Heart volume reduction systemTechnical field
The present invention relates to medical field, particularly relate to a kind of therapeutic medical heart volume reduction system.
Background technology
Heart failure has become the healthy heavy burden in the whole world, and whole world heart failure patient there are about 26,000,000 at present, and prevalence is1-2%.More than 70 years old crowd's heart failure prevalence >=10% of American-European countries.In the heart failure patient course of disease of 74% at least oneComplication, this type of patient is easier to occur the deterioration of disease, causes admission rate and mortality rate to remain high again.Advanced heart failure prognosisMore worse than part entity tumor and myocardial infarction, 5 annual survival rates of severe patient are less than 20%.Heart failure brings for society simultaneouslyHuge financial burden.
In recent years, being paid attention to by clinic more and more, it main reason is that it becomes whole world morbidity and dead headWant one of inducement, even and if calcification score technology development widely available instantly, still have 20%～50% myocardial infarction patientCan transfer heart failure patient to, and left ventricle geometry is as one of the main prognosis of heart failure, particularly myocardial ischemiaHeart geometry can be changed.Three coronary artery are easiest to myocardial infarction occur with anterior descending branch especially, the antetheca that result causes, there is apex impaired movement even ventricular aneurysm in large area infarction, increases the weight of remodeling ventricle further and CHF occursSymptom.After acute anterior wall myocardial infarction patients, myocardial necrosis and scarring subsequently, cause left ventricular remodeling, causes left ventricle dilation and a left sideVentricular systolic function declines.The important symbol of remodeling ventricle is exactly wall tension change and heart volume change.Therefore machineryThe minimizing bulk of left ventricle of property can alleviate wall tension thus improve remodeling ventricle, here it is the theory of surgery partial left ventriculectomy depends onAccording to.Though the history in partial left ventriculectomy existing more than 50 years, surgery operating wound is relatively big, and to the requirement of surgery patient relativelyHeight makes clinical practice limited.
Summary of the invention
For overcoming disadvantages mentioned above, it is an object of the invention to provide and a kind of heart failure can be carried out the medical of insertion type treatmentHeart volume reduction system.
In order to reach object above, the technical solution used in the present invention is: a kind of heart volume reduction system, fills including volume reductionPutting, described capacity-reduction device includes that multi-rod skeleton, described multi-rod skeleton are made up of multiple brace rods, brace rod described in each twoBetween have fixed angle, each described brace rod top to be formed with barb, turn up formation peviform along surrounding in described brace rod top,Described brace rod surface is covered with macromolecule isolating membrane, and described multi-rod skeleton can shrink, and fixes one bottom described multi-rod skeletonIndividual support pedestal, described heart volume reduction system also include metallic rod that guidance system, described guidance system include being wholely set andProtection set, described protection set uses macromolecular material, and described protection set is set in the outside of metallic rod, and described metallic rod can protectedSlidably reciprocating in sheath, the top of described metallic rod is connected with supporting pedestal, and described support pedestal uses thermoplastic polyurethane bulletElastomer material, it is internal that described metallic rod can drive support pedestal and multi-rod skeleton to slide to protection set.
Heart volume reduction system of the present invention provides the benefit that, barb plays fixation at cardiac muscle, prevents the dress after releasePut and be moved, stability and the intensity of heart volume reduction system can be effectively improved；Guidance system uses macromolecular material or goldBelong to material, there is preferable propelling movement ability.Heart volume reduction system can be by puncturing mode, specifically by volume reduction being filledPut and be housed in guidance system, penetrate on left ventricle surface and heart volume reduction system is delivered in human heart, be implanted in heartIn, capacity-reduction device operates by guidance system, sliding opening capacity-reduction device, by use multi-rod skeleton and isolating membraneCompartmentation, effectively reduces ventricular volume, reduces ventricle tension force, improves the cardiac function of remodeling ventricle and patient.Overcome existingThe elastic performance of wadding is poor, cardiac stimulus inner chamber；And the shortcoming that existing wadding structure stimulates the apex of the heart etc..Heart volume reduction systemSystem fix and fit in heart by surface barb in heart inner cavity position, particularly cardiac lumen owing to disease is in irregularlyShape, is prevented effectively from cardiac stimulus inner chamber, and the fixing pedestal that supports uses Thermoplastic polyurethane elastomer material simultaneously, can protect the heartPoint is not damaged, and utilizes the separation of isolating membrane, stops blood to flow into the apex of the heart, plays plugging action.Many by capacity-reduction deviceRod-type skeleton from swollen at cardiac lumen, effectively reduce ventricular volume, and reduces ventricle tension force, to reach to improve remodeling ventricle and troubleThe therapeutic purposes of the cardiac function of person；The metallic rod of guidance system and protection set unitary design, conveniently operate and exit heart.
