Clamping device and operation method thereof[ technical field ]
The invention relates to the technical field of medical equipment, in particular to a clamping device and an operation method thereof.
[ background Art ]
With the development of the technology of endoscopic treatment, many diseases of natural cavities of human bodies are usually treated by endoscopic surgery, wherein the treatment of mucosal lesion, defect and hemorrhage of the human bodies and perforation of the cavities is carried out by directly using a clamping device. The method is characterized in that a clamping device is firstly guided into a human body through an endoscope forceps channel, human tissues and blood vessels are clamped together by using mechanical compression force generated when the clamping part of the clamping device is closed, so that the tissues and the blood vessels are closed, the clamping part of the clamping device is retained on pathological tissues of the human body until the tissues heal, and the endoscope and the human body are withdrawn after the operation of conveying the operation part of the clamping device.
In the prior art, the following clamping devices are used to clamp tissues for wound closure and hemostasis:
in the patent document of chinese published patent application No. CN200980123274.7, a hemostatic clamping device and method are disclosed, which have no rotating mechanism, and cannot adjust the clamping angle relative to the tissue, resulting in poor clamping effect and even failure of clamping.
The inner part of the capsule body of the clamping device is many and long, so that the capsule body is long, and the long capsule body is retained by a human body and can stab human tissues opposite to the clamping part.
The clamping arms of the clamping device enter the bag body through deformation, plastic deformation is easy to generate, the opening becomes small after repeated opening and closing, and larger human tissues cannot be clamped.
In the patent document of chinese published patent application No. CN201180059362.2, a medical device with a detachable pivotable jaw is disclosed, the internal shape of the housing of the medical device is complex, four long grooves are provided on the outside as guiding surfaces of the caliper, the requirement of fitting precision is high, the processing and manufacturing of parts are difficult, the qualification rate is low, the cost is high, and the assembly with other parts is complex and difficult.
The caliper of the medical equipment is provided with a pinion and other structures, and has the advantages of difficult part processing and manufacturing, low qualification rate, high cost and complex and difficult assembly with other parts.
The driver of the medical equipment is provided with a rack and other structures, and has the advantages of difficult part processing and manufacturing, low qualification rate, high cost and complex and difficult assembly with other parts.
In the patent document of chinese published patent application No. CN201410222753.7, a hemostatic clip is disclosed, and a detachable connection structure is formed between a clip seat and a transition cap of the hemostatic clip through a buckle, and the structure is complex, difficult to assemble, and poor in connection reliability.
The transition cap and the fixation of the hemostatic clip form a rotary structure through the transition cap insert, and the rotary structure has a plurality of parts and is difficult to assemble and connect.
The clamping arm of the hemostatic clamp is provided with a chute matched with the fixed pin shaft, so that the structure of the part is complex, and the assembly is difficult.
The clamping arm and the tail hook structure of the hemostatic clamp are locked with the bulge of the clamp seat, the elastic plastic deformation of the clamping arm is realized by means of the back tension, the manufacturing tolerance range of three parts determines the required back tension and locking reliability, and the back tension can be too large or too small and can not be locked.
In the patent document of chinese published patent application No. CN201310272522.2, a clamping device and a clamping part thereof are disclosed, wherein a clamping piece of the clamping device enters a clamping tube through deformation, and is easy to generate plastic yielding deformation, and an opening of the clamping piece becomes small after repeated opening and closing, so that large human tissues cannot be clamped.
The clamping piece fixing seat and the unlocking piece of the clamping device are long in axial length, the clamping piece fixing seat and the unlocking piece are required to be installed in a long clamping pipe, the long clamping pipe is reserved for a human body, and human tissues opposite to the clamping part can be stabbed.
The clamping piece fixing seat and the unlocking piece of the clamping device are complex in shape and structure, the reed and other structures of the clamp pipe are complex to process, the cost of parts is high, and the product is difficult to assemble.
Therefore, a clamping device with a clamping part capable of being separated from other parts, more convenient in combined structure, large in clamping opening and short in retention length needs to be designed.
[ summary of the invention ]
The invention aims to solve the defects of the prior art, provides the clamping device which has the advantages of reasonable structure, simplicity, reliability, large clamping opening, short retention length, repeatable opening and closing, rotatability and the like, and also provides a simple and convenient operation method.
