The present application claims the benefit of a "synergistic pesticidal composition and related methods" application having U.S. provisional patent application serial No. 61/894,026 filed on 2013, 10 and 22 months.
Disclosure of Invention
The term "synergistic effect" or grammatical variations thereof as used herein refers to and includes a synergistic effect encountered when two or more active compounds are combined, wherein the combined activity of the two or more active compounds exceeds the sum of the activities of the individual active compounds.
The term "synergistically effective amounts" as used herein refers to and includes amounts of two or more active compounds which provide a synergistic effect as defined above.
The term "pesticidally effective amount" as used herein refers to and includes an amount of active pesticide that produces an adverse effect on at least one pest, wherein the adverse effect may include deviations from natural development, killing, or regulation, and the like.
As used herein, the term "control" or grammatical variations thereof refers to and includes regulating the number of living pests or regulating the number of living eggs of a pest or both.
The term "juvenile hormone mimicking compound" as used herein refers to and includes any insecticide classified by the Insecticide Resistance Action Committee (IRAC) within IRAC mode of action group 7C based on the best existing evidence of mode of action.
In a particular embodiment, the pesticidal composition comprises a synergistically effective amount of a juvenile hormone mimicking compound in combination with a pesticide selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof.
It is understood that a pesticide selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propionamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propionamide (II), or any agriculturally acceptable salt thereof, may be oxidized to the corresponding sulfone in the presence of oxygen.
As shown in the examples, the presence of synergistic effects was determined using the method described in colbys.r. "calibrated synergistic responses of pharmacological compositions," Weeds,1967,15, 20-22.
Surprisingly, it has been found that the pesticidal compositions of the present disclosure have a lower level of combined concentration of the juvenile hormone mimic compound used and the pesticide (I), (II) or any agriculturally acceptable salt thereof, with superior pest control than can be achieved when the juvenile hormone mimic compound and the pesticide (I), (II) or any agriculturally acceptable salt thereof are applied alone. In other words, the synergistic pesticidal composition is not a mere mixture of two active compounds, resulting in a combination of properties of the active compounds used in the composition.
In some embodiments, a pesticidal composition may comprise a synergistically effective amount of pyriproxyfen (pyriproxyfen) in combination with a pesticide selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof.
Table 1A shows the weight ratio of the insecticides (I), (II) or any agriculturally acceptable salt thereof to the juvenile hormone mimic compound in the synergistic insecticidal composition. In some embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be about 20:1 to about 1: 20. In some embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be about 15:1 to about 1: 15. In some embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be about 10:1 to about 1: 10. In some embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be about 5:1 to about 1: 5. In some embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be about 4:1 to about 1: 4. In some embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be about 3:1 to about 1: 3. In some embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be about 2:1 to about 1: 2. In some embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be about 1: 1. In addition, the weight ratio limits of the pesticide to the juvenile hormone mimic compound in the previous embodiments may be interchanged. By way of non-limiting example, the weight ratio of the insecticide to the juvenile hormone mimicking compound may be about 1:3 to about 20: 1.
TABLE 1A
| Numbering | Weight ratio range of pesticide I or II to juvenile hormone mimic compound |
| 1 | 20:1 to 1:20 |
| 2 | 15:1 to 1:15 |
| 3 | 10:1 to 1:10 |
| 4 | 5:1 to 1:5 |
| 5 | 4:1 to 1:4 |
| 6 | 3:1 to 1:3 |
| 7 | 2:1 to 1:2 |
| 8 | 1:1 |
The weight ratio of the insecticides (I), (II) or any agriculturally acceptable salt thereof to the juvenile hormone mimicking compound contemplated as synergistic insecticidal compositions may be described as X: Y; wherein X is the weight parts of the pesticides (I), (II) or any agriculturally acceptable salt thereof and Y is the weight parts of the juvenile hormone mimic compound. The weight fraction value for X ranges from 0< X ≦ 20 and the weight fraction value for Y ranges from 0< Y ≦ 20, as illustrated in Table 1B. By way of non-limiting example, the weight ratio of pesticide to juvenile hormone mimic compound may be about 20: 1.
The weight ratio range of the insecticides (I), (II) or any agriculturally acceptable salt thereof to the juvenile hormone mimicking compound contemplated as synergistic insecticidal composition can be described as X1:Y1To X2:Y2Wherein X and Y are as defined above. In a particular embodiment, the weight ratio range may be X1:Y1To X2:Y2Wherein X is1>Y1And X2<Y2. By way of non-limiting example, the weight ratio of the insecticide to the juvenile hormone mimicking compound may range from about 3:1 to about 1: 3. In some embodiments, the weight ratio range may be X1:Y1To X2:Y2Wherein X is1>Y1And X2>Y2. By way of non-limiting example, the weight ratio of the insecticide to the juvenile hormone mimicking compound may range from about 15:1 to about 3: 1. In further embodiments, the weight ratio range may be X1:Y1To X2:Y2Wherein X is1<Y1And X2<Y2. By way of non-limiting example, the weight ratio of the insecticide to the juvenile hormone mimicking compound may range from about 1:3 to about 1: 20.
TABLE 1B
Parts by weight of insecticides (I or II) (X)
Table 1C shows the weight ratio of the insecticides (I), (II), or any agriculturally acceptable salt thereof, to the juvenile hormone mimicking compound in the synergistic insecticidal composition according to the specific embodiments of the present disclosure.
