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CN105525367A - Electrostatic spinning pressure spray device simulating atrium and ventricle principle and electrostatic spinning system - Google Patents

Electrostatic spinning pressure spray device simulating atrium and ventricle principle and electrostatic spinning system
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CN105525367A
CN105525367ACN201610089461.XACN201610089461ACN105525367ACN 105525367 ACN105525367 ACN 105525367ACN 201610089461 ACN201610089461 ACN 201610089461ACN 105525367 ACN105525367 ACN 105525367A
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chamber
cavity
solution space
solution
principle
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CN105525367B (en
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张小英
刘雷艮
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Suzhou Institute of Trade and Commerce
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Suzhou Institute of Trade and Commerce
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Translated fromChinese

本发明提供了一种仿心房心室原理的静电纺丝压力喷装置,包括房腔、室腔、房腔挤压机构和室腔挤压机构,所述房腔通过一个第一单向阀与溶液源连通,所述室腔通过一个第二单向阀与所述房腔连通;所述室腔上设有喷射口;所述房腔内的房腔溶液空间由所述房腔挤压机构实现压缩和舒展;所述室腔内的室腔溶液空间由所述室腔挤压机构实现压缩和舒展;所述房腔和室腔的连通关系使得:所述房腔溶液空间的溶液能够随着所述房腔溶液空间的压缩和室腔溶液空间的舒展通过所述第二单向阀传至所述室腔溶液空间内;所述室腔溶液空间的溶液能够通过所述室腔溶液空间的压缩自所述碰射口碰射而出。

The invention provides an electrospinning pressure spraying device imitating the principle of atrium and ventricle, comprising an atrium, a chamber, an atrium extrusion mechanism and a chamber extrusion mechanism, and the atrial cavity is connected with a solution source through a first one-way valve communication, the chamber is communicated with the chamber through a second one-way valve; the chamber is provided with an injection port; the chamber solution space in the chamber is compressed by the chamber extrusion mechanism and stretching; the chamber solution space in the chamber is compressed and stretched by the chamber extrusion mechanism; the communication relationship between the chamber and the chamber makes: the solution in the chamber solution space can follow the The compression of the chamber solution space and the expansion of the chamber solution space are transmitted to the chamber solution space through the second one-way valve; the solution in the chamber solution space can be transferred from the chamber solution space to the Said to shoot out of the mouth.

Description

The electrostatic spinning pressure spray apparatus of imitative atrial ventricle principle and electrostatic spinning system
Technical field
The present invention relates to electrostatic spinning field, particularly relate to electrostatic spinning pressure spray apparatus and the electrostatic spinning system of a kind of imitative atrial ventricle principle.
Background technology
Electrostatic spinning is a kind of special fiber fabrication process, and polymer solution or melt carry out jet spinning in highfield.Under electric field action, the drop at syringe needle place can become taper shape (i.e. " taylor cone ") from spherical, and obtains fiber filaments from conical tip extension.This mode can produce the polymer filaments of nanometer grade diameter.
Of the prior artly touch injection device, be mostly to adopt pump pressure principle to carry out, but the fluid concentrations stability of its spraying liquid is not good enough, and in spraying process, solution easily volatilizees and solidifies, and finally can affect the product that electrostatic spinning obtains.
Summary of the invention
The technical problem to be solved in the present invention how to solve electrostatic spinning solution volatile problem with solidifying in spraying process.
In order to solve this technical problem, the invention provides the electrostatic spinning pressure spray apparatus of a kind of imitative atrial ventricle principle, comprise chamber, room, chamber, chamber, room pressing mechanism and chamber pressing mechanism, chamber, described room is communicated with source of solvent by first check valve, and described chamber is communicated with chamber, described room by second check valve; Described chamber is provided with jet;
Chamber, room solution space in chamber, described room realizes compression by chamber, described room pressing mechanism and unfolds; Chamber solution space in described chamber realizes compression by described chamber pressing mechanism and unfolds;
The connected relation of chamber, described room and chamber makes: the solution of chamber, described room solution space can reach in described chamber solution space by described second check valve along with the compression of chamber, described room solution space and unfolding of chamber solution space; The solution of described chamber solution space can be touched penetrate from the described loophole that touches by the compression of described chamber solution space.
Optionally, the electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit, described control circuit is configured to drive described room chamber pressing mechanism and the work of chamber pressing mechanism successively, solution is made first to be reached chamber, described room solution space, reach chamber, described room solution space with the compression of chamber, described room solution space and unfolding of chamber solution space by described second check valve again, the compression finally with described chamber solution space is touched and is penetrated from the described loophole that touches and go out.