In order to achieve the above object, a clamping device is designed, comprising a clamping part (10) and a conveying operation part (20), characterized in that the clamping part (10) and the conveying operation part (20) can be separated;
the clamping part (10) comprises a clamping arm (11), a clamping tube (12), a spreading pin (13) and a connecting pin (14) and is used for clamping human tissues;
the proximal end of the clamping tube (12) is provided with a proximal end groove (12 a), a flange (12 c) and a counter bore (12 d), the distal end of the clamping tube (12) is provided with a distal end groove (12 b), an expanding piece (24) can be arranged in the counter bore (12 d) to elastically expand the flange (12 c), and the expanded flange (12 c) is detachably connected with a counter bore table (25 a) of the clamping seat (25);
the clamping arm is characterized in that the proximal end (11 a) of the clamping arm (11) is connected with the connecting pin (14), the middle section (11 b) of the clamping arm (11) is kept to move in the distal groove (12 b) of the clamping tube (12), the connecting pin (14) and the proximal end (11 a) and the middle section (11 b) of the clamping arm (11) are contained in the clamping tube (12), a pressing surface (12 f) is arranged at the proximal end of the distal groove (12 b) and used for blocking the clamping arm (11) from being opened continuously, a supporting pin (13) is arranged at the distal end of the clamping tube (12), and the supporting pin (13) is used for supporting and blocking the clamping arm (11) which moves forwards to the position.
The clamping arm (11) comprises a proximal end (11 a), a middle section (11 b) and a clamping section (11 c), wherein the proximal end (11 a) is provided with a connecting hole (11 d) and is connected with a connecting pin (14), the middle section (11 b) is kept in a distal groove (12 b) of the clamping tube (12), and the middle section (11 b) is provided with a pressure receiving surface (11 e) and a pressure applying surface (12 f) of the clamping tube (12) to form pressure contact, so that the clamping arm (11) is closed, and the clamping arm (11) is prevented from continuously moving backwards towards the proximal end.
The connecting pin (14) has flanges (14 c) and (14 d) at both ends for restricting the two clamping arms (11) from being spread apart.
The driving piece (21),
the far end of the connecting pin is provided with two hooks (21 c) which are connected with the connecting pin (14), and the hooks (21 c) can be deformed and straightened under preset tensile force so as to be separated from the connecting pin (14);
wherein the middle section is provided with two ribs (21 b), the two ribs (21 b) can move freely in a distal inner cavity (24 b) of the bulging piece (24), the two ribs (21 b) are limited in movement in a proximal inner ring (24 c) of the bulging piece (24), and the driving piece (21) can drive the bulging piece (24) to move backwards;
the proximal end (21 a) is inserted into the connecting tube (22) and fixedly connected.
The far end of the clamping seat (25) is provided with an inner ring (25 a), the inner ring (25 a) is detachably connected with a flange (12 c) of the clamping tube (12), and the near end (25 b) of the clamping seat (25) is fixedly connected with the far end (26 a) of the spring tube cap (26).
The connecting pin (14) cannot pass through the counter bore bottom (12 d) of the unexpanded clamping tube (12) so as to indirectly lock the clamping arm (11) against distal forward movement, and the connecting pin (14) can freely move in the expanded clamping tube (12) and the distal inner cavity (24 b) of the bulging piece (24).
The device is characterized in that a driving piece (21), a connecting pipe (22), a driving flexible shaft (23) and a clamp ring (32) of the conveying operation part (20) are sequentially and fixedly connected, a clamping seat (25), a spring pipe cap (26), a spring pipe (27) and a spring pipe seat (34) are sequentially and fixedly connected, a clamp handle (31) and a clamp handle insert (33) are fixedly connected, the clamp ring (32) is sleeved on the clamp handle (31), the clamp ring (32) and the clamp handle (31) can move axially relatively and cannot rotate, the spring pipe seat (34) is arranged between the clamp handle (31) and the clamp handle insert (33), and the spring pipe seat (34) can rotate relatively to the clamp handle (31) and the clamp handle insert (33) and cannot slide axially.