In some particular embodiments, the weight ratio of the pesticides (I), (II), or any agriculturally acceptable salts thereof, to the juvenile hormone mimicking compound may be not greater than about 6.39: 1. In further embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be no greater than about 1.6: 1. In yet further embodiments, the weight ratio of the pesticide to the juvenile hormone mimicking compound may be no greater than about 0.40: 1.
TABLE 1C
The weight ratio of the pesticides (I), (II) or any agriculturally acceptable salt thereof to the juvenile hormone mimic compound in the synergistic pesticidal composition may vary and is different from those described in table 1A, table 1B and table 1C. The skilled person realizes that the combination of synergistically effective amounts of active compounds may thus vary according to various main conditions. Non-limiting examples of such primary conditions may include pest species, crop species, mode of application, timing of application, weather conditions, soil conditions, or topographical features, among others. It is understood that a synergistically effective amount of the juvenile hormone mimicking compound and the pesticide (I), (II) or any agriculturally acceptable salt thereof can thus be readily determined by the skilled person on the basis of the prevailing conditions.
In some embodiments, the pesticidal composition may comprise a synergistically effective amount of a juvenile hormone mimicking compound in combination with a pesticide, and a phytologically acceptable inert carrier (e.g. a solid carrier or a liquid carrier), said pesticide being selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof.
In a further embodiment, the pesticidal composition may further comprise at least one additive selected from a surfactant, a stabilizer, an emetic, a disintegrant, an antifoaming agent, a wetting agent, a dispersant, a binder, a dye, a filler, or a combination thereof.
In a particular embodiment, each of the pesticides (juvenile hormone mimicking compound, and a pesticide selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof) may be formulated alone as any of a wettable powder, an emulsifiable concentrate, an aqueous or liquid flowable, a suspension concentrate, or a conventional formulation for pesticides, it is then tank mixed with water or other liquid for application as a liquid spray mixture in the field. Separately formulated insecticides may also be applied sequentially as desired.
In some embodiments, the synergistic pesticidal composition may be formulated as a more concentrated primary composition that is diluted with water or other diluent prior to use. In this embodiment, the synergistic pesticidal composition may further comprise a surfactant.
In a particular embodiment, the method of protecting a plant from insect infestation and attack comprises contacting the plant with an insecticidal composition, the pesticidal composition comprises a synergistically effective amount of a juvenile hormone mimicking compound in combination with a pesticide, the insecticide is selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof.
In some embodiments, the pesticidal composition may be in solid form. Non-limiting examples of solid forms may include powder, dust or granular formulations.
In other embodiments, the pesticidal composition may be in the form of a liquid formulation. Examples of liquid forms may include, but are not limited to, dispersions, suspensions, emulsions, or solutions in a suitable liquid carrier. In particular embodiments, the synergistic pesticidal composition may be in the form of a liquid dispersion, wherein the synergistic pesticidal composition may be dispersed in water or other liquid carrier suitable for agriculture.
In certain embodiments, the synergistic pesticidal composition may be in the form of a solution in a suitable organic solvent. In one embodiment, spray oils, which are widely used in agricultural chemistry, may be used as organic solvents for synergistic pesticidal compositions.
In a particular embodiment, a method of controlling pests comprises applying a pesticidal composition in the vicinity of a pest population, wherein the pesticidal composition comprises a synergistically effective amount of a juvenile hormone mimicking compound in combination with a pesticide, the insecticide is selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof.
Control of pests can be achieved by applying an insecticidally effective amount of a synergistic insecticidal composition in the form of: sprays, topical treatment forms, gels, seed coatings, microcapsules, systemic absorption forms (systemicuptake), baits, ear tags, boluses, sprays (foggers), fumigants, aerosols or powders and the like.
These disclosed insecticidal compositions can be used, for example, as nematicides, acaricides (acarcides), miticides (miticides), and/or molluscicides.
The insecticidal compositions of the present disclosure can be used to control a wide variety of insects. As one non-limiting example, in one or more embodiments, the pesticidal composition may be used to control one or more pests of at least one of: phylum Arthropoda (PhyumArthropoda), phylum nematoda (PhyumNematoda), subdivision of the chelidan (SubphylumCilerata), subdivision of the Popoda (SubphylumMyriapoda), subdivision of the Hexapoda (SubphylumHexapoda), Insecta (ClassInsecta), Arachnida (ClassSymphyta) and Symphyta (ClassSymphyta). In at least some embodiments, the methods of the present disclosure can be used to control one or more pests of at least one of: insecta (ClassInsecta) and Arachnida (ClassArachnida).
As one non-limiting example, in one or more embodiments, the methods of the present disclosure can be used to control one or more pests of at least one of: phylum Arthropoda (PhyumArthropoda), phylum nematoda (PhyumNematoda), subdivision of the chelidan (SubphylumCilerata), subdivision of the Popoda (SubphylumMyriapoda), subdivision of the Hexapoda (SubphylumHexapoda), Insecta (ClassInsecta), Arachnida (ClassSymphyta) and Symphyta (ClassSymphyta). In at least some embodiments, the methods of the present disclosure can be used to control one or more pests of at least one of: insecta (ClassInsecta) and Arachnida (ClassArachnida).
