A kind of reaction cup storehouse and full-automatic illumination immunity analysis instrumentTechnical field
The present invention relates to technical field of medical equipment, specifically a kind of reaction cup storehouse and full-automatic illumination immunoassayInstrument.
Background technology
The supporting reagent of full-automatic illumination immunity analysis instrument is enzyme-catalyzed chemical luminescence method reagent, is referred to known antibodies bagSample to be tested and ELIAS secondary antibody in micropore reaction cup, are added, carries out immune response, is eventually adding substrate, produces aura,It is detected a kind of technology of instrument capture.Full-automatic illumination immunity analysis instrument is used to analyze in serum, blood plasma and other people body body fluidAnalyte, quantitative patients serum and horseradish peroxidase are added into solid-phase coating has in the micropore cup of antibody, in serumTesting molecule combined with the antibody specificity on the conjugate and solid phase carrier of horseradish peroxidase.Separating, washing unreactedFree composition.Then, luminol Luminol luminous substrates are added, centre is excited using the free energy of chemical reaction releaseBody, excitation state is returned to from ground state, energy is discharged in the form of photon, now, the photon of each micropore cup is read by photon counterCount, the mathematical modeling that the testing molecule concentration in sample is established according to standard items carries out quantitative analysis.
In the detection process for carrying out the above, it is typically necessary and uses reaction cup, sample and reagent are added into reaction cupInside to be reacted, reaction cup is disposable, therefore full-automatic illumination immunity analysis instrument needs to dispose a fairly large number of reaction cup,And need that reaction cup continuously is delivered into reaction tray, existing single reaction cup storage and conveying are not very square in the marketJust, it is necessary to be transported to question response area again after the reaction cup of placement region is first captured, it is easy to lose in this operating processMiss, and then influence detection below.
The content of the invention
The present invention provides a kind of simple in construction, reaction cup storage and more convenient, the safe and reliable reaction cup storehouse of conveyingAnd full-automatic illumination immunity analysis instrument.
The present invention is achieved through the following technical solutions：
A kind of reaction cup storehouse, including shell, Double Tops lever apparatus, the first bottom plate, the first fixing axle, the first motor, reaction cupPipe, reaction cup, reaction top rotary table and reaction lower rotary table, the shell by the first fixing axle, the first motor, reaction cup pipe, reactionCup, reaction top rotary table and reaction lower rotary table are wrapped in inside, and the lower end of first fixing axle is fixed on first bottom plate,The reaction top rotary table and reaction lower rotary table are set with the top and bottom of first fixing axle, and in the first motor andRotated under the drive of first pulley device around the first fixing axle, the reaction cup superposition is inside reaction cup pipe, the reactionThe top and bottom of cup pipe are installed on reaction top rotary table and reaction lower rotary table respectively, and the Double Tops lever apparatus passes through support meanssIt is fixed on first bottom plate, Double Tops lever apparatus is located at directly over reaction cup pipe above the reaction top rotary table.
The Double Tops lever apparatus include two double-pole motors, two screw mandrels, Double Tops rod bearing, two Double Tops rod guides andTwo pieces of double-pole sliding blocks, the support meanss include support and supporting plate, and the support is fixed on described first by supporting plateOn bottom plate, the Double Tops rod bearing and double-pole motor, which are parallel to each other, to be fixed on the rack upper surface, and two double-poles are ledRail it is vertical and it is parallel be fixed on Double Tops rod bearing, two pieces of double-pole sliding blocks are slidably connected with two Double Tops rod guides respectively,The upper end of two double-pole motor output ends is connected with two pieces of double-pole sliding blocks respectively.
The Double Tops rod bearing is upper to be provided with a yardstick vertically in the side of Double Tops rod guide, on the double-pole sliding blockIt is provided with positioned at the yardstick side and pushes away a glass sensor, glass sensor that pushes away follows double-pole sliding block to move up and down, and passes through codeChi is counted.
The reaction cup pipe includes two cavitys being parallel to each other, and reaction cup superposition is put into two cavitys, reaction cup pipeLower end be provided with shell fragment around two cavitys.
The neighboring of the reaction top rotary table is provided with a circle reaction cup pipe clamp groove, is provided with each reaction cup pipe clamp groove anti-Pipe clamping pieces are answered, the reaction lower rotary table is provided with the circle through hole corresponding with the reaction cup pipe clamp groove, the number of the through holeMeasure as twice of reaction cup pipe clamp groove, for a reaction cup pipe clamp groove, the upper end of reaction cup pipe is caught in described anti-two through holesAnswer in pipe clamping pieces, lower end is inserted in two through holes.
The reaction top rotary table is provided with sensing and cut into slices, and the supporting plate is provided with reaction cup storehouse motion sensor, describedSensing section and reaction cup storehouse motion sensor are located on same circumference.
The reaction cup storehouse also includes scanner, and scanner window is provided with shell.
The first fixing axle outer cover is provided with the first axle sleeve, and two are provided between first axle sleeve and the first fixing axleClutch shaft bearing, the first pulley device include the first big belt wheel, the first small pulley and the first belt, and first small pulley is consolidatedDue in the output end of first motor, first big belt wheel is installed on the lower end of first axle sleeve, passes through the first skinFirst big belt wheel is connected by band with the first small pulley.