The invention also relates to a method for operating a clamping device, which is characterized in that the method comprises the following steps:
the clamp ring (32) is operated to be pulled backwards, so that the clamp ring (32), the driving flexible shaft (23), the connecting pipe (22), the driving piece (21), the connecting pin (14) and the clamping arm (11) can be sequentially pushed to move backwards, the pressure bearing surface (11 e) of the clamping arm (11) is pressed by the pressure bearing surface (12 f) of the clamping pipe (12), the clamping arm (11) is closed, and the clamping arm (11) is prevented from moving backwards towards the proximal end, namely, the clamping part (10) is closed to clamp human tissues;
when the clamp ring (32) is operated to pull back and the back pulling force reaches a set value, the two hooks (21 c) of the driving piece (21) can be subjected to plastic deformation and straightening, so that the two hooks can be separated from the connecting pin (14);
the two ribs (21 b) of the driving piece (21) can further pull the bulging piece (24) backwards, the bulging piece (24) is moved out from the counter bore (12 d) at the proximal end of the clamping tube (12), the flange (12 c) at the proximal end of the clamping tube (12) is not internally bulged and is reduced, the flange (12 c) can be moved out from the counter bore table (25 a) of the clamping seat (25), and the clamping part (10) is separated and released from the clamping seat (25) and the conveying operation part (20);
the bulging piece (24) is moved out from the counter bore (12 d) at the proximal end of the clamping tube (12), the counter bore (12 d) at the proximal end of the clamping tube (12) is not bulged but is reduced, the connecting pin (14) is locked by locking, the clamping arm (11) connected with the connecting pin (14) is prevented from moving forwards, and the clamping arm (11) is kept closed and locked.
Pushing forward the clamping arm (11), wherein a lower arm (11 g) of the clamping arm (11) is propped up by a propping up pin (13) and is blocked from continuing to move forward distally, and an upper arm (11 f) of the clamping arm (11) is blocked from continuing to open by a pressing surface (12 f) of the clamping tube (12);
the clamping arm (11) is pulled back, and the pressure bearing surface (11 e) of the clamping arm (11) is pressed by the pressure bearing surface (12 f) of the clamping tube (12), so that the clamping arm (11) is closed, and the clamping arm (11) is prevented from moving backwards towards the proximal end.
Compared with similar products in the market, when the specification of the clamping opening of the hemostatic clamping device of Boston science in the United states is 11mm, the retention length of the hemostatic clamping device is 15.5mm; when the clip opening size was 14mm, the retention length thereof was 17.9mm.
Medical devices with detachable pivotable jaws in kuke medicine in the united states have a residence length of 15mm when the clamping opening is 12mm in size; when the clip opening size was 14mm, the retention length thereof was 16.6mm.
When the specification of the clamping opening of the Nanjing minimally invasive hemostatic clamp is 16mm, the retention length of the hemostatic clamp is 13.8mm; when the clip opening size was 14mm, the retention length thereof was 12.2mm.
The retention length of the clamping device for Hangzhou Anrui medical treatment is 9.8mm when the specification of the clamping opening is 10 mm; when the clip opening size was 14mm, the retention length was 13mm.
Compared with the prior art, the clamping device and the method have the advantages that the clamping part can be separated from other parts conveniently, the combined structure is simple and feasible, the clamping opening is large, the detention length is short, when the specification of the clamping opening is 14mm, the detention length is only 11.5mm, the total length of the detention chuck is shortest, and in addition, the clamping device has a rotating function, the structure is simplest, and the cost is lowest.
