物相容性好的聚酰亚胺、陶瓷、有机硅橡胶或者不锈钢或镍钛合金等等生物相容性材料。For example, the drainage tube can be made of biocompatible materials such as polyimide, ceramics, silicone rubber, stainless steel or nickel-titanium alloy with good biocompatibility.
当然，所述引流管也可以采用其他材料或材料，例如：其它适合的聚合物、金属、金属合金，或者它们的各种组合。其它加工材料或材料包括硅树脂、PTFE、各种含氟聚合物、FEP、层合成ePTFE的节点的FEP、银涂层(例如经由CVD工艺)、金、聚丙烯纺织纤维/聚烯烃、聚乙烯(异丁烯酸甲脂)(PMMA)、丙烯酸树脂、聚对苯二甲酸乙二醇酯(PET)、聚乙烯(PE)、PLLA和聚对二甲苯基等等。Of course, the drainage tube can also use other materials or materials, for example: other suitable polymers, metals, metal alloys, or various combinations thereof. Other process materials or materials include silicone, PTFE, various fluoropolymers, FEP, FEP layered into nodes of ePTFE, silver coating (e.g. via CVD process), gold, polypropylene textile fibers/polyolefins, polyethylene (methyl methacrylate) (PMMA), acrylic resin, polyethylene terephthalate (PET), polyethylene (PE), PLLA and parylene, etc.
进一步地，所述引流管的外壁上设置有限位组件，所述限位组件用于固定所述引流管在使用状态的相对位置。限位组件可以为突出体、翼状物、齿状物或叉状物，它们介入人体，以将引流管保持在正确位置。Further, a limiting component is provided on the outer wall of the drainage tube, and the limiting component is used to fix the relative position of the drainage tube in the use state. The stop components can be protrusions, wings, teeth or forks, which intervene in the body to keep the drainage tube in the correct position.
进一步地，所述引流管的外壁上设置有标识组件，所述标识组件用于标记所述引流管在使用状态的相对位置。所述引流管可以带有一个或多个可视的、断面扫描的、回声的或者不透射线的标识组件，标识组件可以通过将上面提及的任何一种装置调到其适用的标识系统来帮助定位。Further, an identification component is provided on the outer wall of the drainage tube, and the identification component is used to mark the relative position of the drainage tube in a state of use. The drain may be provided with one or more visual, cross-sectional scanning, echogenic or radiopaque marker assemblies which may be identified by adapting any of the above-mentioned devices to the appropriate marker system. Help with orientation.
实施例二Embodiment two
本实施例二提供一种医疗器械，其包括输送装置，所述输送装置用于输送实施例一所述的引流型柔性微型支架。The second embodiment provides a medical device, which includes a delivery device for delivering the drainage-type flexible micro-stent described in the first embodiment.
具体地，该引流型柔性微型支架包括多腔型的引流管，所述多腔型的引流管沿着从前房眼睛的巩膜突进入脉络膜上腔内的路径穿过，其中，所述多腔型的引流管至少包括：Specifically, the drainage-type flexible micro-stent includes a multi-lumen drainage tube, and the multi-lumen drainage tube passes along the path from the scleral process of the anterior chamber eye into the suprachoroidal space, wherein the multi-lumen drainage tube The drainage tube includes at least:
一个流体通路1，所述流体通路1沿所述引流管的中心贯通设置，其具有流入口和流出口，该流体通路1通过引导前房的房水流入脉络膜上腔以达到降低眼内压的目的。A fluid channel 1, the fluid channel 1 is arranged through the center of the drainage tube, it has an inflow port and an outflow port, the fluid channel 1 can reduce the intraocular pressure by guiding the aqueous humor in the anterior chamber to flow into the suprachoroidal space Purpose.
多个药物填充腔2，多个所述药物填充腔2设置于所述流体通路1的外围，且分别沿所述引流管的周向贯通设置，药物填充腔2能够将药物有效、持久地在固定位置进行释放，大大的减小了固定位置增殖和发炎的情况；A plurality of medicine filling chambers 2, a plurality of medicine filling chambers 2 are arranged on the periphery of the fluid passage 1, and are respectively arranged through the circumferential direction of the drainage tube, the medicine filling chambers 2 can effectively and durably store medicine in the Release at a fixed position, greatly reducing the proliferation and inflammation of the fixed position;
多个药物释放孔3，多个所述药物释放孔3均开设于所述引流管的外壁上，且与其所对应位置的药物填充腔2相连。A plurality of drug release holes 3 are provided on the outer wall of the drainage tube and connected to the drug filling cavity 2 at the corresponding position.
至于其他特征，已在上面详细描述，此处不再赘述。As for other features, they have been described in detail above and will not be repeated here.
最后应说明的是：以上各实施例仅用以说明本发明的技术方案，而非对其限制；尽管参照前述各实施例对本发明进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分或者全部技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本发明各实施例技术方案的范围。Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than limiting them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: It is still possible to modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the technical solutions of the various embodiments of the present invention. scope.
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| TA01 | Transfer of patent application right | Effective date of registration:20170714 Address after:430000, No. 2, No. 3, building B9, hi tech medical instrument Park, 818 hi tech Avenue, East Lake hi tech Development Zone, Wuhan, Hubei Applicant after:WEITONG (WUHAN) MEDICAL TECHNOLOGY CO.,LTD. Address before:2, building 2, unit 858, building A6, 433000 hi tech Avenue, East Lake hi tech Zone, Hubei, Wuhan Applicant before:WUHAN GREENOVO BIOTECHNOLOGY CO.,LTD. | |
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| RJ01 | Rejection of invention patent application after publication | Application publication date:20170721 |