Preferably, described multi-rod skeleton is by can making from swollen Nitinol.Niti material has Memorability and superlasticProperty characteristic, be effectively improved the size restoration of bracing frame and overall compliance, more effectively avoid cardiac stimulus inner chamber.
Preferably, a diameter of the 60～120mm of capacity-reduction device；Can effectively cover most patient demand.
Preferably, the quantity of described brace rod is 12-25, and fixed angle between brace rod described in each two be 15 °-30°。
Preferably, described macromolecule isolating membrane is electricity textile polymer.This material has good biocompatibility, controlsBiological interaction and specialty filtering medium, and without or less fluid seepage performance, play the effect effectively blocked and isolate.
Preferably, described support pedestal and the type of attachment of capacity-reduction device be hot jet welding or UV optical cement bonding.Improve the heartThe stability that dirty volume reduction system is overall.
Preferably, described brace rod top turns up 40 °-50 ° along surrounding.
Preferably, a length of 1.5-3mm of described barb.
Preferably, described multi-rod skeleton and macromolecule isolating membrane use suture way combination fixing.This mode can makeIsolating membrane is effectively fixed on multi-rod skeleton and improves the support force of multi-rod skeleton.
Preferably, described support pedestal is formed in one with multi-rod skeleton.Seamless compartmentation can be played, improve heartThe structural stability that volume reduction system is overall, without dropping risk.
Accompanying drawing explanation
Fig. 1 is the structural representation after the release of heart volume reduction system；
Fig. 2 is heart volume reduction system top view；
Fig. 3 is the top view after the release of multi-rod skeleton；
Fig. 4 is the structural representation before guidance system release；
Fig. 5 is the structural representation after guidance system exits heart.
In figure:
1-capacity-reduction device；2-guidance system；3-brace rod；4-isolating membrane；5-supports pedestal；6-barb；7-multi-rod boneFrame；8-metallic rod；9-protects set.
Detailed description of the invention
Below in conjunction with the accompanying drawings presently preferred embodiments of the present invention is described in detail, so that advantages and features of the invention energyIt is easier to be readily appreciated by one skilled in the art, thus protection scope of the present invention is made apparent clear and definite defining.
Seeing shown in accompanying drawing 1-5, a kind of heart volume reduction system in the present embodiment, including capacity-reduction device 1, capacity-reduction device 1Including multi-rod skeleton 7, multi-rod skeleton 7 uses can be from swollen nickel-titanium alloy material, and multi-rod skeleton 7 is by multiple brace rods 3Constitute, brace rod 3 quantity be the fixed angle between 12-25, and each two brace rod 3 be 15 °-30 °, each brace rod 3 pushes upPortion is formed with the barb 6 of a length of 1.5-3mm, turns up formation peviform along surrounding in brace rod 3 top, formed a diameter of 60～120mm, brace rod 3 top turns up 40 °-50 ° along surrounding, and brace rod 3 surface is covered with macromolecule isolating membrane 4, multi-rod skeleton 7 energyShrinking, fix one and support pedestal 5 bottom multi-rod skeleton 7, heart volume reduction system also includes that guidance system 2, guidance system 2 wrapIncluding the metallic rod 8 being wholely set and protection set 9, protection set 9 use macromolecular material, protection set 9 is set in outside metallic rod 8Portion, metallic rod 8 can slidably reciprocate in protection set 9, and the top of metallic rod 8 is connected with supporting pedestal 5, supports pedestal 5 and uses heatPlastic polyurethane elastomeric material, it is internal that metallic rod 8 can drive support pedestal 5 and multi-rod skeleton 7 to slide to protection set 9.
Macromolecule isolating membrane 4 is electricity textile polymer.
Support pedestal 5 and the type of attachment of capacity-reduction device 1 be hot jet welding or UV optical cement bonding.
Multi-rod skeleton 7 and macromolecule isolating membrane 4 use suture way combination fixing.
The fixing pedestal 5 that supports is formed in one with multi-rod skeleton 7.
Embodiment of above only for technology design and the feature of the present invention are described, its object is to allow and is familiar with techniquePeople understands present disclosure and is carried out, and can not limit the scope of the invention with this, all according to present invention spiritThe equivalence that essence is done changes or modifies, and all should contain within the scope of the present invention.