[ description of the drawings ]
FIG. 1 is a schematic view of the overall structure of a clamping device according to the present invention;
FIG. 2 is a schematic top view of the clamping device of the present invention in an open state;
FIG. 3 is a schematic view of a clamping device of the present invention in a closed state;
FIG. 4 is a schematic top view of the clamping device of the present invention in a closed state;
FIG. 5 is a schematic view showing a released state of the clamping device according to the present invention;
FIG. 6 is a schematic top view of the released state of the clamping device of the present invention;
FIG. 7 is a schematic view of the connection of the clamping arms of the clamping device of the present invention;
FIG. 8 is a schematic view of the clamping tube and clamping seat of the clamping device of the present invention;
FIG. 9 is a schematic illustration of the connection of the spring tube, spring tube holder, clamp handle, etc. of the clamping device of the present invention;
FIG. 10 is a schematic view of a clamping arm of the clamping device of the present invention;
FIG. 11 is a schematic view of a clamping tube of the clamping device of the present invention;
FIG. 12 is a schematic view of a connecting pin of the clamping device of the present invention;
FIG. 13 is a schematic view of a driving member of the clamping device of the present invention;
FIG. 14 is a schematic view of an bulging member of the clamping apparatus of the present invention;
FIG. 15 is a schematic view of a clamping seat of the clamping device of the present invention;
FIG. 16 is a schematic view of a spring tube cap of the clamping device of the present invention;
in the figure: 10. clip portion 11, clip arm 11a, proximal end 11b, middle section 11c, clip section 11d, connecting bore 11e, pressure receiving surface 11f, upper arm 11g, lower arm 12, clip tube 12a, proximal slot 12b, distal slot 12c, flange 12d, counterbore 12e, pin bore 12f, pressure receiving surface 13, bracing pin 14a, connecting pin piece 14b, connecting pin piece 14c, flange 14d, flange 20, delivery handle 21, driver proximal end 21b, ribs 21c, hook 22, connecting tube 23, drive hose 24, expander 24a, outer portion 24b, distal cavity 24c, proximal inner ring 25, clip 25a, clip proximal end 26, spring cap 26a, outer rim 26b, spring cap proximal end 26c, cavity 27, spring tube 31, clamp handle 32, clamp ring 33, clamp handle insert 34, spring tube holder.
Detailed description of the preferred embodiments
The construction and principles of such apparatus and methods will be apparent to those skilled in the art from the following description of the invention taken in conjunction with the accompanying drawings. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
Example 1
A gripping device as shown in fig. 1 and 2, comprising a gripping part (10) and a transport handling part (20), both being separable;
the clamping part (10) comprises a clamping arm (11), a clamping tube (12), a spreading pin (13) and a connecting pin (14) and is used for clamping human tissues, and the human tissues are automatically fallen off or removed after being retained for a period of time;
the clamping arm (11) comprises a connecting pin (14), a connecting pin (14) and a pressing surface (12 f) of the clamping arm (12), wherein the proximal end (11 a) of the clamping arm (11) is connected with the connecting pin (14), a middle section (11 b) of the clamping arm (11) is kept to move in a distal groove (12 b) of a clamping tube (12), the clamping tube (12) is used for accommodating the connecting pin (14) and the proximal end (11 a) and the middle section (11 b) of the clamping arm (11), the pressing surface (12 f) of the clamping tube (12) is used for blocking the opened clamping arm (11) from being opened continuously, and a supporting pin (13) is arranged at the distal end of the clamping tube (12) and is used for supporting and blocking the clamping arm (11) which moves forwards to the position;
the conveying operation part (20) comprises a driving piece (21), a connecting pipe (22), a driving flexible shaft (23), a bulging piece (24), a clamping seat (25), a spring pipe cap (26), a spring pipe (27), a clamp handle (31), a clamp ring (32), a clamp handle insert (33) and a spring pipe seat (34), and is used for pushing the clamping part (10) into an endoscope cavity and a human body and operating the clamping part (10) to work;
the device comprises a driving piece (21), a connecting pipe (22), a driving flexible shaft (23) and a sequentially fixed connection, wherein a clamping seat (25), a spring pipe cap (26), a spring pipe (27) and a spring pipe seat (34) are sequentially and fixedly connected, a clamp handle (31) is fixedly connected with a clamp handle insert (33), a clamp ring (32) is sleeved on the clamp handle (31), the clamp ring (32) and the clamp handle (31) can move axially relatively and cannot rotate, the spring pipe seat (34) is arranged between the clamp handle (31) and the clamp handle insert (33), and the spring pipe seat (34) can rotate relatively to the clamp handle (31) and the clamp handle insert (33) and cannot slide axially;
the proximal end of the clamping tube (12) is provided with a proximal end groove (12 a), a flange (12 c) and a counter bore (12 d), the distal end of the clamping tube (12) is provided with a distal end groove (12 b), an expansion piece (24) can be arranged in the counter bore (12 d) to elastically expand the flange (12 c), and the expanded flange (12 c) is detachably connected with a counter bore table (25 a) of the clamping seat (25);
the operating clamp ring (32) can push the clamp ring (32), the driving flexible shaft (23), the connecting pipe (22), the driving piece (21), the connecting pin (14) and the clamping arm (11) forward in sequence, and the clamping arm (11) is propped by the propping pin (13), namely the clamping part (10) is opened, so that human tissues can be clamped subsequently;
the operating clamp handle (31) can sequentially drive the clamp ring (32), the driving flexible shaft (23), the connecting pipe (22), the driving piece (21) and the clamping part (10) to rotate relative to the clamping seat (25).