In further embodiments, the methods of the present application may be used to control Coleoptera (Coleoptera) pests (beetles), including, but not limited to, pissodes species (acanthoscelides pp.) (weevils), pissodes species (acanthoscelides obtectus) (common pissodes), white wax narrow gigantes (agrilsponenis) (curly willow narrow gigantes), Wireworm species (agriotes spp.) (Wireworm), phoshoulder beetles (anophora glabipinnis) (long horn petunia asia), gossypium species (athrominus spp.) (elephantopis), gossypium species (athromonaceae), gossypium gossypii (athrominus grandis) (gossypium), gossypium species (athrominus gracili), gossypium species (apaludwigia sp.), gossypii sponus sp.) (athyri), gossypium species (athyri nigrum nigra), gossypium species (gruspongiosa), setaria nigra species (pacifica), or beetles (grubes (pacifica), or beetle) (pacifica), or black beetles (grubes (pacifica), or beetle) (pacific beetles) (or black beetles (e.), elephant (bruchus pisorus) (pea weevil), Cacoesia species (cacoesospp.), callerythematodes (calosobsculus) (southern cowpea weevil), yellow-spotted beetles (carpohophyllus eminensis), beet beetles (Cassidavittata), asparagus species (cerostreae), Cerotoma species (cerotomaphyssop), red-spotted beetles (cabbage beetles), red-spotted beetles (cabbage beetle), red-spotted beetles (cabbage beetles) (western red beetles), red-spotted beetles (cabbage beetles) (western beetles), red-spotted beetles (cabbage beetles) (western beetles (cabbage), red beetles (cabbage beetles) (western beetles) (western beetles), red beetles (western beetles), red beetles (western beetles) (western, Examples of plants include, but are not limited to, crohns planiculorum (crohns), truestar planiculorum (crohns), trustle planiculorum (turkey beetle), cteniciera species (cteceraras pp.) (nematode), weevil species (culiolsp.) (weevil), bullnose beetle (cyclepia sp.) (grub), melissa miciformis (cyclindraurea), phyllocladus filiformis (cyclindus), mangosteen (coprinus. crispatus) (coprinus), mangosteen (coprinus. crispatus) (dendrobius), bark beetle (bark beetle), coffee beetle (coffee bean (beetle), bark beetle (bark beetle), stem (bark beetle), bark beetle (bark beetle), bark beetle (stem (bark beetle), bark beetle (stem), stem (borer), leaf beetle (stem, borer, cornia (stem, cornus), borer, cornus (cornus, cornus (cornus) and stem, cornus (cornus) of cornus (cornus ) or cornus (cornus) or cornus) may, cornus (cornus) may, cornus, The species ips (ipspp.) (echinocandis (enggravers)), diabeto (lasiodema sericorne) (tobacco beetle (cigarette)), diabeto (leptinotarsa decemlineata) (potato beetle), liogyfuscus, liogyssularis, elephantopus oryzae (lissoropus) (rice weevil), silverfish species (lycopersicon), beetle (orange beetle)/beetle (powdepothistle)), maygeropsis (septoria judai), megasella (megasella), beetle (beetle), corn beetle (meotusmura), mellegungensis (mellegunggegegegegeella), elephantopis (yellow beetle), meldonia (yellow beetle), yellow beetle (yellow beetle, yellow, The rhynchophorus species (pantophorus spp.) (elephant), the gill-eating species (phyllophagassp.) (pentacyeja/juniper tortoise), the phyllophagacunana (diabolo family insects), the sterculia species (phynocystp.)), the popillia japonica (popillia japonica), the pissodes corniculatus (proteus striatus) (largegrainborn beetle), the pissodes oryzophilus (rhizophilus beetle)), the rhynchophorus castus (rhizophilus gracilis) (rhizophilus), the rhizus rhynchophorus (leptus), the rhynchophorus microerus (leptus), the setus pisorus (trichoderma), the setum (trichoderma), the setosum (trichoderma), the trichoderma (trichoderma viride) (trichoderma), the trichoderma (trichoderma) species (trichoderma), the trichoderma (trichoderma) and the trichoderma (trichoderma) of the trichoderma (e (trichoderma) of the rice plant), the trichoderma (trichoderma) and the trichoderma (trichoderma) of the trichoderma (, Triboliumconjugatum (Triboliumconjugale), bark beetle (moth) and Zabrustenebioides.
In other embodiments, the methods of the present application may be used to control Dermaptera pests (earwigs).
In further embodiments, the methods of the present application may be used to control a vein-wing (Dictyoptera) pest (cockroaches), including, but not limited to, german cockroach (blattagermacea), blattaria orientalis (blattacloacah), blattaria bicolor (roach), blattaria bicolor (parcobiana), periplaneta americana (americana), periplaneta australiana (australoloasiroach), periplaneta americana (brown cockroach (bronchus)), periplaneta fuliginosa (brown cockroach), and periplaneta fuliginospora fuliginosa (brown stripe), periplaneta smoky cockroach (periplaneta), and periplaneta fuliginosa (cockroach).