Optionally, the electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit and controlled valve, and described controlled valve is connected with described second check valve, and is controlled by described control circuit.
Optionally, the electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit and source of solvent valve, and described source of solvent valve is connected with described first check valve, and is controlled by described control circuit.
Optionally, chamber, described room pressing mechanism comprises retractable driving device and piston structure, described piston structure is located in chamber, described room, realizes the compression of chamber, room solution space and unfold by linear slide, and described piston structure drives linear slide by described retractable driving device.
Optionally, described chamber pressing mechanism comprises retractable driving device and piston structure, described piston structure is located in described chamber, realizes the compression of chamber solution space and unfold by linear slide, and described piston structure drives linear slide by described retractable driving device.
Optionally, chamber, the room flexible structure and chamber flexible structure with two openings is respectively equipped with in described room chamber solution space and chamber solution space, an opening of described chamber flexible structure is communicated with described jet, another opening is by an open communication of described second check valve and chamber, described room flexible structure, and another opening of chamber, described room flexible structure is communicated to described source of solvent by described first check valve;
Described solution circulates in described flexible structure, and chamber, described room flexible structure realizes compression by chamber, described room pressing mechanism and unfolds; Described chamber flexible structure realizes compression by described chamber pressing mechanism and unfolds.
Optionally, the electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit, and described jet is provided with injection valve, and described injection valve is controlled to open and close by described control circuit.
Optionally, the electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit, the quantity of described chamber and chamber pressing mechanism is at least two, the quantity of Qiang Hefang chamber, described room pressing mechanism is one, described control circuit is configured to chamber solution space corresponding to the different described chamber pressing mechanism compression of first rear drive, sprays with the priority realizing different jet.
Optionally, chamber, described room, chamber, room pressing mechanism, chamber are identical with chamber pressing mechanism quantity.
Present invention also offers a kind of electrostatic spinning system, include the electrostatic spinning pressure spray apparatus of imitative atrial ventricle provided by the invention principle.
Operational Mechanisms between atrial ventricle is applied in the present invention by the present invention, solution reaches chamber after being stored by Qiang Jingfang chamber, room, solution in chamber is finally by pressing mechanism extruding ejection, the solution that can realize rhythmicity sprays, and whole Process liquor is in stable dynamic, electrostatic spinning solution of its supply is not volatile and solidify in spraying process.In addition, owing to present invention employs two check valves, the solution of chamber can not allow backflow, thus makes compression and unfold the transmission that can realize solution.
Accompanying drawing explanation
Fig. 1 and Fig. 2 is the schematic diagram of the electrostatic spinning pressure spray apparatus of the imitative atrial ventricle principle that one embodiment of the invention provides respectively;
In figure, chamber, 10-room; 20-chamber; 11-source of solvent valve; The controlled valve of 21-; 12-first check valve; 22-second check valve; Chamber, 13-room flexible apparatus; 23-chamber flexible apparatus; 14,24-piston structure; 15,25-retractable driving device; 26-jet; 27-pipeline; 3-control circuit.
Detailed description of the invention
Below with reference to Fig. 1 and Fig. 2, by two embodiments, the electrostatic spinning pressure spray apparatus of imitative atrial ventricle provided by the invention principle and electrostatic spinning system are described in detail, it is optional embodiment of the present invention, can think, those skilled in the art, in the scope not changing the present invention's spirit and content, modify to it and polish.
Please refer to Fig. 1 and Fig. 2, the invention provides the electrostatic spinning pressure spray apparatus of a kind of imitative atrial ventricle principle, comprise chamber, room 10, chamber 20, chamber, room pressing mechanism and chamber pressing mechanism, chamber, described room 10 is communicated with source of solvent by first check valve 12, and described chamber 20 is communicated with chamber, described room 10 by second check valve 22; Described chamber 20 is provided with jet 26;
Chamber, room solution space in chamber, described room 10 realizes compression by chamber, described room pressing mechanism and unfolds; Chamber solution space in described chamber realizes compression by described chamber pressing mechanism and unfolds; About how to realize compression and unfold, hereafter have specific embodiment and do expansion elaboration, but, should think, as long as compression can be realized and unfold, be exactly the optional scheme of the present invention, and be not limited only to enumerate.
