Implanted vagus nerve dual pathways stimulating apparatusTechnical field
The present invention relates to armarium technology, particularly relate to the skill of a kind of implanted vagus nerve dual pathways stimulating apparatusArt.
Background technology
Implanted vns device is to stimulate vagal armarium by output electrical stimulation signal.ExistingSome implanted vns device are mainly different by electric stimulation pulse generator, wound form location anchor and two polarityWound form electrode forms, and wound form positions during use anchor and two wound form electrodes are wrapped on target vagus nerve, is wound aroundFormula location anchor is for two the wound form electrodes in location, and electric stimulation pulse generator is used for exporting electrical stimulation signal and controls two and twineWound electrode works, thus realizes stimulation vagal to target.
Existing implanted vns device all only has two wound form electrodes, can only be to one side in the same timeVagus nerve stimulates, and its field stimulation is narrower, and effect of stimulation is the most poor, and existing implanted vns deviceUse open stimulus modelity, not for the monitoring of vital sign parameter, there is potential stimulation risk, thus giveBy nerve electric stimulation, person brings potential safety hazard.Potential safety hazard, existing implanted fan is there is just because of open stimulus modelityWhen walking nerve stimulation device use, within the same time, all only unilateral vagus nerve is carried out nerve electric stimulation, the most onlyIt is equipped with two wound form electrodes.
Further, in existing implanted vns device, wound form location anchor and two wound form electrodes be according toThe sequencing arrangement of operation technique, i.e. two wound form electrodes are all laid in the same side of wound form location anchor, in operationDuring operation, doctor positions anchor, proximal wind formula electrode (i.e. proximal wind formula electricity close to the anchor of wound form location according to wound formPole), wound form positions the order of far-end wound form electrode anchor and two wound form electrodes are sequentially wrapped in target vagus nerveOn, but when being wound around proximal wind formula electrode, far-end wound form electrode is also in free state, and due to far-end wound formFarther out, travelling amplitude also can be relatively large for electrode distance wound form location anchor, easily interference doctor operation, thus adds doctorOperation easier.
Summary of the invention
For defect present in above-mentioned prior art, the technical problem to be solved is to provide and a kind of stimulates effectThe best, safety is high, and the implanted vagus nerve dual pathways stimulating apparatus that operation easier is low.
In order to solve above-mentioned technical problem, a kind of implanted vagus nerve dual pathways stimulating apparatus provided by the present invention,Including implanting unit, electric stimulation pulse generator, it is characterised in that: this device also includes for detecting the heart rate of human body, breathingThe sign detection module of the sign situation such as frequency, blood oxygen saturation；Described sign detection module is with radio communication or wire communicationMode connects electric stimulation pulse generator；
Described implantation unit includes wound form location anchor, flexible electrode big envelope, and the wound form electrode that two polarity is different, itsIn wound form location anchor be fixed on electrode big envelope by the cross structure of a flexibility, two wound form electrodes are placed in wound formThe both sides of location anchor, the electrical lead wire of two wound form electrodes is each passed through electrode big envelope affixed with electrode big envelope；
Described implantation unit has two, and one of them implants unit is the first implantation unit, and another implants unit is secondImplant unit；
Described electric stimulation pulse generator is provided with for exporting the first boost pulse output port of electric stimulation pulse, the second stimulationPulse output end mouth, the first electrical lead wire implanting two wound form electrodes in unit receives the of electric stimulation pulse generatorOne boost pulse output port, the second electrical lead wire implanting two wound form electrodes in unit is received electric stimulation pulse and is occurredSecond boost pulse output port of device.
Further, also include for electric stimulation pulse generator input control signal manually stimulate control module,Control module is manually stimulated to connect electric stimulation pulse generator with radio communication or wire communication mode.
Further, described wound form electrode is by spiral base load circle, and the electrode strip composition being fixed on base load circle,Base load circle has elasticity and flexibility, and the two ends of base load circle are all fixed with the boost line of flexibility.
Further, described wound form location anchor is the spiral type anchor with elasticity and flexibility, the two of wound form location anchorEnd is all fixed with the boost line of flexibility.
The implanted vagus nerve dual pathways stimulating apparatus that the present invention provides, uses closed type stimulus modelity, is implementing electricityIn stimulating course, it is possible to use sign detection module detects human body physical sign situation in real time, thus reduces stimulation risk, has peaceThe feature of Quan Xinggao, the most therefore can utilize two to implant unit and both sides vagus nerve be implemented electricity irritation simultaneously, improve thornSwashing effect, and implanting in unit, two wound form electrodes are placed in the both sides of wound form location anchor, two wound form electrodesWith distance all relative close of wound form location anchor, travelling amplitude is the most relatively small, and the impact on doctor's operation is the least, thusReduce the operation easier of doctor.
Accompanying drawing explanation
Fig. 1 is the structural representation of the implanted vagus nerve dual pathways stimulating apparatus of the embodiment of the present invention.
Detailed description of the invention
Illustrate embodiments of the invention are described in further detail below in conjunction with accompanying drawing, but the present embodiment is not used to limitThe present invention processed, the analog structure of every employing present invention and similar change thereof, protection scope of the present invention, the present invention all should be listed inIn pause mark all represent the relation of sum.