In further embodiments, the methods of the present application may be used to control Diptera (Diptera) pests (flies) including, but not limited to, aedes species (Aedesspp.) (mosquitoes), lucerne fly (agromya frontalis) (alfafa palmoplanta), agromyza species (agromyza spp.) (leaf miner), trypanosoma species (anastrep), trypanosoma species (drosophila), callimastix (anaphila), callitrichia (diaphasps), anophe species (anophe), plasmopara anophe species (anopheles), bactrocera dorsalis (chrysoideus), bactrocera (bactrocera), trypanosoma latus (cerastipa), trypanosoma latus (cerana), trypanosoma latus (cera (cerana), trypanosoma latus (cera) fly (trypanosoma latus), trypanosoma latus (cera) or (trypanosoma latus), trypanosoma latus (trypanosoma, Culex species (Culexspp.) (mosquito), phyllocladus (Dasineuraspp.) (gallmidges)), oilseed rape leaf gall midges (Dasineurabasic) (cabbage gall midge (cabbagagegalmidge)), groundfly species (Deliasplat.) (Delilasplat), groundfly species (Delilaptura) (seed fly (Seedcormagot)), Drosophila species (Drosophila), Vinegar fly (Vinegaflries)), Drosophila species (Fanniaxp.) (Home flies (diaplases)), yellow belly flies (Fanniella) (Haynia (yellowtail)), Greensis fly (cabbage fly) (cabbage fly (vegetable fly)), Greenfly (cabbage fly) (cabbage fly (yellowtail)), and cabbage fly (vegetable fly (cabbage fly)), and belly fly (Spilameracillus), and (housefly) (Hymenofly)), and yellow belly fly) (Haemaristius (cabbage fly (vegetable fly)), and leaf fly (cabbage fly)), and yellow fly (cabbage fly (vegetable fly)), and leaf fly (cabbage fly)) Musca species (Muscaspp.) (house flies), autumn flies (muscaautumnales) (facia flies), house flies (muscadoacross flies), sheep flies (oestermosovies) (sheep nose flies), european stem flies (ostrich) and (pig tail flies), beet spring flies (pepper flies), beet leaf flies (beet leaf flies), seed fly species (Phorbiaspp.), carrot stem flies (psilareosae) (carrot flies), cherry fruit flies (rhagletop flies) (cherry fruit flies), apple fruit flies (rhapontopsis) (apple maggots), apple fruit flies (apple red mud flies) (apple maggots), apple fruit flies (bovine sucking flies) (cow red mud flies) (cow yellow flies), cow fruit flies (cow red mud flies) (cow yellow flies).
In other embodiments, the methods of the present application may be used to control Hemiptera (Hemiptera), heteroptera (subpteroderma) pests (bugs), including, but not limited to, apolygus lucorum (acrophile), lygus lucorum (bletilla), lygus lucorum (chinchbug), cyrtorhinus americana (calophylloruicus), cyrtorhinus californica (calophyllorusboreus), cyrtorhinus californica (calophyllorusdorvechicus), cyrtosis tropicalis (cimexhephetis), lygus bugs (cimex lucorula), cyrtosis bugs (euschistus), euschistus crocatus, cereal grain, euschistus palmatus (euschistus), euschistus (leucoderma), euschistus (euschistus), euschistus (leucoderma), euschistus (leiocarpus (euschistus), euschistus (euschistosoma), euschistosoma (leiocarpus americana), euschistus) euschistosoma (euschistospora), euschistosoma (leiocarpus), euschistospora), euschistus) or leiocarpus (leiocarpus), euschistosporus) or leiocarpus (leiocarpus), euschistosporus), euschistospora), euschistostus) or leiocarpus (, Pseudolygus syriacus (Maconemiccushirsutus), Neurocarpusirostris, Oryza sativa (Nezarviridula) (southern stinkbug), lygus planterum (Phytocorisspp.) (Rheuptugs), Phytocoriscalifornius, Phytocorisrelatinius, Piezodourgiculidinii (Pasteur. serimbug)), Detebufagin quadrate (Poeciocapis sutureus) (fourstrilpentinbug), Psalvaccicola, Pseudactylaseae, Scotocoris, and Primulus species (Triatomaspongensis).
In further embodiments, the methods of the present application may be used for controlling Homoptera (Homoptera), cephalosub-order (Sub-Order Sachenorrhyncha) (Free-living semi-pteroid insects (Free-living Hemiptera)), and sternocosub-order (Sternorhyncha) (Plant-parasitic semi-pteroid insects) (aphids), scales, whiteflies (leafhoppers), leafhoppers (leafhoppers)), including, but not limited to, Pieris (Acrythinperus) (Pieris pisum), Coccinia (Adelsstepsis), Coccinia (Adelsia), Aleuroderma (Aleurodersella) (cabbage whitefly), Spirophilus (Aleuryphosphatella) (Aleuryphosatus), Aleuryphosaceus (Aleuryphosaceus), Aleuryphylla (Aleuryphylla), Aleuryphylla (Aphyllophora), Aleuryphosaurus (Aphyllus), Aleuryphosaceus (Aphis viridans), Aleuryphosaurus (Aphis), Aleuryphosaceus (Aphis viridae), Aleuryphosaria (Aphis, Aphis gossypium), Aleuryphosaurs) (Aphis, Aphis gossypium), Aleuryphi), Aleuryphosaurs (Aphis viridae (Aphis) and Aleuryphi), Aleuryphosaurs (Aphis viridae (Aphis) and Aleuryphosaurs), Aleuryphosaurs (Aleuryphosaurs), Aleuryphosaurs Aphis (Aleuryphosaurs), Aleuryphosaurs, Aleur, Potato long-hair aphid (autolorthumnoleni) (foxgloglephid), whitefly species (bemisiasp), whitefly (whitefly), whitefly (bemisiagarnetilii), whitefly (bemisiagarneti), whitefly (bemisiagarabici) (sweet potato whitefly), brachylouse (brachysolnoxius) (russian (russiaaphhis)), asparagus (brachynyasaparagi) (asparagus (agragusaaphid)), breynearhie, cabbage (brevicornebsiella) (cabbage), ceroplastes species (ceroplastessypsis), ceroplastes (ceroplastes), ceroplastes red (ceroplastes) (red wax orange), ceroplastes (ceroplastes), ceroplastes sp) (brown apple yellow meadow), ceroplastes (blackmeadow), ceroplastes (ceroplastes) (brown apple meadow), ceroplastes (red apple yellow meadow, red meadow, red meadow, red, mango yellow-line leafhopper (idiophagous nitidus) (mango leafhopper (mangoleaf hopper)), laodelphax striatellus (laodelphax striatellus) (small brown plant hopper (smallerophyllum), oyster species (lepidophysp.), long-tube aphid species (macrosiphilus spp.), euphorbia major (macrosiphorum macrosporum) (potato aphid (potatopaphiaphus), long-tube aphid (macrosiphum grandiflorum) (Englishgrangian), rose-tube aphid (macrosiphilus) (rose aphid), roseleaf of drynaria (grandiflorum), mahalanobium grandiflorum (brown rice), tomato leaf aphid (brown rice), brown rice leaf aphid (brown rice), black rice leaf aphid (brown rice), black rice leaf aphid (brown rice leaf), black rice leaf (brown rice leaf), black rice leaf rice (brown rice leaf, tomato seed (brown rice leaf rice, Plant species of the genus Laoderma (Philaenumspp.) (Laoderma laevigata), Rhizopus viticola (Phylloraphifolia) (Rhizopus viticola (grapephyloserra)), Lepidococcus niveus (Phyllospora speratus) (Lepidogrisella spronii (spruce), Lepidogra (Planococcus sp.) (mealykuporus), Lepidogra citroidea (Pseudococcus citri), Lepidogra (Pseudocera viridans) (Pseudocera viridula (Gracilaria), Pseudocera viridula (Gracilaria)), Pseudocera viridula (Pseudocera viridula (Gracilaria)), Pseudocera viridula (Fabricius), Pseudocera viridula (Fabricius) (Piper albus), Pseudocera viridula (Pseudocera), Pseudocera viridula (Pseudocera viridula), Pseudocera viridula (Pseudocera), Pseudocera viridula (Piper), Pseudocera viride (Piper), Pseudocera viride (Pilus), Pilus (Pilus), Piper (Piper viride), Pilus), Piper viride (Pilus), Pilus, Pi, The genus lecanicillium (theoaphisp), the genus lecanicillium (aphid), the genus lecanicillium (tomeyella spp), the genus ethephon (aphid), the genus calophylla (aphid), the genus Trialeurodess (trialeurodes spp), the genus Trialeurodesvaporium (trialeurodes), the genus Trialeurodescurus (greenhouses whitefly), the genus Trialeurodescurus (trialeurodes), the genus Lecanicillium (Unnasspp.) (scale), the genus Erysipelothrix (Unnasyanonensis) (arrowhead scale), and the genus Zulientreanaria. In at least some embodiments, the methods of the present application can be used to control myzus persicae (myzuspidicae).
In other embodiments, the methods of the present application may be used to control Hymenoptera (Hymenoptera) pests (ants, wasps, and bees), including, but not limited to, species of the genus phyllopohis (Acromyrrmexspp), sinomenia (athalicarosae), species of the genus phyllopop (athacumingants), species of the genus nigra (campylostomp), species of the genus phyllopodium (campylostome), species of the genus trichoderma (carpenter), species of the genus phyllopodium (diprionospp), species of the genus formica (formicasp), species of the genus argentina (irridex), species of the genus phyllopodium (argentina), species of the genus phyllopontosa (argentina), species of the genus leonurus (monophyla), species of the genus phyllopodium (monophylia), species of the genus trichoderma (monophylia), species of the genus trichoderma (monophagia (trichoderma), species of the genus trichoderma (trichoderma), trichoderma (trichoderma, Wasp species (vespaspp.) (yellow jacket), and trichogramma species (xylopsapp.) (carpenterbees).
In certain embodiments, the methods of the present application may be used to control Isoptera (Isoptera) pests (termites), including, but not limited to, species of the genus coptotermes (Coptotermesspp), species of the genus coptotermes (coptotermessvironathus), species of the genus coptotermes (coptotermessfruschii), species of the genus formosanus (coptotermessforssanus) (formosanterrantermite), species of the genus coptotermes (cornutes), species of the genus sandotermesssheets (cryptotermes), species of the genus sandotenteronetermes (cryptotermes) (coprotes), species of the genus heteroptermes (heterotermes), species of the genus sandotes (heterotermes), species of the genus coptotermes (coprotes), species of the genus sandotenteronetermes (coprotes), species of the genus coptotermes (coprotes), species of the genus coptotermes (coprotes), the species Reticulitermes (Termite), Reticulitermes batyulenensis, Reticulitermes grassei, Reticulitermes flavipes (Reticulitermes flavipes) (eastern soil-dwelling termites), Reticulitermes flavipes (Reticulitermes shaseni), West soil-dwelling termites (Reticulitermes sharsperus) (West soil-dwelling termites), Moraxella (Reticulitermes xanthonensis), North soil-dwelling termites (Reticulitermes sphaeratus), Termite (Reticulitermes), Termite (Reticulitermestica), Reticulitermes (Reticulitermesticalis), Termite (Reticulitermesticalis), Reticulitermes (Reticulitermesvirginicus), Bignonella species (Schedihinitermestesses), and white termites (Zoomophyceae).