Some light barriers are provided between the reaction top rotary table and reaction lower rotary table.
A kind of full-automatic illumination immunity analysis instrument, including above-described reaction cup storehouse.
Beneficial effect is caused by the present invention：
In the present invention, the reaction cup storehouse includes shell, Double Tops lever apparatus, the first bottom plate, the first fixing axle, the first electricityMachine, reaction cup pipe, reaction cup, reaction top rotary table and reaction lower rotary table, reaction cup superposing type are put into reaction cup pipe, pass through Double TopsLever apparatus ejects reaction cup from reaction cup pipe bottom one by one, just falls after ejection in reaction tray.Reaction cup storehouse isRotate, after the reaction cup in a reaction cup pipe has all used, it is only necessary to revolving reaction top rotary table and reaction lower rotary tableNext reaction cup pipe can be moved to corresponding position, the reaction cup pipe of sky is removed again afterwards, puts and fills reaction cupReaction cup pipe.The above is simple to operate, is less prone to error, and then ensure that being smoothed out for detection.
Brief description of the drawings
The present invention is described in further detail below in conjunction with accompanying drawing.
Fig. 1 is the structural representation in reaction cup storehouse of the present invention.
Fig. 2 is the structural representation that reaction cup storehouse of the present invention removes Double Tops lever apparatus.
Fig. 3 is the structural representation that reaction cup storehouse of the present invention removes shell.
Fig. 4 is the profile that reaction cup storehouse of the present invention removes Double Tops lever apparatus.
Fig. 5 is the structural representation of Double Tops lever apparatus of the present invention.
Fig. 6 is the assembling figure of reaction cup pipe of the present invention and reaction cup.
Fig. 7 is the structural representation of reaction cup pipe of the present invention.
Label is as follows corresponding to component names in figure：
1st, shell；3rd, reaction cup storehouse；31st, the first bottom plate；32nd, the first fixing axle；33rd, the first motor；34th, reaction cup pipe；35th, reaction cup；36th, top rotary table is reacted；37th, lower rotary table is reacted；38th, double-pole motor；39th, screw mandrel；310th, Double Tops rod bearing；311st, Double Tops rod guide；312nd, double-pole sliding block；313rd, support；314th, supporting plate；315th, yardstick；316th, a glass sensor is pushed away；317th, cavity；318th, shell fragment；319th, reaction cup pipe clamp groove；320th, pipe clamping pieces are reacted；321st, through hole；322nd, sensing section；323、Reaction cup storehouse motion sensor；324th, scanner；325th, scanner window；326th, the first axle sleeve；327th, clutch shaft bearing；328th,One big belt wheel；329th, the first small pulley；330th, the first belt；331st, light barrier；332nd, reaction cup storehouse overhead door；333rd, pulling buckle；334th, overhead door signal transducer；335th, reaction cup storehouse pillar；336th, pushing block.
Embodiment
Below in conjunction with the accompanying drawings and embodiment the present invention is described in further detail：
As the embodiment in reaction cup storehouse of the present invention, as shown in Figure 1, Figure 2, shown in Fig. 3, Fig. 4, Fig. 5, Fig. 6 and Fig. 7, wrapInclude shell 1, Double Tops lever apparatus, the first bottom plate 31, the first fixing axle 32, the first motor 33, reaction cup pipe 34, reaction cup 35, anti-Top rotary table 36 and reaction lower rotary table 37 are answered, the shell 1 is by the first fixing axle 32, the first motor 33, reaction cup pipe 34, reaction cup35th, react top rotary table 36 and reaction lower rotary table 37 is wrapped in inside, the lower end of first fixing axle 32 is fixed on described firstOn bottom plate 31, the reaction top rotary table 36 and reaction lower rotary table 37 are set with the upper end of first fixing axle 32 withEnd, and rotated under the drive of the first motor 33 and first pulley device around the first fixing axle 32, the superposition of reaction cup 35 is setInside reaction cup pipe 34, the top and bottom of the reaction cup pipe 34 are installed on reaction top rotary table 36 and reaction lower rotary table respectivelyOn 37, the Double Tops lever apparatus is fixed on first bottom plate 31 by support meanss, and Double Tops lever apparatus is located at the reactionThe top of top rotary table 36, and directly over reaction cup pipe 34.It will be superimposed upon inside reaction cup pipe 34 by Double Tops lever apparatusReaction cup 35 is released downwards one by one, on the relevant position that the reaction cup 35 of release drops in reaction tray, when a reactionAfter reaction cup 35 in cup pipe 34 has used, the first motor 33 rotates, and then drives reaction top rotary table 36 and reaction lower rotary table37 rotate, and the reaction cup pipe 34 of sky are removed below Double Tops lever apparatus, another reaction cup pipe 34 for filling reaction cup 35 movesMove immediately below Double Tops lever apparatus.