As shown in fig. 3 and 4, the clamp ring (32) is operated to push the clamp ring (32), the driving flexible shaft (23), the connecting pipe (22), the driving piece (21), the connecting pin (14) and the clamping arm (11) backward in sequence, the pressure bearing surface (11 e) of the clamping arm (11) is pressed by the pressure bearing surface (12 f) of the clamping pipe (12), so that the clamping arm (11) is closed, and the clamping arm (11) is prevented from moving backward towards the proximal end, namely, the clamping part (10) is closed to clamp human tissues.
In a clamping device as shown in fig. 5 and 6, when the clamp ring (32) is operated to pull back and the back pulling force reaches a set value, the two hooks (21 c) of the driving member (21) can be deformed and straightened, so that the two hooks can be separated from the connecting pin (14);
the two ribs (21 b) of the driving piece (21) can further pull the bulging piece (24) backwards, the bulging piece (24) is moved out of the counter bore (12 d) at the proximal end of the clamping tube (12), the flange (12 c) at the proximal end of the clamping tube (12) is not internally bulged and is reduced, the flange (12 c) can be moved out of the counter bore table (25 a) of the clamping seat (25), and the clamping part (10) is separated and released from the clamping seat (25) and the conveying operation part (20).
The bulging piece (24) is moved out from the counter bore (12 d) at the proximal end of the clamping tube (12), the counter bore (12 d) at the proximal end of the clamping tube (12) is not bulged but is contracted, the connecting pin (14) is locked, the clamping arm (11) connected with the connecting pin (14) is prevented from moving forwards, and the clamping arm (11) is kept closed and locked.
As shown in fig. 7, the connecting holes (11 d) at the distal ends of the two holding arms (11) are connected with the connecting pin (14), the two hooks (21 c) at the distal ends of the driving member (21) are movably connected with the connecting pin (14), and the proximal end (21 a) of the driving member is inserted into the connecting pipe (22) and fixedly connected.
As shown in fig. 8, the proximal end of the clamping tube (12) is provided with a proximal groove (12 a), a flange (12 c) and a counter bore (12 d), wherein a bulging piece (24) can be arranged in the counter bore (12 d) to elastically bulge the flange (12 c), and the outer diameter of the bulged flange (12 c) is larger than the inner diameter of a counter bore table (25 a) of the clamping seat (25);
the two ribs (21 b) of the driving piece (21) pull the bulging piece (24) backwards, the bulging piece (24) is completely removed from the counter bore (12 d) of the clamping tube (12), the flange (12 c) of the clamping tube (12) which is not expanded is elastically retracted, the outer diameter of the flange (12 c) is smaller than the inner diameter of the counter bore table (25 a) of the clamping seat (25), and the clamping tube (12) can be removed from the clamping seat (25); the clamping tube (12) and the clamping seat (25) form a detachable connection.
As shown in fig. 9, the spring tube (27) is fixedly connected with the spring tube seat (34), and the clamp handle (31) is fixedly connected with the clamp handle insert (33); the spring tube seat (34) is assembled in a gap between the clamp handle (31) and the clamp handle insert (33), a small amount of clearance exists in the axial direction, and a sufficient amount of clearance exists in the circumferential direction; a proximal jaw shank insert (33) of the spring tube (27) has a sufficient amount of clearance circumferentially therein; the grip (31) and grip insert (33) are rotatable relative to the spring tube (27) and the spring tube holder (34).
The clamp handle (31) is circumferentially fixed with the clamp ring (32), the clamp ring (32) is fixedly connected with the driving flexible shaft (23), and the rotating clamp handle (31) can sequentially drive the clamp ring (32), the driving flexible shaft (23), the connecting pipe (22), the driving piece (21) and the clamping part (10) to rotate relative to the spring tube seat (34), the spring tube (27), the spring tube cap (26) and the clamping seat (25).