In further embodiments, the methods of the present application may be used to control Lepidoptera (Lepidotera) pests (moths and butterflies), including, but not limited to, Aspongopus (Achoeajanata), Trichinella species (Adoxophyssopsis pp.), Trichinella gossypii (Adoxophysora melanosticta), Gekko species (Agrostis pp), cutworm (Agrostis bombycis) and cutworm (Agrotiopsis), Black cutworm (Blackcutworm), Trichinella gossypii (Alabaraella) and Cochloa (Cottonetura), Amobile unicorn, Amylothrispora, Amylothristis (Boyersinia), Trichinella (Boylostellera), Trichinella (Boylonica), Trichinensis (Boscholaris), Spodoptera (Botrytura), Spodoptera (Ostrinia), Spodopterocarpus (Botrytura), Spodopteria (Ostrinia), Spodopteria (Botrytura), Spodopteria (Ostrinia), Spira (Botrytura), Spira (Ostrinia (Botrytura), Spira (Spira), Spira (Botrytura), Spira (Spira), Spira (Spira), Spira (Spira), Spira (Spira), Spira (Spira, Capuarictoria, peach fruit moth (Carposinanniponensis) (peachfruoth), Phlebia species (Chilossp.), Mangifera indica (Choumetiaceae), Heliothis virescens (Choumetica traversasa) (mangoshaoto), Choristoneura rosea (Choristoneura eurosa) (Choristonella rosea), Heliothis virescens (Choristonella punctata (Spodoptera), Heliothis virescens (Choristoneura), Heliothis virescens (Choristonella), Heliothis virescens (Cnaphalodendrocala), Sporidia grisea (Choristonella), Sphaemaphila punctifera (Choristonella), Sphaeformis (Choristonella), Sphaerothecifera (Choristonella), Sphaemaphila punctifera (Choristonella), Sphaemaphila (Dianthus punctiferalis), Sphaemaphila ostriniata (Choristoneura), Sphaemaphila punctifera (Sphaemaphila), Sphaemaphila (Sphaemaphila), Sphaemaphila (Sphaemaphila), Sphaemaphila (, Diamond-grain species (eariaasspp.) (Heliothis armigera), Egyptian diamond-worm (eariasinula) (Egyptian gossypiella), Diamond-back diamond (eariavirustella) (roughorthohole), Ectopopira aurantiana (Ectopophyceae), southern corn seedling leaf borer (Elasmalpussosellus) (Lessocorti corchoracearum), Epiphysiphestra punctata (apple leaf moth (Lightbrough) and Pinctasia punctifera (Ephemeperemopsis), Pinctada sp (Ephemerastis punctifera), Pinctada (Ephemepella), Sphaemaphila punctifera (Osteobacilla), Sphaera punctata (Osteobacillus), Sphaerotheca (Osteobacillus), Sphaemaphysalis (Osteobacillus punctatus (Ostreta), Sphaemaphila (Osteothia), Sphaemaphysalis (Ostertagia punctifera), Sphaemaphila (Ostertagia punctifera), Sphaemaphila (Osteonella), Sphaemaphila (Ostertagia punctifera), Sphaemaphila (Ostertagia litura), Sphaemaphila (Ostertagia terrestris), Sphaemaphila (Ostertagia), Sphaemaphila (Ostertagia, The species of the genus cochinella (Helicoverpa), Helicoverpa armigera (Helicoverpa), Helicoverpa zea (Helicoverpa), Helicoverpa armigera (Heliothis virescens), Helicoverpa virescens (Helicoverpa), Helicoverpa ventralis (Helluladalis) (cabbworm), Indorella species (Indorbeslas), Helicoverpa armigera (Helioticus), Helicoverpa ventralis (Helicoverpa), Helicoverpa armigera (Helicoverpa armigera), Helicoverpa armigera (Helicoverpa ventralis) (Helicoverpa armigera granulosa), Helicoverpa armigera pinus (Helicoverpa ventralis) (Helicoverpa), Phyllostachydiplophora (Helicoverpa), Phyllosis (Helicoverpa armigera serosa), Phyllop (Helicoverpa ventralis (Helicoverpa), Phyllop granulosa (Helicoverpa armigera serosa), Phyllop (Helicoverpa armigera serosa) (Lypini (Lyophylli (Lyophyllum), Phyllop) and Phyllop (Lypini (Lyophylli plusia), Phyllop (Lypinoides (Lyophylli (Lyophyllus), Phyllop. plusia, Lypinoides (Lyophylli (Lyophyllum) and Lyophyllum (Lyophyllum), Lyophyllum) and (Lyophyllum, Pod borers (Marucanthus (Meisapela), loopers (Tolyptera), Mythimna unipunctata (Truearmyworm), Neocallinodeseliania (Lycopersicon esculentus), Ostrinia (Nymphulariaceae), Ostrinia (rice leaf borer), Ophiophaga (Ophiophaga), Ostrinia (Ostrinia), European corn borer (European corn borer), Oxydividelia, Pandemisca (common grape leaf moth (Monitorum)), Sporophyceae (Plutella), Sporophysa (Sporophyceae), Sporophyceae (Sporophytylenchus (Sporophysalis), Sporophyceae (Spodoptera), Sporophysalis (Periploca), Sporophyceae (Spodoptera), Sporophysallow (Spodoptera), Sporophysa (Periploca), Spodoptera (Periplaneta), Spodopterocarpa) and Spodopterocarpa (Periplaneta), Spodoptera (Periplaneta), Spodopterocarpa (Periploca) and Spodoptera) including Spodoptera (Periplaneta), Spodoptera) and Spodoptera (Periplaneta), Spodoptera) and Spodopterocarpa (Periplaneta), Spodoptera) and Spodopter (Periplaneta), Spodoptera) and Periplaneta (Spodopter) and Spodoptera) and Spodopter, Indian corn borer (Pludiana interpunchillella) (Indian mealmoth), plutella xylostella (Plutella xylostella), Polychlorosis viteana (grapevine moth (grapeseed), orange fruit moth (Prayendomorpha), Olive moth (Praysoleae) (Olive moth (olivetoth)), Pseudatia species (Pseudoearpa sp.), Speudaea, Spodoptera litura (Spodoptera), Spodoptera litura), Spodoptera (Spodoptera), Spodoptera litura (Spodoptera), Spodoptera ostrinia (Spodoptera), Spodoptera (Spodoptera), Spodoptera (Spodoptera), Spodoptera (Spodoptera), Spodoptera, The species Adenoptera (Synanthandonasp.) (rootborers), Therabasilides, Thermodiagematalis, Chlamydia (Tineolabisiella) (webbingclepiastosoma), Trichoplusia (Trichoplusia ni) (cabbage caterpillar), Tolypocladia lycopersica (Tutaadsoluta), Nephomydia species (Ypomenetutasp.), Coccinia coffee (Zeuzecarboffe) (red branch worm (redbranchborer)), and Periploca fusca (Zeuzypyrina) (Leopardangoth)). In at least some embodiments, the methods of the present application can be used to control spodoptera exigua.
The methods of the present application may also be used to control Mallophaga (Mallophaga) pests (feather lice), including, but not limited to, sheep lice (bovicoloovis) (sheeppbitinglouse), turkey cubeba (menacanthussramineuus) (chicken pediculus carinii), and chicken feather lice (menopongalinea) (common chicken lice).
In additional embodiments, the methods of the present application can be used to control Orthoptera (Orthoptera) pests (grasshoppers, locusts, and crickets), including, but not limited to, amadora nigra (anabristlex) (mormoncrickets), mole crickets (gryllotalpae) (mole crickets), locusta migratoria (Locustamigratoria), grasshopper species (melanopusspp), grasshopper wing sprints (microcentrumretting) (acropoda horns (angularwilford wilfordii)), Pterophylla species (pteropyspora spinosa) (kayagards), desert crugarya, cauda quinoa (scudiformaria), and blackcurrant grassland (blackcurricultura), grassland (blackland).
In other embodiments, the methods of the present application may be used to control Phthiraptera (Phthiraptera) pests (sucking lice), including, but not limited to, the species Haematopinausspp (cattle and pig lice), sheep jaw lice (Linogauthusovillus) (sheep lice), head lice (Pediculus humanus capitis) (humanbody lice), body lice (Pediculus humanus) (humanbody lice), and crab (crab lice).
In particular embodiments, the methods of the present application may be used to control fleas (Siphonaptera), including, but not limited to, canine Ctenocephalides (dog fleas), feline Ctenocephalides (cat fleas), and human fleas (human fleas).
In further embodiments, the methods of the present application may be used for controlling Thysanoptera (Thysanoptera) pests (thrips), including, but not limited to, thrips leguminosa (california) species (benthrips), thrips sikokiana (california), thrips fumonis (frankliniella fusca), thrips lucida (tobramosiphilis), thrips meliloti (frankliniella occidentalis), thrips frankliniella (franklinethrips), thrips viridis (frankliniella gillypolis), thrips viridis (thrips), thrips (thrips) and thrips species (thrips), thrips (thrips) and thrips (thrips).
The methods of the present application can be used to control thysanoptera (Thysanura) (bristles), including, but not limited to, chlamydomonas species (lepismapp.) (silverfish) and focinella species (thermobian spp.) (firefishes).