As it is shown in figure 1, a kind of implanted vagus nerve dual pathways stimulating apparatus that the embodiment of the present invention is provided, including plantingEnter unit, electric stimulation pulse generator U1, it is characterised in that: this device also include for detect the heart rate of human body, respiratory frequency,The sign detection module U2 of the sign situations such as blood oxygen saturation；Described sign detection module U2 is with radio communication or wire communication sideFormula connects electric stimulation pulse generator U1；
Described implantation unit includes wound form location anchor M1, flexible electrode big envelope T1, and the wound form electricity that two polarity is differentPole J1, J2, wound form therein location anchor M1 is fixed on electrode big envelope T1 by the cross structure B1 of a flexibility, two wound formsElectrode J1, J2 be placed in wound form location anchor M1 both sides, the electrical lead wire of two wound forms electrode J1, J2 is each passed through electrodeBig envelope T1 is the most affixed with electrode big envelope；
Described implantation unit has two, and one of them implants unit is the first implantation unit, and another implants unit is secondImplant unit；
Described electric stimulation pulse generator U1 is provided with for exporting the first boost pulse output port of electric stimulation pulse, the second thornSwashing pulse output end mouth, the first electrical lead wire implanting two wound forms electrode J1, J2 in unit is received electric stimulation pulse and is sent outThe first boost pulse output port of raw device U1, the second electrical lead wire implanting two wound forms electrode J1, J2 in unit connectsThe second boost pulse output port to electric stimulation pulse generator U1.
The embodiment of the present invention also include for electric stimulation pulse generator U1 input control signal manually stimulate controlModule U3, manually stimulates control module U3 to connect electric stimulation pulse generator U1 with radio communication or wire communication mode.
In the embodiment of the present invention, described wound form electrode is by spiral base load circle, and is fixed on the electrode on base load circleBar forms, and base load circle has elasticity and flexibility, and the spiral internal diameter of base load circle is 1.5～1.8mm, and the coil number of base load circle is 2.5Individual circumference, the length of run of base load circle is 18～25mm, and the two ends of base load circle are all fixed with the boost line of flexibility, and boost line is canImplant surgery silk thread, the line length of boost line is 8～10mm, can help to winding operation in operation；Electrode strip is width 1mm'sMetal silver strip, the outer surface platinum plating of electrode strip, electrode strip is embedded in the middle part of the medial surface of base load circle in the partly mode of burying.
In the embodiment of the present invention, described wound form location anchor is the spiral type anchor with elasticity and flexibility, and wound form positionsThe spiral internal diameter of anchor is 1.5～1.8mm, and the coil number of wound form location anchor is 3 circumference, the length of run of wound form location anchorBeing 24～30mm, the two ends of wound form location anchor are all fixed with the boost line of flexibility, and boost line is implantable operation silk thread, auxiliaryThe line length of index contour is 8～10mm, can help to winding operation in operation.
In the embodiment of the present invention, the external diameter of described electrode big envelope is 2.7～3mm, a length of the 5 of cross structure～7mm, connectsThe width of bridge is 2.9～3.1mm, and the electrical lead wire of wound form electrode can be played a protective role by electrode big envelope, and electrodeBig envelope is connected by cross structure with wound form location anchor, positions coordinating of anchor by electrode big envelope with wound form, can be to windingFormula electrode plays positioning action.
In the embodiment of the present invention, described electric stimulation pulse generator, sign detection module, manually stimulation control module arePrior art.
The stimulating method of the implanted vagus nerve dual pathways stimulating apparatus that the embodiment of the present invention is provided is as follows:
Two wound forms implanted in unit position anchor, wound form electrode implantation within a patient respectively, and each implantation unit existsWhen implanting wound form location anchor, wound form electrode, first wound form is positioned anchor and is wrapped on target vagus nerve, the most again by twoIndividual wound form electrode is successively wrapped on target vagus nerve, and electric stimulation pulse generator is detected in real time by sign detection moduleThe sign situation of patient；
If the sign condition monitor data that electric stimulation pulse generator receives is in safety range set in advance, electricity irritation arteries and veinsRush generator and i.e. control rule output electric stimulation pulse according to set in advance stimulation so that two wound forms implanted in unitElectrode carries out electricity irritation according to corresponding stimulation rules to the target vagus nerve of patient；
If the sign condition monitor data that electric stimulation pulse generator receives exceeds in safety range set in advance, electricity irritationPulse generator, i.e. according to security control set in advance rule, stops output side or bilateral electric stimulation pulse or to electricity irritationThe stimulus parameter of pulse is adjusted, and the stimulus parameter of electric stimulation pulse includes electricity irritation pulsewidth, electricity irritation duration, electricity irritation frequencyThe exchange of rate, electricity irritation single-phase two-phase, stimulating current intensity etc.；
Doctor can manually stimulate control module to input corresponding manual control signal to electric stimulation pulse generator, thusImplement electric stimulation pulse generator manually to intervene.