A kind of oxygen closes drainage tube, oxygenation device and oxygen and closes methodTechnical field
The present invention relates to method is closed and in particular to a kind of oxygen closes drainage tube, oxygenation device and oxygen in oxygenation field.
Background technology
It is known that in human body, the deposit of oxygen is little just can sustain life it is necessary to continuously feed oxygen in a steady stream from the external world,Therefore from clinically initial mask oxygen inhalation to nose conduit, hyperbaric oxygen chamber and the Ventilators in succession occurring afterwards etc. allIt is conceived to by respiratory tract oxygen supply, and become the important means of various anoxia treatments.However, for some particular patients ', oftenRule oxygen supply method can seem helpless.Acute lung injury, traumatic such as in the face of being caused due to Serious respiratory tract burn etc.Hypertonicity pulmonary edema that hydropneumothorax, sea water cause, SARS etc. cause the patient of pulmonary diffusion function serious hindrance, and its subject matter is simultaneouslyDo not lie in dysfunction of ventilation, therefore usually cannot effectively save the life of patient through conventional respiratory tract oxygen supply；Meanwhile, special at someIn the case of, the restriction of conventional oxygen supply method also brings many obstacles to the rescue of patient.So, oxygen supply approach can be changed,Attempt being used as supplemental oxygen new method by even oral grade of vein, bypass this pass of alveolar of diffusing capacity and make oxygen straightTap into into blood？
In fact recent domestic never has and stops about the research of oxygen carrying succedaneum aspect, such as no substrate blood eggIn vain, genetic engineering artificial blood, the circulating protein solution of liposome parcel, perfluor carbon solution etc., but due to these product processComplicated, expensive, also have relatively large distance from technology maturation so far, be still difficult to use in clinic.And once should be used in ChinaLiquid oxygen charging method then includes light quantum blood therapy (UIB), blood-magent therapy, magnesium arginyl amine hydroperoxide Carbamide Peroxide method, light quantumLiquid treatment etc., but be also respectively present blood drawing oxygenation and feed back some defects such as loaded down with trivial details, the few, less stable of blood oxygen carrying content of operation.
Content of the invention
The present invention is to solve the above problems, and provides a kind of oxygen to close drainage tube, oxygenation device and oxygen and closes method.
The technical problem to be solved to be realized using following technical scheme：
A kind of oxygen closes drainage tube, and this oxygen closes drainage tube and is made up of and both central axis weights outer layer sleeve and inner layer sleeveClose, form oxygen therapy passage between described outer layer sleeve inwall and inner layer sleeve outer wall, oxygen therapy passage two ends face closure, in its right-hand memberFace is connected with oxygen catheter by flexible pipe, and left side is connected with outlet tube, and output pipe end is provided with check valve, and inner layer sleeve is by partlyAntireflective film material is made, and this semipermeable membrane allows gas molecule to flow from high concentration lateral low concentration side, and fluid molecule can not pass through, interiorLayer internal surface of sleeve pipe forms oxygen and closes passage, and oxygen closes passage in two end faces opening, respectively by entering blood vessel, going out blood vessel and be inserted into veinIn blood vessel, described enter blood vessel, go out blood vessel positioned at outer body length make blood from vein just out just can enter oxygen close passage.OxygenGas enters oxygen therapy passage by oxygen catheter, and blood enters oxygen against oxygen flow direction and closes passage, and oxygen passes through semipermeable membrane inner sleevePipe enters oxygen and closes passage and close the blood oxygenation in passage with oxygen, and the carbon dioxide of generation enters through semipermeable membrane inner sleeve and entersOxygen therapy passage is simultaneously discharged from discharge pipe end with unnecessary oxygen.
When oxygen closes the 0.6-0.8 that cross sectional area closes drainage tube area of section for oxygen, there is preferable oxygenation efficiency.
A kind of have the oxygenation device that oxygen closes drainage tube, including effusion meter, piezometer, controller, control panel；Described pressurePower meter is arranged in oxygen therapy passage and is connected with described controller, and controller is connected with control panel, and described effusion meter is arranged onIt is connected on oxygen catheter and with controller, effusion meter is used for controlling the oxygen flow being passed through in oxygen therapy passage, in the setting of oxygen catheter front endThere is bypass branch, equipped with control valve in bypass branch, control valve is connected with controller.When the oxygen pressure in oxygen therapy passage is higher than to setDuring definite value, the oxygen reduced pressure in oxygen therapy passage is made to turn off control valve to setting value by the opening angle of control valve.
