A kind of Multifunctional inspection sample extraction separatorTechnical field
The present invention relates to chemical analysis instrument technical fields, and in particular to a kind of Multifunctional inspection sample extraction separation dressIt sets, is suitable for detecting the pretreatment operations such as biogenetic products nucleotide, the resolution of base sample, purification, separation, be also suitable simultaneouslyIn other preparations for carrying out being separated by solid-liquid separation work or detection and analysis operation.
Background technology
Nucleotide, base contain abundant purine, and mankind's Excess free enthalpy will induce the diseases such as gout, hyperuricemia, serious shadowRing the health of kidney, skeletal joint.However currently, Partial Food drink enterprise is to improve mouthfeel and delicate flavour, in food arbitrarilyAdd guanylic acid and inosinicacid（I+G）, yeast extract, the high purine substance such as seafood extract, cause purine in food and containAmount increases, and is not marked in detail in food labelling.Therefore, therefore it provides it is a kind of quickly and accurately fast in detection foodThe technology of purine content allows business and consumer to grasp food purine content information, and improving the disease-resistant level of health care to the mankind has emphaticallyThe Practical significance wanted.Nucleotide, base class product are also one of food and medicinal industry important source material, and the improvement of detection technique willThe raising for promoting food manufacturing level, food security safeguard level, may advantageously facilitate economic development and social harmony.
The product majority of purine-containing is manufactured by biology, nucleotide, base（Purine and pyrimidine）Mostly with other kind of substanceIn conjunction with or coexist, ingredient is complex.Accurate Determining is wanted, complicated sample pretreatment usually need to be first carried out, step includes digestionDegradation, chemical derivatization, impurity（Active ingredient）The links such as absorption or precipitation, liquid or solid separation, current general sample detectionStrong acid decomposition, acid-base neutralization, denaturation precipitation, separating treatment, extraction target component need to be carried out, therefore egg need to be removed with multiple meansIn vain, the interference components such as polysaccharide, auxiliary material, byproduct of reaction.But in existing conventional isolation techniques, each preprocessing means can onlyUsing corresponding utensil, with digestion tube, derivative pipe, impurity as digestion degradation, chemical derivatization operation（Active ingredient）AbsorptionOr precipitation uses beaker, flask or reactor；Lock out operation uses funnel, filter, centrifuge etc..These customary furnishings functionsIt is single, in a large amount of inspection product of processing or step complexity, often there are a large amount of utensil needs and use and cleaning, utensil is needed to account for afterWith occurring the problems such as Liquid Residue loss or the improper dilution of sample in working space, cumbersome, link switching process, causeProduce detection great work intensity, the defects of efficiency is low, detection error is big or deficiency.
It therefore, can be notable in view of the above-mentioned problems, the present invention provides a kind of Multifunctional inspection sample extraction separatorImproving needs to carry out complicated pretreated nucleotide, base in biogenetic products（Purine and pyrimidine）The detection of sample and similar products is imitatedRate reduces processing links and required a variety of utensils, and reducing conventional method need to handle through multiclass utensil, shift and sample is caused to damageLose or make the detection error being diluted to；Also, the present invention, which also has, reduces labor intensity, accuracy in detection is improved, in a large amount of samplesWhen product examine is surveyed, there is processing efficiently clear superiority.For other preparations being separated by solid-liquid separation or detection and analysis fieldOperation, it is all or part of to use the present apparatus also convenient performance having the same.
Invention content
The present invention provides a kind of Multifunctional inspection sample extraction separators, suitable for detecting disappearing for the sample containing baseThe pretreatment operations such as solution, purification, separation, while being also applied for other similar pretreatment operations.
In order to realize that the technical purpose of the present invention, the present invention adopt the following technical scheme that.
A kind of Multifunctional inspection sample extraction separator, including apparatus main body, described device main body include being located at topReaction unit, the extraction element at middle part and the device for storing liquid of lower part, be located at device for storing liquid bottom valve, be connected and fixed reactionFirst Quick hoop of device and extraction element is connected and fixed the second Quick hoop of extraction element and device for storing liquid, described anti-It answers and is provided with sealed bolster plate between device and extraction element, telescopic chute, institute are connected between the extraction element and device for storing liquidThe lower end for stating telescopic chute is provided with limit rubber gasket, and seal gasket is disposed between the extraction element and device for storing liquidCircle, filter medium, telescopic chute and U-shaped rubber gasket, described device main body will be anti-by the first Quick hoop and the second Quick hoopDevice, extraction element and device for storing liquid is answered to be connected as one.
Further, the telescopic chute is H shape shapes, and the middle part of telescopic chute is the slab construction for being provided with multiple trepannings.