As shown in fig. 10, the clamping arm (11) comprises a proximal end (11 a), a middle section (11 b) and a clamping section (11 c), wherein the proximal end (11 a) is provided with a connecting hole (11 d) to be connected with a connecting pin (14), the middle section (11 b) is kept in a distal end groove (12 b) of the clamping tube (12),
the middle section (11 b) is provided with a pressure surface (11 e) which can form pressure contact with a pressure surface (12 f) of the clamping tube (12) so as to close the clamping arm (11) and prevent the clamping arm (11) from continuously moving backwards proximally,
the clamping arm (11) is pushed forward, the lower arm (11 g) of the clamping arm (11) is propped up by the propping up pin (13) and blocked from continuing to move forward distally, the upper arm (11 f) of the clamping arm (11) is blocked from continuing to open by the pressing surface (12 f) of the clamping tube (12),
the clamping arm (11) is pulled back, and the pressure bearing surface (11 e) of the clamping arm (11) is pressed by the pressure bearing surface (12 f) of the clamping tube (12), so that the clamping arm (11) is closed, and the clamping arm (11) is prevented from moving backwards towards the proximal end.
As shown in fig. 11, the proximal end of the clamping tube (12) is provided with a proximal groove (12 a), a flange (12 c) and a counter bore (12 d), the counter bore (12 d) can be internally provided with a bulging piece (24) for elastically bulging the flange (12 c), the bulged flange (12 c) is detachably connected with a counter bore table (25 a) of the clamping seat (25), the distal end of the clamping tube (12) is provided with a distal groove (12 b), and the middle section (11 b) of the clamping arm (11) is kept sliding in the distal groove (12 b). The pressing surface (12 f) of the clamping tube (12) can press the upper arm (11 f) of the opened clamping arm (11) to prevent the clamping arm (11) from being opened continuously, and the pressing surface (12 f) of the clamping tube (12) can press the pressed surface (11 e) of the opened clamping arm (11) to close the clamping arm (11) and prevent the clamping arm (11) from being moved backwards continuously.
As shown in fig. 12, the connecting pin (14) has flanges (14 c) and (14 d) at both ends for restricting the two holding arms (11) from being spread, and the connecting pin (14) may be composed of two parts (14 a) and (14 b) for the convenience of manufacturing.
As shown in fig. 13, the driving member (21) is provided with two hooks (21 c) at its distal end and connected with the connecting pin (14), the hooks (21 c) can be deformed and straightened under a predetermined tensile force, so as to be separated from the connecting pin (14), the middle section is provided with two ribs (21 b), the two ribs (21 b) can move freely in the distal end inner cavity (24 b) of the bulging member (24), the two ribs (21 b) are limited in movement in the proximal end inner ring (24 c) of the bulging member (24), the driving member (21) can drive the bulging member (24) to move backwards, and the proximal end (21 a) of the driving member is inserted into the connecting tube (22) and fixedly connected. The hook (21 c) of the drive element (21) may also be a hook with a larger angle.
As shown in fig. 14, the outer portion (24 a) of the bulging piece (24) is inserted into the counter bore (12 d) of the proximal end of the holding pipe (12) to bulge the flange (12 c) of the proximal end of the holding pipe (12); the distal end inner cavity (24 b) of the bulging piece (24) can accommodate the free movement of the two ribs (21 b) of the driving piece (21), the two ribs (21 b) of the driving piece (21) cannot penetrate through the proximal end inner ring (24 c) of the bulging piece (24), and the driving piece (21) can drive the bulging piece (24) to move backwards.
As shown in fig. 15, the distal end of the holder (25) has an inner ring (25 a), the inner ring (25 a) is detachably connected to the flange (12 c) of the holding tube (12), and the proximal end (25 b) of the holder (25) is fixedly connected to the distal end (26 a) of the spring tube cap (26).
As shown in fig. 16, the outer edge (26 a) of the spring tube cap (26) is fixedly connected with the proximal end (25 b) of the holder (25), the proximal end (26 b) of the spring tube cap (26) is fixedly connected with the distal end of the spring tube (27), and the inner cavity (26 c) of the spring tube cap (26) accommodates the rearward-moving bulging piece (24).
It is emphasized that: the above embodiments are merely preferred embodiments of the present invention, and the present invention is not limited in any way, and any simple modification, equivalent variation and modification made to the above embodiments according to the technical substance of the present invention still fall within the scope of the technical solution of the present invention.