A kind of vein extracorporeal oxygenation method, comprises the following steps：
1), described oxygen is closed entering blood vessel, going out blood vessel and be inserted respectively in vein blood vessel of drainage tube two ends, and carry out hemostasisThe back works such as sterilization；
2), the oxygen pressure being passed through in oxygen therapy passage is set on described control panel as a setting value；
3), described control panel transfers signals to controller, and controller controls effusion meter to open and into oxygen therapy passageConveying oxygen, the oxygen in oxygen therapy passage passes through semipermeable membrane inner sleeve to enter oxygen and closes passage and close the blood oxygen in passage with oxygenClose, the carbon dioxide of generation enters through semipermeable membrane inner sleeve and enters oxygen therapy passage and with unnecessary oxygen from discharge pipe end rowGo out, the blood completing oxygen conjunction enters into vein blood vessel from going out blood vessel, the oxygen pressure in the oxygen therapy passage of piezometer monitoring simultaneously, whenReach and during setting value, keep flow to be calculated as an opening angle, during oxygen closes, if the oxygen pressure that piezometer records occurs being higher thanSetting value, signal is first fed back to controller by piezometer, and controller sends opens control valve order, and control valve opens an angle simultaneouslyThe oxygen pressure in oxygen therapy passage is made to gradually reduce, when being reduced to setting value, controller sends closing control valve order, if occurringThe oxygen pressure that piezometer records is less than setting value, and signal is fed back to controller by piezometer, and controller sends increase effusion meter and opensOpen angle commands, the oxygen pressure in oxygen therapy passage is equal to setting value；
4), during oxygen conjunction, the blood inlet end blood oxygen concentration measuring instrument at oxygen conjunction passage blood inlet end and bleeding end, bleeding end bloodThe oxygen recording is closed the oxygen content in forward and backward blood and feeds back to controller and be shown in control panel by oxygen concentration testing instrument respectively,Medical personnel revise the setting value of oxygen pressure in oxygen therapy passage accordingly.
Beneficial effects of the present invention are：Logical peroxo drainage tube two ends enter blood vessel, go out blood vessel by blood drainage to oxygen closeClose in passage and with oxygen oxygen, bypass this pass of alveolar of diffusing capacity and allow oxygen be directly entered blood and hemoglobinOxygen closes, and produced carbon dioxide passes through semipermeable membrane inner sleeve and unnecessary oxygen to discharge from output pipe end, declines in pulmonary functionExhaust or temporarily can not play and can preferably replace pulmonary during Oxygenation, with membrane oxygenator, oxygen carrying succedaneum or liquidBody oxygen charging method is compared, and this apparatus structure is simple, easy to use, and blood drainage occurs oxygen to close with oxygen to external at once, and blood is takenOxygen content is high, stability is preferable.
Brief description
Fig. 1 is schematic diagram of the present invention；
Fig. 2 closes drainage tube drawing in side sectional elevation for oxygen of the present invention.
Specific embodiment
In order that technological means, creation characteristic, reached purpose and effect that the present invention realizes are easy to understand, tie belowClose embodiment, the present invention is expanded on further.
As shown in Figure 1, 2, oxygen closes drainage tube 2 and is made up of and both central axis weights outer layer sleeve 2C and inner layer sleeve 2DClose, form oxygen therapy passage 2A between outer layer sleeve 2C inwall and inner layer sleeve 2D outer wall, oxygen therapy passage two ends face closure, on its right sideEnd face is connected with oxygen catheter 9 by flexible pipe 12, and left side is connected with outlet tube 2B, and outlet tube 2B end is provided with check valve 13,Wherein inner layer sleeve 2D is made up of semipermeable membrane material, and this semipermeable membrane allows gas molecule to flow from high concentration lateral low concentration side,Fluid molecule can not pass through, and inner layer sleeve 2D inwall forms oxygen and closes passage 2E, and oxygen closes passage 2E in two end faces opening, leads to respectivelyCross into blood vessel, go out blood vessel and be inserted in vein, enter blood vessel, go out blood vessel and from vein just out make blood positioned at outer body lengthOxygen can be entered and close passage 2E, oxygen passes through oxygen catheter 9 and enters oxygen therapy passage 2A, blood closes against oxygen flow direction entrance oxygen logicalRoad 2E, oxygen pass through semipermeable membrane inner sleeve 2D enter oxygen close passage 2E and with oxygen close passage 2E in blood oxygenation, the two of generationCarbonoxide enters through semipermeable membrane inner sleeve 2D and enters oxygen therapy passage 2A and discharge from discharge pipe 2B end with unnecessary oxygen.