The connected relation of chamber, described room 10 and chamber 20 makes: the solution of chamber, described room solution space can reach in described chamber solution space by described second check valve 22 along with the compression of chamber, described room solution space and unfolding of chamber solution space; The solution of described chamber solution space can be touched penetrate from the described loophole 26 that touches by the compression of described chamber solution space.
In optional embodiment of the present invention, the electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit 3, described control circuit 3 is configured to drive described room chamber pressing mechanism and the work of chamber pressing mechanism successively, solution is made first to be reached chamber, described room solution space, reach chamber, described room solution space with the compression of chamber, described room solution space and unfolding of chamber solution space by described second check valve 22 again, the compression finally with described chamber solution space is touched and is penetrated from the described loophole 26 that touches and go out.Its core is that driving work exists suitable interval, in order to realize corresponding interval, Programming can be carried out to the control chip of circuit, also can be realized by the layout of delayer, when knowing its concrete function, those skilled in the art have scheme can realize these functions naturally, so, at this without the need to doing too much elaboration.
In the present invention one optional embodiment, the electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit 3 and controlled valve 21, and described controlled valve 21 is connected with described second check valve 22, and is controlled by described control circuit 3.The electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit 3 and source of solvent valve 11, and described source of solvent valve 11 is connected with described first check valve 12, and is controlled by described control circuit 3.The electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit, and described jet 26 is provided with injection valve, and described injection valve is controlled to open and close by described control circuit.In this embodiment, for the circulation of solution, also arrange controlled valve 21 and source of solvent valve 11 controls, to strengthen the control to solution circulation.
About the Mechanical Driven mode compressed and unfold, chamber, described room pressing mechanism comprises retractable driving device 15 and piston structure 14, described piston structure 14 is located in chamber, described room 10, realize the compression of chamber, room solution space by linear slide and unfold, described piston structure 14 drives linear slide by described retractable driving device 25.Same, described chamber pressing mechanism comprises retractable driving device 25 and piston structure 24, described piston structure 24 is located in described chamber 20, realizes the compression of chamber solution space and unfold by linear slide, and described piston structure 24 drives linear slide by described retractable driving device 25.In further embodiment, described retractable driving device 25 can adopt air cylinder device.In other embodiment of the present invention, also can adopt rotary motion, the means such as the expansion of flexible thing compress chamber, room solution space and chamber solution space.
In optional embodiment of the present invention, in order to realize the sealing circulation of solution, chamber, the room flexible structure 13 and chamber flexible structure 23 with two openings is respectively equipped with in described room chamber solution space and chamber solution space, an opening of described chamber flexible structure 23 is communicated with described jet 26, another opening is by the open communication of described second check valve 22 with chamber, described room flexible structure 13, and another opening of chamber, described room flexible structure 13 is communicated to described source of solvent by described first check valve 12; Described solution circulates in described flexible structure, and chamber, described room flexible structure 13 realizes compression by chamber, described room pressing mechanism and unfolds; Described chamber flexible structure 23 realizes compression by described chamber pressing mechanism and unfolds.
For chamber, room flexible apparatus 13 and chamber flexible apparatus 23, in optional embodiment of the present invention, telescoping tube can be adopted, in other alternative-embodiments, also the sack of specific compliance material can be adopted, be not limited thereto two kinds also, about the mode of communicating between chamber, room flexible apparatus 13 and chamber flexible apparatus 23, please contrast the embodiment with reference to figure 1 and Fig. 2 signal, in the embodiment of Fig. 1 signal, its link position lays respectively at the top of chamber, room flexible apparatus 13 and chamber flexible apparatus 23, it is communicated with by hard tube, relevant valve is arranged on hard pipeline 27, in the embodiment of Fig. 2 signal, its link position lays respectively at the top of chamber, the room solution space of chamber solution space and the bottom of chamber, room solution space, in the illustrated embodiment, because piston structure 24 compresses from bottom to top, so, can be picked out by soft pipeline 27 bottom its chamber, room solution space, want with displacement when meeting stretching motion, just schematic diagram is given in figure, and non-fully quantizes to design accurately.By above two embodiments, be intended to signal, concrete connection means, link position can do according to actual conditions change completely, such as, link position also can be arranged in the centre position of chamber, room flexible apparatus 13 and chamber flexible apparatus 23, and does the fixing of position, chamber, a relative room to centre position.
In optional embodiment of the present invention, such as, in the embodiment of Fig. 1 and Fig. 2 signal, chamber, described room 10, chamber, room pressing mechanism, chamber 20 are identical with chamber pressing mechanism quantity, and namely it is and arranges one to one.