Further, multiple conduction holes are provided on the U-shaped rubber gasket inside the device for storing liquid, the conduction hole is located atThe periphery of trepanning.
Further, it is provided with that hole number is identical, the protrusion of the corresponding sealing in position with drainage in the middle part of the telescopic chute.
Further, the filter medium is one kind in sieve, filter paper or filter membrane.
Further, multiple fixed hex bolts one of reinforcement, the telescopic chute are additionally provided on the top of the telescopic chuteLower part be provided with and multiple reinforce fixed hex bolts two.
Further, the hex bolts two passes through limit rubber gasket and is screwed in telescopic chute with threaded engagement and formed and connectsIt connects.
Further, the device for storing liquid is along limit rubber gasket direction axial stretching.
Further, valve is further connected on the valve to take over.
Further, the main body of the reaction unit, extraction element and device for storing liquid is by stainless steel, glass or other accordancesThe similar material that can be required is made, such as with the good alloy material of high intensity, high rigidity, anticorrosive property；The interior table of reaction unitThere are PTFE- polytetrafluoroethylene (PTFE) material linings in face.
The invention has the advantages that：The present invention provides a kind of Multifunctional inspection sample extraction separators, adoptWith integrated apparatus, digestion degradation, chemical derivatization, impurity can be completed together according to actual test needs（Active ingredient）AbsorptionOr all processes such as precipitation, liquid or solid separation, or wherein several processing procedures are completed according to actual needs.
Compared with existing extraction and separation technology or device, a kind of Multifunctional inspection sample extraction separation provided by the inventionDevice, no matter in terms of purposes diversity, simple operation, or in terms of reducing analytical error, saving utensil occupied spaceWith significant progress, the deficiency of conventional method is overcome.
Description of the drawings
To describe the technical solutions in the embodiments of the present invention more clearly, make required in being described below to embodimentAttached drawing is briefly described：
Fig. 1 is present invention reaction or extraction status architecture schematic diagram；
Fig. 2 is filtration condition structural schematic diagram of the present invention；
Fig. 3 is trepanning schematic diagram on telescopic chute tablet of the present invention；
Fig. 4 is conduction hole schematic diagram on U-shaped rubber gasket of the present invention；
Fig. 5 is present invention limit rubber gasket schematic diagram.
In figure：1- reaction units；11- sealed bolster plates；2- extraction elements；21- filter mediums；3- device for storing liquid；31- valvesDoor；32- valves are taken over；4- telescopic chutes；41- trepannings；42- protrusions；The first Quick hoops of 51-；The second Quick hoops of 52-；61- is closeSealing washer；62- limits rubber gasket；63-U shape rubber gaskets；64- conduction holes；71- hex bolts one；72- hex bolts two.
Specific implementation mode
In order to make the technical problems, technical solutions and beneficial effects solved by the present invention be more clearly understood, with reference toAccompanying drawings and embodiments, the present invention will be described in further detail.It should be appreciated that specific embodiment described herein is only usedTo explain the present invention, the present invention is not limited.
Referring to Fig.1, shown in Fig. 2, Fig. 3, Fig. 4 and Fig. 5, the present invention provides a kind of separation of Multifunctional inspection sample extraction to fillIt sets, including apparatus main body, described device main body includes superposed reaction unit 1, the extraction element 2 at middle part and the storage of lower partLiquid device 3 is located at the valve 31 of 3 bottom of device for storing liquid, is connected and fixed the first Quick hoop of reaction unit 1 and extraction element 251, it is connected and fixed the second Quick hoop 52 of extraction element 2 and device for storing liquid 3, between the reaction unit 1 and extraction element 2It is provided with sealed bolster plate 11, telescopic chute 4, the lower end of the telescopic chute 4 are connected between the extraction element 2 and device for storing liquid 3It is provided with limit rubber gasket 62, fluid sealant washer 61 is disposed between the extraction element 2 and device for storing liquid 3, filtering is situated betweenMatter 21, telescopic chute 4 and U-shaped rubber gasket 63, described device main body will be anti-by the first Quick hoop 51 and the second Quick hoop 52Device 1, extraction element 2 and device for storing liquid 3 is answered to be connected as one.