In oxygen therapy passage 2A, piezometer 3 is installed, piezometer 3 is connected with controller 6, controller 6 is with control panel 7 evenConnect, piezometer 3 is used for oxygen pressure by the data feedback recording to controller in monitor in real time oxygen therapy passage 2A, on oxygen catheter 9Effusion meter 8 is installed, effusion meter 8 is used for controlling the oxygen flow being passed through in oxygen therapy passage 2A, and effusion meter 8 is connected with controller 6,Oxygen catheter 9 front end is provided with bypass branch 11, and equipped with control valve 10 in bypass branch 11, control valve 10 is connected with controller 6, whenWhen oxygen pressure in oxygen therapy passage 2A is higher than setting value, the oxygen pressure in oxygen therapy passage 2A is made by the opening angle of control valve 10It is reduced to setting value and turn off control valve 10.
Close passage 2E blood inlet end in oxygen and bleeding end is respectively arranged with blood inlet end blood oxygen concentration measuring instrument 5, bleeding end blood oxygenConcentration measuring apparatus 4, blood inlet end blood oxygen concentration measuring instrument 5, bleeding end blood oxygen concentration measuring instrument 4 are connected respectively to controller 6.
When oxygen closes the 0.6-0.8 that passage 2E area of section closes drainage tube 2 area of section for oxygen, there is preferable oxygen and close effectRate.
A kind of vein extracorporeal oxygenation method, comprises the following steps：
1), oxygen is closed entering blood vessel, going out blood vessel and be inserted respectively in vein blood vessel 1 of drainage tube 2 two ends, and carry out hemostasis and disappearThe back works such as poison；
2), the oxygen pressure being passed through in oxygen therapy passage 2A is set on control panel 7 as a setting value；
3), control panel 7 transfers signals to controller 6, and controller 6 controls effusion meter 8 to open and to oxygen therapy passage 2AInterior conveying oxygen, the oxygen in oxygen therapy passage 2A is passed through semipermeable membrane inner sleeve 2D to enter oxygen and closes passage 2E and closed in passage 2E with oxygenBlood oxygenation, the carbon dioxide of generation enter through semipermeable membrane inner sleeve 2D enter oxygen therapy passage 2A and with unnecessary oxygen fromDischarge pipe 2B end is discharged, and the blood completing oxygen conjunction enters into vein blood vessel from going out blood vessel, and the oxygen therapy of piezometer 3 monitoring simultaneously is logicalOxygen pressure in road 2A, keeps effusion meter 8 to be an opening angle, during oxygen closes, if pressure when reaching setting valueThe oxygen pressure that meter 3 records is higher than setting value, and signal is first fed back to controller 6 by piezometer 3, and controller 6 sends opens control valve10 orders, control valve 10 is opened an angle and so that the oxygen pressure in oxygen therapy passage 2A is gradually reduced, when being reduced to setting value, controlDevice 6 processed sends closing control valve 10 and orders, if the oxygen pressure that piezometer 3 records to be less than setting value, piezometer 3 is anti-by signalIt is fed to controller 6, controller 6 sends increase effusion meter 8 opening angle order, the oxygen pressure in oxygen therapy passage 2A is equal to and setsDefinite value；
4), during oxygen conjunction, the blood inlet end blood oxygen concentration measuring instrument 5 at oxygen conjunction passage 2E blood inlet end and bleeding end, bleedingThe oxygen recording is closed the oxygen content in forward and backward blood and feeds back to controller 6 and be shown in control by end blood oxygen concentration measuring instrument 4 respectivelyPanel 7, medical personnel revise the setting value of oxygen pressure in oxygen therapy passage 2A accordingly.
Ultimate principle, principal character and the advantages of the present invention of the present invention have been shown and described above.The technology of the industryThe only present invention it should be appreciated that the present invention is not restricted to the described embodiments, described in above-described embodiment and description for the personnelPreference, be not intended to limit the present invention, without departing from the spirit and scope of the present invention, the present invention also has variousChanges and improvements, these changes and improvements both fall within scope of the claimed invention.Claimed scope is by instituteAttached claims and its equivalent thereof.