In further embodiments, the methods of the present application may be used to control acarina (Acari) (mites (mite) and ticks (tick)), including, but not limited to, woodbee shield mites (acarapisiswoodi) (cachemiteof honeybee), acarina species (acarus spp), aleyrodides (acarus uropekinensis) (acarus graciliate), mangiferous (acaramaria mangifera) (mangobova), acanthophytes species (acalepsis sp), lycophytes (acanthophytes) (tomatopsis site), acanthophytes sp (acalepisy), acanthophytes sp), acanthophytes (acanthophyceae), acanthophytes sp (acaphytes sp), acanthophytes (acaphyceae), acanthophytes sp (acanthophyceae), acanthophytes sp (mangiferous sp), acanthophytes sp (mangiferous sp), acaphytes sp (mangiferous, mangiferous (mangiferous), euonymus (mangiferous) species (mangiferous), euonymus (mangiferous) species), euonymus (mangiferous) and euonymus (mangiferous) species), euonymus (mangiferous) species), euonymus) species (mangiferous (mange), euonyx), euonymus) or mangiferous (mange), euonymus) species (mangiferous (mange), euonymus) or mangiferous (mange) or mange (mangiferous) species), euonymus) or mange (mange) or mangiferous (mang, Hornbeam tetranychus urticae (eotarychus scariensis) (yellow spider mite (yellowserimite)), gophycus species (epimereruspp.), gophycus species (erophyseppp.), hard tick species (Ixodesspp.) (tick), metetracycline species (metetrageus spp.), cat ear mite (notoederescat), ungula species (oligonychus spp.), coffee paw (oligonychus fasciatus), ilex purpurea (oligonychus fasciatus) (southern red mite)), panonychus species (panonyx fasciatus), panonychus citri (panonyx fasciatus) (red citrus red mite (citrus red mite)), panonychus ulmi (panocychu surimi) (european red mite (europeanedmite)), tetranychus citrinum (phyllocoptrutaloeivora) (citrus rust mite (citrus runstmite)), tarsonemus tarda (polyphagoraphenus) (brazidae (braodmite)), rhipicephalus sanguineus (rhipicephalussiangueeus) (brown dog tick (brondogitek)), rhizomorpha species (rhizygussp.) (bulbmites), mange mites (sarcoptes mangifera) (itchmite), crocodile crown gall mite (tetragophenophila), tetranychus species (tetranyhu pp), tetranychus urticae (tetranychus urticae) (tresospora punctatus, varroa destructor (varroate).
In further embodiments, the methods of the present application may be used for controlling nematode (Nematoda) pests (nematodes), including, but not limited to, the species aphelenchoides (aphelenchoides besse3), nematodiasis sp (belonospora spp)), nematodides (stingnematodas), strongyloides sp (cromonellaspp), strongyloides sp (ringworms), filarias canis (difilariaimmitis), stemodera sp (xylaria spp), nematodides sp (nematodides), nematodides sp (heterodera spongiodes), nematodides sp (nematodides), nematodides sp (nematodid spp), nematodides sp (nematodid), nematodides sp (meloidogyne spp), nematodides sp (meloidogyne spp), nematodides sp (meloidogyne (melodies), nematodides (melodies), nematodides (meloidogyne (melodies), nematodides (melodies), nematodides (melodies), nematode (melodies, nematodes), nematode (melodies), nematode (melodies, nematode, nematodes), nematode (melodies, nematode (nematodes), nematode (melodies), nematode (nematodes), nematode (, And banana renal nematode (rotylenchus reniformis) (nephroid-shaped nematode).
In at least some embodiments, the methods of the present application can be used to control at least one pest and at least one pest from the order acarina (Acari) of one or more of the following orders: lepidoptera (Lepidoptera), Coleoptera (Coleoptera), Hemiptera (Hemiptera), Thysanoptera (Thysanoptera), Isoptera (Isoptera), Orthoptera (Orthoptera), Diptera (Diptera), Hymenoptera (Hymenoptera), and Siphonaptera (siponaptera).
In some embodiments, a method of controlling insects may comprise applying a pesticidal composition to the vicinity of an insect population, wherein the pesticidal composition comprises a synergistically effective amount of a combination of a juvenile hormone mimicking compound and a pesticide selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof, and wherein the insects are sap feeding insects (sapfeedeninginsects), chewing insects (chewinginsects), or combinations thereof.
In other embodiments, a method of controlling insects may comprise applying an insecticidal composition to the vicinity of an insect population, wherein the insecticidal composition comprises a synergistically effective amount of a combination of pyriproxyfen (pyriproxyfen) and an insecticide selected from the group consisting of N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof, and wherein the insect is a sap-sucking insect, a chewing insect, or a combination thereof.
In other embodiments, a method of controlling diamondback moth (plutella xylostella) may comprise applying an insecticidal composition proximate to a population of diamondback moths, wherein the pesticidal composition comprises a synergistically effective amount of a juvenile hormone mimicking compound in combination with a pesticide, the insecticide is selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof.
In a particular embodiment of the present disclosure, the insecticidal composition may be used in combination (e.g., in the form of a compositional mixture, or applied simultaneously or sequentially) with one or more compounds having acaricidal, algicidal, avicidal, bactericidal, fungicidal, herbicidal, insecticidal, molluscicidal, nematicidal, rodenticidal and/or virucidal properties.
In certain embodiments of the present disclosure, the pesticidal composition may be used in combination (e.g., in a compositional mixture, or applied simultaneously or sequentially) with one or more compounds that are antifeedants, bird repellents, chemosterilants, herbicide safeners, insect attractants, insect repellents, mammal repellents, mating disrupters, plant activators, plant growth regulators, and/or synergists.
The pesticidal compositions of the present disclosure exhibit a synergistic effect, the less pesticidally effective amount of the combined active compounds provides superior pest control when compared to the juvenile hormone mimic compound or pesticide alone, the insecticide is selected from N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) thio) propanamide (I), N- (3-chloro-1- (pyridin-3-yl) -1H-pyrazol-4-yl) -N-ethyl-3- ((3,3, 3-trifluoropropyl) sulfinyl) propanamide (II), or any agriculturally acceptable salt thereof.
The pesticidal compositions of the present disclosure can have high synergistic pest control and allow lower effective dosage rates, increased environmental safety, and reduced incidence of pest resistance.
The following examples serve to explain embodiments of the present invention in more detail. These examples should not be construed as exhaustive or exclusive as to the scope of the disclosure.