In the present embodiment, the Double Tops lever apparatus includes two double-pole motors 38, two screw mandrels 39, Double Tops rod bearings310th, two Double Tops rod guides 311 and two pieces of double-pole sliding blocks 312, the support meanss include support 313 and supporting plate 314,The supporting plate 314 is fixed on first bottom plate 31 by support 313, the Double Tops rod bearing 310 and two double-polesMotor 38, which is parallel to each other, to be fixed on the surface of the supporting plate 314, and two Double Tops rod guides 311 are vertical and parallel are fixed onOn Double Tops rod bearing 310, two pieces of double-pole sliding blocks 312 are slidably connected with two Double Tops rod guides 311 respectively, under two screw mandrels 39End is connected with two spirals of double-pole motor 38 respectively, and upper end is connected with two pieces of double-pole sliding blocks 312 respectively.When double-pole electricityWhen machine 38 rotates, screw mandrel 39 moves downward, and then withstands the reaction cup 35 inside reaction cup pipe 34, after moving a segment distance,A nethermost reaction cup 35 departs from reaction cup pipe 34 in reaction cup pipe 34, and the double-pole sliding block 312 of the upper end of screw mandrel 39 is sameAlong the slide downward of Double Tops rod guide 311.
In the present embodiment, the side on the Double Tops rod bearing 310 positioned at double-pole guide rail 311 is provided with a yardstick vertically315, it is provided with positioned at the side of yardstick 315 on the double-pole sliding block 312 and pushes away glass sensor 316, it is described to push away glass sensor 316Follow double-pole sliding block 312 to move up and down, and counted by yardstick 315.By yardstick 315 and push away glass sensor 316Count the quantity of reaction cup 35 for being apparent that the inside of reaction cup pipe 24 is remaining.
In the present embodiment, the reaction cup pipe 34 includes two cavitys 317 being parallel to each other, and the superposition of reaction cup 35 is put into twoIn individual cavity 317, the lower end of reaction cup pipe 34 is provided with shell fragment 318 around two cavitys 317.The top of reaction cup 35 of the top is setA pushing block 336 is equipped with, the lower end of screw mandrel 39 and the pushing block 336 are inconsistent.The modes of emplacement of superposing type can be effectively sharpWith space, and then reduce the placement region of reaction cup 35, settings of the shell fragment 318 can effectively clamp bottom one reactsCup 35.
In the present embodiment, the neighboring of the reaction top rotary table 36 is provided with a circle reaction cup pipe clamp groove 319, each reactionReaction pipe clamping pieces 320 are provided with cup pipe clamp groove 319, the reaction lower rotary table 37 is provided with a circle and the reaction cup pipe clamp groove phaseCorresponding through hole 321, the quantity of the through hole 321 are twice of reaction cup pipe clamp groove 319, and two through holes 321 are anti-for oneCup pipe clamp groove 319 is answered, the upper end of reaction cup pipe 34 is caught in the reaction pipe clamping pieces 320, and lower end is inserted in two through holes 321.It is convenient to use by the way that reaction cup pipe 34 is placed in reaction cup pipe clamp groove 319, and by reacting the fixed form of pipe clamping pieces 320Change reaction cup pipe in family.
In the present embodiment, the reaction top rotary table 36 is provided with sensing section 322, and the supporting plate 314 is provided with reactionCup storehouse motion sensor 323, the sensing section 322 and reaction cup storehouse motion sensor 323 are located on same circumference.It is described anti-Cup storehouse motion sensor 323 and the setting of sensing section 322 is answered effectively to record making for the internal-response cup pipe 34 of reaction cup storehouse 3Use situation.
In the present embodiment, the reaction cup storehouse 3 also includes scanner 324, and scanner window 325 is provided with shell 1.
In the present embodiment, the outer cover of the first fixing axle 32 is provided with the first axle sleeve 326, first axle sleeve 326 andTwo clutch shaft bearings 327 are provided between one fixing axle 32, the first pulley device includes the first big belt wheel 328, the first small bandThe belt 330 of wheel 329 and first, first small pulley 329 are fixed in the output end of first motor 33, and described first is bigBelt wheel 328 is installed on the lower end of first axle sleeve 326, by the first belt 330 by the first big belt wheel 328 and the first small pulley329 are connected.
In the present embodiment, three pieces of light barriers 331 are provided between the reaction top rotary table 36 and reaction lower rotary table 37.
In the present embodiment, the shell 2 includes a reaction cup storehouse overhead door 332, the top of reaction cup storehouse overhead door 332 with it is outerRemaining position of shell 1 is hinged, and bottom is fixed by pulling buckle 333, and overhead door sensing is provided with reaction cup storehouse overhead door 332Device 334.Using the opening ways of upset, user's operation is more convenient, and sets overhead door signal transducer 334 effectively to superviseControl the open and-shut mode of reaction cup storehouse overhead door 332.
In the present embodiment, the lower surface of first bottom plate 31 is provided with reaction cup storehouse pillar 335, passes through reaction cup storehouse branchReaction cup storehouse 3 is fixed on support body by post 335（Not shown in figure）On.
A kind of full-automatic illumination immunity analysis instrument, including above-described reaction cup storehouse 3.