The telescopic chute 4 is H shape shapes, and the middle part of telescopic chute 4 is the slab construction for being provided with multiple trepannings 41.The storage8-16 conduction hole 64 is provided on U-shaped rubber gasket 63 inside liquid device 3, the conduction hole 64 is located at the periphery of trepanning 41,The middle part of the telescopic chute 4 is provided with the protrusion 42 of the sealing corresponding with conduction hole 64 of identical quantity.The filter medium 21 isOne kind in sieve, filter paper or filter membrane.The top of the telescopic chute 4 is additionally provided with 4-10 and reinforces fixed hex bolts one71, the lower part of the telescopic chute 4 is provided with 4-10 and reinforces fixed hex bolts 2 72, and the hex bolts 2 72 passes through limitPosition rubber gasket 62 simultaneously screws in telescopic chute formation connection with threaded engagement.The device for storing liquid 3 is along 62 direction of limit rubber gasketAxial stretching is further connected with valve take over 32 on the valve 31.
How the principle of its work is realized if being illustrated to the device of the invention further below.Reaction unit 1 is responsible for sampleProduct clear up function, by the way that by cylindric reaction unit 1, the sealed bolster plate 11 between reaction unit 1 and extraction element 2 is closeEnvelope, and after loading onto the first Quick hoop 51, stand upside down and place, as Specimen eliminating device, can be used for various strong acid, highly basic and in it is warm-naturedWith the chemical breakdown under the conditions of grade（It is derivative）Or biological enzymatic decomposition（It is derivative）, decompose Applicable temperature and be 0-125 DEG C, be applicable in pressureNo more than 103.4kPa（1.05kg/cm2）.After the completion of reaction, the first Quick hoop 51, sealed bolster plate 11 are opened, can be carried out downThe operations such as the stopping of reaction, soda acid adjustment, organic solvent deposit, denaturation, extraction or the adsorption treatment of one step flow.
Extraction element 2 and device for storing liquid 3 are responsible for extraction and the filtering function of device.Extraction element 2 and sump assemblies 3 areCylindrical shape is fastenedly connected integrally by hex bolts 1, the hex bolts 2 72 on telescopic chute 4.The middle part of telescopic chute 4It is provided with the protrusion 42 of sealing corresponding with conduction hole 64, after loading onto the second Quick hoop 52, protrusion 42 just seals up U-shaped rubber cushionConduction hole 64 on circle 63, by the sealed bottom of extraction element 2.At this point, in isolation between extraction element 2 and device for storing liquid 3State can carry out subsequent extracted or the solid cleaning of sample in extraction element 2, release protrusion 42 and U-shaped rubber gasket 63Sealing occlusion, then further realize liquid filtering function.
It, can be by device for storing liquid 3 along limit glue after the second Quick hoop 52 for removing connection extraction element 2 and sump assemblies 362 direction of washer is axially stretched, and maximum tension distance is supported for extremely limit 62 lower edge of rubber gasket to the upper edge of hex bolts 2 72.It is logicalIt crosses and stretches device for storing liquid 3, the inner space of device for storing liquid 3 is made to become larger, generate local decompression, and then make in extraction element 2Liquid is filtered to lower part sump assemblies 3, realizes filtering function.
Further, it closes the valve 31 of device for storing liquid 3 bottom, and device for storing liquid 3 is pulled back along maximum tension distance to carryingWhen taking device 2, at this point, the local positive pressure for process generation of pulling back by telescopic chute 4, makes gas from a side of device for storing liquid 3 to carryingIt takes the side of device 2 to escape, and then the accumulation sediment on impact filtration medium 21, filter medium 21 is reversely dredged, is realizedStrainability improves or realizes the preliminary cleaning of filter medium.
In Multifunctional inspection sample extraction separator provided by the invention, digestion degradation, impurity（Active ingredient）It inhalesThe processing such as attached or precipitation, liquid or solid separation, which are arranged in same covering device, to be completed.The integrated design device has knotStructure simple and compact, good airproof performance, movement is smooth, stable and reliable for performance, multiple functional, installing and dismounting is quick, easy to clean etc. moreKind advantage.It can be according to the purposes purpose flexible combination device of processing, reaction unit 1, extraction element 2, the telescopic chute of different capabilities4, the engagement of sump assemblies 3 bore specification is consistent, and docking coincide, and significantly reduces artificial detection error, improves detection efficiency, changesIt has been apt to operating environment and working condition.Apparatus of the present invention main body is made of stainless steel, glass or similar material, in reaction unit 1The lining material on surface is PTFE- polytetrafluoroethylene (PTFE), enhancing present apparatus acid and alkali-resistance, oxidant, organic solvent corrosion and high temperature resistant,High-voltage performance, the lining of 1 inner surface of the reaction unit can also be it is other have meet acid and alkali-resistance, antioxidant, You JirongOther lining materials of agent corrosion and high temperature resistant, high-voltage performance.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present inventionGod and any modification made within principle, equivalent replacement etc., should all be included in the protection scope of the present invention.