In another optional embodiment of the present invention, the electrostatic spinning pressure spray apparatus of described imitative atrial ventricle principle also comprises control circuit 3, the quantity of described chamber 20 and chamber pressing mechanism is at least two, the quantity of chamber, described room 10 and chamber, room pressing mechanism is one, described control circuit 3 is configured to chamber solution space corresponding to the different described chamber pressing mechanism compression of first rear drive, sprays with the priority realizing different jet 26.
Present invention also offers a kind of electrostatic spinning system, include the electrostatic spinning pressure spray apparatus of the imitative atrial ventricle principle that any embodiment of the present invention provides.
In sum, Operational Mechanisms between atrial ventricle is applied in the present invention by the present invention, solution reaches chamber after being stored by Qiang Jingfang chamber, room, solution in chamber is finally by pressing mechanism extruding ejection, the solution that can realize rhythmicity sprays, and whole Process liquor is in stable dynamic, electrostatic spinning solution of its supply is not volatile and solidify in spraying process.In addition, owing to present invention employs two check valves, the solution of chamber can not allow backflow, thus makes compression and unfold the transmission that can realize solution.

Claims (10)

Translated fromChinese
1.一种仿心房心室原理的静电纺丝压力喷装置,其特征在于:包括房腔、室腔、房腔挤压机构和室腔挤压机构,所述房腔通过一个第一单向阀与溶液源连通,所述室腔通过一个第二单向阀与所述房腔连通;所述室腔上设有喷射口;1. An electrospinning pressure spraying device imitating the principle of atrium and ventricle is characterized in that: comprise chamber cavity, chamber chamber, chamber cavity extruding mechanism and chamber cavity extruding mechanism, described chamber cavity is connected with the first one-way valve by a first The solution source is communicated, and the chamber is communicated with the chamber through a second one-way valve; the chamber is provided with an injection port;所述房腔内的房腔溶液空间由所述房腔挤压机构实现压缩和舒展;所述室腔内的室腔溶液空间由所述室腔挤压机构实现压缩和舒展;The chamber solution space in the chamber is compressed and stretched by the chamber extrusion mechanism; the chamber solution space in the chamber is compressed and stretched by the chamber extrusion mechanism;所述房腔和室腔的连通关系使得:所述房腔溶液空间的溶液能够随着所述房腔溶液空间的压缩和室腔溶液空间的舒展通过所述第二单向阀传至所述室腔溶液空间内;所述室腔溶液空间的溶液能够通过所述室腔溶液空间的压缩自所述碰射口碰射而出。The communication relationship between the chamber and the chamber enables: the solution in the chamber solution space can be transmitted to the chamber through the second one-way valve along with the compression of the chamber solution space and the expansion of the chamber solution space In the solution space; the solution in the solution space of the cavity can be ejected from the injection port through the compression of the solution space of the cavity.2.如权利要求1所述的仿心房心室原理的静电纺丝压力喷装置,其特征在于:还包括控制电路,所述控制电路被配置成能够依次驱动所述房腔挤压机构和室腔挤压机构工作,使得溶液先被传至所述房腔溶液空间,再随所述房腔溶液空间的压缩和室腔溶液空间的舒展通过所述第二单向阀传至所述房腔溶液空间,最后随所述室腔溶液空间的压缩自所述碰射口碰射而出。2. The electrospinning pressure spraying device imitating the principle of atrium and ventricle according to claim 1, characterized in that: it also includes a control circuit configured to sequentially drive the chamber extrusion mechanism and the chamber extrusion mechanism. The pressure mechanism works, so that the solution is firstly transmitted to the solution space of the chamber cavity, and then transmitted to the solution space of the chamber cavity through the second one-way valve with the compression of the solution space of the chamber cavity and the stretching of the solution space of the chamber cavity, Finally, with the compression of the solution space in the chamber, it is ejected from the ejection port.3.如权利要求1所述的仿心房心室原理的静电纺丝压力喷装置,其特征在于:还包括控制电路和受控阀门,所述受控阀门与所述第二单向阀串联,且由所述控制电路控制。3. The electrospinning pressure spraying device of imitating atrial ventricle principle as claimed in claim 1, is characterized in that: also comprise control circuit and controlled valve, described controlled valve is connected in series with described second one-way valve, and controlled by the control circuit.4.如权利要求1所述的仿心房心室原理的静电纺丝压力喷装置,其特征在于:还包括控制电路和溶液源阀门,所述溶液源阀门与所述第一单向阀串联,且由所述控制电路控制。4. The electrospinning pressure spraying device imitating the principle of atrial ventricle as claimed in claim 1, characterized in that: it also includes a control circuit and a solution source valve, and the solution source valve is connected in series with the first one-way valve, and controlled by the control circuit.5.如权利要求1所述的仿心房心室原理的静电纺丝压力喷装置,其特征在于:所述房腔挤压机构包括伸缩驱动装置与活塞结构,所述活塞结构设于所述房腔内,通过直线滑动实现房腔溶液空间的压缩和舒展,所述活塞结构由所述伸缩驱动装置驱动直线滑动。5. The electrospinning pressure spraying device imitating the principle of atrium and ventricle according to claim 1, characterized in that: the atrial cavity extrusion mechanism comprises a telescopic drive device and a piston structure, and the piston structure is arranged in the atrial cavity Inside, the compression and stretching of the chamber solution space is realized by linear sliding, and the piston structure is driven to linearly slide by the telescopic drive device.6.如权利要求1所述的仿心房心室原理的静电纺丝压力喷装置,其特征在于:所述室腔挤压机构包括伸缩驱动装置与活塞结构,所述活塞结构设于所述室腔内,通过直线滑动实现房腔溶液空间的压缩和舒展,所述活塞结构由所述伸缩驱动装置驱动直线滑动。6. The electrospinning pressure spraying device imitating the principle of atrium and ventricle as claimed in claim 1, characterized in that: the cavity extrusion mechanism includes a telescopic drive device and a piston structure, and the piston structure is arranged in the cavity Inside, the compression and stretching of the chamber solution space is realized by linear sliding, and the piston structure is driven to linearly slide by the telescopic drive device.7.如权利要求1所述的仿心房心室原理的静电纺丝压力喷装置,其特征在于:所述房腔溶液空间和室腔溶液空间内分别设有具有两个开口的房腔柔性结构和室腔柔性结构,所述室腔柔性结构的一个开口与所述喷射口连通,另一个开口通过所述第二单向阀与所述房腔柔性结构的一个开口连通,所述房腔柔性结构的另一个开口通过所述第一单向阀连通至所述溶液源;7. The electrospinning pressure spraying device of imitating atrium and ventricle principle as claimed in claim 1, is characterized in that: the room cavity flexible structure with two openings and the cavity cavity are respectively provided with in the cavity solution space and the cavity solution space A flexible structure, one opening of the chamber flexible structure communicates with the injection port, the other opening communicates with an opening of the chamber flexible structure through the second one-way valve, and the other opening of the chamber flexible structure an opening communicating with the solution source through the first one-way valve;所述溶液流通于所述柔性结构中,所述房腔柔性结构由所述房腔挤压机构实现压缩和舒展;所述室腔柔性结构由所述室腔挤压机构实现压缩和舒展。The solution circulates in the flexible structure, and the chamber flexible structure is compressed and stretched by the chamber extrusion mechanism; the chamber flexible structure is compressed and stretched by the chamber extrusion mechanism.8.如权利要求1所述的仿心房心室原理的静电纺丝压力喷装置,其特征在于:还包括控制电路,所述喷射口设有喷射阀门,所述喷射阀门由所述控制电路控制启闭。8. The electrospinning pressure spraying device imitating the principle of atrial ventricle as claimed in claim 1, characterized in that: it also includes a control circuit, and the injection port is provided with an injection valve, and the injection valve is controlled and opened by the control circuit. close.9.如权利要求1所述的仿心房心室原理的静电纺丝压力喷装置,其特征在于:还包括控制电路,所述室腔和室腔挤压机构的数量为至少两个,所述房腔和房腔挤压机构的数量为一个,所述控制电路被配置成能够先后驱动不同的所述室腔挤压机构压缩对应的室腔溶液空间,以实现不同喷射口的先后喷射。9. The electrospinning pressure spraying device imitating the principle of atrium and ventricle as claimed in claim 1, characterized in that: it also includes a control circuit, the number of the cavity and cavity extrusion mechanism is at least two, and the cavity of the cavity is at least two. The number of chamber extrusion mechanisms is one, and the control circuit is configured to sequentially drive different chamber extrusion mechanisms to compress corresponding chamber solution spaces, so as to realize sequential injection of different injection ports.10.一种静电纺丝系统,其特征在于:包括如权利要求1至9任意之一所述的仿心房心室原理的静电纺丝压力喷装置。10. An electrospinning system, characterized in that it comprises the electrospinning pressure spray device according to the principle of imitating atrium and ventricle according to any one of claims 1 to 9.
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